Document EOK14LM1zVGL5XRZg2YNN7LN

https://www.cdc.gov/exposurereport/pfas_early_release.html Early Release: Per- and Polyfluorinated Substances (PFAS) Tables, NHANES 20112018 CDC routinely updates summary measurements for its National Health and Nutrition Examination Survey (NHANES) biomonitoring data in Updated Tables to the National Report on Human Exposure to Environmental Chemicals (National Report). CDC is providing these per- and polyfluorinated substances (PFAS) serum measurements as a standalone resource in advance of the next scheduled National Report update to aid federal, state, and local public health agencies, and others, currently investigating PFAS. These tables present biomonitoring data gathered in up to four cycles of CDC's NHANES: survey years 2011-12, 2013-14, 2015-16, 2017-18. The NHANES survey is designed to provide nationally representative information for the general U.S. population. PFAS were measured in serum from random one-third subsamples of NHANES participants. The Environmental Health Laboratory in CDC's National Center for Environmental Health used mass spectrometry methods to make these measurements. The measurement of an environmental chemical in a person's blood is an assessment of exposure; it does not by itself mean that the chemical causes disease or an adverse effect. Research studies, separate from these data, are required to determine which blood concentrations are safe and which ones could be associated with disease or an adverse effect. Please direct any questions about this information to CDCINFO: https://wwwn.cdc.gov/dcs/contactus/form Notes and Additional Resources For more information about PFAS, please see the following factsheet: https://www.cdc.gov/biomonitoring/PFAS_FactSheet.html Statistics include geometric means and selected percentiles, with 95 percent confidence intervals around each estimated statistic. Percentiles describe the shape of the distribution. For all chemicals, the 50th, 75th, 90th, and 95th percentiles are presented. Biomonitoring is the assessment of human exposure to chemicals by measuring the chemicals, their metabolites, or adducts in human specimens such as blood, serum, or urine. Data Tables Serum 9-Chlorohexadecafluoro-3-oxanonane-1-sulfonic acid (2017 - 2018) Serum Adona (ammonium salt of 4,8-dioxa-3H-perfluorononanoic acid) (2017 - 2018) Serum GenX (ammonium salt of 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3- heptafluoropropoxy)-propanoic acid (HFPO-DA)) (2017 - 2018) Serum Perfluorodecanoic acid (PFDA) (2011 - 2018) Serum Perfluoroheptane sulfonic acid (PFHpS) (2017 - 2018) Serum Perfluorohexane sulfonic acid (PFHxS) (2011 - 2018) Serum Perfluorohexanoic acid (PFHxA) (2017 - 2018) Serum Perfluorohexanoic acid (PFHxA) (2017 - 2018)- NOT Detected CAS Number 307-24-4 Geometric mean and selected percentiles of serum concentrations (in g/L) for the U.S. population from the National Health and Nutrition Examination Survey. Demographic Survey Geometric mean 50th Percentile 75th Percentile 90th Percentile 95th Percentile Categories (years) (95% CI) (95% CI) (95% CI) (95% CI) (95% CI) Total population 17-18 * <LOD <LOD <LOD <LOD Age 12-19 years 17-18 * <LOD <LOD <LOD <LOD Age 20+ years 17-18 * <LOD <LOD <LOD <LOD Males 