Document B8aRwy05Mez24VpGMmoNjVwo8
CMA 0 0 6 3 1 8
Liver *nmtmiirctnm Cooes
Cl icoletion
Dr A Haas Adame, Air Products Hr f H Anderson, Vi llou Dr V C Horses Jr, Monsanto USA Ur John Burr, Air Products Ur Peter Baxter, KHA3 Ur Brian Bennett, Hi 11 bouse (20 cupieo - 1CIA, AFCI, Duperial) Ur httttv BcrOul, JUles Uoiversity Ur Ikssche, Dyaemit Nobel, Troisdorf Ur 1" W Beet, Fverberg Ur C Bishop, EHA3 Ur Boukiis, ASCI Ltd, Plastics Bin's, PO Box 1122,
Johannesburg 2000, South Africa Ur David Bryson, AO Division Hr David burgess, 1C1 Americas Ur David Uyren, Kemanord Ur J T Curler, BP Hr C Clle, Hontapuliseri Hr H Clisnce, VCK Tec lui teal Manager, Mond Hr P 0 Ulaue, APHK Hr Harold Clayton, Norsk Hydro Dr Coatessol, Chloe Chinie, St Pooa Ur U Dacey - NIOStt, Cincioattl Hr J G Bevies, Cverberg Sir NU-hsrd Boll, Vardan, Green College, Oxford Hr (1 Dupont, APH Hr H Lmmiuger, VK Ur V rnsl, Berufegenossenschaft dor chesiechen
Industrie, Nurnberg Dr Henry Falk, CUC Atlents Dr D H Ferguson, 1CJ Americas Ur U P Friedel, Derufsgeootjueaacbsft der ckemischen
Industrie, Heidelberg Prof L Col berg, Duke University Medical Center, Box 291^
Durlue, North Csrolioe 2V?10, USA Dr 8 1 Constonyi dr, Tenaoco Cheslcele, Saddle Brook (HJ) Ur Duller D llsrris, Uniroyel Inc Ur Donald V Billses, Diamond Shamrock Ur Itobart K Binderar, BP Goodrich (Cleveland) Hr J Hodgson, HAS Ur V A Jlogg - I ape riel Oil Ltd, Canada Ur J K Howard, Wellington Clinical School of Medicine,
University of Otago, Wellington Hospital, Wellington, New Zealand Ur N F Uusphry, 1C1 Auatralie Operations Pty Ltd, PO Box V}11
Melbourne, Victoria yXH, Australia Hr J deuverl, Chios Chinie, Paris Hr B B Jervia, Hi11bank Ur H H Johnson, HF Goodrich Ur Bruce JCarrh - Dupont Br It A Krueger, BF Goodrich Dr J P Luloine, Solvay
Hr J Luwrence, SPi
Ur F ] Lee, Victoria Ituspilul, Blackpool
Hief V K Laibach - University of Boos
Br U A Levl&on - St Burtholoiaew's Uospitul, London
Br P Lewis, CIA
Hr Lulivier, Solvay
Pixjf B H H HucSween - Western infirmary, Glasgow
Ur J H Kaillsrd, Hedixinische AUleilung, Suva,
Postrock 6002, Luzern, Switzerland
Prof C Hal tool, Bologna
Ur Hunto Huttiuasi, Montedison
Hr Hokka, Neste Oy
Ur K Hunteeeno, larc, Lyons
Ur A A Holti, Duperial SAIC, Buenos A ires
Br A Muon, Monsanto, Brussels
Hr H Hunox Houtou - Bio Uodaso
Hr S Nakamura, Ja|aneae PVC Associetios
Ur John J 0*Sullivun Moiul
Br B Owen - TUC
Br G H Puddle
Ur S Peglielunga - Huntedieon
Ur Hans Popper, Mount Sinai Hedicel Centre
Ur J Puesbeig, Hacker
Br Jane a Furdham - Canadian Centre for OKS
Hr P Weagaes, Norsk Hydro
Br N Seracci, larc, Lyons
Ur Bevid Seronne, Uiaaoud Shurock
Ur Paul H Smith, Lleodough Hospital
Ur H Spirtaa - NCI/N1U Betheads
Ur Carol Stack, CHA Washington
Br J Stafford
Hr Stabnecker, HASP
Prof C U Tamburro - University of Louisville
Ur Gary Ter llaar, Llkyl Corpoialien
Ur U Terwieacb, CWU
Ur Gille* Theriault - Hctiill University
Prof Br Thleas, BASF
Ur I Thiia - fveaeeu, Norsk Hydro
Dr W Tordoir, Shell
Ur T It Torkelsoa, Dow
Hr J It Wallace, Faso Chemical, Surnia, Canada
Hr 0 Wejdling, Kumanord
Hr H N Wheeler, UCC
Ur J Uiistos, Hi 11 house
Hr h H White, Duperial SAIC, Buenos Aires Ur 1 W Vllliema, Norsk Hydro Ur 0 H J Willismu, UP Barry Dr 1 S Williamson
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Ur Peter Wright, P k. P Villon
Hr John York, Cverberg
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PREFACE ACKNOWLEDGEMENTS, SIGNIFICANT CHANGES AND COMMENTS
1) Since John Stafford's retirement from 2CI, I am pleased to say that he has been elected an Honorary Fellow of the Faculty of Occupational Medicine at the Royal College of Physicians, London.
2) I would like to thank Dr Paglialunga for all his patience and hard work in helping me to acquire the necessary facts which enabled me to place the recent Pansac ASL in the Register.
3) I would like to thank Dr Laundrie, General Tire and Rubber Company, Akron, Ohio, and Dr Dacey, Robert A Taft Laboratories, Cincinnati, for informing me of recent ASL cases.
4) I am grateful to Dr Contassot for sending me information about three new ASL cases which have occurred at the St Fons' Factory in Lyons, and also for the full account which he gave.
5) I should be very grateful if I could be kept up to date with the five ASL cases which I have placed in the Register, who are all still alive at this present time.
6) I would like to express my appreciation for all the help I have been given in carrying on the work of John Stafford by everybody who has sent me their helpful comments and communications.
7) On taking over the Register, I discussed with Dr John Stafford his present format. We both felt this would be the appropriate time to consider any worthwhile comments about it6 presentation, and also suggestions for any way it could be improved, in order to benefit future analysis.
B BENNETT 17 Jan 84
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Table Sequence
Belgium
Canada
Czechoslovakia
Prance
Cermany
Italy
Japan
Norway
Sweden
UK
USA
Yugoslavia
Incidence of Cases pa (Table I)
Distribution of Cases
by Country
(Table 2)
Pattern of Cases by
Factory
(Table 3)
Latency Periods (Table 4A)
Distribution of Latency Periods (Table 4B-4H)
Annual Geographical Incidence (Table 5)
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER ANGIOSARCOMA CASES (REVIEW DATE - 1 JANUARY 1984)
1 2-3 4 5-8 9-13 14 15 16 17 18-20 21-26 27 28
29
30
31 32-8
39
ASL Case Numbers by year of Death (Table 6)
AO
ASL Case Numbers by year of first exposure (Table 7)
41
Western Europe PVC Producers - Start-up Dates vs ASL Cases (Table 8)
42
USA PVC Producers - Start-up Dates vs ASL Cases (Table 9)
43-44
Canadian PVC Producers - Start-up Dates vs ASL Cases (Table 10)
45
East European PVC Producers - Start-up Dates vs ASL Cases (Table II)
46
Japanese PVC Producers - Start-up Dates vs ASL Cases (Table 12)
47
South & Central American PVC Producers - Start-Up Dates (Table 13)
48
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IMPERIAL CHEMICAL INDUSTRIES PLC
Page
PKTROCIIEHECALS AND PLASTICS DIVISION A
LIVER Anglosarcoiaa Ca*e* - (Review Date: t January 1964)
1I 1 ** 1 COUNTRY AND j REFERENCE | NO |BELGIUM | 01
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i i NAME OR t DATE OP J INITIALS I SIRTH |
4 COMPANY
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1 1 ACE AT 1 DIAGNOSIS 1
i i i i J 63 |
i i i i i i i t i i i i i t i i i i i t i i i i i i i i i i i i t i i t i i i i i
9
YEARS OK EXPOSURE TO
DIAGNOSIS
IS
10 YEARS OF EXPOSURE
17
t ii t
t i DATE OP | DEATH |
i
i i i 1t J29.06.76 |
i i i i t i t i i i i i i i i i t i i t i i i i i i i i i i i t t i j i i i i i i
i t i | HISTOLOGICAL 1 CONFIRMATION |
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1( ||
1 |
ESTLHATED I
| OTHER
l OTHER
EXPOSURE | OCCUPATION J
CAREER
| COMMENTS
LEVEL |
| HIGHLIGHTS i
11
i
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Nigh
11
1
|Autocleaner |Drl Her In * |Hepatic teat*
JI4 yra
|foundry
|ln Oct 1974
1938-1968 |
1(2 yra)
|were nuraal.
eapoaed to|Polyworker | Faroer
|Retired
200 ppa |3 yra
|< 15 yr)
1 Feb 1975
for 0 hra J
(Work in glen* JMuapftalleed
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and 1 certainly |
under 500 ppa
In 6 to 9*1
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| |
autoclave*\ 1966-1972 | ejtpoaerf toj
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8 hr* per |
<t.y in
|
25a3
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i i i t i i i i i i i i
Industry
i |Couplet* ICllnlcal and [career detail* [are Riven In |paper Uy |Hublet et a) |!n Arch. Bclg |Mcd* Sue.,
1 N y K- Med . I'lrjv. Med.
IU*. 11977 page*
autoclave*! 1972-1974 | expoued to| 50-200 ppa | In auto- | clave rouai 1974-100 |
PP 1 1975- 50 |
i i t i i i t i i
1601-622
i i i i i i i i
PP* RETIRED
1 |
1 Feb 19731
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IMPERIAL CIIEK CAL INDUSTRIES PLC PETROCHEMICALS AMD PLASTICS DIVISION
iviiuadi^ojj
. ;V LIVER Aagtosarcon* Cases - Review Date: 1 Jan 1904)
* All dates use UK aysten
Canada
DAT - MONTH - YEAR
Sheet l
** Data published In Journal of
Oec Med 1978 pages 3TB-340
*** Many of dates altered to fit NIOSJI 11/3/77 Hat
rage 2
ii
i
12
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11 iCUUNfHY AHU j NAME OR | DATE OF t
REFERENCE | INITIALS | B1RT1I l
NO i i
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1t 08 113.05.20 i
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1 1 1 COMPANY | FACTORY
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ii FIRST VC i DATE OF i ACE AT
EXPOSURE i DIACNOSIS i DIAGNOS15
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1961
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1973
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53
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YEARS OF i TEAKS OP | DATE OF
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DIACNOSIS t
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HISTOLOGICAL i ESTIMATED |
|
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|
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I* Paper by Or F DEI.OK HE In Annates d'Aiiwtunle pathologlque Paris, 1970 Vul 21 Ho 2 |>|*I05-| 14 clalua tills esse lied both a liepatona end ASL uluml tsneouel y.
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IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVES Angiosarcoma Cases - (Review Date: 1 Jan
DAY - MONTH ~ YEAR
Sheet 2
* All dates nee UK eyetea
Canada
** Data published in Journal of
Occ Med 1979 pages 339-340
*** Many of dates altered to fit ttfOSII 31/3/77 JUt
Page 3
23
COUNTRY AND REFERENCE NO
NAME OR INITIALS
DATE OF BIRTH
4 COMPANY
1516 1 7 1 e
11
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1 t FIRST VC | DATE OF 1 ACE AT
t FACTORY t EXPOSURE | UI ACNOS 1 s 1 DIAGNOSIS
11
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9
YEARS OF EXPOSURE TO
DIAGNOSIS
10
YEARS OF EXPOSURE
11
DATE OF DEATH
12
HISTOLOGICAL CONFIRMATION
13
ESTIMATED EXPOSURE
LEVEL
14 | OCCUPATION |
IS
OTHER CAREER HIGHLIGHTS
1 1 1 1 1 1
16
OTHER COMMENTS
CANADA IQ
!
I6.0S.I5
1953
1976
61
23
14 00.04.77
Yes
Reactor cleaner
Furnace op. Maintenance packaging
Ex-uiauker
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IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER Angloaarcuaa Cauey - (Review Date: I Jan 1904)
Page 4
n 15
COUNTRY AND REFERENCE NO
NAME 08 INITIALS
DATE UP BIRTH
CZECIIOSI.Q-
FACTORY
FIRST VC EXPOSURE
DATE OP DIAGNOSIS
ACE AT DIACNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
OTHER COMMENTS
Novaky
01.07.57 24.12.71
45
IB
16 24.12.73
Autoclave Cleaner
IAKC letter of 1-4-02 giving (letat11 fro* Prof A Dev Id of Centre liul Hygiene ami Occ dleeaaes*
1406.07.27 Stete Co
Novaky
01.11.50 27.11.64
37
15 26.11.64
Yea
Autoclave Cleener
IAKC letter of 1-4-02 gave aonewhat altered date* for thin caae. I have accepted the change* aInee the date* cave fruit Pruf A David of the Centre of Industrial Hygiene and Occupational Dleeaace, My datee coae originally froai K10SII.
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....:. v 4.
IMPERIAL CHEMICAL TNnUtSTRIES PLC PETROCHEMICALS AND PI.ASTICS DIVISION
LIVEN Angiosarcoma Cases - (Review Date:
Jan 1984)
France Slteet J
Page 5
COUNTRY AND reference: NO
NAME OK INITIALS
DAI'S OF BIRTH
FRANCE
15.04.24
\ 02 |S1H
t i i i i i !
01
\1 101.06. 11 | PCUJC i1 i1 i1 it i1 i1
!1
06.01.20
27.01.27
05
10 11 15
FACTORY
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
ACE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
16
OTHER COMMENTS
i lion
00.01.46 18.02.67
41
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29
Brignoud 19.10.49
26
Brignoud 18.01.65 11.05.76
16
19 19.02.67
High
Autoclave worker and cleauer 19 yra
Ref. Havler et a I Arch. Hal. Prof. | 10 n* 1 Nov 75 p 171-177
i 11 i 12 124.01 75 |
Yea
11
1
\ High |2 yra on [Italian
i i i (NIOSH no |
1 monomer
(origin
i i i comment) \
|10 yra on \
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1 (Ref. LG Runneton et Lai "Nouvelle \presue |medicalo' IS Nov 1977
n< JV> i
29 29.06.75
High
Polyworker 10 yrs aa autoclave cleaner Compounding 1 yra
VCM productloi 16 yra Italian POV Shcphc rd, Sawyer, Mason
Ref. Rely et al Arch. Hal. Prof. | 17 n*
6 June 71 p 551 -555
26 04.01.76
High
Monomer production worker 8 yra PVC 111tratIon 18 yra
13.05.76
High
Polyworker 11 yra
1)Thoracotomy Ref . P Cootie re
9th Feb 1976 coetui angiosarcoma
et al "Scndlne dee houpltuux 10 Seplembre
2)SclntIgraphy 1976
found ASL
Previously hud
1)Haemorrhage bone
from ASL
Ullg 1 UUdtCUlM "
4)Right
Al so
Hepatcctomy
Pi t I I'llUUiikI a t
al "La Hmivelt
Presue Hod I cal
7th July 1979
Page 2485
CMft 0 0 6 3 2 5
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IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER Angiosarcoma Canes - (Review Dale: I Jan 1904)
Prance Sheet 2
Vagi* 6
13
COUNTRY AND REFERENCE NO
NAME OR INITIALS
DATE OF BIRTH
14.04.14
1 07 |CIR
1 ) i i i \ UB |B
i i i i i i
11 126.04 27 | RP
ii ii ii ii it i1 101.04 34 t Snivay
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FIRST VC EXPOSURE
DATE OP DIAGNOSIS
ACE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OP EXPOSURE
DATE OP DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER
|
CAREER 1
HIGHLIGHTS |
___________L i
OTHER COMMENTS
i
Brignoud 0l.03.5fl
12.08.76
42
18
11.09.76 (N10SH say* 12.09.76)
(1956-1960) 2 yra filtration 10-11 yra puiyworker and works tab?
t |Thin man hud |AOL prior to (AS. Ann. de
{HhI. Prof. |July '77 |p 645 A 6. IA01, was found |In 1971 five
|yra bcfure
JASJ.
I
1 1i1
|St Auban 01.07 50 | After
i 49
J
26
ii
| death
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| NIOSH
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| 00.07.76 i
i
! 1 (Tavaux
i _i
j___
i1
1
i 23.05.57 | 03.12.75 1
42
! 1 I
19
ii
i
I
i
ii
t
!
i
ii
i
1
i
ii
i
1
i
it
t
1
i
ii
!
1
i
10.01.4S 26.04.76
63
1 11 1 22 (02.07 76 1
Yes
i 1 High
41
1
{Plant fure- {1972-6 admin (Died of
i i i (NIOSa au 1 i i i comment) 1
i ii
1
i ii
1
(man in (polymerlisatlon
i
{section In {St Auban
i i
|septIcaemla l Swal 1 1 Iver |lea I on fonud latter autopsy
i i ___L
_J _j
J
i 1i
11
1
i 19 {30.01.77 i
Yes
{ Moderate |6 yra packer]
i ii
i {6 autoclave {
l (Had been
|tunnel worker
i tt
i
|clnr
|
|previously
i ii
i it
i
|14 yrs
|
i (autoclave |
i i
i ii
i
Iworker
|
i
i ii
i J!
