Document DvwoLz90VqDq40Z4eNzL8BvNo

WVU :: Printer Friendly: WVU :: School of Medicine :: Community Medicine :: C8 Page 1 o f 1 Printed from: http://www.hsc.wvu.edu/som/cmed/c8/results/C8AndPFCLevels/index.asp Page Printed: April 7, 2008 WVU :: School of Medicine :: Community Medicine :: C8 C8 Health Project Results C8 & Other PFC Levels The tables and graphs on this page (links below) are summary results for the plasma concentrations of C8 and C8 Sulfonate of the participants in the C8 Health Project. These results include participants from whom a sufficient and viable plasma sample was obtained. Plasma concentrations are presented for the overall population, as well as stratified by common demographic characteristics. Demographic data used for age, gender, education and income were those provided by the participants during the completion of the survey. The accuracy of the demographic summaries reflects the accuracy of the responses provided by the participants. The qualifying water district is the water district for which the participant presented the requisite qualifying documents to be eligible to participate in the C8 Health Project. This "qualifying" water district may or may not reflect the water district or source of exposure to C8 or other PFCs. This concept is important to understand, because "peer review" efforts may take more elaborate approaches and show slightly different geographic distributions. Results for all participants with detectable levels of C8 and C8 Sulfonate are included in the summary tables and charts on this page. Subsequent reports may use different inclusion/exclusion criteria, population substrata, etc. Small differences can result from such particular analytic decisions. The summary results reported here, then, represent a synopsis that adds to existing knowledge, and which may be further refined by far more detailed work that will be submitted to peer-review journals. Few, if any, previous human studies of PFCs of this magnitude have been conducted. And, while this is clearly a unique population, little is known about what level is considered to be "acceptable" or "dangerous." Seeking the answer to such questions is, in part, the purpose of the C8 Health Project and the mission of the Science Panel. All graphs and tables were prepared by the WVU School of Medicine and are copyrighted. Si Download Abobe Reader C8 & C8 Sulfonate Plasma Concentrations - Population Summary (58 KB) C8 & C8 Sulfonate Plasma Concentrations Stratified by Age & Gender (44 KB) C8 & C8 Sulfonate Plasma Concentrations Stratified by Qualifying Water District (41 KB) C8 & C8 Sulfonate Plasma Concentrations Stratified by Education (39 KB) C8 & C8 Sulfonate Plasma Concentrations Stratified by Income (45 KB) http://www.wvu.edu/PrintableVersion/ 4/7/2008 Population Results for C8 and C8 Sulfonate Plasma Concentrations All Age and Gender Groups Mean Std. Error o f Mean M e d ia n Mode Std. Deviation V a ria n c e M inim um Maxim um Percentiles 25 50 75 Statistics C8 C8 Sulfonate 82.9848 23.3571 .93136 .06010 28.2000 9.60 240.82333 57995.875 20.2000 16.60 15.50915 240.534 .50 22412.00 13.4000 .50 759.20 13.9000 28.2000 20.2000 70.6000 29.0000 Population Distribution of C8 Concentration 2003 West Virginia University School of Medicine Frequency Population Distribution of C8 Suifonate fledian Values for C8 and C8 Sulfonate Based on Quarter of Participation C8 (ng/ml) C8 Sulfonate (ng/mi) 2008 West Virginia University School of Medicine Median Population Results for C8 and C8 Sulfonate Plasma Concentrations Stratified by Age & Gender Groups Age Category <10 Years 10-19.9 Years 20-29.9 Years 30-39.9 Years 40-49.9 Years 50-59.9 Years 60-69.9 Years Mean M e d ia n M inim um Maxim um Std. Deviation Std. Error o f Mean Mean M edian M inim um M axim um Std. Deviation Std. Error o f Mean Mean M edian M inim um M axim um Std. Deviation Std. Error o f Mean Mean M e d ia n M inim