Document BXa8MBVkoDN6ywoDDr0BEOyL
wl
AR 226 -- 3468
2
i
72
ps
000694
|, 7 1. ou PontoFNewo&Cuomrpasny
WiNGTon, DELAVARE
.
|
.D ;
i
March 15, 1979
ERsouAL mw comeromweraL
C.hir6. oar 513265
FLUORcGrSaUBLEEARCSTAvNoTR.KSSTUDY
(Ref. Lefter from RDR to PGC, 1/23/79)
iunlfaotrimoantioIofnn rthteeospaDoinnsaspleeynztseoarotyhuerVidrsaeitqtausessattnadttiosDtitishcaeablpilllyai,nttyweWfaogrreeacdeidinivcteiiddoennaatlstabi-n
brotfohekeeemnxppldooosyweendesabnyidnbccooadncythrsoylsgrtouegpmrso.wuhposWhe(aAdvtetaarbcnhoamriemsnaetlVi)nl.fiovremTrehdofsueonfcdtaittohene
vneurmsber tests:
ploy
Bi
group
We performed a "chi-square" test to test the significance
oHsftaacdthiiesftfietcraaeblnllecyesshsboiwgesntiwfoeineclnaynttht.ehoesxepodsiefdferaenndcecsontthraotl vgerroaupsf.oundThetoabt-e
edxipsoorsdeedrsgI,rnouatphesfiocgrantiebfgoiotcrhayn,Dtilsy"pAehlnilsgearhgreiyrc,ViinsEcinitddsoecnrcaienndew,iDsisaanfbdoiulMnidettyaibnoWlatighceet . Oifnciddieanbtest."icsThfiustvheasexaptotsreidbutserdoupi.n the report to a higher number f"oSrkin"maenndtTahleceealnxldpuolsaberadycthgiosrnsoeuuueprso.at"lisco" sdhioswoedrdesrisgnainfdicafnortly4ishoirgdheerrsnoufsbers
mpaorreedDtiosIahb5.eilciTothnytirsWoalgdeigfrieonruccpin,dceneotnsisthfheoirgohtclhiyerrcuslhiaagntndio,friychaednditsecao(snpes<si,0d.e0r50a31b)lc.yon atlhaegnaovsaiislEaxwbpillteahnidanattiaot.nhseseIftorgevnotouhrleadsle bdceaitfhefegelorbrfeiunelcsestaocccafoniunnndotteodbuet fwofrhoautntdhespfercoimfic aifferonces between the. tuo oroups.
~~
`CompanySanitized. DoesnotcontainTSCA CBI
000695
y
.
Ll .
functionAl7bto:heotuetghhuensatihfneroentruaembnblteyerhoi1fg5heneorntplinos.ytetaehtseiswteiixtcpaholsleaydbnosgrrimogaunlpifil(ci6avnectronBTGeeo4ei9Eny)ed"bsueNraevtveeirhltnlhaenelcxeecsesvs,osulrtdhioskbdeoaftaadvddieosvaeblslouepg.ignegstlitvheart atiheseaesxep,ose5d0
hEbICAL DIVISION
omy Othe
MEsapiniaadngeeemyriPoelrolgy Section
Asveeiamcsna.
--~
000696
N J ORGANIC FLUORINE IN BLOOD
Group (spe size)
. een ORGANIC FiuoRine
3Dara
GENERAL POPULATION (106)
00002 10 0,13
PLANT OFFICE WORKER
.
0.02%
0.01 10 0.06
PLANT WORKER =GENERAL PLANT WORKER ~ Lon .