I
20 25.12.77
Very High Polymer
10 yra In
{Operated 4.76
1948-1966 isation
sulphuric
|fur removal u
Lesser
operator,
acid factury, {runout from
Exposure 1966-1976
autocleaaer autoclave maintenance
storekeeper 4 general services
| liver and Idled after f second faurgIiaI
(operation fur
jblLhi
|kit onclilal
|tJatula | paper by
| Dt Rely et al {in Archives d
|Haladea
|Pi ofensionala
IVol 40 No 6
{1979 piiges j 74J-J.
f*Istno<i r/qsTJB(j napsaotBO
j ^rnv-Oo
U7
tBiotpuf po;i OUJ `oooaog `A "ssoj
OATTj-oa^ojj oq qosfqng
iviLLiiactMuoo
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AMD PLASTICS DIVISION
LIVER AnglosarcoMa Cases - (Review Date: I Jan 1984)
France Sheet 1
Page 7
1J
1 I COUNTRY AND \ | REFERENCE \
NO
|Prance
ii 2 1 3I
11 11 NAME OH I DATE OP | INITIALS ) H1RTH |
ii JL
It il
1i 4 15 i6
Jt
COMPANY
1i 1 i FIRST VC ( FACTORY i EXPOSURE
ti
ji
ii
ii
i
7| 8
1 l DATE OP | AGE AT DIAGNOSIS | DIAGNOSIS
i i t t
Ul |VP 1) (t
17 LI
14 | HJ
3:
>
|24.05,IV | HP
(St Fons 1 00.12.56
ii
ti
ii
ii
it
ii
ii
ii
ii 1)5.02.12 | HP
ii JSt Pons i 00.01.4)
it
ii
ti
ti
ii
ii
it
ii
ii
ti
ii
ii
ii
ii
ii
ii
ti
ii
ii
ii
ii
ii
ii
i
ii
ii
ii
ii
ii
ii
ii
ii
ii
ii
116.03.14 l PCUK
| Brlgnoud t 09.02.49
ii
it
ii
ii
ii ii I19.0l.il 1 Solvay
i
!
ITavaux
i ! 1 23.09.61
11
tI
11
i1
11
il
11
tl
11
il
11
1
J\
1
11
i1
11
iI
11
1
105-04-24 | Chloe
JSt Fons
i
i Chlule
i
i i 4 Purserly i
i
i *e)
1
11
i
l I l i
I
1943
ii
1
ii
i7
10.01.73 12.08.73
00.05.79 26.06.79 00.07.31
(
i i t i i J
i i i i i i t i i i t i i 1 i t t |
i i i t |
i i i i i i 1
i i \ |
i
)
1 i
1
i
53 66
65 40
57
i ii
N i 10 i 11 i
12
i
13 1
l 1
15 \
16
t i\
1
i 1i YEARS OP t YEARS OF | DATE OP i IIISTOlACtCAL EX POSHHE TO i EXPOSURE | DEATH i CONFIRMATION
1
ESTIMATED 7
|
EXPOSURE | OCCUPATION |
OTHER CAREER
| OTHER ( COMMENTS
DIAGNOSIS i
ii
LEVEL i
} HIGHLIGHTS
i ii
i
i ii
i
i7
7
11
21
21 |10.01.78
Yea
High (Autoclave (10 yea lu
|Dled ot
i i7 i i1 i i1
(cleaner i i
|Meehan leal (engineering
(Industry
|pulmonary (embolism 5 |duye alter
i i1
i
(1946-1956
|urgery
i i1
37
i 31 m.it.78 1
Yea
High
7 1)961-1966
i i1 i i1 i i1
(polymer| teatJon (general
t i7
| pur|H>st
i t1
|worker
it
11946-1972
t i7
IVCM
i 11
)ayntheala
i 11
KlICI 6
i 11 i 17
|Acecyleue) |Foreman
i I1
1(agent
i 11 t 11
|tle maltrlse)! 11972
i 11
(retired
i 17
1
t 11
30
i 27 121.06.79 1
Yea
High
1 )Monomer
i 11
t 11
i 11
! 11
16
7 13 122.08.79 1
Yea
(production (and polymer)1 eat Ion (operator |Autocleaner (2 yra as cycle)Cigarette
I 11 l7 ( 17 I 1l
12 ym. (Auto(operator 19 yre.
(Mechanic.
I smoker out 11
|10 yra as
11974. Ill al I)
(enamel Ier In (of 1977 due t
(aanltary ware (Oosopliogeul
l 11
|Copulyuers (atauuf act ure (varices.
1 71
76 yra
(Surgical
t 17
1
JIntervention
I 11
1
125.05.79
1 11
7
1(right
l l1
38
l 36 I29.07.3t 1
Yea
l Very High 11963-1975
11975-1979
(lie pateciouy)
1 i1 I i1
1943-1975 (All typca ol 1 Maintenance
and
IJobe on
(work
7 i7
1 i1
1I
luletaltt--laanntacLure
ent 1/
It maintenance
1
1975-1979
(in VCH Poly 11`rucesn
<I
L
)
1 l
feucTStnoi "qstjEj mtsboibo >'!
5-i!U0 ^oiJ:q.Eiaj;-GrorpTif
^SV - OS ' oq 1 onj 0001103" -a ssog
Uf J8pIQ OA I q ,'4Q"-(I O^^.OOfqng
IHPURLAL CHEMICAL INDUSTRIES LIMITED
ivixiisaiilioy
PWSTICS UIV,S10N
LIVER Angloatrcona Cases - (Review Date: l Jan 1984)
ErAlice
Pane H
12
14 15
16
J* COUNTRK AND
REFERENCE NO
\
15
NAME OK INITIALS
DATE OR 61 Kill
01.01.37
FACTORY
Chloe Clilete (formerly
RP)
St Font
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
07.07.55 26.09.82
ACE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
27
YEARS OF EXPOSURE
17
DATE OF DEATH
H1ST0L0C1CAL CONFIRMATION
I ESTIMATED | EXPOSURE | OCCUPATION
LEVEL | ______________l_______________
1
High-20 yr ]Autoclave
Moderate (cleaner
7 yrt
(1955-1962
|autoclave
|operator
11962-1962
OTHER CAREER HIGHLIGHTS
OTHER COMMENTS
J C Contataot Letter of 5 10 |9B3
l
17
I 3.07.22
Ctiloe ChInle (Formerly
RP)
27.10.61 05.01.63
22.02.23
Chloe Ctil-le (Formerly
RF)
17.06.46 03.04.63
38 34 28 03.04.83
I Hlgh-33 yralPolynerisatModurate- |lan Process Low - 5 yra|Man
1 iHalntenance (Worker
1 lllealth 4 (Safety Agent
Retired Jan (979. I C Contaeeot
letter of 5 10 (963
High 23 yrt
1 Autoclave lCleaner 11946-1971 I
I 1
Other sectors of St Rona Factory 19711976
Retired 01.01.79 J C Coutasuot
letter of 5 10 1963
1 1
1 I
\
t t i i i i i i
9 0 0 VW3
ro
^^Tsinoq '`qsiJBj usts'bcit^O *
qjnu;j qJ iaqsiq i^totpnf qq^x
iLljV'OG ' ii
`ociouv'jg * a ssojj
ui j.^pj.0 OA7i.J3q.ojj oq. q.oefqng
iviiHaaiiNOo'
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS ANO PLASTICS DIVISION
LIVER Angloearcowa Case* - (Review Date: I Jau 19B4)
Cemany SheetI
Page 9
i
1
11
12
1
1 4t
1
\ COUNTHY AND 1 NAME OK
\ REFERENCE 1 INITIALS
| NO
3
DATE OP DIKftt
(GERMANY 1 I | 02
\ 03
1 1
i
1 1 1 1 1
i
1 1
00,00.30 Oil .00,31 00.00.30
| 04
1 n 3:
>
1
1
1
1
1 1
1 1
1
1 1
1
1
1
i
1
1
1
1 1
1
1
1
1
1
1
1
1
t
1
1
t
1
00.00.30
4 COMPANY Dynaalt Dynaatt Dynaalt
Hacker
1
1j
i
1
1
} FACTORY
1
1
1 1
1 ITroladorf 1 1 J Troladorf
1
1 Jlhelnfel|den
1
1
1
1 1
1
1 1
i
1
1
1
1
t
1
1
i 1 Burglliauaen
1
1
1
1
i
1
1
1
1
t
1
1
1
1
i
1
6 FIRST VC EXPOSURE 01.10.56 14.10.57 09.06.52
16.04.57
7I8
DATE OF | ACE AT DIACNOSIS 1 DIACNOSIS
19.09.68 (
38
25.09.70 *
39
00.03.73 |
43
26.11.74 f
44
o o ts
w
to
0
9 TEAKS OP EXPOSURE TO DIAGNOSIS
12 13
21
17
10 YEARS OP EXPOSURE
12 It 16
17
11 DATE OP
DEATH 25.01.69 14.12.71 10.10.73
25.11.74
1
12 1 13 1 14 1
1
1
HISTOLOCICAL | ESTIMATED 1
1
CONFIRMATION | EXPOSURE | OCCUPATION 1
1 LEVEL 1
1
15
OTHER CAREER HIGHLIGHTS
1
1
Ye. (NIOSH)
t
1 |polyworker
Yes (NIOSlH
1
1
IFolyworker
Yee (NIOSH)
1 t [Filling I pestIclde jaeroKo) cans| (with VC
1
1
t
1
t
1
1
1
1
t
1
1
1
1
Ye. (NIOSH)
11
1200-500 ppa]pal/worker & l1958 wad
(but high |tej>orary (autocleaner
(during | y r] autocleaiier |for ] yr
]autocleaner|
1
1
1
1
1
1 1
1 1 1 1 1 1
1 1 16
\ t | OTHER | COMMENTS
1
1
1 1
1
1
t
1
t
1
11
(Reported under I |non polyaer| ludtIon tworkera In LNIOSH Hat of tit.1.77. i Hi 1 a of coui*e| tla at r1et ly
\ correct.
1 However 1 f wonde r IwlietDur ttila
|nan lied lilgli
|eK|>ntiure to 1VCM In his lean filling luperatIon?
t 1 ICtInlcal (detallw In Jpaper by ICuket et al iVIrehowa Arelt tA Path 1976
I 177 |> 195 201 t
1
t
1 1 1 1 1 l 1 1
''tls-pj-Bj naxs-Boxso
qanoa xoTJ4at(I iBTOTpnf q^x
ZC0V-06 `oil `'oui *ouoiio3 -a ssog
UT asp-ip GAxq.a9q.0jj oq qo0fqng
iviijiaaiiHoo
IMPERIAL CHEMICAL ENIHJSTKIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER Angloaarco*a Casea - (Review Date: l Jan 1984)
Cenaauy Sheet 2
Page 10
COUNTRY AND REFERENCE NO
NAME OK INITIALS
DATE OP HIKTH
05
(HiOSH glvei aa Cauc 06)
00.00,36
(NlOSli gives sh Cane 05)
00.00.32
COMPANY
RUST VC
DATE OP
FACTORY EXPOSURE DIAGNOSIS
02.04.60 10.12.73
NaldshuC 16.12.62 00.00.75
Burg-
hausen
15.04.54 12.11.75
ACE AT DIAGNOSIS
41 49
YEARS OP EXPOSURE TO
DIAGNOSIS 13
13
10
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
05 16.12.74 Yea (NIOSII)
12 09.01.75
21
(M10SU aye 12)
13.II.75
n 14
1
ESTIMATED 1 EXPOSURE | OCCUPATION
LEVEL 1
_________1__________ I
1 1 |EG Cheie |eaya |"chealatry |laboratoriau {la the ITeclmn-
llogical Ifteaearch f Department **
1( NIOSII aay* laaalatant \factory |clienLa{ |which nay be |wrung
Itrunalatlon]
I 1 _J________________ 1 IPVC - Hunu|factore | shift Leader
1 I________________
I JPVC HaiiuIfacture and
|all work Mud autolcleaning
112 yr* | (1954-66) IForeuau Teel |1tev 8 yra 10967-1975)
OTHER CAREER HIGHLIGHTS
16
OTHER COMMENTS
Lionf Lriaed
Reported under tun-pulyaerieatiuu worker* in NIOSII Mat uf 31.1.77 and f.78. 1 don't think till* la a cniicct claaalficatlui by NIOSII. Hie man may have been Involved In VCH pol ytaeH nation in pilot plant or iii aain plant,
Uli.00.17 Dynaalt
Troladorl 19.07.54 06.04.75
58
20 25.12.75
Yea
i |folywurker
t
I
CMA 006330
^2Qu-q,h `Gil ^ { tic* t^O_0A]
'VVl
C^`',(ojrfJ^J 0-9Afqlnisgojf
____________ Og.
^i>i jff 5fmlii^o5'
IMPERIAL CIIEMI CAL INDUSTRIES FLO PETROCHEMICALS AND PLASTICS DIVISION
LIVER Angloaurcoaa Casco - (Review Date: t Jan 1984)
Ceraauy Sheet 3
Pago LI
\l * 41 1 country and J REFERENCE | NO J GERMANY 1 09
1 io M NltlSlI gives | as Case IJ)
! ii k< N10S1I gives k as Case 10)
1 >2
2
NAHA OR INITIALS
i 31
1 1 DATE 0F \ DIKTH |
i i i i
4 COMPANY
00.00.34 1 CWH
i i i i i i i 1
\ 1 00.00.16 | CUU
i i i i i 1 i i k 00.00.29 | Hacker
i i i 1 i i l 00.00.18 | Dyitaalt i i i t i i i i i t i i i
i i$ i i i k FACTORY
i
i i i k |Marl
i t i i * i i i i 1 I Marl
i i t i i k i i i (Burg1 hausen
i i i i i 1 JTrotsdorf
i i i i ( ( i i i i i i i
6 FIRST VC EXPOSURE 20.02.6k
01.01.61
10.10.55
00.00.61
7 DATE OP DIAGNOSIS 16.06.76
00.01.77
28.06.77
00.10.77
8 ACE AT DIAGNOSIS
41
40
47
39
9 YEARS OP EXPOSURE TO DIAGNOSIS
15
16
21
16
10 11
YEARS OP EXPOSURE
DATE OF OEATII
13 24.01.76
10 07.03.77 22 26.06.77
6 07.10.77
12 HISTOLOGICAL CONFIRMATION
Yes
Yes
Yes
Yes
i 13 1 14 1
1
1
ESTIMATEO 1
I
EXPOSURE | OCCUPATION |
LEVEL i
|
i
i
i
1 High peaks M2 yrs poly-
|worker Inel
|17X auto-
|clave
Icleanlng
IControl ruo|
H y* (
i i 1 High peaks 110 yrs jholyIworker inc) |17I auto| clave kcleanfng
High
i t i i 1 13 yrs auto(clave (cleaner
119 yre lilller
|operator
1
1 t JPVC Manu-
1 facture |Autoclave kworker Cor
1* ru 1 1 l 1 ( 1 1 1 1
15
OTHER CAREER K1GIIL1GUT5
ii 1 lb |
1 1 | OTHER
1 1 1
| COMMENTS 1
ti
it it ii
1l
MO/78
1
| (^ont Iraeil
1
(Average
|
|exposure first(
(9 yre 150 ppe.k
|occ 1000 ppa.| (Next 3 yrs av,|
| 75 pp*t. 1 ast. | (yr sv 35 pjxa k
kk
lk
|Average
|
(exposure flrel|
19 yrs 150 ppia, |
kcc 1000 pjwi.J
Jl.nut yr av
1
(73 |>|a. i:uil 11etter of 121.04.78
| ( k
11 ii ii 11
i( ii
ii
k1 11
ii ii ii
ii ii
ii ii
ii (i
!1 11 11
11
11 11
CMA 0 0 6 3 3 1
naTSKorBo jtM 0 q-0Ti5fra XETorpn^ q;,.T
I
COUNTRY AND REFERENCE HO
NAME OR INITIALS
DATE OR BIRTH
00.00.U
14
19 (NIOSH gives this as Case 13)
16
00.00.29 Wacker Dynawlt
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
Germany Sheet 4
Page
LIVER Anglasercowo Cases - (Review Date? | Jan 984)
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
ACE AT D1ACN0S1S
Ualdatvut 00.00.60 OB.04.7ft
63
Burghausen 19.10.53 09.10.78
49
Troiadorf
10.01.55
07.08.7ft (latbsch suspected ASL at Feb 1975 laparotuwy)
55
YEARS OF EXPOSURE TO
DIAGNOSIS IB
25 23
to 12
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
19.OS.7ft
Yes
Hot as Angtoearcowa In Ms letter of 21 12 8), Mr Frledel said this was a 'Platteneplthelkarzlnow Der Spelserohre" (a carcinoma of the oesophagus) not attrlbutable to VCH i not recognised as an Induwtrial disease
25 23.10.76
Yea
20 07.09.78
Yes
ASL and
Hepatocellular
Carcinoma
13 1 14 t
1i
ESTIMATED 1
t
EXPOSURE \ OCCUPATION i
LEVEL i
>
ii
ii
ii
ii
ii
ii
ti
ii
ti
it
ii
it
i
ii
ti
ii
ti
ii
ii
1i
1i
1i
lt
1i
1i
1i
1i
1i
1i
ti
T |Autoclave i
]cleaner and i
(worker.
i
|Drier
t
(operator. i
(Later shift i
(leader
i
ii
High
t (Autoclave (worker till (1964. (Leader aibd luster
t i i i i i
it
ii
ii
ii
ii
ii
k(
ii
ii
it
ii
15
OTHER CAREER HIGHLIGHTS
lU 1 t OTHER | COMMENTS
t i t i i IF U lent | letter of (30th June 19BD (enclosing data (f row (Hr H P Frledel |ot BG Cliemie IF W Best lletLer ol | 30t ti June I9B0 (enclosing dots If row III P Frledel of |BG Chowle (wJ thdrawlng (this case
i t i i i i i i i i | Angiosarcoma ]confIrwed 109/79. Sink (detail of tills (L also cases (9, (1, 15, 16 |4 17 given In (NKW Report fur 1 (97ft (Angiosarcoma (coni 1 rued, |fulI details |ot Illness (since March 11973 given In | NKU Hud Ilisp I Kc|> fur 1970. lomfcru.il (details given |tn "VC (Assuelated (Disease" by (Letbarli ami (Hsistel1 er K mi) (>7i.
CMA 0 0 6 3 3 2
inol '`qBTJBi neTSB3i3 ^
4-itiOj 3-3'i qsn'i L-TOTI^T
'ojouog *a ssoa
; ;. f>; "-II
ut
A^e-CJ
4.0
'!i!Vt*-
jj
04.
4-oaf^ng
^"V X Jj 11S Cl i ^ ^ ^ ^ _if. l's> k.`t ^''`-`i1
IHrtHIAI. CHEMICAL. IHUUSTHIES fl.C PETROCHEMICALS ANI) PLASTICS DIVISION
LIVER Angloaarcona Cases - (Review Date: t Jan 1984)
Geraany Slteet 1
Page 11
12
COUNTRY AND REFERENCE NO
NAHE OK INITIALS
DATK OF BIRTH
FACTORY
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
ACE AT DIAGNOSIS
YEARS OP EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE DF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
OTHER COMMENTS
GERMANY 17
(NIOSH gives as Case 15)
IB
21
00.00.37 Dynamic
Troladorf 01.11.61 14,08.7b
41
16
28.08.78
00.00.55 25.12.79
66
25.12.79
High
Autoclave worker
Autoclave Worker
Angloaarcoaa conf Iraetl. Annual report of tlte North Rhine Weet|ihal la Medical Inspectorate for 1978 pages 347-377 gives full Jetjlla. Vinyl chlor Ide rlleeaue diagnosed (12-02-71. Oesophageal varices. Rad I ologlcally cuiiflraed aero usteolysl a.
