Document BRJ674JnvkwOm5ngv6Nkj2Z4w

Tifiti W: py: Cutneoi^ppli cation Natur; q M E xperiment Secretion .,___ Date Started August ;,30#9,S4^ 'v '' ' A^n^im^a^i#a b b i t 31 Gray Belgian Poe "" -^te rv,-;--W?"-'7 D e scr ip t i.o *4n-`o f T r e a t m e n t Date rinlfihftd December 21. " . , .. ~ ~ : ' ' . ' . . ; - --V.-'-,;'.-r7..rrt'>S `"M -.S* *;. .$?jr-.L '' 0*10 c.c. of pure lead tetraethyl applied to previously clipped skin of belly$ Given 16 such treatment from August 20 to November 25. November 28, put into metabolism cage to determine Pb. excretion. `Urine and faeces to be collected ^ in 1 week periods. Dec. 5 sample 1 taken. Dec. 16 returned to cage given 4 ";'r| daily treatments of 5 gms. of NaHC0,,, sample 2 was to have been taken Dec. 23,f CH n essscuofttinued and sample 2 taken for analysis Dec. 19. Died Dec. 21. Sept . 3 0 Animal pregnant. ' Weight 6 lbs. Oct. 6 Delivered 7 normal young no treatment for 1 week following delivery. : ' : \''-fi Oct. 9 5 young died because of cold. Not cared for by mother, taken v?f$i * from her and put in with No. 32. Exposed to vapor of lead ^e1, ' ; ' traethyl. < Dec. 19 Animal developed complete inability to raise head Dec. 21 Animal dead. Pathology Gross No necropsy. M icr o sco p io <% Mm An a ly se s Distribution Skin Tissue .. , . ~ Bones , Liver and. Kidneys^ Central Nervous.System 1131335y914f9j.Se2720-usgggtmmm^mavtsssss-*... p: Urine (Small sample) - .it. Faeces and Urine Sample X*j7 days Faeces and Urine, Sample 224 days "8L4127^o'4010s9452(tP,h mmmm^ggggssss.... . ui&a"0021/....8114232j4Lw'vy *'*'1h'PT&, 1 . .`4^1 5.89 mgs. Nil Con clu sion s K 0 0C5S73 N7426