Document DDnnMGJwg2ELk705oK2bnvZQo

- EXHIBIT kiinsteic 0 'V jg Monsanto wmhi* CtmfiMf too N. tUlMK II. I fail. Miiiiwi 13186 INMI dlC II4I000 July 18, 1975 i9 Dr. J.C. Galandrs, Industrial BIO-TEST Laboratories 1810 Frontage Id. ,, ,, Horthbrook, 111. 6C062 re: ARCGLOR 2-year tot Feeding Studies Dar Jot i * The attached table summarises a comparison of tht 3 revised AROCLOH reports (1242, 1254, 1250). i ' In 2 instances, the previous conclusion of ''lightly tusorigenie" T.' * vis changed to "does not appear to be carcinogenic". The latter 1 phrase is preferable, Kay m request that the AROCLOH 1254 report be acended to *ay "does not appear to be carcinogenic''. The number of hepatomas reported for AROCLORS i860 and 1242 have been interchanged. This appears to have arisen from con fusion regarding the nuabering of the animals. The original reports show tumors lr. anlsala with numbers in the 100-300 ring# for AROCLOH 1260 and in the 500 to 800 range for AROCLOH 1242. This leads a to conclude that tha nuabering scheat shown in the second set of reports Is correct. With AROCLOH 1254 confusion is conpounded. The original report showed turners in anlsals with numbers In the units to teens, but the revised report shows animal numbers ranging frea 4o to 1000, Can this be straightened out? . 1 was unable to reconcile tht differences in tha animal nuobers between tha first supplemental report and the original reports, 1 had inquired as to the changes in the numbers. As I recall, 2 was told that the sections had been renuaoered when the new slides were made and that a kty relating to the sets of numbers . 100737 Enni 271 RECEIVED v3 T HARTOLDMON0015618 f Dr- J.C. Calandra July 18, 1975' P&8 - 2 - - c - - would be supplied, This has not been done, it say not be necessary ter AROCtOSS 1260 and 1243, but AROCLOR 1254 reaains unresolvad. Insofar as I can see, the remainder of the reports appear acceptable. Kindest personal regards, Sinerely, George J. Levinskas, PhD Kgr., Environeental Asseescent and Toxicology /bkp at t ccj Dr. George Roush, Jr., M.D. B/P'd |.;nni ?.72 lOOTJn 'xi-stmta * aane s kc^s tfr.-n es, bi eu HARTOLDMON0015619 r J f V" .-^4 Supplemental Report A30CLOR 1260 conclusion ' slightly tuaorigenie hepatoaM 3 range of test animal nos; _ p. 9 cOO to 800 p; io 1000 series p* n p. 12 70 to 100 goo to 6oo p. 13 00 to 700 p. 14 700 series flupplesental Renort #g_iJCg dellviwH) dots not appear carcinogenic 100 to 300 800 to 900 10 to So So to 200 200 to 300 200 to 300 >4 AROCIOR 12g4 conclusion hepatoma slightly tusorigenie 6 slightly tusorigsnic AROCLOR 1242 conclusion Slightly tumorigenie idoes not appear carcinogenic hepatoma 7 range of teat animal nos. aa In report #2 i for AROCLOR 1260 ABOCLOR 128b 8/S'd RIM 273 10073:) , xi'strnta * acra 3 oobfs st- . t i es, ex oj HARTOLDMONO015620