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March
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Mr. Jacob Rassner
Rassner and Rassner
15 Park Row .
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Hew York, Hew York 10033
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Dear Mr. Rassner: ~ :
I have delayed in writing to you on the subject of our correspondence in
Hovember, 1975 for the reason that I expected time to yield the
answer to a question which arose out of pour description of a case,
presumably, of tetra-ethyl-lead poisoning. Unfortunately, I am
somewhat disabled by ocular difficulties and find it necessary to
extend myself as little as possible, and I simply waited for your
further report on your patient in the feeling that time alone would
answer my question more satisfactorily then it could be answered
otherwise. Tetra-ethly-lead poisoning is an intoxication which I
have investigated more throughly than has any other person. Hot
that I or anyone else knows all that is to be known about it.
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I refer here to your statement that your patient had(at the time you wrote) "Myasthenia gravis" following an acute exposure to this ehcmical compound (in a mixture of chemicals for use in treating gasoline.) Having had to deal with the first series of cases of this type seen in industry, and with occasional cases since, I recognize the likelihood of the development of this clinical entity as a part of the picture of this acute (not necessarily lethal) intoxication.
This syndrome lasts for a fairly long time, in some instances for months, presumably until the lead compound, (which is absorbed into, among other tissues, the central ner$gajissystem) ^ been excreted
from the body. In some instances, recovery of a complete type does not occur. Rather, the individual may remain disabled to some extent indefinitely. However, this is not usual and I sincerely hope in your case it does not. Hot only for the sake of your patient,
but also since my waiting will have been in vain. I am inclined to
the belief that if this type of result develops, the difficulty is more in the nature of a neurosis than evidence of nervous system pathology, that is, of destructive injury to the nervous system. I say this because "myasthenia gravis", generally is regarded as an
Mr. Jacob Rassner,
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March 9, 1976
incurable lesion, whereas, tetra-ethyl-iead poisoning in my opinion is either a promptly lethal disease, or a prolonged one, but c c u r a b e (spontaneously curable) one. That is, there in no specific traetment which can reliably be recommended, except that the patient often requires cozitinuous medical supervision.
I would appreciate .your writing to me and reporting as well as you can on the present state of this patient. If his doctor should wish to
do sof I shall be happy to hear from him.
CordialT. yours,
RAn: .if:
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lidon
0005654
R a s s n e r a n d Ra s s n e r
COL'NSKLLORS AT LAW PROCTORS INADMIRALTY
.iacoh ras sner AlAN C. RASSNER ERNEST RASSNER <1904-1970) iiliOHOE O. KILARJIAN 1-RANCIS J.NICOSIA
N ovem ber 28, 1975
15 PARK ROW - NEW YORK, N. Y. 10058
212 Barclay 7-2618
Robert A. Kehoe, M.D. University of Cincinnati Medical Center 3223 Eden Avenue Cincinnati, Ohio 45267
My dear Dr. Kehoe
I acknowledge with appreciation receipt of your recent letter regarding my inquiry.
Hopefully, you may find the time to be able to let me have some further information on the subject.
Thank you very much for your indulgence in this matter.
JR: A
Sincerely JACOB RASSNER
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