um M axim um Std. Deviation Std. Error of Mean Mean M e d ia n M inim um M axim um Std. Deviation Std. E rror o f Mean Mean M edian M inim um M axim um Std. Deviation Std. Error o f Mean Mean M e d ia n M inim um Maxim um Std. Deviation Std. Error o f M ean C8 80.7732 34.0000 .70 2070.60 131.97626 2.35785 63.0104 27.2000 .60 1236.60 99.93089 1.04321 45.8281 21.2000 .60 1102.60 79.42039 .79401 68.6560 22.4000 .50 8162.80 212.95424 2.08498 90.6931 27.8000 .50 17556.60 299.87368 2.74675 108.1281 33.5000 .50 8416.50 303.90537 2.95416 114.8070 42.7000 .60 22412.00 355.41953 4.25263 C8 Sulfonate 23.0641 20.0000 1.10 202.10 13.48214 .24098 22.4855 19.9000 .60 198.80 12.12196 .12668 19.9271 17.9000 .50 199.80 11.50305 .11528 20.4713 18.3000 .60 236.30 12.02323 .11799 21.9906 19.1000 .50 564.30 14.72075 .13511 25.2993 21.9000 .50 291.50 16.23525 .15804 28.9309 24.9000 .50 291.50 18.65860 .22380 ZOOS West Virginia University School of Medicine Age Category 70-79.9 Years 80+ Years T o ta l Mean M e d ia n M inim um Maxim um Std. Deviation Std. Error of Mean Mean M e d ia n M inim um M axim um Std. Deviation Std. Error o f Mean Mean M e d ia n M inim um Maxim um Std. Deviation Std. Error of Mean C8 113.5256 39.5000 .70 4751.50 227.82005 3.83175 104.2679 39.3000 .70 2299.10 197.64315 5.98095 82.9848 28.2000 .50 22412.00 240.82333 .93136 C8 Sulfonate 30.0827 25.6000 .50 759.20 25.27402 .42618 29.1912 24.6000 1.50 275.50 23.20182 .70406 23.3571 20.2000 .50 759.20 15.50915 .06010 Median C8 Concentrations for Age & Gender Groups "Gender* H Female Male Age Category 2008 West Virginia University School of Medicine Median C8 Sulfonate Concentrations for Age & Gender Groups 30.00- "Gandei" UFemale UMale Age Category 2008 West Virginia University School of Medicine Population Results for C8 and C8 Sulfonate Plasma Concentrations Stratified by Participant's Qualifying Water District All Age and Gender Groups Q ualifying W ater District M ason County, W V City of Belpre, OH Little Hocking W ater Association, OH Lubeck Public Service District, W V Tuppers Plains, OH Village o f Pom eroy, OH T o ta l Case S um m a ries C8 (Final Test C8S (Final Test Value; Num eric) Value; Num eric) Mean 14.5561 22.9114 M e d ia n 12.0000 19.7000 M inim um .60 .50 M axim um 525.20 274.90 Std. Deviation 11.58330 14.59610 Std. Error of Mean .10490 .13251 Mean 43.3626 23.2543 M e d ia n 27.1000 20.4000 M inim um M axim um Std. Deviation .50 7932.00 107.52400 .70 245.80 14.99425 Std, Error of Mean 1.16957 .16340 Mean M e d ia n 226.7114 132.4500 23.4114 20.3000 M inim um .60 .50 M axim um 22412.00 759.20 Std. Deviation 349.68251 15.68320 Std. E rror of M ean 3.11943 .14016 Mean M e d ja n 94.3865 45.9000 25.3850 22.1000 M inim um .50 .50 Maxim um 17556.60 291.50 Std. Deviation 325.29059 15.87031 Std. Error of Mean Mean 2.54172 39.5996 .12433 21.9942 M e d ia n 28.1000 18.9000 M inim um .50 .60 Maxim um 8162.80 585.20 Std. Deviation 86.44557 15.92322 Std. Error o f Mean .74184 .13679 Mean 14.0692 20.6339 M edian 11.5500 17.7000 M inim um .60 .60 M axim um 287.00 207.40 Std. Deviation 13.21007 13.92657 Std. E rror of M ean Mean M e d ia n .22209 82.8443 28.2000 .23437 23.3475 20.2000 M inim um .50 .50 Maxim um 22412.00 759.20 Std. Deviation 240.09476 15.46953 Std. Error o f Mean .92960 .06001 2008 West Virginia University School of Medicine Median C8 Values for Qualifying Water Districts 100.00- D) E <D O c so.oo- 25.0D- Mason County, City of Belpre, Little Hocking Lubeck Public Tappers Plains, Village of VW OH Water Service District, OH Pomeroy, OH Assoctsrtion, OH WV Qualifying Water District Median C8 Sulfonate Values for Qualifying Water Districts Mason County, City of Belpre, Little Hocking Lubeck Public Tappers Plains, Village of WV OH Wiater Service District, OH Pomeroy, OH Association, OH WV Qualifying Water District ) 2008 West Virginia University School of Medicine Population Results for C8 and C8 