Document G6NkLM7y2nROZVwB5RpOOVmz4

0 Liver Angiosarcoma Caoea Clrculatlon Or A Hoes Adorns, Air Products Hr P K Anderson, Wilton Dr V C Surnes Jr, Honsento USA Dr John Dorr, Air Products Dr Peter Dexter, DIAS Dr Brian Bennett, Hlllhouse (20 copies - 1C1A, ALCI, Duperial) Dr Piethe Bertaxxi, Milan University Dr Beache, Dynoait Kobel, Troiadorf Dr F W Best, Everberg Dr C Bishop, EKAS Dr E Bougas, AEC1 Lid, Plsatico Div'n, PO Box 1122, Johannesburg 2000, South Africa Dr David Bryson, AQ Division Hr David Burgess, 1C1 Americas Dr David Uyren, Xeaanord Dr J T Carter, BP Hr C Celle, Hontepoliaeri Hr M Chance, VCH Technical Manager, Hond Hr P C Claus, APKE Hr Harold Cloyton, Morale Hydro Dr Conlasaot, Chloe Chiaie, St Tone Dr E W Decay - NIG3II, Cinclnattl Hr J 0 Doviee, Everberg Sir Diehard Doll, Vnrden, Green College, Oxford Hr Q Dupont, APHE Hr H Emnlnger, VKE Dr V Ernst, Berufegenoeaenscheft der chealachen Industrie, Murnberg i Dr Henry Falk, CDC Atlanta Dr D M Ferguson, 1C1 Americas Dr H P Friedel, Benifsgenossenscbaft der chesischen Industrie, Koldelberg Prof L Oolberg, Duke University Medical Center, Box 291*1 Durham, North Caroline 27710, USA Dr I fi Goextonyi Jr, Tenneco Cheeficala, Saddle Brook (KJ) Dr Valter D Kerris, Uniroyal Inc Dr Donald V Ilillaon, Diaaond Shaarock Dr Hobart X Hioderer, BF Goodrich (Cleveland) Hr J Hodgson, EHAS Dr V A Hogg - lap*rial Oil Ltd, Canada Dr J K Howard, Wellington Clinical School of Medicine, University of Otago, Wellington Hospital, Wellington, Mew Zealand Dr K F Huaphry, 1C1 Australia Operations Pty Ltd, PO Box **Jill Helbourne, Victoria >301, Australia Hr J Jauvert, Chloe Chiaie, Paris Hr H H Jervis, Hillbank Dr H M Johnson, BF Gooilrich Dr Druce Karrh - Dupont Dr R A Xrueger, BF Goodrich Dr J P Lalolne, Solvay Hr J Uivrcnce, SP1 Dr F I Lee, Victoria Hospital, Blackpool Prof W K Laibach - University of Bonn Dr D A Lev icon - St Bnrlholoiaev'u Hospital, London Dr P Lewis, CJA Hr Lolivicr, Solvay Prof K N K MocSvecn - Western Infiremry, Glasgow Dr J H Huillard, Hediziitiache Abteilung, Suva, Postfach 6002," Luzern, Switzerland Prof C Maitonl, Bologna Dr Kcnxo Kottiussi, Kontedlaon Hr Kokka, Neste Oy Dr K Honteaano, larc, Lyons Dr A A Motti, Duperial SA1C, [hienos Alrea Dr A Hunn, Monsanto, Brussels Hr M Kunox Houton - Rio Rodano Hr 5 Nokaaura, Japanese PYC Association Dr John J O'Sullivan Mond Or H Owen - TUC Dr G H Paddle Dr S Pagliatunga - Montedison Dr Mans Popper, Mount Sinai Medical Centre Dr J Poseberg, Wacker Dr Juaea Purdhaa - Canadian Centra for OIIS Hr P Rangnea, Norsk Hydro Dr R Saracci, larc, Lyons Dr David Seronne, Diamond Shaarock Dr Paul H Salth, Llandough Hospital Dr R Spirtas - NCI/NIH Betheada Dr Carol Stack, CKA Washington Dr J Stafford Mr Stahnecker, BASF Prof C H Taaburro - University of Louisville Dr Gary Ter Hear, Ethyl Corporation Dr B Terwiesch, CWK Dr Cillea Theriault - McGill University Prof Dr Thless, BASF Dr E Thlla - Eveneen, Norsk Hydro Dr W Tordoir, Shell Dr T R Torkelson, Dow Hr J R Wallace, Esso Chealcal, Sarnia, Canada Hr S O Wejdling, Xeaanord Mr H H Wheeler, UCC Dr J Whiston, Hlllhouse Hr X K White, Duperial SAIC, Buenos Alrea Dr 1 W Wlllisas, Norsk Hydro Dr D H J Williams, DP Berry Dr X S Willisaeon Dr Peter Wright, PAP Willnn Kr John Tork, Everberg <A 5 JH * ni in *Tl P - _ :i 'i Lj > /. 17 -Ini. Wi GENC GO8583 I PREFACE ACKNOWLEDGEMENTS, SIGNIFICANT CHANGES AND COMMENTS 1) Since John Stafford's retirement from ICI, I am pleased to say that he has been elected an Honorary Fellow of the Faculty of Occupational Medicine at the Royal College of Physicians, London. 2) I would like to thank Dr Paglialunga for all his patience and hard work in helping me to acquire the necessary facts which enabled me to place the recent Pansac ASL in the Register. 3) I would like to thank Dr Lnundrie, General Tire and Rubber Company, Akron, Ohio, and Dr Dacey, Robert A Taft Laboratories, Cincinnati, for informing me of recent ASL cases. 4) I am grateful to Dr Contassot for sending me information about three new ASL cases which have occurred at the St Fons' Factory in Lyons, and also for the full account which he gave. 5) I should be very grateful if I could be kept up to date with the five ASL cases which I have placed in the Register, who are all still alive at this present time. 6) I would like to express my appreciation for all the help I have been given in carrying on the work of John Stafford by everybody who has sent me their helpful comments and communications. 7) On taking over the Register, I discussed with Dr John Stafford his present format. We both felt this would be the appropriate time to consider any worthwhile comments about its presentation, and also suggestions for any way it could be improved, in order to benefit future analysis. i B BENNETT 17 Jan 84 GENC 00858A IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION LIVER ANGIOSARCOMA CASES (REVIEW DATE - 1 JANUARY 1984) ble Sequence Igium lada jchoslovakla 1 ASL Case Numbers by year of Death (Table 6) 2-3 ASL Case Numbers by year of first exposure 4 (Table 7) 40 41 ince `many >iy >an ~vay ;den 5-8 9-13 14 15 16 17 Western Europe PVC Producers - Start-up Dates vs ASL Cases (Table 8) USA PVC Producers - Start-up Dates vs ASL Cases (Table 9) Canadian PVC Producers - Start-up Dates vs ASL Cases (Table 10) East European PVC Producers - Start-up Dates vs ASL Cases (Table 11) 42 43-44 45 46 l ;oslavia 18-20 21-26 27 Japanese PVC Producers - Start-up Dates vs ASL Cases (Table 12) South & Central American PVC Producers - Start-Up Dates (Table 13) 47 48 :idence of Cases pa (Table 1) 28 trlbution of Cases Country (Table 2) 29 tern of Cases by tory (Table 3) 30 .ency Periods (Table 4A) 31 trlbution of Latency Periods (Table 4B-4I1) -ual Geographical Incidence (Table 5) 32-8 39 GENC 003535 iHmui, chemicaI. indostkiks vlc PKTKOGIEHICAI.S AND PLASTICS DIVISION LIVER Anglos a recnia Osea - (Review Date: L January 19(44) Pig* 1 i i I i AMD t NCE i i I i 2i I i NAME OR i INITIALS i i i t 3t l i DATE OF i MRTH i i l 4 COMPANY it i i i i ii i si6 i j ia i 9 i 10 t 11 i 12 tI t i i i it ii i i i i ii i i FIRST VC i DATE OF i ACE AT t YEARS OF t YEARS OF i DATE OF i HISTOLOGICAL i FACTORY i EXPOSURE i DIAGNOSIS i D1 ACNOStS i EXPOSURE TO i EXPOSURE i DEATH i CONFIRMATION ii i i i 01ACNOSIS i ii II i i i i i J_ ii ni M i I i ESTIMATED i l i i EXPOSURE i OCCUPATION i LEVEL i i ii 15 OTHER CAREER HICIM.TCIITS i i i i i 1 1 1 16 OTHER COMMENTS m.oi.n 1 Solvay 1 Jemeppe 1 00.07 SB | 00.OS.76 1 63 1 IB ii t1 1 1 t ii i1 1 1 1 ii i1 1 11 ti t1 1 1 1 l i1 1 1 1 1t i1 1 1 t ii i1 1 t 1 it i1 1 t 1 |I i1 1 1 1 ii i1 1 1 1 ii t1 1 t 1 ti i1 1 1 Ii i1 t I l i i1 1 1 1 it t1 11 li it 1 1 1 1i i1 l 1 1 ii i1 1 1 1 1} i1 1 t t |l \J | | ti i1 ! 11 ii i1 1 11 ii i1 1 1 1 it i1 t 1 l 1| i1 1 1 1 ii it t 1 1 ii i1 1 1 1 ii il 1 1 1 it i1 1 1 1 |1 i1 1 1 1 ii i1 1 1 1 ii i1 1 1 1 ii i1 1 1 1 li it 1 ( 1 ii t1 1 1 l ii i1 1 1 1 ii i1 1 1 t ii il 1 I 1 ii i1 1 1 1 ii i1 11 ii i1 t t 1 l 17 129.06 76 | 1 11 1 11 1 11 1 11 1 11 1 11 1 11 1 It 1 t1 1 11 ! 1t 1 l1 1 11 1 11 1 1t 1 11 1 (1 t 11 1 11 | |1 t t1 1 11 1 1t 1 1l 1 l1 l 11 1 1t t t1 l 11 1 1l I t1 1 11 1 l1 1 11 1 1l 1 11 1 t1 1 1i 1 11 1 t1 1 1l Yea \ High 1 Autocleaner 1 Driller In a tlLspatlc teats 1 11A yra 1ioundry 1ln Oct 1976 1 I958-I96B | 1(2 yra) (were norma L, f^.expoaed tolPolyworker 1 Farmer 1 Ret 1 red | 200 ppm |3 yra 105 yra) |F*b 1975 1 Eor S hr* l [Work In glaa* | Uoejil t al laed l per dap 1 |lild. 6 cfieml- I Hay 1976 1 and 1 k certainly | } under | 500 ppa | | | in 6 to 1 1 9m3 | | autoclaveal )cal i i i i i i ImJuutry l \Complete |Cl Ini cal and (career detail |are given In . 1 Paper by (llubtet el al | I96S-I972 l | expoaed to| | 50-200 ppm| | 0 bra per | | day In t 1 25m3 | | autodiml t 19*2-19*6 | J expoaed tol i i t i i i t t i kIn Arch, feelg IMcd. Soc., Illy A. Med. (Trav, Med. IU*. 