Document Bvy37DGVXJgXLx0x5N17a98xm

A R 2 2 6 -2 0 6 8 VW SAFETY, HEALTH AND ENVIRONMENTAL C8 AMMONIUM PERFLUORO-OCTANOATE FC--1 43 ANIONIC FLUOROCHEMICAL SURFACTANT MGF by 3M COMPANY v -5 o DuPONT AEL: 0 .01 m g /M 3 (0 .5 6 ppb, 8 hr TWA) o IRRITANT via INHALATION. SKIN o r EYE CONTACT o MODERATELY TOXIC (ORAL) o ACUTE OVER-EXPOSURE: LIVER INJURY o CHRONIC EXPOSURE - - LIVER ENLARGEMENT - ELEVATED BLOOD FLUORINE LEVELS o NO KNOWN MEDICAL PROBLEMS FROM C8 (3 5 y e a rs ) . o C8 IS NOT: - A TERATOGEN - EMBRYOTOXIN - MUTAGEN RJZ030291 DAS 10/*, 0 EID 112755 v*>e**w^mvum^fftann-je. Il f 2./I7 SflfAT IS fc tl o ammonium perfluorooctanoate - qf3 <cf2 )6 C 0 FC-143 q FC-118 (20% SOLUTION) 0 CAS NO. 3825-26-1 | 0" nh4 WHAT TS TT USED FOR? o DISPERSING AGENT - POLYMERIZATION (USED SINCE LATE 1950'S 0 OR EARLY 1960 5 V. 0 TEFLON* POLYMERS - ALL POLYMERIZATION BATCHES o TEFLON* COPOLYMERS - FEP POLYMERIZATION 0 VITON* KALREZ* FLUOROELASTOMERS ) EID 112756 C-8 CONTROL LEVELS TIV -- 0 . 1 MG/M3 t LIVER EFFECTS AEL 0.01 MG/3 LIVER EFFECTS c a n c e r STUDY RESULTS bioperbistence CEG - 0.0003 MG/H3 (CEGW - 1 FFB) PEMDHG FBI. 4 AEL '-Tu. *gtJRB A C T I O N - B , m W STUDY t n l FINAL REFOET I S RECEIVED) IST " L tR" S5 - FOLLOW c -8 RESEARCH ! / RJZ030293 EID 112757 A Com m unity Exposure Guideline CCEG") is an exposure guideline established by H askett Laboratory. The CEG assumes a 24-hour lifetime exposure by all, including the m ost sensitive individuals, in an exposed . community population. Exposure above the CEG w ill not necessarily result in any adverse effects. W here data indicates that the CEG m ay be approached or H askell, the appropriate Business and Legal evaluate, w hat action. If any should be taken, It is the Company's intent to m aintain exposure below the CEG. EID 112758 RJZ03O294 rSHSDEJIQfilS -TEFtoir AREA EEBS 1984-86 1987-88 1989 1990 1991 POPULATIQM 108 58 41 21 3 < =1PFH C%1 67 50 59 9 N/A <=E!EHU3e1 92 90 83 100 N/A RJZ030295 C tst, 1/2/92 EID 112759 EXPOSE! Tn r"8- AFFicTS^LivER^UNCnON^AS^HEASUREO^BY B L o K I v E U W SSOT^LOH. AF. AND 8ILIRIBIN. , W l H ^ 9 l K S RP i u O EES IM ME F1VE " ASSI* NIS CONTROL: 1 OF ALL VM EMPLOYEES WHO HAD NEVER WORKED '"TEFLON". sshs m s t r a ? *" " " CONCLUSION: 1. l u m s W o S ^ 1EXfeE*TORc" .HEALTH 2 FEP WORKER AF LEVELS MAY HAVE RISEN FOLLOWING C-8 ' EXPOSURE. 