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AR226-2876 Material Tested ..a.s-'.'swa^tsp-.ByHitt-S!?-;"-',-;:^----'' -"l-.*ai3|^^y^^<^^?^''^w^e;a2~^K"f^K^"^^^^ '^--^' Copies to: E. I. du Font de Nenours and Company Haskell Laboratory for Toxicology and Industrial Medicine HASKELL LABORATORY REPORT NO. 52-79 Haskell No. 12,402 Other Codes Sample Ready for Testing 7/6/78 Material Chemicals, Dye Jackson Labora Chambern Works Procedure: The test material, as a 50% suspension in acefopne/corn oil 15:<85 or 7.5:92.5, uas adBinist intubation to a group of 10 young adult ChR-CD male ^rata at a repeated dosage level of 3,400 g/kg/day group of 10 rats served as controls and was in&ubated with acet&.ie/com oil 15:85 or 7.5:92.5. Eight before ehe fifth dose and the remaining two Ctest rats were sacrificed the day after the fourth dose. were sacrificed after the fourth dose. Four of the remaining eight controls were sacrificed after the remaining four were sacrificed after a l|4da^ recovery 'i?xfe831;6di.** The test material, as an 18Z suspension in acetone/corn oil 15:85, was administered by intragast group of 10 young adult ChR-CD male rats; at a repeated dosage level of 1,700 ag/kg/day; an additional served as controls and was Intubated with acetone/corn oil 15:85. Ten test rats died before the sixth rats were sacrificed after the seventh dose and the remaining eight controls were sacrificed without p The test material, as a 72 suspension in acetone/corn oil 15:85, was administered by intragastric group of 10 young adult ChR-CD male rats at a repeated dosage level of 850 g/kg/day; an additional g served as controls and was Intubated with acetone/corn oil 15:85. Four test rats died before the ten of the remaining six test rats were sacrificed approximataly four hours after the tenth dose and thre recovery period. Five control rats were sacrificed after the tenth dose and the remaining five contr after a 14-day recovery period. iijiteii iaii!'!"a|t|t>aiiiiiltd..iit.lv4>.,,,,,ii;i. Company Sanitized. 0) ^5 h U 4J s-s O -H St; .28 a w 5S 5S a o Ss a a ^^ 8w 5w ^ff* " W a ^ . a Sf 4 - i u ^'s 2" s s rf u i 5 ?1 'ss V &0 II g-^ a u u a w ? 8-S h a) u r-l B H ^i fc a 45 1 ',5a, M o g 0 0<i ^ 5 B 4J 5 y s 4J a 0 0 0 1-1 1-1 $ 00 ^>j o a 0 'T a . co &a (M ft A f-1 ^ 0 0 Q in 1^ oo CD 0 < 0 (A ^"5e o OT 0) 0 a o a> N W >> / Company Sanitized. Does not contain TSCA ffB r- - 3 LH:vlm Pate Issued: March 16, 1979 Report by; 7Af701il. 1..A'^J ----H t.IfM-1F Lonnie Hirackle Technician Approved by: J^v.^ ^ fcG--era--ld^f._K_e_nn_e_dy____ Chief, Acute Inveetigatlons