11971 pagoa 1601-622 i i | 50-200 ppnl | in auto* | | clave rooa| i i i i i i 1 1976-100 | 1 PP \ | 1975- 50 1 i i i i i i 1 PP* 1 k RETIRED | i i i i | 1 Feb 1975) i i 11 11 11 11 11 i i i i i i t i i i 11 11 i i i t 11 i i 11 i 11 i i 6ENC 008586 IMPERIAL ClItH CAU INDUSTRIES H.C PETROCHEMICALS HO PLASTICS DIVISION LIVER Angiosarcoma Canes - Review Date: 1 Jan 1964) * All dates use UK system Canada PAT - MONTH - TEAR Sheet 1 ** Data published In Journal of flee Hed 1978 pages 338-340 *" Many of dates altered to fit N10SI1 31/3/77 llat Page 2 1 10 II 12 13 14 15 16 i AND i ICE i t NAME OR INITIALS i DATE OP i BIRTH | i t COMPANY i i | FACTORY t i ii FIRST VC i DATE OF i ACE AT EXPOSURE i DIAGNOSIS i DIACNOStS ii lt YEARS AF EXPOSURE TO DIAGNOSIS TEAKS OP EXPOSURE 1 DATE OP | IHSTOIOGICAL DEATH ] CONFIRMATION i J ESTIKATEO EXPOSURE LEVEL i t OCCUPATION | t 1 OTHER CAREER HIGHLIGHTS i i i i i OTHER coin ENTS SHAW1NICAN 1 111.11.11 1 1 t1 1 11 1 11 t 106.01.1* | 1 11 1 11 1 11 1 11 l 116.OS.19 1 1 11 l 11 1 11 1 11 1 101.0*.19 ) 1 11 l 11 1 11 1 11 1 11 1 107.01.11 | 1 11 1 11 1 t1 1 11 l 111.11.19 1 1 11 1 11 1 11 t 11 1 109.11.19 | l 11 1 11 t 11 1 11 1 111.01.10 | 1 11 1 I1 l 11 119.07.11 1 1 11 1 11 t 11 1 t 19** i 1955 1 *1 1 1 I II 101.09.11 | Tea 1 1 Reactor |0|nerator (Smoker 11 i 1 I 1 11 l leleaner |pp)ymerlmatlonl 11 i 1 1 l 1t 11 1 1 1t i 1 1 1 iI 11 i 1 t 19*3 i 1917 1 (] 1 i* 1 14 111.11.17 | Yea 1 - (Maintenance | Operator (Worked 11 i 1 1 1 11 1 lullLwrtghtt 1 (ovettlme 1t i 1 1 1 11 1 (pipefitter (Smoker (l i 1 1 1 1t 1 11 t 1 1 t 11 l 1 1 1941 i 1962 l 42 1 21 1 20 in.01.62 | To 1 1 lOperator, ! (Worked t1 i 1 1 11 i 1 1 1 11 1 11 |foreman i 11 i (overtlme (Non-smoker 11 ! ! 1 1t 1 ___________ !_______________ I1 1 I 1 1 11 1 1 1 19*1 i 1967 i 48 1 22 1 22 111.01.6# I Ye. | t1 i i 1 1 t1 1 l |Reactor leleaner 1 10perator, |foreman, (Vurktd (overtime 11 l i I t t1 1 |water coolIng |Smoker 1t l l 1 t1 1I lunlt 11 l t t 1 11 11 1 11 l1 1 11 11 i 1 ( 1944 I960 l 17 1 i* 1 01 101.07.68 | Ye. 1 11 1 l 1 1 11 t (Reactor leleaner |Water cooling |Worked tunl t lovert Lmc 1l i l 1 1 11 11 1 \Smoker t1 1 | | 1 11 11 l 11 1 i 1 1 11 1l 1 1 1 19*7 1 1971 l 11 1 2* 1 13 110.0*.71 | Ye. | (Reactor IHalntenance. |Workvd * 11 1 l 1 1 11 1 leleaner |nlllvrlghl lovertlme 11 i i 1 l 11 1t 1 I Smoker t1 1 i | 1 11 1 ___________ !______________ 1 11 l l 1 1 11 1 1 l 19*6 l 1971 1 1] 1 26 1 11 12*.12.72 | Ye. | 1l 1 l 1 1 11 1 i |geactor leleaner t IMachtne shop |operator and 1 Worked (overtime 11 l L1 1 11 l1 Ipoly unit |Smoker 11 t 1 1 1 t1 11 1 11 1 1 1 1 l1 1 t 1 1961 l 197] 1 1] 1 12 1 05 112.06.7] | Yet 1 1t l t 1 t 11 l (Reactor leleaner (Maintenance |In pi ant fmncMne shop |25 yrvl Smoke 11 i | t 1 11 1 ____________!______________ 1 11 l 1 1 1 1 1 1946 1 197* 1 1] i 2B l 16 104.09.7* | Ye. 1 11 l 1 i 1 11 1 1l i 1 i 1 !1 1 (i |Furnace op. i |j>i|ef liter i |ma!ntenunre i (Worked lovertIme |Swokei 11 l 1 i 1 11 11 jf Dr F DELORME In Atmalce d'Anetomle paLholog l*(ue Paris, 1978 Vo* 23 No 2 j>p|()5-fE4 claims this ctue had both a hepatoma and ASL slmul tmurcmsl y . GENC 008587 IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION LIVER Angluaarcuaia Case* - (Review Date; l Jan 1984) DAY - MONTH -YEAR Sheet 2 * Aii datoi (lae UK ayate* Canada' ** Data puhtlahvd In Journal of Occ Hed 1978 page. 338-340 *** Many of datea altered to fit N10SK 31/3/77 Hat 10 14 13 \MD NAME OR DATE OF :e INITIALS BIRTH COMPANY FACTORY FIRST VC EXPOSURE DATE OF DIAGNOSIS ACE AT DIAGNOSIS YEARS OP EXPOSURE TO DIAGNOSIS YEARS OF EXPOSURE DATE OP DEATH HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS Page 3 OTHER COMMENTS 16.03*15 1953 1976 61 23 U 00.04.77 Reactor cleaner Furnace op. Maintenancet packaging GENC 003588 1 IMPERIAL CHEMICAL IMWSTKieS PLC PETROCHEMICALS AHO PLASTICS 01 VISION LIVER Anginearcoaa Csaea - (Review Date*. l Jan 1984) Page 4 10 12 11 14 15 NO HAKE OR DATE OP E INITIALS BIRTH COMPANY --1 t 1 1 1 \ t t 1 1 11 l| i1 1| 128 06.28 | State Co ]| ii ii ii ii 06*07.17 State Co I factory FIRST VC EXPOSURE DATE OF DIACN0S1S ACE AT DIACNOSIS YEARS OF EXPOSURE TO DIACNOSIS TEAKS OF EXPOSURE DATE OP DEATH U1STOLOCICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL | OCCUPATION | l l OTHER CAREER KICm.lGUTS t | 1 1 1 ttovaky 1 i i t i 11 l| ii ii 1 01.07 57 | 24.12.73 1I ii ii ii ii 1 | i i 1 1 i i i i 45 1 1 1 1 1 1 1 1 ( 1 16 1 i1 1 i1 l i1 1 i1 | (6 (14 12.73 | 1 11 t 1i i li i )i t 1! Yea i l t i 1 1 i i ! 1 i 1 1 Autoclave |CleAner 1 t i i i ii 1 IARC letter i [of 1-4-62 1 (giving detail el Ifrns Prof i |A David of t lCent re Ind i |Hygiene and i lOcc disease*. i 1i Hovaky 01*11.50 27.11.64 57 14 L 5 26.11*64 Autoclave Cleaner |tARC letter of 11-4-B2 Rave Jaoaewhat laltereU dates I fur (lit a cue. II have 1 accepted tlie tchmiRua since | the date* cone |fron Prof |A David of the 1Centre of \Industrial |Hygiene and |Occupational IDlaoaaca. My |datee cone (ovlglnally | fro* NIOSIl. J______________ 1 1 1 I l 1 OTHER COMMENTS 1 I 1 I I I I I I I I I I I I I I 6ENC 00858? IMPERIAL CHEMICAIf INDUSTRIES PLC P KT RCI CH EH 10A l. S AND PLASTICS OIVISION LIVER Angloearcotia Case* - (Review Date: 1 Jen 198-4) France Stiect I Page 5 10 12 n u 16 AHO NCE KAHR OR INITIALS DATE OP BIRTH 15 .04.24 COMPANY FACTORY Rouee11 Ion FIRST VC EXPOSURE 00.01*46 DATE OF DIAGNOSIS 15.02.67 ACS AT DIAGNOSIS 43 YEARS OK EXPOSURE TO DIAGNOSIS 21 YEARS OF EXPOSURE DATE OF DEATH 19 19,02.67 HISTOLOGICAL Confirmation l ESTIMATED | EXPOSURE | OCCUPATION LEVEL I _____________ |_______________ I I \ High |Autoclave Iworkcr and (cleaner 119 yra ! OTHER CAKEE R HIGHLIGHTS OTHER COMMENTS Kef. Ravier e i a 1 Arch. H.i I, Prof. I 30 n* 3 Nov 7) p 171-177 1 1 SIM i i i 1 i i i HOR i1 103.06.n 1 PCUK 11 1l 11 J1 1t 11 11 06.01.20 IP 27.01.27 PCUK 29.01.3B PCUK 1i 1 1Brignoud 1 06 07.59 | 15.01.75 i1 i i1 i i1 i il i i1 i i1 i it i i i i i i i i i i St Font 00.00.46 15.01,75 63 55 1 | i i i i i i 16 29 Brignoud 19.10.49 16.01.76 49 26 Brignoud 15.01.65 13.05.76 38 II 1 11 i1 1 1 11 126.01.73 1 Yea i High |2 yre on |Italian 1 1 1 (KIOSII no i 1 1 1 connent) i Inononer 110 yr on Inrlgl n | 1 11 1 11 i lpolyr- 1 t (leatlon 1 t 11 ti i 1 |Ref. 1C Ronneton et Lil "Non*cl 1 e 1 pretf ue |iaedicule" 15 Nov 1977 1 11 ii i Ip 713 1 1| ii I i 1 29 29.06.75 High |Polyworker lI0 yra ae VCX production Ref. Rely et 16 yre a I Arch* Hal. (autoclave Italian POW Prof. I 37 n* Icleaner Shepherd t 6 June 77 I Cowpounding Sawyer, Nation p 551-555 13 yr* _L I 26 04.01.76 High } Ho nonet |production |worker (8 yre_______ |PVC |f 11 tret Ion 118 yra 13.05.76 Yea High J_________ I 1 Polyworker 111 yre 1 I I 1 )Thoracotomy Ref P Courier- 9th Fob 1976 et at "SenaJn- coetut dee hoapttaux eng Loearcona 10 Septenbre 2)ScIntJ graphy 197h found ASL Previously lid 3) Hat-mu iluigu Dune frun ASL uug I ua.iri um.i" 4)K1*M 3I.-i.jit cc t tiny Al Hn t'H tuhou.sk J i- .*1 "l.n Nutm-I Pl'eune Hfd I i`.l QENC 008590 7l li July Vtn 1MIt ?4H5 HD NAME OR DATE OP E INITIALS SIXTH IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION LIVER Anglonarcona Canes - (Review Date: Jan 1984) Prime* Sheet 2 10 1] IS FIRST VC EXPOSURE DATE OP 0IACN0SIS ACE AT DIAGNOSIS YEARS OP EXPOSURE TO DIAGNOSIS YEARS OP EXPOSURE DATE OP DEATH HISTOLOGICAL CONKIRHATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS 16 OTHER COMHKNTS 14.04.34 PCUR Brlgnoud 01.03.58 12.08.76 42 13 11.09.76 (N10SH aaya 12.09.76) (1958-1960) 2 yra filtration 10-11 yra poljrworker and work* Ubt Hi In wan bud AOL prior to AS. Ann. de Hal. Prof. July *77 p 645 4 6, AOL vaa found In 1971 five yra before ASI. 26.04.27 St Auban 01.07.50 After death HIOSH aaya 00.07.76 49 22 02.07.76 Yea (HIOSH no ent) High Plant fore man tn polynerination 1972-6 admin fteCtIon In St Auhau Died of neptlcaemla Snal1 liver lea Ion found after autopay 01.04.34 Solvay 23.05.57 03.12.75 42 19 30.01.77 Hodarate 6 yra packer 6 autoclave clnr 14 yra autoclave worker Had been tunnel worVc prevloualy 08.10.14 10.01.48 26.04.76 63 28 28 25.12.77 Yea Very High Polymer- 10 yra In Operated 4.76 1948-1966 leation aulphurlc for removal of Leaner operator, acid factory, tumour f rom Exposure autoclcaner atorukeeper 6 liver and 1966-1976 autoclave general died after Maintenance nervl i:us eecoitJ nurgteal operat Ion for b (11 o bionchj al f I al til a Pn|>or by Hi Re l jr et al In Archlveu de GENC 008591 Mn I a do a 1'iuleuKl nftn I a Vol 40 No ti 1979 p.itfea 741-1. IMPERIAL CIIKHICAl! INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION LIVER Angiosarcoma Cine* - (Review Date: [ Jan 1984) France SI.cel 3 Page 7 10 12 n 15 AND ICE NAME OR DATE OP INITIALS MATH COMPANY FACTORY FIRST VC EXPOSURE DATE OF DIAGNOSIS ACE AT DIAGNOSIS TEARS OF EXPOSURE TO DIAGNOSIS YEARS OF EXPOSURE DATE OF DEATH KISTOLOCICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAR PIER IIJCJIMGIITS 16 OTHER COMMENTS 24.05.19 00.12.56 10.01.76 56 15.02.12 RP St Fona 00.01.A] 12.08.76 66 21 IF 16.OB.14 peine Brlgnoud 09.02.99 00.05.79 65 19.01.31 Solvay Tavaux 2i.04.63 26.06.79 A0 30 05-0A-2A Chloe ChlmJe (Eurme r I y HP) St Fona I9A3 00.