00.00.25 Dy natal t
Troladorf 18.10.54
54
25
18 22.02.80
Yea
High
Autoclave
Metaataslng
Worker
ASL
Dr Beache letter of 11-04-82 to Dr W C P AJsn
00.00.15 Dynnnlt
Troladorf 14.02.61 00.04.80
65
19
13 19.10.80
Yea
High
Autoclave
Haenanglo
Worker
Endothelioma
of liver with
Hetaataeea
Dr 8cache letter of 13-04-82 to Dr W G P Adana
00.00.13 Dynamic
Troladorf 01.01.62 00.09.79
66
17
13 19.06.80
Yaa
High
Autoclave
pronounced
Haenanglo
Worker end
clinical
Endothellofi
worked In
liver
of 1Iver with
drying shop
tyatoas)
Metastasee
Dr Be ache letter of 13-04-82 to Dr W G P Adua!
00.00.2] Dynanlt
Troladorf 15.10.61 17-09-80
18
11 06.12.81
Yea
High
Autoclave
ChargehanJ,
Dr Be ache
Hetastaslng
Worker
subsequently letter of
Pore nan
13-04-82 10
Dr V G P Adorn
9 0 0 VWO
f|iBi:sfnor[ "qsTJE^ nsTSot3 -vt
nog qoTjqsrq lETnTpnf
Z.28^-06 -on ^5v~
-a -53a
up J&pao QAi^u^c-.fj op posfqns
IVIiH&l'dl.ilfiOO'
IMPERIAL CHEHICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER Angiosarcoma Case* - {Review Date: 1 Jan 1984)
Should thin case be removed fro* the Hat? KIOSK have It ou their supplementary Hat relating to nun-polymer last ion worker* exposed to VCH.
JS 1/8/77
Page 14
l
----- 3---------------
COUNTRY AND REFERENCE NO
NAME OR INITIALS
DAT OP BIRTH
ITALY
01 (On NIOSN
aupplementary
net)
15.06.14 PANSAC
13 15
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
AGE AT DIAGNOSIS
TEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
OTHER COMMENTS
00.00.65 19.04.71
36
03 16.04.71
?Yea
PVC Hag extruder
Primary turnout may have been pericardium. Nut hornogeneoua wltli other cases.
1 03 |VG
i i i i
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13.1 1.29
Huntedlaon Porto Marghera
00.00.57
13.12.72
15
l1
11
1
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1
114.03 20 | Solvay
1 Ferrara | 00.01 53 } 10.07.75 1
35
|
22
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00.04.59
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ii i ii i ii
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1 ii
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1 00.00.67 1 07.03.63 i
46
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** See Kaltnnl hed d! lavuro 65 p445, 1974. Further details In letter from Dr Hunteuano of 1AKC on April 1st 1962.
Yea
*** Also see Maltnul and Kondlnekla In Acta Oncologies Vol I I960 pageu 35 - 49. (ICI has made a translation of this paper Into English and copies of the translation can he made available on request).
Polyworker
1 1 High
i i i i i
1 |Autocleaner |
IS yr (1*51-1 161) Autoclave
(operator
\
111 yr. (1*61-
im
i
1 1972-5 did | a variety ot]
Job.
|
Including l
PVC packing.|
1
***
12 yra Very High
5 yra Medium
4 yra Low
11 yr |Honome r
(Never cleaned (autoclaves.
(operator
(See paper by
1 120 yra -
(CHIAPP1NO et (al Med l.avoro
|Autoclave (Vol 6 <1982)
(operator 4 (PP 555-563
|otlter dutleal
(In euepens- i
|ion polymer -i
|1aatIon. ii
i
(Area Foreman!
k In name Depti
1 since 1975. i
a **
k Non-smoker.
| Consumed (little |a 1 cohol. (AOL.
No
1 |Medium-? Mil iil>
1 1 1 1
11 J bag extruderl
11967-1975 | (Commercial \
IDept 1976- |
|198)
k
1k
J |S Pag1 la|lunga telex ol |2 Aug 196)
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IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PLASTICS DIVISION
LIVER Angloearcuaa Caaee - (Review Date: I Jan 1904)
Page 15
COUNTRY AND REFERENCE NO
NAME OR INITIALS
DATE OP BIRTH
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
ACE AT DIAGNOSIS
TEARS OP EXPOSURE TO
DIAGNOSIS
10
YEARS OF EXPOSURE
II
DATE OF DEATH
12 n
X
HISTOLOGICAL ( ESTIMATED CONFIRMATION 1 EXPOSURE
I LEVEL
14 OCCUPATION
15
OTHER CAREER HIGHLIGHTS
16
OTHER COMMENTS
Toaojl Karl
Ql.Oti.22
NICbuL Toatsu
<ii
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Nagoya
00.04.*3 24.10.75
51
22
1 02 |SO
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a In It 1 a letter of let April 1982, Dr Hocitenano of I ARC asya Japanese Ministry of Labour give
Date of diagnosis - 21-08-74 Age of dlagnoala - 52 Yeare of expuaure - 22
24.10.75
i 1t i 13 |10.06.76 i i ii i ii i ii i ii i it
Yea
I
|PVC Aaaoc 13 yra auto
|aoys not
clave
(known.
cleaner
I* Japan
1964 -
|Tlaea
aaelgned to
|indicated different
|on 25.10.75 work since
(exposure* kiad 111
|often at
health
(3000 pp* up
(to 1974
*
I Not | | | |
1
known
|In polyoer- J
| laatlon work)
(Including |
(autoclave 1
(cleaning
|
11
Japan Tinea 25.10.75 A Japanese PVC Aaaoc letter of 31.03.78
1 JJapanese PVC |AuaocletIon (letter of (31.03.78 i i
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IMPERIAL CHEMICAL INDUSTRIES PLC PETKOCHEM(CALS AND PLASTICS DIVISION
LIVER Angiosarcoma Cases - (Review Date: 1 Jan 191*)
Page lb
l I2 |3| 4 |5|6
9 ( 10
13 14
IS
16
UNTRY AKU EPERENCE
NO
NAME OR INITIALS
DATE Of BIRTH
COMPANY
FACTORY
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
ACE AT DIAGNOSIS
YEARS OF | TEAKS OF EXPOSURE TO 1 EXPOSURE
DIAGNOSIS |
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
OTHER COMMENTS
I
\
01 | AH
23 2 3 I Norsk
Heroys
00.03.30 2l.I2.il
36
22
21 04.01.72
Yes
1 Hydro
Foreman 4 Autoclave supervisor
| | |
i i i i i i i i i i i i
J CuoHraed by |0r Hills[Evanuen of NN. |At APHK Mlg of 19 June 1976 iMr P Kaugne* [stated that AH [had been a liaeabcr of a [utart-np lean. |VCK 6 I'VC vote |na<Ee In same |l)tjlhll]j. Ibe |VCH was made [ f tint acetylene
vwo
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IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND FUSTICS 0 VISION
LIVER Anglosarcowa Case a - (Review Da
t Jau 1984)
Page l7
4t
COUNTRY AND
REFERENCE HO
NAME OR INITIALS
DATE OK RIKTtl
12 13
15
FIRST VC EXPOSURE
DATE OK DIAGNOSIS
AGE AT DIAGNOSIS
YEARS OK EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OK DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
SWEDEN 01
1023.06.27 Keaanurd Sunday all 14.08.51 20.10.70
43
19
20.10.70
Polyworker
16
OTHER COMMENTS
27.11.11 Keaanord Sund avail 00.01.45 00.06.72
61
27
27 16.08.72
High
VCH production
i 03 INC
1 l 04 jAL
i i t i i i i i i i t i i
ii
ii
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65
i
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116.11.L4 Keaanord Sundsvall 00.00.46 12.05.77 i
62
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31
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1 11
l 31 112.05.77 |
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i i Yea i High i i t i i i i i i i
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11 | Polyworker |
i
1 11946-1958
i
1 |
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|
| worker (12 1
lyre) t 1938-1
|1977 forewan|
1(19 yre)
t
11 t1 11 11 t1 1i t1
High 6 Yeare Low 10 Yeara
1964-1970 centrifuge operator 1970-1960 drier operator
Hr SJoeHn'e letter uf 28 March 1970 conftraut BL van a wuitower worker wfcio waa heavily exposed, p rolidbl y even wore bo than u iiureal reactor cleaner
( 1 1 1 | In first 12 |yre of leaptoywent had| |laeen heavl 1 y lexpoacd. In |1974. liver laLnuiaal lty land necrosis Idlugnoacd. |Data confirmed) 11n Dr D Byren |letter 18.8.7 J| |tu CEFIC 1
I.otter of 2nd Nov 1901 f rpa Dr David Hyren
* In hla letter of let April 1982. Dr Muntesano of IAHC aaya In Sweden's National Bourd of OS Health gives 20-02-70 as date ol diagnosis for Case 01 and 15-05-72 for Case 02.
CMA 0 0 6 3 3 7
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IMPERIAL CIIEMICAL INDUSTRIES PLC PETROCHEHlCAl-S AND PLASTICS DIVISION
LIVER Angiosarcoma Cases - (Review Date: 1 Jan 1984)
UR Sheet I
Page IN
COUNTRY AND REFERENCE HO
NAME OR INITIALS
DATE OP BIRTH
12 13 14
15
FACTORY
FIRST VC EXPOSURE
OATE OF DIAGNOSIS
AGE AT DIAGNOSIS
YEARS OP EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OP DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
16
OTHER COMMENTS
04.04.44 03.12.72
28 03.12.72
(Fox 4
(Fox 6
Collier
Colller
paper eaye
paper
23.12.72)
aaya
23.12.72)
03
02.06.37
Barry
00.02.66 00.12.74
37
09 3.5 24.12.74
23.06.20
26.04.S4 00.06.79
25 18 12.10.79
500 1944-7 VCM 1947-8 Drier 1946-61 Autoclave operator 1961-66 Drier
lee end Harry Lancet 29-06074 pages 1316-8
Dubinins f alir lc.it I tin
High
Autoclave cleaner
Em |ij 4ire Halted to 2.66 - 9.69
Medinahigh
54-5 gagging Plant 55-6 Drier Plant 56-58 Autoclave worker 58-61 CharguhonJ Drier
Plant 61-72 Forcaan
C 2/3 Plant
Pre-war llah packer 19)9-45 aray vehicle Maintenance 1945-54 fish packer
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IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AND PI AST ICS DIVISION
UR Sheet 2
Page (9
L1VEK AngJoeaicoma Cauea - (Review Date: 1 Jan 1984)
11
12
*3(4
1 11 l COUNTRY ANJ) l NAME OR | DATE OF |
| REFERENCE 1 INITIALS \ BIRTH J COMPANY
i '*(> 1 UX ( 05
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i | FIRST VC t DATE OF I AGE AT | YEARS OF i YEARS OF | DATE OF i HISTOLOGICAL * ESTIMATED t
(
| FACTORY | EXPOSURE i DIAGNOSIS | DIAGNOSIS | EXPOSURE TO | EXPOSURE | DEATH i CONFIRMATION 1 EXPOSURE * OCCUPATION |
OTHER CAREER
ii
i
|
| DIAGNOSIS i
ii
1 LEVEL t
| HIGHLIGHTS
i |Barry
ii
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| 08.01.51 t 00.10.79 |
65
t
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i ii i 21 |19.11.79 i
ii
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1i
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1
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17
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11960-1974
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|Motor Mechanic) (1948-1950
ii
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ii
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OTHER COMMENTS
y v iO
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09
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1 J07.05.25
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I
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS ANL> PLASTICS UIVISION
UK Sleet 3
LIVER Anglosarcoata Cases - (Review Date: I Jan 1964)
4 COMPANY BP
a1 5 i 6 i 7 i
!t
i
t FIRST VC i DATE OF i ACE AT
| FACTORY i EXPOSURE i DIAGNOSIS i DIAGNOSIS
ti
i
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1i
i
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58
li
i
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TEARS OF EXPOSURE TO
DIAGNOSIS
33
10 i " i
12 i 13
YEARS OF
ii DATE OF i HISTOLOGICAL i ESTIMATED
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DEATH i CONFIRMATION i EXPOSURE
i i LEVEL
i
29 24.02.63 i Yes
i Medina
ii
14 OCCUPATION Polyworker
IS 1
OTHER
1 |
CAREER
|
HIGHLIGHTS 1
2 yeara on
k |
Acrylonitrile |
Resin plant >
Aluo prior to
1950. 4 yearn
KAP
Maintenance.
1 years aotor
car paintshop.
2 years In
Craving Dock.
Page 20
16 OTHER COMMENTS
o 3; >
o
o 0u -b
o
CMA 0 0 A 3 4 1
"K-KM nns*om
3 *W<I IBJ>Ipnp tnvr
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IMPERIAL CHEMICAL INDUSTRIES PLC PETRUCHEMtCALS AMU ELASTICS DIVISION
LIVER taglourcMa Ciea - (bvltw Date: I Jm 1984)
*UK aytua of dataa DAY - MONTH - YEAR
USA Sheet 2
Page 22
<4*
COURTRY AMU REFERENCE HO
NAME OR INITIALS
DATE OF RUTH
COMPANY
10 Jk J2 13 14
FACTORY
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
ACE AT DIAGNOSIS
YEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
IS HIGHLIGHTS
OTHER COMMENTS
USA
09 Raymond 08.11.31 PC
2B.05.4i 01.09.74
49
29
24 1.09.IS
Ya*
2000 ppm
Celt Ie-
villa
Plugerf
10 16.08.13 Goodyear Niagara
12.06.9) 00.09.68
99
17
17 10.09.68
tel I kaa vfiM| figure* tt fltat eapoeure. J.oelev JI la Tinea 29.10.74,
2.1.79, 0.9.74
27.09.09 Goodyear Niagara
14.10.46 00.01.70
61
23
21 16.03.70
12 Francta A 17.11.18 Flreetoite Pottatova 11.07.49 02.09.69
90
20
19 02.09.69
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S Charle- 11.12.42 00.09.74
92
12
26 07.04.74
Edward
eton
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reactor op. Service op.
(not eleaner Bagger
- aeparate Dryer op.
crew cleaned Stripping op.
autoclave*) 3 yra prior
aervlce la
tyre plaut
Ref I letter of 26 April 1978 (rue Ruled J A Park to .1 T Scewe 11 of MCA
2000 ppn
Charleetoo Dally Hall 21 .7.79
14 Uublcue fibrJcatI no cue
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WFCKIM. CtKHICAL INDUSTRIES PLC PETROCHEMICALS MU PLASTICS U VISION
LIVES Angloearcoaa Cnum - (Review Da
I Jen 19**)
10 II
UK Spate* of detae DAY - MONTH - YEAR
12 I*
USA Sheet 3
n
COUMTUt AMU REVERENCE NO
NAME OR INITIALS
OATH or
a IHTII
FACTORY
PI VST VC UrOSIMttL
OATH OF UIACN0S1S
ACE AT I TEARS OP DIAGNOSIS ) EXPOSURE TO
| DIAGNOSIS
TEARS Of t DATE Of
EXPOSURE I DEATH
J
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
Page 2 I
1*
OTHER
COMMENTS
USA 16
17 IB
19 20
JJaaee | Howard
104.11.27 1 SPG
1
(Louie- | 08.05.50 00.00.69 t
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1
1 1 i1
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11
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11
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11
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11
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1 1 1 1 1 1
1 1 1
1 1 1 I 1 1
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of 2i.jo.rv
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IMPERIAL CHEMICAL 1WHIST8IMS PLC
petrochemicals and rustics division
LIVER Anglaaaccun* - (Review Ottit l Jen 1984)
*UK jreten of detee DAY - MONTH - YEAR
USA Sheet 4
rage 24
ii
1
I2
|J
1!
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1
COUNTRY AND I MAW OR | DATE OF
REFERENCE I INITIALS | BIRTH
NO 1
t
Ji
USA
1
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i 7 J 0 t 9 1 io 1 H
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DATE OF | ACE AT | YEARS OP I TEARS OF | UATE OF DIAGNOSIS | DIAGNOSIS | EXPOSURE TO | EXPOSURE | DEATH
| DIAGNOSIS
1 i
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(25)
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W 16.09.HI
fUr M N JuUiatin
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|la t lie
|caae Jencrlbed
Iby Dauneher
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|la Feb 1980
J Am J Medicine
Tee ii
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|Medium to (high for I2A yr.
1
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(letter of
|vtyl retain |labourer
418.8.)) to
|uolt end
tifiMi y 1J Steflord
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(Riven deleft*
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luult flret |renctor
| letter uf
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U6/2/I8
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lehlft
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lelilf 1 titl Uy INIOSM will
| ua
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CMA 00634-4
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'iviifiaaidioo
IHPEK1AL CHEMICAL INDUSTRIES LIMITED PLASTICS 01WIS10H
L1VCR ta|ioiirc4MU Cases - (Review Date: 1 Jen |984)
USA Sheet 8
*UK ijfitee of date PAY - MONTH - YEAR
Page 28
10 12 I)
16
COUNTRY AND
reference
NO
NAME OR INITIALS
OATS OP IIKTH
COMPANY
PACTORY
FIRST VC EXPOSURE
OATX OP DIAGNOSIS
C V Giroux 22-02-08
prlagfleld 15-10-51 Haas
00-07-79
US 11
S pergu.un OS-10-1J Jiir
SfG
LouU.lll. OS-09-54 11-05-SZ
US 34
Hr Ryrua
Loulavllla 1955
03-11-82
US 35 US 36
09-03-12
S Charie- 23-07-44 aton
18-07-81
27-OB-12
The Ceiutrel Ashtab
Tire aud
Ula
Ru bter Cu
11-06-56 21-08-83
ACE AT DIAGNOSIS
71
54
48
6l 50
YEARS OP EXPOSURE TO
DIAGNOSIS
YEARS OP EXPOSURE
DATE OP DEATU
28 14 17-05-80 (la PVC autoclave area)
IS IS Allv.
