Document Gmrj0OXEJQqDbajmbmKp7pVz7

T A-v t. L Air SEygdea* Foundation of America, lac. 4400 fifth Avenue, Pittsburgh, Pa* June 8, 1939 RE7ZRENC2S TO RBCQfT LI * ;Kt * OK ZHDOSTRIAL DISEASES RSSFIRa5)JP. 436 Willson Bureau of fuses of ; This is t .7 KIKES FOR LEAD POOS* circular, bar# announced the approvaJh^telie H. 3 aplrator for protection against pM^sX^oparaoiis, mercury, manganese, arsenic, ^oneipKr zinc, ate. of this typo to receive approval of tha Bureau* 437 OKI A w publication It i# to be Issued educational notorial o contains lts on the a reporting of occupational terest* by tbo Ohl<qto>*hcnt of Health, Col\bua* 11 contain informational and __ ora* Tbo first issue, April 1939, of tbo department, ooblla laboratory, state and other Itoss of general in- (B) Papers on Dust. Dust uatrlal Hygiene 43S NOTE OK AN FOR HOST Dunn* J* lad* Hyg. k Toxicol*, 21, 202-3 ( A desert?' _ .Ten of a new call fgrpjiese i*>6c\tiag impingor dust samples* Tbs ni 'cofcsists of two parts, onewblct^sA glass plate 1 . thick, groj ;b surfaces, with a central tblryf dimeter that tha cell 'approadmately 0*25 ml* The other;^& isV/Srger plate of optically illshed glass* Both are of "pyrex* glaJ^^ Aay^Stable cover glass, such those now used, may be wployed as a coter:^^B* `Tifi^ew call greatly re duces tha loea of time la cleaning and recounting the^ira&rd Sedgwick-Rafter cell* The comparatively large sealing area prevegtileaka^e of air Into the cell caused by evaporation of tbe; liquids Altho^h no Semite data baa been collect- ed to compare counts using tbe new'.cell with that Sedgwick-Rafter rou- tine plant studies have Confirmed Its apparent acourabj^^Tbe call could also be easily adapted to plankton, sewage or bacteriological swm because of tbe simplicity of and resistance to attack upon autocMJijgeterilizatioiu 439 THE RATS 07 KBIXJCTlQJf AND THE TREE SILICA CONTfifT 07 THE JlH^buST PR0HJCZD 3Y ROOD Tarrrj.Tw. a* Shaw and J*Q* Grab*. Trans* Instn* Min* Sngrs* London, 97, 104-13, (April 1939). (British). The. free silica content of fins dust is almost always less than that.of the rock from which It is formed* It is dependent also on the rate of drilling, being slightly higher the slower the rate of drilling. Tbe free silica dust produc tion expressed as gras of dust per foot of bole drilled may be token as an in dication of the slllcoels producing character of the rock* The roaulta Indicate that all rocks from which more than 23 gm* of free silica-dust are formed per foot of hole drilled should be considered harmful, and that precautions should then be taken* PLAINTIFF'S EXHIBIT EXHIBIT VVV-02107 References to Recent Literatura - 2 440 SILICOSIS AMS ITS PREVENTION* I. S* ffeldana, F. Haynes, A* Shaw and J. Q. Graham* Trane. Instn. Mia. Eagrs. London. 97, 40-67, (April 1939). (British). It is suggested that tha ton silicosis ha applied only to a fibrotle condition of tha lungs in parsons with an exposure to dust containing a high proportion (SO or acre) of free silica* Clinical and radiological examination should not ha regarded as sufficient basis for a diagnosis unless there is a reasonable history of exposure to free silica dust* Although a large nmhar of coal workers in South Wales hare bean certified asmdllcotlc, tha work-histories of the cases show that the man hare not been suhl^ctad to highly siliceous dusts* Tha pfcthl- sls^fo$h-rate mong tha coal min^U^air shown by thalr statistics, is not sij nlftda^tly hlgho population of the district* Tha cidencar^fc bro s should not be attributed to si: as has ttMi . It is npbaslzad, howwver.j;lAtMNa^in- halation ust will causa pulmonary datiHs^Tollow- Ing the sting discussions by oth^^fUjSwilties in the field* states that tha authors* daflnlWmA^r silicosis (above) is 8lltc<>fls mjfiouth Africa hare been c ill, tha paper con- trlb disease* & 441 07 THE MEDIC 1937-6* H* X. Stationary Office, London,(1939) Among the large mnbe In this report are sons dealing directly with industrial coal miners, which resables silicosis clinically, bu not compensable, whereas slll- cosis is c^Epensable contlnue the study of anthraco- sis In South Wales* on is the work of the Coa- mittee on Toxic Solv Asaoclatlon of Chsnlcal Manufactur- ers* checks at oxt-etaiM^tage the-toxici new solvents that are intro- duced* Mention^S^mp^e of a public* whl*g/S\*ari tea the literature on to^c aaiT^iOTV'^jyt TMng q very us Other less Important research- es along~idnSn>al health lines are 07 "CURIOUS BODIES" IN THE LI CAN COLO MINERS. Lisas. J. Path* * Bacteriol., 46, 4' (British), .ous bodies" is tha tern often applied structures found in >asbestotlc lungs. They are light colored, but^tijttlar' ones have been found in the lungs of coal miners. The author r*$$ts b3 on such bodies seen in the lungs of 3 South African gold alners'^N^has examined. Both light and dark colored bodies were found, and in sene lungsjboth type# wore present simultaneously* There was no constant relation, howevea^) between the presence of bodies sad silicotic findings, and Dr* lUliw is *^*?that the bodies are not significant la the development of anthraoo-sillcoals i^be cool alnars and trismers she hae examined. They are probably the result Sf^^teacs inhalation of fibers or spicules* These black cored bodies evldsntly eamffc be produced ex perimentally, although the pale asbeetotle ones cam be. 443 'THE PRODUCTION 07 DOST IN HARD HEADINGS AND MEA2B FOR ITS SUPPRESSION. I. 4* Graham, D. G. Skinner and-W. 2. Walton. Trans. Instn. Ida. Eagre. London. 97, 83-103 (April 1939). (British). Experiments ere described which illustrate the concentration! of dust in the ; chief operations involved in the driving of herd headings, nomaly drilling, shot firing and filling. The moat Important means found to reduce the dust was the use of wet drilling methods. The use of a mist projector, with a wetting agent in the spray enter, was only slightly successful. Reference*, to Recent Literature - 3 A DZ7XCZ FDR ARRZSTBO BFL0SI0N3. 8. Allsop, F. J. Hartwell and R. V. Wheeler. Trane. Instn. Via. Baer. London. 97, 20-39 (April 1939). (British). A description la given of arrangements whereby firedamp explosions in coal mines can be extinguished. The arrangements Involve the provision of (1) mortars from which a cloud of lneohustihle dust earn be projected Into the path of the explo sion, and (2) thermal relays which, whan subjected to the heat of an explosion, close an electric current which operator* the mortars. The incombustible dust found most effective consists of 80<4anon salt, 18% chalk and 2% magnesian carbppaf*. Teats made with the ag&rptn hare proved Its effectiveness. 443 B. Daly. Kin. Cong of Industrial health la not always factor in his costs. Tho natal ml is assy other Industries, la the ut one la- namely silicosis. The autho: or of Hines, traces the dust ccatrdnNmsasures of that company The paper broad discussion of control. 