0.13 10 1.13
SERVICE IN F/C AvEA
Newer par Louver pLanT
0.970 9,1 5.97071
Du Powt Dara
|
HILMINGTON conTRoL Group (25) Bor)0.00-9038 te
DD
Cuaers Hors crower (55)
or
(Gl oF 55) 0 - 0.37 *ee
10,15)
Concusions
-
|
Cuntpens FLUORINE
HORKS EMPLOYEES DO NOT HAVE ELEVATED LEVELS oF IN THEIR BLOOD AS WAS REPORTED FOR 34 WORKERS.
oReanic
THe Wea THAN THE
VALUE For CHAMBERS WILMINGTON controL
HORKS GRouP
EMPLOYEES WAS SLIGHTLY HIGHER [0,15 versus 0,091, sur aL
|
|
VALUES ARE CONSIDERED T0 BE "NORMAL" (<1 PPh) EXCEPT ONE VALUE
IH THE NILNINGTON CONTROL GRoup (10,6 pp).
|
* BY DiFreRence semeen TOTAL AND INORGANIC FLUORINE
* excep 2 vaLues 10,6; 0.78
** [Mep1an vaLue)s
ST except 1 vaLue 0,89 peu
8
600697
yp
Taos 1
Ueshis
`CONOCFPEERFLNUORTOOCR TANA OATETINI BLOO OD(Nx)
Saple pics Tased -- ---|| c0omm ------| | esmm
6DaAtneadloysstse. d (G1,mVErFA,T:
o6/e26m/81
o0.o00n7
Le6/26e/81
0n..d.0
(0) JpAaoccaikyeesd'tecoBallsuoomdnd,eGsGCcurisanbaeCldhyreofimosaLtwaoibgtrNhaapthphiecordtNi5eu5ot-rh3a6o-7dni(o5"r:DieaStneeiarcbabiosnneastt.hio4no2/oofosebphetsbrrfboimouinonnrteosceetruaenrotee.
-D ) EcR Aeoltntichaeoanuctgo erhsattuihnoencsearnhataarlaiyansttgeysive115nsa1siynp1ebI0c7oi.afSieFclliauCttoiyrEvieofeosrr1faopnSredcoctoriosvmoandrceaivonociotanatmitsooiisnctrke Bh(oaeincideeooosnnrstsinaleSeEs),
w5cfoo0nr0c0aQnu7ta.rnattiiStooanntseiodanot1estchta0et.d00s7a1r4gVe.a)c/sa.nLnnorteTpbhoecewdeeedltleoctqriroosnnteiTreipseidtntedwoiackmh [o0orrreon]tse<setorrrileeEs.s oomooine.
hich camot be distinguished fron reagent backgronms: 8) on
CompanySentized.Dossnotcontain TSCACBI
2 000698
|
|
~<D |
E ||
|
|||
ase CONCENTRATION OF PERFLUOROOCITABLN0OGDA(T2)E
1c Sate
| nm
oy|| 1n5sm
----_--| |
om 2
[-- ARS
yy || 2rme
---
a22/m81
T1228
-- \a--1m 20
--
--|
o123e/81
i | 20
NT
[--| ie
DGa6teAAnnaallyyezted
I 712181
7112/8/181 pa sm 29/81
7/29/81
em 7n/2o8m6 7/29/81
nim 129781 79181 7112209/8m1 72113300/0811 wrm
Sts
His 0.0
0.25 --
on 0.015 0.033 na.
0.010
oz -- 00..000025 < 0.007 0.016 016 -- 0o.0s07 --
0.032
0.08 0027
_-- | is
7/28/81
0.100 _--
(@) ApAcantcaakleydsitncsoBlalusoomddn,e'sGCcGraisAbneCadhlryosimtnastLovagibrthaMpehtpihcoedNre5t-fh5o6dln7",uos(5ot".DaornScoeeoiarenfioanrcadit,dioa4ns/3o/fc8a1lP)le;bcrtualscuiionorgnooctsthtaeasnodiacrd.
