Document Ex8qNby8a6MZ6awv4Geqdk51j

--"-raifniftiiiiiiiu, -- ......... Hyin Dtg Amust, 1962 'available*. In a number of common processes, a variety of basardous fumes nod gages ora produced, in certain of the**, lower maximum allowable concentration# for the major com* ponenta than those uaad for lb* pure eubaiance are propoaad. -* Author*i nbst. .I tuns--Findlnt Texlcltr Paut Mat VI* H. P. Smyth, Jr* at ml. y^. iAST'Hyg. Asia.}. 21. 9S-I07(Mar.-Apr, 1962), A table preaanla acute toxicity and irritation data on mora than SCO compounds* ac cumulated In a continuing program for acraaning potential commarefill product*. The standard ised experimental methods are described* Authors' abat* wan TAe gets.raalnatlnn.Af AJxinary JFluoaldea* i. guoi* J* 1-- Monkmsn and T. Tsicbmaa, Am. ind. Hyg. Ann. J. 23, <5T-io| (Mar*-Apr. 19622* - Determinations of fluorldaln urlqp by in ion exchange procedure and by tjfeleqteo- . nitric method are .discussed/ Reaphe gr# compared for replicate sample safcfjyssd by these *. * ,/ methods and by tbe# distillation prbceduVh^ The Sccuraay.pf the tfcreV'methodi vai found to>e o/ tber same order/ The reproducfbiflty Wthe electrometric method ,wai superior*and the method waimorh rapldC ` Aubore*'a6et* . Experimental Research into Tellurium as an Industrial Poison* S. E. Sandratekaya* GlgienaTruda i Prof. Zabolevantya 6, 44 (Feb. 19o2). The author describes inveitigattons into the toxic properties of the aerosols resulting from condensation and disintegration of elemental tellurium and its dioxide, and into the chronic respiratory poisonings resulting from exposure to these aerosols. .These investigatione re vealed that the finely dispersed oxidised condensation aerosol is the mast toxic* Is concentra tions of 0*05 mg. per liter it reduces the growth rate of animals* reduces erytbrocyt# count* the hsmoglobln level, and the eataUse, and changes the norms! rstio of the serum protein frac* linos. Tbs livar is the organ that is most susceptihls to the injurious offset* of this toxic aero sol* Its synthesising function is impsirsd, and autopsy studies reveal fatty degeneration* The nervous system Is also damaged (prolonged ehronaxy with predominance of inhibitory proceaaea and paresis of tbs hind extremities and tail). In a concentration of only 0.01 mg, per liter the w * toxicity of this asrosol was slight! it producsd only transitory and revarsible changes* Aero sols resulting from diiintegrstion produce analogous ehangss only in concentrations 10 times a* high (0.1 mg. per liter). These det* make it possible to eitsblfsh differential rating* for the maximum permissible l.evel* of tellurium SerosoU in the atmosphere Of Industrial premises* -- J. Am* Med. Assn. JUferenees and lUvlewe :/ ;! Til Chlorate Poisoning. N. C, KUndahoJ, et 0). J. Am. Med* Assn. J80, 1111-1114 (June 10. 1962). The patient was a 29-year-old Korean physUian engaged in the study of renal phy siology. By mistake he ingested 40 g. of sodium chlorate. The major feature of the treatment was the combined use of Mood dialysis and exchange transfusion using a total of 19 pints of donor blood. Ml lavestlaaiior.s of the Toxicity of Sodium Aside, t, Experimental lnveatUatlona of Acute and Subacute Toxic Activity. E*s Bassendovyika and 2. Kowalski. Mt*d,Pr*cy iLodai J_2. 427-442 (l?6l|. Polish. * The toxicity of.sodium, aside lNN,) wee stymied in rat# and mien given the compound ubcuff'naoasly in doles of 11*72 mg. psr kg* The LDgo was 49.1 mg: per kg, for rste sod . . 2l.4)i mg. per'kg. *for mice. The animals died with paralysis end respirslory failure. The 1*0*3 for rats on intratrscheal injection of shout 9.4 cc. of an aqueous solution was 47,5 mg*, per kg, 'Irregular.results were obtained when*sodium aaide was applied to the skin and conjunc thr*of rabbits* but the compound w*e evidentlyabsorbed by botb'tbese routes. Subcutaneous 11.