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+ _-- Seeet: Puotocheniosts in Bhied Subject: Fluorochemicals in Bl~od
we wm meme coos tovesber 3, 1377 ~20 :
H.E. FREIER
- q01-1S
SE Ihe Dae J.D. LAZERTE
- 236-1
3:5: ihe IB J.E. LONG
- 220-2E
FE i B.W. NIPPOLDT
- 201-IS
Sh inoasoss `shocie J.A. PENDERGRASS - 220-2E
FC LE R.A. PROKOP
- 236-3B
Es Shen F.A. UBEL
- 220-2R
SMa DEVE D.G. WEIBLEN
- 201-IS
November 3, 1977
rou cn. smisme = 201s FROM; J.W. BELISLE
- 201-IS
| Introduction
50 81 vioke blood sample as drawn (using multiple 10 nl A 50 ml whole blood sample was drawn (using multiple 10 ml Sateentoeel and Serine te een JTS sige 10 nL ) VCCfahhocaerummtoooallriiisnttaeeenr,,isc).ssaeenvvaeednnndioosnefforwruwmsh,a4i.n~~d,i-h,c-sw~woefe,ilrraseetoerdissdaafemmrpoplml(eerddeeipgpporhrretetvveiid3ooMuuissnellmyypS.:lhiosyeAaennLsetaatnanetaarll)yyssiiss
JI Jaanfnoidr FoPCr-g1Ea4n3icaanandandFeCio-n9os5rganc"iCoocnntcefenlnttuor((ittdooebbea(rrveeepppooerrrttteeedddinltaattteehrri))s oolnnetteceaarcc)hh
A~j~ a a ' serum sample was requested.
10{'~ Results
'
same JoEwT7,J mmm --u Eg w Rrem |
LiteraStaumrpeleRange 0.0_R0F2(-pp0m_._1) 3 0F.,0-0(3p-~m0).17
Literature Range
0.RF0,02(-p0p.m1)3 0F.-0(0p3p-m0).17
open Hitorature average 0.0002:-030.13 0.02 0.003-0.17 0.03 0.'002-0.13 0.02 0.003-0.17
0.02
0.03
0.02
tp CE 5 os te,ERBEEEN
31
0.05
00..0099
CEE Bi 1a. 00..0033
i me
10.2 0.08
Foe dio 13.0 00..0084
apt Ee
0.06
osEI
vo gprs A
O.06
5.3
00..0066
-nnoott ssaammppliecdd --
25.0 0.00 | 0.03
~ 2200.11
00..0022
{
28.8
0.01
110 wor | ii.0
0.02
5 wo | 9.6
0.02
se om | 615.8
6.1
13.8 13.8
O.O2
00..0044
|
00..0011
|
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Discussion
Somewhat surprising, all 7 persons who were previously sampled had
Beran ES oe ran ers BESSY sampled baa | the same or a slightly lower organic fluoride (RF) content a year
later. This can be interpreted in one of several ways:
(a) the employees vere not exposed to any high IF levels as they la) the employees were not exposed to any high RF levels as they
have been in the Dast.
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((b5)) ddiiffffeerreenntt ppeeooppllee,, wwhheenn eexxppoosseedd ttoo~htehe-ssaame~--l~eveel~ ooff RRFF,, rreettaaiinn
the compound(s) to a different degree (homeostasis).~
7 1c) since the levels reported range to 1000 times the "accented" (c) since the levels reported range to 1000 times the "accepted"
Ahrens" he Jevels Tobpried cangd fo L000 ime the maccent average in the general public for RF in human serum/plasma and
ta ue Ta ie hu Ey Dre erinEle mn ant aasinllcoonengga,,thelloonnlgg9evettliismmeehattvooe cclrleeeaamrrainbbeooduunnddfaRiRFFr..lf-yI_2k ~c-omn~sE ett/a~n~dtR V~Iio~ieti~Dmtdaviivkie~es5t~-h@~body
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(@ singe Lt ts understond that the nealin of nese splogess (d) since it is understood that the health of these employees
iiss nnoorrmmaall,, iitt iiss nnoott cclleear what biological or chemmiiccaall, test, other than our RF analysis, would indicate the employee is
oar seco Rimatteie- rod intleatcehesmpleves tt ene carrying such a high level of bound fluoride and especially the
significance of the finding.
~
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