Document EmXEgy1brnndL5bxwwY6gwEyn

FILE NAME: Chemical Abstracts (CHAB) DATE: 1968 DOC#: CHAB060 OCUMENT DESCRIPTION: Abstract Originally Published in 1966 by Smither Pierre Gervais (Univ. of Paris). Occupational Health Rev. 17(1), 19--24( 19G5)(Liiiti). The principal clictn. reactions, industrial uses, and toxicological studies of epoxy resins are reviewed. Sen sitization tests were conducted in guinea pigs witli an epoxy resin (Kpieote 87..''Shell) and a versatuidc hardener ( I'olyainidv-Gen eral Mills). Tests of animals sensitized with the resin and a hardener alone were neg. A pus. reaction was obtained when Freund adjuvant was used in conjunction with the resin, neg. with the hardener. Epoxy substances evidently provoke sensi tization to the extent that they are capable of covalent linkage <>) the proteins. When elementary precautions are taken, it is _ worker to develop silicosis of the 2nd stage of severity, and 10, 1 1 , and H years in the polymetal, Pb-Zn, and Mo mines to also get tuberculosis, none of the latter being found among workers of Au the mine. Complete quant, analysis revealed the presence in the dusts of the polymetal, Pb-Zn, and Mo mines of various amts, of 15-17 elements, while dust from the Au mine had only admixts. of 0.05% SbjOj and 0.20% As2Oj . iixpts. on animals (no details given) revealed that mine dusts of complex coinpn. caused intensive silicosis with pronounced exudative processes in the bronchi and alveoli. A. A. Horvath always possible to avoid the dermatitis due to industrial handling American Society for Testing and Materials: Air Pollution of hardeners and resins. P. J. Parisek Measurement Methods (ASTM Special Technical Publication, Damage to health by thorium and thorium-containing ma No. 352). Philadelphia: ASTM. 19G3. 77 pp. terials. G. Irmschcr. Proc. Natl. Conf. .-Icroso/s, 1st, IAblice Peregud, Eva Abramovna, and Gemet, E. V.: Khimicheskii near Prague 1962, 485-90(Pub. 19G5)(Ger). personnel prior to 1939 were exposed to ThOs Petroleum refinery dusts and the radia- b Analiz Vozdukha Promyshlennykh Predpriyatii; Rckomen- tion from Th and its decay products by virtue of its use in a con duetnye Metody Opredeleniya Predcl'no Dopustimykh Kontsentratsii Vrednykh Veshchestv v Vozdukhe (Chemical Analysis of tact-catalyst mixt. having diatomaceous earth as the matrix. Air of Industrial Installations; Recommended Methods of Deter Max.of 360 X 10"%c.of thoron/cm.5anddosesof30mr./hr.were measured in the involved areas of the plant; often the workers, mining the Limits of Permissible Concentration of Harmful Sub clothes were contaminated. Three persons exposed to these con stances in Air). Leningrad: Khimiya. 1965. 3G3 pp. ditions died with chronic interstitial pulmonary fibroses, and -- Spent,'.er, Guenter: Die Schwefeloxyde in Rauchgasen und in metaplasia of the pulmonary epithelial cells; on had a peripheral der Atmosphacre: Ein Problem der Luftreinhaltung (Sulfur epithelioma. Direct causality admittedly could not be estab Oxides in Flue Gas and in the Atmosphere: A Probletn of Keep lished, but it was felt that the superposition of radioactive ma ing the Air Pure). 2nd ed. Dsseldorf: VDI-Verlag. 1965. terials upon the known fibrogenic capacity of silica dusts was 186 pp. DM 19.80. most prone to produce the observed pulmonary changes. H. D. Bruner c Asbestos, asbestosis, and mesothelioma of the pleura. W. J. Smither. Proc. Roy. Soc. Med. 59(1), 57-9(19GG)(Eng). The chein. and phys. properties of various forms of asbestos (I) and the palhol. aspects of asbestosis are described in relation to con tact with different forms of I. W. C. Tobie _ Peculiarities of hygiene conditions and degree of safety against exposure to silicosis in some Kazakhstan mines. V. /,. Kha- mitova. Tr. Kazakhsk. Inst. Kracvoi Palol., Akad. Med. Nauk SS.SR 14, 22-7(1965)(Russ). The environmental conditions in the Lcninogorsk polymetal and Zyryanovsk Pb-Zn combines, and in the Eastern Kounrad Mo and Bes-Tubinsk Au mines, were d studied over a 10-17-year period, including the amt. and compn. of dust in the air of the shafts under various operational setups, as well as the records of periodical medical exarnns. of the workers, and of some cxptl. work on animals exposed to the par ticular dusts. The main source of dust generation was traced to the drilling and blasting operations, which, through the intro-- ' See also: Sewage and Wastes, Section 23. Pesticides, Section 72. Cosmetics and toiletries (Alexander) 29. Oxime of 2-(Nphenacyl-N,fV'-diethylaraino)ethyl beuzilate chloride--a new antidote against organophosphorus poisoning (Blete) 35. Precautions in work with a radioactive substance [ThOj] (Pujol) 59. Losses of tropane alkaloids during their isolation from biol. material (Akopyan) 60. Some chromatographic problems in chcm. toxicology of alkaloids--simple soln. (Fiori) 60. Mineral metabolism in sheep Iupinosis--Cu (Gardiner) 64. Distribution of radioactive I in thyroid