446 TBS DOST FRO. 18-19, 72-4, (Hay 1939). Dost control is an impo: trial anglnearlng managtoact and should be given conalderat cnee has been gnlnod during the past and industries have found t control of the dust probloa has not been prohibitive. ConsidH^^rahouiafti^jlan to dost, whether hyglenicolly significant or not, Im^fnhJpaalga. div nawvftglding* or now processes that any be potentially dustyy? fUf)Vaesats or dcuast couJn> ter^hould be made at regular intervals to eheck the of the systsasv to maintain higher oaployoe morale and find hazards. CLZAHDO HST3DD6. Fred 44-6, 92 (Hay 1939). ited description Is given of t new cleaning depart- foundry. Small castings are cl eblast machine; largo Lags ere cleaned by first removing the . v of high pressure >water, then blasting with steel shot. All dust^arrest 04^ IS by wet methods and the sludge is reclaimed. This modern installation's* ao&ooznly. almost elimln- ated the dust hazard la tha foundry, but has realigpd^a saving of over 75?t in the time of ruil ng cores in large castings* 448 practical hbhjds fob tbs control of granule ofoOBESaf^l . A. Coburn* Am. i. Pub. Health* 29, 301-6 (Hey 1939). . (h ' The author presents a sr^mary of the general oonsideretioMgjfh prevention of industrial diseases. The hazards of dust, chrcmiim, lead, ga othar material j ore discussed. The paper was presented at the October 28, 1938, meeting of the American Public Health Association in tenses City. Following tho paper is an 8-page discussion compiled by C. L* Pool ehlch swnarlzea end describee typical methods for control of exposure* In certain Industrie*. 449 BXTOHD TOST * TEB Tri'in or TS5 LAI." 3*I.fioberte. Occup. Hazards h Safety, 1, 15-18, 28, (Hay 1939). The trend of court decisions la definitely towards application of tha low, of considering an occupational dlseoso the seme as an injury, wherever jp** ciflc coverage has yet to be enacted. Cases are presented to show the devious reasoning by which the courts have mode awards for industrial disabilities and to show management why it may be wise to look beyond tha letter of the law in determining its responsibility. References to Recent Literature - 4 490 AHJCTBC IXT9T IK BITCKIllDDS-COjtt, HINES WITS WATER. D. Harrington, J. J. Forbes, 7. S. Cash, S H. Denny, 0. A* Herbert, 0. J. Parker, C. W. Owing* and A* w. Killer. tT 3. Bar. of Hines, Tech. Paper, No. 593, 93 pp. (1939). For sale by Supt. of Doctswnts, Washington, D. C. for 15 cents. This bulletin describes sore fully (sae Abstract 118, 1939) the resoarchos of the Bureau of Hines on the use of water in reducing dust in coal Bines. To pre vent dust explosions In sines both water and dusting methods are being used in conjunction. The dusting cannot be applied within 15 feet of the face, and It is at this point whtre suoh of the coaledusts and gasas ore encountered. This bulletin emaiorates the dust producii^sourcea and describes practical methods of usfog water as one of the soa%^6*elve methods of allaying dust in bitu ous^&jjl nines. 4bccelle&fe Uliutn^tons and sketches are included, the rSdt^lon af^Sust b#cu6d~0x its explosive qualities an increase o the efftdis^fy claimed in sobq sines, due both to_ri comfort Bra. coal increased visibility. 451 DZA093STIC tive Edit! the AssociktAo&^v Udres This booklet foil' bnWMBIirSSla outat physt opportunity to detect at a proper diagnosis, health but also that of _ SIS OF THE LUNDS; AND DBS. Tenta- ulosis Association, 1938. tainable from W. 50th 3t., New To 10th edition presents sispl7 and pulztsnary tuberculosis, vorteen an et should help his in arriving es sot only isprovas industrial ^ 452 TUBERCULOSIS MDRTAUTT IN IN^^^^POP^ATIONS OF KASSACEDSETTS AND KinHOAN. C. C. Dauer. As. Rev. 6plS^5\ (Mot 1939). Tuberculosis Bortalilasx^Jgp hire, baton hl^sy in four Massachusetts cities than in a similar gromo^approxlBatoly~tho ssoaeC^lZQ la Michigan. It appears that the difference tJQiftrtniity in the two-groups^f cities con best bo explained unfavorable enrirb^ant social conditions in the >upa. It also appear*<f$At^ lnlHe*ly the cospositlon of the .th respect to nationality bfcasf^"ftaye^J^pae part in thasa differences The paper includes tables and/jrtatisil^ which describe the data age groups, type of occupational ` - pulatlon and housing RETORT OF. THE DSPARTKBflAL 0Q18CTTSE ON CQKFSSm^ FORCED BOOK woflcas. H. K. Stationery Office, London, 1939. . The Canlttee was appointed to consider on equitable^espensatlon code for sard room worker* Is cotton sills. For a long tine It warn tfitaght that there was nc specific disease aaeng the operatives which could be tkMkjJect of precise clinical disgnosis, but the present Ccoaittee rec pezslsslon of mrkere to apply for compensation for a respiratory dl*eeSt'Ctoned "byseioosls," after having worked la a card roda or cotton blowing room fS~20 years or sore. It it now thought that a special medical board la able to arrive at a dafinito conclusion as to the occupational origin of this disease, which reswables bronchitis and eaphysada end which Is presumably characteristic of the occupa tion.............. ................................... '......' 454 TBS FLOW OF AIN AND ITS DIBTRIBOTION THROUGH DOCtS. PASS 4. OPCT LAZOTf. I. R. . Zwlckl. Beet, k Vent...36, 48-50. .(Kay 1939). See Abstract 378, 1939. This paper discusses the method a of duct layout and design based an technically correct methods. All sections of ths system are first calculated as equivalent round ducts and then their equivalent rectangular duets substituted, if necess ary, to fit the Structural requirsmaats of the `building. The designing is based on the flow in the selected main duct and branches are calculated as percentages of the asm. Equations for calculatingduct sizes and bend losses are included and explained. References to Recent Literature - 5 CG) Papers on Industrial Polsons, Cancer, Dermatitis, ate. 435 RESPIRATOR* HAZARDS OT ELECTRIC ARC WHXIKJ. 0. A. Sander. Ind. Mod. 8. 177-80 (May 1939). Twaty yoars of electric welding experience sea to indicate that the operation is sot a hazardous occupation provided the fuse concontratlon is kept below a certain level* This danger level appears to be higher than the concentrations of fumes usually encountered In nodeafely large and fairly well ventilated rocms. A great dtal dapends upon^Jra3Uteriala being welded and materials In the wading rods. Newer type* sraSmnrLaually bolng developed and care shoi be taMn in thej^^ of then^^on^nr the newer materials are manganese, axsenT ^ - Jr of lead poisoning Is of consoquence lals contc Welding should sot be done in coof^nq without rentllatlon even for short periods ofc^&ta^iCanuf&c- turers of analysis be of bo Ls might wall eonsldar a program of rHoaMtf in tha by tho newer electrodee; a prog^aa^ this sort would ital industry* 436 HEAL CSS. H. Chemist, IS, 187-94, >39), ^ It may ba saften asi that all. a may be potentially tone un lass daflnltaly toown otl feted that any chemical material, however toxic, can be le degree of safety If its toxicity Is known and the i^lcati s are followed, Tha author dlscuss- es the hazards of tone si portals of entry Into the body, the chemical and physical staj oents act and the organs generally affected. A program 1; sg the Iraowa hazards and for eval- unting tho unknown The latter gesorally Involves lenghthy.' expei to detenlne acute and chronic effects, tectlve measi fo of tone materials is includ- ed. R. W. (3. Davis, 'respirator la applied any devlites^fJer app ictlon to the respiratory organa of tha^^er. (eh kind (applying particularly to chnlcaT^a^ps) are offered for the guidance of those who areNffellfd equipment for vaztue ch*ical processes. c^i (April IS, 1939),(British) ,ce designed to afford uaea end llmitatloos of alned. Suggostlcns select and provide - 458 GASSHC ACCIDENTS. 