Document G5J70bqY0v0kg79eYd35Yz27V
TABLE I
TEST . MATERIAL: Vin'yl Chloride (Ethylene Derived)
Chronic Vapor Inhalation Toxicity Study - Albino Rats, Albino Mice, and Golden Hamsters
I
!.
Chamber Concentration Data
Day * Exposure Number Number
1 4 5 16 29 39 66 73 80 99 120 130 150 151 152 171 186 107 197 , 200 201 208 212
220 221 229 232 235
1 4 5 12 21 29 48 53 5B 71 86 94 108 109 110 123 134 135 141 144 145 150 152 158 159 165 166 169
TE-I Ranee
Mean
39 45 50 42 48 42 48 42 45 29 45 42 35 32 41.5 35 47 46.5 40 38.5 37.5 48 36 36.5 44.5 46.5 47 44
45 43 .
54 51
56 52
63 60
66 58
55 43
114 84
58 49
60 54
31 - 30
46 45
63 53
58 49
62 44
110 58.9
55 48
53 49.6
55.5 1 '50.7
55 45.1
56 ' `49
55.5
48
54.5
51.4
64.5
48.1
52. 5
45
55 '
49.2
46 49.4
71 52.3
51 47.6
Chamber Concentration (ppm)
TE-II
TE-III
Ranae
Mean
Ranqe
Mean
130 24
182 54
192 188 172 178 220 258 168
180 90
150 170 186 184 180 178 178 174 170 154 138 130 190 184 196
180 162 237 266 248 216 4 52 211
364 310 232 228 288 234 252 210 224 262 216 310 212 242 282 250 138 216 228 215
173 87
218 156 219 209 298
202 243 277 199 201 200 193 198 197 209 194 196 223 197 200 194 192
134 200 201 207
1820 2610 1190 3600 1160 3100 2400 3100
1090 2490 1900 3010* 2240 4000
2380 2700 2020. .2760 2740 3940 1960 2960
2680 3100 1780 2920 1280 2800 2300 2 BOO 2320 3020 2040 2680 2100 3400 2400 2700 2340 3120 2340 2740 2260 3420 2160 3200 1440 2600 2460 2620 2420 2800 2100 2820 2440 3710
2510 2540 2202 2653 1561 2455 2910
2565 2404 3185 2565 2883 2556 2349 2497 2708 2419 2550 2535 2561 2500 2627 2583 2240 2540 2583 2520 2932
'
TE-IV**
Ranqe
Mean
SBZ900 S9U
90Z9OO SSU
TABLE I continued
TEST MATERIAL: Vinyl Chloride (Ethylene Derived)
Chronic Vapor Inhalation Toxicity Study - Albino Rats, Albino Mice and Golden Hamsters
Chamber Concentration Data
Day Exposure Number Number.
TE-I Range
240 274 2 75 281 304 312 315 316 318 32 3 332 333 3 39 345 351 359 360
178 196 197 201 210 224 225 226 228 231 230 .239 243 247 251 257 248
-
47.5 44.5 38 40 45.5 39 37 46 46.5 49.4 56 47.5 40 49.5 35 46 44.5
52.5 51 56 56 50.5 46 52.5 55 52.0 62 56 55 60 51 45.5 71 59.5
Mean
51.2 4 7.9 49.5 47.5 48.2 42.8 44.2 54 49.2 54.9 56 51.3 48.9 50 39.5 56 50.7
Chamber Concentration (ppm)
TE-II
TE-III
Range
Mean________ Range_________ Mean
186 188 174 168 202 148 146 182 170 176 206 185 184 190 180 202 170
222 216 242 232 226 172 196 220 280 250 208 210 234 210 246 208 216
203 202 198 204 218 160 174 208 192 208 208 202 203 203 228 206 202
2420 2180 2160 2360 2140 1800 1800 2080 1960 2160 2260 2160 2380 2140 2640 2420 2360
2700 2580 2640 2740 2460 2040 2440 2500 2380 2840 2380 2600 ' 2960 2620 2900 2560 2840
2573 2377 2386 2515 2288 1920 2073 2473 2022 2475 2300 2556 2607 2525 2783 2407 2602
T-IV* *
Range
Mean
* Previously reported by IBT as 1970- 2770, with a mean of 2474 A A Only gross inspections were made of the TE-IV concentrations but the same problems existed
with this concentration as with the others.
R&S 006737
TABLE II IBT No. 663-03222 VINYL CHLORIDE RATS - SURVIVAL
T--III - 2,000 ppm
Month
5 Report Printout
6 Report Printout
7 Report Printout*
8 Report Printout
9 Report Printout
10 . Report Printout
11 Report Printout
12 Report Printout
13 Report Printout**
Male
97 96
95 96
94 89 or 92
90 89
84 82
76 74
66 62
42 37
27 23
Female
96 95
96 94
95 92
92 90
85 81
72 68
48 46
34 15 (?)
17 5 (?)
* None of #'s or weights agree with report ** A1H over the.lot, 5 body weights shown