(17.81 57 38 21 JO.01.78 91 tl.M.76 27 23.06.79 Ye. 13 22.08.79 Tea 36 29.07.8J HUH High Autoclave cleaner 10 yra In mechanical engineer!ng lndnat ry 1946-1956 1941-1966 polymer- laatlon gcncral purpose worker 1946--1972 VCH syntheilt Old 4 Acetylene) Foreman {.gent de maltrlee) mi---------- ret 1 red Died of pu1nonary embollam 5 days after aurgery High Very High 1943-1975 ami h*l el ml 11 cut 1 y 1975-197V Monomer production and polymer* I eat Ion operator Aucocleaner 2 yra a* cycle Cigarette 2 yr, median f c. amnker unt11 Autu- 10 yra as 1974. Ill all operator enamel ter In of 1977 due to 9 yra. sanitary ware Oesophageal Copolymer* A yra manufacture vac tree. Surgical InterveneJ no 25.05.79 (right he [i.l1crlony) 1943-1975 1975-1979 Al I t ypea of m.i I 111.... . I |ohs on wot k n.niiit nr | tire 4 m.i lui t'inmre In VCM poly I'mrviir. I SENC QQS5?2 IMPERIAL CHEMICAL INDUSTRIES LIMITED PLASTICS DIVISION LIVER Aiigluearcona Case! - (Review Date; 1 Jan 1984) franca Sheet t. Peg* # HU11' OR INITIALS DATE OF BIRTH COMPANY FACTORY FIRST VC EXPOSURE DATE OF DIAGNOSIS 03.01.37 Chloe Chlnle (formerly M) SC Fona 07.07.53 26.09.82 13.07.22 Chloe Chiml* (Formerly *P> St Fona 27.10.41 05.01.83 22.02.23 Chloe Chimle (formerly RP) St Fona 17.06.46 03.04.63 ACE AT DIAGNOSIS 45 61 60 YEARS OF EXPOSURE TO DIAGNOSIS 27 41 34 1 l 12 n 15 YEARS Of EXPOSURE DATE OF DEATH histological CONFIRMATION I ESTIMATED 1 EXPOSURE | OCCUPATION LEVEL ( OTHER CAREER HIGHLIGHTS OTHER COMMENTS ,, <jGT> Yea 3fl 03.04.83 Yaa I 1 1 High-20 yr |Autoclave Moderate (cleaner 7 yra 11955-1962 ]autoclave (operator 11962-1962 J________ \ Uigh-33 yra(Folymerleat- Moderate- (Ion Proceaa Low - 5 yra|Kan I lMaintenance (Worker I |Health 6 (Safety Agent ___________ 1_______________ l High - lAutoclave Other aectnra 23 yre lCleaner of St Fona |1946-1971 1 l I t 1 Factory 1971-- 1978 J C G>ntastofc Leccer of 5 LO 1983 Retired Jan 1979. J C Contaaaot Letter of 5 U) 1983 Ru tired 01.01.79 J C Contaaaot tetter of 5 10 1983 I 1 1 QENC 008593 Y AND ENCE NAME Of INITIALS DATE OF BIRTH IMPERIAL CHEMFOAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION LIVER Anglnaarcoiaa Caae* - (Review Date: | Jen J9B4) Gereuny Sheet 1 Page 9 10 11 13 H 15 FACTORY FIRST VC EXPOSURE DATE OF DIAGNOSIS ACE AT DIAGNOSIS YEARS OF EXPOSURE TO DIAGNOSIS YEARS Or EXPOSURE DATE OF DEATH HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS 16 OTHER COMMENTS 1t i i 2i i i 1i i i i i i i i i i i i t i i i i i i ,i l 11 1 1 1 (00.00.30 i Dynaelt |Troladorf | 01,10.56 | 19.09.63 1 38 1 12 \i 1f 1 1 1 ii 100.00.31 i Dynanlc k1 i 1 |Troladorf1 14.10.57 1 IS.09.70 1 39 1 l 13 1! 1! 1 1 1 1I 11 1 1 1 100.00.30 1 Dynaalt \Rhelnfel~| 09.06.51 | 00.03.73 1 41 1 21 1l |den | i 1 I 11 ii i 1 1 1l ii i 1 1 1t ti i 1 l ti ii i 1 1 ll ii i 1 1 1l it i 1 l 1t it i 1 1 tl ti i 1 1 1i ii i 1 1 1i ii i 1 1 1i ti 1l 1l ii v 1 1 1t ti i 1 1 l1 ii i 1 1 11 ii i 1 1 l t ii i 1 1 \1 100.00.30 l Wacker i Hat*- ii 1 | 16.04.57 1 16.11.74 1 44 1 1 17 hausen i 11 1 i ii 125.01.69 | Yea (NIOSII) 1 11 iPolyworker { i i i 11 1 i li 1 i U 114.11.71 |Ve. (NIOSII) 11 11 IPolyworker J i i i i 11 1 i 11 1 i 16 110.10.71 (Yea (NIOSII) 1 i i irllllni i i 1 i 1 lReported unth i 1i 1 Ipeatlctde | Inon jnjiy*er- i 1i l laeroNol canal l taetIon i 1i \with VC \ |worker* In i 1i 1i i 1 NIOSH Hat ol i 1i 1i i 131.1.77. i 1i 1i i |Tht* of cuur i 1i i 1i 1t 1i i i Ha *tr letly |correct. i 1i 1i i 1 However t i 1i 1i i 1 wonder i 1i i 1i 1i 1i i i (whether thla |maii had high t 1i i 1i i 1i 1i 1i 1i i i i |oA|>u*ure to 1VCH in his lean Hiking t li 1i i (operation! i 1t 1i t 1 i 11 l\ I 1 i 17 125.11.74 | Ye* (NIOSH) 1100-500 PP*t Poly worker A|I95B va* (ClIntcal but high temporary autucleaner dela U In during 1 yr autocleaner for 1 yr paper by autocleaner Cokel et al Virchow* Arch A Path 1976 J72 p 196-201 6ENC 008594 IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION LIVER Angloearcom* Cuaea - (Review Date; 1 Jan 1980 Cermany Sheet 2 Page 10 10 11 12 n u 15 16 AND NAME OR DATE OP CE INITIALS 81RTH COMPANY FACTORY FIRST VC EXPOSURE DATE OP DIAGNOSIS ACE AT DIAGNOSIS YEARS OP EXPOSURE TO DIAGNOSIS YEARS OP EXPOSURE DATE OP DEATH HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE | OCCUPATION LEVEL 1 OTHER CAREER highlights t l 1 1 1 lve*1 06) i | | | | | \ 1 1 i i Rive 05) __!1 , ------------- il ii i1 ii i1 100.00,36 l Hoechet 11 IPrankfurtl 02.04.60 1 10.12.73 1 1 1 1 38 1 1 1 1 13 \| ii 11 1| ii 11 |1 ii 11 |1 |i )| t| 1| 11 1| || 11 11 )| l J1 |1 |1 |1 li I1 || i1 | |i || 11 li 11 1l 1i ii 1 |i |1 11 1i ii 11 Ii |1 l ti ii l1 1i it 11 1i 100.00.32 f Lome ii l 1U.ld.hut | 16.12,62 1 00.00.73 1 63 1 1 13 1 ii 1 1 tt 1 1 1l 1 1 05 116.12.74 |Yea (NIOSU) l i ii i ii 1 1 i ii 1 i ii 1 i ii 1 t ii 1 i ii 1 i )i 1 i ii i ii 1 1 i ti 1 i ii 1 t ii i ii 1 t i ii 1 l ii t i ti 1 i ii l ii 1 12 109.01.75 | r.i 1 1 1 00.00.26 Wacker Burg* hiuaeti 15.06.54 12.11.75 49 21 21 13.11.75 Yes (KIOS1I aye 12) 11 1 k |BG Cheat e 1 i | |..y. 1 1"cheatatry 1 |labor*torian| ]In the JTecItno- l 1 1 logical | IReaeerch | lDepartment" | KNIOSII y I ]eeel*tnt | (factory | Ichemlat 1 (which may bl (wrong 1 |tra#lation)l ti ii ii 11 1PVC - Monu- 1 Ifacture |Shift Latde I J__________ I 1PVC Menu- 1 lecture and 1*11 work llncl euto- IdeanlnR 112 yra 1(1954-66) (Foreman Tec |Dev yra 1(1967-1975) 00.00.17 Dyne*It Trolador 19.07.34 06.04.73 58 20 20 25.12.75 I __ I IPolywurker 1 1 1 I OTHER COMMENTS 1 (Confirmed 1 1 (Reported tinder 1 lium-pul yracr- | | teat Ion 1 Iworfcera In I imosil ll.t of ' (31.3.7) and 11.76. 1 don11 l think thU U (a correct (claaelfLcatlon |hy NIOSII. Thr |wan may have (been Involved (In VCH 1polymerlBat 1 or |ln pilot plum |or In malit 1 plant. 1 i i GBMC 008595 AND NCE HAME OR INITIALS DATE OF 81RTH IMPERIAL CHEMICAL INIHISTR [RS PLC PETROCHEMICALS AHI> PLASTICS 0 VISION LIVER Ang Losurcoua Cases - {Review Da L Jan 1984) Germany Sheet 3 PaRts H to 12 13 14 FACTORY FIRST VC EXPOSURE DATE OF D f ACNOSIS ACE AT DIAGNOSIS YEARS OF EXPOSURE TO DIAGNOSIS YEARS Or EXPOSURE DATE OF DEATH HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS 16 OTHER COMMENTS :lvca U) 1 1 ivea| 10)1 ) t l 1 l 1 00.00.34 Marl 20,02.6| 16.06.76 41 13 24.03.78 00.00.36 CU1I 01,01.61 00.01.77 40 16 10 07.03.77 High peak* 12 yr* poly- worker incl |7X auto clave cleaning Control room 1 yr High peak* 10 yra polyworker Incl 17X auto clave cleaning 11 it i 1 1 J00.00.29 t Wicker 1 Burg- l 10.10.35 i 18.08.77 1 47 1 21 i1 |hauaen ] i 1 1 i1 ii i 1 1 i1 it i t 1 i1 ii i 1 1 t1 it i 1 1 i! ii i 1 1 i1 100.00.38 l Dynaalt t1 i 1 ITroltdorff 00.00.61 i 00.10.77 1 39 1 1 18 1 i1 1 22 128.08.77 1 1 11 1 [1 1 11 1 11 1 11 t t. 1 1 11 1 6 107.10.77 1 Yea tea i i High i i i i i i i it ii 11 yr. uto- i |c)av i J cleaner 119 yr* If liter i i i (operator i 1i \i IfVC Kamifacture i Autoclave worker for 6 yr* Ml/78 Cimf I TMHfU Average expuaure f J mi 9 yra 150 ppn,, occ 100(1 p|. Next 5 yra av, 75 ppm, l.uat. yr av 15 ppm Average exjtoaure flrat 9 yea 150 pp**, occ 1000 ppm. I.aat yr av 75 ppm. CWH letter of 21.04.78 i i i i i i i i i i GENC 008594 IMPERIAL CHEMICAL INDUSTRIES fl.C PETROCHEMICALS AND PLASTICS DIVISION LIVER Angiosarcoma Cases - (Review Usee: l Jan 1934) Ccnaany Sheet 5 Page (3 10 12 13 U 15 16 AND NCE NAHE OR INITIALS DATE 0F BIRTH COMPANY FACTORY FIRST VC EXPOSURE DATE OF DIACEJOSIS ACE AT 01 ACNOSES YEARS OF EXPOSURE TO DIAGNOSIS YEARS OF DATE OF EXPOSURE DEATH HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS OTHER COMMENTS give# 15) 00.00.37 Dynaalt Troladorf n.6i 14.08.73 16 20.08.76 Yea High Autoclave worker 00.00.13 Hoeehst Cendorf 00.00.55 25.12.79 66 24 21 25.12.79 Autoclave Worker l \ 1 )AngInaurcnaa | con tIraed. ] Animal report |of the North ] Rhlne (Westphalla |Mollcal |Inspectorate |for 1973 Ipagc* 347-377 Iglvea full |Jetatla. Vinyl t chlorlJe (dlacnxe |d1 agnosed 102-02-7), 1 Oeao phngcaL IvttCIces. I Radlolugleal1j 1 confirmed ocri. |oaten!yaI a, 00.00.25 Dynaalt Troladorf 18.10.54 00.08.79 54 25 IS 22.02.60 Yea High Anted a Ketaataalng Worker ASL )Dr Beache Heller of |k 3-04-B2 to (Dr V C F Ada 00.00.15 Dynaait Troladorf 14.02.61 00.04.80 65 19 13 19.10.80 Yea High Autoclave | Dr Seaehe Haemanglo Worker |letter of Enriothellone |L3-04-82 to of liver with |Ur W G F Aila Hetaataaea I I 1 |00 00.13 | Dynamlt ITrol.dorf] 01.01 61 1 00.09.79 i 66 1 17 1 n 119 .06.60 | Yea 1 High* (Autoclave i (Dr Bcaehe 1 1i 11 1 pronounced i 1 1 i (Haemangio | |Worker and * (letter of l ti 1 1i 11 1t (clinical 11 lver t i 1 1 l 1Endothellout 1 1 [ (of liver with | (worked In i (drying shop i m-(H-82 til | Dr U V K Ait-ias 1 1i l1 1ayutoma) i 1 1 i ^Metaataaejy 1 t i 1 1i 11 1 i 1 1i ii 1 00.00.21 Dynamic Troladorf 15.10.61 17-09-80 59 