Document EqwvOn8eX8LaMgeJEbMVjX6xn

SSo . e 3M Gammon aScmaiineestato P2030 September 5, 2001 8E-H09R 01 -- 0273 . #R226 _ 10385 ii 000943245R Document Processing Center (7407) 400 Suet SW Office ofToxic Substances U.S. Environmental Protection Agency `Washington, DC 20460 Attn: TSCA Section 8(e) Coordinator MWR5p= foo Dear Section 8(e) Docket Coordinator: Re: TSCA 8(e) Supplemental Notice on Sulfonate-based Fluorochemicals `With this letter, 3M is providing final reports and other supplemental information related to previous TSCA Section 8(e) notifications. Manyofthe enclosed items are analytical reports providing blood serum and liver levelsoftest materials for which the in-life report referring to administered doses has already been submitted to the 8(e) docket. In other cases `where the 8(e) notification consisted of preliminary data, we are submitting a final study report. All ofthe enclosed items are already in EPA's possession and available in TSCA Docket AR-226. We believe, however, that placing these items in the 8(e) docket may allow for more convenient access to information directly related to previous 8(e) notifications by 3M. The table below lists the enclosed items and references the study or data which already has been the subject ofan 8(e) notification by 3M: ached Submision Related Study/Data Already Attached Submissio Filed Under 8(e) 1. Amended Analytical Study, 20N-Ethylperluoroocane | Combined Ora (Gavage) Fertil, DesMtuSelSrfm6oi,nnaPamtiRidOooS)n-AoeAtf,hatanhonldPiPrnsFTsOwnScoAeGiaennntdehrCeatoLiionvnecrReaatnndRtePprFroaOofSdtu,PciFtOoiSon,n,|||RDEeeGpvFreOolSdoEuptmieinnoRtnaatlTso,axn3idcMiPteRyreiSfnteaurtdeaylno/cPefosNtNon-.atTa-l M556, PFOSAA, PFOSA and EtFOSE-OH in the Sera of | 6316.5, June 30, 1999, full report Crl:CDBR VAF/Plus Rats Exposed to E{FOSE-OH, 3M | submitted February 15,2000t0 3 = Reference No. T-6316.5, Analytical Report TOX-013, LRN-U2095, June 11,2001. supplement earlier filing = BS| SEoRlx IS E38 5 Ontain NO CBI 5  - "TSCA Page2 Section 8(e) Docket Coordinator 2. Analytical Laboratory Report, Determinationofthe Combined Oral (Gavage) Fertility, Presenceand Concentrationof Potassium Perfluorooctanesulfonate (CAS Number: 2759-39-3) in the | Developmental and Perinatal/Postnatal Reproduction Toxicity StudyofPFOS. SPeFrOuSmvainadGLaivvaegreo,fLSabporraagtuoer-yDRaewploerytNoRa.tUs2E0x0p6o,sed to | in Rats, Argus Inc. Sponsor's Research Laboratories, Study No. 6295.9, June Requestor Project No. 3M TOX 6295.9, October 27, 1999. | 10, 1999, full report submitted February 15, 2000 supplementing 6295.9, April 13,2000. Ref. No. U2636, TOX-028, February 23, 2001 dated June 30, 2000, Section 8(e) filing. July 24, 2000 Concentrationof PFOS, PFOSA, PFOSAA, and EtFOSE- | Developmental Toxicity Studyof2N- OH in the Sera and Liverof Crl:CDBR VAF/Plus Rats Ethylperfluorooctanesulfonamido)- 6. Analytical Laboratory Report on the Determinationofthe | Final Report, Oral (Stomach Tube) EtFOSE) in Liver and Serum Specimens, 3M Environmental Laboratory Report No. TOX-097, Laboratory Request No. U2452, 3M Ref. No. T-6316.8, to Section 8(e) docket per letter of August 21, 2000 Employedatthe 3M Decatur Facility, University of 8(e) docket in letter ofDecember 15,  7" Co. PTaSgCeA3 Section 8(c) Docket Coordinator bmi Attached Sesmision RelateFdilSetduUdyn/dDearta8(Ae)lready 8. FininAallbRienpoorRta,tsA,cSuatfeetOyraElvaTlouxaitciiotnyLSacbroereantowriyt,hRTi-k3e2r90CoC | 3Ac2u9t0eCOorCalinToAxlibciintoyRSactrse,eSnafweittyh T- Laboratories, Inc, No. T-3290 (40 % KPr'ojPeFctOSNoA.A0i8n832A%R0E3I6O2H,, 3M Reference| 17% IPA | LEavbaolruaattoiroinesL,abIonrca,toPrroyj,eRcitkNeor. a1n9d824[0B%iblHi0o,grLa-p6h7y7e8n,trFy-6in8D7o3,ckLeott ASR01-)2,26N,ovfienmablerrep5o,rt || 30289802A(R4003%63K,'3PMFORSefAeAreinnc3e N%o.EtTO-H, | was to be movetdo TSCA 8(e) docket] 17% IPA and 40 % H,0, L-6778, F- 6su8b7m3i,tLtoetd 5to01S)e,cNtioovne8m(bee)rdo5c,k1e9t8i2n, A(wuhgiucsht e2r1r,o2n0eo0u0slseylrfe-faeurdsittolertatebrbits rather than rats) 9. GPieersfyl,uoJro.oPctaanndcsKu.lfKoannantaena,ndAcRceulmautledatFilounoroofchemicals in | P8(rce)lidmoicnkaerty data May 2s6u,bm1i9t9t9ed to Section Fish Tissue, Michigan State University, June 20, 2001. 10. GPeirefslyu,oIrPo.octaanndesKu.lfKoannanteana,ndAcRceulmautleadtFilounoroofchemicals in 2M0i0n1k. and River Otters, Michigan State University, June 20, 11. GRieelsayt,edJFPluoarnodchKe.miKcaanlnsani,n OPyesrtfelr,uoCrroasoscotsatnreeasuVlifrgoinanaintcade, SFtraotem UtnhievGerusliftoyf, JMuenxei2c0o,a2n0d01Chesapeake Bay, Michigan 12. GRieelsayt,edJ.FPl.uaonrdocKh.enKiacnanlasni,nPFeirsfhl-uEoartoioncgtaWnaetseurlfBoinradtse,and Michigan State University, June 20, 2001 13. GPieersfyl,uoJr.oPo.catanndesK.ulfKoannantaen,anAdccReulmautleadtiFolnuoorfochemicals in 2M0a0r1ine Mammals, Michigan State University, June 20, Ifyou have any questions about this submission, please contact me at (651)737-4795. Sincerely, NY Milne Georioh Adams Manager, 3M Corporate Product Responsibility Enclosures