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3M 3M Corporate Toxicology and 3M Center, Building 0220-06-E-03 Regulatory Ser0ces St . Paul, MN 55144-1000 651 733 1773 Fax Certified Mail P. 3 RECEIVE D ~rr, ~- *,s~ L3 :' a " 07 JAN 16 AM 6: 15 January 8, 2007 Document Processing Cente r EPA East - Room 6428 Attn : Section 8(e) Office of Pollution Prevention and Toafles US EPA 1200 Pennsylvania Avenue NW Washington DC 20460-0,JQ:k NO CBI RE :--- TS .~i. 8(E ) SUBSTANTIAL RISK NOTIGF,'tON : :PFHS and PFOS ; Supplemental to Sulfbnate-based Fluorochemicals, Docket Nos . 8EHQ-1180-374 ; 8EHQ-0381-0394; 8EHQ0598-37 3 Dear Sir/Madam : In July of 2006 3M notified the EPA that preliminary data had been received from a study suggesting an effect of perfluorooctanesulfonate (PFOS) and perfluorohexanesulfonate (PFHS) on body weight, food consumption, and serum cholesterol in 15% dietary fat fed E3 Leiden transgenic mice in vivo . The final report for this study is enclosed . If there are questions, or if additional information is needed, please contact me at (651-7371374) . Sincerely, Deanna J . Luebker, MS, PhD 3M TSCA 8(e) Coordinato r I Enclosure CONTAINS NO C61 ~ ~jg3