Document DMNRkQ079bEbE1qKZxb2O0y9o

GENERAL CHEMICAL EXPOSURE (X) MONSANTO STUDY - J. Killeen (3/78) SCOPE: - 365 former Monsanto employees. OBJECTIVES: - Proportional mortality analysis of cancer deaths by slca and occupational exposure. CONCLUSIONS: - No statistically significant excesses in (9) digestive categories. - No apparent prostate cancer excesses in department. - No prior reasons for suspecting excess genital, diges tive cancer deaths. - Non-statlstically significant excess in digestive genital cancer deaths. (2) NIOSH STUDY - R. Solrtaa (7/78) SCOPE: - 465 death certificates of 484 employee deaths between 1950 and 1976. OBJECTIVES: - Epidemiological study of employee deaths based upon FMR 6 PCMR by race, site, age, exposure period, and national origin. CONCLUSIONS: - Slight excess of digestive, genito-urlnary cancer, not associated to specific etlologlc agent. Not statisti cally significant when compared to Rampden county rates. XJCC 085672 0 GENERAL CHEMICAL EXPOSURE (Coat) (3) STUPY/VISIT BY PETERS/MQNSON (6/78? SCOPE: (OSilA Health Hazard Survey) - Analysis/Evaluation o (2) prior studies: Monsanto (Killeen) * NIOSH (Spirtas) OBJECTIVES: - Determine whether further studies or medical evaluations are necessary. CONCLUSIONS: - Data from both studies are consistent with no demonstrable effect of working at Springfield Plant In cause of death. (4) UNIVERSITY OF PITTSBURGH STUDY - MARSH (12/79) SCOPE: - 2490 total eohort of employees during period 1949 - 1966. OBJECTIVES: - Analyze long-term, cause-specific mortality patterns for Monsanto-Springfleld employees and ex-employees and com pare to mortality experience asiong general populations in U.5, Massachusetts., and Hampden County. CONCLUSIONS ' - Fever deaths from any cause ... less chan pxpected. - Fever deaths from all forms of cancer .than expected. - Slightly more deaths from digestive and genito-urinary cancers ... than expected. - No nev evidence was uncovered to show any worker-health problem at Springfield Plant. UCC 085673 GENERAL CHEMICAL EXPOSURE (Cone) (5) UNIVERSITY OF PITTSBURGH STUDY (3) MARSH flO/Sl) SCOPS: - 2479 total cohort of employees and ex-eaployees during parlod 1930 - 1976. OBJECTIVES: - Determine if any association exists between digestive, genito-urlnary cancers and certain chemical agents and/ or conditions specific to work environment. CONCLUSIONS: - Methodological problems, small numbers, and questionable exposures did not permit definite conclusion. - Statistically significant rectal cancer excess, and nearly statistically significant prostate cancer ex cesses In specific OEC ... may warrant further study. (6) UNIVERSITY OF MASSACHUSETTS MASTER THESIS - T. Liebllng (2/82) SCOPE: - 211 total cohort of employees during period 1976-1980. OBJECTIVES: - Identify any excess mortality associated with particular chemical exposures or work areas in the plant. CONCLUSIONS: - Significant excess of buccal/pharyngeal cancer observed in employees who may have been exposed to formaldehyde. UCC 085674