HISTOLOGICAL CQNPIRHATION
Aa autupay
lneed late cawaa of daath given a 'AagloaarcoM4
t ESTIMATED |
OTHER
EXPOSURE | OCCUPATION
LEVEL |
HIGHLIGHTS
1
I The death |1940-1951
certlflcate|Varioe* Joke
gave
Jia yoljaer
Hr CtrooH* |*anufocture
uaual
IRUTVAR
occupation 1LUSTKEX
aa "kettlej1951-1964
operator* IVarloua Joke la | In and
"cbeotcale |around PVC
induatry". |aetoclave*
11964-1975
IVarloua
tcleclcal
IJoba lu PVC
|polyeri*atloa
|facll Ity/
1 Rati red
101-03-75.
|Multiple IJube |Including |Poly (Operator 4 |Polycleancr
OTHER COMMENTS
I 11oforout lew Jgtvaa lo |letter of 24 |February I9B2 |f rua Dr (Walter C IRaraea of IHuuaeutu I Springfield to | Dr A Huaui of IHunaautu |Europe. I I
x I |Prof Taoburru IlcCler of |I2 Aug 1902 t |ltr H N Johneoi |letter of 12H Feh 198).
27 10 Alive Yea Lelooyooercoae
I Poly |Operator 4 |Autoclave ICleaoer 11955-65.
1965 left RPC |Ur H N Johuaoi to beem a lletter uf Clergyuan. 13 Nov 1982
laud 120 Feb 198).
14 18-07-83 Yea
I
High fro* |
1944 to
|
1955.
|
Hedlua fro| 1955-1958 [
I
27
27 Alive
Tea
Moderate 11956-56
|labourer
11956-57
|prod helper
11957-70
(operator
11970-75
lelecirlclau
|Dr Decry lletter of |5 Sept 190).
I
J___________
I 1R W InuuJrle lletter uf |W Sept 198)
lepotted at laedlcal | M-i y 1901. |Teallug
11975-preeeut |uperutur
1 Hay 1981
* ____
CMA 0 0 6 3 4 6
iM-oe -o ^-M--r-pir Wt
"r J0pi2^HW^4qsnya
1VI tl I{ 3 d fj^oo"
IMPERIAL CHEMICAL INDUSTRIES PLC PETROCHEMICALS AMO PLASTICS 01
LIVER Angiosarcoma Cases - (Review Da
1 Jan 1984)
Page 27
I
I
COUNTRY AN1) REFERENCE NO
NAME OK INITIALS
DATE OP RIKTH
YUGOSLAV1A
01
OS.04.14
Jugo VI nil
15.11.31 Jugo
Vinll
03 21.12.31 Jugo Vinll
U.Ob. 30
Jugo Vinll
Split Split
split
Split
10
12 13 14
15
FIRST VC EXPOSURE
OAT OP DIAGNOSIS
ACE AT DIAGNOSIS
TEAKS OP EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
16
OTHER COMMENTS
00.00.53 08.04.73
59
20
08.04.73
00.00.50 12.07.73
42
23
18 12.07.73
tee*
04.06.54 11.01.76
45
22
22 11.01.78
15.12.58 01.09.78
48
20
03.09.78
Yes
VCH Production
VCH Production
SARIC et al paper Knv Health Perspective Vol 17, pp 189-192 1976
Mn hls letter of 3 Oct 1978 . Dr Spirts* oE NIOSII changed the statue oE Case 02 tn VCH product ion employee. Dr Spirts* also notified * new Ca*e 01 also a VCH product Iom worker
Koee Kaminski letter of 19th June 1980 and IAKC letter of I April 1982
o
3:
CVZ900
CMA 0 0 6 3 4 8
TABLE 1
(Review Date - 1 Jan 1984)
Incidence of ASL Cases Per Annum
By date of death
1955 6
7
8 9 1960 1 2 3 4 5 6 7 8 9 1970 1 2 3 4 5 6 7 8 9 1980 1
2
3
1 0
1
0 0 0 1 1 0 2 0 0 1 5 3 2 3 5 7 6 11 11 9 10 5 10 4
1
4
Total
103
N.B. 1 Does not Include Italian 01 but does Include German 03.
2 The 1977 total Includes US case 24 which is a Cholanglosarcoma.
3 The 1982 total does not Include US 33 and 34 who are alive and F 15 who is alive 4 The 1983 total does not include US 36 and F 16, who are alive
Page 28
Distribution of ASL Cases by Country
USA W Germany Prance Canada UK Sweden Yugoslavia Italy Czechoslovakia Japan Belgium Norway
33 *** 21 ** 17 it-kit 10
8 5 **** 4 ***** 4* 2 2 1 1
TABLE 2
(Review Date - 1 Jan 1984)
Page 29
;^ C O K F n ) E IfT IA Lr Subject to P ro te c tiv e Orf.er In Ross 7 . Conoco , In c ,. Ko. 00-4837
14th J u d ic ia l D is tric t Court
..Calcasieu Parish# Lou is ia na
Total
108
* Omit ItOl - atypical case of PVC bag extruder. ** Includes GE03 aerosol can filler. *** Includes case US 24 which was diagnosed as Cholangiosarcotua & US 33, 34 and 36; and F 15 and 16 who are alive. **** Includes one monomer worker. ***** Includes two monomer workers,
i.e Western Europe North America Rest of World
.
57 43
8
CMA 0 0 6 3 4 9
Total 108
Pattern of ASL Cases by Factory
TABLE 3
(Review Date - 1 Jan 1984)
Page 30
(a) W Europe
Of the 57 cases in W Europe, 46 have occurred in clusters at 10 factories. Of the 21 German cases, 18 have occurred in clusters at 4 factories.
ASL Cases
Kemanord, Sundsvall PCUK, Brignoud Dynamit, Troisdorf Chloe Chimie (Formerly RP), St Fons Wacker, Burghausen CWH, Marl ICI, Hillhouse BP, Barry Solvay, Tavaux Lonza, Waldshut
5 5 10 8 4 2 2 6 2 2
46
NB: There are 31 pre 1962 PVC plants in W Europe; 18 of these have had ASL cases (Ref Table 8)
(b) N America
Of the 43 cases in N America, 37 have occurred at four factories out of a total of 49 factories - in N America 39 plants have not had ASL cases.
rj
Fi JL c* ri 0)0 O
T) O' u B1
Hi
ai 03 l2* -H
HH t>H ..1l-^p
tn {s'.
Vo
oa) C
wn
Pi
-H o
.
fn o
t't
PM O
oo
pi
fH
Pi
<ri PM
P) d)
O +* l
**H
o H 1 O
10
cd o
ri03 H i--t
2 wl"* u
to o pp>
ASL Cases
BFG, Shawinigan BFG, Louisville UCC, S Charleston Goodyear, Niagara
10 13 10
4
37
NB: There are 29 pre 1962 PVC plants in N America; 10 of these have had ASL cases (Ref Tables 9 & 10)
0 ? 0 0 VW3
(c) Rest of World
The 8 ASL cases are believed to be in 1 cluster of 4 and 2 clusters of 2 cases.
TABLE 4A
(Review Date - 1 Jan 1984)
Page 31
Latency Periods (Years from first Exposure to Diagnosis)
W Europe Belgium
No of Cases 1
Total Years 18
Average 18
France
17 438 25.76 *
Germany
21 385 18.3 *
Italy Norway Sweden
4 74 18.5 1 22 22 5 122 24.5
N America Rest of World
UK
US Canada
Cze clioslovakia
8 57
33 10 43
2
189 1248
835 204 1039
30
23.62 21 .89
25.30 * 20.4 * 24.16
15.0
Summary
Japan Yugoslavia
2
4 8
39 19.5
85 21.2 154 19.2
W Europe
57
1248
21.89
N America
43
1039
24.16
Rest of World
8 108
154 254T
19.2 22.60
* Of the countries with^> 10 cases, France and USA have average latency period above world average and Germany well below
, 9 0 0
Ut
DISTRIBUTION OF LATENCY PERIODS
TABLE 4B
(Review Date - 1 Jan 1984)
Page 32
0-9 yrs 10-14 yrs 15-19 yrs 20-24 yrs 25-29 yrs 30-34 yrs 35+ yrs
Total
Average Latency Period
Belgium Canada
1
1 11
1
1
1 11
1
1 Czechoslovakia 1
J
1
France Germany Italy Japan Norway Sweden UR USA
11
11
t1 |
11
1 j4 1l 11 j1 I1 i 11
11
I1 j1
11
11 j1 1 i1 t1 4 1i
Yugoslavia
i
1
i i
1i
TOTAL
i i I1 31
1
l|
1 11
J4 4I
j4
<1 i
11
i l4 i J i l1 2I i i i
11
i ii
1l i i ii
1
4I i1
9I 4
2I 1i
li lI i ii
2i
4 2|
i4 1|
i i
29
i i 1l 5|
1 1
1
2I j1
6* t 4i
2I j4
l| 1i
ii
4 i
1
l l1 71
i 4I
1
28
1 1 11 21
1 1
4 5t
11 21
1 1 11 1
i1
1
1 21
1
31
11 81
1 1
1
22
1 1 1 1
I
1 1 21 11 1 1
f 11
1 11 1
J 11
1 21
41
1 1 1
II II II i II 18 U1 4 |1 |4 ii 10 n 20.4
11 11
ii 2 ii 15.0
I4 11 3 II 17 If 25.76
u11 41 II 21 II 18.3
11 44 If 4 il 18.5 1i if 4 1 ii 2 ii 19.5 L4 i4 u1 4 ii l n 22 4 4 14 it 5 Ii 24.5
11 11
ii 8 ii 23.62
I 1 11 5 Ii 33 il 25.30
11 11
ii 4 ii 21.2 ii n
108 22.60
* Includes G 03 aerosol can filler
CMA 0 0 6 3 5
eisino-i '*qsT^J nsfsboi^D too ^omsxaj_^lP_ni
06 `OH "oal `OOOU" `AA SSES0U
10
(Review date 1 January 1984)
TABLE 4C
Page 33
LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE
MAX POSSIBLE I
YEAR OF
1
LATENCY PERIOD I FIRST EXPOSURE 1
LATENCY PERIOD
1 ARITHMETIC MEAN
1
1 OF LATENCY PERIODS 1
11
11
44
I 1939
1 38*
1
1
43
I 1940
1
1 244 - 34.86 1
42
I
1
1 37 ,21,37, 4l ***
17
1
41 1 2 1 32,38
1
1
40 1 3 1 38,14,32
1
1
1
4
1 28,11,24,20,24,34, 391
718 - 26.59 1
I 5 1 27,22,28,29
1 27
1
1 6 1 21,29,31,26,28,15,23,1
1
1 1 30,35*** 36 | 7 1 29.24,29.28 35 I 8 1 28,24,34
1 9 1 30,26,20
11 I1 |1 1 458 24.11 1
I 1950
1 26,22,31,19,23,14,33 1
19
1
I 1 1 19,28,17,28
|
1
31 1 2 1 21**,15
1
1
30 1 3 1 25,22,23,22,20 |
1
I
1
4
1 21,21,25,25,21,28***,|
1 22
| . 592
m
21.14
I
1
I
5
1 22,23,24,14,19,21,27T *
28
1
1
1 27***
|
1
1 6 1 21,12,27***
I
1
26 I 7 1 19,17,15,13,16 I
1
1 25
I 8 1 18,18,15,17,20 1
1
1 9 1 16,21
1 328 16.4 1
1 1960
1 13,18
1 20
1
I 1 1 15,16,16,16,19,18,12 1
21 1 2 1 13.18.17.12
I
1 1
20 I 3 1 16,17 1 4 1 16,17 I 5 1 11
11
1 102 = 14.57 1
17
1
1 6 19
1
1
16 | 7 1 16
I
1
15 1 8 1
11
19 1 1970
1 1
!1 1 I VIOLA
I11
11
11 1 2 1
10 1 3 1
1 41
I TOTAL
1 108
11
11
1 1 MALTONI
1 1 GOODRICH
1 2442 IB 22.61 1
1 108
1
* Cholangiosarcoma ** Aerosol can filler *** US33, 34 and 36; and F15 and 16 still alive.
-mi ""Tmn
PJST80061400,11/WPX7-2
CMA 006353
(Review date 1 January 1984)
Page 34
TABLE 4D
LATENCY PERIODS OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND GEOGRAPHICAL
*'
LOCATION
MAX POSSIBLE 1
YEAR OF
|
LATENCY PERIOD 1 FIRST EXPOSURE I
LATENCY PERIODS IN
WESTERN EUROPE 1
NORTH AMERICA
1 ROW
11
1
1
44 1
1939
1
1 38*
1
43 1
1940
1
1
1
42 1
1 I 37,41***
1 21,37
1
41 1
21
1 32,38
1
40 1
3 1 38
1 14,32
1
1 4 I 28
1 11,24,20,24,34,39
1
1 5 1 27
1 22,28,29
1
1
6 1 21,29,31,33
1 26,28,15,23,30,35*** 1
36 1
7 1 29
1 24,29,28
1
35 1
8 1 28,34
1 24
1
1 9 1 30,26
1 20
1
-
1
1950
I 26,22,31
1 19
1 23,14
1 1 1 19,28
1 17,28
1
31 1
2 1 21**
1 15
1
30 1
3 1 25,22
1 23
1 22,20
1
4 1 21,21,25,25
1 21,28***
1 22
1
5 I "22,23,24,27***
1 14,19,21,27***
1
1 6 1 21,12
1 27***
1
26 1
7 1 19,17,15,13
1
1 16
25 1 1
8 I 18,18 9 1 16,21
1 15 !
1 17,20 1
1
1960
1 13,18
1
1
1 1 1 15,16,16,16,19,18 1 12
1
21 1
2 I 13,18,17
1 12
1
20 1
3 1 16,17
1
1
1 4 1 16
1 17
1
1 5 1 11
1
1
1 6 19
1
1
16 1
7 1 16
1
1
15 1
81
1
1
1 91
1
1
1 VIOLA 1970 1
1 1
1 1
1
1 21
1
1
I | MALTONI 31
t
It
1 TOTAL
1 57
1 43
18
* Cholangiosarcoma ** Aerosol can filler *** US33, 34 and 36; and F15 and 16 still alive
PJST80061400,12/WFX7-2
CMrt 006354
(Review date 1 January 1984)
TABLE 4E
Page J5
PLANT
START UP DATE
LATENCY PERIODS OF ASL CASES
NO OF CASES
AVERAGE LATENCY PERIOD
11
1
| LOUISVILLE
1 1940? 1 12,14,15,19,19,20,24,27,28,28,28,29,29 1
11
| SHAWINIGAN 1 1941? 1 11,12,14,21,22,23,24,24,26,28
1 11
I S CHARLESTON 1 1939? 1 24,30,32,32,34,35,37,38,38,39
1
|1
I TROISDORF
1 1954 1 12,13,16,16,17,18,19,21,23,25
1
11
1
1
13 |
1
10 | |
10 | I
10 I
1
22.46 20.5 33.9 18
V^c0
a-rs-eoT.^ Jta t^o^J .^-ssoS
cuoo ^o9?^S
PJST80Q61400,13/WPX7-2
CMA 00635
(Review date 1 January 1984)
TABLE 4F
Page j'O
LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT
YEAR OF FIRST 1
!11
EXPOSURE
1 S CHARLESTON 1 LOUISVILLE 1 SHAWINIGAN I TROISDORF
1939
1 38
1
1
1
1940
1
111
1 1 37
I
1 21
1
2 1 32,38
I
!
1
3 1 32
I
1 14
1
4
1 24,34,39
| 20
1 11,24
1
51 6 1 30,35
1 28,29,27 I
1 22
1 26,28
1 1
71
1 29,28
1 24
1
81
1 24
1
1
91
111
1950
1
1 19
1
1
11
111
21
1 15
I
1
31
1
1 23
1
41
1 28
1
1 21,25
51
1 14,19
1
1 23
61
1 1 1 12
71
1 1 1 13
81
111
91
111
1960
1
111
11 21
1 1 12
I 12
1
1 16,16,19,18, 1 17
p-ramoi `qSTJ'Si
'3
-_______ __ t-rrrt-T J'inn
PJST80061400,14/WPX7-2
CMA 006356
(Review date 1 January X984)
TABLE 4G
Page 37
PLANT
START-UP DATE | LATENCY PERIOD OF ASL CASES
NO OF CASES
AVERAGE PERIOD
1
I SUNDSVALL | | BRIGNOUD
1
| ST FONS
1
1
1
1
1
1
1945 1950 1939
1
1 16,19,27,29,31
1
1 11,16,18,26,30
1
I 21,28,29,37,38,27,41,34
11
1 5 1 24.4 years
11
1 5 i 20.2
11
1 8 i 31.8S
1
I | I
| |
1
1 BARRY
1
1
11
| BURGHAUSEN I
1
1 NIAGARA
i I
11
1948 1933 1947
1
I 9,17,18,28,31,33
1
I 17,21,22,25
1 15,17,21,23 !
11 1 6 1 22,66
11
1 4 I 21,25
1
1 4 1 19 1!
