Document BRdBYgOZeb1q53JzodpgkMYX

BFG35931 128 Annals New York Academy of Sciences In the future, periodic control examinations of ail PVC workers, especially of those engaged in VC polymerization, at short intervals employing sensitive methods should be obligatory unless it should prove feasible to eliminate com pletely any possible afr contamination. Some of the many scientific questions connected with the problem of vinyl chloride disease may not be answerable until results of further extensive animal experiments*1-**'*1-'*' and of prospective and retrospective large-scale studies'* as well as of continuous monitoring of working areasu'UMM-'" are available. References Aoam, V. G., A. G. Huvos A S. I. Hajou. 1972. Malignant vascular tumors of liver. Ann. Surg. 175t 375. ai tmi.ni,.L r. 1967. YliiyitMOftne ptucEsses. eiw.ui. Cm; 7 HMamh a?R-3. */- Amm/llir f p lpA7 Ll.ft..f. -V rii... Itug-US {.^iitl-Hty 219. ' AimiAin i p I9fl7 Polymerisation nf vinyl ahlariilai Clinm Tnr 71 (Mur BV 151. atnmir.nT l P Vinyl iihl*^*1ilt ftlyin nr liini ,iy |||1[`'|||||||< I'"""1111 _Al*>iciit, L, P. 1987. Vinyl Ltnamte pulymu izallon by amuUion,.hulk an<t. mill,. lion prnrrttrs Phrnii Du- 94 (July 3)."HT Anciielescu. Fl., M. Otoiu, E. DoaatNEScu, L. Haoi-Parasciiiv-oossios, Gii. Dobriniscu & V. Oania. 1969. ConsIderatU clinico-patogtnice asupra feno- menului Raynaud la muncitorii din industria policlonirildc vinil. Med. Interna 211 473. A <r-~Aumn, 0. T: 197*4. liiUustlhlllysIgiiifieeiit eiganla chemicals1 (Pju~3). Chun. Sngr4S-(MasctuUM2. 9. Blaoer, E. W. I960. Klinischc Grundlagen der sechsundvierzig meldepAichtfgen Berufskrankheiten. Urban A Schwarienberg. MUnchen, West Germany. 10. Daaoer. E. W., Ed. 1961. Handbuch dcr gesamlan Arbeltsmedlzin. Vol. 11/1: Beriiiskrankheilen. Urban A Schwarzenberg. MUnchen, West Germany. 11. Bagiiirzaoe. M. F., E. U. Bertel A P. Schumacher. 1971. HKmangiocndo- theliom (Reticulosarcoma angioplasticum) der Leber und alte Echlnokokkus- infektion. Acta Hepato-Splenol. Ill 224. 12. Baretta, E. D., K. D. Stewart it J. E. Mutchler. 1969. Monitoring exposures to vinyl chloride vapor, breath analysis and continuous air sampling. Am. Ind. . Hyg. Assoc. J. 30t 537. 12 Basalaev, A. V., A. N. Vazsm 8k A. G. KoiiTxov. 1972. K patogenesu izmenenii voznifcayuslitikh pri dlliei'nom vozdeistvii vinilkhlorida. Glgiena Truda Prof. Zabolevaniya 16(2); 24. 1-1. Basu, a. K., i. Boyer. R. Biiattacharya. K. C Basu Mallik 8k K. P. Sen Gufta. 1967. Non-cirrhotic portal tlbrosis with portal hypertension: s new syndrome. Pari 1. Clinical and function studies and results of operations. Indian ). Med. Res. 55i 336. IS. Basu Mallik, K. C, K. P. Son Gufta, A. K. Basu.'S. K. Biswas, N. C. Pal it i. Uover, 1967. Non-clrrhotle portal fibrosis with portal hypertension: a new K. --W: syndrome. Part It. Hlstopathologlcal tlacK, H.; W. DuuiiLearMi Haw is, Bi studies. Indian 1. Med. Hiam, IferSietuHaa* dl Res. 55i 351. R: Tenner. 1988. 17. --TVtterdu-Leusnisktuila, frK. fluiattauM Vartng. Stuttgail. WtsrTj2riffa'ny. Becker, V. it k. DOsscitaa. 1961. Uebcr dss Hlmangioendoihellom der Leber. Acta Hepato-Splenol. 8t 3S6. 18. Bia1n2c14ii.i, L. 1970. Zum Problem der Lcberitbrose. Schweiz. hied. Wochjchr. IOOi 19. Dover, I. L., X. ?. Sen Gupta, S. K. Biswas, N. C. Pal. K. C. Basu Mallik. F. L. In*? !< A. K. Basu. 1967. Idiopstbie portal hypertension. Comparison with-:ht . <! hypertension of eirrhoais and axtrahepatic portal vein obstruc tion. ; . -..-r.l Med. 66(1): 41. .20. 21 batT. j\Zi.;. Brcn?i:" . j'*. Vinyl chloride and cancer. It 590. ?. Scsiaffner Jk H. Poffer. 1966. Fat-storing cells (lipocytes) ir. I'.'Jmr. I'-'rr. Aceh. Pathol. 82i 447. UKCJ'j. 13. Patologla da reslne polivinillche. Med. Bull. 52(2); 102. TOOOZSfZ Marstcllcr et at.: Splenomegalic Liver Disease U9 - 23. BrQiil, W. 1966. Zwischenfklle und Komplikationen bei der Laparoskoplc und gezielten Leberpunklion (Ergebnis cincr Umfrage). Deut. Med. Wochschr. 