3. S. Illkas and D. Hatheson. Chag k Ind. 38, 316-23, (April 13, 1939). (British). > Tha autbora, as lnepeetora of the Factory Dopartuat tt^ngland, have tabulated the reported gassing accidents that have occurred during <4TM poet six yoars. It Is shown that carbon monoxide produces far more accident^=gL any other gas, almost as many as all other* combined, other gasas encountered are hydrogen sulfide, sulfur dioxide, ehlorlno, nltroua fanes, ammonia, banzol and trichlsr- ethylano, to mantlon a few'. Accidents are classed aa those due to "expected" gasea and aa those due to "surprise" gases, and some of the most serious acci dents aro caused by the latter In locations where the gas is sot manufactured cr handled, but is generated or encountered by accident. It Is noted that chemical works do not. produce a high proportion of the accidents, and that most are in tha iron and steel trades, particularly the blast furnace and it* associated equipment. Lenghthy descriptions are given of certain general precautions to ba followed. References to Rocent Literature 6 459 KAR OASES AMD SnXSIBXAl HAZARDS IN THOR MANOTACTORE. H. N. Colt, J. 3. Driver, s. S. Bowen and 0. Cooper. Arch. Dezaat. A Syphilol., 39., 45*54 {January 1939)* The authors vara consultants in a factory in which dlphanylchloroarsina (DA), chloroacetophenone (CN), dlphenylaalae*cbleroar3lne (Of), dichlorethylsulfide (35 sustard gas), and phaayldlchlorarsine (atarsilta) were prepared which act* ad as irritants on tha sttns of workers who were exposed* The procautions and treatments in the use of each aro listed* In general, the authors suggest the following prophylactic measures: (1) absolute cleanliness in the plant; (2) change of work clothes every 2 days; (11 careful washing of hands and face bofore each meal; (4) bathe and change to strait clothes every night; (5) use gas masks in allvoperations where exposure ^^a^trous gases Is possible; (6) with all prodtrcw except mustard gas, t^e wtrang of rubbar gloves and a mustard suit* (7) hgjdiate treatment of a^ab affected by DA or IK with freah solutioostfif. sodium hkpochlord^L^ As^^sgpdcted by CK should be treated with 10&/f$tvx)d of sodium bicarbonate* " 460 THE DETECT! & lad., 58 The sense" aethod^Td^^et i^torrai atao sehJatrfe to very suitability of exist method for the detect! the Dept* of Scientific dote have referred to Times and ben2tne; all have AND VAPORS ZN INDUSTRY* S* Chao. 1939). (British). havlor of animals are bostf^uarttiable as general nco of traces of tpr^OTues encountered in many for simple, jmdds^ssmi-quantltative tests, of gaeg^S&ijvdpora 1* pointed out, end the 'roNdescription Is given of such a 'saame of which have boen published by search (England)* Those published to hydrogen cyanide, sulfur dlodde, nitre us these abstracts. 461 THE TOXICITT OF 0: (April 15, 1939) Acute 'and chro - vi ag by vapors^of o amples of pq not only n aan are givan^iThe 0 to high cone ontradons b exposures to low concentrations do much towards the applicatjj^f in- industry. ^ Chat, fc Ind. 56, 339*42, solvents are described and exhas been to stress the danger the lese frequently under* learor realization of these in the use of these sub- LORBCmiC DETOKINATION OF HEMOGLOBIN AS HJggftlED fiXN OR AS ACID EEMA- TIN, BASED ON MANY DCPHTBTAL-tfEDICAL BOARD SUKSCATI _ Himperdinck. Deutsch. Arch. f. kiln. Med., 183, 379*66, (Feb 1939). (Geznen)* In two-thirds of 400 samples of blood, the hsnoglo^fn^falues by Burker's hamo- globlnometar and the Zelss*Ikon homometer (add hemafin^were in agreement. Occasional add hatia values dlfferod greatly from wrtie^br Burker's method, probably beeause of wide variations in the course of fosndon of add hernatm. By Burker's method, absolute hemoglobin content per erythjslfee abowed very little variation in the 400 subjects. Of the total n\berp3fljt had 5 to 6.2 million erythrocytes per cu. 463 CHRONIC CARBON M01GXXSE POISONING AND FZSSXCICFOS ASB1IA. H. Biedezmann. Folia Haematol., 61,186-200 (1936). (Italian). A subject repeatedly expoeed to carbon nonoxide developed haatologlcal and . neurological symptou lsttatlnguisbable from those In pernicious anemia. Tho rapid regreesion of the neurological signs under therapy lead the author to re gard the signs of pernicious anemia as symptomatic consequences of tbs carbon nooodde poisoning, rather than as indicators of an independent primary perni cious anemia. It is suggested that sm apparently refraotory casee of pemi* clous anemia may be due to unsuspected, repeatod exposure to carbon monoxide. y Rafsrsncea to Roctat Literature - 7 464 MEEH3M IQS TBS DETECTION 0? T03XC GASES IN nffiUtfffif. 2D. 5. NITROUS FUMES. Dept. of Sci. % lad. Research, Great Britain. h. M. Stationary Office, London, 1939. Nitrous f\me* are usually reddish-brown la color and consist of a mixture of NO2 4. with possibly tracea of ID* Dangerous concentrations nay be en countered is many important Industries* They are also encountered in connection with electro-plating, engraving, natal cleaning and photogravure processes, are formed during osy-acetylane welding when the flue ploys on cold steel in a confined space* They hare caused fatalities during the heat treatment of metals in molten nitrates. Ia the test dsMrlbed, one of a series for use by unsttlled f personnel, the staple is a solution of a-naphthalene and sul_w^" id la acqtic add by sth^drd hand ptnp. The msber of strokes )btai] J se-plnk color determines the concentratl itecti part in 100,000 (0*03 mg./l). Detail preparations of the reagents and ssa; hods are 469 AXHT IN CARBON 1DNQ2DX FOlWOTtfT ? E* Hsii and 92 (1938). a two casea of wrsMjtt&2> carbon monori.de polson- ch dlWwjkd ivo leaioas dsjHfihSjd^ Ao*Pr cerebral substance--lmmti 1 on doscrjwPj^SB are the basal lesions, of special interest ie^ttJi'abse blleir^Sltsehftaning of the globus pallldus in these casea since pethognooonlc of acute carbon non oxide poisoning. Aft lesions ccnonly found and reported, the authors discuss the . er which here been preeented to explain their development. They ^^Lenoncluslon that no single theory seems to be adequate to entXM^s^the action, of this gas on tissue cells, and that probably rs-ect '"togirbher. Anoxeala, specific vascular disturbances, and monazStonlcd^Thtitor uliar blood supply in specific parts of the b^&arvtlculorly in the b are hollered to act together in producing xM^pSteloglcal loslons found* 'AH0K3 ON THE POSSIBLE 07 CSTAIN 07 THE CHLCR- CARBONS WITH SOTGESTIOIB 70 NCBfERATIQNS IN TEE air C. r* Drinker. J. Ind. ay* 21, 195-9 (May 1939). erl&ents on the todcity of these ccmpo x continued end are report- cd in the p. a.per. It is vail down that a dl>^9)' ch is effective in preventing acute atrophy of the liver from exposure to'^gften tetrachloride. Tc discover whether calel\a in the diet would protefrf^gainat liver damage from a toxic chlorinated hydrocarbon, two groups of rattier? fed diets of high and lew calclia respectively, and subjected to inhalation high concentrations of a mixture of pasta and haxachlonaphthalenaa* It was ^uAtt_that a high calcima diet has no protective effect against the characterisw^liver lesions caused by these compounds. To check a supposition that xanthine l^paSlons reduced the toxicity of these compounds, another series of animals was^fcpoeed to the vapors, and part of thmm ware given xanthine in addition* So differences in the effects were noted. That the chlorinated hydrocarbons are broken up within the body was proven by a significant increase in the urinary chloride following inhalation of the compounds. Included In the paper Is a list cf 19 of the im portant compounds of this series showing permissible limits of thass substances In air. Most of them contain from 43 to 68 chlorine; the limit of all with but three exceptions. Is .0*3 mg. per cu. mater of air. The exceptions are: trlchlcr naphthalene plus a trace of tetrachlornaphthaleiie -- 10.0 mg* per cu. a.; chlor inated diphenyl -- 10.0 mg* per cu* a.; and tetra and pehtachloraaphthalenes -- 1*0 mg* par cu. m* ' ; :: ` ' ' ' References to Bscsnt literature - 8 467 TOXIC sncris upon RABBITS OT PBRACBLOBPBSOL AND SOdtH PSflACBLQRPSENOL. H. A. Echo*, F- Deicimann-Gruebler and . 