Document GJ48dMXmZpZ3qj8Mpg3v7xY7

. - search , a E n g in e e r in g C e n te r '/ ; -T : August'iX';'-f . i 'y. '1 . .: i- 1 ;a . _ 1 i FDA. MEETINGV-j'ASBESTCi: 17 COSWETIC TATJCS ' .: AUGUST; 1, .VS7i - WASlii NCTCN', .-DvC. , ; *- - X r . W *1 1: \. : v '.t i The. p u r p o se ' a r id ;-li's t;fo f.-p a r tic ip a n ts and .d i s c u s s a n t s are;,-given in th e L$att^ ch ed j,tw p 'ifan d ou ts from th e m ee tin g . . | t- F J* I . | : f Summary./ | ,v .. ; li | ,| ; '| ! ' " jM : ; ' ;' * Dir. Ronver^iKG-.S'e^ar i^ e r it a | a j.r Re s o u r c e d ) . s e t ^ t h e t a c i & f o r / , ; trie m eetin g a^`d /r e d t e r a t t e d /h is /id e m a n d s " /t h s t /f c h e ; FDA: . -Si- - f_ I f -'4p e c i| jy. lijMs!!p r o c e d u r e s . ; f 6 r e v a lu 'a 'tih g ;''ta 3 :d ;-`, : A" ' '{-, .\ 4 $ ,ev al'u ; |fcq | i'-' . g | p | I i / f* y -vi " f %] m f ' i l l CRMC-TALC-000045 j- A ugust. 1X1/ 1 9 7 $ ' \Vf . r : 2; > \ .3 iv h ' i.."....'.................................... I :L ] > % i4 ? ? . $ !* > FDA MEETING,;: ; ' .`..J. ... ASBES'a'O,? IN CO|ME^IC>:TAECS :' j .V . -- - f . n- % ' " ; -M : | Verm ont t a l c s iso d rcia m o lite o r o th e r asb esto s m in era ls. r o e 6C '. t r e - . ' \ ' . . . O il Lewis: J . c fal ey ;|;;- R a tio n a l,. I n s t i t u t e p i1^O ccupat[ion'ai' ; * .| ''S a f e t y a n d H e a l t h ', `C i n c i n n a t i ! , Ohio- ' ~ y .... ......... ......I Review ed ^ d e fin itio n ! o f f f j|ber" 'and r e ia .te d : th e hazad to ii, f c i l i t y -an<i. timej;'b.ftbfcL-..'e^tjiO.sUA-eV^.. In tr o d u c e d , agaiii::th e-.con cep t: of' heavy .h e ta l'.c a r O in o g e h Q s is . ./Revi'ej^e.dS' H is.^ p u b lish ed sfcudy' o f o"; ta lc .- d e p o s i t s .. .-^V' v 'y. { J. .;'!.v ' v''dr-. :I p p : -: .'. fi>fr` I Dr . Ir v in g J~|. S iflik o f f 'Siria.l'IiS'cHoo^r'bf :fMecllcirie .{ v e : h i s 1u s u a l : ;a s b e s t o s p o r k e r s - s t o r y . f o i l o w i n g .th ro u g h - .to.- h r s CRMOTALC-000046 => ?'_*vyjf;.j A ugust 1;1 , 1 9 7 1 * _ P'.-.Kit v 3 . FDA. MEETING A SB E ST O S t 'I N .C O S M E T IC , TALCS j e c t 'i b n s | o f? h ^ s t ; e r - s ' > i i h ' ; `t i i r e t y p s o ^ 'tS lc '-V {hgl! n i c k e l ; low n i c k e l / `-a n d '' i.