06.12.81 | ! High Autoclave )Or Itaucli fld .la?ft* J Wot Vur uoh> iMjuunt I y 11utler of txst:------------ Kon 11 V (14- 82 t< _______ Y Adam* 0EHC 008597 IMPERIAL CHEMICAL INOliSTR 1ES PLC I'KmCIlF.HSCALS AHH PLASTICS D VISION Germany Slice t 4 F*ru 12 LIVER Angiosarcoma Cases - (Review Da 1 Jan 1984) 10 I n u 14 15 I It AND NAME OR DATE OF CE INITIALS tURTIl COMPANY FACTORY FIRST VC EXPOSURE DATE Of DtACNOSIS ACE AT DIAGNOSIS YEARS or EXPOSURE TO DIAGNOSIS TEARS Or EXPOSURE DATE OP DEATH HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER IUUH.ICHTS | | | OTHER COMMENTS ________________ I I 1 00.00.14 Lons* VatdabuC 00.00.60 09.04.79 61 14 19.05.78 Yea l |P U Rent |letter of IlOrh June 1980 lend ruing dnta l from I Mr H p Frledel Not an Angiosarcoma In hte letter of 21 12 91, Mr Fried*! lot BQ Cliente |F u Rest | let ter uf 110th June 1980 June losing d.aa I f rom aid this was a "Platteneptthel karzlnoai Der Spelaerohre" (a carclnoaia of the Iff P Frledcl of |EC Chumle (withdrawing (this case I 1 oesophagus) not ettrlbut- able to VCH 6 not recognlaed as an Indust rial disease 00.00.29 Hacker Burghaueen 19.10.53 "ooTToTTF 49 25 21.10.78 Yea Autoclave cleaner and worker. Drier operator. Later shift leader 00.00.23 Dynaslt TrolsJoeT 10.01.55 0**08.78 55 21 20 of.06.78 Yes High Autoclave (Leibach ASL and worker till suspected Hepatocellular 1964. ASL at Card nooa Leader and Feb 1975 master laparotosy) GENIC 008598 ]Angiosarcoma |conf1 rued 109/79. Some Idetall of this J6 also cases 19, 11, 15, 16 |6 17 given In \NRW Report for 1 1976 _____ 1AagJotnrcoma Icon!1rmed, (full details Jof Illness 1stnee March J197 1 x I wen I n [NkU Med Iiiw|> (Hep (f)r I97H. |Mil Icruut | d lt| nits g I wen Mu "vc |Adam" Inted |I118c.j,si:` \>y Mrlh.nh and IM.nf.U-1 I Of M I'JHO p/l . AMD HAHC Oft DATE OF C INITIALS BIRTH COMPANT f IMPERIAL CHEMICAL INDUSTRIES PLC HETHUCMEHtCALS AHU PLASTICS DIVISION LIVE* Aitglossrcona Cases - (Review Date; 1 Jon 198M Tors 16 10 U 12 13 P1KST VC EXI'OSURe DATE OF DIAGNOSIS ACE AT DIAGNOSIS TEARS OP EXPOSURE TO OTACNOStS TEARS OP EXPOSURE DATE OF DEATH IIISTOLOCICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS OTHER COMMENTS 23.12.IS Norsk Hydro Kerojr* 00.03. SO 21*12*71 S6 22 04.01*72 Yes ^Mgh Vor.M.n fc Autocltve .upervl.or l | 1 1 l 1 t 1 1 1 1 1 l 1 1 | Cuitf t raed by 1 Dr TLJIs| Evsniten of Ml lAt APKE Htg < 19 June 1978 iKr P Rangoes letsted that > fliaj been a laenbur of a )ntAft-up tea* 1VCM 6 PVC wcr (*a<le In woi Ihul LI tug. Tt fVCH was nadc Ifros aceiylei SENC 008599 IMPERIAL CHEMICAL INDUSTRIES PLC PKTKOOIEMICALS AMD PLASTICS D VISION LEVER Angloearcoiea Cases - (Review Da 1 Jan 1984) Page 17 10 n u n 14 5 NO NAME OR DATE OP E INITIALS BIRTH COMPANY FACTORY FIRST VC EXPOSURE DATE OP DIAGNOSIS ACE AT DIAGNOSIS YEARS OP EXPOSURE TO OIACNOStS YEARS OP EXPOSURE DATE OP DEATH HISTOLOCTCAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS 16 OTHER COMMENTS 2 3.06*27 Kemanord Sundaval1 14*08.51 20.10.70 43 19 18 20.10.70 Polymarker 27.lt.1t Kemanord Sundavatl 00.01.45 00.08.72 61 27 27 16.08.72 tea '*lgh VCM production 1 | AL i i i t t i i i i i i i i i i 10.06.10 Kemanord Sandavail 00*03.47 18.03*76 65 29 t1 ii i i i I16.ll.tt l Kemanord |SundavalL| 00*00.46 i 12.05.77 i 62 i 31 11 ii i i i 11 ii i i i 11 ii i i i 11 ti i i i 11 ii i t i 11 ii i i i 1t it i i i 11 ii i i i 11 ii i i i )l it i i t 11 ii i i i 11 ii i i i 11 ii t i i 11 11 i i i 112.03.19 1 Kemanord ISundaval1| 11.05*64 i 22*11.80 i 61 i 16 21 19.03.76 t 11 1 31 111.05.77 1 l 11 1 11 1 11 1 l1 1 11 1 11 I 11 1 11 1 11 t 11 1 11 1 11 I 11 1 11 1 16 122.11.SO 1 Yea Yea Yea High Polymarker i 1 High 1 1 l 1 1 1 1 1 1 1 1 1 1 1 High ~ 6 Years tow 10 Years 1 119*6-195# 1 poljnwr- 1 1 l llaatlon \ Iworkcr (12 I lyr.) 6 1958-1 11977 foreman! 1(19 ym) 1 11 11 11 11 11 11 1t 11 11966-1970 1 centrifuge operator 1970-ivan drier operator Hr SJoelln'a letter of 28 March 1978 confirm* RL was a monomer worker who wa> heavIIy exposed, probably even more so than u normal reactor cleaner 1 Jin first 12 lyre of |employment had |buen licav] 1 y |exposed. In 11974, 11 vie r |abnormalIty land necrosis J! 1 jgnoried. |l>ata confirmed |In Dr D Syren Jletter lfl.8.77 Ito CEP1C 1 i letter of 2nd Nov 1981 fri Dr J)avlJ llyre letter uf let April 1982, Dr Mt/tewno of JAKG tya l Sweden'h National tUioril of OS Health gives 20-02-70 aa rfute ol dlaguotrla fnr C<nm 0| and JWIV'72 /> ILiat* 07 GENC 008600 I IMPERIAL CHEMICAL INDUSTRIES Pl.C PETROOIKHICAI.S AND PLASTICS U VISION LIVER Angloaarcoma Cate* - (Review Da ej ] Jan 1984) UK Sheet I Page Ift 1 1 ii 1 1 1 12 i ]t 4 ti t6 1 7 1 81 1 t1 9 1 10 l ii 1 i1 1 12 i 13 1 14 1 15 1 1 J___________ L 1 1 t 1 l| t1 1 11 AND | NAME Oft | DATE OP 1 ret | INITIALS | BIRTH 1 COMPANT ll t 1 1 1 11 i1 ( l l MUST VC 1 DATE OP 1 ACC AT 1 TEARS OF 1 YEARS OP | DATE OP 1 HISTOLOGICAL i CSTIHATED 1 1 | FACTORY | EXPOSURE 1 DIAGNOSIS 1 DIAGNOSIS 1 EXPOSURE TO 1 EXPOSURE 1 DEATH 1 CONFIRMATION i EXPOSURE | OCCUPATION | OTHER CAREER i 1 ii 1 1 1 DIAGNOSIS 1 it t LEVEL i ( HlCHMCttTS i 1 fi t I 1 1 i| ii 1 i 1 ii 1 1 1 1 i1 ii i 1 ii l 1 1 1 i1 ii t i 1 ii 1 1 1 1 i1 ii i |UJ 120.04.01 1 ICI |Hlllhouael 04.04.44 1 03.12.22 I 7J 1 2B 1 22 103.12.72 1 Tea i ^500 pjm 11944-7 VCH i 1 11 1 (Fox 4 1 1 I l(Fox 6 1 i 11947-S Drier) 1 1 11 t Collier 1 1 1 (Collier 1 i (1948-61 i 1 1 11 1 paper a*ya| ( 1 (paper 1 i (Autoclave t 1 1 l1 l 23.1 2.72) 1 1 1 l**y* 1 i (operator i l l 11 1 1 1 I 121.12.72)1 i 11961-66 i 1 1 t1 1 1 1 1 11 i |Drier i 1 1 x 11 1 1 1 1 11 l 1 1 1 11 1 11 i\ it i t 1 i 11 1 1 1 11 ii i 1 i i1 1 1 1 1 t1 ii i 1 11 11 1 11 ti i 1 JL _L 1 ( 1 1_ 1 ii i 1 1 BJU i 102.06.32 i BP ii i t 1 1 Urr* t 00.02.66 i 00.1 2.74 1 37 1 09 1 1 3.5 t1 124.12.74 1 Ye* ! 1 High 1 |Autoclave i i i i 11 i 1 1 1 11 1 (cleaner i i i 11 i 1 1 1 !t tt i i f IJSK ! I 123.06.20 l ICI JL \ 1 1 11 i 1 1 1Klllhou*e| 26.04.54 i 00.06,79 1 59 1 25 1 11 1 11 1 is 112.10.79 1 Tea !i ii i Medium- 154-5 i 1 iPm-var flah i l ii t 1 l 1 11 l high |Bugging |packer ( l ii i 1 1 1 11 i 1 Flint 11939-45 ttmy i 1 it i 1 1 1 11 l 155-6 (vehicle i 1 it i 11 1 1 l IDrtec Plant (maintenance i ( ii i 1 t 1 11 i 156-58 11945-54 i l ii i 1 1 l 11 1 |Autoclave (fish packer i l it i 1 I 1 11 l (worker i i l ii i 1 1 ) 11 i 158-61 i i 1 it i 1 t 1 11 i (Chargehand i ( l ii i 1 1 1 11 i |Drier i t i ii i 1 1 1 11 l (Plant ! t l ii i ( 1 1 11 t 161-72 t i t ii t l 1 11 i |Foreman 1 i l it i 1 1 1 11 i )C 2/3 Flint 1 i i it i 1 1 l 11 i1 1 i l ii i 1 1 1 11 i1 1 > i ii i 1 1 1 11 i1 1 1 1 16 1 i ( OTHER I COMMENTS i i i i i tl.ee iml ll.rrr 1 Lancet 129-06074 Ipagea 1M6-U i t i i i I Dub Iona 1 fahrlCrttIon (c aae 1 1 1Empoaure (limited to 12.66 - 9.69 1 'l l 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 i t ii i 1 1 11 i i ii i 1 1 11 i i it i 1 1 11 i l ii i l 1 1I i i ii i 1 1 11 i1 i1 i1 i1 !t t 1 t 1 1 1 1 GENC 00860 12 ii 1i AND t NAME OR | DATE OP NCE J INITIALS | BIRTH j i UK i i 130.03.1* CEP 1931 ft os 26.04.20 4 15 COMPANY | FACTORY BP |S.rrjr Berry Berry 6 FIRST VC EXPOSURE 08.01.SI 1962 1963 IMPERIAL C1IEM CAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION OK. Sheet 2 LIVER Ati* Obicona Case* - {Review Date: I Jen 1984) 7 DATE OF DIACN0SIS 00.10.79 09.01*80 00.00.80 a AO.P. AT DIAGNOSIS 65 48/9 60 9 YEARS OP EXPOSURE TO DIAGNOSIS 18 J7 10 1 11 1 17 1 13 ( !* 1 11 11 1 YEARS OF 1 DATE OP 1 iriSTOI-OCtCAL | ESTIMATED 1 1 EXPOSURE 1 DEATH 1 CONFIRMATION | EXPOSURE 1 OCCUPATION | 1i 11 21 119.11.79 | i LEVEL i ii i 11951-52 i i 1 1i i IPolycleener | 1t i 11952-55 1 i t I Latex | 1955-60 Polyfloor 1960-64 Poly Chergehand 1964-70 Charging operator 1970-71 Drier operator 12 09.01*80 82 t 3*06.80 7 yra Poly floor Operator 5 yre Cceeeer on Poly Floor Polycleener * 1)963-5 Recovery 1965-1971 15 OTHER CANKER mom. touts 1 1 1 1 1 1 1 1 1 1 Page 19 16 OTHER COMMENTS VTH 08.06.24 BP Berry 19.09.50 27 1950-1958 500 p|*a , 1968-197* 200 ppm 11950-51 1 1938-19*8 1 Autoclave (Motor Mechanic loperetor 119*8-1950 11951-1957 lOimratur on tChargenen |Acetylene | autoclave (Product 1on 1 building |Plant 11957-1974 I Shift p ]eupervlaor i lautoclave i |bnJIdlng - i (Never Jcleaned i i laiitoel avee i 1 but i | aupurvl aor* i) 1Job entailed| Junior Iur f teulnr I uvea | 11 u ) Ubpia 1 GENC 00860 AND ICE NAME OR INITIALS DATE OP BIRTH 07.05.25 Barry IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION LIVER AngEoaarcoiaa Caaea - (Review Dace: I Jan 1984) UK Sheet 1 FIRST VC EXPOSURE 15.02.50 DATE OF DIAGNOSIS 02.05.83 ACE AT DIAGNOSIS 5B YEARS OF EXPOSURE TO DIAGNOSIS 33 10 I H YEARS OP EXPOSURE DATE OF DEATH 29 24.02.S3 TF TT TT 15 HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS Medina Polyworker 2 yeara on Acryl onItrIle Kealn Plant. Also jrlor to 1950. 