Document DGO1EXZ48K3gm1GyOxm2Nk9va

2171 MINUTES of the^Two-hundred eighty-fifth meeting of the Board of Directors of -he Chemical Manufacturers Association, Inc., held at the Hyatt Regency on Dapitol Hilli Washington, D. C., on Tuesday, Novemoer 3, 1981, at 1:30 p-m. Directors Secretary: General Counsel: Treasurer: By Invitation: Paul F. Oreffice, Chairman Louis Fernandez, Vice Chairman Richard C. Ashley William 8. Jackson Dexter F. Baker Raymond H. Marks Robert P. Barnett Dwight c. Minton Charles E. Brookes L. John Polite, Jr. Harry W. Buchanan William C. Roher Carlyle G. Caldwell Robert A. Roland Lester E. Coleman John P. Sachs Orell T. Collins George J. Sella, Jr. Robert S. Dudley William J. Simeral Richard E. Engebrecht Onn R. Smith Robert W. Gerwig Allan J. Tomlinson Arthur L. Goeschell Hugh B, Vanderbilt James 8. Henderson Edward A. Von Doersten Paul F. Hoffman Konrad M. Weis Edwin C. Holmer William G. West Richard J. Hughes Louis G. Zachary Ray R. Irani Bruce M. Barackman Edmund B. Frost Gary C. Herrman Jackson B. Browning, Union Carbide Corporation D. Christopher Cathcart, CMA Geraldine V. Cox, CMA John E. Dull, E. I. du Pont de Nemours & Company Myron T. Foveaux, CMA Robert B. Hill, CMA William C. Krumrei, The Procter & Gamble Company K. James O'Connor, Jr., CMA Victor H. Peterson, CMA Ernest S. Robson, SOCMA, Monsanto Company James N. Sites, CMA William M. Stover, CMA Glenn W. White, The Dow Chemical Company 1. The meeting was called to order by Chairman Oreffice. 2. APPROVAL OF SEPTEMBER 28-29, 1981 MINUTES Minutes of the September 28-29, 1981 meeting, as distributed, were approved. 3 - TREASURER'S REPORT Mr. Herrman's report is attached as Exhibit A. Additionally he advised that the latest financial statements concerning the four months ending September 30, 1981, CMA 012627 Fluorocarbons SPAC approved a limited advocacy role for the Fluorocarbons Program Panel so that the panel could make statements on science. The first was in response to the November 1979 NAS Report, "Stratospheric Ozone Depletion by Halocarbons: Chemistry and Transport." SPAC recommended that the panel continue its limited advocacy charter and appointed two members to explore appropriate means of coordinating the Alliance, the CMA Fluorocarbons Panel and the CMA Section 4 Testing Task Force of the Chemical Regulations Advisory Committee. 'atones SPAC endorsed the panel's plans to establish an early dialogue with EPA regarding the anticipated TSCA Section 4(a) rule. However, SPAC recommended that the panel's charter be amended to include epidemiologic studies and possible evaluation of the environmental effects of ketone. Phthalate Esters In sarly 1980 the phthalate Esters panel planned a material handling survey of the manufacturers, distributors and users of phthalates. However, since CMA is a trade association representing manufacturers, SPAC recommended that all action be tabled until the Society of the Plastics Industry could be contacted. In the meantime a study by the National Cancer Institute became available which for the first time raised health effects concerns for phthalate esters. In addition, based upon NCI's findings, EPA requested additional information on PMNs for phthalate esters. The panel was concerned that EPA had taken regulatory action on preliminary information and that EPA might come up with an unreasonable TSCA section 4(a) rule, SPAC recommended that the panel add advocacy to its charter and that they establish a dialogue with EPA on developing a voluntary