Document Evddv795Y5jvoOno9ebyYDgpL
FILE NAME: Johnson & Johnson (JAJ)
DATE: 1972 Oct 27
DOC#: JAJ058 DOCUMENT DESCRIPTION: Report - Examination of J&J Baby Powder with Handwritten Note: "Do Not Use This Report. Replaced by Another Version."
Dr. . J . Goudle Johnson and Johnson
Research Center SOI George Street New Brunswick, New Jersey 08901
EXAMINATION OF
JOHNSON AND JOHNSON'S BABY POWDER
Date: 2? October 1972
MA Number:
2546
Copy / of
'4
D drr UvSr
fernte It
'M vM
waiter c. mccron assodatea ine.
2S20 SOUTH MICHIGAN AVENUE CHICAGO, ILLIN O IS 60616
Protected Doeum enHuhfeet to Protective Order
JNJMXM_eONMMD
examination o r Johnson and JOHNn-s baby towdeh
Summary
TWO,,ample* oi JotoBoa and W d W * * >**" ** "Umto
108T and 109T, wMol.eorroBpondt the > # * * Proi" r o
z Lewn, at New York University on M u lt
^
d , * tM mioroacopyi M U M *
" *e1" "
tron diffraction to determine whether they contain anpj|pbestiform minerals.
Both samples contained an insignificant amount oftremolitefeOJ?},
Neither sample contained chrysotile.
Introduction
On
of the FDA, Professor Seymour ? . Lewin of New York
University is examining a number of commercial talcunM||gyders for the presence of asbestiform minerals. Two of the samples which he:||^ jp a m in e d are samples
of Johnson and Johnson's Baby Powder, batch number
batch number 109T
Johnson and Johnson therefore requested Ule&ar C. McCroi|M^soCiafes to 9X~ amine samples from the same batches to determine whether by contained any asbestiform minerals.
Materials and Method of Conducting Tests
Two samples were submitted, identified as Johnson and Johnson's Baby Powder, batch numbers 108T and 109T.
For x-ray diffraction examination, the samples were examined on a Philltps-Norelco vertlcle diffractometer using CuKct radiation and a scanning speed of 1 per minute. The dispersion staining technique was used for the light microscopical examination and the electron microscopy-electron diffraction ex amination was carried out using procedures previously described (MA report 2330-1; dated 10 August.1971).
Protected Document-Subject to Protective Order
w aiter c mecrone associates inc.
JNJMX6S
Results
X-ray Diffraction
The diffractograms were carefully examined in the vicinity of the major peaks of chrysotile and tremolite. Neither mineral was present. The presence of peaks hi the viciniiy of 12.0-12-5 28 , the region in which one of the principal lines of chrysotile may be found, was correlated with peaks in 1he vi cinity of 6 20 and are thus attributable to chlorites. No significant peaks were observed in the 24 region which would be required were chrysotile present.
Light Microscopy
Using the dispersion staining technique and a liquid of refractive index 1.550, the samples were examined for chrysotile particles and fibers, but none could be found. Using a similar technique with a liquid of refractive index 1.605, the samples were similarly examined for the presence of tremolite and a few individual crystals were found, some rod shaped. The total tremolite content of the two samples would be approximately 0.5% for 108T and about 0.2-0.3% tor 109T.
Eleotron Microscopy and Electron Diffraction
Several electron microscope grids from both samples were ex amined in their entirely and although some fibers were observed these were shown by electron diffraction to be shards of talc or rolled talc. No chrysotile fibers were found.
Conclusion
A detailed examination of two samples of Johnson and Johnson's Baby Powder, batch numbers 108T and 109T has shown this material to be sub stantially free of asbestiform minerals. A few tremolite rods were observed in both samples at a level less than 0.5%. No chrysotile has been detected.
Respectfully submitted, /* & * -" *
Ian M. Stewart Manager, Electron Optics Group J -2- w aiter c, mccrone associates, inc.
Protected Document-Subject to Protective Order
JNJMXea_000008J2