4 yearc HAP nil ntenance . 3 yeara Motor car palntahof) 2 yeara In Craving Dock. Page 20 16 OTHER COMMENTS I GENC 008603 _____ i__________ IHPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS ANI> PLASTICS 0 VISION LIVER Angloeurcona Cases - (Review Da e: I Jen 1964) *l)t ayitca of dates DAY - MONTH - YEAR USA Sheet l Page 21 ' AND 'MCE NAME OR INITIALS DATE Or BIRTH 10 12 14 FIRST VC EXPOSURE DATE OK DIAGNOSIS ACE AT DIAGNOSIS YEARS OF EXPOSURE TO D1ACN05IS YEARS Or EXPOSURE DATE OF DEATH UISTOIjOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS J6 OTHER COMMENTS Earl Parke 17.10.23 Louie-' 09.12.48 03.03.73 49 24 21 03.03.73 villa 19.08.33 Edward 25.U5.15 Dinwiddle Louis ville 15.11.55 00.05.70 37 14 27.09.71 (MLOSH aays 26.09.71) Loula- 26.tl.45 19.12.73 58 28 28 19.12.73 vllle 15.01.24 Louta ctile 06.07.52 19.06.67 43 15 07.01.68 Yea 25.01.12 6FC Louie- 19.06.44 09.04.64 52 20 20 09.04.64 villi Ray 23.il.2B BPC Louis 17.01.62 00.02.74 45 12 12 24.07.75 Austin ville Jones! Charles T Smart 03.05.22 UCC S Charle 27.08.44 ston 00.00.68 45 24 17 23.03.68 Pot Cleaner (Block Jane 1974) p 53 Ilia Lory given Rolling Stone In Annale NY Art ACAD SCIENCES Ref l NY Arad VoI 329 (1979) of Sc Syep page 190 In 1974 Paper by Aleo Block B R Gottine of Jana 1*7.7 4 OSIIA P 53 Pot Cleaner (Cf Block) X* f 1 Also Block JAMA 1.7.74 P 53 pot Cleaner (Cf Block) l.oulavll le Courier Jon mill 02-09-80 Pot Cleaner (Cf Block) Ref 1 Also Mock Ref I Al ao Block Pot Cleaner (Cf Block) Ref I Al ao Block US Air Force Pot Cleaner (Cf Mock) Kef 1 + r.outsvl t le Time* 23,7.75 Retired April 1974 Aleo Block Ref 06.05.20 Coudyear Hiagara 07.10.46 00.08.61 15 29.08.61 Yea 6ENC 003604 IMPERIAL CHEH1CAL INDUSTRIES PLC PETKOCMKHI CALS AND PLASTICS DIVISION LIVER Angloaarcoaa Caeca - (Review Date: 1 Jan 1984) *VK eyetem of dates DAY - MONTH - YEAR USA Sheet 2 Page 22 10 12 13 14 15 Y AND ENCE NAME OR DATE OP INITIALS BIRTH COMPANY PACTORY FIRST VC EXPOSURE DATE OP DIAGNOSIS ACE AT DIAGNOSIS YEARS OP EXPOSURE TO DIAGNOSIS YEARS OP EXPOSURE DATE OP DEATH HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION CITHER CAREER HIGHLIGHTS 1 | 1 \ OTHER COMHRNFS I Raymond CettlePI iigafT 08.1 1.31 Lflulivl lie 26.05.45 01.03.74 43 2V H.03.75 Yea 2000 pp*t 1 IRef l ha* |wrung figure! |re flrat |expoaura. | l.oulav 11 le tTinea 129.10.74. M2.3.75. 110.3.7b 16.08.13 Coodyear Niagara 12.06.51 00.05.68 55 17 17 10.05.68 I IRef 1 I 27.05.09 Coodyear Niagara 14.10.46 00.03.70 61 23 23 16.03.70 I 1 Francla A 7.11.16 Flreatone Pottetovn 13.07.49 02.05.69 50 20 19 02.05.69 Yea High 10 yre 10 yre aa Utility 4 |Ref I + tetter Bachaan Pa reactor op. Service op. |of 26 April (not cleaner Bagger |I978 fro* - separate Dryer op. IRuseull A Park crew cleaned Stripping op. |lo .1 T Sc awe 11 autoclave*) 3 yra prior |of HCA service In tyre plant I 1 Richard 12.21 ucc 5 Charle 11.12.42 00.05.74 52 32 26 07.04.74 Edward ston Clendenln 2000 ppa | Charleston |Dally Mall 121.7.75 J_________ I 1 Dubious |f abrlcatIon leave I I | Dubious 1 f ahr l cat 1 | r.itu* 1 GEHC GO8605 LY AND ItNCE J NAME OR INITIALS DATE OP BIKTII COMPANY IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS f) VISION LIVER Angiosarcoma Cave* - (Review Da e: I Jan 1984) * UK Syatee of dates DAY - MONTH - YEAR USA Sheet 3 Page 21 10 12 n u 15 FIRST VC EXPOSURE DATE OF DIAGNOSIS AGE AT DIAGNOSIS YEARS OF EXPOSURE TO DIAGNOSIS YEARS OK EXPOSURE DATE OF DEATH HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS OTHER COHHKNTS Jaaei Howard 04.1 1.27 Loulavilla 08 .05.50 00.00.69 41 19 Peercnboo* 06.05.31 Louiavllle 23.06.55 IL .10.74 43 19 \i 8 (Charlie 122.04.28 i BKC I Arthur i ii ii ii ii it _j jt ii 9 IVlrgll 100.00.15 i UCC 1 Christlan i ir i 1 1 |Avon Lake] IS.09.54 i 00.00.75 1 46 1 21 ii i t 1 ti i 1 1 it i t 1 ii 11 ii t 1 1 ii i 1 1 !i i 1 1 1i i 1 1 IS Oi.Tl.-l 00.00.43 i 19.06.75 1 60 1 37 I aton t i 1 1 31.06.17 Goodyear Niagara 00.00.55 30.01.76 Cheater Hinkle 02.09.09 UCC S Charie- 00.t2.46 ton Early 77 58 67 30 04 27.03.69 Yea 1951-4 VCM polyeerI sat Jon Rron 1954 Table 4 In onwards In Wagoner Arey and other Testleotiy to BvrvIce. US Senate 46-50 Ariay CoufI reed in H N Johnson Ur 07.08.78 16.10.BO Yea on I I .10.74 but no poat-mortee 16.10.80 1 11 1 13 102.11.75 1 1 11 1 11 1 11 1 11 1 11 l t1 1 11 1 1l 32 106.04.76 1 1 11 Yea Yes i 113 yr. i IN.v* 1autoeleaner| |B jrr. on | lEetol ITyre Store IplaatJeteer| |t Carboaet | |oprat Ion l i i 12000 pp. i i 1 11 i | | 1 1 | \ | i i | 1 Dr M N Jnlmaon letter of 24.2.81 conf t reed death 6 year* after d I nvnoa 1 Confirmed In |H N Johnson lltr 07.08.78 |Also Aolling |Stone eaft. 115.01.76 t i 1 | V1111aeaport ISun Gazette 21 June 1975 Charleston Dally Hall 21.7.75 18 30.01,76 22 02,01.77 Yea N10SH letter of 25.10.79 28 yra with UCC at SC Ret I red Nl'UK lL`lcUtC 2 1.2.77 GENC 008606 IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS ANI) PLASTICS D VISION LIVER Angiosarcoma Cases - (Review Da 1 Jan 1984) system of datea DAY - HONTH - TEAR USA Sheet A Page 24 10 12 14 16 AMD JCE KAHE OR INITIALS DATE OF BIRTH COMPANY FACTORY FIRST VC EXPOSURE DATE OP DIAGNOSIS ACE AT DIAGNOSIS YEARS OF EXPOSURE TO DIAGNOSIS YEARS OF EXPOSURE DATE OF HISTOLOGICAL DEATH CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS 16 OTHER COMMENTS 02.10.23 arc Loutsvllle 11.07.47 00.01.76 52 29 Chariaa Edward Moore 00.00.23 7.05.17 Great American Chemical Company UCC Fitchburg oa.09.58 "SOOT Maas. S Charieaton 1939 27.05.77 ~W 60 38 it f rom reg mud |ii K Kjinlttukl let cr of 5 Hovt wber I 9 Hi) 28 OA.12.76 Yea TT oOTTTT Yc. Lmilav lUe T1me a 26.1.7b said He vai the 10th AS vlct! at Re 11 a l*atie ol whue E had died bjr 26.1.76 In hla letter of 16.09.Sl Or H N Johnau confirm* this la t lie caae describe by Dauntiher Tamburro A Ye In Feb 191*0 A* J Medicine Vol 70 p2BO 241 (HIOSH aaya 26) 27.05.77 Cholangloitrcuaa (R Kamtnskl 26/2/79) Medium to high for 2A yra 6ENC 1941-65 non- 1937-39 via N H Wheeler olvent off and on vinyl reein I about*r unit end 1939-41 may latter of 18.8.77 to J Stafford disperelon have been vinyl reelna exposed aa gives detail* Rose KantukVI unit first reactor letter of aa fitter cleaner helper, then 1943 became Lift shift fitter 26/2/79 R Kaminski (5 Nov 1980) utility man 1946 became anggesta that ablft utility NT0SI! will nan retain on 26.04.66 register nine employment wan this neopl am* t ermliiftt ed ay be uaaocl at eel wj th ASl, K N Wheeler letter of 00860: 2H/2/79 amt Kn:;o K<*w I ne.k I lei II-is ill ''//(Mil ,-l IMPERIAL CIIKHlCAL INDUSTRIES PLC PKTKi HJIIKMI CALS ANN PLASTICS l)| VISION LIVER Angloaereoaa Cases - (Review Date: 1 Jan 1964) *UK *yste of date* DAY - MONTH - YEAR iisa Sheet 5 Pag* i i: 3 l AND 1 NAME OR OATfi OF NCE | INITIALS 1 BIRTH i i l.lohn berry 07.07.23 1 l 1 1 ( 1 l l 1 1 1 l 1 J (J L 1 Forre at 11.64. It i i i i i i i 1I.04.W i i i 12.10.07 i i i 1 UVN 22.0^.22 i i i i i i i i ON.11.23 i 4 COMPANY ii 1 3t 6 )1 1 1 FIRST VC | FACTORY | EXPOSURE ii ii ii BFG | Lou la- | 03.10.*7 |villa J ii ii ii ii ii )3 11 11 11 11 11 11 UCC 11 1S Qiarle-| fil.67. i.1 | aton \ ii ii ii it ii UCC ii )S Charle-l 00.0B.44 | aton | i .i tree |S Oiarla-I 00.05.42 | aton \ ii ii Tenneco |Ftenlngton 11.06.64 Chenlcala i i ii ii ti ii ii i UCC IS Charle-| 12.03.66 | aton | 7 DATE OF DtACNOSIS 00.00.77 (up to 2 ye era after death) 30.11 .76 03.11.78 00.0). so 30.12,60 oi.oa.ai 6 ACE AT DIAGNOSIS 57 (death) ii 61 72 56 47 t 9 1 10 j " YEARS OF i YEARS OF | DATE OF EXPOSURE TO 1 EXPOSURE | DEATH DIAGNOSIS \ i i 28 1 JB 111.02.76 (death) 1 t 1 1 1 1 1 1 1 1 1 ) 1 11 3? 1 ii> |15.l i.78 ICN10SH , laay. 27 land C (Dally Mall] 126) 1 1 34 I 33 I03.1I.7B t i 36 1 16 101.03.80 i i ij 1 15 130.12.80 i i i i i i i 36 1 13 102.04.62 1 i 12 i ii 14 i J1 15 1 16 i HISTOLOGICAL | CONFIRMATION | | ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS 1 | \ i OTHER COMMENTS ii i Yea |Expo.ed In Varloua Jobs i IX Kn.Lnskl |aone degree In PVC |letter of (to 22 plant* Iron 126/2/79 and |chenlcat cold roon to 1 Prof. Tawburn (but aialn paate (letter of Jexpoaure recovery to 19/1/79 |vaa to VCM, PVC charging 1 |probably operator to 1 IhlBlr- paate 1 1 charging. 1 1 Ill August t l 1966. 