Document GaGJjbmLdZXExGLLwy7aZ4eq

R&S 102901 DEPARTMENT OF HEALTH. EDUCATION. AND WELFARE PUBLIC health service CfcNTKH loll niOTAM- LCVTnC. September 1, 1977 MTu-iM. IKSIlTl.ri' ros OLCUPHIOHL SAFETY AND HEALTH (lOCEKT * TAFT L A DOf( A TOH I E S A C7C COLU A* E< 1 A PAKKWAV CINCINNATI OHIOAS226 T. R. Torkelson, Sc.D. Corporate Medical The Dow Chemical Company Bennett Building 2030 Dow Center Midland, Michigan 48640 , Dear Dr. Torkelson: Thank you for the information concerning angiosarcomas associated with vinyl chloride in your letter of August 22, 1977 to Dr. Spirtas. We would like to obtain more details on the cases new to this office and would, therefore, appreciate any additional information you have on these, or better yet, the name and address of the person we could contact for more information. Also, to your knowledge, have these additional cases been microscopically confirmed? In regard to your question concerning the U.S. cases, you are correct about the name of case 18, and case 23 was employed at the Great American Chemical Company in Fitchburg, Massachusetts. In regard to German case 8, I have enclosed a copy of the documentation we have received concerning the German cases. Several weeks ago you mentioned correspondence among Drs, Philip Landrigan, Hans Popper, Louis Thomas and Marcus Key concerning the validity of U.S. cases 14 and 15. I was unable to find any such correspondence in our files. I telephoned Dr. Thomas and Dr. Falk in regard to this matter and it was agreed that case 14 should be removed from our lists. Dr. Thomas stated that case 15 couldn't be discounted as an angiosarcoma since it was microscopically confirmed but that a determination couldn't be made as to whether or not this angiosarcoma was VC induced. As a result. Table II will not be presented in the Current Intelligence Report we intend to submit to JOM. i t m 4 Page 2 - Dr. T. R, Torkelson Since I spoke with you last, two more U.S- cases have been reported to this office, 1 have enclosed a revised copy of Table I, which includes these cases, plus the additional cases you provided. Again, thank you for the information you have provided. Sincerely yours. Enclosure Rose Kaminski, Statistician Illness Effects Section Surveillance Branch Division of Surveillance, Hazard Evaluations, and Field Studies 1 R&S 102902 I (. i t i AUGUST, 1977 TABLE 1 REPORTED CASES OF ANGIOSARCOMA OF THE I.1VCR AMONG COUNTRY BELGIUM CANADA CANADA CANADA CANADA CANADA CANADA CANADA CANADA CANADA CANADA CZECH. CZECH. FED.REP.GF.R. FED.REF.CER, FED.REP.GER. FED.REP.GER. FED.REP.GER. FED.REP.GER. FED.REP.GER. FED.REP.GER. FRANCE FRANCE FRANCE FRANCE FRANCE FRANCE CASE NO. 01 01* 02* 03* 0/.* 05* 06* 07* 08 09 10 01* 02* 01* 02* 04 05* 07* 08* 09* 10 oi* 02 03* 04*. 