91: 2297. 24. Canada, Oefartmcnt of National Health and Welfare, Industrial Health Division. 1949. A guide to the diagnosis of occupational diseases. King's Printer. Ottawa, Ontario, Canada. 25. Carr. J., R. M. Burgison, J. F. Vitciia A J. C. Kranti, Jr. 1949. Anesthesia. XXIV. Chemical constitution of hydrocarbons and cardiac automaticity, J. Pharmacol. Exptl. Ther. 97; I. 26. Ciiatelain, A. 8k P. Motillon. 1967. Un syndrome d'acro-ostfolyse d'origine pro- fcssioncllc ct de coastatation nouvelle en France. J. Radiol. Electrol. Med. Nucl. 48:277. 27. Chemical Economics Handbook. September 1973. Vinyl Chloride and Polyvinyl Chloride Resins. Stanford Research Institute. Menlo Park, Calif. 28. ClIEMiaWIRTSCIIAFT IN ZaIILEN. VERBAND DER ClIEMISCIIEN INDUSTRIE E.V., Ed. 1973. 15th edit. Econ-Verlag. DUtseldorl, West Germany. 29. Ciienoweth, M. B. it C. L. Hake. 1962. The smaller halogenated aliphatic hy drocarbons. Ann. Rev. Pharmacol. 2; 363. 30. Chief Insfector of Factories. 1953. Annual Report for the Year 1951. Cmd. 8772, ll.M.S.O. London, England. 31. Cook, W. A., P. M. Giever, D. D. Dinman it H. 1. Magnuson. 1971. Occupa tional acroosteolysis. 11. An industrial hygiene study. Arch. Environ. Health 22: 74. 32. Coroier, J. M.. C. Fiavez, M. J. L8fIvre St A. Sevrin. 1966. Acro-osUolyse et Ifslona eulanees associies chez deux ouvriers afTccifs au nettoyage d'autoclaves. Cahiers de Mldecine du Travail (Association Professionnelle beige des Mfde- cins du Travail 4 fanvier 1966). 33. Creech, J. l_, Jr. A M. N. Johnson. 1974. Angiosarcoma o( liver in the manu facture of polyvinyl chloride. J. Occupational Med. 16: 150. 34. Croll, M. N., L W. Brady, 1. Brodsky it L. Stanton. 1965. A new agent lor splenic scanning: BMHP. Radiology 84: 492. 35. DaIILOREN, S. 1961. Thorotrast tumours. A review of the literature and report of two cases. Acta Pathol. Microbiol. Scand. 53: 147. tv36. Danisiievskii, S. L. A N. M. Eoorov. 1961. V komolckulyarnvkh soedinenii. Glgiena Trod nksikologii v khimii vysoiiya 5 (9); 26. 37. Danzioer, H. 1960. Accidental poisoning by /0 ion of two cases. Can. Med. Assoc. J. 82: 828. 38. Deesb, D. E. A R. E. Joyner. 1969. Vinyl a posiire. Am. Ind. Hyg. Assoc. J. 30: 44$. ' A/ :hronic human ex^ ugs jiurclKiiiiuls. too IL-J9: Ptmimrw.'W: l);tl II. W. Glrrrbu. I96f ^ Acadcmie IW. HtW I tHK.TPd. 40. Devionevielle, Dr. A A. M. Fluciier. H des r8sincs polyvinyliques. Service M6d' gique expfrimentale ires de Saint-Marcel, Vernon, avril 1953. As cited in TrufTert, 041. Diaiov, D. A T. neatTic. 1971. Profesii ) tv ca. Arhiv. Hig. Rada Toksikol. 22: 53. 42. Dinman, D. D., W. A. Cook, W. M. Wi h* check. 1971. Occupational acrooileo : /Iacnuson A Tit. Dit(j niological study. Arch. '0Environ. Health 22i 61. 0\ : 43. Dodson, V. N., B. D. Dinman, W. V MaOnuion. 1971. Occupational aerr (N . N. M. Nasr A H. J. _ ^ clinical study. Arch. En- vlron. Health lit 83. 44. Dominingiiaus, H. 1972. Kunststoilr h> S A) Eigcnschaften-Kunsisloff- sorten-Anwenduntcn. 2nd edit. VO A 45. DotlsFtliinHWtNVOMtilAinUwsn., HIII. 1I ^97r *3. KI^WunSIsVtHsStoVlMTWe ' Y rf. West Germany. ^I Jbcrfllchenvercdeln- Urn- formcn. 2nd edit. VDI-Verlag. DUsseldort, __"* many. 46. Dublin, L. I. A R. J. Vane. 1933. Occupational hazards and diagnostic signs. U. S. Department of Labor. Bureau of Labor Statistics. Bulletin No. 582. U.S. 196? ,__ 47. Dublin, L I. A R. J. VaneI 194-*/Occupational hazards and diagnostic signs. U. S. Department of Labor, Division of Labor Standards. Bulletin No. 41 (revised). U.S. ffoveniment Priming Office. Washington, D.C., p. 65. As cited in Dan- zigeF ` 64 OCCUPATION HAZARDS AND DIAGNOSTIC SIGNS 123. Turpentine SYMPTOM. CONDITION, OB DISEASE TO LOOK FOB Irritation of mucous membranes of eyes, nose, and upper air passages, bronchial Inflammation, salivation, headache, vomiting, abdominal pain and vertigo, state of excitement resembling drunkenness, irritation of kidneys and bladder, strangury, odor of violets in