7. Xitmlller. J. lad. Iftrg, t Toj^col., 21. 160.72 (Mar 1939). . Pentachlorphenol la used ea*rcially u a preservative for wood and mod pro* duets. Sine* annual hand!1ng of treated lumber cannot ba completely avoided, experiments on the material were carried out to check the reported to^c proper ties of.the material. Tits substance whan dissolved is capable of penetrating tbs skin surfaces and tbs Investigations <Mni aad* with this In Bind. Pentachlor- -phenejfias well as Its sodlua aal>^iMy?ob sorbed Into the tissues {cutaneoualj or ipooittaneoualyJ in sufficient q^fitlty, produces an acuta toxmala. The dose^nplled cutdfi&iuaiy7 variad, dapending on tha solvent, 39 ag.'ipfirttlc ^ it (In pins oil) to 390 ag. per kg. oU). Ahpfelft noi [tally usually recovored fully within^jJCsjJA 'short periods [di cat ion that tbs absorption of rapa^ilkll doses induced a aJ 9lsoiling. It- is stated, however-^n^^ms latter point needs (ion and for this reason tbs aavrtpirAhould be em- ployed ell 468 of DUHYAxlvsaT^f^-Eaug, S. 0. Calvary, 3.J. 0. We . h To^coRgjjly 173-hOl. (Soy 1939). ^excellent paper ,ta ugh b^TVto^&T the literature and report* on an extensive series of compounds in determining their toxldtles. Over 2600 tbs taste sad tbs methods of statls- tleal analyses employed .teresting. After oorrelatlng the in formation in the literature respite of tba experiments, It is concluded that ethylene glycol, di ycol^Mtqrlsa* glycol mono-etbyl-ether, di ethylene glycol mono, . add dlocuC^bould be entirely emitted from food aad drug propylene should be avoided except in very snail concentre' FATS OF IN THE 0 tt sad J. H. Johnston. J. , 127*. 769-TO (March 193' 1c add was identified in t which repeatedly inhaled doses of trlchlorethylea*. it as a conjugated pro- r may possibly be e decomposition seme^mtr* complex unstable ,---und actually excreted. Thera are Indies^------th--a--i-t^r^t--th., same material is pre- seat.in the.urine of hiaans axposod to trlchlorethyleae.^y 470 TRICELQREEESLBIS DBSXASnO TAMS ABD THEZ3 SAFE OFt^ttlOH. W. B. Harris, C. B. ,Ford, F. A* Patty aad T. Hatch- Indust. Bull., I. t^tvee Dapt. of Labor, 19 132-4 (March 193>. . This paper give# the results of a survey of 90 plants uttnjRtrichlorethylene degreasing tanks, with a detailed survey of IS of these stored. Becoanandatlcaa are aide for the design of equipment, location of equipunto^ocal exhaust ven tilation, and operation- Dimensions of tank and room, quantity of flo* and rat# of flow for adequate ventilation are gives- The exhaust ventilation should be applied laterally at tha edges of the tank sines the heavy vapor tends to roll over tha edge end fall to the floor. A ventilating rate of 60 e.f.m. per foot of tank perimeter has been found to be adequate- This produce* an air movement of approximately 20 f.p.m- toward tha exhaust openings et a distance of one foot from the slot- It la necessary to keep the rat* of air flow aa low as poealble to maintain effloltncy of control and to prevent too large leases of the sol -vent- ' - References to Recent literature . 9 71 CTntACHLORgTHgJIg IK TBS TREA3K2KT OT SDQCHOac DISEASE WITH SPECIAL RZTBRENCE TO ITS TWOCITT. P. B. Fernando, K. daSilva, 0, g. 8. Stork tad G. R. Sinna- taaby. Indio J. Hod. Res., 26, 759-63 (January 1939). (India). Tetrachlorethylene, studied la 111 patients, u found to be effective la expell ing hoolonxma; a single dose of 8 cc.for adults will expel lOOjt (as many as 310 worms) but has little offset on roundworms. Cartful examination of sack patient was made la order to check the toxicity. Several llTer tests were employed. Ho appreciable toxic effect on the liver was noted la any of ttm even in those re ceiving double the maximum adult general use. Ho depressant effects of any importance were noted and so teoSUction on the kidneys. There was occa- siaaafngiddineaa^ faintness and wetness but these were only temporary. A of 86^cd*>~^4lsa tha^Oet effectjfS^ bur^one of 4-5 cc. can be given to adultj intervigT of lO'; eta on children are also discussed. 72 _____ )RXSE POISONING IN TBS CAT. U. WCTS. H. L. Stewart and A. Cantaruw Path. ,26' ^ot of first article in this s e So. 758, 1938. tih 44 cats, divided into The first re- irochlorlde per kg; econd group, one or acre The s group >th groups were s 'dance of damage liver were le dose of .ftere: divldod. Two weeks trachlorlde ns Group I. Cats als and the changes noted. second group In the first 6 days after carbon tetrachlorl were essentially normal The end of 6 days, the Group U livers igns of extensive reeidual damage in those of Group I. Also ab iliruhinsmia, retention of brcmsulpha- leln and uroblllnurla ____ :ad ';ik ee with ligation of ducts. 73 COMPARATIVE ACTION QFXN&AXD COMMERCIAL ON TBS VASOMOTOR SYSTEM :? ANESTHETIZED D0GS3 \Rjharlior and Ph Angeigt,,, Ccmpt. Rand 3oc. biol,, 130, 779-62 (1939U ^Mgrpnch) NEW RZSEABCoat IBS TOXICITY OP ^ R. Arch. Intern de Pharmacol. _f 123-53 (Pebruary 1939)*%4P*enc describe Dautrabando* a work am;t)M cal effect of "trystal- `canerclal benzene" on the centrel^v^ous the peripheral reso- Ltd*' system and the ^rocardium, and presontJtfii_re__ f similar resoarch on ;) the toAcologlcal effect of chemically pure^oenze ) a comparison of tho effect of commercially and of chemically pure benhna, (3) the origin of the greater toxicological effect of comercially pure~$pe Sxparlments conducted on three organa (heart, intestines, and vascmtoottoor mts showed ccnercinlly pure benzene to have a greater toxicity than chsmic e benzene. Research wan than conducted to detezmlne the compounds which this result. Ecllow- ing the fractionation of commercially pure benzene into rtant groups, it was found that the fraction boiling from 80.4 to 81.2C. .test tczxoit7, greater than pure benzene itself, Further studios of this Tuution and of the impurities in the substance are to be undertaken later. 74 SOLPTOETTZD HZDROGBf raODCJOT BY BACTERIA IK A LEAD KINS. J. W. Sdington. J. Hygiene, 30, 683-7 (November 1936). (British). Soartlng eyes, markedly congested conjunctivas, and a stinging sensation in the note and throat were found in 12 workers In a lead mine. The strong smell of hydrogen sulfide In the part of the mine where they worked was traced to the stagnant mine water in which there were sulfur deposits. Samples of the water yielded great mabers of bacteria. Improved ventilation eliminated the trouble some gas. Rafarene** to Recent Literature - 10 473 auralCATIONS ST B2NZEKES. K. Duroir end H. DesolUe. Preaee aed. pp 331-2 (Kerch 1, 1939). (french)* . Acute intod.cations, usually by accidental exposure to large concentrations of vapors, cause the ease injury as do other lipoid solvents. The first symptoms are inebriation and too!ting but those disappear rapidly in fresh air. A sore - severe form causes loss of consciousness or heart failure end death. In chronic poisoning only the aromatic hydrocarbons of the benzene ring cause blood distur bances. Impurities play a moll role and. benzine does not seen to attach the blood. Methods of treattaent and pronfawlajls are given. If exposure cannot be prevented by enclosure of the processor adequate ventilation, some other sub* stance should be mployed. Us^uNHa french Society of Hematologists ref ae^dad) that where they are not isflfpensabl*, benzenes must bs prohibited 475 he suffered again fell. This * the slightest uvmsnt.1 and the man died 6 hours the chest). BRZA^OC HXEROGBf SUL7IDZ GASES ^ , 1149 (1936). (German). sulfide gas the patient lnhalwOwfi'er small others in the laboratory mne!Saqta.7 exposed, patient hind a dizzy spell {a^sutfered chest eonirritation of the >at, cough, weak and lrregse bronchitis, ddjurapf, too!ting. The next me and thohida^Ku^r ms 124 ag.