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CHRYSOTILE ASBESTOS--LANGER ET AL
P. 08/16 353
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Table 2.--Comparison of Particle Counts Obtained by Light and Electron Microscopy
Optical Microscopy
Electron Microscopy
Asbestos Bodies Case 0} Ashing KOH Digestion
Asbestos Bodies
Chrysotile
Fibers
Fibrils
Other Fibers
Thick*
Thin*
Platy Particles (Clays. Talc)
13
0
1 14 40
7l
+
21
0 0 0 9 15 0 0
30 0 0 0 4 4 1 0
4 3 0 0 1 2 31 0 0
5 3 4 0 l 15 1 2 0
60
0 0 9 203 0 4
+
70
0 0 1 132 0 1
+
8 3 2 0 36 308 13 10 +
9 0 0 0 0 37 3 0 0
10 1
32
0 1 24 11 0
0
11 9 3 1 8 99 43 7 4-
12 1
0
0
5 114
14 11
0
13 0 2 O 3 17 O a 4-
14 0
0 0 5 74 4 i
+
15 1 2 0 2 55 9 4 4-
16 0 1 O 6 64 6 2 0
17 0 2 0 2 SS 2 0 4-
18 0 0 0 1 15 4 5 +
19 1
0 0 0 7 22 0
20 1 5 1 5 23 0 3 0
21 0 0 0 9 14 3 1 +
22 2 1 0 3 18 8 2 +
23 O 0 0 6 10 25 3 +
24 0 4 O 5 45 2 0
25 1
4
0 16 254
76
+
26 0 1 0 3 23 9 0 +
27 1
0 0 4 77 1 0 +
28 0 0 0 18 168 13 3 +
* Thick fibers, those with length:diameter ratio < 10:1; thin fibers, length:diameter ratio > 10:1.
ubject to atto amphibole for "survivor :n fibers are ! in all, withne must feel ysotile asbes-
Table 3.--Distribution of Chrysotile in ____ 28 Cases Studied
Group 1 2 3 4 5
"Blank grids"
No. of Chrysotile Fibers and Fibrils
9 10-50 51-99
100-200 201
Cases 4 11 6 4 3
9
Men 3 5 1 4 3
Women 1 6 5 0 0
M|
mately 45% have been found to have what appear to be asbestos bodies in their lungs. A still larger proportion had "uncoated" fibers present (I. J. Sehkoff, MD, unpub lished data). This is in keeping with our observation that asbestos bodies represent a small proportion of fibrous particles present in the lung tissue of asbestos workers.
For the present investigation, 28 consecu tive cases were chosen (Table 1). All had been longtime residents of New York city;
3 based upon | we are to seek chrysotile, it would appear none had been asbestos workers. In each, the tudded with , necessary to include a search at a submicro lungs had been frozen at autopsy. From
scopic level.
each, inorganic materials were extracted for
ios is unlike-
study.
dles in man.
Present Study
This investigation was undertaken to de
it are easily
termine the presence or absence of submi-
ize range, are ated or, if so dirysotile. If
Our laboratory has been concerned with an investigation of 3,000 consecutive deaths in New York city. Of this number, approxi
croscopic uncoated asbestos fibers in the lungs of urban dwellers who died in New York city. Comparison of light microscopic
Arch Environ Health--Vol 22, March 1971
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