17-18 * <LOD <LOD <LOD <LOD Females 17-18 * Mexican Americans 17-18 * <LOD <LOD <LOD <LOD <LOD <LOD <LOD <LOD Non-Hispanic 17-18 * blacks <LOD <LOD <LOD <LOD Non-Hispanic 17-18 * whites <LOD <LOD <LOD <LOD All Hispanics 17-18 * <LOD <LOD <LOD <LOD Asians 17-18 * <LOD <LOD <LOD <LOD Limit of detection (LOD, see Data Analysis section) for Survey year 17-18 is 0.100. <LOD means less than the limit of detection, which may vary for some chemicals by year and by individual sample. * Not calculated: proportion of results below limit of detection was too high to provide a valid result. Serum Perfluorononanoic acid (PFNA) (2011 - 2018) Sample size 1929 313 1616 952 977 297 430 667 473 257 Serum Perfluorooctanoic acid (PFOA) (2011 - 2018) Serum Perfluorooctanoic acid (PFOA) (2011 - 2018) - DROPPING Sum of linear and branched PFOA isomers Geometric mean and selected percentiles of serum concentrations (in g/L) for the U.S. population from the National Health and Nutrition Examination Survey. Demographic Survey Geometric mean 50th Percentile 75th Percentile 90th Percentile 95th Percentile Categories (years) (95% CI) (95% CI) (95% CI) (95% CI) (95% CI) Total population 11-12 2.08 (1.95-2.22) 2.08 (1.96-2.26) 3.03 (2.76-3.27) 4.35 (3.82-4.85) 5.68 (5.02-6.49) Total population 13-14 1.94 (1.76-2.14) 2.07 (1.87-2.20) 3.07 (2.67-3.37) 4.27 (3.57-5.17) 5.57 (4.60-6.27) Total population 15-16 1.56 (1.47-1.66) 1.57 (1.47-1.77) 2.47 (2.27-2.57) 3.37 (3.07-3.57) 4.17 (3.87-4.67) Total population 17-18 1.42 (1.33-1.52) 1.47 (1.37-1.57) 2.07 (1.97-2.30) 2.97 (2.77-3.37) 3.77 (3.17-5.07) Age 12-19 years 11-12 1.80 (1.71-1.91) 1.74 (1.67-1.89) 2.41 (2.17-2.62) 2.93 (2.68-3.19) 3.59 (2.93-4.25) Age 12-19 years 13-14 1.66 (1.50-1.84) 1.67 (1.37-1.97) 2.20 (1.97-2.57) 2.87 (2.57-3.40) 3.47 (2.87-4.37) Age 12-19 years 15-16 1.25 (1.14-1.37) 1.27 (1.17-1.47) 1.67 (1.47-1.87) 2.07 (1.77-2.57) 2.47 (2.07-2.97) Age 12-19 years 17-18 1.18 (1.06-1.31) 1.17 (1.00-1.37) 1.67 (1.37-1.97) 2.07 (1.77-2.37) 2.37 (2.00-2.97) Age 20+ years 11-12 2.12 (1.98-2.28) 2.16 (2.01-2.33) 3.15 (2.90-3.36) 4.64 (3.93-5.25) 5.94 (5.34-7.45) Age 20+ years 13-14 1.98 (1.79-2.19) 2.07 (1.90-2.27) 3.17 (2.77-3.47) 4.47 (3.70-5.27) 5.60 (4.67-6.40) Age 20+ years 15-16 1.60 (1.51-1.71) 1.67 (1.57-1.87) 2.47 (2.37-2.67) 3.47 (3.17-3.67) 4.27 (4.07-4.97) Age 20+ years 17-18 1.45 (1.35-1.56) 1.47 (1.37-1.57) 2.17 (1.97-2.37) 3.17 (2.77-3.57) 3.87 (3.27-5.17) Males 11-12 2.37 (2.22-2.53) 2.38 (2.26-2.56) 3.25 (3.00-3.56) 4.61 (4.11-5.02) 5.62 (4.85-6.20) Males 13-14 2.29 (2.09-2.50) 2.37 (2.17-2.57) 3.27 (2.87-3.60) 4.67 (3.77-5.60) 5.67 (4.67-6.27) Males 15-16 1.80 (1.66-1.94) 1.87 (1.67-2.07) 2.57 (2.40-2.67) 3.37 (3.07-3.67) 4.07 (3.67-4.87) Males 17-18 1.61 (1.50-1.73) 1.57 (1.47-1.77) 2.17 (2.07-2.37) 3.17 (2.77-3.50) 3.77 (3.27-5.17) Females 11-12 1.84 (1.68-2.01) 1.78 (1.62-1.98) 2.65 (2.34-3.14) 3.91 (3.36-4.99) 5.68 (4.33-8.45) Females 13-14 1.66 (1.48-1.87) 1.67 (1.47-1.87) 2.67 (2.27-3.07) 3.77 (3.37-4.70) 5.07 (4.07-6.70) Females 15-16 1.36 (1.29-1.45) 1.37 (1.27-1.47) 2.17 (1.97-2.47) 3.37 (2.87-3.67) 4.17 (3.67-4.97) Females 17-18 1.26 (1.17-1.36) 1.27 (1.17-1.37) 1.97 (1.77-2.20) 2.97 (2.57-3.37) 3.77 (2.97-5.07) Mexican Americans 11-12 1.66 (1.37-2.02) 