Document BVda62MD4nNEYB5de3N50B4o

Dr, Bonnard Teagarden 1 East Ninth Street Hew York, New York Dear Doctor Teegarden: I am sending you two mailing tubes arrive in good condition. The one cont tube for a sample of blood, together with a sterile needle of special construction for taking the blood sample, the needle being in another tube; the other contains a small bottle for obtaining a sample of urine. The blood should be drawn directly into the tube by means of the special needle, and without using a syringe. 10 cc will be sufficient. The stopper should he put in tightly and recovered with the filter paper cover in order to prevent any contamination. No anti-coagulant should he used. The needle should be replaced carefully in the receptacle with cotton at either end and around the hub to prevent breakage in transit. (If the needle should be rendered unsterile by chance contact before use, it may be sterilized by gentle flaming, but `not by boiling in water). The urine sample should be voided directly into the small bottle until it is almost filled, in the presence of the examiner. The latter should remove the cover and the stoTimr and hold it In his hand until the sainnle has Kt BT v 3-31-1937 - (2) I trust you will not be disturbed by the detailed instructions I am giving, hut it seems best to be explicit. As to the suitability of such samples for diagnostic pur poses, I think I,,should point out that I usually obtain one or more large sample of 2 1/2 to ty- liters of urine when I base conclusions on the urinary results alone, but when I . can obtain both blood and urine I am fairly well satisfied to obtain a small sample of urine, the latter having the great advantage that it can be obtained in the manner in dicated without undue risk of contamination. If the results on the blood and urine are in agreement they can be accepted as mutually confirmatory and satisfactory. If one is high and the other relatively low or vice versa it is advisable to check the urinary result through the analysis of a large sample. In this Instance it seems more convenient to obtain the small sample and if necessary perhaps we can . get a larger one later. Such a procedure is usually unnecessary. " It occurs to me that you may be interested in looking over some of the observations which we have made in relation to this problem, and also in the general study of lead absorption and lead excretion, and 1 am sending you a few reprints under separate cover. The work on normal lead, and on lead excretion in certain trades Is to my mind to most interesting part of our study. . Please accept my thanks for your courtesy both on ray visit to your office, and also in obtaining the samples for analysis. Cordially yours, RAK: vn Robert A. Kehoe, M. D. Kettering Laboratory College of Medicine nfiden Avenue Cincinnati, Ohio He 001.1774