test tandard. This was a valuable recommendation as can be seen by the ubsequenc accomplishments of this panel (section 7.4 of the attachment). Titanium Dioxide PAC recommended that in the absence of any significant findings in the Jtg-term inhalation study in progress at duPont, the panel consider disbanding. i Chloride ?inyl Chloride Panel hired an independent consultant to review the work naed by Industrial Bio-Test (IBT) under contract to CMA. This tudQt reconaafin(ied that CMA examine animal tissues still available from h, ^ The panel did not act upon this recommendation. However, they ^IBT for a refund of the $130,000 they had already paid under the The panel was waiting for financial resolution with IBT before k. 8 a final report to government agencies. SPAC recommended that - aot wait for resolution before submitting a final and report that upon t he consultants recommendation to do additional Shology, The Panel followed this recommendation. 3 CMA 012628 8.10 Ethylene Dichloride (EDC) The Ethylene Dichloride Program Panel was formed in Febru ary, 1975 to evaluate the adequacy of knowledge relating to EDC. The panel initiated a chronic inhalation, a metabolic, and a teratogenic study in experimental animals. The Panel decided to disband, pending the acceptance of all final reports on this research. This decision was reversed when it was learned that EPA was considering proposing a TSCA Section 8(a) rule. 8.11 Ethylene Oxide (EO) A study conducted at Bushy-Run labs showed Ethylene Oxide to be carcinogenic in rats. Industry was interested in gathering information on the safe handling of Ethylene Oxide which led to the formation of the Ethylene Oxide Industry Council on July 3o, 1981. The Council operates through an Executive Committee and four operating committees: Scientific, Regulatory, Finance and Membership, and Communications. The Council is developing Information regarding responsible industry programs to: 1) control exposure to ethylene oxidef 2) to develop relevant scientific, technological and economic data; and, 3) to cooperate with other national and international organ izations having similar objectives. The Council will present this information and data to any United States federal, state or municipal governmental body considering regulatory controls on ethylene oxide so as to assure that such standards, regulations or policies, are reasonable, scientifically sound, and economi cally and socially effective. The Council developed a response to the petition filed by the Public Citizen Health Research Group and the American Fed eration of State, County and Municipal Employees to lower the exposure standard for ethylene oxide. The petition asked that the eight hour TVA be lowered from 50 ppm to 1 ppm and that a short-term exposure level of 5 ppm be established. Representa tives of the Council met with OSHA officials on September 2 to discuss industry's concern regarding the petition. On September 29 OSHA denied the petition. 8.12 Fluorocarbons (FC) The Fluorocarbon Program was formally organized in th*> Spring of 1973 with essentially all of the Free World producer* of chlorofluorocarbons (CFCa) supporting the effort. The panel initial purpose was to determine the fate of CFCs in the atao* phere and the effects they may produce on plants or animal There was no suspicion of their effect on the stratosphere. With the publication of the Ozone Depletion Theory in J 1974 the Program was expanded and accelerated. To date,:?