Document GKkXDNXeawzmwxYm1JXVKg5oN
FOR bU FONT USE ONLY
AR226-2885
Copies to'
E. I. du Font de Nemours and Cor'-.my
Haskell Laboratory for Toxicology and Industrial Medicine
Elkton Road, Newark, Delaware 19711
HASKELL LABORATORY REPORT NO. 561-80
Haskell No. .13,674
Study Initiated/Completed 7/15/80 - 7/17/80
CD&P Dept. Jackson Lab
Ltted by
SKIN IRRITATION TEST ON RABBITS
Procedure: Six male albino rabbits were clipped free of hair on the trunk and
lateral area and placed in PDA-type stocks. Doses of 0.5 ml undiluted test material were applied to intact skin under 1 1/2" x 1 1/2" 12-ply gauze squares.
Rubber sheeting was then loosely wrapped around the trunk and secured with adhesive tape. After 24 hours, the rabbits were removed from the stocks, the patches taken off and the reactions observed. Observations were also made at 48 hours.
Results:
24-Hour Observation
48-Hour Observation
Erythema
Mild 3/6 Slight 3/6
Edema
None 1/6 Slight 4/6 Mild 1/6
Erythema
Mild 1/6 Slight 4/6 None 1/6
Edema
None 6/6
.Company Sanitized. Does not contain TSCA CB(
Summary '.^^H^SUiaed mild co slight: skin irricacion In 24 hours and mild Co no irrlcacToffTn 4fhours whan tested on ttu ahaved intact gkin of rabbits <
Thia oafrial i a mild skin irritant. In the evenc of skin contact, good
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industrial hyglaiw practice would ba to waah thoroughly with eoap and water.
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Study Direccon 0. L. DkBhiell
0t lBudt July ^ ia6CL : j
J.B. E-21090, p. 67^
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aeport No. 561-80
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