gland and blood in distinct form of silicosis (Nurmagambetov) 66. Adrenal cortical function in cxptl. alcoholism in dogs (Ellis) 66. Effect of influenza virus on detoxi cation of hcllebrin (Link) 66. Inhibition of MeOH metabolism in mice with acetylsalicylic acid (Hassan) 68. Pharmacodynamic effects [of vitamins) in clearing the lungs [of dusts] (Schiller) 68. Spe"ies differences in toxicity of schistosomicide AUUQTT-16612 (Kimura) 68. Spectrophotolluorimetric method for Guthion residues in milk und animal tissues (Adams) 70. Photolluori- duction of wet drilling and intensive ventilation in blasts, re nietric method for del, of muretin (AMiydroxynuphthalimide duced the amt. of dust in the air of the shafts to the permissible diethyl phosphate) residues in animal tissues (Anderson) 70. norm of 3-5 m g./m .1 from the original figures for the 4 mines of Nature and extent of Guthion residues in milk and tissues result 50, 28, 85, and 50 m g./m .3, resp. The av. particle size of the ing from treated forage (Everett) 70. Comparative metabolism dust depended on the mode of the mining operation, rock drilling of 2,6-dichlorothiobenzamidc (Prefix) and 2,6-dichlorobenzo- producing 69% of dust of particle size <2 u, as against 47% for the nitrile in dog and rat (Griffiths) 71. Toxicity of paraquat and dust from drilled, blasted rock, and 53.3% in scraper transport dust. The Si02 content in the dusts of the 4 mines averaged 48.9, 45, 65, and 49.1%, resp. Examn. of the health records re vealed that it took an av. of 8, 9, 5, and 13 years, resp., for a diquat (Howe) 71. Hydrogen content of the air (Kershaw) 16. Detn. of cantharidin in tissues and its subcellular location (Bagatell) 60. Microradiographic detn. of Pb in mineralized tissues (Philipson) 60. 70-- FOODS W ILLIAM HORWITZ AND EDITOR EM ERITUS H. A. LEPPER Rapid method for the determination of manganese in food. Johann Firbas B., Giulio Vaceari H., and Luis Silva R. Bol. Soc. Quint. Peru 31(2), 57-G6(19G5)(Span). The A.O.A.C. method for Mil in food was simplified. Samples contg. 50-425 *. Mn were first ashed in 5% ale. Mg(OAc)2, then heated to 910 until a white ash was obtained. The cold residue washeated for 2-3 min. in 5 ml. of 1:1:1 H20-85% HP04-65% HNOs until dissolved. Three to 4 ml. H20 was added, filtered, and washed 3-4 times with hot H20 . To the combined filtrates and washings were added 5 ml. of 1% K I0 4in 20% H|PO< and 1 ml. of standard soln. of M11 contg. 100 7/ 111I. After 2 min. heating, the cooled soln. wasdild. to 25 ml. with H20 , and analyzed spectrophotometrically at 540 mu. Optimum results were ob tained with samples contg. 2-17 y Mn/ml. 23 references. V. G. Moss Enzymic proteolysis of raw and steamed meat. Aiko Kasugai (Women's Univ., Osaka, Japan). Biyo To Shokuryo 17(6), 387-95(1965)(Japan). Minced raw or steamed foods (1-3 g.) (meats, poultry, seafoods, egg, cereals, and legumes) were incu bated overnight at 30 with 20 ml. of enzyme soln. which con tained 0.2 or 0.3% of com. enzyme powder (from Rhizopus niveus, Aspergillus niger, Bacillus subtilis, and pancreatin). The amt. of Cl3C C02H-sol. fraction was given as tyrosine cquiv., analyzed by Foliti reagent. The amt. of amino acid liberated was detd. using ninhydrin. In seafoods, raw materials were more digestible than steamed ones, except bream and shrimp treated with enzyme from A . nigcr\ a similar tendency was ob- after heat treatment, because of the inhibitory action of raw egg, esp. egg white. The digestibility of cereals and legumes was slightly improved with heat treatment. Katuhiko Noda Reduction of aromatic nitro groups during acid hydrolysis in presence of carbohydrates. V. Handwcrck, E. Bujard, and J. Mauron (Lab. Recli. Produits Nestle, La Tour-dc-Peilz, Switz.). Helv. Chim. .4c/a 49(1), 419-23(1966)(Fr). The considerable loss of e-(2,4-dinitrophenyl)lysine during its acid hydrolysis in the presence of many foods was due to the action of carbohydrates which reduce the nitro group to the amino group. This has been demonstrated by the absence of this loss during hydrolysis without any added carbohydrates, or in pres ence of nonreducing carbohydrates. Aromatic nitro compds. were reduced to the amino compds. by hydrolysis with tiN HC1 in presence of reducing carbohydrates. N, A. Abraham Flavonoids in food technology. Piotr Lewicki (Katedra Technol. Przemyslu Rolno-Spozywczego Szkoly Glownej Gos- podarst. Wiejskiego, Warsaw). IViadomosci Chetn. 20(1), 47- 58(1966)(Pol). A review of the chemistry and biosynthesis of flavonoid compds., their distribution in edible plants, and their influence on organoleptic properties of food. 34 references. SXTT Food additives. Cross-linked polyester resins. Anon. Fed eral Register 31, 290 (Jan. 11, 1960)(Eng); cf. C.-l 63, 15434A. The previous regulation under the Federal Food, Drug, and Cos metic Act is revised to provide for the use of the addnl. com ponent from 4.4'-isonronvli(lencrtir>hrn,,t mill vrlrtn in