* $10,000,000 has been spent on this research. There is no ihtion that the participants Intend to curtail this effort in immediate future. CMA 012629 eral agencies. The panel also reviewed a draft final report oa a styrene pharmacokinetic study in mice. The latter study indi cated species differences with respect to acute styrene toxicity in rats and iJTCH. The panel presently is assessing how these differences .relate to man before proceeding further with a research program. The panel incorporated a Regulatory Task Group to address EPA's proposed regulations (NESHAP) for benzene emissions from ethyl benzene/styrene plants comments were submitted to EPA on June 1, 1981. 8.20 Titanium Dioxide (TD) In 1977, Du Pont initiated a review of the literature on titanium dioxide toxicity and concluded that further information was needed to answer possible questions which might be directed at titanium dioxide. The impact of the Toxic Substances Control Act also raised concern as to the adequacy of existing information. The panel has tentatively concluded that a historical mortality study is not justified at this time. The panel plans to terminate program activities if no new evidence of human health effects is reported as a result of the two year inhalation studies being conducted by Du Pont. 8.21 Trichloroethylene (TCE) The Trichloroethylene Program Panel was formed on Hay 12, 1975 in response to an NCI Memorandum of Alert. The panel's primary concern was a long-term inhalation study. A contract was signed in 1975 with Industrial BIO-TEST Laboratories (IBT) to conduct such a study. The testing performed by IBT resulted in a number of grave Inadequacies and a final report was not issued. Therefore, the CMA TCE Audit Task Group prepared an audit report. EPA's Cancer Assessment Group has asked the panel to provide validation of chamber concentrations for the first 12 to 15 months of the IBT study. The panel is monitoring the progress of the NCI bioassay on TCE which involves several strains of mice and rats. Although the panel contemplated an epidemiological study, SOCMA determined that a study population for an epidemiologic investigation would be too small to yield statistically signif icant results. Therefore, such a study was not conducted. 8.22 Vinyl Chloride (VC) Since 1972, the Program Panel has supported activities related to the accumulation and assessment of health and safety data of vinyl chloride monomer. 13 CMA 012630 After funding several animal studies, the emphasis on research shifted from toxicological investigations to the early diagnosis and clinical management of vinyl chloride-related injuries. The panel is al3o funding an update of a vinyl chloride epidemiology study of 10,000 workers. The panel has maintained a close liaison with SPI and several European-based companies. The present interest in polyvinyl chloride (PVC) dust control limits in the UK is being closely followed. Several months ago OSHA requested information on PVC dust; however, no notice has been published or other action taken. 