Document BqLqMNYaaXq4O0y2apaYo0JJ

I N D U S T R I A L H Y G I E N E F O U N D A T I O N O F A M E R ICA, I N C. Mel l o n In s t i t u t e, 4400 Fif t h Av en u e Pi t t sb u r g h , Pa . 15213 A u g u st 19, 1965 Dr. R obert A. Kehoe D irector, The K ettering L aboratory U niversity of Cincinnati Eden and Bethesda Avenues C incinnati, Ohio 45219 D ear D r. Kehoe: This is to thank you again for your k indness in a g re e in g to m e e t w ith D r. Jen sen and m e la s t S aturday to d isc u ss our c o u n try 's r e s e a r c h n eeds in the a r e a of E n v iro n m en ta l H ealth. It w as m o s t in te re stin g and p ro fitab le to m e to be able to h e a r you and D r. Je n se n c o n sid e r the toxicology of le ad froim different vantage points. Don F o w ler's participation w as also very helpful, e sp ecially in re g a rd to p ra c tic a l co n sid e ra tio n s co n cern in g r e s e a r c h in the lead industry. F ro m our d iscu ssio n , it would ap p ear that se v e ra l approaches a re needed: 1. B e tte r o b serv atio n ^ev alu atio n and re p o rtin g of e n v iro n m e n ta l and occu p atio n al h ealth d ata on p o pulations w hose a b so rp tio n of lead h as b een quantitated over a long p erio d of tim e, using epidem iological techniques to identify and m e a su re any insidious effects on health or to docum ent th e ir absence. 2. P ro d u ct o rien ted stu d ies of the tre n d s in en v iro n m en tal h ealth and contam ination. The organic lead p ro d u cers of anti-knock com pounds over the p a s t 40 y e a r s h av e p io n e e re d in th is a r e a and se t an ex am p le of w hat is possible through cooperative efforts between private industry and governm ent. O ther exam ples m ay also be cited of su ccessfu l p ro g ra m s in the chem ical ind u stry . The m o st im p o rtan t b a r r ie r s to p ro g re s s , m ay be overcom e through im proved application of existing know ledge, and our chief need is for im proved leadership ra th e r than additional data. 3. C hanges in body sy stem s induced by chem ical exposure axe being studied in a num ber of univ ersity and p riv ate la b o ra to rie s. A n overall evalu ation should be m ad e of w hat is being done, in an e ffo rt to in s u re sy ste m a tic coverage of the m o st im portant facets of re s e a rc h , and to help avoid "gaps" w hich a re a lm o st certain to occur o th erw ise. A s m entioned by D r. Jen sen , benefits to be gained include a b e tte r understanding of b asic hum an physiology and genekrophic v a ria tio n s , a s in the c a se of m a tu ra tio n of h em o g lo b in in the p re se n c e of elevated lead lev els in the body. KE 001081 3 N29901 N D U S T R IA L H Y G IE N E F O U N D A T IO N O F A M E R IC A , INC. D r. R obert A. Kehoe A u g u st 19, 1965 Page 2 Y our le tte r of A ugust 16, su m m arizin g your feelings concerning the ro le of the US P u b lic H ealth S erv ice N ational E n v iro n m en ta l H ealth S ciences C en ter is a p p rec iate d . It w ill lend co n sid erab le su p p o rt to the reco m m en d atio n s I have m a d e , and I shall be able to u se it at the m e e tin g of the R e s e a rc h T ria n g le Institute panel next week. - It w as a re a l p le a su re to see you looking so w ell a fter your w e ll-d e se rv e d v acation in C olorado. B est w ish es to you and M rs . Kehoe for a safe and interesting trip. Sincerely yours, d eT /d p R obert T .P . d eT rev ille, M .D . M anaging D irector P .S . I have ju st receiv ed the copy of the 8 m m m ovie film of you and M rs . Kehoe in G en eral H a ll's office, follow ing your aw ard of the U .S. A ir F o rce C ertificate of A ppreciation, and it is enclosed. My apologies for the delay. I d id n 't expect it to take so long. IS. K 0010G20