1
I l I
I
1
11
1 SPLIT ! 1941
11
1
1 20,20,22,23
1
11
1 4 | 21.25
11
1
|
I
Q-rC-eOl^ ,, -,n tUV^X
,ancO ? ^r^^.oaC-^S
,,o*~o6 0i1
PJST80061400,15/WPX7-2
CMA 006357
(Review date 1 January 1984)
TABLE 4H
Page
LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT
YEAR OF
1
1 1 11
11
FIRST EXPOSURE | SUNDSVALL | BRIGNOUD 1 ST FONS 1 BARRY 1 BURGHAUSEN 1 NIAGARA 1 SPLIT
1939
1
1 1 11
11
1940
1
1 1 11
11
11
1
1 37 , 41 1
1
11
21
31
1 1 11
1
1 38
1
1
11 11
41
! 1 11
11
5 I 27*
1
1 11
11
6 1 31
1
1 29
1
1
1 15,23 1
7 I 29
81
1 1
1
1 28,34
1 1
1 1
11 11
91
1 26,30
1
11
11
1950
1
1
1 19
1 1
1 1 31,33 1
1
1 28
1
1
1 17
1 23*
1
21
1 1 11
11
31
1 1 1 1 25 1 1 20
41
1 1 1 1 21 1 1 22*
51
1
1 27
1
1 22
1 21
1
61
1
1 21
1
1
11
71
1
1
1 1 17
1
1
81
1 18
1
11
1 1 20
91
1 16
1
11
11
1960
1
1 1 11
11
11
1 1 11
11
21
t
1
1 18
1
11
31
1
1
1 17
1
11
4 1 16
1
! 11
1I
51
1 11
1
11
11
61
1 1 19 1
11
* Monomer workers
wn^Tnoi
CV-inOD 4 ASSv-Oo 'H
'V??*--TM SBOIBO
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JS/JH/DSO 16 25 January 1984 PJST80061400,16/WPX7-2
Cttft 006358
TABLE 5
(Review Date - 1 Jan 1984)
Page 39
Annual Incidence of ASL Cases (Date of Death) by Geographical Area
1955 7
1961
2
4 7
8
9 1970
1
2
3 4 5
6
7
8
9 1980
1
2
1983 TOTAL
1 i 1i j Western Europe | North America 1 Rest of World | Annual Total
i 1 t1
1
I1
{
11
1
I1
1
11
1
t1
i
t1
1
i1
t
11
1 I 1 I 1t 2
11
I
1
11
i
I5
i
15
11
t2
t
13
i1
11
t
12
|1
12
1
i3
l4
i1
1
15
i 1 14 1 3| 8
13
i2
(
-(
5
i 6 1 4 1 1 1 11
1 6 I 3 1 2 | 11
16
13
i
i9
|7
t2
i
1 i 10
t5
|
1 ~(5
1 6 t 4 1 - t 10
t 4 io t -t4
fo
11
1 nil to date f
l
13
i1
| nil to date |
3
(
55 * ** I
40**
f
8 t 103
* Includes G03 aerosol can filler but omits It 01 bag extruder
1 Cumulative |
( Total
| Key Events
I1
1 11
i2t
1
t
1 31 I4 t
1
(
1 61
I7 t
1
t
1 12
1 15 1 17 i 20
1 25 1 33 I 38 1 49 I 60
1 69 1 79 t 84 f 94 I 98 ) 99 1103
1
t
1 1
f t f
1
!
1
t
1
l
1
1
f
1
) t Viola
1 1
t Maltoni 1 Goodrich f
1
t
1
1 1 1 1 1
1
** Does not include US33, 34 and 36; and F 15 and 16. All still alive
<> s o - V
* O ? ^
C. "V-,
O
p-'is
V >'
X>:
(Review date 1 January 1984)
TABLE 6
Page
4 /* J
ASL CASE NUMBERS BY YEAR OF DEATH AND GEOGRAPHICAL LOCATIONS (EXCLUDING IT01)
1 KEY 1 1 EVENTS 1
1 WESTERN EUROPE
1 1 NORTH AMERICA
1 1 REST OF WORLD
1 1 1 1955
1 1 1 Cl
1 1 I1
1
16 17 18 19 1 1960
1 1 C2
! 1 1
1 I 1 1 1
t1 12 13 14
1 US8 1 C3 1 1 US5
1 1 1 1 Cz2
15
16
t7
18
19
1 Viola
1 1970
11
12
1Maltoni 1
3
I Goodrich 1
4
15
1 El
1 G1 1 Swl 1 G2 1 N1,Sw2,UK1,It2 1 G3** 1 G4.G5.UK3 1 F2,F3,G6,G7,G8,It3
1 1 1 1 C4,C5,US4,US7,US10 1 US12.US16 1 US11 1 C6.US2 1 C7 1 C8,US1,US3,US23 1 C9.US13 1 US6,US9,US18,US26
I 1
1 1 1 1 1 1 1 Yl,Y2,Czl 1 1 Japl
1 6 1 Bl,F4,F5,F6,F7,Sw3
1 US19,US20,US22,
1 Jap2,Y3
17 18 1 19 1 1980
1 F8,F9,G10,G11,G12,Sw4
1 CIO,US21,US24*
1
I F10,F11,G9,G13,G15
I US27.US28
1 Y4
1 G16.G17
1
I
I FI2,F13,UK4,UK5,G18
1
1
1 UK6, UK7,G19,Sw5,G20,G21 1 US17, US29, US30, US32
1 1 1 It4,F14,UK8,G22 12 1 3 1 UK09, It5, F17 1 Total I 55 ***
1 1 US31 1 US35 I 40***
1 1 1 18
1 t1
* Cholangiosarcoma ** Aerosol can filler *** Does not include US33, 34 and 36; and F15 and 16.
All still alive.
mreisinon;
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CMA 006360
(Review date 1 January 1984)
7TABLE
Page 4^
ASL CASE NUMBERS BY YEAR OF FIRST EXPOSURE AND GEOGRAPHICAL LOCATION (EXCLUDING IT01)
KEY | EVENTS 1
1
1 WESTERN EUROPE
1 , NORTH AMERICA
1 REST OF WORLD|
11
11
1 1939 1 1 40 1 1 1 1Frl1,Frl6***
I 2I I 3 1 Frl4 1 4 IUK1 1 5 1 Sw2 ! 6 IFrl,Fr3,Sw4 1 7 I Sw3 1 8 1Fr9, Frl7 1 9 IFrl2,Fr4 1 50 IFr7,N1,UK8,UK9 1 1 1Swl,UK5
| US24*
1 C3.US27
1 US13, US29
1 C2,US19
1 Cl ,C5,US5,US7,US28,US35 1 C4,US3,US9
1 C7,C9,US8,US11,US21,US31 1 C6,US22,US26
1 US1
1 US12
1 US 16 I US10, US32
|Y2, Cz2
1 2 |G3**
1 US4
1 3 1G15,It3
1 CIO
IJapl.Yl
1 4 IG7,G8,UK4,G19
1 US18.US33***
|Y3
1 5 1G11,G16,G18, Fr15*** ! US2.US17,US20,US34***
1 6 IFR10.G1 ' | 7 |Fr8,G4,It2,G2
| US36***
ICzl
1 8 IFr6,B1
1 US23
1 Jap2,Y4
1 9 I Fr2,It4
1 60 IG5.G13
1 1 IG9,G10,G12,G17,G20,G22 | C8
1 2 IG6,UK6,G21
1 US6
1 3 1Frl3, UK7 1 4 1 Sw5
1 5 I Fr5 1 6 1 UK3 1 7 1 It5 1 81 1 91 Viola | 70 I
1 US30
1
2
I Maltoni 1
31
11
1 Total I 57
1 1 1 43
1 1 18
11
1
I
* Cholangiosarcoma ** Aerosol can filler *** US33, 34 and 36; and Fr 15 and 16 are still alive.
PJST80061400,2/WPX7-2
jtr.ol
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CMA 006361
TABLE 8
WESTERN EUROPE PVC PRODUCERS - START-UP DATES vs ASL GASES (CMITTING G03)
STAKT-UP 1 COUNTRY NAFE I COMPANY NAME I
IDCATICN
I ASL CASE NUMBER 1
YEAR OF
YEAR 1931 1933 1938
1
IWest Germany IWest Germany 1 Italy
1
IBASF IWacker IMontecatini
1
ILudwigshafen IBurghausen |Acna
1 1
104,07,11,15
1
1 1st Exposure
1
157,54,55,53
1
1939 I France
I Rhone Poulenc ISt Fans
103,09,10,11,14, 146,48,56,41,43,
1940 1940 1945
11
lUnited Kingdom |ICI
lUnited KingdcmllCI
1 Sweden
IKananord
115,16,17
I Runcorn | Hi H house
1
101,04
1 Sundsvall( Stockvik) 101,02,03,04,05
155,41,48
1
144,54 151,45,47,46,64
I Switzerland ILonza
ISins
1946 1 France
1 Rhone-Poulenc IRousillon
1 101
1
146
1947 1 Italy
I Montedison
I Porto Marghera
102
157
1948 limited KingdomlBP Chan
IBarry
103,05,06,07,08,09166,51,62,63,50,50
IWest Germany IMls
IMarl
109,10
161,61
1949 1 Belgium 1950 I France
ISolvic IPuk
I Janeppe IBrignoud
101 138 102,04,05,06,12 159,49,65,58,49
1 France
IRhone-Poulenc I St Auban
107
150
I Holland I Norway
1 Stall I Norsk
IPemis IHerova
1 101
1
150
1951 I Italy
1 Montedison
I Brindisi
1
1
1952 I Italy 1953 I Austria
I France
1 Montedison IHalvic ISolvic
I Terri IHallein ITavaux
1 1
108,13
1
1
157,63
I Italy
ISolvic
I Ferrara
103
153
1 Spain
|Rio Rodano
limited Kingdom|BIP
IHemani 1 Aycliffe
1
I
1 1
IWest Germany IHoechst
IGendorf
118
155
1954 IWest Germany IDynamit
ITroisdorf
101,02,08,12,16, 156,57,54,61,55,61,
I 1955 I Spain 1956 I Spain
11
I Monsanto Iberia IMonzon
ICaiqsa
ISabinanigo
117,19,20,21,22
1 1
154,61,62,61 1
1
1 IHispavic
1958 IWest Germany ISolvay
1960 1 Italy
IS C Ravenna
ITorrelavega
IRtainberg I Ravenna
1
1
104
1
1
159
1960 IWest Germany ILonza
IWaldshut
106,13
162,60
1962 I Portugal 1965 1 France
I Italy
Idres
ICporto
1 Rhone-Poulenc IMontluccn
IPozzi
I Ferrardina
1 1 1
1 1
1
IWest Germany IWacker
I Cologne
1
1
1966 IWest Germany IHoechst
|Knapsack(Frankfurt) 105*
160
1967 I France
IAIO Chime
IBalan
1
1
1968 1969
1970
1971
I Spain
IRio Rodano
I Greece
|Esso Pappas
|Belgium
IBadiphil
limited KingdcmIVinatex
I Italy
IRumianca
1 Italy
1 SIR
limited Kingdom|ICI
I Italy
IS C Ravenna
1 Miranda de Ebro IDiavata Salonika IAntwerp IStaveley inapHarl Sardina 1 Porto Torres Sar I Runcorn 1 Ravenna
1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1
1 Spain 1 S*den
IHispavic IKananord
IMartorell 1Stenungsund
1 1
1
1
limited KingdomlBP Chan
IBaglan Bay
1
1
1972 I Finland I Holland
1976 1 France
I Pekana
ISvartback
IDS1
IBeek Limburg
ISoc Art D'vinyllMazingarbe
1 1 1
1 1 1
1977 1 Spain
1 Monsanto Iberia|Tarragona
1
1
* Laboratory worker in Research Department
**?ansac,Mira Venice, case not included, (It 05) due not knowing start up date of the Plant.
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C*A 0063^2
(Review date 1 January 1984)
Page
TABLE 9
USA PVC PRODUCERS - START-UP DATES vs ASL CASES
START-UP I COMPANY NAME YEAR 1 1939? |*UCC
1
1940? l*BFG
1946? 1947 1948
1
I |*UCC I Goodyear I Firestone
1 Uniroyal
1950 1952
1
1 Monsanto I Dow
1953 1954 1956
1 BFG I Diamond
1 General Tire I Air Products 1 Atlantic Refining 1 Borden
1957
1958 1960
1 Conoco 1 BFG I Great American 1 Plastics 1 Hooker 1 Pantasote I Atlantic Tubing I Tenneco 1 Keysor Century I BFG 1 Air Products
1
I Borden
1962 1963 1965 1966
1967
I Tenneco 1 Conoco 1 Stauffer I Conoco 1 Ethyl 1 Diamond I General Tire/Pantas 1 BFG 1 Stauffer 1 Allied
1968 1969
1
I Hooker 1 Firestone 1 BFG 1 Goodyear I Olin
1 (Formerly Conoco) 1971 1 Conoco
LOCATION
1 ASL CASE | YEAR OF
1 NUMBER
I 1st EXPOSURE
S Charleston
107,13,19,21,24,1 44,42,43,46,39,
127,28,29,31,35 | 41,44,42,46,44
Louisville
101,02,03,04,05,1 48 ,55 ,45 ,52,44 ,
106,09,16,17,22,1 62,45,50,55,47,
Texas City Niagara Falls Pottstown Painesville (closed 1975) Springfield Midland Avon Lake Deer Park Ashtabula Pensacola Brooklyn Leominster Hebronville Niagara Fitchburg
126,33,34
1
108,10,11,20
1 12
1 1
132
1
118 I 136
1 1 1 1 1
123
I 47,54,55
1
| 46,51,46.55 I 49
1 1
| 51
1
| 54 I | 56
1
1
1
1
1
| 58
1
Hicksville
1
Passaic Cranston Flemington NJ
1
1
130
Saugus, Cal
1
Watson, Cal
1
Calvert City
1
(closed March 1982)
1 1 1 1
| 59
1 1
! |
Illiopolis
1
Burlington NJ
I
Aberdeen, Miss
1
Long Beach, Cal 1
Assonet, Mass
1
Baton Rouge
1
Delaware City
1
Mt Pleasant W Va 1
Henry, 111
1
Delaware City
1
Painesville, 0
1
(sold to Robintech)
1 1
1 1 1 1
I
1
1 1 1
|
Burlington NJ Perryville
Pedrickton NJ Plaquemine Assonet, Mass
I
1 1 1 1
1 1 1 1 1
Oklahoma City
1 1
1
I
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CMA 006363
TABLE 9 (Continued)
Page 4
USA PVC PRODUCERS - START-UP DATES vs ASL CASES
|START-UP |
I YEAR 1 1972 | 1 1973 I
|
COMPANY NAME
Nat Starch Borden Robintech
1 1974 I Atlantic Tubing | Shintech
1 1975 | Certain-teed | Georgia Pacific | Tenneco
I 1979 I Firestone
1 LOCATION
1
I Meredosia, 111 1 Springfield I Painesville, 0 1 (sold to Georgia I Pacific who I converted to 1 polystyrene) 1 Cranston RI 1 Freeport, Tex I Lake Charles 1 Plaquemine, La I Pasadena, Tex 1 Plaquemine
I
1
| | | | I | | | | I | | |
ASL CASE NUMBER
1 YEAR OF
I
1 1st EXPOSURE I
I
1
!
1
1
1
1
1
1
1
1
1
1
* My databank has no information on UCC before 1946 or BFG before 1950
NB Some of the plants in this list were closed down, some have changed ownership over the years
liTtr-TI-GA Tl9tS'BOT1B0
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PJST80061400,5/WPX7-2
CMA 006364
(Review date 1 January 1984)
TABLE 10
Page 45
CANADIAN PVC PRODUCERS - START-UP DATES vs ASL CASES
1 START-UP| I YEAR |
COMPANY NAME
| LOCATION
1
1 ASL CASE I NUMBER
1 YEAR OF 1 1st EXPOSURE
11
1 1943 1 Goodrich
1(1941?) |
1
I Shawinigan
1
11
101,02,03,04,05 144 ,43,41,45,44, 106,07,08,09,10 147 ,46,61,46,53
11
1 11
11
1 1951 1 Monsanto*
1
I La Salle
1
!
1 1
11
1 11
11
1 1957 1 Goodrich
1
I Welland
1 1
1 1
11
1 11
11
! 1966 1 Esso
1
I Sarnia
1 1
1
I
11
1 11
11
11
1 1979 1 Diamond Shamrock Alb I Fort Saskatchewan 1
1 1
11
1 11
* Terminated 1975
tr.oT. euat s
-C& ut j-9
V-*l 1
aofeO
,3-^ ?:-5S3
39 5ayf^S
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-
PJST80061400,6/WPX7-2
CHA 00636
(Review date 1 January 1984)
TABLE 11
Page 45
EASTERN BLOC PVC FACTORIES - START-UP DATES vs ASL CASES
I START-UP | COUNTRY NAME 1 COMPANY NAME
I YEAR 1
!
IPre 1939 lEast Germany |State Company
1 1941 |Russia
|State Comps
I 1950 |Yugoslavia
1Jugo Vinil
I 1951 |Czechoslovakia |State Comps
1 1955 lEast Germany 1 State Comps
1 1956 |Rumania
1 State Comps
1 1957 |Poland
|State Comps
|Rumania
|State Comps
1
I 1958 |Rumania I 1959 I Hungary 1 1961 1 Rumania 1 1963 I Yugoslavia 1 1965 I Bulgaria 1 1967 1 Poland 1 1969 |Russia I 1970 |Rumania
1
I State Comps 1 State Comps |State Comps 1 Ohis 1 State Comps I State Comps I State Comps |State Comps
1 Russia
|State Comps
I 1972 |Yugoslavia
1Vinilplastika
1 1975 I Czechoslovakia 1 State Comps
I Russia
1 State Comps
I 1976 I Yugoslavia
1 Hip
' 1977 1 Rumania
1 State Comps
| LOCATION
1
ISchopau I Vladimir et al 1 Split INovaky |Bitterfeldt IIcechim lOsweicim (Dwory) |Tirnaveni |Turda |Risnov IBerente Borsod |Borzesti I Skopje |Varna ITarnow I Djerjinsk IRimnicu Vilcea I Volgograd 1 Zadar |Neratovice IKalush Area |Pancevo |Rimnicu Vilcea
I ASL CASE 1 NUMBER
1 1
101,02,03,04
101,02 1 1 1 1 1 1 1 1 1 1 1
I
1 1 1 1 1 1 1
1 YEAR OF 1 1st Exposure
1 1
153,50,54,48 157,50
1 1 1 1 1 1 1 1 1 1 1 1 1 1
I
1 1 1 1
j *1
I.7.& - 06 -- `a
***?$%
"" Vi
pjST80061400,7/WPX7-
CMA 006366
(Review date 1 January 1984)
Page o
TABLE 12
JAPANESE PVC PRODUCERS - START-UP DATES vs ASL CASES
START-UP I
COMPANY NAME
YEAR
1950 | Chisso Corp
I Kanegafuchi Kag
I Tekkosha
1951 I Mitsui Toatsu
1952 1 Mitsubishi Mon
I Sumitomo Kag
1951 1 Denki Kagaku
1 Nippon Zeon
I Toa Gosei
1955 I Ryo-Nichi
1956 I Nippon Zeon
I Nisshin Kagaku
1957 1 Kureha Kasei
1 Shinetsu Kag
1960 1 Denki Kagaku
I Kanegafuchi Kag
1964 I Chisso Corp
1966 I Tokuyama Seksui
1967 1 San Arrow Kagak
I Sumitomo Kag
1968 I Ryo-Nichi
I Shinetsu Kag
1970 1 Chisso Corp
1 Denki Kagaku
I Kanegafuchi Kag
| Kawasaki Yuki
I Mitsui Toatsu
I Nissan Kagaku
1 Shinetsu Kag
1971 I Tekkosha
1973 1 Asahi Glass
1974 | Toyo Soda
1975 1977
I Central Kagaku | Toyo Soda I Unknown
| LOCATION
1
| Minamata | Osaka 1 Sakata 1 Nagoya | Yokkaichi I Kikumoto | Shibukawa | Kambara I Tckushima | Uozu I Takoaka | Takeo ! Nishiki | Naoetsu 1 Ohmi I Takasago | Chiba | Tokuyama | Tokuyama 1 Chiba 1 Mizushima | Tokuyama | Mizushima I Goi (Chiba) 1 Kashima | Kawas aki | Sakai | Chiba 1 Kashima | Yokkaichi I Hayatsuki | Sakata I Yokkaishi | Kawas aki 1 Yokkaichi ! Kashima
| ASL CASE 1 NUMBER
1 1 1
1 01, 02
1 1 1
!
