Document D1G5nD8GEvx079b2OwgqD25Q

DownloadRandom document
ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE Identity:MixturecontainingPerfluorooctanesulfonatweh,ich may alsobe referredtoas PFOS, FC-95, or as a component ofFC-206A. (1Octanesulfoniaccid)(CAS # 2795-39-3). Remarks: The 3M productionlotnumber was cc 785-22. The testsample isFC-206A. Currentinformationindicatesitisa mixtureof 0.92% PFOS, 18.75% diethyleneglycolbutylether,75.44% water,1.83% Hydroxy foamer, 1.75% sodium octylsulfate1,.2% poloxyethylenemonooctylphenylether, 0.06% sodium laurylsulfatea,nd 0.05% benzotdazole. The followingsummary applies toa mixture with incompletely characterizedconcentrations of impudties. Data may not accurately reflectthe toxicityof the fluorochemkal component of the testsample. METHOD: Method: Not given. Type: Acute continuousflow GLP: No Year completed: 1979 Species: Pimephalespromelas Supplier:Commerical supplieirnBrady,NE Analyticalmonitoring: Temperature,pH, and DO. Exposure period:96-hours Statisticamlethods: LCm valuecalculateudsingprobitcomputer program. Test fishage: Juveniles Length and weight: Average length 41 mm Loading: 0.64g/L Average weight 0.64g (wet) Pretreatment:None Test conditions: Dilutionwater: Carbon-filterweedllwater Dilutionwater chemistry: Hardness: Alkalinity: Conductivity: 236 rng/Las CaC03 221 mg/L as CaC03 430 pmhos/cm Lighting:Notgiven. Stock and testsolutionpreparation:A primarystocksolutiownas prepared at2lO,OOOmg/L. General dilutiofnactorof70,equivalentto3,000 mg/L. The primarystockwas proportionalldyilutedwithdilutiownaterforthe additionacloncentrabons:dilutiosneries100%, 60%, 40%, 20%, 10%, and 0%. Flow-througrhate:Approximate4l.y5volumeadditioonfstestsolution every 24 hours. Concentrations dosing rate:Contnuous Stabilityof the testchemical solutions: Not noted. Exposure vessels: Glass tanks (36x2lx24 cm) containing16 L oftest solution. Number of replicates:1 Number of fish per replicate:16 Number of concentrations: fiveplusa blank control Water chemistry during the study: pH range (0-96hours): 7.9 - 8.0 (controelxposure) 7.6- 8.0(3000 mg/L exposure) Temperature range (0-96hours): 18 -21 *C Dissolved oxygen range (0-96hours): 7.0- 9.3 mg/L (controelxposure) 4.5- 9.3mg/L (3000 mg/L exposure) RESULTS Nominal concentrations: Blank control3,00, 600, 1200, 1800, and 3000 mg/L Element values: 96-hour LC5o = >3000 mg/L Element valuesbased on nominalconcentrations Remarks: Tesbng was conducted on a mixtureas describedintheTest Substance Remarks field.The valuesreportedapplytothatmixtureand not the fluorochemicalproportionalone. CONCLUSIONS The testsample 96-hour LC50forfatheadminnow was determined tobe >3000 mg/L,the highestconcentrationtested.Thisconcentrationcaused a 12.5% mortality. Submitter: 3M Company, EnvironmentalLaboratory,P.O. Box 33331, St. Paul,Minnesota,55133 DATA QUALITY ReliabilityK:limischranking3. Testinglacksrecordofmethodology used. There isa lackofcharactedzabonofthetestsample and thestudylacks analyticaclonfirmatioonfthe amount offluorochemicalproportioninthe solution. REFERENCES Thisstudywas conducted by the3M Company, EnvironmentalLaboratory, St.Paul,MN, Lab Request number 4970S, 1979. OTHER Last changed: 6/26/00 RUVIKOMTAL LABMTIORY WnC TOXICIrtDATA SHM L-JE4170 S Type Test- Obte" Tested C)roA ec- T03t Or#anisAl&T@-@AfAJI- )Idjg ,Jj. I Date R*cld.ro Avg, wt. gnm AV 0 size-4-jNLoA-oramisPmOTdose Batch No.-S Ir, Test Solution Vol=* IfoLiton/All-Moss Tmk Tmk Di@siau-. 3u2i co and 24 co deep Time Start*d !L.-OC, Date sta"04 --7 Date COWI*tod 2t Dilution Water Carbon-ftits we Investigator (Full signatim) _(Tom. LCSO (tS% C=fi&MCS CAA. 010UsitS) pH c) yn-17t. Total 34 Too* cone. ..ft. -pa/i AAdmdmeadt Total 0000 Total boos ?cow 00, Total 0 @-pow-@ - ft. 0*" 'OWN ift W.Boad i* No IL Control 0 -7.9 C) -7.9 7 T 0 (5 300 4.eab 0 7.'9 V.ID- 0 ? C) 0 2 6I)o (?It,lo0o 7. C, 9.0 7 3 t,to i> 41 1900 S?,10 0 -2.1 7.7 0 '7 0 AS-9 0 voi) 419,000 7 7-@7S.r, -76 4. Test Temp. *c. SiznatLwo u TE4-& 4 rdpl e._ -- . z hc. @%4 I I No%,% - -7- 'z -7- Co@nts:-T@,t- rf.,j--4-@&"k" '7 21 fi-\,% WLYT V,'# t@@tt-,L e-,Ypol,,ft *i\.,A.C-,I@,.\.&A Effects ottl@r14agn-i@@ality ic Init. conc. ..!&/I Symptoms or Reactions !4 24-Hr. = Total No. Affected 48 Hr. 72-fir.--,- Controlt %-Hr. .Signature Comwnts: Date IT 7p r CL 4 41) --C L 4L -)'Y.57. _V A2 r\ fA C@rv Y L) Co. Ole. A(il 4D c> ev c> 774@ L& A- Y313 FORM -@A14PLE )ESe-ItIPTIGA tAlkSO9 F IL'TIEIKU WELL B-IOASSAY RMM 7- 18-'7A 78 M-2#-72 It-0 - 47t Ic . . . ..................... t46@ ATRACIVIENI tv T q 7.7 q%o @ul 0 117' _jL_ -I.L qlo 41 4r 41 - -g- ill o 2.31 alr7 a'$& S&L 4061, 1 40ft 0a -LIL- (O.I_-CI qOr 2%0 _o aft 1%3