-. )i |rE ^ fe ^ ffc ^ 8 m tiic \ . t 9 c ) ^ ' ,'fW o ^f fii birridts i s a f t e r ttwwoo. -yyeeaarrs >.::dd'd'dflaFpii^^eb:i ^ x^ c s as 'lit^yV`-^`ii9^0oUv7m Etfpc:.-^u's^,edd^\,;vf'-'t`'!Ei.. n ottee'cd ?Xan W e b s t e r ' s c o n c!lssiw1,s.v;.;th't.'-< f b'rs`m u.9C b' . a t 1ie a s t- ;.5 .',;n jic r o n s .ilo n g ..to . b e 1 * ihiaaJirWmi,Uf uJLl 'V. *, ' *1 .t. i '.;s v.' . ^ i* *' ' * .;y:i'y'.'.v ; ' ; '. , /, . ; wi. - D r . MorJ l s -'K a p la n .:j. C o n su m e rs. U n io n ' , R f ty |c?t .condiim ei: a n d .^ t h a t ' ;; anu>Kf,ii'&'i riVrifirtvihdffl ithii.'piihilfirihi on 'and'" "hanniria11 f t a l c ' CRMC-TALC-000047 ^ 3f? ? v - - **./ V` _ - '' . t. **..' >T.', ' ' ' . A u gust 1,1 ,f.'1971j,V- r P.aqe}\ 4;. J t.'; > ' |. i. ' ' r .j- ] | ' FDA M' EE*T'ING ' - , ' ft ASBESTOS ik COSMETIC TALCS 5 y fl !. f .c,` i'if.*. ". x I iV * i. f. vVV ,,v-^.v1-' subject', off1 i'fe o sjin 'sin jfe e ta b iG d r u g s aid s ta te d '- th if it m ore t h a n :o n e - h a I ; f i ;o f | i . n 3 e c i a b l e , d ru g s , i n . a'< s u r v e y a t - t h e w t . S i n a i H o sp ita l Pharm acy c i n t i ih gram in a . ' v i a l . '? >' a s b e 'fe to s 1 'h ' 'A m o u n ts uup .r*toff1-.t"1 m i c r o - : -t.., - - I V . f - :`Sv j;-<. S .' Spell.- -j-Jo n n s -M a n v ill e > I ' a if: * ia itb o rrie -' and c o u n t i n g by A C G IH m e th o d s ':u 's in g i r^condze'<3- TLv'f'iw ith an ."expor-v - su re ' tim e"| fa c to r . j ;- i CRMC-TALC-000048 'tyr ' *h*-: v ' *t-y\ J .* *. August; 1 1 , 1*971 '|;i- *. Page"-. '5 , '. | :j. *' r\ .\% ' {;*>> V I^>'' - 1 ` "A**.*. i .. V .'T7. > ' j' -i ; f f rDA MEETING I I f* ;: "i" I F . tv , r : vi ASBESTOS I& COSMETIC* TALCS . . . L ; ; | v \ v jt V - K . i " I.- T . . , I ' mJcrolscopyl'. ; Irt'di'^ated i.a p p r o x im a tely oiie vbbk;. f or^ com-: *. c a 't i n g . p re se n c e ^ - o|;* f l b e r s f b y EM a n d " c b ry io fc jL le '' n o t v v e r i f ied:,; by e le c tr o n ififra e .t'io n v V s t i l ' f e e ls i d e n t i f i c a t i o n o f c h ry - s o . t i l e b y 'slrapev 90.' t o 95 p e r! c e n t c e r t a i n .* . ! ' i - r v - ' p i - I : I :? : ' J' r . . - 'j {.. ' * ' . . ' Dr,. Norwood - ChaS;. P f i z e r 's. Company' j". CRMC-TALC-000049 m -: w * *r^^ ' -# |: t , ; I r ;': ; : , - i ", AU i i , - j j L 9 7 1 > y ' r ; v v; , v - , PPaa<'cjrro 0 * ' ." i i '"; - ;t . I FDA MEETING \AslESTGSylti^ COSSETi`c . TALCS. ; i '* T;-" ' . V ' * ! , > / v-\/ * -a " y . ~J 2. 