Document J3BkRqb5E5vJQ3XDJwjkoXqpa

FILE NAME: Chemical Abstracts (CHAB) DATE: 1968 DOC#: CHAB056 OCUMENT DESCRIPTION: Abstract Originally Published in 1963 by Sluis-Cremer 4.y; neaitny nonexposed controls, 98.7% of the leukocytes showed a polarographic method involving the Brdicka reaction'was useful. green fluorescence in Ilg light according to the method of Meisel The anal, method was adapted from Mueller (CA 59, 54501).) and Sondak (7-1 50, 10928a). This value dropped to 89.0% using a dropping mercury electrode. I'olarograms were recorded in 27 persons exposed to CtH for 3 months to 2 years und to 86.1% between --0.8 and --1.9 v. William L. Downs in 29 persons exposed for 2-21 years. The above change, at- Sudden death in erplosive manufacturing workers (exposed to tributed to altered nuclear DN'A, is produced also by other n nitrogh rerol and ethylene dinitroglycol). P. Carmichael and hematopoiesis-affecting toxic agents, esp. ionizing radiation. J. Lieben. Intern. Congr. Occupational Health, 14th, Madrid. Although nonspc'ific, the fluorescence method is markedly 1963(2), 514-l((Pub. 1964)(Eng); cf. C.I 60, 2245d. Old earlier in the detection of harmful CH exposure than the PhOH and new data on chronic toxic effects of the 2 title compds., test of Teisinger and Bergerova-Fiserova (C.I 49, 556flg) or the (1) and (II) resp., are given. In 4 new cases of sudden death clin. methods, and therefore has diagnostic value. _from coronary arteriosclerosis in men under 45 years of age, L. J. Urbanek exposure to I or II appeared to be involved. Possible chronic Skin disease from color developers.Lionel Fry. Brit. J. toxic mechanisms of action of I and II (with and without a fatal Dermatol. 77, 450-(il(1956)(Eng); cf. Kuudsen Arch. Dermatol. result) are considered. W. C. Tobie 89(3), 357- 9(1904). Studies were conducted on 20 patients A pathological-radiological correlation in 108 cases of asbestusis with skin reactions presumably attributable to contact with proved post mortem. G. K. Sluis-Cremer and J. C. Wagner photographic color developers (2-amino-5-(diethylamino)toluenc- b (Miners' Med. Bur., Johannesburg, So. Africa). Intern. HC1, 4-amino-fV-cthyl-iV-(0-mcthylsulfamidoethyl)-w-toluidinc Congr. Occupational Health, 14th, Madrid 1963(2), 608-10(Pub. scsquisulfatc-HjO, 4-amino-AT.iV-diethylaniline sulfate, and N- 1964)(Eng). Cases resulting from work in the crocidolite (blue ethyl-AMS-hydroxyamylF/i-phenylenediaminc-HjSCh). Thir- asbestos) or amosite mines in South Africa are described. These teen of the patients showed eczematous eruptions, and all but minerals occur in banded ironstone eontg. up to 40% free SiOj. 1 showed a pos. reaction to patch tests with 1 or more of the Mill dust may contain as much as 20% SiCb. Important amts, compds. Seven patients had lichenoid eruptions, and 4 of these -- of Fe minerals (discussed) arc also present. Asbcstosis resulting gave pos. patch-test responses. Only one patient reacted to p- phenylenediamine itself. F. postulates a combination of toxic and allergic mechanisms to account for the lichenoid manifesta tion. Fred H. Snyder Sensitization of skin by chromium. Z. Mikulecky (Kozni Oddeleni, Kolin, Czech.). Ccsk. Dermatol. 40(5), 318-21(1905) (Czech). A review of the mechanism and pathogenic significance. 16 references. L. J. Urbanek Hygienic aspects of arc welding with basic electrodes. L. Hanslian (Okresni Hyg. Epidemiol. Stanicc, OloinOuc, Czech.). Cesh. Hyg. 10(8), 490-6(19G5)(Czech). F compds., nitrous, gase', CO, H2O2, and Oj are the most noxious products arising in the work with ru'ile-coated electrodes contg. alk. fluorides. Temps, of 5000-6000 and radiation produced by the arc favor the formation of oxides and irritating aerosols. L. J. Urbanek from the inhalation of such dusts is frequently atypical, and nearly 33% of the cases with moderate asbcstosis cannot be demon strated by x-ray. W. C. Tobie Odor control at a 2,4-D prodt tion plant. T. B. Henshaw (Chipinan Client. Co., Portland, Ore.). J . Air Pollution Control Assoc. 