(6) EtAcaoolttntiachnleoanuctgoerhrsagattnuihinoeccnaesnrfatlalauryioesnritigsynieveiiaansn+asilnpy1esp0ct1pisaf.eiclalal(utlooiyptveienfeoFrstf=ooprne0d.re4fSr3lod3uaopdxareroviopispcamottnapineoworniat.ttlheuoTt(rhhaoeecoisdSeooasounerolrliess.Malaatotcfsti)d,)
cfoonr70c.aq0nu0c7a.rnattiNitooanntseiodnient1etchta0et.d00T7a(nngJ-edg.F)/csa.siusotrTehhpeoodrvetetedelctfiqoruoannstaLimitpmaiittoesd5waiatvnhd 0a.[r0og0e]4 r=eSpgEo0/r.st0,e0d4 buapsotm,
WRLC cannot bo distinguished from reagent backsrousd:
:
( Prerneuvlitousoflytahenaliynzietdialsenapnlael,yairse-aonnslBy1r-e2d179forvascom0p.a0r%i,sornepwoirtthedrep1e1a1t3/s1a.mple 81-3189;
`CompanyBanitzed.DoesnotcontainTSCA CBI
@
000699
a
Vat
sla51
MALYTICAL RESULTS AS MICROGRAIIS PLUORINE/GRR! icon
: Lrg DoE
Croup A 0.032 L015 033 Low -062 077 140 "02s 064 , nso
Group R 0.05
Ea
Grow C 0.013 -016 wD
i : #
Group D* pro
01s) fon Clio
ron oul fos 120
Ee
Grows E Grows F 0.020 wpa wpe Soom <oomes L010
:
oe
ed
sommes
-00239 cc elt . eel DL LT.
D
3
S250
=
150
-
SP
ah at
it
Fangs
Mean'
o.oMs-25 T= Co-.o16 0.00712 0-020
0.0805 0.0590 0.0097. 0.0356 0.0088.
-
0
simples 715 i, Employees' 15
103 hs
1
FR
PE 5S
Overall: Rasige 0-.25 Mean 0.05 Samples 33 mployess 20
.
|
`77%. Te
iPnreGvroorukp
D`and(Ppraos)t.-orTikme.spelcaipsmeenbsewtewreeentsaakmepnlefsrowmas4
(Bost)
|F
3s-r3p:lowyeeeess.
.
.
27Ak. 1"i,%
NTaroheneerloedvpeeotrrectteledidm.siitmpZfloeyrroaqsucao<nn0tc.ie0tn0at7tr;iaotnhioowniesv:ue0sr.e,0d07tihnleacn0do.mo0pw0u7teirnvgawlumaeelawnesa.ss
fps
+h sed in calculating means ro
3
1
000799
rk PR Opens special [FLvorive --iw-vzine Semele Roz Mac
wang
8--
.
.
TTBO VVIISSIITT sStPeExX.. oovN dDaAreTE:
~.
--EEmeeLiooxxeeee
Baseline
RINE
Follow-up
INE
Q@y, pn J @,, m SS
Ls A Oy an @iy, fy
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vy -
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amy
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oofCGotdtede[s--mm5--
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000701
| Be
ilefre
FLUORIDATED DATTIE ME uring vo
WATER TosTH
NAME NUMBER SWeLY PASTE
Base-
LINE
Final
samp
yes ne. We mm Mo pon
yes no ls am Mo py
yes
ves "ls pm
hh om
Ces yes ho am Wf pw
The baseline urine
yes
Semple
yes
wins
"he Py
voided afer
"hy py
worker
had_ been away. from worksite petenhal exposvte h floorides
for. a} least 42 hours,
-
been suThbejudfeidnalherinweo.rkssiatmeplpeolewnahselveerxdpeodsuraeftFerr
~o
tombe had
a momen.
!
of 48 "hoves clock. time.
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HRS.ON JOB BETWEEN SAmites
en 220
22
cee ; 23
15
MUMGFRpAecLMiTESR, |REESRE AFTER_pieieor
"Me sa nm.
B2...28 0 |_
3440.04. 3.9. bb. 27
Lb 42 oo
.
pNositoussHsc_kRescpoecmimmeenndasnhailoln.not(CoiycteeadD.ocu7m0ent,a4r-d898)sh=at Thmeit
exceed
than
He
30
pre-wnck specimen Af a piclkp raster
illgrams Fp Aiter of "orine
@
000702
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PERSON amp coneromETRL
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me EE ---- obymertaston ay
--
---
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[S- pin
| --
Eintaning
-----
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cxcanne rposaoes mm sooo snes
Baam afnrecmey
comers
EE EE : 8 er
3097 6
-
we
warn 66
mle
sme a .
ass a
PE
047 assem, 12/72 to present
233 ERxpiosmureianece21/97648, rama polymer 052 5Espo7en6cy5imaetlrotpjiorabet.sieonntR.sehloiuetf 1onggrhuememtkar
358 PP. 2.0. 8/62 to 3/63, FER polymer
A1z3a/t1iotno8p/r6e9stenot7/70, polymerization
5.6 12/72 to present, others Soba since 5/55
ePsCte mp0. 3/8 to 10, simeriation
EO
meant
23 376 to present.