1 1 Terminated 1 1 enploywent 1 1 Jan 1966 1 Yea 1 HigV. Operator to Exposure In | ft N Wheeler 1 10.10.76 bulk and 11 tr of 4 Jan 1 dispersion PVC|1979 and 1 Manufacture |Charleston 1 |Dally Nall 1 130.1 f.7tf and 1 ] It Kami nak L 1 126/2/79 Yea 1 | ft K/mlrrskl 1 (letter of 1 16/6/79 Yea 1 IK Kanlnakl 1 (Letters of 1 119th Juno 19801 1 Yea (6 - Unknown(Malntenance 16 5th Nov 19801 i |9 - Hlnl.al Hechantc i 1 6 yra i t Elsewhere i 1 H yr i l Boiler houae i 1 Operator i 1 9 yra i Yea (High (But Chenleal Fro* L959 to |Dr D.icey (not aa higl Operator In 1976 AlJ phel c| letter as reactor charge Client cm La 16.II).81 and cleaner would experience) Worked aa 1abourer fro* reactor operator . Hid K N Wheeler fro* July 1976 letter of to date 9.11.61. Korenan Also Dr IHcey AT f plot l t c lutler of Clu'wlral IW.U1.B1 re June 1941 Opl'l.tt tun (J j t e of deaf 11. to Kny 19AA ami nay have r htailed GEHC 008608 K'.ichjri, In ilmi ..... IMPERIAL CHEMICAL INDUSTRIES PLASTICS 1)1 VISION LIVER Angiosarcoma Case* - (Review Da l Jan 1964) USA Stiett 6 *UK ayitas of data DAY - MONTH - YEAR Page 26 1 ii 1 2 j 4 i 51 t 1 ! 4H0 | CK l NAME OK INITIALS DATE Or SJRTH COMPANY 1t ]1 1 1 riHST VC I fACTOKT 1 EXPOSURE 1 i1 1 1 ]C U Giroux 2 2-02-06 i ton a an to 11 11 Springfield 15-10-51 1 Hast | i ii i ii 1 ii i ii i ii i it i ii i ii 1 ii i ii i it i ii i ti i ii i ii 1 ii 1 ii 1 -- --i------------- r [ |S Ferguaon 08-10-27 arc (Loulavllle 09-09-54 IJnr ti i ii 7 DATE OP DIAGNOSIS 00-07-79 11-05-82 1 11 t |Mr Ryru. 129-01-34 1 BTC I 11 t 11 1 11 l \1 1 J] 11 109-03-12 1 ucc t1 ILout.vtll* 1955 1 | 03-11-82 11 11 1 1 t1 1 it 1 11 1 |S Charl.-I 23-07-44 | 18-07-83 27-06-92 Hie General Aehtab Tire and HI a Rubber Co 11-06-56 2i-oa-8i a ACE AT DIAGNOSIS 71 54 1 t 48 1 1 1 t 1 1 61 50 t 9 1 10 11 ii 12 i i] 1 14 15 1 16 1 YEARS OF 1 f TEAKS OK EXPOSURE TO | EXPOSURE DIAGNOSIS 1 I DATE OF DEATH t1 l HISTOLOGICAL | ESTIMATED 1 CONFIRMATION | EXPOSURE | OOdJl* AT I ON | LEVEL 1 11 OTHER CAREER LLICIIUCUTS 1 l I t t 1 OTHER comments; l1 28 1 14 17-05-80 An autopay |The death 11940-195! I tin PVC wua done and jeertIflcatelVarIon* Job* (autoclave 1 Mediate ig |ln polymer 1 area) cauae of (Hr Clroux' (manufacture i death given (usual \ BITTVAR i aa }occupation JLUSTKKX i "Angloaarcona*| aa "kettlel1951-1964 i |operator" IVarloue joba |tn 1 In and l I Informal1 on |given In llctter of 24 (February 1987 1 f rum l>r lUalier C |Darned of | Monsanto (Springfield t- i i i i i i i i i i 26 ! 28 J cry Yea 1 t_ZJ 1 |"chemlcala Jlnduatry", i i i i i t i t i i i (around PVC |autoclave* 11964-1973 JVarloua (clerical |Joba in PVC Ipolymerlaatlon If aclllty/ ( Ret 1 red 101-03-73. 1 (Multiple IJob* llncludlng I Ply (Operator + (Or A Minin of \ Muriannto 1 Europe. i i t t i i i IProf Tamburru | let ter of 112 Au 1982 4 |Dr K N Jobneu | Letter of I 28 Feb 1961. t 1 27 1 1 1 1 1 1 39 ) 1 10 ( ve ^tvea + \ \ 1 Poly 11 11965 left RFC (Dr M N Johnai 1 y |Lelomyotareomal (Operator + (to become a lletter of 1 |Autoelave |Clergynan. U Nov 1962 1 t !__________________ !_____________ |Cleaner 1 11 \1955-65. 1 (aud 126 Feb 1981. 1 1 1i i 1 14 |I8 -07-83 1 Ye IHlgh fro. i i |Dr Dacey ) 1944 to | | letter of 11955. | jHedliM from( 15 Kept 19BJ. I | 1955-1958 1 27 27 lj Alive "hYea | Moderate 11956-56 |1abourer 11956-57 I |H W taiindrle ]Ict ter of 112 Svpt 19J (prod helper Jnjvotteil at 11957-70 lr.rJl.fi I ^operator (19/0-75 (H^y I'Ml. I Tv at lug |e lr*rt r feirfn Iriiwncori'il 1 IV/'r-piiTei'fit iM.iy I7K3 |opr i .( or I QENC 00860? IMPERIAL CltEHtcXl. INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION LIVER Angluiarcu** Case* - (Review Date: I Jen I9B4) Page 2 7 1 I 3 I 4 I 5 \ 6 l 7 J 9 | 9 | 10 J 11 I 12 l 13 14 15 16 AND 'fCE NAME OR i OATS OP i INITIALS t BIRTH t ii COWAN* i 1 mst vc 1 DATE OP i ACE AT i YEARS OK i YEARS OP i DATE OF i HISTOLOGICAL i ESTIMATED i 1 l FACTOR* 1 EXPOSURE 1 DIAGNOSIS i DIAGNOSIS i EmiKURK TO i EXPOSURE i DEATH i CONK]RHAT10N i EXPOSURE 1 OCCUPATION 1 11 1 i i DIAGNOSIS i )i i LEVEL 1 1 OTHER CAREER lUUUUGMTS i t i OTHER COMMENTS ttk 05.04.14 Jugo Split 00,00.53 08.04.73 59 20 20 09.04.73 Tea Vlnll 5.11.31 Jugo split 00.00.50 II.07.73 42 23 18 12.07.73 Tea* Vlnii 21.12.31 Jtago Split 04.06.54 il.GI.76 45 22 22 I.01.76 Tea* Vlnll VCH Product ion VCH Production SAR1C et *1 paper Knv Health Perepuct Ive Vo I 17, VP 189-19? 1976 *ln IiIh lette of 3 Oct 1976 L)r Spirt** of N I OSH changed the Mtatna o( t'^*e 02 to VC product Ion employee, Or Spirt an also not J fled h new Cnae 03 also a VCH prnUur1 Ion wui'Vor 11.06.30 Jugo Split 15.I2.5B 03.09.78 49 20 IS 03.09.7S Yea Vlnll Rove Kaalnakl letter of 19th June 198 aii.1 IAKC letter of t April 1992 GENC 003610 ence of ASL Cases Per Annum TABLE 1 (Review Date - 1 Jan 1984) By date of death 1 0 1 0 0 0 1 1 0 2 0 0 1 5 3 2 3 5 7 6" 11 11 9 10 5 10 4 1 4 Total ~103 1 Does not Include Italian 01 but does include German 03. 2 The 1977 total includes US case 24 which is a Cholangiosarcoma. 3 The 1982 total does not include US 33 and 34 who are alive and F 15 who Is alive. 4 The 1983 total does not include US 34 and F 14, who "ro alive. Page 28 GENC008611 butlon of ASL Cases by Country TABLE 2 i (Review Date - 1 Jan 1984) Page 29 any avia Slovakia n 33 *** 21 ** 17 *** 10 8 5 **** l^ Jckirk& 4* 2 2 1 1 Total 108 Omit ItOl - atypical case of PVC bag extruder. Includes GE03 aerosol can filler. Includes case US 24 which was diagnosed as Cholangiosarcoma & US 33, 34 and 36; and F 15 and 16 who are alive. Includes one monomer worker. Includes two monomer workers. Western Europe 'forth America Rest of World 57 43 6 Total 108 GENC 008612 ttern of ASL Cases by Factory TAB.LE 3 (Review Date - 1 Jan 1984) ) W Europe Of the 57 cases in W Europe, 46 have occurred in clusters at 10 factories. Of the 21 German cases, 18 have occurred in clusters at 4 factories. ASL Cases Kemanord, Sundsvall PCUK, Brignoud Dynamit, Troisdorf Chloe Chimie (Formerly RP), St Fons Wacker, Burghausen CWH, Marl ICI, Htllhouse BP, Barry Solvay, Tavaux Lonza, Waldshut 5 5 10 8 4 2 2 6 2 2 46 Page 30 : There are 31 pre 1962 PVC plants in W Europe; 18 of these have had ASL cases (Ref Table 8) ) N America Of the 43 cases in N America, 37 have occurred at four factories out of a total of 49 factories - in N America 39 plants have not had ASL cases. BFG, Shawinigan BFG, Louisville UCC, S Charleston Goodyear, Niagara ASL Cases 10 13 10 4 37 There are 29 pre 1962 PVC plants in N America; 10 of these have had ASL cases (Ref Tables 9 & 10) i Rest of World The 8 ASL cases are believed to be tn 1 cluster of 4 and 2 clusters of 2 cases. genc S613 TABLE 4A .atency Periods (Years from first Exposure to Diagnosis) (Review Date - 1 Jan 1984) Page 31 erica W Europe Belgium France Germany Italy Norway Sweden UK No of Cases 1 17 21 4 1 5 8 57 Total Years 18 438 385 74 22 122 189 1248 Average 18 25.76 * 18.3 * 18.5 22 24.5 23.62 21.89 of World US Canada 33 835 25.30 * 10 204 20.4 * 43 1039 24.16 Z Czechoslovakia Japan Yugoslavia W Europe N America 2 2 4 8 57 43 30 39 85 154 1248 1039 15.0 19.5 21.2 19.2 21.89 24.16 Rest of World 8 108 154 2441 19.2 22.60 GENC 008614 r tlie countries wltb^>10 cases, France and USA linve average latency period above world average and Germany well below. DISTRIBUTION OF LATENCY PERIODS TABLE 4B (Review Date - 1 Jan 1984) Page 32 0-9 yrs 10-14 yrs 15-19 yrs 20-24 yrs 25-29 yrs 30-34 yrs 35+ yrs Total Average Latency Period BeIgium t 1 | Canada 1 j1 Czechoslovakia t 11 France t 1 i\ 1 11 j1 1 3I t 1 1| <I 1| iJ Germany I taly Japan Norway Sweden UK USA Yugoslavia 11 i1 1t 11 11 it 11 11 11 I 1l1 ii 11 f1 |1 11 4I 1 t I1 t 11 1 1 tf i t1 2I I1 1 11 f TOTAL 11 1l1 i 11 i 11 1 1 1| t1 1 1 1| 1 41 j 9i 1 2I 1 1| Il i 21 11 2t ii 7| i i i i 29 | 1 1 1 1 5I i i i 21 i 6* f 1 2| 1 1| t\ 1f 1 1 1 1 ]J 71 1 4i 1 ! 28 | 1 1 t 1 21 1 t t 5f t 21 1 i 1 1 1 1 1 21 t 31 1 81 1 1 1 1 22 f 1 1 1 1 1 1 1 21 1 1 1 1 1 1 1 i i 1i i 2i \ 41 i \ i i 9i i 11 1i if i f i 18 i1 ii i i 10 i i 20.4 11 i i if 2 1 1 15.0 11 3 if ii 17 It 25.76 It ff 1 1 21 II 18.3 i1 ii II 4 1 i 18.5 1i 1I ii 2 i i 19.5 1 ! 11 if 1 1 i 22 ii it i i 5 I i 24.5 11 i 1 i i 8 I i 23.62 f 1 11 5 11 33 i i 25.30 ii i1 n 4 It 21.2 11 if 11 If 8 if 108 1 i 22.60 if 1 1 * Includes G 03 aerosol can filler (Review date 1 January 1984) TABLE 4C Page 33 LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE MAX POSSIBLE I YEAR OF 1 LATENCY PERIOD | ARITHMETIC MEAN 1 LATENCY PERIOD I FIRST EXPOSURE 1 1 OF LATENCY PERIODS 1 11 11 44 1 1939 1 38* 43 1 1940 1 |1 1 244 - 34.86 1 42 1 1 1 37 ,21,37, 41 ** I7 1 41 1 2 1 32,38 1 1 40 1 3 1 38,14,32 | 1 1 4 1 28,11,24,20,24,34 , 391 718 m 26.59 1 1 5 1 27,22,28,29 | 27 1 1 6 1 21,29,31,26,28,15,23,1 1 1 1 30,35*** 1 1 36 1 7 1 29,24,29,28 1 1 35 1 8 1 28,24,34 I 9 1 30,26,20 |1 1 458 = 24.11 1 1 1950 1 26,22,31,19,23,14,33 1 19 1 1 1 1 19,28,17,28 | 1 31 1 2 1 21**,15 1 1 30 1 3 1 25,22,23,22,20 | 1 1 4 1 21,21,25,25,21,28***,| 1 1 1 22 1 . 