%. So wns days, jl$a|f3rling orders and actively aoving eat pelns and the blood pressure fever end angina pains ware fait at jlcfet^pdtaant the condition became aggravated pectoris (severe constricting pain in 477 EARLY DLli2BSIS Of TTchnschr., 65, 3: (Guzman). In examining rkers the aOSbor arsenic ab arsenic polsosrfg. only hyMCLMMolfls any be considerredjSfc'' a prosgd%jawry pearls, that can be fUgtftn&hltravlolet light. Is characte, 3KOO. G. Streube. Deutsch. med. spted to distinguish between Levee that those cases stowing Lfrcm arsenic -absorption. The >an early stag* by the use of itter. EtmuKorrs oh lcno changes Arm inS&ijsi $(g$^NHALATioH. s. Ropioh. beitsachutz, pp 144-4 (1939). (German). ^ _ The author, lsvestlgating the pneumonia producing^rop^ki^es of manganese, had rabbits and mice inhale dust containing 90)6 insngrtgyrt dio^de. Of 32 animals, 9 died within the first 19 days, all of which showtd^borw or Isss pronounced bronchopnetaonia. Of the survivors seme were InfeotedT|ntrwnasally with pneusccoccl and half of tham exposed to drafts and cold. Btttd$fcree of those infected survived, and It was In these that the lung changes foind^f*'* most pronounced; those dusted only had no lung change*. Since Thomas slag~|a4ucea pneumonia m man also, a dust, containing 10% manganese diozlde to slmufSpw the slag dust, ms used la continued experiments. About the imt results were obtained, neaely, that those infected with pneumococci showed setare lung ohaagoa, that in those not infected the lung changes were not so marked. The author believes that the pneumonia caused by Thomas slag can possibly bs traced to the manganese dioxide. 479 MOTES OH WHOM} WITH BRONZE FOWIHRS. K. Derlbere. Ana. d'Sbrg. Puh* Indust. eu et Swouovt. 1406^, Sww0v4*-7f . (\ 1936). (sfr*ewnmcwhm/). Bronze powders, which are composed of salts of oopper, are used in several In dustrial processes. The workers, under the impression that these powders are poisonous, tend to ascribe any sickness they experience to this cause. Largs does* of copper solts are indeod poisonous; but such doses seldom, if ever, occur Industrially. Tha copper salts gr* rapidly eliminated and do not set up a chronic poisoning within tha body. 'References Recsnt literature - 11 aeo vsnoaum 07 JUnRXSSS. a* 0. Oettlar asd L. ZLlerbrook. Ai. 1. Med. 3el 197. 685-37 (Kay 1939). The methods of detection tad quantitative determination of fluorine la body tissues ere explained la detail aad the aomal coatoat of fluorlaa la many of the organa la llstad with both, raluas from tho literature aad thosa found by tho authors. Very "--1} amounts of fluorlaa ore found la nomal tissues (20 to 80 slcrograaa la 100 grass) and there seoss to be no appreciable accusu- latloa of fluorlaa la any oaa of the vital organs. The fluorlaa content of taoth aad bones is higher, being of the order of 0.01 to 0*0356, which probably varies with the mount of fluorlaa ^jjlhe dally diet. The sysptoas of fluorine polsoj^ng are reviewed and aa ateflpt*Ta made to estimate the alnlmva lethal ingest! loa Is given to the inhalation of t 481 CSB0HXCx FROM THE R033TOB10CICAl STAt Holler. 12, 13-20 (January 1939). (Britis Chronic fl in oaa was discovered la 1931 ithor was in- vestlgatlng ctory werkora aad case upon c sos In the bones of i la a cryolite factory can recognized in nnImalsrelhaftae that the symptoms in ) the cter aad Included lack of nausea, a the individual want into 'open air. It apparent tolerance to the dusts following eoatl clpal alga of fluorine poisoning Is la bona changes, a bones. la the affected lndlvid- uals, there was almost ooxmal body structure, the boaaa of the vertebrae milky white opacity. In the extremities, the eoopac t thickened aad the narrow car- itlea narrowed. The after 2 1/2 years of exposure; sore extensive c ears. Another feature of the condition concg^ th^teeth ^scribed as settled tseth, have baea roc ' tated that because the occur- ranee as^ro sents a real lust problem, Work ^ _ phosphorite and calWAj should, la particular, be extrme caution. It is. ixportan^ logists recognize tho in of fluorine poisoning, and cart * " sis nre given in the INDU3TRIA1 CHLORXNI GAS POISONS. X. Schulze. . _ ergiftsf., 10, 1-2 (January 1939). (Oemon). - A warkar la a mail ahmlcal plant was exposed to <$ntorine gas during the course of an experiment. Although he had broathed only a maVV amount of the gas, he had to be helped frt* the room and then loet consclousheAs^ At the hospital he developed en acute, severe bronchitis, aad about 3 waewfTistter this seeoed cured but It agalA developed a few weeks later. The bronchitl^ge^ste chronic and tho patient was troubled with a& increasingly severe cough end^&pnee. Respiratory functions were badly disturbed; vital oapaelty was only lOOQr'cc. and respiratory minute volune was almost double the noxsnl. The case Is \musual in that son- fatal cases usually do not lead to this chronic condition. ).483 UNION CONFERS! ON L2AD POXSQKdO. Labor Stasiaxda, t, 98-0. (Aprtl-Uay 1939 The control of lead poisoning was discussed by tho Battery Cornell of the Uhlted Electrical, Radio and Machine Workers of America at a meeting in Phila delphia on March 19. An outcome of the meeting was the appointment of standing camlttees to gather detailed Information and to conduct further conferences ca the subject of occupational diseases. References to Recent Literature - 12 464 THE EARLY DIAGNOSIS 0? ACUTE AND LATZOT FUMBI3C. T._ L. Salth, 2uXt T. K. Hathwell and a. E. Mereil. Am. J*. Clin. Path., 8 , 471-508TI936). Reprints obtainable from the senior author, Jeffarson Medical Collage Hospital, Philadel phia, Pa. The many symptoms that may be found in lead poisoning are listed and mention Is made of the difference in susceptibility to lead. The authors review figures given as normal lead in urine and concentrations In urine of exposed end poisoned persons* In discussing the significance of stippled colls, the authors list six A teen other pathological conditlona i^ahich these colls hare teen reported. In ^ therjtbor's series and experimendfiretappling did not precede symptoms and * the toxl $ag^" Reticulocyte response and basophlli< .dered te as diagnostic tests. Detailed blo< ' fcats grouped according to clinical a differential diagnosis can be made<S3A*%ate cells and fibrin fraction whan fftjqisSrered in re- alue. Tbolr analytic method is gCbeJB^In normal sub dally changes, had no affect 'q^WSole blood Talues, t exercise* It Is sitfQWcant that, In normal in the sona, b^n^ns of plwbla, sera In chronic poisoning, end values are higher than et, lead will reappear In the 465 THE CLINICAL SiaOTICANCE Ana. Int. Med., 12, 1429 The mean number of rtlppJ^^dMh^syte red cells; in 234 patlM&^rlth ddfMren million, five patferattsw to whom lead^was after symptoms a^xn, but 2250 up to^the exposed to lffi&>bjprrree of symptoms .^hostl tratioa a^3aigftne hmtatln to 2 patle 5250 t^T^32. These data suggest that dlKiaQ*e? either lead absorption or lee Hi THE 3&3TS&0C7TZ.S.S. Talconer. normal adults was 92 per millioa condltloas, it was 363 per stared, had 19,950 per milliba toms appeared. In 8 workers was 2100. Adainisstlppled cell counts of a is not a specific in- RB2ZNSRATX0H IS EXPHUKTCAL LEAD PO: SOLUBLE UVTO ?AC- If. Lauro, 0* S* deSacy and A. Artbus, et blol*, 130. 