Document EqKyxZ1ZMDywzevBenbZRG2wR

A :v Reference - No. :7 1'. 2. 3. A. 5. 6. 7. 8. 9. , SYMPOSIUM ON ' ENVIRONMENTAL LEAD CONTAMINATION; DECEMBER 13-15, 1965 . : -.PUBLICATION NO. U 0 i:: ' Leo J t Gehrig. ;M.!).> Deputy Surgeon General p. 2, ''size,ble pase of scientific knowledge of its physiologic and toxic effects" - Roy 0. McCaldin. Ph.D ., PHS ' .'' ': 9'';, p. 10, "principal source of atmospheric lead is from combustion of leaded gasoline" //' ' p. 1A, Chart on lead consumption 1926 to 1963. no increase. . , . O' Keith H. Levis. PHS p. 13, "Diet is 90 of intake" Herbert I'. Stokinger. PHS . p. 31, "Urinary lead levels" used as basis for determining lead exposure" Dr. Robert A. Kehoe1s address to panel ?. 51-58 Dr. Robert A. Kehoe p. 55, "80 meg. Is not level above which one. may conclude that person is suffering from lead poison ing but below which there is definitely no lead poisoning" Dr. Robert A. Kehoe p. 57, gives fatal dose of lead for humans. Lloyd B. Tapper. M.D. Bottom p. 60, "absorption of inorganic lead by direct contact is nil". -- "Oral ingestion of materiel which has been applied to skin". -- -middle of p. 61, "lead oleete seems to be absorbable through the skin of rets, but the evidence for absorption by humans Is negligible". HE 0 0 3 y N 14940 10. ' =-i}?: i>*V.- * t/ ' <-V- y.y'y m m m!/iim' .Vbyt'y.y: r- ','i: : tsyis.,, ";-r .!;;;i3, j / V ' -.v , * T7`f. - t - . / -. .. .' ..- ;. . ' -U'.tTf#iJl< iiV- -' 'f:.'"V1i ', '.- .-. , . f : , ). > 1 14. 15, 6, ' .4n-t'v>i ' n*--. - ':Kv.5rv'`. .'j;s,.,V'/t.,j .- ' ; : ,' ,. : '. !ry , 16, v,jl ' \ <*' t V; - .'. |v ,-JT*:;..' "<f! . ( f* J r?! r 2'' -' ', -' ; r- " ' : 17. 18 $ '* 1 f : * ' : 19 t ..... : : .20 "A s>% ' ;;4v:. # :: :j;, j t' ' ':V. -'-:fr'*. 'v#A>, a:*r-.<i: --V*M-i'- ' ." S% ;Vm*v '''.vj .... -:-b.y; 'Ralph G/"Smith. P h i D . V s y n e State University' *' . . -.' ,/ ',`v :Top of pi 66,- ,,lead.'i',.;iabout" which yaore is,perhaps., - knovn today than virtually1'!any other toxic substance" ' . * .> ' i and p, 67> blood.vs, urine. ; ) Ralph G; Smith. Ph.D,, Vayne State,. University. f;!..:v/; '\\l 7 `.V: T; -h' Vy;. VO f . ' ' p, 63,. "Our knowledge of normal values of lead in , man is virtually unequalled for any other substance". , ,J V"Se.fe levels----- adequate". Sii 4':t <; j ])'.< , ' ;:h.:/-^V'' 'fy!' ' Harriet E. Hardy, M.D, . /t 'Bottom of p. 77, ^Growing tissue is nore vulnerable . to lead than dult.jV 'This paper abounds with-biologi- cel effects of .'lead'4.'`f:v-fm. -i y Vy/ty-H .yi-i..;;- 'iy vt:v. /w..:i; :yv,yy/,,y ;v:.u i 5'; .-Harriet E. Herdy...H.D, ,, ! * " '. . .< '. p. 79, "cigarette smokers have slightly elevated blood levels" "also beer drinkers". . ,. . Harriet L. Hards'-. M.D. . 1 : ! . . p. 31, quotes Dr. Hill of Royal Society, (Pres.), "Ve ' need very strong evidence before ve made people stop smoking cigarettes and eating.fats and sugar,,..." , !- Melvin V, First. Harvard University ,; ' p. 89, amount of lead lost to environment. . ' Melvin V. First. Harvard University .; ; - p. 92, "90-95$ of ingested lead is eliminated promptly . in feces". .. ;! ,: .Robert J. M. Horton. M.D., PHS | .'n o.::: .. ;:- p. 133-139, Sources of lead polution,.Air - Food - Veter : .rv Robert J. M. Horton. M.D., ?KS v- v p. 14.0, "Cigarettes represent a modest but common source of lead". . ' ' .' ' V . ' , . Top of p. 146.' Dr. Kehoe says lead burden .has actually ' gone down In recent years. Goldvater'at VHO says saEsing similarity of the levels for urine and blood over past . two decades. ' '' - , ' \ .' ;.V ;* J'> if:?'yit -r : 21 22. 23. 24- 26. 27. 2S. 29. 30. 31. 33. - 3- p. 14.6, Cholak - remarkable similarity in findings in both their urine and blood lead content (1943-1962) Bottom p. 146, Dr. Lloyd Tenner1s - "extremely unlikely of systemic poisoning from entry of inorganic lead com pounds through the intact skin". Top p. I47, He considers lead tetraethyl and tetramethyl os absorbable through skin. Sr. Robert A. Kehoe Top of p. 150, "not the slightest suggestion of a pro gressive increase in the quantity of lead in body", 3 yrs. to -97 yrs. . Dr. Robert A. Kehoe1s Summary, p, 155 "ingestion 0.12-0.35 mg./day normally Mid p. 155, urine vs. blood Bottom p. 155 "even vith added lead in diet to 0.53 mg,/day. -- "slight trend toward increase in urine and none in blood". p. 156, Gives amounts of lead that must be ingested to cause poisoning, "soluble lend", note insoluble is excreted in feces. Norton Kelson. N. Y. University Medical Center p. 16(3, "agreement on critical features of lead poisoning and blood and urine levels and thres holds" . Norton Nelson. N. Y, University Medical Center Bottom p. 172, "by raeanp of atomic absorption the cost of time of lead in urine has been reduced -a minute or tvo at a very low cost". OTHER REFERENCES Cutis - p. 171-176, Voi. 1. No. 4, May 1965, Alexander A. Fisher, M.D. Paraphenylene..... Lead Industries Association, Inc., Facts about lead and Industrial Hygiene, p. 5. Trace Metals Research L&boratoiy, November 1, 1966 Private communication. KE 00i3It)a