8.23 Vinylldene Chloride (VDC) The Vinylldene Chloride Program Panel was formed in May 15, 1974 to investigate the potential toxicologic effects and pharma cokinetics of inhaled and Ingested VDC in laboratory animals. Dow Chemical, which was planning research on VDC toxicology, agreed to convert its program into an industry-wide effort. The Two-Year Inhalation Toxicity and Oncogenicity Study of Vinylldene Chloride in Rats is stil In progress. The Work Practices Task Group of the panel prepared a Health and Safety Work Practices Guideline for Vinylldene Chloride to minimize exposure to vuu. The guidelines Wre send To the Director of NIOSH and the Project Manager for Criteria Documents at SRI. They received no ocher distribution. The panel is preparing to respond to a Health Risk Assess ment Criteria document on VDC under preparation by the EPA Cri teria and Health Assessment Group. OSHA does not have a standard for VDC and EPA is unlikely to require any further toxicity testing on VDC under TSCA Section 4. The pharmacokinetics and metabolism research show a species sensitivity of Mouse>Rat>Man. The total data bank indicates oncogenicity is not observed without recurrent tissue damage and without a cytotoxic dose; a tumorigenic response in man would be an improbable event. 8.24 Zinc Dialkyl Dlthiophosphates (ZDDP) The ZDDP Program Panel was chartered in November 1980 to conduct research on this class of oil additives. As a first step, gonadal toxicity studies of three ZDDP compounds were initiated in Immature and mature rats and rabbits. Obvious species differences were observed between rabbits and rats with respect to ZDDP toxicity. Consequently, the panel proposes to conduct a comparative in vivo pharmacokinetic study 19 CMA 012631 TABLE 1 BIOMEDICAL"AND ENVIRONMENTAL SPECIAL PROGRAMS BUDGET SUMMARY4 PROGRAM ~ RESEARCH AND ADMINISTRATIVE ADVOCACY COMMITMENT EXPENSES TOTAL Acrylonitrile $ 728,484 $ 79,172 $807,656 Allyl Chloride 309,500 17,186 326,686 Arsenic 10,000 8,600 18,600 Benzene 3,048,684 112,262 3,160,946 Bucylated Hyd roxytoluene 21,944 29,467 51,411 Chlorobenzenes 370,722 37,952 408,674 Epichlorohydrin 315,032 27,432 342,464 Epoxy Resins Ethylene Dibromide Ethylene Dichloride Ethylene Oxide Glycol Ethers Ketones -010,039 288,100 -0313,000 208,880 15,059 43,032 64,449 15,518 15,232 28,977 15,059 53,071 352,549 . 15,518 328,232 237,857 Phosgene 217,512 85,728 303,240 Phthalate Esters 186,585 132,628 319,213 Polychlorinated Biphenyls 100,434 18,869 119,303 Rubber Additives Styrene Titanium Dioxide 30,725 708,218 30,725 17,730 66,545 23,969 48,455 774,763 54,694 Trichloroethylene Vinyl Chloride Vinylidene Chloride Zinc Dialkyl Dithiophosphates Subtotal Rluo rocarbons 490,506 1,326,562 729,482 79,857 9,524,991 9,216,650 89,738 119,701 57,440 580,244 1,446,263 786,922 12,207 1,118,893 569,753 92,064 10,643,884 9,786,403 TOTAL $18,741,641 $1,688,646 $20,430,287 Fluorocarbons program from start thru May 30, 1981. All other programs start to Co September 25, 1981. CMA 012632 ro m u? cn oH U shared Figure 1 - BlomeiHcal anA Environmental Specie! Progrons Division IMBER 1. 2. 3. 4. 5. PROGRAM NAPE Acrylonitrile Allyl Chloride Arsenic Benzene Butyl^ted^Hy droxytoluene 6. Chlorobenzenes 7. Eplchlorohy drIn 8. Epoxy Resins 9. Ethylene Dlbromlde 10. Ethylene Diehlorlde 11. Ethylene Oxide 12. Fluorocarbons 13. Glycol Ethers 14. Ketones 15. Phosgene 16. Phthalate Esters 17. Polychlorinated Biphenols 18. Rubber Additives 19. Styrene 1 li j i 20. Titanium Dloxl de 21. Trlchloroethylene 22. Vinyl Chloride 23. Vlnylldene Chloride 24. Zinc 01 alkyl D1thiopnosphates LIST OF SPECIAL PROGRAMS PROGRAM TYPE START DATE Research Research 06/20/74 08/19/75 Research and Advocacy 01/29/81 Research and Advocacy 02/08/77 Research and Advocacy Research Research Research and Advocacy Research Research Research and Advocacy Research and Advocacy Research and Advocacy Research and Advocacy Research Research and Advocacy Advocacy Research and Advocacy Research and Advocacy