15(11), 516-18(19G5)(Eng). Chlorinated phenolic hy drocarbons used as intermediates in the manuf. of 2,4-D and re lated herbicides have an unusual odor with a low threshold of de tection. This odor-control problem was solved by fume collec tion and scrubbing with 5-8% caustic soda soln. The scrubbing has removed the phenolic compds. from the plant exhaust air to an acceptable level from the odor release standpoint. A no. of kinds of ducting material, such as rubber-lined steel, transitc, and stainless steel, were tried and found unsatisfactory. The system finally designed and installed uses heavy-walled transitc pipe Blood antibody titer as an indicator of chronic effect exercised (_c_lass 2400 sewer .pi.pe). with the p. ip. e itself serving.. as a g.asket sur- by chemicals encountered in the plastics industry. M. M. Ko- d face. Clamped-011 flanges and asbestos gaskets are used. Re chanov (Inst. Polymerization Plastic Materials, Leningrad), cent tests on fiberglass pnipne reinforced with furatnt resin indiiccaat<te Gigiena Truda i Prof. Zaoolevaniya 9(8), 27-31(1965)(Russ). this to be a superior material. Operating experience and flow The action of trifluoroethylene (I) and of products of thermo- diagrams are given. Russel H. Hendricks oxidn. destruction of pcntaplast (a polymeric material, (II)) Instructions of the chief hygiene officer in Czechoslovakia re was examd. by detn. of the antibody titer in rabbits. I (0.05 garding the evaluation of atmospheric contamination in work ing./l.) was administered by 4-hrs.-daily inhalation for 4 months, shops [handling trichloroethylene and formaldehyde). Pavel the 47th day a vaccine of typhus abdominalis was injected sub Pinta (Okresna Hyg. Epidemiol. Staniea, N'itra, Czech.). cutancously, and the titers of O- and H-agglutinins was followed. P-racovni Lehar. 17(6), 253-6(1965)(Slo). The values detd. in 7 II, contg. CO 0.03, chloroanhydridcs, including COCI2, 0.001, dry-cleaning establishments and 5 plywood manufg . plants using and aldehydes 0.001 m g./l. were administered 4 hrs. daily for urea-HCHO glues are tabulated and the results of exposure tests 5 months, the 43rd and 112th day the tetravaccine (typhus, e correlated. . L. -J. Urba.nek paratyphus, Shigella flexneri, and A. sonnet) was applied, and Phthalic acid esters m the atmosphere in the processmg of the antibody titer was followed by macroagglutination reaction poly(vinyl chloride). Josef Zdrazil and Frantisek Picha (Okresna The I chronic action increased the O-agglutinin titer and decreased Hyg. Epidemiol. Staniea, Gottwaldov, Czech.), 'acovni Lekar. the H titer. Under the latter expt. the antibody titers were 17(6), 257-60(1965)(Czech). The concn. of phthalates was detd. lowered. This technique may be used for diagnosis of chronic by sucking the atin. through membrane ultrafilters, dissolving poisoning in the plastic industry. Ivo Hynic -- the retained particles in 75% EtOH, and estg. polarograpliicalty Functional condition of the stomach and external secretory in 0.5M EtiNBr. The highest values were 2.86-5.84 m g./m .5 activity of the pancreas in workers exposed to the effects of nitro in the rolling of sheets and up to 44.0 mg./m.5air in the produc derivatives of benzene. A. I. Kleiner, E. V. Krylova, and A. M. tion of floor covers, and caused marked irritation of the con Levendyuk. Gigiena Truda i