642-4 (1939). (Trench). A brief report of experiments on 35 rabbits given's^dlffc'orent liver extracts after amnia induced by lead. Regeneration of bloodrogaa within 3 to 8 days after intravenous Injection of the extract and reached^^fairly high but sub normal level. Control animals given no extract recovar^&ly slightly. Regen eration took place regardless of animal1 a age, duretlon o^siataastf amount of lead injected, gravity of amnia and time of liver injection^) -JP 467 INFLUWCE OT ACID AKD AISALINE DIETS OH P0RPS8XNURIA IH BCPSaMWEAL LEAD POI SONING. A. Capellini. Med. del Lavoro, 30, 33-43, (1939). (ItaUan). Three rabbits on an add diet and three on an alkaline one were given 30 cc* of 3% solution of lsed acetate dally for 30 days* Porphyrins in a 24 hr. urine sample of the animals on an alkaline diet was 90, S3 and 106 mlorograms. The corresponding figures for the animals on acid dleta ware 187, 136 and 132, but in these latter, the. porphyrinuria dropped more quickly when the lead was dis continued. References to Recent Literature - 13 488 LEAD POISOKDC, LEAD COWTEHr OF BLOOD AMD OF EGREIA. 3. L. Tcmpsett end A. B. Anderson. Lancet, pp. 359-62 (March U, 1939). (British). 5 'l Tha lead oontent of blood and excreta of 29 cues of suspected lead poisoning was determined by the sodium diath/ldithioeerbonate method, certain Improvements In which are stated in detail. The Investigation confirmed the opinion that the ostiaatioa of blood-lead is acre satisfactory than the determination of the ex cretion of lead. The upper limit of normality for blood lead is placed as 100 aicrogrems of lead per 100 ml. Then this limit is exceeded, or if there is a total daily excretion of 1 mg. or mojrf?of lead, thaa lead poisoning Is present. Details are given of a large mafcamjSjtJ^eterminations mado* The concontratlot of to the blood of these cten to twenty times that la the url; Nevttfcjmless, it/unaot yatdn, clamed that the eJMOlcal diagnosis of le soniagdFfpinfallible, e^em \ho4gh it is surer than clinical methods. 489 1 1H 1939). ( Lead can be eery solutinnvvn)px c ac >, formation ol nitrate pr^etiitat long and verys star-ahaped bundlaa. sanca of 60-70 parte bl tin, silver, platiniM earth groups do city may be increased ab; lead oxide on the platl about 1:40,000. C. Kahr. Mlkrochcm., presence of other heavy: formation of clfic lead thiourea nit the lead-containing 10 voluu of solid is added. After di t&ls is observed al eraseope. The lead ^doubly re: jedlalike prims, 20-50 mi- "Lee crossed and frequently united in lead can be detected in the pre- more than 100-of cadmium, arsenic. The metals of the ammonium sulfide and similar concentrations. The spocifl- s by^iApreviou* separation of the lead as tdde. '-Th^ilaltlng concentration of lead is 490 PAHtnOT PR C. D. Bridges. 44-7, (Kay 1939). There td?ferent type# of pL___, by mmerous firms, and ingredients are used that tx/ to determlna tbs toxicity s. The safest practice is autions possible when type of paint or lacquer, , exhaust booths are le ahare it is possible to employ tba^^A tlon is given of the mental principals of axhaust booth construction, exhaust ventilation is not applicable, respiratore should be eoracTbay be supplied air res pirators, u this typ is more efficient and mor#jenmfortle for continued wear, and the air supply is convenient. The air line sltf&be passed through a filter to remora fiaes, dust, moisture, etc. It should tie rMgiTunil that dust respir ators do not protect against fuss a. Paint daxmatoseiirdpe to allergy to ths var ied Ingredients, may be controlled by protective cloth^g^and the use of pro tective skin rrsems such as vasoline and cold orwm, and nMtintlng the use of solvents for mashing. Paint brushing involves expeeura/tos4^ solvents and re quires, primarily, good ventilation. ^ 491 MEPICnUBAL COKPLICAITOIIS TS 0ZRCAT0L0G; CAUSED BT KASSACSTSETTS KOIKKEN'S xnFQQAT1GK Ad. J.H. Blaisdell. Arch. Dermatol, fc Syphllol., 39 . 69-80 (January 1939). The author showa that the question of cnpensatlon Is lsrgaly dependent on the Interpretation which, since the enactment of the compensation oot, has become evolved through practical experience. Ha streaeea the difficulties that srise for the dermatologist in testifying before a group of lay referees because tf the impossibility of always giving a definite *Tss" or "86* answer. He gives consideration to the use of patch tests in cvldenca before the referee*. Follow ing these discussions are several suggestions for changes in ths present law. References to Recent literature - 14 498 CQZAHBXS XBDFTZ0M3 AMDS IHDCSXRIA& HORSKS. J. 0. Downing. Arc*, Deimat. Syphilol., , 12-38 (January 1939). The author jwmti a largo sail of Important data relative to industrial derma toses, taken from a study of 2000 eases. He has aaay tables which bear careful study by those interested 1b the subject. Prevention and ilag^sis of dermato sis coses are much cheaper than neglect. A process should not be condemned as dangerous because one or a few workers are peculiarly sensitive. The largest number of coses occurred la young untrained workers between the egos of 20 and 25 and the hands were the most frequently involved area of the body. There is an Interesting discussion of the d^ntMhutlon of dermatoses according to occupa- tlo&St/wnd there ore excellent luukirof important contacts, materials us and trancteriftia\effscte ljuAhe Afferent occupations. In discussing prjjv tloa njprtweaes^fcM Inpos^mcsuof detoctlng end eliminating hazards tance oMe^hnalo^4sgjOffi\ Importance of gloves, and protoctlv and creastoj/^The little value In pre-employment patch^J f'ha dis cusses theN^xe^T^S^ proper evaluation of the tests as tmj^rg occupa tional expo ' 493 R. Joerster and ^^h. Darken Syphilol., 39, nflfcfc^ftnuary 1939). examined,808 mawtactorlas usln^^tc^aad tar products. Moat of thfOpztoneous leelons^qn^rve^we found jU^Mnrs who handled pitch or pitch products and who were dsljx thdwAdk gragqmt Patch tests wore performed on 14 pitch markers and 4 oiaiml shb^Mtf^LtT^tha dlffarent fractions of the pltoh and tart and the ar^u^ahujL^m^^7* exposed to radiation of various wavelengths. Same of the osp^gilg3Kr|w chemical and physical properties of the pitch are discussed in detjdraKMm thel^sstudies, the authors conclude that pitch dermatitis and <|smsr1jj1iif tTr Sfhd^cts of true photoaensltlzatloa and not of allergic ansintesqljm or prasUspoettl^n. This photoseasltl2atlon occurs through local ixopCMfasmotlvlty1 ofa' spectfjc^photosenaltlzer. The tests rt- vealod that noA fmgsdi^Tar fraction of^the pitchy'or distillate of the tar can be pri? the production of.jpfioto ration. The most important _ b in the range of blue'sh^vi visible light and in the ha of ultraviolet light ( ms). The aost active c hydrocarbon in pitch, namely; which has fluorescent 2500 and 3800 Angstroms, is prob on*~4\th* photosensitizing ante. OIL DERMATITIS. Anonymous. Safety 77, 49-S0 (lta^2939) The article reports on are researches carried out^k^dematltls from cutting oils, about which the following conclusions are draSw^The oil itself is not the direct cause of the shin irritation; rather It lSN^Wdust and bacteria fer which the oil forms a suitable vehicle. The bacteria a^jrWt from the oil, but are on the attni all cutting oils are capable of penetrutZDg^Che shin surfaces and the bacteria enter by thia means. These bacteria oleo^aid entry to the skin through minute, cuts made by metalUo particles in suspefijion In the oils. Prevention Is best accomplished by thorough cleanliness. The'offected ports should be washed twice a day la soap and water and no oils or gasoline should be used to raovi dirt. 495 AIXALI BCZZKA, ITS DTTttOHflWT AMD FRZTBfQOH, HTH SPECIAL RETStESCX TO 1CCERN SOAPS (FRACtTEAM, SASXSA). H.f.Sehreus. Med. Telt., 13, 222-5, (1939). (German). The author