Research Research Research and Advocacy Research 09/19/77 12/16/74 08/19/75 01/18/77 03/22/79 12/17/74 04/16/81 04/09/73 06/26/80 01/23/80 05/18/72 02/24/72 02/11/81 09/10/79 10/24/74 06/13/77 05/12/75 11/16/71 05/15/74 Research and Advocacy 10/02/80 COMPLETION OATE | 08/31/80 Appendix B Appendix C COMPANIES PARTICIPATING IN SPECIAL PROGRAMS ABBOTT LABS Ethylene Oxide AIR PRODUCTS Vlny'l Chloride AK2Q CHEMIE BV Fluorocarbons ALLIED CORPORATION Fluorocarbons, Ketones, Phthalate Esters, Phosgene AMAX LEAD & ZINC, INC. Arsenic AMERICAN CYANAMID Acrylonitrile, Phthalate Esters, Rubber Additives AMERICAN HOECHST Styrene AMOCO Benzene, Styrene, Zinc Dialkyl Dithiophosphates ANACONDA COPPER COMPANY Arsenic ARCO CHEMICAL Benzene, Phthalate Esters, Polychlorinated Biphenyls ARCO/POLYMERS Styrene ASAHI-DOW LIMITED Vinylidene Chloride ASAHI GLASS CO., LTD. fTuorocarbons,- Vinylidene Chloride ASARCO INC. Arsenic ASHLAND CHEMICAL Benzene ASSOCIATED OCTEL COMPANY fitnyiene Dibromide CMA 012635 C-2 AUSTRALIAN FLUORINE CHEMICALS PARTY, LTD. Fluorocarbons BASF WYANADOTTE Ethylene Di-ehloride, Ethylene Oxide, Phosgene, Phthalate Esters. BECTON DICKINSON Ethylene Oxide BETHLEHEM STEEL Benzene BORDEN CHEMICAL Ethylene Dichloride, Phthalate Esters, Vinyl Chloride BORG-WARNER CHEMICALS Acrylonitrile, Styrene BRISTOL LABS Ethylene Oxide C-I-L, INC. Trichloroethylene CELANESE PLASTICS SPECIALTIES CO. Epoxy Resins, Ethylene Oxide CERTAIN-TEED Vinyl Chloride CHESEBROUGH PONDS Ethylene Oxide CHEVRON Phthalate Esters, Zinc Dialkyl Dithiophosphates CIBA-GEIGY Epoxy Resins CONOCO CHEMICALS Ethylene Dichloride, Ethylene Oxide, Phthalate Esters, Vinyl Chloride COSDEN OIL Benzene, Styrene CRESCENT MANUFACTURING CO Ethylene Oxide DAIKIN KOGYO CO. LTD, Fluorocarbons CM& 012636 C-3 DART INDUSTRIES Butylated Hydroxytoluene DIAMOND SHAMRfrCK Arsenic, Ethylene Dichloride, Polychlorinated Biphenyls, Phthalate Esters, Trichloroethylene, Vinyl Chloride DOW CHEMICAL Acrylonitrile, Allyl Chloride, Benzene, Chlorobenzenes, Epoxy Resins, Ethylene Dibromide, Ethylene Dichloride, Ethylene Oxide, Glycol Ethers, Ketones, Styrene, Trichloroethylene, Vinyl Chloride, Vinylidene Chloride E. I. DO PONT DE NEMOURS & CO. Acrylonitrile, Benzene, Ethylene Dichloride, Fluorocarbons, Phosgene, Phthalate Esters, Polychlorinated Biphenyls, Titanium Dioxide, Vinylidene Chloride DU PONT CANADA INC. Fluorocarbons ELCO CORPORATION Zinc Dialkyl Dithiophosphates EL PASO PRODUCTS COMPANY Styrene EASTMAN KODAK Polychlorinated Biphenyls ESSEX CHEMICAL (RACON) Fluorocarbons ETHYL CORPORATION Allyl Chloride, Ethylene Dibromide, Ethylene Dichloride, Phthalate Esters, Trichloroethylene, Vinyl Chloride, Zinc Dialkyl Dithiophosphates EXXON Benzene, Ketones, Polychlorinated Biphenyls, Phthalate Esters, Vinyl Chloride, Zinc Dialkyl Dithiophosphates FOXMATIC CORP Ethylene Oxide GENERAL ELECTRIC Phosgene, Phthalate Esters, Polychlorinated Biphenyls GENERAL TIRE & RUBBER phthalate Esters, Vinyl Chloride CMA 012637 C-4 BFGOODRICH Allyl Chloride, Ethylene Dichloride, Rubber Additives, Vinyl Chloride,-Vinylidene Chloride GOODYEAR TIRE & RUBBER Rubber Additives, Vinyl Chloride W. R. GRACE Vinyl Chloride, Vinylidene Chloride GREAT AMERICAN CHEMICAL vinyl Chloride GREAT LAKES Ethylene Dibromide GULF CHEMICAL CO. Acrylonitrile, Benzene, Ethylene Dichloride, Styrene, Vinyl Chloride GULF & WESTERN Titanium Dioxide HALCON Ethylene Oxide HOECHST AG/AMERICAN HOECHST Fluorocarbons ' HOOKER CHEMICAL Polychlorinated Biphenyls, Trichloroethylene, Vinyl Chloride