Prof. Zabolevaniya 9(9), 40-7 junctiva and upper respiratory passage, esp. at temps. > 30. ( 1965)(Russ). Under examn. were 70 persons who had worked L. J. Urbanek with the title compds. more than 3 years. Clin, hepatomegaly, 1 Toxicity of kukersol and a bitumen-kukersol mastic. Kh. E. astheno-vegetative syndrome, pigmentation of skin and hair, Kyunamyag. Vopr. Gigieny Truda v Slants. Prom. Est. SSR, and special bilateral cataracts connected with unchanged vision Tallin, Sb. 1964(5), 129-43(Estonian). The varnish, kukersol were observed` i'n most cases. By_ further examn.,. hy. p. ochro.m.ic (I), is used in house painting and in the compn. of a bitumen- anemia was found in 10%, reticulocytosis in 15, leukocytosis in k--u--k-e--r-s-o--l--m--a--s-t-i-c (.I.I) for .g.luin.g. floors and .plastic coverings.. I,t is 20, pain in the epigastrium in 77, hyposecretiou of gastric juice__the product of copolymerization of HCHO with unsatcl. nyuro- in '33, hypersecretion in 12, hypo- or anacidity in 33, hyper- carbons and phenols of high-boiling fractions of tunnel shale tar acidity in 20, decreased enzymic function of stomach in 10-14, and is used in so`in, of rectified low-boiling fractions of shale tar changes in motor function of the stomach in 10-45, roentgeno (b. range 154-225). The volatility of I at 20 is about half that logical changes of the stomach in 15, a lowering of trypsin, of the high-boiling fraction of tunnel shale tar; at 50 the volaamylase, and lipa,,s,,e a...c.t.i.v...i.t.ie.s i.n. . d__u_o_d_e_n_al,,j_u_i_c_e_i_n_35,. 15,. and 7,. tilities of these 2 substances is approx, the same, while at 100 and r e s p m i hierease^f'those enzymes activities after intradiiodenal g 150 the volatility of I is higher. Median lethal concn. for mice 0.25% HC1 administration in 40, 35, and 15, and pathol. changes iinn sseerruumm aammyyllaasseea--f-t-e-r d--o-u--b--l-e -administration of _glucose in.72% of the people examd. The intensity of pathol. changes is re lated to the time of exposure. The functions mentioned must be considered in periodic examns. of workers in the nitro compds. industry just as in treatment of chronic occupational poisonings. Ivo Hynic was 44.6 for I and 57 m g./l. for the II (2-hr. exposure). 1he into_xic_ation picture showed narcotic, convulsive, ana irnt;ant ef fects. Exposure to 4 mg. of I and II/l. resulted in growth arrest, and increase in the wt. coeffs. of lungs and liver in mice. I also caused lymphocytosis and neutropenia. I ami to a lesser extent the II irritated the skin of rabbits and mice. No sensitization to I was observed. The II can be used for gluing floors but not Determination of atmospheric lacrimatory potential by in strumental methods. Kenneth F. Lampe (Univ. of Miami, School of Med., Coral Gables, Fla.). Ind. Med. Surg. 34(10), 797_9(4965)(Eng). Three methods involving the reaction of linoleum and similar materials, since in the latter case volatile fractions continue to be given off for a long period. Health examns. should be periodically made of workers working with II. F~ rom Ref. Zh., Ft- armak, o,l., TokL s-tLk.oil. 1965, Au b. s. .tr. . No. O2O0.54.3`l 5-O3l . the lacrimator with compds. contg. SH groups were studied. One method, which involved the amperometne titrn. of mer- rapt-ins with AirN'Oi was unsatisfactory. A method involving the polarographic detn. of unreacted mercaptan by anodic oxidn. was unacceptable1 because of inadequate sensitivity. A 2nd __ ,,rid hvsmokers Urinary excretion of 5-hydroxyindoleacetic acid by smo and nonsmokers. \ . k . Hopsu, \ . V. h. Lippanui, M. y u , and T. Vanha-Pcrttula (Univ. Turku, I-mland). axpcrieu ta 21(12), 724-5(l965)(Eng). 5-Hvdroxvmdoloarv.o :.rt u - m