1.71 (1.32-2.23) 2.43 (1.98-2.98) 3.38 (2.43-4.48) 4.08 (2.98-6.15) Mexican Americans 13-14 1.36 (1.25-1.47) 1.37 (1.27-1.47) 1.97 (1.87-2.10) 2.70 (2.40-3.10) 3.17 (2.57-3.77) Mexican Americans 15-16 1.14 (1.01-1.28) 1.17 (1.07-1.27) 1.67 (1.47-1.87) 2.47 (1.87-2.97) 2.77 (2.20-4.67) Mexican Americans 17-18 1.11 (.967-1.27) 1.17 (.870-1.37) 1.57 (1.37-1.87) 2.17 (1.87-2.37) 2.80 (2.37-4.20) Non-Hispanic blacks 11-12 1.80 (1.71-1.90) 1.94 (1.76-2.09) 2.82 (2.65-2.95) 3.94 (3.51-4.40) 5.11 (4.40-5.79) Non-Hispanic blacks 13-14 1.52 (1.34-1.73) 1.67 (1.37-1.97) 2.57 (2.17-2.97) 3.60 (3.07-4.50) 4.60 (3.40-5.77) Non-Hispanic blacks 15-16 1.36 (1.21-1.53) 1.37 (1.27-1.57) 2.17 (1.97-2.57) 3.37 (2.77-3.77) 4.07 (3.57-5.27) Non-Hispanic blacks 17-18 1.18 (1.08-1.30) 1.27 (1.07-1.47) 1.77 (1.67-1.97) 2.70 (2.27-2.97) 3.37 (2.77-4.27) Non-Hispanic whites 11-12 2.25 (2.05-2.47) 2.25 (1.98-2.48) 3.21 (2.90-3.50) 4.68 (3.95-5.35) 6.20 (5.34-7.74) Non-Hispanic whites 13-14 2.20 (1.91-2.52) 2.27 (1.97-2.67) 3.37 (2.77-3.77) 4.77 (3.77-5.67) 5.77 (4.80-6.87) Non-Hispanic whites 15-16 1.69 (1.57-1.82) 1.77 (1.57-1.97) 2.57 (2.47-2.67) 3.47 (3.17-3.67) 4.47 (3.87-5.17) Non-Hispanic whites 17-18 1.54 (1.41-1.69) 1.57 (1.37-1.77) 2.27 (2.07-2.47) 3.17 (2.77-3.67) 3.77 (3.07-5.47) All Hispanics 11-12 1.70 (1.48-1.95) 1.79 (1.59-1.95) 2.46 (2.15-2.91) 3.60 (2.95-4.48) 4.70 (3.87-5.94) All Hispanics 13-14 1.45 (1.33-1.59) 1.47 (1.37-1.67) 2.10 (1.97-2.40) 3.07 (2.67-3.27) 3.47 (3.17-3.97) All Hispanics 15-16 1.25 (1.14-1.36) 1.27 (1.17-1.47) 1.87 (1.67-2.20) 2.67 (2.37-3.07) 3.17 (2.77-4.17) Sample size 1904 2165 1993 1929 344 401 353 313 1560 1764 1640 1616 966 1031 964 952 938 1134 1029 977 211 332 370 297 485 455 439 430 666 861 619 667 406 537 629 Demographic Survey Geometric mean 50th Percentile 75th Percentile 90th Percentile 95th Percentile Categories (years) (95% CI) (95% CI) (95% CI) (95% CI) (95% CI) All Hispanics 17-18 1.19 (1.07-1.32) 1.27 (1.07-1.37) 1.67 (1.47-1.87) 2.37 (2.07-2.67) 2.97 (2.50-4.37) Asians 11-12 2.08 (1.83-2.36) 2.21 (2.04-2.27) 2.92 (2.55-3.45) 4.66 (3.42-5.79) 5.79 (4.93-8.91) Asians 13-14 1.97 (1.75-2.23) 1.87 (1.67-2.27) 2.97 (2.47-3.57) 4.67 (3.97-5.77) 5.90 (5.00-6.40) Asians 15-16 1.66 (1.42-1.94) 1.77 (1.37-2.07) 2.37 (2.17-2.87) 3.77 (2.97-4.47) 4.77 (3.87-7.57) Asians 17-18 1.65 (1.38-1.97) 1.50 (1.37-1.77) 2.67 (2.07-3.40) 4.67 (2.57-9.87) 6.77 (3.40-17.0) Limit of detection (LOD, see Data Analysis section) for Survey year 11-12 is 0.1. See Calculation of PFOS and PFOA as the Sum of Isomers for additional information about Survey years 2013- 2014, 2015-2016, and 2017-2018. Serum n-Perfluorooctanoic acid (n-PFOA) (2013 - 2018) Serum branched Perfluorooctanoic acid (Sb-PFOA) (2013 - 2018) Serum Perfluorooctane sulfonic acid (PFOS) (2011 - 2018) Serum n-Perfluorooctane sulfonic acid (n-PFOS) (2013 - 2018) Serum branched Perfluoromethylheptane sulfonic acid (Sm-PFOS) (2013 - 2018) Serum 2-(N-Methyl-perfluorooctane sulfonamido) acetic acid (Me-PFOSA-AcOH or Me-FOSA-A) (2011 - 2018) Serum Perfluoroundecanoic acid (PUFA or PFUnDA) (2011 - 2018) Top of Page Page last reviewed: February 2, 2021 Content source: Centers for Disease Control and Prevention Sample size 473 291 234 220 257