ICI AMERICAS Ethylene Dichloride, Glycol Ethers, Vinyl Chloride IMPERIAL CHEMICAL INDUSTRIES PLC Fluorocarbons, Trichloroethylene INMONT CORPORATION Phthalate Esters ISC CHEMICALS LTD Fluorocarbons JAPAN FLON GAS ASSOC. Fluorocarbons JOHNSON & JOHNSON Ethylene Oxide CMA 012638 C-5 KAISER ALUMINUM AND CHEMICAL CORP FluorcarbonTpPolychlorinated Biphenyls KALI CHEMIE ACT Fluorocarbons KENDALL CO Ethylene Oxide KEYSOR-CENTURY Vinyl Chloride KOPPERS COMPANY Arsenic, Benzene, Butylated Hydroxytoluene, Phthalate Esters KUREHA CHEMICAL INDUSTRY Vinylidene Chloride LUBRIZOL Zinc Dialkyl Dithiophosphates MALLINCKRODT INC Ethylene Oxide MICRO BIOTROL Ethylene Oxide MITSUI FLUOROCHEMICALS LTD Fluorocarbons MOBAY CHEMICAL Phosgene, Rubber Additives MOBIL OIL CORPORATION Benzene, Phthalate Esters MONSANTO COMPANY Acrylonitrile, Benzene, Chlorobenzenes, Ketones, Polychlorinated Biphenyls, Phthalate Esters, Rubber Additives, Styrene, Vinyl Chloride, Vinylidene Chloride MONTEDISON SPA Fluorocarbons, Phosgene MONTROSE CHEMICAL CORP OF CA Chlorobenzenes MORTON CHEMICAL Vinylidene Chloride CMA 012639 NALCO CHEMICAL COMPANY Ethylene Oxide C-6 ML INDUSTRIES TitaniunToIoxide QLIN CORPORATION Glycol Ethers, Polychlorinated Biphenyls, Phosgene, Vinylidene Chloride OSMOSE WOOD PRESERVING COMPANY Arsenic ' PANTASOTE Phthalate Esters PENNWALT Arsenic, Fluorocarbons, Rubber Additives PHILLIPS PETROLEUM COMPANY Benzene PPG INDUSTRIES Chlorobenzenes, Ethylene Dibromide, Ethylene Dichloride, Ethylene Oxide, Glycol Ethers, Polychlorinated Biphenyls, Phosgene, Trichloroethylene, Vinyl Chloride, Vinylidene Chloride POLYSAR LIMITED Benzene PRODUITS CHIMIQUES UGINE KUHLMANN Fluorocarbons REICHHOLD CHEMICALS Epoxy Resins ROHM & HAAS Vinylidene Dichloride RUBICON Phosgene SALSBURY LABS Arsenic SCM CORPORATION Titanium Dioxide SHELL CHEMICAL COMPANY Allyl Chloride, Benzene, Butylated Hydroxytoluene, Epoxy Resins, Ethylene Dichloride, Ethylene Oxide, Glycol Ethers, Ketones, Phthalate Esters, Vinyl Chloride, Styrene, Zinc Dialkyl Dithiophosphates, SHERWIN WILLIAMS Butylated Hydroxytoluene CMA, 012640 C-7 SHERWOOD MED-ICAD Ethylene Oxide SHOWA DENKO RK Fluorocarbons STANDARD CHLORINE CHEMICAL CO "Chlorobenzenes ` STANDARD OIL (OHIO), Acrylonitrile, Benzene STANGE COMPANY Ethylene Oxide STAUFFER CHEMICAL Ethylene Dichloride, Phosgene, Phthalate Esters, Polychlorinated Biphenyls, vinyl Chloride STEPEN CHEMICAL Phthalate Esters SUN PETROLEUM PRODUCTS Styrene ~ SUNSHINE MINING CO Arsenic TECKNOR-APEX Phthalate Esters TENNESSEE EASTMAN Acrylonitrile, Glycol Ethers, Ketones, Phthalate Esters, Vinylidene Chloride TENNECO CHEMICALS Vinyl Chloride TEXACO INC Benzene, Ethylene Oxide, Glycol Ethers, Zinc Dialkyl Dithiophosphates, TIOXIDE CANADA, LTD Titanium Dioxide TOMS RIVER Phosgene TRAVENOL LABS Ethylene Oxide UNION CARBIDE Benzene, Ethylene Dichloride, Ethylene Oxide, Glycol Ethers, Ketones, Polychlorinated Biphenyls, Phosgene, Phthalate Esters, Styrene, Vinyl Chloride CMA 012641 c-a UNION OIL OF CA Vinylidene Chloride UN I ROYAL, INC-. Acrylonitri Chloride Butylated Hydroxytoluene, Rubber Additives, Vinyl USS CHEMICALS Benzene, Phthalate Esters, Styrene UPJOHN COMPANY Phosgene VULCAN MATERIALS Ethylene Dichloride, Polychlorinated Biphenyls WITCO CHEMICALS Phthalate Esters WARREN CHEMICAL CO Ethylene Oxide 9/25/81 CMA 012642 8 Butyl ated _Hydroxytol uene (BHT) The j;oi nt FAO/WHO- Expert Committee on Food Additives re cently extended the temporary average daily intake (ADI) for BHT, pending receipt of