592 21.14 1 1 5 1 22,23,24,14,19,21,27*f ' 28 1 1 27*** | 1 1 1 6 1 21,12,27*** I 26 1 7 1 19,17,15,13,16 | 1 1 25 1 8 1 18,18,15,17,20 | 1 1 9 1 16,21 - | 328 SB 16.4 1 1 1960 1 13,18 1 20 1 1 1 1 15,16,16,16,19,18,12 1 1 21 1 2 1 13,18,17,12 | 1 20 1 3 1 16,17 | 1 1 4 1 16,17 I 102 = 14.57 1 1 5 1 11 17 1 1 6 19 1 1' 16 1 7 1 16 | 1 15 1 8 1 11 1 91 1 11 1 1970 1 1 1 VIOLA i 1 11 1 1i 11 1 2 1 1 Ij 10 1 3 1 1 1 MALTONI 1 1 41 1 1 GOODRICH I I TOTAL 1 108 1 2442 s 22.61 1 I 11 1 108 11 * Cholangiosarcoma ** Aerosol can filler *** US33, 34 and 36; and F15 and 16 still alive. PJST80061400,11/WPX7-2 GENC 008616 (Review date 1 January 1984) Page TABLE 4D LATENCY PERIODS OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND GEOGRAPHICAL LOCATION MAX POSSIBLE 1 YEAR OF | LATENCY PERIOD 1 FIRST EXPOSURE | LATENCY PERIODS IN WESTERN EUROPE 1 NORTH AMERICA 1 44 1 1939 1 1 1 1 38* 43 1 42 1 41 1 1940 1 2 1 | 37,41*** 1 1 1 21,37 1 32,38 40 1 3 I 38 1 14,32 1 4 I 28 1 11,24,20,24,34,39 1 5 1 27 1 22,28,29 1 6 | 21,29,31,33 1 26,28,15,23,30,35*** 36 1 7 I 29 1 24,29,28 35 1 8 1 28,34 1 24 1 9 1 30,26 1 20 - 31 30 1 1 1 1 1950 1 2 3 I 26,22,31 1 19,28 I 21** 1 25,22 1 19 1 17,28 1 15 1 23 1 4 | 21,21,25,25 1 21,28*** 1 5 1 '22,23,24 ,27*** 1 14,19,21,27*** 1 6 1 21,12 1 27*** 26 1 7 1 19,17,15,13 1 25 1 8 I 18,18 1 15 1 9 1 16,21 1 1- 1 1960 1 13,18 1 1 1 | 15,16,16,16,19,18 1 12 21 1 2 1 13,18,17 1 12 20 1 3 1 16,17 1 1 4 1 16 1 17 1 5 1 11 1 1 6 19 1 16 1 7 1 16 1 15 1 8 1 1 91 1 1 VIOLA 1970 1 1 1 I 1 21 1 I 1 MALTONI - 3 I 1 1 TOTAL 1 57 1 43 1 ROW I 1 1 1 1 1 1 1 1 1 1 1 1 1 23,14 1 1 1 1 22,20" 1 1 22 1 1 1 1 16 1 1 17,20 | 1 1 1 1 1 1 1 1 1 1 1 1 1 II 18 1 * Cholangiosarcoma ** Aerosol can filler *** US33, 34 and 36; and F15 and 16 still alive P TSTROOfil400.1 ? /UPY7-? 6ENC I (Review date 1 January 1984) TABLE 4E Page ;? PLANT START UP DATE LATENCY PERIODS OF ASL CASES NO OF CASES AVERAGE LATENCY PERIOD 11 1 LOUISVILLE 1 1940? 1 12,14,15,19,19,20,24,27,28,28,28,29,29 1 11 |1 SHAWINIGAN 1 1941? 1 11,12,14,21,22,23,24,24,26,28 1 11 S CHARLESTON 1 1939? 1 24,30,32,32,34,35,37,38,38,39 1 11 TROISDORF 1 1954 1 12,13,16,16,17,18,19,21,23,25 1 11 1 1 13 | 10 | 1 10 | 1 10 | 1 22.46 20.5 33.9 18 PJST80061400,13/WPX7-2 GENC 00841S (Review date 1 January 1984) TABLE 4F Page LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT YEAR OF FIRST | I1 1 EXPOSURE | S CHARLESTON 1 LOUISVILLE 1 SHAWINIGAN 1 TROISDORF 1939 1 38 I 1 1 1940 1 11 1 1 1 37 I i 21 1 2 I 32,38 I 1 1 3 1 32 i 1 14 1 4 1 24,34,39 I 20 1 11,24 1 5 1A I 28,29,27 1 22 1 6 I 30,35 1 1 26,28 1 71 1 29,28 1 24 1 8I 1 24 1 1 91 111 1950 1 1 19 1 1 11 11 1 21 1 15 1 1 31 1 1 23 1 41 1 28 1 1 21,25 51 1 14,19 1 1 23 61 1 1 1 12 71 1 1 1 13 81 11 1 91 11 1 1960 1 11 1 11 1 1 12 1 16,16,19,18, 21 1 -12 1 1 17 PJST80061400,14/WPX7-2 EMC OOSM (Review date 1 January 1984) Page 3? TABLE 4G PLANT SUNDSVALL BRIGNOUD ST FONS ! 1 1 I 1i I i1 I i BARRY I 1 BURGHAUSEN I NIAGARA i | 1 SPLIT 1 I START-UP DATE | LATENCY PERIOD OF ASL CASES 1 11 11 1945 1 16,19,27,29,31 1 1950 1939 1948 1933 1947 1941 1 11,16,18,26,30 1 I 21,28,29,37,38,27,41,34 1 1 9,17,18,28,31,33 1 H 17,21,22,25 1 I 15,17,21,23 1 1 1 20,20,22,23 1 1 1 1 1 1 NO OF 1 .AVERAGE PERIOD CASES 1 1 5 1 24,4 years 1 5 1 20.2 1 8 1 31.88 6 1 22.66 1 4 1 21.25 i 4 1 19 1 1 4 1 21.25 PJST80061400,15/WPX7-2 SENC 008620 (Review date 1 January 1984) Page > TABLE 4H LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT YEAR OF | FIRST EXPOSURE I 1939 1940 1 2 3 4 5 1 1 1 1 1 1 1 61 7 8 9 1950 1 2 3 4 5 6 7 8 9 1960 1 2 3 4 I 1 1 1 1 1 1 1 1 1 1 1 1 1 1 I 1 1 51 61 1 SUNDSVALL I 1 1 1 1 1 27* 31 29 1 1 I 1 1 1 I 19 1 1 1 1 I 1 ! 1 1 1 1 1 1 16 1 1 1 1 BRIGNOUD 1 1 I 1 1 1 1 1 1 1 1 26,30 1 1 1 1 1 1 1 1 1 18 1 16 1 1 1 1 J 1 11 1 1 I1 ST FONS 1 BARRY 1 11 11 37, 41 1 1 11 38 1 1 11 I1 29 1 1 11 28,34 1 1 11 1 31,33 I 1 28 1 11 11 11 27 1 21 1 1 1 11 11 1I 11 11 1 18 1 1 17 1 1I 11 19 1 1 BURGHAUSEN | 1 1 1 1 1 1 1 1 1 1 1 1 1 1 25 | 21 | 22 | 1 17 | 1 1 1 1 1 1 1 1 1 1 NIAGARA 1 1 1 1 1 I | 1 15,23 1 1 1 1 1 17 1 1 1 ! 21 1 1 1 1 1 I 1 1 1 1 1 1 SPLIT 23* 20 22* 20 * Monomer workers JS/JH/DSO 16 25 January 1984 PJST80061400,16/WPX7-2 GEMC TABLE 5 f (Review Date - 1 Jan 1984) Annual Incidence of ASL Cases (Date of Death) by Geographical Area Page 39 1955 7 1961 2 4 7 8 9 1970 1 2 3 4 5 6 7 8 9 1980 1 2 1983 TOTAL 1 11I 1 Western Europe | North America f Rest of World 1 Annual Total t t1i 1 |1 i 11 1 1 1 1 i1 l i1 i1 i1 14 I1 13 I1 il f1 (1 1 (5 t2 i1 f2 11 )4 f2 1 11 i l1 1 11 i 11 2 1 11 I t5 1 13 t 12 i 13 i t5 i 318 11 - ( 5 1 6 i 4 i 1 i 11 16 f3 I 2 t 11 16 13 i 19 |7 12 i i i 10 | 5 1 ,- t - i 5 16 14 fo 14 t0 t1 i1 nil to date i ) 10 4 1 f3 (1 i nil to date | 3 I 55 * | 40** 1 8 f 103 * Includes G03 aerosol can filler but omits It 01 bag extruder 1 Cumulative 1 1 Total 1 Key Events 1 I 11 'I 2 t 1 31 14 1 1 1 1 1 f 16 |7 i 12 1 15 1 17 1 20 1 25 1 33 1 38 I 49 I 60 1 69 1 79 1 84 ( 94 1 98 I 99 (103 1 t 1 1 1 1 f l 1 l t 1 1 1 1 1 1 1 f 1 t 1 1 Viola 1 1 i Maltoni j Goodrich 1 1 1 1 1 1 t 1 1 t ** Does not include US33, 34 and 36; and F 15 and 16. All still alive. GEMC 008622 (Review date 1 January 1984) Page TABLE 6 ASL CASE NUMBERS BY YEAR OF DEATH AND GEOGRAPHICAL LOCATIONS (EXCLUDING ITQ1) 1 KEY 1 I EVENTS 1 1 1 1 1955 16 17 18 19 1 1960 11 I2 13 14 15 16 17 18 19 |Viola 1 1970 11 12 IMaltoni 1 3 |Goodrich 1 4 15 16 17 18 1 19 1 1980 I1 12 13 1 Total 1 WESTERN EUROPE FI G1 Swl G2 N1,Sw2,UKl,It2 G3** G4,G5,UK3 F2,F3,G6,G7,G8,It3 Bl,F4,F5,F6,F7,Sw3 F8,F9,G10,G11,G12,Sw4 F10,F11,G9,G13,G15 G16.G17 F12,F13,UK4,UK5,G18 UK6, UK7,Gl9,Sw5,G20,G21 It4,F14,UK8,G22 UK09, It5, F17 55 **' 1 1 NORTH AMERICA 1 1 REST OF WORLD 11 11 1 Cl 1 1 1 C2 1 1 11 11 11 1 US8 I C3 1 1 11 1 US5 1 Cz2 I1 11 1 1 C4,C5,US4,US7,US10 1 US12,US16 1 1 1 1 US11 1 C6.US2 1 C7 1 1 1 I C8,US1,US3,US23 1 C9.US13 1 US6,US9,US18,US26 1 Y1.Y2 ,Czl 1 1 Japl I US19,US20,US22, I CIO,US21,US24* 1 Jap2, Y3 1 I US27.US28 1 Y4 11 11 | US17, US29, US30, US32 11 1 US31 1 US35 | 40*** 1 1 18 11 * Cholangiosarcoma ** Aerosol can filler *** Does not include US33, 34 and 36; and F15 and 16. All still alive. PJ ST80061400,1/WPX7-2 gbc 008*4: (Review dace 1 January 1984) Page 41 TABLE 7 ASL CASE NUMBERS BY YEAR OF FIRST EXPOSURE AND GEOGRAPHICAL LOCATION (EXCLUDING ITO1) "" I KEY I I EVENTS I 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 11 1 I Viola 1 | i 1 WESTERN EUROPE 1 1 NORTH AMERICA 1 I REST OF WORLD. 11 1 1 1939 1 1 1 US24* 1 1 40 1 1 1Frl1,Frl6*** 2 3 I Frl4 4 IUK1 5 |Sw2 6 |Frl,Fr3,Sw4 7 1 Sw3 8 1Fr9, Frl7 9 |Frl2,Fr4 50 |Fr7,N1,UK8,UK9 1 |Swl,UK5 2 | G3** 3 1G15,It3 4 IG7.G8.UK4.G19 11 1 C3.US27 1 1 US13, US29 1 1 C2.US19 1 1 Cl,C5,US5,US7,US28,US35 1 1 C4.US3.US9 1 1 C7,C9,US8,US11.US21.US31I 1 C6.US22.US26 1 1 US1 1 1 US12 1 1 US16 IY2, Cz2 1 US10, US32 1 1 US4 1 1 CIO IJapl.Yl 1 US18,US33*** IY3 1 1 I | 5 1G11,G16,G18, Frl5*** 6 1 FRIO,G1 7 |Fr8,G4,It2,G2 8 1Fr6,B1 9 |Fr2,It4 60 IG5.G13 1 US2.US17.US20.US34*** 1 US36*** 1 1 US23 1 1 1 1. 1 Czl |Jap2,Y4 1 1 1 1 | | 1 1 1 |G9,G10,G12,G17,G20,G22| C8 2 IG6.UK6.G21 1 US6 3 1Fr13, UK7 1 4 I Sw5 1 US30 5 1 Fr5 1 6 IUK3 1 7 |It5 1 81 1 91 1 70 1 1 1! 11 11 11 11 11 11 11 11 11 II I II | Maltoni | 3I 1 11 1 1 Total|57 1 11 1 1 1 43 1 1 1 18 1 * Cholangiosarcoma ** Aerosol can filler *** US33, 34 and 36; and Fr 15 and 16 are still alive. PJST80061400,2/WPX7-2 6HC ^I\CV1UW litH-t: 1 1ZO-IJ 11^ TABLE 8 WESTERN EUROPE PVC PRODUCERS - START-UP DATES vs ASL CASES (CMITnNG G03) 1 1 1 1 COMPANY NAf 1 IXXXTICN | ASL CASE NUMBER 1 YEAR OF YEAR 1 1 1 1 1 1st Exposure | 1931 IWest Germany IBASF Hudwigshafen 1 1 1 1933 IWest Germany IWacker IBurghausen 104,07,11,15 157.54,55,53 1 1938 I Italy IMontecatlni |Acna 1 1 1 1939 (France I Rhone Poulenc ISt Fons 103.09.10.11,14. 