Document GzZJ9mDVgV1w17Jp1vo87KKQY

Oft 21 1976 December 20, 1976 Dr. Jerry H. Johnson Acting Chief, Crltsrls Documentation, Section 1 MIOSB, DCD6D, AM 142 4676 Columbia Parkway Cincinnati, Ohio 4S226 Daar Dr. Johnson* At tha rsvlsw seating hold on Movember 30 on tha draft critarla docuaant for polychlorinated biphanyls Z was laft with tha impression that future drafts of tha document would continue to contain allegations that PCBs are human carcinogens and that they should be labeled as "cancer suspect agents" In previous opportunities to ooosient z have emphasised tha lack of persuasive evidence to provide a sound basis for designating PCBs as carcinogens. At the review meeting Dr. Paul B. Brubaker reported that tha cohort in the ongoing Mobil Bpidsmlologloal study has been reidentified and changed and that the results are now expected to differ from those initially reported. The reports, frost industrial Blotest Laboratories and the Bppley Institute, which z gave to Mr. John Pajen, contain conclusions which differ from those reached by Dr. Donate Kimbrough in her studies with female rats. It is our considered opinion that this information further emphasises the uncertainty of some of the available data and we strongly reoommend that your office reconsider its decision to continue to designate PCBs as cancer suspect ingests. . 3 oci Mr. John Pajen HXOSH bcc* R. A. Stofcc/J. C. Weber 0SW 018909 STLCOPCB4005453