additional testing data. Chiorobenzenes EPA and the ch1orobenzenes producers have agreed on a decision-tree approach to the testing of chiorobenzenes in the voluntary industry test program. The Toxicology Research Group has recommended that Dr. Gary Williams of the American Health Foundation perform the cell transformation assays and EPA is in agreement with this recommendation. Requests for proposals to conduct a two-generation reproduction study on monochloro benzene were sent to five contract laboratories. Ethylene Dibromide (EDB) The Internationa1 Brotherhood of Teamsters urged in a September 2, 1981, petition that the Occupational Safety and Health Administration (OSHA) issue an emergency temporary standard (ETS) reducing the exposure limit for the fumigant EDB. The Teamsters' petition claims that "three major studiesshow ED8 to be a potent carcinogen at levels far below those allowed under the present OSHA standard. OSHA has been asked to write an ETS. OSHA has no definitive plan of action until it has obtained more data. Information from the panel will be considered. Dr. L. Vernon White of Great Lakes Chemical and Mr. Roger Mangham of Ethyl Corporation will attend an OSHA meeting on EDB on October 13 as industry representatives. Ethylene Oichloride The Ethylene Dichloride Program Panel is endeavoring to clarify several questions relating to the final report of the chronic inhalation study conducted for the panel by Drs. Maltoni and Spreafico. Ethylene Oxide Membership of the newly formed Ethylene Oxide Industry Council includes 28 companies and associations. The Scientific and Regulatory Committees have formed several task forces that are in the process of developing programs. Budgets and proposals are to be submitted to the EOIC Executive Committee by November 1. On September 28, OSHA denied a petition of the the Public Citizen Health Research Group and the American Federation of State, County and Municipal Employees to issue an emergency temporary standard. Also OSHA stated that an advance notice of proposed rulemaking (ANPR) woul-d be issued. Included in the CMA 012643 At prese.it, Panel participants include: The Dow Chemical Company Great Lakes Chemical Company, PPG Industries, E.I. du Pont de Nemours $ Co., Inc. and Ethyl Corporation. Ethylene Dichloride The Ethylene Dichloride Panel is reviewing a response from Montedison concerning several previously unanswered questions regarding the final report by Professor Maltoni. Ethylene Oxide (EO) The Ethylene Oxide industry Council (SOIC) met in early December to review and approve the budget and proposed program for 1982. Activities of the EOIC are expected to include : Response to an anticipated OSHA Advance Notice of proposed Rulemaking,- Interaction with EPA concerning a Toxic Substances Control Act Section 4(a) test rule on EO; A human health risk assessment of exposure to EO; An economic regulatory impact study,- Development of an industrial hygiene survey to assess workplace practices; A scientific program that will include a pharmaco kinetic study, reproduction study or epidemiology s tudy ; Equivalency testing of monitoring methods and analy sis used for measuring EO in the workplace; Development of a training program for EO workers,- and Sponsorship of a cytogenetics workshop. Fluorocarbons Dr. Donald R. Strobach of Du Pont addressed the Technical Breakfast on December 10, 1981. The Fluorocarbon Program Panel (ppp) is making rapid progress toward jointly funding approximately $500,000 of CMA 012644