Document DGL62n20aVdoZw0DGn8jvbDN

Ootober 11, 1965 Mr. Merle Hughes Chemistry Supervisor Chevrolet Forge Plant Tonswanda. Mew York Dear Mr. Hughes 1 O-l- Ik;--tv CU'i<jO Maok Niohols of our Cleveland office has asked me to forward toxicity and safe handling information for Animal toxicity studies with this product 1 the oral lethal dose (UVq) to rats is 10, ^00 milligrams per kilogram. The lethal dose when the material was applied undiluted to the unbroken skin of rabbits is approximately 125O milligrams per kilogram. We oonclude from the above that accidental ingestion on the part of humans is not a particular hasard in view of the high oral lethal dose in rats. Similarly, single massive skin exposures should not be immediately hazardous. The lethal dose obtained in skin penetration studies is suoh, however, that prolonged and repeated skin eonteot should be avoided because of possible systemio effeots. In addition, prolonged and repeated skin contact may lead to skin irritation. We also feel that vapor inhalation should be avoided when the fluid is heated to elevated temperatures. Such exposure l again relates to prolonged or repeated exposure. rather - _. - ' than short-term massive or acute exposures.j lh the oase of 4 'V. rtHe~lltter. workmennwouia~not voluntarily"txpose themselves | i tb'doneentratlons that are hasardous because of irritation of j ' the respiratory tract. The use of Pydraul A-20Q in industrial hydraulic fluid appli-"~ cations should not present toxicity hazards during the trans fer of the fluid from original containers to the hydraulic system. Obviously when the fluid le within the hydraulic system, there should be no exposure end consequently, no hasard. In the event of rupture of hydraulic lines and subsequent splashing or spraying of the fluid on the heated DSW 018822 STLCOPCB4005366 Hr, Merit Hughe* October 11, 1965 Page 2 surface*, vapor* of the fluid and poaalble decomposition products (depending on the temperature of the heated surface) may be irritating if inhaled to the degree that workmen will not voluntarily expose themselves to toxlo concentrations. No hazardous exposure should result during the interval required to shut down the system and obtain suitable respiratory protective devices during repairs to the system. We would not anticipate any greater hazards during routine maintenance of a system containing Pydraul A-200 than would be present if the system contained a phosphate base fluid. It would appear to be good practice to wipe dry any equipment before doing any welding on surfaces which might be "wetted" with or have a film of either type fluid on them, _ \ ' If the above information does not/ answer your specific questions pleach 1st ass know directly ^or through Mr./ Nichols. Very truly yours, n e <_ Bluer p* Wheeler Manager, Environmental Health Medical Department fiPtfiaJb cot II. Oaaton, Safety Supervisor, Chevrolet Dr. J, J, Srandl, Medical Division, Chevrolet J. J. NsMell, Plant Engineer, Chevrolet Prank DlQiacoeao, Purehasing Dept,, Chevrolet Maek Nichole - Monsanto, Cleveland - 0,L. &.M. Ci(,o DSW 018823 STLCOPCB4005367