urine, severe irritation of skin. OCCUPATIONS WHICH OFFEB SUCH EXPOSUBE Art-glass workers Cable splicers Camphor makers Oementers (rubber) Compositors Decorators (pottery) Dry cleaners Dye makers Enamelers Enamel makers Feather workers Furniture polishers Ink (printing) makers Insecticide makers Japan makers Japanners Lacquerers Lacquer makers Linoleum makers Lithographers Millinery workers Painters Paint makers Patent-leather makers Petroleum-reflnery work ers Pharmaceutical workers Photographic workers Polishers Polish makers Printers Rubber workers Senling-wnx makers Sbelluckers Shellac makers Shoe factory operatives Textile printers Transfer workers (pot tery) Turpentine extractors Varniabers Varnish makers Wax makers 124. Uranium Uranium, reported to be one of the most toxic of metals, is a source of radiant energy. A high frequency of cancer of the lungs in Czechoslovakian miners of uranium is believed to be due to the radioactivity of the ore. Very little has been published on the effects on man of exposure to uranium salts. The con ditions reported include purpura of the legs, reduction of leukocytes, as well as U> Ui VO Oj U> diminution of red corpuscles, a reduction in urinary elimination of nitrated salts, and an increase in the chlorides. Experiments on animals with uranium nitrate are reported to show nephritis, glycosuria, albuminuria, gastro-intestinal disorders, degeneration of Uver, affec tions of nervous system. OCCUPATIONS WHICH OFFEB SUCH EXPOSUBE Dye makers Dyers Glass mixers Paint makers I Pharmaceutical Workers Photographic workers Tile makers Uranium miners Uranium workers 125. Vanadium 8YMPTOM. CONDITION, OB DISEASE TO LOOK FOB Anemia, cachexia, irritation of respiratory tract, dry cough resulting in hemorrhages, diarrhea or constipation, emaciation, involvement of kidneys, hysterical manifestations, melancholia. OCCUPATIONS WHICH OFFEB SUCH EXPOSUBE Alloy makers fo Dye makers Dyers . Ink (blue) makers Mordauters Photographic workers Sulphuric-acid workers Textile printers Vanadium-steel workers CO Glass mixers 3 126. Vinyl Chloride This compound is used in the synthesis of organic compounds, principally a reeins. i \ - SYMPTOM, CONDITIONS OB DISBASS TO LOOK FOB ft The United States Bureau of Mines studied the acute response of guinea pigs to a single exposure to the vapors of vinyl chloride. According to this Bureau, vinyl chloride produces in these animals unsteadiness and motor LIST OF HAZARDS, SYMPTOMS, ETC. 65 utuxia, incomplete aud Anally complete narcosis. The principal gross patho logical findings .were congestion and edema of the lungs with hyperemiu of the kidneys and Uver. This eume Bureau determined that men exposed to 2.5 percent for approxi mately 3 minutes soon began to feel dizzy and disoriented as to space and size of surrounding objects and complained of a burning sensation in the soles of the feet. They immediately recovered on leaving the chamber, and complained only of a Might headache which lasted about 30 minutes. 127. Xylol. See Benzol 128. Zinc SYMPTOM. CONDITION, OB DISEASE TO LOOK FOB Metal-fume fever characterized by: Irritation of respiratory tract, dryness of throat, dry cough, malaise, headache, nausea, severe chills with fever, pains in limbs, shaking In limbs, sweating, leukocytosis. Metal-fume fever may also be caused by fumes of lead, mercury, manganese, cadmium, ursenic, antimony, and many other metals. Metal-fume fever resulting from metals which may cause systemic poisoning should be regarded as s warn ing that continued exposure may have more serious effects. OCCUPATIONS WHICH OFFBB SUCH BXFOSUBB Blowers-out (sine smelt ing) Brass founders Braslers Bronse-powder makers Bronsera Core makers Gulvanlsers Junk-metal refiners Luters (sine smelting) Metalllsers Holders (foundry) Pourers (brass foundry) Nherardisers Welders Zinc smelters -1 3 z* o [*i .(H -1 c.. r> rnH IJ '(/> o -< ro.'.f Ml *r z> .T z: q ,j it tr. Z' z* X- -e" V> 'z 1 j i\ I