considers that usually la hyperssaeltlvlty to alkallss, no real oiler glo hyperseasltlTlty Is present, but an lamellate sensitivity brought on by chon leal and pfayslco-cbMleal reactions. Only prolonged contacts are Invariably affective. Since eczemas are only exacerbated by aTIfline soaps, special alkali-free soaps suoh as "Praeuton" ere recommended. References to Rseeat Llterature - IS 496 CHRONIC GBAHGLQKA DC INDUSTRIAL DB&CAIOLOGT* 2. X. Killer. Arch. Dezsat. fc Syphllol., 39, 33-44 (January 1939)* la 3000 patients axnrn-jned for tha industrial responsibility of tbsir aruptloa tbs author fond 2$ with chronic grsnulcmata of which 16 wars syphilis, 9 were cutansous tuberculosis, 1 blastomycoais, 1 actinomycosis, sad 3 wore leprosy. The role which each plays la these cases is discussed briefly. When chancres develop la the sites of industrial injuries, the carrier of insurance mist pro vide treatment. The localization of lealona of secondary syphilis is rarely in fluenced by trauma, but the lesions of late and latent syphilis suy often local ize oa the sites of injury aad will therefore be important la the evaluation of industrial dezmatoses. Millar warns^fcyilclans diagnosing and treating iadus- trialxdeimetoses to be oa the lo^&tJSr tuberculous ehaaeros since he beliei tb^^^ldeace will rise iajyu^ fu^e due to the definite decrease in earl] aoi - - - -- 497 SOUS C $7 TBS IMDUgffllAL DEKATOSE. S. X. May 1939)* records will provide a means foj ing the inci- aad relate such lndi^snihr7'occupations or examinations euiA maCr to afford an oppor- to reaction type adg^rapAe the physician to ed- discussee'\fony^Sf the important practical rfcars wha^wScdnely to be exposed to dazmato- 498 DWATITIS IROM COTXSXC ACID. 8* M. Watrous. X* Am* Med. Assoc., 112. 2132 * Hicotlnio acid has been rei ccmparatlrsly Inert substance aside fm its specific eff Patients hare, however, noticed a sensation of t following oral or Intravenous ad- ministration* e, c rtories are presented ahieh indicate that nicotinl capable of produc at dexaatltis in certain persons nicotinic acl^jhblet the course of thair naaufac- ture. ^n^_gay all of the 4 cases pr^een affected porta of the shin had of a mild sunburn and itohlag sensation, cases tha condition subal n s= c^or two. Only a small pro n of the workers experienced these le ASEPTIC HBCROSXS OP BOMB. I. INFARCTION OP'^OS ST^SSOM DISEASE RESULTING IK EB0AF5QLATSD AMD CA1CI7IXD AREAS IH EUAFECfSIS JND nQfcrfflXTIS DXFOMtANS. S. C. Eahlstrcm, C, C. Burton, and D. B. Ph^dr^er^Surg., Qyn., h Obat., 68. 129-46 (Pehruary 1939). * Caisson disease (compressed air disease) is tbs reiplt-of tissue Injury caused by altrogmi which comes eut of solution In the blood^jAbody fluids in the form of bubbles following' too rapid deco^resslon after exposure to increased pressure Because of the greater solubility of nltrogsn in fats, b^gy-tltsues with a high fst contest are sitae of predilection for bubble foxmstlQfiS)Tfca tendency for bubble formation to oocur in the spinal cord, the nerves, a&i the subcutaneous tissue is thus explained aad has often been deeorlbed* However, with the ex ception of a single case, reported In 1088, there Is no report on tha patholog ical findings in the bones aad joints in caisson disease. The present paper deserlbea 4 cases of compressed sir Hisses la which extensive bone and joint ohangss are fotmd* The coses are wall presented, with complete case histories, z-rey and autopsy material, aad illustrations* Zt is not improbable that as a result of the fladi^s, bone sad joist changes attributable to this disease will come to be regarded as a appeasable occupational disease, aad sore attention will be paid to the prevention and early treauaent of the condition. Reference* to Rsusat Literature - 16 900 CGMFBESSBAXR DZSZASZ ZK BOHDim TEZ BSC8 AI7TO ROAD "SAmSRBaS-WZSDBl" AT TBS aotTEHBN TABQSrr Of TBS BZ8LXM RUO. 8* Konlf* Munch* nod* Ichnschr., 66. 370*3 (1939)* (Oexaaa)* The author* e* pome pent medical supervisor of the compressed air eoxfc which reached a depth of 30 meters water gage, wu always present during construction* Be presents three interesting case histories and goneral data on the symptoms observed. It is of interest that in reconpresaion* improvement took place at 2 to 3 maters water gage* 301 OH ST TBS inhalation or HELIUM Aim. K. Boothby.. Proo. Staff Meetings ^ \ of airplane pilots end flight. This Is duo tog^LJ^cS- to tend to rims 1 n nrmrpm unless measures are eojfew^to open it pressure in tuPmi^Ke ear* It has hsllia-oaygsa mlrtygqa pwftnt or greatly di nes equipped with inmarked changes in 302 DmrVUJUAL VARIATIONS V. Matthews* V* 1-24 (Septober Individuals differ high altitude characteristics and 44* habituated blood oxygen cansewy^tow alveoldr-oiygen o^dde pressuM^Siocpftgh alkaline reserve* at matlsatlovmmugiraltituda* It is '* nuaber jaf^Mr^ty trained observers gl i acclimatization than any TO HX<& ALSITOBf. A* HeySt 1*H* Proc* Boy* Soot 126* Series B, adjust to the rarefied air of related to a saber of mensurable normal men between the egos of 29 t youth* alow pulse* low-noxmal high alvoolar-carbon di al are favorable for acelicareful observation over a cation as to relative yet devised. [ON TO TEH KEEAHXai OP ADAPTASlOfe^THFgBMtfiiai TO BIOS T2KF3A- ^ Shaxovatova. Bull. Biol* et Ma&^m. 6^ 671-4* (1936). '(Pussies) ^_ Single or repetitive exposure of dogs to beat' (30$$)deceMbed gastric secretion in response to a particular food stimulus, and InrfryS^d the organ!o component* of the Jules; the laorganlo components remained practically unchanged* The ob served changes indicate the participation of both the^osGpe-reflex and neuro chemical regulating systems. 304 HZAT 3EBC0 AND iXXXB OCK&mORS. T. B. Nloholls. X. Bo^jfcqr Mod. Corp.* 72* 73-64 (Pehruaxy 1939). (British). ^ A review of the subject* written espeololly for army man in the tropics. The use of salt la the author's group reduced heat stroke to zero. 305 OBSERATZOn ON TBE BLOOD Of BFOSSD TO BXQB T9IFBAZ0BXS. P.L. McLain and 1.3. Montgomery* X. dim. Invest*, 17, 417-22 (1998). Observations on a control group of 43 worksrs la hot industries and 30 patients admitted to a hospital for heat ynpt<me. In the latter group there were 17 cases of boat snaps* 6 of heat exhaustion and 7 of heat retention (stroke"). Careful hlood tests were modes in the controls there was da^dratlon sad fall of blood sugur following work; in the patients, tbs changes depended on the type of beet ailment involved. References to Recant Literature - 17 906 BSATBO AJ nHOlATZHC STSTHtS fOR PHYSICAL CORfOHT. A* Hlndley. J. Inst. Seat. 4 7ttt. Rngn . London., , 36-42 (March 1939). (British). In this short paper tho author gives s aoimd sad Interesting discussion of teatlac sad ventilating tyitosi la relation to hieMn comfort. 3s regards ss tho main esssmtlels*(for sedeataxy arkers In Crsst Britain), a tperature of 64 to 680?.; a moderate relative bimidity, dean air, and adequate air movement; hs later refers to tte deelrablllty of variable air currants rather than a uniform and monotonous rate of aovaent. Tha>eutbor concludes that, In Great Britain* except for certain industrial purposwl air conditioning is overrated, and that tte air washer and refrigerator nLdp9 dispensed with, subetitutiag for vej lettnk purposes only a lergejroI\ttJ of fresh air and making provision fo; olr aovahaat to b*4SsSl esrequired. 907 OecoBhei Over 7600" during 1931 sent for/tf'ftWf'ar mol mabo^l&{bb^^>ln prwv< it vieorsj various operations appllsacts are glvi Sane Office, factory Depertme .were reported to the factory I Groat Britain lents reported are probably causing disable- total nushar of eye ac te'Tb not 2ao*n but this >rhood of 100, The losflet deals with and portable), halnots, to, and the requirement! for the maintenance of protoetive 906 CBDCCCAL 10SCLX CHARMS' :c TRAIHA. 