Document GEJJJaZDJJ3mpZrmdR0RmrZq

O- ( ^ f *- ^, Gloyno^ ` ^ reproduced bodloa 9 months aftor suhcutanoouo injection in gulnon plgo >f fibers rondored froo of iron. Tho bodies aro abundant; in iaan and in the guinea pig (table l) but ero much largor in tho former, probably becauao tho largar-slrod air passages ad.ait flbore of greater dinenaLor.. Tn guinea pigo they form, after about 70 dnyo of contact with. tho tissue. In oats, rabbits and mica there la an atyp ical coating -of a fou- of tho fibers after much lor.gar rcsidanco ir. tho lungs. In ratriybodioc are rarely coca and in dog3 none could bo found. Although the evidence i3 incomplete, it appears that tho formation of tho aabostosin body provonts druuago to tho tissue by tho fiber. Many of the points mentioned above wl.ll ba elaborated upon in aubsequont para graphs dealing with tho aotur.l experirnant6. ..For prosontation our investi gation is divided into two soctionn, orio doaling with Inhalation experi ments end tho other with injection experimenta. III1IALATIOH E I P E R Ii E H t 6 Four largc-ccale inhalation oxperimontn have been conducted in this laboratory with various forma of aabcctoa dust. In each of those investi gations more then ICO cninalo wore uacd and the experiments wore carried on for periods ranging from 2 to more than 5 years. Tho four kinds of as bestos dust employed aro designated no King's floats, short-fibor, 100 per cent ball-milled, and long-flbor asbestos duat. / 8. Lynch, K.W. and Smith, H.A.j Asbostools bodies ia Sputum and Lung. J.A.M.A. 650, 19JO. 9. Simnor., F.7-. and Strachan, A.S.j Asbcctouln bodies in tin Sputum; A Study of rpoolraona from Fifty V.Vrkors in an Asbestos Will. J. Path, and bot. M: 1, 1931. ^