3' 58 IxPO^URE^' P W " n vniDY UPDATE ESTIMATED COST: $4S,0t* ESTIMATED COMPLETION: FIRST HALF, 1992 REVIEWED WITH KAItMt AND LI60, 10/4, DECIDED NOT TO PURSUE C:s l g 1/2/92 RJZ030296 EID 112760 ) ; C ri b i o a c c u m u l a t i o n in fisa BACKGROUNDt BIOPERSISTENCB IN WAN, RODENTS _ HO DATA ON TISSUE BUILD-UP, STORAGE SITES IN ANIMALS; - DISTRIBUTION OF C-B DIFFERS AMONG SPECIES; WITHIN SPECIES (MALE VS. FEMALE) WOULD C-S BE EXPECTED IN BUILD-UP IN FISE? - OCTANOL-WATER PARTITION COErFICI^T ESTIMATES - OCTAHOI, vK&y LlTrtB TO ACCUMULATE IN FATTY tissues of organisms - TISH A TT H E i R n E MAA N S T(OFRIANGDE CS-BI TBOEUJNDi 'T OS SPKLASSSMAS)* ^ - EXPERIMENT TO ANSWER PROPOSED TO POLYMERS BUSINESS COST OF EXPERIMENT APPROXIMATELY 1 YEAR, 50,000 /7 17 RJZ030297 EID 112761 C -8 TRENDS IN AIR WASHINGTON W ORKS R.ZIptet rflc/11/91 86ZOOzra E ID 112762 z6-STRATEGIES I, WE WILL COMPLY WITH ALL FEDERAL, STATE, AND LOCAL REGULATIONS GOVERNING THE USE AND DISPOSAL OF C-8. II. WE WILL CONTROL C-8 EXPOSURE TO PERSONNEL 8Y BEING IN FULL COMPLIANCE WITH THE AEL <0.01 hg/M3> FOR BVLOYEES AND WITH THE CE6 <0.0003 mo/M3 IN AIR, AND I PPB IN DRINKING WATER) FOR THE GENERAL PUBLIC. III. WE WILL COMMUNICATE C-8 INFORMATION TO EMPLOYEES AS DETERMINED BY SPO & SITE MANAGEMENT AND TO THE GENERAL PUBLIC AS DETERMINED BY SPD & SHE MANAGEMENT WITH THE ADVICE OF CORPORATE EXTERNAL AFFAIRS AND LEGAL. IV. WE WILL CONTINUE TO USE C-8 FOR THE MANUFACTURE OF FLUOROPOLYMERS. WE WILL CONTINUE TO REDUCE C-8 EMISSIONS TO THE ENVIRONMENT BY UTILIZING GOOD MANAGEMENT PRACTICES AS REQUIRED BY CORPORATE POLICY. V. cue. to* Li UJO&* T RS.ACH jg* U 9 - r 66ZJQZ0Zm GLOBAL C -8 USERS site WASHINGTON WORKS DORDRECHT WORKS SHIMIZU CHAMBERS WORKS SPRUANCE PARLIN U.S. MAJOR CUSTOMERS NON-U.$. MAJOR CUSTOMERS M B IT - III 71.1 M 31.400 15.H* 2.000 1,501 2,500 - 6,150 4,960 RJZ030300 EID 112764 GLOBAL C-8 ISSUES UASHTIIfiTON WORKS - LAB DISCUSSION - C-8 LEVELS IN AIN - RESOLVED - OHIO i DELAWARE RIVER - 6ROUNDHATER - LANDFILL - LETART & DRY RUN - C-8 LEVELS IN AIR - RESOLVED - MERMEDE RIVER - LANDFILL SHIMIZU WORKS - SU6URA BAY <!HlMBgPS MQRKS - RECOVERY IN FACT UNIT SPRUANCE - JAMES RIVER MAJOR CUSTOMERS - AWARENESS OF HAZARD EID 112765 w w y /* .6 i. m m m m mm*m msm msuwsmlsi \sl CG~ / PP EXD112766 RJZ030303 EID 112767 RJZ030304 EID 112768 to 4.2 , C: 1.1 **6: ,8.8 / 4 J ^ 4 ^^ _: 7.1 \' V' S Jag. - ^ H\ - fc.1- s s tm* ** RJZ03Q305 WELL 336 W E L L 331 C -8 RESULTS (PPB) DETECTION LIMIT: CH2M HILL: 0.1 PPB EXP. STAT: 1.0 PPB H v\ // // \\ II '/ W // u <> ts I EXD112769 RJZG303Q6 EID 112770 * NUMBERS ARE LBS/E EID 112771 RJZ030307