05* 06* vinyl chloride polymerization workers 1ST VC DX AGE YEARS TOT. BIRTH OR PVC ANGIO- AT 1ST EXP. YKS. DATE EXP. SARCOMA DX TO nx EXP. 00-00-00 00-00-00 00-00-00 00 00 00 12-15-13 00-00-44 00-00-55 41 10 11 03-06-14 00-00-43 00-00-57 43 14 14 03-26-19 00-00-41 00-00-62 42 21 20 04-05-19 00-00-45 00-00-67 48 22 22 05-07-11 00-00-44 00-00-68 57 24 05 12-15-19 00-00-47 00-00-71 51 24 23 11-09-19 00-00-46 00-00-72 53 26 25 05-13-20 00-00-61 00-00-73 53 12 05 07-19-21 00-00-46 00-00-74 53 28 26 05-16-15 00-00-53 00-00-76 61 23 14 00-00-28 00-00-57 00-00-73 46 16 16 00-00-26 00-00-51 00-00-66 40 15 15 06-04-30 10-01-56 09-19-68 38 11 11 07-26-31 10-14-57 09-25-70 40 13 12 09-04-30 04-16-57 00-00-74 44 17 11 01-01-32 12-16-62 00-00-75 43 13 12 09-29-26 04-15-54 00-00-75 49 17 12 10-19-17 04-19-54 00-00-75 58 22 21 12-13-34 12-02-59 06-16-76 42 17 15 AWAITING DETAILS 04-15-24 01-00-46 02-18-67 43 21 19 06-03-11 07-06-59 01-08-75 63 15 12 00-00-19 00-00-46 01-00-75 55 29 29 01-27-27 10-19-49 01-04-76 49 26 26 01-29-38 00-00-65 04-00-76 38 11 10 04-14-34 00-00-58 09-00-76 42 18 17 DATE OF DEATH 06-29-76 09-02-65 12-21-57 03-22-62 01-21-68 07-05-68 04-10-71 12-24-72 06-12-73 09-04-74 04-00-77 00-00-74 00-00-66 01-25-69 12-1:4-71 11-25-74 01-09-75 11-13-75 12-25-75 ALIVE 02-19-67 01-24-75 06-29-75 01-04-76 05-13-76 09-12-76 FRANCE 07 00-00-27 07-01-50 07-00-76 49 26 FRANCE 08 00-00-00 00-00-00 00-00-00 00 00 GREAT BRIT. 01* 00-00-01 00-00-46 12-00-72 71 26 GREAT BRIT. 03 06-02-37 02-00-66 00-00-74 37 09 ITALY 02* . 11-13-29 00-00-57 . 12-13-72 A3 15 ITALY 03* 03-14-20 00-00-53 07-10-75 55 22 JAPAN 01 08-01-22 04-00-53 08-21-74 52 22 NORWAY 01* 12-23-15 03-00-50 12-20-71 56 22 SWEDEN 01* 06-23-27 08-14-51 02-00-70 43 19 SWEDEN 03 AWAITING DETAILS SWEDEN . 04 AWAITING DETAILS U.S.A. 01* 10-17-23 12-09-48 03-03-73 49 22 U.S.A. 02* 08-19-33 11-15-55 05-00-70 37 14 U.S.A,______ ___ 03* 05-25-15 11-28-45 12-19-73 58 28 U.S.A. 04* 01-15-24 07-06-52 08-19-67 43 15 U.S.A. 05* Oi-25-12 05-19-44 04-09-64 52 20 U.S.A. 06* 00-00-29 01-17-62 02-00-74 45 12 U.S.A. 07* 05-03-22 '08-27-44 00-00-68 45 24 U.S.A. 08* 05-06-20 10-07-46 08-00-61 41 15 U.S.A. 09* 11-08-31 09-09-54 03-01-74 43 17 U.S.A. 10* 08-16-13 06-12-51 05-00-68 55 17 U.S.A. 11* 05-27-09 10-14-46 03-00-70 61 23 U.S.A. 12* 11-17-18 09-13-49 05-02-69 50 20 U.S.A. 13* 12-01-21 08-19-44 05-00-74 52 30 U.S.A. 16* 11-04-27 05-08-50 00-00-69 41 17 U.S.A. 17* 05-06-31 06-23-55 10-11-74 43 19 U.S.A. 18* 04-22-28 09-15-54 00-00-75 46 21 U.S.A. 19* 00-00-15 00-00-43 06-19-75 60 32 U.S.A. 20* 08-31-17 00-00-55 01-30-76 58 21 U.S.A. U.S.A. ^ 21* 00-00-10 12-00-46 OQ-OO-77 67 30 22* 10-02-23 00-00-49 01-00-76 52 27 23 07-02-76 00 01-30-77 20 12-00-72 04 12-24-74 06 12-00-72 21 07-10-75 22 10-24-75 21 01-04-72 18 10-20-70 16 03-03-73 13 09-28-71 28 12-19-73 15 01-07-68 18 04-09-64 12 07-24-75 18 03-23-68 15 08-29-61 17 03-00-75 17 05-10-68 23 03-16-70 15 05-02-69 30 07-04-74 4 03-27-69 19 ALIVE 13 J1-02-75 32 ALIVE 18 01-30-76 22 01-02-77 27 12-04-76 U.S.A. 23* 00-00-23 09-08-58 00-00-00 50 00 14 04-06-73 u.s.a; * U.S.A. YUGOSLAVIA .YUGOSLAVIA 24* 25* 01* . 02* 00-00-17 00-00-39 05-27-77 60 38 08-07-10 09-00-47 03-10-77 67 30 04-05-14 00-00-53 04-08-73 59 20 11-15-31 00-00-50 07-12-73 42 23 26 05-27-77 20 03-10-77 20 04-08-73 18 07-12-73 , , R&S 102903 Total reported cases ** 63 * - Indicates microscopically confirmed angiosarcoma of the liver. "00" - indicates unknown data.