1 I;|drma|priesi|te i s . fib r o u s orm'/:.. D i^ e t e r ? o f 200 Angstroms V w ith a f-h o ia '^ dow n; t h : c e h t e if . /Hydrdmagne'si'te i s Known t o - ; ''I' |n d h g|^ ch r^ b ^ i!le:: vVj^heir'.. Dr . F J p , P o o le y f - U n i v e r s i t y o f S o u th W ale's v i - - | v l . ' - . % 'I : h . ' * % r . R.-. F .. R ^ l l e t Johnson-1& J o h n s o n 4 Showed] beau- t a l c . f S am pi' N :-|p l a t i n i ,' 'r-- f 1. 1 Led, upi: p l a t e l e t s o f ; g o ld ';.p a lla d iu m ..;. Diri ' W.'VF .7 Ni'i 1 . a i r 3 am ^lingi- t e t s ^ h d ip o m p lp te v a n a iy s i a gironi ,-a f s ejected'sv---'^amut o f 's a m p le s a^ tef,i-'p rii^ iria ry :s^r,eenihg/>'. a s' ab o v e;-., * 2 . sta tistica l Wi n HV^1^ 'Y .S i f l C ^ q d i j,4 1 i>-i i.ungs.-Jwi fch; dj g - . s |r v l y sampl e ^ , fi;- sh i' Kn`r s i * i i i ^.T'/nl. f*'ish t 11r \ . f*Ko - i^ &'iti , 7Iti;-.. v*' .-' :' v ; A ;5 'aNwSilSwaRfci** y;~ & i .( 2. CRMC-TALC-000050 *1 *' . .' . .i -'. -`.'' ',:' '': '''p.---- ,. V- .--' vi ::-v j ->- '.- {. %. rTMf *'"*-- '?' >y ' .'.'.. ' **'".. ' -y '.rj> ;;:. - rij>-- -y%H- rr.-- v; ' . :'- . ''{i;:.- 9 t'" '._";\ -'" V*'^.>/-/!--}.' ' ;A ugust 1, > 1 jf - r:^; . y*' ;;y J>.. .^':?r r:"7 .7 ;J;. S;./ V <: Rage" 7 ?. . .&.&:'?%', vf"-^ ..' :.: ' A- ': .'7 : .' ;-y v.- * ' ' ' ' - H i- -,y.- ~ 'r & . ;. ; ' - .% .y '"2 -*'ts '4 S d y r?'` ''Y ' l i 1 i h ' M k i i ' * ` T V . .. / .(>, L i'V T " ' ASBESTOS^ IN :cdSHTIG ifr m s y , . - ' S i '4. -V. '3 .. ' : ' i a ; : c o r p ^ t ^ ^ ^ ^ l a :.^ u < y o f ^W e. w p r k e r s f i n i n g and T .. ., ii'IJ :: . " ! '.. ' ; ; . J ': 1 '. / - ' C. M aggiore vSina'1 Schtoor Of ^ ed felvi $ sirm n^atior yfoE;comp'Iy hafc'tgr/izUngfcmany^ari'ial 1 H ;''andparticresriiv:aT tS^slfajde;,:^ jt* , . s i s ' ; . . ^ ^ tHQ:inai:d^th)^xi^& 3^ % 3 ^ ^ ^ m a ^ ^ ^ 3 p 0 ^ p p 0 $ mSs fa I# m m '; " ...................................................................................... ` ....................... `S^;<.'SPIB SS/.f ;.?;; , | : At tcHrriri fcs1 {2 )'.:{,|: * ' H .7 fv WjiV-P'. Ra in fe stf^ p tfo # ; . H; 'SWtoni'c.^'''DHt^y;, C. B-. Shk.tfDH, f '..,.v>-A.'ji;;vJf*.A-i22S*W3ffiffe;;*v 'i.. mss53j * 'B V y 'H u tt ' ^pfsS{ bIwi VASv'-:*- *> CRMC-TALC-000051