146,48,56,41,43, | 11 1 115.16.17 155,41,48 | 1940 (United Kingdom| Id I Runcorn 1 1 1 1940 1 United Kingdoml ICI I Hi 11house 101.04 144.54 | 1945 I Sweden IKemanord I Sundsvall(Stockvik) |01,02,03,04,05 151,45.47.46.64 | (Switzerland |Lanza (Sins 1 1 1 1946 I France IRhone-ftxilenc IRousillon 101 146 | 1947 IItaly IMontedison I Porto Marghera 102 157 I 1948 1United KingdomIBP them I Barry 103,05,06,07,08,09166,51,62,63.50,50 I (West Germany IHjIs (Marl 109,10 161,61 l 1949 I Belgium ISolvic IJsneppe 101 158 | 1950 IFrance IFuk IBrlgnoud 102,04,05,06,12 159,49.65,58.49 1 I France IRhone-Boulenc |St Auban 107 150 I I Holland 1 Shell IPemis 11 (Norway INorsk IHeroya 101 150 I 1951 (Italy IMontedison 1 Brindisi 1 1 1 1952 1 Italy IMontedison ITferni 1 1 1 1953 1 Austria I France IHalvic ISolvic IHallein ITavaux 1 108,13 1 157,63 1 | 1Italy ISolvic I Ferrara 103 153 I |Spain |Rio Rodano IHernani 1 1 1 IUnited Kingdom]BIP lAycllffe 1 1 1 IWest Germany IHoechst IGendorf 118 155 | 1954 IWest Gernary IDynamic lTroisdorf 101,02,08,12,16, 156,57,54,61,55,61,1 11 1 117,19,20,21,22 154,61,62,61 I 1955 1 Spain IMonsanto Iberia IMonzon 1 1 1 1956 |Spain ICaiqsa ISabinanlgo 1 1 1 1 IHlspavic ITorrelavega 1 1 1 1958 IWest Germany ISolvay IRheinberg 1 1 1 1960 |Italy IS C Ravenna 1 Ravenna 104 159 | 1960 IWest Germany ILonza IWaldshut 106,13 162,60 | 1962 I Portugal ICires IOporto 1 1 1 1965 | France IRhone-Poulenc IMontlucon 1 1 1 |Italy Iftozzi IFerrandina 1 1 1 IWest Germany IWacker ICblogiK 1 1 1 1966 IWest German'/ IHoechst 1Knapsack(Frankfurt^ 105* 160 1 1967 |France IAIO Chimie IBalan 1 1 1 |Spain 1Greece |Rio Rodano |Esso Pappas 1Miranda de Ebro 1 IDlavata Salonika 1 1 1 1 1 1968 IBel^iun IBadiphil IAntwerp 1 1 1 1969 I United Kingdom IVinatex IStaveley 1 1 ! |Italy iRumianca irajrHflri Sardina 1 1 1 1970 | Italy ism 1 Porto Torres Sar l 1 1 lliiited Kingdom)ICI 1 Runcorn 1 1 1 1971 I Italy IS C Ravenna 1Ravenna 1 1 1 ISpain IHlspavic IMartorell 1 1 1 |Sweden IKemanord 1Stenungsund 1 1 1 |Uhited Kingdoml BP (hem IBaglan Bay 1 1 1 1972 |Finland IPekana ISvartback 1 1 1 |Holland IDEM IBeek Llriurg 1 1976 | France ISoc Art D'viny! IMazingarbe 1 | GEHC 0086 c- 1977 (Spain (Monsanto Iberia 1 Tarragona 1 * Laboratory worker in Research Department **Pansac,Mtra Venice, case not included. (It 05) due not knowing start up date of the Plant. PJST80061400,3/WPX7-2 (Review date 1 January 1984) Page TABLE 9 USA PVC PRODUCERS - START-UP DATES vsASL CASES START-UF | COMPANY NAME YEAR 1939? l*UCC 1940? |*BFG 1946? 1947 1948 |*UCC I Goodyear 1 Firestone I Uniroyal ^ 1950 1952 1953 1954 1956 1957 1958 1960 1 Monsanto 1 Dow I BFG 1 Diamond I General Tire I Air Products I Atlantic Refining I Borden 1 Conoco 1 BFG 1 Great American I Plastics 1 Hooker | Pantasote | Atlantic Tubing I Tenneco I Keysor Century | BFG I Air Products 1962 1963 1965 1966 1967 | Borden | Tenneco 1 Conoco I Stauffer 1 Conoco | Ethyl | Diamond |General Tire/Pantas 1 BFG I Stauffer | Allied 1968 1969 1971 | Hooker | Firestone | BFG | Goodyear | Olin | (Formerly Conoco) | Conoco LOCATION S Charleston Louisville Texas City Niagara Falls Pottstown Painesville (closed 1975) Springfield Midland Avon Lake Deer Park Ashtabula Pensacola Brooklyn Leominster Hebronville Niagara | ASL CASE 1 YEAR OF | NUMBER 1 1st EXPOSURE 107,13,19,21,24 ,144,42,43,46,39, 127,28,29,31,35 141,44,42,46,44 101,02,03,04,05 ,148,55,45,52,44, 106,09,16,17,22 ,162,45,50,55,47, 126.33.34 147,54,55 r ! 1 108,10,11,20 112 1 1 146,51,46.55 749 ------------- 1 ! 11 132 151 11 1 18 154 11 136 156 11 11 11 11 11 Fitchburg 123 158 1 Hicksville 1 Passaic 1 Cranston 1 Flemington NJ 130 Saugus, Cal 1 Watson, Cal 1 Calvert City 1 (closed March 1982) Illiopolis 1 Burlington NJ 1 Aberdeen, Miss 1 Long Beach, Cal Assonet, Mass 1 Baton Rouge 1 Delaware City 1 Mt Pleasant W Va 1 Henry, 111 1 Delaware City 1 Painesville, 0 1 (sold to Robintech) Burlington NJ 1 Perryville i Fedrickton NJ 1 Plaquemine 1 Assonet, Mass 1 1 1 1 159 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 Oklahoma Clty 1 I 1 GBC 003*2* PJST80061400.4/WPX7-2 TABLE 9 (Continued) Page 44 USA PVC PRODUCERS - START-UP DATES vs ASL CASES I START-UP 1 | YEAR 1 1972 i 1 1973 I | COMPANY NAME Nat Starch Borden Robintech 1 1974 | Atlantic Tubing | Shintech 1 1975 1 Certain-teed 1 Georgia Pacific I Tenneco 1 1979 1 Firestone | LOCATION 1 | Meredosia, 111 I Springfield | Painesville, 0 | (sold to Georgia | Pacific who | converted to | polystyrene) | Cranston RI | Freeport, Tex I Lake Charles I Plaquemine, La | Pasadena, Tex | Plaquemine | | ASL CASE NUMBER ! YEAR OF | 1 1st EXPOSURE I 1 1 1 1 I 1 1 I 1 1 1 1 1 * My databank has no information on UCC before 1946 or BFG before 1950 NB Some of the plants in this list were closed down, some have changed ownership over the years PJST80061400,5/WPX7-2 OENC 008627 I (Review date 1 January 1984) TABLE 10 Page 4;; CANADIAN PVC PRODUCERS - START-UP DATES vs ASL CASES START-UP YEAR 1943 (1941?) 1951 1957 1966 1979 COMPANY NAME Goodrich Monsanto* Goodrich Esso Diamond Shamrock Alb 1 LOCATION 1 1 1 Shawinigan 1 1 1 1 La Salle 1 1 1 Welland I 1 1 Sarnia 1 1 1 Fort Saskatchewan 1 I ASL CASE 1 YEAR OF I NUMBER 1 1st EXPOSURE 11 101,02,03,04,05 144,43,41,45,44, 106,07,08,09,10 147 ,46 ,61 ,46,53 11 11 1 11 11 11 11 11 11 11 11 11 11 l i ! t 1 I 1 1 1 ) 1 1 1 1 l 1 1 1 * Terminated 1975 PJST80061400.6/WPX7-2 GENC 008628 (Review date 1 January 1984) Page 45 TABLE H EASTERN BLOC PVC FACTORIES - START-UP DATES vs ASL CASES START-UP| COUNTRY NAME | COMPANY NAME YEAR i 1 Pre 1939|East Germany I State Company 1941 (Russia I State Comps 1950 |Yugoslavia (Jugo Vinil 1951 I Czechoslovakia!State Comps 1955 |East Germany 1 State Comps 1956 |Rumania I State Comps 1957 1 Poland 1 State Comps |Rumania |State Comps 1 1958 |Rumania 1 State Comps 1959 1 Hungary 1 State Comps 1961 I Rumania I State Comps 1963 I Yugoslavia lOhis 1965 I Bulgaria 1967 |Poland 1 State Comps I State Comps 1969 1 Russia I State Comps 1970 I Rumania I State Comps 1 Russia I State Comps 1972 1 Yugoslavia |Vinilplastika 1975 I Czechoslovakia (State Comps I Russia I State Comps 1976 1 Yugoslavia 1977 1 Rumania 1 Hip 1 State Comps 1 LOCATION 1 1Schopau I Vladimir et al (Split INovaky IBitterfeldt 1Icechim lOsweicim (Dwory) |Tirnaveni |Turda IRisnov IBerente Borsod IBorzesti 1 Skopje |Varna ITarnow I Djerjinsk IRimnicu Vilcea |Volgograd |Zadar |Neratovice IKalush Area |Pancevo IRimnicu Vilcea 1 ASL CASE 1 NUMBER 1 1 101,02,03,04 101,02 1 1 1 1 1 1 1 1 1 1 1 1 1 I 1 1 1 1 1 YEAR OF 1 1st Exposure 1 1 153,50,54,48 157,50 1 1 1 1 1 1 i i i i i i i i i i i i i PJST80061400.7/WPX7-2 Li (Review dace 1 January 1984) Page TABLE 12 JAPANESE PVC PRODUCERS - START-UP DATES vs ASL CASES START-UP 1 COMPANY NAME YEAR 1950 I Chisso Corp | Kanegafuchi Kag I Tekkosha 1951 1 Mitsui Toatsu 1952 1 Mitsubishi Mon I Sumitomo Kag 1951 I Denki Kagaku 1 Nippon Zeon | Toa Gosei 1955 | Ryo-Nichi 1956 I Nippon Zeon | Nisshin Kagaku 1957 | Kureha Kasei I Shinetsu Kag 1960 I Denki Kagaku | Kanegafuchi Kag 1964 | Chisso Corp 1966 I Tokuyama Seksui 1967 1 San Arrow Kagak I Sumitomo Kag 1968 I Ryo-Nichi 1 Shinetsu Kag 1970 1 Chisso Corp I Denki Kagaku I Kanegafuchi Kag I Kawasaki Yuki I Mitsui Toatsu I Nissan Kagaku 1 Shinetsu Kag 1971 1 Tekkosha 1973 j Asahi Glass 1974 1 Toyo Soda 1975 1977 I Central Kagaku 1 Toyo Soda I Unknown I LOCATION 1 | Minamata I Osaka I Sakata I Nagoya | Yokkaichi | Kikumoto | Shibukawa I Kambara | Tckushima I Uozu I Takoaka I Takeo 1 Nishiki I Naoetsu 1 Ohmi I Takasago 1 Chiba | Tokuyama I Tokuyama I Chiba I Mizushima I Tokuyama | Mizushima I Goi (Chiba) I Kashima 1 Kawasaki I Sakai | Chiba | Kashima I Yokkaichi I Hayatsuki I Sakata 1 Yokkaishi 1 Kawasaki I Yokkaichi | Kashima i ASL CASE | NUMBER I 1 I 01, 02 I 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 YEAR OF 1 1st EXPOSURE 1 1 1 1 53, 58 1 1 1 1 1 1 1 1 I 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1. 1 1 1 1 1 PJST80061400,8/WPX7-2 StHC OVlS*3'3 (Review date 1 January 198A) Page 45 TABLE 13 SOUTH AND CENTRAL AMERICAN PVC PRODUCERS |START-UP 1 | YEAR 1 1 1953 1 1 1954 1 1 1955 1 1 1956 1 I 1960 1 1 1 1961 1 I 1965 1 I 1 1966 1 1 1967 1 1 1968 1 1 1970 1 1 1 1971 1 1 1975 1 1 1976 1 1 1977 1 I 1978 1 1 1 1 1979 1 COMPANY NAME Monsanto Mexica Policyd Geon Do Brazil Elchlor Electrochlor Viplastic Indupa SOC Paramanga PET Columbiana Carburo De Col Plasticos Omega Primex Policasa Petro Dow Polimeros Mex Rico Chemicals Petroplas Xndust Resistoc Huls Brasil Polychem Policyd PET Camacari | LOCATION | 1 | 1 Lecheria (Mexico) | Mexico City (Mexico) I Sao Paulo (Brazil) | Sao Gaetano lBrazil) 1 I I 1 ICapitan Bermudez(Argentina)I | Mendoz (Argentina) | I Cinco Saltos (Argentina) | | Pararaonga (Peru) | Cartagena (Colombia) | Medellin (Colombia) 1 1 1 I Mexico | Puebla (Mexico) I Managua (Nicaragua) 1 1 I I Conception (Chile) 1 I St Martin Puebla (Mexico) | 1 Guyanilla (Puerto Rico) | EL Tablazo (Venezuela) | | I Tlazcala (Mexico) I Cubato ^Brazil) 1 1 I El Salvador | Coatzacoalcos (Mexico) I Camacari Bahia (Brazil) 1 I 1 ASL CASE NUMBER 1 YEAR OF I 1st EXPOSURE 1 1 | 1 1 I 1 1 1 1 1 1 I I 1 1 ! i i i i i '61400,9/WPX7-2 6ENC 008631