Sulfonate Plasma Concentrations Stratified by Years of Education All Age & Gender Groups Case Summaries "Y e a rs o f S ch o o l C o m p le te d " No Response Mean M e d ia n M inim um Maxim um Std. Deviation Std. Error of Mean <12 Years Mean M e d ia n M inim um M axim um HS Dipiom a or GED Std. Deviation Std. E rror o f M ean Mean M e d ia n M inim um Maxim um Som e C ollege Std. Deviation Std. Error o f Mean Mean M e d ia n M inim um M axim um Std. Deviation Std. Error o f Mean Bachelors Degree o r Higher Mean M e d ia n M inim um Maxim um Std. Deviation Std. Error o f Mean Total Mean M edian M inim um M axim um Std. Deviation Std. E rror o f Mean C8 74.6807 27.3000 .90 1976.90 147.11520 4.37448 71.1974 27.9000 .60 2523.80 133.69063 1.03833 93.2940 29.1000 .50 22412.00 315.30600 2.04805 85.1287 28.2000 .50 8416.50 230.75127 1.70838 72.0679 26.1000 .50 4751.50 176.05497 2.07411 82.9848 28.2000 .50 22412.00 240.82333 .93136 C8 Sulfonate 22.3976 19.2000 1.00 112.20 13.51821 .40268 22.8766 19.8000 .50 370.10 14.90438 .11595 23.8737 20.5000 .50 759.20 16.63157 .10826 23.1245 20.2000 .50 564.30 14.98843 .11121 23.5038 20.6000 .60 238.90 14.55838 .17176 23.3571 20.2000 .50 759.20 15.50915 .06010 2003 West Virginia University School of Medicine Median C8 Concentrations for Education Groups "Gender Femals H viale E 15) c 8 C(7 *5 S No Response <12 Years HS Diploma or Some College GED "Years of School Completed" Bachelors Degree or Higher Median C8 Sulfonate Concentrations for Education Groups 30.00- "Gender" Female Male 2008 West Virginia University School of Medicine Population Results for C8 and C8 Sulfonate Plasma Concentrations Stratified by Household Income All Age and Gender Groups Case Summaries "Average Household Income" C8 < $ 1 0 ,0 0 0 Mean 57.1410 M edian 22.1000 M inim um .60 Maxim um 1979.50 Std. Deviation 115.66904 $ 1 0 ,0 0 1 -$ 2 0 ,0 0 0 $20,001 - $30,000 $30,001 - $40,000 $40,001 - $50,000 $50,001 - $60,000 $60,001 - $70,000 Std. E rror o f Mean Mean M e d ia n M inim um M axim um Std. Deviation Std. E rror o f Mean Mean M e d ia n M inim um M axim um Std. Deviation Std. Error o f Mean Mean M e d ia n M inim um M axim um Std. Deviation Std. Error o f Mean Mean M e d ia n M inim um M axim um Std. Deviation Std. Error of Mean Mean M e d ia n M inim um M axim um Std. Deviation Std. E rror o f Mean Mean M e d ia n M inim um M axim um Std. Deviation Std. Error of Mean 1.34029 67.8230 24.8000 .50 2590.80 145.93333 1.55610 78.4169 27.6000 .50 3190.60 161.48672 1.68124 82.9654 29.0000 .50 7534.60 189.60938 2.10249 79.1755 28.5500 .60 4751.50 167.34416 2.05986 98.5455 30.6000 .70 22412.00 399.48548 5.35752 121.5587 35.1000 .50 17556.60 468.06639 7.05556 C8 Sulfonate 20.7658 17.9000 .50 291.50 14.39424 .16724 21.8999 18.8000 .50 585.20 16.17785 .17296 23.3989 20.2000 .50 274.90 15.00223 .15649 23.9769 20.7000 .50 564.30 16.94342 .18826 23.9217 20.9000 .50 272.00 14,75490 .18183 24.3102 21.4000 .60 289.40 15.13852 .20333 24.6619 21.8000 .60 225.00 14.49264 .21891 2008 West Virginia University School of Medicine "Average Household incom e" >$70,000 Mean M e d ia n M inim um M axim um Std. Deviation Std. Error of Mean Don't Know Mean M e d ia n M inim um M axim um Std. Deviation Std. Error of Mean Total Mean M e d ia n M inim um M axim um Std. Deviation Std. Error of Mean C8 105.9631 35.8500 .60 8416.50 307.99547 3.34738 75.9945 27.8000 .60 3713.20 155.38809 1.71274 82.9848 28.2000 .50 22412.00 240.82333 .93136 C8 Sulfonate 24.9478 22.2000 .60 207.40 14.38888 .15663 23.1615 19.6000 .70 759.20 16.83009 .18580 23.3571 20.2000 .50 759.20 15.50915 .06010 Median C8 Values for Household Income Groups "Gender" BFemale Male M edian C8 (ng/ml) "Average Household income" 2008 West Virginia University School of Medicine Median C8 Sulfonate Values for Household Income Groups 30,00- "Gender" iFemale M ale Median C8 Sulfonate (ngiml) 2008 West Virginia University School of Medicine