1 1 1 1
I
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 YEAR OF 1 1st EXPOSURE !
1 1
1 53, 58
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 1
I
1 1
T s . Z T
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PJST80061400,8/WPX7-2
CMA 006367
(Review date 1 January 1984)
Page 45
TABLE 13
SOUTH AND CENTRAL AMERICAN PVC PRODUCERS
I START-UP 1 1 YEAR 1 I 1953 1 1 1954 1 1 1955 1 1 1956 1 1 1960 1
1
1 1961 1 1 1965 1
1
1 1966 1 I 1967 1 1 1968 1 1 1970 1
1
I 1971 1 1 1975 I 1 1976 1 1 1977 1 1 1978 1
1
1
I 1979 1
COMPANY NAME
Monsanto Mexica Policyd Geon Do Brazil Elchlor Electrochlor Viplastic Indupa SOC Paramanga PET Columbiana Carburo De Col Plasticos Omega Primex Policasa Petro Dow Polimeros Mex Rico Chemicals Petroplas Indust Resistoc Huls Brasil Polychem Policyd PET Camacari
1 LOCATION
1
1
1 Lecheria (Mexico)
I Mexico City (Mexico)
1 1 1
1 Sao Paulo (Brazil)
1
I Sao Caetano (Brazil)
1
ICapitan Bermudez(Argentina)|
I Mendoz (Argentina)
1
1 Cinco Saltos (Argentina) 1
1 Pararaonga (Peru)
1
1 Cartagena (Colombia)
1
1 Medellin (Colombia)
1
1 Mexico
1
1 Puebla (Mexico)
1
i Managua (Nicaragua)
1
1 Conception (Chile)
1
1 St Martin Puebla (Mexico) 1
I Guyanilla (Puerto Rico) 1
1 EL Tablazo (Venezuela)
1
I Tlazcala (Mexico)
1
1 Cubato (Brazil)
1
I El Salvador
1
1 Coatzacoalcos (Mexico)
1
1 Camacari Bahia (Brazil) 1
ASL CASE NUMBER
1 YEAR OF
I
1 1st EXPOSURE |
1
1
1
1
1
1
1
1
I
1
1
1
1
1
I
1
1
I
1
1
1
1
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Live.- Angiosarcoma Cages
Cirsulation
Dr A Sosa Adana, Air Products Dr ? V Anderson, Hilton Dr I M M 3agshaw, Norsk Hydro Dr W C Sames Jr, Monsanto, USA Dr John J 3arr, Air Products Dr 3 3arrat, A.3.C.3.P. Dr Peter Barter, 3MA3 Dr M 3enech, Napntachimie Dr 3 Bennett, ICI Hillhouse Dr P 3ertazzi, Milan University Dr Beaehe, Dynamit Nobel, Troiadorf Dr C 3i3hop, 3MAS Dr D Bryson, Agricultural Div'n, ICI Mr David Burgess, ICI Americas Dr David Byren, Kemanord Dr J I Carter, 3MAS Mr C Celia, Hnichem Polimeri Mr M Chance, '/CM Technical Manager, Mond Mr P G Claus, APM3 Mr H Clayton, Norsk Hydro Dr J C Contas30t, Chios Chimie, St Pons Mr J 3 Davies, Everberg (2) Dr De Sloover, Solvay Sir Hichard Doll, Harden, Breen College, Oxford Mr S Dupont, AFME Mr H Emminger, 7K1 Dr V Srnat, Nurnherg Dr H Falk, CDC Atlanta Dr D M Ferguson, ICI Americas Dr H ? Fnedel, Heidelberg Prof 1 Oclberg, Durnaa, North Carolina, ISA Dr 3 S Goaztonyi Jr, Tenneco Chemicals, Saddle Brook (NJ) Dr Halter D Harris, Uniroyal Inc Dr Donald W Hillman, Diamond Shamrock Dr Sobert K Hinderer. BF Goodrich, Cleveland Mr J Hodgson, DMAS Dr H A Hogg, Imperial Oil Ltd, Canada Dr J K Howard, Wellington, New Zealand Dr N F Humphry, Melbourne, Auatralia Mr J Jauvert, Chloe Chimie, Paris Mr 3 3 Jervis, Millbank Dr M N Jorxson, BF Goodrich Dr Bruce Karrh, Dupont Dr 3 A Kruager, BF Goodrich Dr J P Laloine. Solvay Dr 3 H launorte, Aicron, Ohio Mr J lawrenee, SPI Dr J I Lae, Victoria Hospital, Blackpool Prof H K Laibach, University of Bonn Dr G Leviaue, CDF Chimie, AZF Dr D A Levison, St. Bartholomew's Hospital, Iondon Dr P Lewis, CIA Mr Lolivier, Solvay Dr J Lusaato, Atoohem Prof 3 N M MacSween, Heatern Infirmary, Glasgow Dr J M Maillard, Luzern, Switzerland
Prof C Maltoni, Bologna Prof Lo Martire, Medil-Anic-S, Milan Dr 3 Mattiuasi, Montedison Mr D Middleton, Norsk Hydro Mr Mokka, Nsste Oy Dr 3 Montesano, larc, Lyons Dr A A Motti, Dupenal SAIC, Buenos Aires
Dr A Munn, Monsanto, Brussels Mr M Munoz Mouton, 3io Bodano Mr S Nakamura, Japanese FVC Association Mr H G Olson, Louisiana Dr J J O'Sullivan, ICI Mond Dr 3 Owen, TUC
Dr G M Paddle, Central Medical Group, ICI Dr S Paglialunga, Montediaon Dr Hans Popper, Mount Sinai Medical Centre Dr J Poaaberg, Hacker Dr A M Puech, Atochem Dr J Purdham, Canadian Centre for OHS Dr J Sambaud, 3P Hecherohes Mr ? 3angr.ee, Norsk Hydro Dr P Hichard, Shone Poulenc Dr J 3uty, Atochem Dr J Salg, Niosh, Cincinnati Dr 3 Saracoi, Xarc, Lyons Dr M L Scheffers, DSM/CVMD, Holland Dr David Seronne, Diamond Shamrock Dr J Sigrist, Shell Chimie Dr Paul M Smith, Llandough Hospital Dr 3 Spirtaa, NC1/NIH Bethesda Dr Carol Stack, CMA Washington Dr J Stafford, UK Mr Stahneckar, BASF
Prof C 3 Tamburro, University of Louisville Dr Gary Ter Saar, Ethyl Corporation Dr B Terwieach, CWH
Dr Gilles Theriault, McGill University Prof Dr Thiess, BASF Dr 2 Thiis Svenaen, Norsk Hydro Dr H Tordoir, Shall Dr T 3 Torkelson, Dow Cr 3 J Van der Merws, Saaolburg, South Africa Mr J 3 Wallace, Zaao Chemical, Sarnia, Canada Mr H Waltemate, BF Goodrich, Cleveland Mr S 0 HeJdling, Kemanord Dr D J Wheeler, ICI Hillhouae Mr 3 N 'Wheeler, UCC Dr J whiaton, ICI Hillhouae
Mr K 3 'White, Duperial SAIC, Buenos Aires Dr D M J Williams, 3P 3arry Dr K S Williamson, Central Madical Group, ICI
Prof B Wilson, Harvard University Dr A P Wright, ? & ? Division, Wilton Mr John York, Everberg
BB
iFroo : Dr 3 Bennett, Meoical Department, Imperial Chemical Industries ?LC, Hillhouss Site, FO Box A, Thomton-Cleveleys, Blsokpool Fi; U^D, United Kingdom )
CMA 006369
PREFACE
ACKNOWLEDGEMENTS, SIGNIFICANT CHANGES AND COMMENTS
1. The new cases in the Register are the following : Belgium 02 UK 10 USA 3? USA 38
2. It should be noted that there are corrections from the previous Register against the following cases :
France UK USA
16 07 1^, 15,
55
3- I would like to thank John Barr for the Plant corrections that are in that Section.
4. I would like to thank Dr. De Sloover, Dr. D. M. J. Williams and Dr. M. N. Johnson, together with Mr. John Barr for informing me of new cases.
5. For the case corrections, I would like to thank Dr. J. C. Contassot, Dr. D. M. J. Williams and Dr. M. N. Johnson.
6. I would especially like to thank Dr. Joyce A Salg for the great deal of effort which she put into clarifying USA 14 and 13, which had previously been documented as dubious fabrication cases.
7. I should be very grateful if all the recipients of the Register could continue to keep me totally informed of any n w cases or, if they should hear of other Companies who have acquired a case of ASL, it would be much appreciated if I could be informed by the appropriate person.
8. With reference to the Register format, I will be continually trying to improve it.
B BENNETT 14 Jan 1985
o
3:
o o
O'
w 'J o
CMA 0 0 6 3 7 1
Index
Table Sequence
Belgium
Canada
Czechoslovakia
Prance
Germany
Italy
Japan
Norway
Sweden
UK
USA
Yugoslavia
Incident: of Cases pa (Table 1)
Distribution of Cases
by Country
(Table 2)
Pattern of Cases by
Factory
(Table 3)
Latency Periods (Table 4A)
Distribution of Latency Periods (Table 4B-4H)
Annual Geographical Incidence (Table 5)
PETROCHEMICALS AND PLASTICS DIVISION LIVER ANGIOSARCOMA CASES (REVIEW DATE - 1 JANUARY 1985)
1
2-3 4 5-8 9-13 14 15 16 17 18-20 21-27 28 29
30
31
32 33-39
40
ASL Case Numbers by year of Death (Table 6)
ASL Case Numbers by year of first exposure (Table 7)
Western Europe PVC Producers - Start-up Dates vs ASL Cases (Table 8)
USA PVC Producers - Start-up Datea vs ASL Cases (Table 9)
Canadian PVC Producers - Start-up Dates vs ASL Cases (Table 10)
East European PVC Producers -- Start-up Dates vs ASL Cases (Table 11)
Japanese PVC Producers - Start-up Dates vs ASL Cases (Table 12)
South & Central American PVC Producers - Start-Up Dates (Table 13)
41 42 43 44-45 46 47 48 49
Ca7na,,. Ciai
^0-40^
Casieu p . --iiriQt
PaMSh- Io8?a"f
iMItHLU CIM-HHAl. JNIHIS JMJKS HC KMmKiio.MiiiM.s and plashes division
LIVER Anjiioaurcuifca Cjae* - (Review Oetei ! January I9D5)
CUUNJHY AND KfelKlHSHCK
NUiK OR INITIALS
OATS Ufc ai mu
h
if us? vc SKKOSUt*
DATA Of DIAGNOSIS
AC AT DIAGNOSIS
YEARS OK KIKOSUKN TO
Di AGMOSJS
--
yrars or KIHtSUKK
OATK UK IIKANi
Salvay
iu*|>| 00.07*58
18 17 2V.06.76
9 0 0 VW3
I----29 09.4u Solvwy
Jnappe 20,06.62
*9 I?
2*. |l SI
-1-.. M
__________1______
I
n 1 *4 J
15
1
*6
(I t1
|
T
1 CSTIHATMl
|
1 r.xrasoitr. | OCCUPATION i
imitk CAKSftK
f 1
| OTiitM j CHHMKNl'S
t UVKI
| ill OH LIGHTS
1 1
J1. _
1 f
| 1
1
t
1 itUii lAutocleaner (Driller In a jliepat 1 c tceta
1
|14 yra
|fouudry
jin Oct 1974
1950-1960
Id ft.)
|wre m* total.
1 tiyuihii) to|Kolyworker (Tamer
|Xcl1 red
t 200 ppw 11 yr a
J(IS yr.)
|Keb 1975
t fur 0 lira
|tfork In glaan Jiloepltel lead
per day
|lod* A ckewl- (Hay 1976
| *ud
|cai Induatry
1 Certainly
(Conjilete
under
(Clinical and
1 SOI! [1)1*
|ca1ee r Jet a lie
1 In 6 to 1 9mi
|re alven In a Jpaper by
autnclavewl 19(8-1972
(Hublel et el jin ArU*. 0elg.
1 ttspoeed to| i 50-200 ppii| t 8 lira per
day in 1 25a*
autoclevee|
1 1972-1974 ( expoaed tu
( SO-200 ppn
(Med. Sac., (lly*. Had. lTrev. Med. it.*-
|1977 pe*e (601-622
| tn muJ clave ruuie I'WPioo
I W | 1975- 5U
) 41* | KT1*I!I> | l r*l> 1415
08.62 03.63
01.by 10. ?l 3 200 yfit 8 ti./0jr
u4.63 12.66
^ 200
Aulotleaner 5 ym S utlia Operator 1 yrn 9wtle.
Klreweci 10.71 -
ulnre
III dlftu July 79; 11*01 b(-ic pain 07. 79*
llepat 10 teat* altered 10.79 Koal[Ive eclrngtepliy 11.79. Ilepa -
tcctouy 02.80. I'Deuotliei npy . infernalion given li*
letter 12 Now I9H4 fro*.
_____L.
jDr Sluove*^
C OiJJ? T T} m -y-
Ject to P'-vw "T'-
JlO3S5SS y7,
Pn * 3-OOt iV,, r. n Conoco, jn,. 'f_ Ordop jn
C^oasi^u
o.
p^-zf'lc.t '~483r, ourt
I, ouif Lna
lllrtHf.11. I'MHilCAI. INOUhltllrS VIA'. Yfc fklHJtlKHICAl.S AWJ HASrifS DIVISION
LIVER Angloaenoaa Ceeee - (Review Dates l Jen 1D0S)
L'^iwiU SI.cot I
ra*e x
CMA 006373
<?, i -2_2j~ f D r; W'ieccoto'i,^i!tn I-U
24th*
i_rlle
v Qjrio
Jn
Cain Jtidlcial CuTti
' y90--4, 037
aIoasle PariS ?Ct Co^t
' iouisiana
iMl'KHIAJ i lH-KICAI. IHPlISJKJFS KL.C FKYROCmHJCAl.S ANN FI.ASTI CS ill VISION
t.lVRK Angloearcuaa Caeen - (Review Hate: l Jaa I9S5)
Sheet 2 Canaild
Fagu 1
COUNTRY AMI RtFNHRNCK HO
NAMfc OK iHIflAJS
I------
PATK Ob 0IHTH
--
f-------------1
16.05.1!)
1------ \
FIRST VC HFOfiUM
PATH OV DIAGNOSIS
AG* AT DIAGNOSIS
YEARS OF KXFOSURR TO
DIAGNOSIS
YKAHS OF urusiiKt
1 \----i------------- 1------------------ \
DATA OF ORA I II
I------ 1-------
H1STOLOCICAI. KSTIHATRU I CONbIHKATION EXFOSUM' | OCCUFATION
UtVRL
OTHER CAREER JilOlll.lGUTS
1951
1976
61
2)
H 00.04.77
|Reactat leieeuer
I------ 1-
lurttictf op* InUniace, packaging
OITlfcK COMMENTS
i l t i l l
i
l
l l
t
i
t
(
t
_____L,,
J
t
1 I
l
l l 1
\rlZ 90Q VWO
CO/-1"?
^.
^bjCcrU)
._ :?tATj
*oiess-v p-, *4th .c--- Jt
^lcnc.7
']f,i
" Lf ' U\i
v; A ! O o-v. . fir ^ Jjl J'-O. CVi . -4SJ7
t: T '-''Uf-t XrOU o f
IMl'IIJMAI. illMIU'At 1NOIISTK ll'S KM" KEIHnClIEHlCALS AND PLASTICS DIVISION
LIVt.H AngJoburnown f'.iyeu - (Kevlew Djte: l Jan IVH5)
4Kage
COIINIMY AND hkPkwkno: NO
NAME DM INITIALS
DATK OK BfHfJI
CZKUlu SLO VAK IA
06.0? .27
-4
Kiksr vo KXPOSUKE
DATK OK DIAGNOSIS
MOL AT DIAGNOSIS
10 12 13
TEAMS OK XTOSOHt TO DIAGNOSIS
YEAHS OK EXPOSURE
DATK OK DEATH
lUSfULOCICAL COHKiKHATlON
KSTIHATED EXPOSHKE
LEVEL
OCCIIPA LION
OrOEK CAKKKH HIOUMGlirS
16
(HHEK CtJHHENfS
Novelty
01.07.57 26.12.71
65
16 24.12.71
Novaky
01.11.50 27.11.66
37
14
15 26.11.64
Autoclave Cleaner
IAKC Itiur uf 1-4-02
giving Jcul I froi* Pruf A David ut Centre luJ Hygiene eml Otc illbcaueu.
Autuclave Cleaner
IAKC letter ni I-4-H2 gave uoMicuhat allured date* fai Lliltt eaue I have accepted the change* a I nee the ddtea louii f rua Piuf A David of ilu Centre of luduatrlal Hygiene Mini Occupetlonul OlucueeH. My datce cone originally t run NIOSII.
iz 9 oo yw o
tn
C o *r rn 7- V1.
Sub,jGct
" tc
y
i^Ss v
7 - J;d -
J4th .^Sr^Jno''
v' Or,j:
^udi, ,ou
Bo In
.b* zt?
