Document DDZwmgvDRNnY0nwqKkk0J8w5M

FILE NAME Industrial Hygiene Foundation IHF DATE 1942 Apr DOC IHF032 DOCUMENT DESCRIPTION Abstracts Industrial Hygiene Digest -10 | | April 1942 fluorides several departures from standard foundry practice which introduce materials not usually encountered in foundries Thus in addition to the usual air contamin- ants characteristic of foundries there may be water soluble fluoric acid sulphur dioxide chromic acid carbon tetrafclh uolrio mdaergsniehsdyiduermo- oxido and magnesium metul -- and this list will probably grow as time on Data are presented as to concentrations of fluorides found in the goes several operations which may give rise to these vicinity of | compounds in air In addition . concentrations of MgO and S02 from pouring and salting out are reported Diffi- culties experienced as a result of these exposures and suggestions for overcoming them are presonted _ prin- 364 The Netabolism of Fluorides W. Machle and E.J. Largent Prosented at Amer Ind Hyg Assoc Convention Cincinnati C. April 1942 Mottled enamel industrial fluorosis Darmous Guddur and fluorine cachexia are clinical abnormalities caused by the absorption of excessive amounts of fluoride Moreover acute fatal poisoning has resulted from the ingestion of fluorides The existence of these problems of public health and industry has occasioned in- vestigation of the behavior of fluoride in the bodies of human experimental sub- jects Balance experiments have established levels of intake and output of ' fluoride with the subject on a normal diet The urine was found to be the cipal route of excretion There was increased absorption and retention when fluoride was added to the diet in different amounts up to 25 times the normal = intake Within rather wide limits a relatively constant proportion of the ex- cess fluoride was stored in the body Absorption of fluoride in quantities to 1 mgm per diem was not associated with up storage but amounts greater then 2 mgm per dien resulted in storage The quantities stored were not released and excreted after the intake was reduced to normal levels The absorption of fluoride is greatly affected by the aqueous solubility of the fluoride salt ingested Very large amounts of fluorida may be stored in the bones without the appearance of roentgenologic changes although the bones are abnormal : oe Lg _ i aa i : Pe sCiw@si ] | | 365 Silicon and Silicon Helogens 857 March 7 1942 Queries & Minor Notes J. Am Med Assoc 118 In reply to a query concerning industrial poisoning by silicon gas several possible forms of exposure are discussed borne suspensions of the element silicon might be construed as gaseous in the fume liberated on electric furnace treatment The fine particles of such fumes collect as long cobweb stream- ers in flues rafters etc. has been shown by animal experimentation that this form is inert and incapable of producing tissue changes except phagocytosis The same was found true of coarser particles 1 to 3 microns in diameter On the other hand some of the gaseous compounds of silicon are injurious Silicon tetrafluoride is a colorless irritating gas The tetrachloride has a suffocat- ing odor and is used in the preparation of smoke screens Several other halogen compounds are known Of the organic silicates that might be inhaled as vapors othyl silicate has been found to be highly toxic on injection into animals : = _ i ty 6366 f Bronchiogenic Carcinoma in Association with Pulmonary Asbestosis Report of fl Two Cases H.H.Holleb and A.Angrist Am.J.Pathology 18 123 125January Two cases are reported in which men between 40 and 50 were found to have both asbestosis and a primary carcinoma of the lungs A table listing 10 reported cases collected from the literature in which both diseases occurred is pre- sented The authors conclude that the date from 2 cases with some reports in the literature in doubt are insufficient for a statistical evaluation and that caution should be used in ascribing carcinoma to asbestosis In one case the carcinoma was in a region least affected by asbestosis but where carcinomas often occun DEPOSITION DEPOSITION EXHIBIT DEPOSITION DEPOSITION EXHIBIT DEPOSITION A - Castlem 6 Castlem # Castlem Da Da . : hee Ueno Be Dek an