Document DDB2La7Jp3NN8jGOk1009eeGo
Plausibility
Mesotheliomas develop in the pleura, peritoneum and other mesothelial cells (Mutsaers, 2004).
Chrysotile is a cause of cancer in the lung and chrysotile migrates to the mesothelial linings of the body (Suzuki & Kolynema, 1991) (Kolyema & Suzuki, 1991) (Sebastien, et al, 1980).
Studies indicate that chrysotile penetrates individual cells, enters the nucleus and induces abnormal chromosome formations in dividing cells (Malami, et al, 1990)
Some of the abnormalites include the deletion of the P53 gene growth (Leversse, et al, 1997)