2.06. DoiTsppm.er5i.n0a.ti9i/n715/t7o67/672p,reassetnatteis to 063 pDaeitarip led tgo polyarization 65 days dn 0.72 pSeottatiaedtto10gwreainmsiaarapooflySmIerTisSa.tion
SFPIeONxWEsDEoRn/DISPERSTON
.
Folymerteation
-
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-----u . 6 6 439 7rr5.,bTyoetrmsmerianatstioiosnp.4/55.50.to9pr%esetnot.
=| ow
108" 62117) 21T .22 --.Siermveirciee:aopveiroantorsiJnocebs2/66/85. to 6/60,
()Previous blood samples taken inJune."is= vid Ffor
Heo
@
Redac- Ptrievadcy
000703
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wrox am Forroeomcnoiion
--
= Polymerization (Cont.)
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(9.53) 8.357
---
wz 6
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5.30
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6.90
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826 to sresent.
P4r/e6v2iotuosp6reyseeanrts,. others job
:
#po2l.ymeP.r0i.zatainonb2e/y7e4r 7th66pretsoeh3t/e72, p3e/6z3atteorpr1o0s/in7t1,-e45x./cept sonemer
190 to present.
.
1/75 to present. :
34062s ptroepvrieosuesnt.yesaiss:vice operator 1/5 to pecans.
i3z7a6tio0n 80//7708 2to.predsreynetr., poiymer-
S5e/6b5a tadodpirteisoennst',Sseyrovuriec:e operator
3/79 to present.
.
S4h/e7r7attoonpr3e/s7e5ntt,h F4/E11service
Fizra.tioanry8e/r7810/t7o5prteose4n/t7.7, polymer-
-_--y
> y > -----y
-_--
3568 .
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ame
0.58
PFs.oapm.eidrnrya.ermpasonldpyo2mie.yr0mi.esra2it/zi7ao5rn-i5o/4n77,69,
:
present."
ao * PSoelryvmiecsetoipaetriaotnor11/S7ob7s59/p7r2e-s1e1n/t7.7. 523.8 bo preset
=. ) Previous blood. samples- taken in>`sune. it
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Rodacted-Privacy |
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000704
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aes 4
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Redacted Privacy
| ----Comews
leinacion LogLag
Pop. Dryer since 1/78.
FfPy.tbervtedr 08 bicp. 5.0. 3776
Sesvice Operator ois 5/37 to
.
32a/a7 npresrenett7pr.apceyter, 3/79 to present a1 3 fom.
rr. prctout. Tore4 se,wn 0
12/72 to present 2.2. beyer ma
En 1/79 to present Disp. and
5. packout.
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--
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0.90 T 1976 to present.
-- ---
wsros 2h.e10Co bm157i6atao0mpreseent. pete. r
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wae
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mRIsTe 1976 to present. Additional
DP
---
m8 6
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:
3
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ra
1976 to present.
-- "
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4.96
Slr 1976 to present. Additiosal
-_--
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n 10/77 to pr resent. agaitiony
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6 wae
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foi) ee
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Sestuorts Jutoratortens
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0.28
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(18
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558///767287 t1tno13p1/r3e/6s79e2,n,t.SsoemrPpvipincaietsyshpisenergisvotiipcneerator Cperator 14/75 ta Tyr4s 3775 6a 11/7:
4/71 to present.
2/75 to present. amr vg presse. 2/63 to 10/72, 375 to present: 7S7t7 ato pSrresaent. servicn opexator 91/05/57-24/to2,presseernvti.ce cTpeetcoantoerx3p/o6s3u-r2e/6
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-sTC)
Brevions
.
bloodsamples t=aken tn
ume.
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1ar0n/o3u0g/h7t5ysses _--~PY
Redacted. Privacy
sta :
0007077