'""i-'laca
JIU I liJAi miMlCAI. INMlIN'rrtJrS vi r FK.'IKtK'.Dt'ttirAGS AND PLASTICS DIVISION
CIVKK An|tloeurcuja Cnuca * (Review Date: l l**u 19H5)
Prance Sheet 1
Page >
10 11
U
tfMJimCY AND REKUKCHCK m
NAMJ-: UK INITIALS
1
IMTC OF fllKTJI
FACTORY
---------- f
etnar vc SKPOSUAK
OAT* OF DIAGNOSIS
AOK AT DIAGNOSIS
ifiAMS OF
EXPOSURE TO DIAGNOSIS
YEARS OF EXPOSURE
DAT* OF DEATH
HISTOLOGICAL f ESTIMATED CONFIRMATION | EXPOSURE
I Level.
| OCCIJI'H'rllM t
I
THK CAHFKH
| j
Ilir.HLICHTS j
1_________ i (
i
OIIIEH CilHHKNIS
---------------- -b
15.04.24
Kouaa11 Ion
00.01.46 18.02,67
41
---------------1
Ul.D6.tl
Rrlgjioud
06.07.59
15.01,75
61
--- ---------- 1
06.01.20
00.00.46 15.01.75
27,01.27
HrlguouJ 19.10.44 16.01.76
49
__{-------- 1
29.01.18
fcrlgnoud
18
O 3:
>
21 19 19.D2.6J
High
Autoclave worker end cleaner 19 yr*
|Ref. Havler iH jal Arrh. Hal.
|ProI. 1 H> ' |1 Nov 75 lt> 171-17/
16
12 24.01.J5
Yea I hjki> 2 yrn on |)CalJan
| Kef.
(NJUSK no |
aonower
|ur|gln
J(i bonneion et
cement) (
ID yrn mi
|a 1 "Nouvulie
polyner-
Ifiredue
1nation
| ne d 1 c a I u " j 5 Nov 1977
Ip 715
---------------1
29 29 29.06.75 26 26 04.01.76
I High Polyworker )VCM product J on |Mef. Kecy cl
I 10 yra an jl6 yrwjal Arcli. Hal.
l auluclave jltallao VOV4 Ifiot. 1 17 u`
leaner
|Shepherd,
|6 June 7?
Compounding jSawyer, Haeon |p 551-555
1 yin
*
i
I--------------- 1-
Hi Ki
Konotaer product Ion worker
Lts
PVC 11J tratIon 18 yrn
--
11.05.76
lt 1 Hi)
Folyworker 11 yre
11 )TGoracutOiy |Kef. F Cuudc-re |9th teh 1976 jet at "Seualnc
Jcoatal
jdea Gunptlau*
laiiglonurcoaa jtD SepivtsLiv
|2)Sclntigraj>liy|1976
| found ASL
| Frew 1 out* 1 y Gad
} l)llaeior rhage Jtooc
I f rota AS!, |4)Mgl.t
lan^Jouark. <iuy~ [Atoo
fjJcpatectoiay
I
J FI J 1i Gowak i el | a I " |.a Nouve 11
| F r u tt a e He d 1 c a J
|7(G July 197* jPaxe 2485
94V00
v> * to P;,
-* i
24th
teot;1 t'o _bfjc
vaQr
CaIa^01^ Dj'
Hr rofi ~4837
tz-l
arish.
ict
-Li,iana
iMKPKiAi chimjcaj. iNmismiKH pjx t'KOtOftlHMlUAl.S AND PLASTICS DIVISION
LlVKK Augloddrcnsta Caeee - (Review VUte: l l*n 19H5)
^'rjiiCtt Sheet 2
Pago It
mUNlKV Ml) kfc.NKNa: W
MAM K CIK Nil IALS
JtAIK OK bJKJII
b---------
14. 04/14
i---------
U?
01.04.14 Solway
OS.10.14
h
hactohv
FIRST VC KXKOSURK
OATH OK MACNOSIS
AGK AT DIAGNOSIS
YFABS OK KXKOSIJKK TO
DIAGNOSIS
WMS (V KKfOSlfKK
12
----- b
OATH OK | HISTOLOGICAL Dt-Afll | CONK 1 KMAT I ON
I
11
KSTIHATKO KXPOSURK
LKVKL
OCCUPATION
15
01HHK CAJCHKJt
hi cm. lours
J j
j
tirtlKK CuMHKNrS
Brlgnoud
12.08.76
42
t 11.09.Jt |
(HlOKtl |
..yu
j
11.09.Jb) |
I
I I
(1958-1960) 2 yra fIItret Ion 10-11 yra jyol yworker end woike IdM
|Title tun hud |A(H. prior to |AS. Ann. de |Nj1. Krot. Iluly *)) |p 645 A 6. jAOJ. woe found
|lu 1971 five I lyre before
t ----------------- 4-
Iasi.
h i-----------
St Auh*n 01.07.50 After
49
26
22 02.07.76 | fee
High
Haul fore- 1972-6 adoI
Idled ot
death
| (N f OSH no
iaatt In
uectlon In
|septI racial *
N10SH
| couNtent)
polyoer-
St Aoh.m
|Snail liver
aeye
1**1 Eon
lleelon IuuiiJ
00.07.76
Jafter autopay
----- b
Teveux
71.05.5? 03.12.75
42
19
19 30.01.77 J
Ho iterate 6 yra pecker
|Had been
I
4 dUttiClttVV
11mmol workei
i
dor
|previous]y
I 14 yra
I
autoclave
I
worker
St Foci*
10.01.4ft 26.04.76
20 28 25.12.77 | t
Very High 1948-1966 teener tapowure 1966-1976
PolyaerleetIon operator, eutocleaner, eutucleve d Jntenece
10 yre In eulplturlc dcId factory, etorefceepor & general eervlcee
|Operated 4-/6 I far rctaovdl of Jtoaour hunt
II Iver ad jdled tifler
leecund
|*urgfcvI [operation jfciiio
foi
|tunm hi *1
I fletolo
l^dpct by
|Or Kcty
dl
II it li t-ti Ucu
(Maladc*
Ifroledolunal j Vo1 40 No 6
I 1979 paged |?4l-l.
L ......... .
CMA 0 0 6 3 7 7
Tt~_2s yJGLotf to
-IT)]*-..
J4ti r<S20po r -^Wl -.
C^oay^f^o^t ^ Op
eU p'*
/)
r^' s*. :ot cou
IMI'MUAL OlfMlCAL UDUSJKffS PIT pk.rimun>:MjcAi.s and plastics division
MVhK Angiosarcoma C.i^b - (Review Pate: \ Jan 1985)
France Sheet *
7Page
CtJUN^KV AND HffKHKNCK NO
I---f
NAHt: tIK INI I'lAJ.S
11AT K Of mum
24.OS.19
~k------------------- h 5. >2,12 | HP
n 15
FACTORY St Font St Font
FUST VC &XPOSUHI!
HATK Of DIAGNOSIS
00.12.S6 10,01.76
00.01.4T 12.06.76
ACK AT MAHNOS IS
66
YKAHS Of KXfOSlIKK TO
DIAGNOSIS
21
37
VKAHS Of 61 POSURK
DATK Of Of ATII
21 10.01.76
31 13.11.76
JUSruUkOICAJ. COHfIHHATIUN
ESTlHATHIf | eimsuKE j occiieAi iim
I.EVKI. )
f--------- 1-
j
OTJJKJt CAFJUH HICIItlOHTS
High lAutod.ve
10 yra In
|eleaner
muchdulcat
t engineering
1 luduet ry I 1946-1956
_____________ I__________________
High
[mi-mt
|(ielyiet-
I (litloo
| general
Ipurjmae
| worker
11946-1972
(VCH
layntHeala j(HCI 6
| Acetylene) | forest <i ((agent
|de ualtrlee) im? jretIced
OTHfcM COMMfcNTS
Died ot pulmonary embolism 5 day* alter surgery
jl6.08.U
12
pcuk
Urlgaoui 09.02.49 OO.OS.79
~zr
30
27 23.06.79
Yet
High fMemoiaer
Jproduct Ion
jdikd jHJlyser-
|lnatIon
l9.0t.3T~t~Solvay
1
I--IT
n
21,09.61 26.06.79
40
13 22.08.79
loperatur______________ |Autocleaner 2 yra at eyeI elcigarelte
| 2 yr, (Autuluper.tor
l gte, |Cepolyere (4 yra
mechanic. 10 yre as enameller In tenItary were adiiufaetnrti
awnkur until 1974. HI all
ol 19/7 Joe to Oe^ophagcd) tfarlcea. Surgical
( Intervene tun
I 25.05.79
14 fS-04-24' Chloe
1941 foO.07.81
57
1--tt-4 36 29.07.81
dilute
(Formerly
HP)
I iirjt Very High I194J-19JS t4VlTS |AU type. of and Jjobd on futerultt-lwdnufdcture
1975-1979 maintenance work
(right be pa tec t 4b )
eittly
|6 Huilnieinttce
1975-1979 jin VCH Poly
_____ [Pcoceea
____ i______
CMA 0 0 6 3 7 8
Bo kp 1D;: n Y j j\ ^
Subject to' Protcc^i^rf^dor in Koss_v. jUonq.-o,_7nc., u0. cv0-''33?
14th Ju-Hc-iX -.J^icb Ci iiirt Calcasieu PiMau, Louisiana
iio.
Hi ill I.,,XI
INMiL. i k U,:-> RUSTICS DIVISION
LI.IMUXJ
LIVh'K AiiiilobjicuiBj Cdbes - (kevleti Date; I Fun I1HS)
UlilllC Sheet 4
H
1 1
i
i
1
VW3
UitmiKY AND XKHiKMJCK NO
16
O'
04
"vl
NAHK OH JNl HALS
da re (if bUlll
FACTORY
----- {
first vc
IMfK OF
KXF0S0RF. DIAGNOSIS
01.OJ .)/
Ghloe ChUte
(toiiucrly Kl*)
2D.09.42
Chiu* ChUte (Formerly
RF)
St Font*
I/.10.41 05.01.85
F--
Chlot chuie (ForaterIy
MX)
17.06.4ft 03.04.HI
4 AOK AT DIAGNOSIS
45
61
60
9 10
1
YtiARS OF
YFAKS OF
KXFOSIIHK ID KXPOSURF.
DIAGNOSIS
27 27
41 1H
11 DA'fK OF
DF-ATll
Alive
0}.06.8(.
12 li
T - r-
i
HISTOLOGICAL CONFIRMATION
FSTIHATKD |
|
F.XFOSURtS j OCCUPATION |
l.KlfKI, |
j
OIHCX CARFKR
HJCIIUCHTS
11 rr
ii
ii Yen Ulgh-2U yr lAutucldve |
Moderate 7 jrre
|cleduer 11955-1962
| j
Iddtocldve 1
tojerilor j 1962-1982
j |
11
11
Yee High-)) yrej Polymerlejt-|
Moderate }]qd Pruceeu J
Low - 5 yre|Mdii
|
ii [Maintenance \
JWorker
J
T"
1 1
T--------------------
| OJMFR j COHMPHl
i i
i i | J C Clllkl db |Letter of |5 III 198)
i i i \ i (Net 1 red j led 1979.
j J c: (Widd
[Letter* of j 5 |0 198)
|25 J 84,
|Health 6
|
[Safety AgentJ
1 i
i 1 `I
i 1
i
14
24 03.04.8)
Ye*
High -
|Auluclave |Otlier vector* |Met 1 red
21 ym
|Ciemir
|of Si Foil*
|l)l .01.79
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14th Juuicial District Court
Calcasieu Parish, Louisiana
IMI'I'M f At. (WHICAL INOUSTRiFS HC PKTKuUlhMICAl.S AND PLASTICS DIVISION
L1VKM AngloaarcoBd Caeca - (Review Date: I Jan 1985)
Ceriaany Slice t 3
Page II
I------------ 7
cun#iky and fiLFLHhNCK NO
NAMh UK INITIALS
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FACTORY
FIRST VC EXPOSURE
T~
DATE UK
ACK AT
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13
DATE OF | HISTOIOCICAL DEATH | CONFIRMATION
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ESTIHATED EXPOSURE
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OTHER CAREER HICHLItiHTS
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LIVER Anglottarcuma Cdueu - (Review Date: 1 Jen
935)
Page 12
11
t2
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1 || iCOUNTRY AND t NAME DR | DATE. OF |
j REFERENCE j NO
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S^eC^t^c BoTo - 4337 ^ jIlSTm^rict Court
Calcasieu Parish, Louisiana
IHt-IKlAI. CHE Ml CM. INtillSIHIF!; FI C fktruciiemicai.s an fi.astics nivisiow
l'*Ee 11
I.IVF.R ARtu4rcudj C4*e* - (Review Here: I Jen I9HS)
II
COUNIRY AND | NAHt (IN | OATE OF REFERENCE j IHITIAI.S j HI A HI
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CalcasUu Vum, Yonlai^
ihi'i:kjai nifMiCAi. jnihisthif.s vt.c Pt.filUClD-Ml LAI.S AND PLASTICS DIVISION
LIVES Angloeercomj Co tie a - (Keylew Date: 1 Jan 1965)
10
* Should U*la caau be removed fro* Hie list? NIOSJt have It un their eupplementury Hat relating tu nun-polyuerleatlun wurkere expuaed lu VCH.
is i/am
12 IS
Page 14 r`
1 ji 1
CMA 0 0 6 3 8
COIINYhY AND KEFfeNtNCK NO
ITALY
01 (On KlilSIl
eupplewentary Met)
NAN*-. |)H INITIALS
OATH OK HtHTtl
l5.06.14
FUST VC KXFOSOHK
00.00.6S
OATH OF DIAGNOSIS
19.04.71
AGF. AT DIAGNOSIS
16
YEAKS OF KXFosime to
DIAGNOSIS
YEANS Of RJtfOSUNF
DATE Of DEATH
16.04.71
HISTOLOGICAL COKFHWATION
BSTIMATKD | KXI-tlSttltK | OCCIIfAriOM
UVBL j
_________ J__________
j
|PVC Bog |txlru*ler
OTIIFN
CAMKK HIGHLIGHTS
OTHKH COMMENTS
Primary i may have perlcardl Not howugeneuue wit other caeca
f--+
02 I3.11.29 MoniedI eon Porto Harglie rt
41
27.12.72 | I
f---------- h
14.01.20 Sotvay
oo.oi.Si I0.07.7S
22 21 10.07,75
04 20.07.1? ANIC
*
------------h
00.04.S9 00.01.81
4S
21
21 30.03.HI |
I I
!
ti LUntfH I U 19 ,01.1?
Hire Venice
00.00.67 O? .OS.HS
16 06.0*.S3 | t I
t
** See h.ittunl Med -11 lavoro 65 p445f 1974. Further deialle In letter from Dr Honteaeno of I ARC on April lt 19B2.
J Hoi/worker \
High
12 yre Very High
fAutuc teener jd yra (1953-
1972-5 did a variety of
|6I) Autoclave Jobe
|operatur
including
112 yra (1961 PVC packing.
j 72)____________
r
Jl yr -
Never cleaned
]Monomer
eutoclavee.
S yre Medium
4 yre Low
(operator
See paper by
| CHIAPP1N0 et
J20 yre -
el Hed Lavoro
| Autoclave
Voi 6 (1962)
(operator 6 pp 555-563
(other duties
Jlu euapene-
|lon polymer-
Non-awokei Gone uucil
little alcohol. AOL.
(leatIon.
I |Area fureman
11n edue Dept
lattice 197S.
Medium-? High
~T
Jpeg extruder 11967-1975
jComwerclal | Dept 19761190)
J_______
S Pagllaluliga telex 2 Aug 19B1
*** Alau bee Hj I tunl and HoiidlneJIa lu Acta Onto I ogle a Vol 1 19B pegee 35 - 49. (1C) hue made a translation of tlila paper Into tug I talk mid coplca of the tranalaliuii can he made available on requeet).
9 8 9 0 0 VW3
CONFIDENTIAL
Subject to Pi';; I;t..''-t lvc Oi-tier in Boss v. SS'-'T'0- 1 ,rL- -- 90-4837
14th iii ' - i 7. C-i -rt 'i. rt Conrt C'h.ler,r; I r,J ir i '~h, T m I ,=? i
IMPTRIAL OHKflll'AI. INiHJjiTK J .H H.C PKl'KiU'IIL'MICALS AN1) PLASTICS DIVISION
I.JVPK An^Ioiurcoua Cjs*s - (Review Date: 1 Jan 1985)
* In hit* ltitcr of l*t April 19A2, l>r Huutenauo of IARC nay a Japaiwee Hlnletry of Ubout give
Udie ot tUdgnoaltt " 21-08-74 AgU Of diilgtlOdlft - ii Year* of expuaurti - 22
15
_co; Subject to
Ross y, n,,..r
>, L:~i / . , "" - --
?.! L
Cl
C-(7Cr ln
1;o- 3-^C37
IMPERIAL Cl I KM |CA I. INDUSTRIES VIC t-KTHUCUKMiCAl.S AND PLASTICS DIVISION
LIVER Angloeercutue Ceecw - (Review Date; 1 Jen I9fl5)
Puge 16
H------f~
CDUNTljY AND
HANK OK DATE Of
REFERENCE
INITIALS
BIRTH
Nil
10 n
12
14
HURT VC ennimtf
DATE Of DIAGNOSIS
ACK AT DIAGNOSIS
WARS Of EXPOSURE TO
DIAGNOSIS
TKAAS Of EXPOSURE
DATE Of DEATH
JIISTOMKilCAL CONFIRMATION
P.ST I MATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREEN HIGHLIGHTS
OTHER COMMENTS
Norek
Heroy*
00.03.5ti 21.12.71
56
22
21 04.01.72
Hydro
mKi*
Foreeen 6 Autoclave eu|Hstvlttoc
Cont lilted by Dr Hi IIuEvuneeu ot Nil At APME Mift ot 9 June 107ft Nr P Haugneu eieted that All lied Leva a ate tuber ul a etui t -ufi Icju. VCH 6 fVC ueie mede in uame bo 1 Id I ug . Tile VCH wee aude I run uceiyIe
ChA 006387
l_.