0. Hostsmartini. folia mod., 17, 7S46 (1939). In animals experiment: finds dsnlseralisatlj or a with an alactrlo current, the author , and alteration in calcium, sags#* slim, and potass* Thai urn to normal, however, sons time after tho end :n>to electricity Bf PCS! 6. Allsop and R. 7. Instil. Kin. (fabruory 1939) (British), :s have dearly established t mixtures can aaslly be the rubbing of blunt picks or' against pyrites, and it >ught that the mechanist of the lgnl Lows. Under the rubbing itton, some of the pyrlte is reduced to hated to between 200 and 300C. Within this range of taper^ on of the powdered pyrlto proceeds rapidly and ultimately flam (b sulfur) appears. This flume Ignltea the firedamp 310 Docauans or OCCOEF4XXQHAL ANTHRAX. Med. du travail, ~ 46-66 (1939). (french), french rula regarding compensation of anthrax as a .tloaal disease and Its former compensation as a accident, are reproduced soussed. Instrue- tloas for the prevention of the disease ere also lnd _ autter reports on two cats treated with sera and with fomentations of segtopllx (paramino- phanll-sulfamid). He ala mentions eight other cases treated by Kurteanu and Zeltaaa with other eulfamide. 911 P90FBSAZI6 Of MOWS* AOTLOOTOMIASXS ZH THX LOOT 7AZXX7. C. Garin and B. Roman. Ann. d'hyg. pub. lnd. too., pp. 96-66 (februaiy 1999). (french) Infranee, miners* antylostcmiasls (ala called miners* anemia or tunnel anal a) is a compensable disease. It can be prevented by keeping the mines as free as possible of worm larvae and by examining and treating the arkers. An intensive Reference* to Ractnt Literature - 18 effort waa mad# la two mines employing 4900 man. The percentage of lafaatad qen, axylng widely from pit to pit, wa* fouad to range frcm 16)6 to 69)6. of the la* fostod worker* treated with tetrachlorotlylena, 60 vara entirely freed of para* altos; cbenopodium oil aad thywol vara not more than 90)6 offoctive aad quinacrlne was useless. final examination stowed the Infestation to have droppad markedly la all group* although it bad ut baaa completely wlpad out. 512 WEIL'S DISEASE IN COAL MEMOS. V, X. SffM. 3rlt. Nad, ?*, pp. 603-9 (March 25, 1939} IZ. CLINICAL PACTJLOOr. A^SiSladden. Ibid* pp. 603-7. (British). Tba prevalence of Vail* a disease iEfuxwfier ibova by tba tlx casaa roportad aacng^5otah Valaa <coel alaara^. Th^aymptoma vara typical; Jatmdice, oai and vu^A^oBAat^^NganandiS^muacular pain*. Oaa of tba eaaaa vma diagaoetirwn# varlgadjjt^Stca^ccaa by aarologlcal investigation and agglutiniw^stf raact^rxo^iptoaplra. Laboratory lnveatigation*<^p4jiM*''Gut in. table* i mTiii iTOjinaiai nf blood examination*, blood count*, rtfftaCexaalnatioas, teat* for ra4rfmfvffl^^ty, Vaasaaann reaction*, animaly4ADC0ftion experi ment*, redMns, aad tba proaanca of tain* ai^tala, urobilinogen and uroblSSr^jgOv of vnejnen worked together end m&ASBrkia in vat place* in* featad3xS^ata^Q$tep* ng taken to rid tb^icVnd* of rata, oa no further cajfi brt occurred ijtminej m' ^ 513 ICHEEAZ. xtxnmzcx 0T A PASAL CASS Df A 71SS M&CEMfT. H. V. IltotL __ 219*29 (March 1939) This la aald to ba tba from Vail*a dlaaaaa (tea Abatraet 433, 1939) la this com daacrlbad along vlth Tar7 careful laboratory testa* Urlaa o tba natlest'g admittance to tba boapltel was injected Into a b dake^pad Jaundice on tba 12th day and died vltbla 24 bra* Oa a >*piraa, er gf^h**a to be avanlng vlth typical I spread uhtforaly ha liver aad vara abundant in tba /fuSSiar opit 'second guinea p^g, ated vltb tba urine of tba flrat, al .croaeopically no^splrocJ .vara vlalbla in tba patiant-'s urlna 'guinea plgaf blood or- ;nwgmc OTBCXETCBnJTT 07 trom and P. V. Tlwraen Contrlb. ^ (Januniy-March 1939). 'From a review of tb* literature and new experimental action of sulpbur dlorf.de on plants ba* been Increased made are a* fallova: (1) plants are aora resistant peraturaa below 407.; (21 resistance generally 4 tha relative tnm&dlty, (3) plants grown with an pl susceptible then those with an Inadequate supply, (4) are more euaoeptihla than plants In good soil, (5) re (a* a heavy abode) below 39)6 decreases tha resistance, more resistant than older ones* A second paper on the a later data* BIQ2XB INXCRT. Carl Institute. 10, 135- knowledge of the of the conclusion* phur dlorfde at tea 's vlth an increase in y of water art more a grown in poor soil in light Intensity yowg plants are la to follow at VP Voi. r. FOUNDATION FACTS . Tfela B.*v>t*ttr U montbir to nimUr eompABi.* *ad end* bmocuuori taii*c4 with *1T Hrtliw raana*tloa_ lu purpo** to roort foodtioS 0w 4hd BBtmUM. Air Hr(t*n FauadAtlah l* . P*rtor,Blp at industry *nd to pntoet th h*lth of tho iilloB workmaa la hoar7 indudUT- i EXHIBIT \ September, lyiiy -- " | PLAINTIFFS i EXHIBIT n I oL lUM-l-ll? )1 Are You Missing Any Bata? no. r A safety engineer In a company iliated with Air Hygiene Foundation was ( recently obliged to design some exhaust ant. He spent much time and effort ^ \ looking up^data, none of which prov pful. After the installation was ` pletod consld ty^>k the engineer chanced upon two of the Foundation "Design of Exhaust Hoods* and "Design Work for aiaed; ' (T^ oil mo about these bulletins?* what I wanted!" *' ^ v Tho b dust on someo know his FoundatfcaJlCtcfBord* > jailable in Me organization al|lrtW>ftme, gathering noer didn't know such buAletvSe existed, didn't *<^1 what services the Costly casee all. n. Dr. H.B. Heller, Managing Director, urges Foundation a. the value of their mmsbersM^e, Inform all interested indlvi _ of your membership in Air Hygiene Foundation and tho services tliey^i through this meaberfMp. A circular describing these services is en onal copies are available for distrf------ bution through your orgoni ' board posting, etc* Incidentally, do . you have a complete flle^ Cjpfaj^<fatip>jh' _v Publication lists are furnished upon request. (See ssue IHtUSwIAt MZDlS pp* 324-25, for a good account of tho Foundation*3<^ascly3 ties during 'th=^st Plans Progressing'"?^ ,^n^^^etlng arc progressing for the 4th nee ^ at Mellon Institute, Pittsburgh, Novscjrtr 1 _ !tion for presentation forces expansion of^thd^p' `conference this year. The program Is being kiydd^o Mako for Healthy Businoas." . Air Hygiene Foundation The wealth of important a one-day to a two"Healthy Workmen Technical data include: Reports on Foundation^^engineering rosearch at Harvard by Philip Drinker, Chairman of the Preventive EngQmering Caamittoe; roports on Foundation's medical research at The Saranac Laborutory&EJniversity of Pennsyl vania by Dr. L.U. Gardner and Dr. E.P. Pendergrass, rospooti^^. Reports on lato^t dovolopments in employeo health protection by Dr* A.J. Lanza, dayman of Uodical Committee. Dr. Lunza will also preside at a symposium on abaehfheiaa which v/ill develop measures for uso of member companies in reducing lost time through illness. ;.i - w On the managements! side, Andrew Flotchor, Vice Proaident of St. Joseph Load Company, will point out specific dullar-and-cants savings resulting from proper health precautions. 7.P. Ahaam. Executive Socrotary. National Industrial Sand Association, is to preside at a forum, designed to show tho Importance of employeo health in all employer-employee relationships, the impact of health on labor and community relations. Theodore C. Waters of the Foundation's Legal Cosmitteo will discuss legal trends end developments of 1939 affecting Industrial hygiene. mi* MvgitNC fQuwmwati