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Lp CENTRAL ANALYTICAL LABORATORY . . Repost No... 8230.___________ DaMtay e16;.197. 8 . SSuubbjjeecctt:: F CC--114433 AAnnaallyyssiiss ooff IIRRDCC 113377--009300 SSaammpplleess Re~qeuqeusetstoorr::..._....I~....EE.o..LLo~nzg~g..... DDeepptt.. NNaammee ..RQxicology. Reports ~Reeqquueesstt NNoo.... AG8A6681661.@_.___ l%eport : DDaatteedd....... A_4/JA~29~/.2[8~. Proj. No..2172)J9004 ne, ECTIHZ sor ver iver mCnSSoooeennnrrtkkuueenemnyytaa.&ntn~g,~*ivtar~erfroomn IIRRDCC ssttuuoddyya11i3377v--00e9900d((990f0orddaayaynassluuybbsaaiccsuutteeofrrFhhoeeuss1uu4ss3 ....~ived for analysis of FC-143 content. / Monke~// ~ Rhesss ~~" /~ ~ ~ #.... Cem / ~ Ser~ / ppm pa Liver ppm ttLooittavalebrug 773366224M Ss -- 00..0055 33 773388668~ . 1 1 00..0077 s5 360m Anmly PT 1cal 5 3 250 277333666664MM .(Pro 503 3 - 250- [73e84SF 73052 48 - - 6os5 s0 27 - a3s50o - 7385F 50 - - rasan - ves 773366334M 7458M i100 mmgg//kkgg//ddaayy " yyeess yes 773322887F " 77338833FF " yyeess yyeess n - a4s5 99 71 - 79 - 7711 l100 -660000 - - . 73736677MM 774455554M 73828 . no 7382F 72878 . no 7387F 30 mm~g//~kgg//d~aayy -" " " nen0o yyeess ~O ~O 74564 7456M 1i0000 mmgg//kkgg//ddaayy nnoo 77230811pF ." no no M == mmaallee,, PF == ffeemmaallee -- Sez. 114455 Xs --- NG --- & - ia0w0 - 3a2s5 66000000 2200000000 ib Exhibit 11117733..00000011 Swtozse3s0T 3M MN02343997 | Rhesus | Poticar RPeT n) 1173.0002 3M MN02343998 11117733..00000033 33M_MMN0N203234433999999 age GENTRAL G ENTRAL ANALYTICAL ANALYTICAL LLAABBOORRAATTOORRYY . . RReeppoorrtt NNoo.... 86921190 __________ D Datea .....t Mi.aa.yy. e 161631. .010977.88 . SSuubbjjeecctt:: PFF CC--114433 AAnnaallyyssiiss ooff IIRRDDCC 113377--009900 SSaammpplleess R~eeqquueessttoorr:: _-._._ I.T., .EEo...LLoDznug~.._ DDeepptt.. NNaammee .._.QXiGoIo0Y. RReeqquueesstt NNoo.... AGRAE6L8661.6..__.. DDaatteedd .o.o..A~YL~e A9~.Ze ~ ....e .... ~Rteeppoorrtt:: Proj. No..2372330004 SmSoeenrrkuuemnyaanntddoxillciiivveteryrsswifftrrhoommFCII-RA1DD4CC3)ssttwuueddryye 113r377e--c00e99i00ved((9900foddraayyanassulubyb'saaiccsuutteeofrrFhhCeesnsuu1ss43 mCcooonnntkteeennytt..toxicity with FC-143) were received for analysis of ~C-143 sMoonnkkeey~ DDoossee SSuurrvviivvaall SSeerwunm LLiivveerr LLiivveerr Rpppmm eppmm ttoottaall yg 77336622M8 o0 773388668F 0 yyeess - - 00..0055 3 3 yyeess 1 1 00..0077 s 5 73733666644MMM . 33 mmgg//kkgg//ddaayy ." yyyeeesss 55a33 33 - -225500 7366M yes 48 - - 77330844rF " . 73058 . yyyeeesss os6s05 77 - 335s00- 7385F " yes 50 - - Ta7733s66a33mMM " l100 mmgg//kkgg//ddaayy " yyveeesss 7458M yes 77332288F8 " . yveess - 77338833F8 " . yyeess 44n55 99 - 71 - 7 - 77n91 ow- l0 -660000 - . 750- 750 77336677M 3300 mmgg//kkgg//ddaayy nnoo -- u12s5 88000000 77445555M0 " " yyeess 114455 600 41O00000 77338822F8 " . 73878 . nnoo - 080 77550000 no - us 000 7387F " no 125 9000 77445566MM 110000 mmgg//kkgg//ddaayy nnoo 773308118F " . nnoo o = male, P= female M = male, F = female - 1i0000 - 3a2s5 6600000 2200000000 11117733..00000044 M_MNOZ344000 3M MN02344000 SaA.nR. sens #6919 <a - 2 - v~ayy 1166,, 11997788 AAFS9lI0l0ttuhhidosoaunyugghhrTaotvnneoolsseetffuwfdfayeerccettasstsibR ((0vpperrr-eeellTs1ii.lma0yii0nn0asayrprhyypomcookcFbbeCssdee-;rr1Rvv4aa3Rett,oiipvootennshr))eRs:wwmooeenrrthkeeRee'ysgsspeeeeonnaatddtuutoerrhyeiivnnaghgiisgtthhheeer we dssottsuuaddgiieeedd laeavttelaasppppwrreoorxxeiimmaaattdeevlleyyrse1il0000y affected; however, the monkeys were ttiimmeess greater concentration t~han the . oFhNrs$Siaoa5thtgtEm5eshee2.coSetltSnxehhNsitvaaAeiettRlhniEstabbooioiwttooRhhhhfneIrmosFReeaCfal-alle1seePM4r3saowa.fniin.dtddh,fIfSertnieamnmmtasaislsele,eretiosmmTonnontronleSknkyrceeeeeyhystrrsshtnseeinsamgsccSaeocolmuutmueemommlriuuawllsataaBapestiteceecfhuTfooFlFuo~pCaCtnt--lnede1Ld44nt33rtcnoeSgbctIoaoo~meoroednaaenitbbnInaoodgiuvsaLntenttoShhee aHtCfcahaoiseaide.thcieoene aacHaelllsauossutisee eoessdndttuuaoaldftieefoddSePnrmm3oaaaefllt.memaalUlTrSseaaittngrTneaaoartnnp'ddsttooufrolnvVeuaeenntdrEddeLisEfStryyaoSpsnietSeidiuiadttybhhereeexwrercirriteeRhihiutssii.pobneeFferemofomaflFaluleeo.thrheeossottccuueoddtimsyaapnnooooouirrlncedy. oono aabvinons TquesYtion,Lahaptsis8the aiserence in toxicisy would tile results agree with the IRDC (137-089) study~ One obvious question, what is the difference in toxicity ooff oocsttaannooiicc acid, ammonium salt and FC-1437 /iz Gis. reoier c:H.E. Freier Yh hien J.D. LaZerte B.W. Nippoldt Mba RxA,,Prokop ., F.A. Ubel SE hen D.G. Weiblen 201s 201-IS a 236-1 201-IS Hl 236-3B 220-2E doris 201-IS Quel Lo 11117733..00000055 3M MN02344001