CO"'."; ' . V T,
tc-b i,n
rV;j
in
Eoss V. j.';. u,
i-0- 4337
2^ uh 2lj-; ii r,; - iriot Court
Calcasieu I'uv'i ah, I o*j i a i ;n,i
IHI-KWIAl. CIIFMCAI. IHIWSTKlyS EI.C rKiKtH'.UKMU ALS AMU PLASTICS UlVISlON
L1WKK An^loeurcuud Cauce - (Review Date: l Ja 1985)
Page 1/
COUNTRY AMO REFERENCE
SWEDEN
NAME OH INITIALS
-L J
-H---------f-
it ak of |
| HAST VC t BATE Of
ML All! I CUHPANT | fACTOKT I EXPOSURE j MACHOS IS
I
II
I
i--h
I
21.06.27 I KendiiorJ ISund.v.llJ IA.OS.51 | 10.10.70
-I-------------------------- 1_
27.11.11 | Ee.-wortl |Sund**all| 00.01.45 | 00.08.72
10.06.10 | KtuiuU
--------- f-
16.M.14 | Kemaitorii I
\---------h
|Sundnv.il| 00.05.47 | IS.01.76
"I----------F
(SutulevalJf 00.00.46 | 12.05.77
1 I I I
I I i I I I i
------------------ 1-------------------- 4------------f- -------------------lP_____________
I 2.0).19 | Keiitiaurd
-1_.
ISundml 11 II.05.64 | 22.11.HO
II
I
II
II
tI
\t
J_______L
*!
i t1
iii
9
1 ) 11
t
12
i ii
1 1A
1
_______ L
1
1 1
t1 11
11
t1
TI
HOF AT J YEANS Of | TEAKS OK ) OATH OF t HI.STOl.OC [CAT | ESTIMATE!! 1
1
MACHOS IS j BXEOSUKK TO | EUPOSOKE I HEATH | CONFIRMATION | EIEOSUHE | OCCUPATION t
1 OfACHOSiS 1
I1
| EEVHl. 1
1
| 1 1| 1 1 fI
1| 11
j r
j 15 |
( "1
OTHER CAREER
| (
HICHL1CHTS
l ! 1
16
' OTHER CUtlMkHrS
1 |
AJ 1 19
| (
1i
J
1 1i 1 18 J20.I0.70 J
tem
J
I I| 1 11
1 i
it \i (Polymarker (
|j 1r
l i l
I
61 | 27 1 1 1 1 i 1 i 1 1 | 1
1 i
65 l 29 } 1
1 27 1 1
J16.0S.77 |
|j
jj
Yea
1 Hl*li |
1
JVCM
|
|product loo |
ii
1 11
1i
i
1 1I
ti
i
1 1J
Ji
i
1 11
ti
i
1 1t
1t
i
1 11
1i
i
1 11
1i
i
( I1 1 11
11
1i |i
Ji
j
i i
I 1|
1 ii
1 21 JI9.07.76 |
Yea
i 1 Hljlli
1i (Polyuorkcr |
I 1j 1 I1
1 1
j1
1i
(Mr SJoelIn1a (letter of )2fl March 1978 (confirm* bL |waa a uiuiioiacr (worker whu wau (heavl l y
,(eapoaed
(probably even juulv Ui> than (a ttotwal | Icuctoi' (cleaner
| i
j
j
62 1 1 1
1 |
1 1 | i
i
i |
l
________ L 1
61 t
f |
j
1 1
________ L
11 16
t
112.05.?? {
1 ii
1 ii
1 ii 1 tt
1 ii
J ii t ||
1 ii
1 tj
i ii
1 ii
1 ii
1 i}
1 11
1 16 122.11.60 t
( ii 1 ||
I ti
1 jj
1 ii
J_______ J_______ L
Yea Yea
1 Hih
t
i 1 1 1 1 1 i
| j
J 1 t
1
1 High | 6 Yea re ( Low J 10 Year*
i |
(1966-1958 jpuly.vr-
) j
[UttlOA
|
(worker (12 j
(yr> 4 1958-J (1977 fureaduj
|(19 yr)
|
t1 11
11
11
11
11
Ai________ 1i
|1964-t970 |
}cuir{fage |
(operator
(
(1970-1980 J
|drJcr
|
(operator
|
JL
JI it firm 12 (yrw of (eaiploytueut Jia<J (been lieavl ly
(eapoued. In (1974. liver tatmorualt ty (ami hocio1a |d J AigAlObt.-J .
|l)ala cuuf UmciI (Iii Ur D Hyrcn lleticr 1H.H.77 [to CKE1C
J
T ----------------------
|Let ter of Jij Mdv 1981 '
(ft Ulll
|0r David Wyiunl
ti (t 1J
8 8 2 9 0 0 VW3
In Mu Idler of lut April 1982, Ur Honteumiu of IAHC any* la Sweden1* Ndttuaal guard of OS Health give* 2U-02-70 a* date of diagonal a for Case I1 and 15-05-72 fgr Cuee 1>2.
C0Lr'1T^r:iT tal
Su'bjc Eos_s_ v.
,0 rJ t.vj .. . ; 0.."!cr in a, i;o. fjO-40,37
14th Judicial District Court Calcauic-u Pariah, Louisiana
ihi-kkui. nmmc*L immsi-mus mx:
VKfKl H.`HKMl0A1.S AMI) ELASTICS DIVISION
LIVER Augluuarcotud Caca - (Review TVdte; \ Jen 19B5)
mt
Sheut t
ta
ClWNl'MY AMD RKviKENCfc HU
NAME lH initials
j
DATE W IIX HIM
COMPANY
rikiif VC I DATE OF exposure j machos is
I
AfiH AT DIAGNOSIS
YEARS OF EXPOSURE TO
IlIAUHOSIS
---------- 4-
YEANS OV
exposure
OATH GF | JUSTOI.OCICAL DEATH j CONFIRMATION
I
KSTIHATED EXPOSURE
LEVEL
14 OCCllI* AT I OH
OTHER CAHEEN
highlights
16
aim* COflHEN FS
2il.OA.OI
I--------1
02
eiw
H
isr
4--------1
23.06.20
iliUhouK
* 04.0A.AA J 01.32.72
I (Vo* A | CoUler | paper aay* J 21.32.72)
71
--------- \
Uttrrjr
1 00.12.74 1
J_____________ 1
| 00.06.79 1 I 1 t 1 I | 1 1 | | t | 1
t 1 1 1
1 t 1 1
1 t 1 1 1 1 1 1 1 1 1
37 i i i
.i I
59 i i i
i
i i i i
i
i i i i i i
09 25
22 01.12.72 |
(Vo* A |
Collier f
paper
j
Mays
|
21.L2.72)j
I
------f
i J.S 1
1
1 1
t 18 i i i i i i i
i
i i i i i i
------------ \-
124*12.76 | 1t 1I |i 1I
112.10.79 |
ii ti ti ii ii ii ti ii it ii ti ii it ii
Yea Yea
500 ppM
1944-7 VCH 1947-0 Drier
1940-61 Autoclave operator 1961-66 Drier
Lee ami Harry Lancet 29-06074 page* 111 6-0
Dubious) f abr ftat Ion caae
1 Higll
t t
| Autoclave |cleaner t
( 1 1
1 1
i1
t T
| Kediu*- |54-5
|Pre-war fleli
1 high
|packer
1
|Plaiit
119T9 SS ar.y
1
|55-6
|veltlcle
1 jorler EUui |uta 1 nteminre
t 156-50
|T5t5-54
1 ]Autoclave |fluh packer
1
(worker
t
i1 150-61
i1 | Chargehand
t1 (Drier
i1 (tUm
i1 161-72
i1 | Forced ii
i1 ic 2/] rinut
E&poeure I lit! let] iu 2.66 - 9.69
CMA 0 0 6 3 8 9
--1____
COFFT^TTTIAI
Subject~to PiuL'.ctI'.o
in
Boss v. Ocr-; o, 1. n_. , V.-i. ?0~-'Q37
Jlth
~
C' 1r ''' ' ' '
JHI'IIIIAI a I KM :.M. INDUSTRIES H.C m'KdOtKMICALS AND H.ASflCS DIVISION
OK Sheai 2
fa*e 19
i r * ~r
I
'jC011NJKV ANlDi | NHAMEE' OOHfl~| DATE~OK~ |~
-1--h J | FlttSI VC j DATE (IF
KEKEKKHCE j 1N1TIAIS j B1HTD J UlHKANr j FACTOHY j EXKOSUKE j DIAGNOSIS
INO
j--------------- _].
US |JE
JID.01.14 BE
Barry
OB.01.51 00,10.7V
I
[ueV
1911
II ^sVdOoll OJ
OB "Job.os.24 1
Burry
[" 1962
09,01.BO
Barry
f* 1461
00.00^0
Barry
" 1 19 .'09. SO 1 27.11. .81
I IVKH Aug oaarcuoa Canes
(Review Date: 1 Jan 1985)
10 7 11 ~T
12
Tn 1
14
15 I------------ nr
ACK AT DIAGNOSIS
TEARS OF EXPOSURE TO
DIAGNOSIS
YEARS OF EXPOSURE
DATE OK | HISTOLOGICAL | ESTIMATED | DEATH | CONEIHMATION j EXEOSUHE | OECIJKAITON
_____ J
j LEVEL j
OT1IEK CAREER HJUM.ICHTS
( j
OTHER COHMKN rS
65 28
lfl7T
18
60 17
57 II
21 19.11.79 j
09.Ot.BO I 12
8.2 I1.06.B0
25.12.BI \
24 1--------1
I
1 1 1 I 1 1 1 I 1 1 1 I 1 1 1 1 1 1 1
11951-52 (Polycleaner (1952-55 (Latex 11955-60 (Polyfluor 11960-64 jpuly
(Chergehand 11964-70 (Charging (operator 11970-72 (Drier (operator
"(7 yrs
|l950-195B
|500 p|H>
{1968-1974
|2O0 pp.
1
|
j 1 1 1
|
|
1 1 1 1
| |
1 1 1 1
|Foly Floor (Operator |S yra (Greaaer on (Poly Floor fpolycleaner 11961-5 (Recovery (1965-1971
1
11950-51
Il91fi-194B
| Autoclave |Motor Mechanic
(operator
11948-1950
11951-1957 (Operator on
l Charge aii (Acetylene
(autoclave
j bull.) 1 iik
| Productton (Plant
11957-1974
| Shift
1 1
(ettpcrvlaor 1
lautoclave 1
(building - 1
|Never
1
(cleaned
1
(autoclave* 1
Ibut
1
(eupcivlnor a|
| fob enta1 led(
(entering
1
(autoclavee |to luapect | the*
1 1
1
CMA 0 0 6 3 9 0
_C0NF.{ r>?yiTI.j\L Subject triTolr-Vt:^' older in
Boss_ V. _Co_no-
]?J. SO-4337
14th J "iio\;i!! r.inLnct Court
Caloa. f-l!
i'.t-y[[, Louisiana
IHPKU lAl. CHEMICAL INJHISTKfKS PPJRUCHKHICAI.S ANU PM ST ICS 01 VISION
LIVKR AnftloaarcoMia Cabe* - (Review ttate: 1 Jan 1985}
UK Sheet J
COUNTRY ANO R t PERK NO!
__ _J|U_______
uk
` 09
NAME OR INITIAL5
OATH OK j mum
rIRSr V<T~|" BATE
FIRS
OK
FACTUMY KXIUSUHK IJI AC NUStS
+
Itarcy
15.02.50
a]
9
AC.H AT 01 MINUS (S
YKAHS OK EXPOSURE 10
OIAONOSIS
11
10 T
T 12
n T 14
15
YEARS OF EXPOSURE
DATE OK OKA fH
HI STOI.OC ICA1. "f ESTIMATED CONFIRMATION EXPOSURE
J.KVKI.
occupation
OTHER CAREER II1CMI. ICIJI'S
29 24.02.Si
Heillu
Polyworker
2 years ou AcrylonJtrlla Realn Plant. Also prior to 1950. 4 yeare RAP ua] ntenance. 1 year* walor car palnlahop. 2 yeare in Craving Dock.
Page 20
16 OTHER COttttKNrS
04.04.A?
Harry
27.04.66 01.05.64
IS 4.2 J6.05.84
High - II Polycleaner Heavy gouda
lUJiitha (500 1966-67.
vehicle drlvei
ppw). Low- Spray - irlet UUt11 f tUttl
16 wuutlie (50 ppn).
bagger 1967 1 I hie*.
68.
HeJIus 21 BOkitha
Slow down stripper
(200 pin.) operator
1968-70.
lufuraatIon given In letter 18.06.64 frua Or I) H J UUtl awe
CMA 0 0 6 3 9 1
CO'rr T t
Order r*1
Sutjeci
)"-
, 9Q-4837
Eosc, -r -y .
ijlstriot --UJ-
14tu J!U'J;_` ...-y
LouiaI'iaa
Calca^-o- "*'
IHKi Kf Al. CHEMICAL INUUSTKIKS PLC PliTHUCHPHICAl.S A HO PLASTICS DIVISION
LIVER Aug loearcoiia Cases - (Hevlev Date: l Jan 1985)
*UK syuteu of dates DAY - MONTH - YEAR
USA Sheet 1
Page 21
COUNTRY ANU HEKfcKXNCK NO
NAME OH INITIALS
OATH OP HlKTN
"1-----------
Earl Perks
17.10.23
FACTORY
MUST VC | DATE OP EXPOSURE j DIAGNOSIS
ACg AT DIAGNOSIS
Louis ville
i i 04.12.48 | 03.01.71
I
49
-1----------- 1
11.OB.13
I-------- 1 --------------------j---------------------
Louis ville
11.11.15 | 00.01.70
\
---------------- 1
EJWdl hi Olewlddle
Louis ville
28.11.41 ( 14.12.71
-------------------- \
i--i
15.01.24
l.oul -
06.07.S2 | 19.08.67
Ills
I
-4----------- 1
43
OS
25,01.12
JvOul S-
14.06.44 | 04.04.64
52
viile
l
1I_____________
Key Aubtla Joneal
2).11.26
Louis ville
17.01.62 | 00.07.74 I
45
\
Charles t Suer).
[
03.05.22
06.05,20
Goodyear
I-----f
S Ctisrle- 27.06,44 J 00,00.68 a ton
H----------------
Niagara
07.10.46 | 00.04.61 I
41
10
YKAHS OK EXPOSOHP TO
DIAGNOSIS
YEARS OK EXPOSURE
DATE OK DEATH
HISTOLOGICAL CONFIRMATION
24 21 03.03.73
14 n 27.09.71
(NlOSJl says 28.09.71)
-------------- 1
28 26 19.12.73
15 15 07.01.68
20 20 09.04.64
-----f 12 24.07.75
------------- 4
24 17 23.03.64
29.08.61
13
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
011IEN CAREER
HIGHLIGHTS
I----------------------------I
J OT11KH j COMMENTS
j|
Put Cleaner (Muck Jaata
(974) p 53
History given {Moiling Stone
In Annals NY (Art
ACAD SCIENCES {Ref 1 NY Acad
Vot 329 (I979)M Sc Syp
page 190 in |1974
Paper ly
|Albu block
tt R Cut tine ut|Jaiad 1.7.74
OSIIA
jp 51
-------------------1
Pot Cleaner (Of Muck)
[Kef I J A1ao Block |JAMA 1.7.74 Ip
Pot Cleaner (Cl Block)
LoulsviJle Courier Jourubl 02-09-80
Put Cleaner (Cf Block)
] He f I |Albo block
|bef I |Albu block
Pot Cleaner (Cf block)
| Net 1 J AI bit 81 ocfc
US Air Force
Pot Cleaner (Cf Block)
|Kef I t |LouievlIle |Tluca 21.7.75 jltellrcd April |1974 ) Aleo Block I
1 Ret I
-I___
CMA 0 0 6 3 9 2
Curi^Ti^^TTAL
Subject to Pruicji. u j Oif'or in
Eo v. Conooo, f'to, to.
4837
14th Judici:3~I)ie>tr 1 ct Court
Calcasieu Parish, Louisiana
IHPLMAI mUICAI. JNIHJSFKIKS PIC KKIKO*:UKMICALS AHU PLASTICS DIVISION
LIVKH Angtondri'.oisd Caaee - (Review flute: I Jen 1985)
*U1C eyatea of datee DAT - KONTU - VKAH
USA Sheet 2
Pdge 22
----------------------- (------------------------(-----------------
I
12
|1
1_____________________________ ____________
COUNTRY AND I HAHC UK | DA ft W HtP'KHKHCK 1INITIALS j tt [ K l`tl
NO |
j
COHFANV
1
j
I
T ----------------1---------- 1
I 10 I i`
n 14
TT
T
1 T
T
| FUST VC | OATS OF | ACE AT ( YEARS OF
| YKAHS OF | OATS OF i III Sill LOO 1CAl. | ESTIMATED J
jFACTORY j EXPOSURE j DIAGNOSIS | DIAGNOSIS j EX EOSIIHE TO EXPOSURE. j DEATH | CONEIRHATIUN j EXPOSURE j OCCUPATION
j)
| - | DIAGNOSIS III
I LEVEL j
16
GTIIKK CAREER HIGHLIGHTS
| j
OTHER COMMENTS
r 1T
1T T
`T
1
l----------------- ~ll
~1
I
1
USA i
t
11
l
t
i
i j[
11
ii
09 |Hdymond |OB.Il .11 l RFC
(Celtic[linger?
i i
1 | j
j
t 1 i 1
| t1
j Loulfl-
28.05.45 1 01.03.74 i
43
29
j yin* 1
1
t
i
t1
1
i
|1 j1 j1
t
i | i
i |1
i1
|
| 11
|1
1
i
! 11
l1
1j r 1r
11 i1
! 1
l i
| 1
IU
| I6.U6.13 i Goodyear |HI ager
12.06.51 00.05.66
55
17
1 |1 r1r
|| 11
| 1
l j
i
ii | ti j 24 til.03.75 |
i ii | ii j ii
i ti | ii j ti j ti
ti
t i{ i it
1 u |10.0S.6S |
t 1
|1
1 (
Tea Yea
| j 2000 [>pa i | i | j
i |
I 1
1 1 1 1 1 1 1 1 1 1 1 11
1 It i4
1 1 1 1 1 1 1 1 1 1 1 |1
1 j I
t i (Ref 1 Dae (wrung figured |re ftral leapoeure. |Luulevllie jTlmce 129.10.74, 1I2.1.7S, j10.1.76
1 1 1 He T 1
1i
II i
I27.0S.09 i Goodyear |HI age re
14.10.46 1 00.03.70
61 i 23
t1
I 1
1 T
11 iT
11
i
11
12
llrdMcln A 117.11.18 t VI refttone (Pott a town] 13.07.49 02 .05.69 |
50
i
20
(Bachman 1
1
1 **
ji
i |1
i
ji
t 11
i1
1
i
i
i 11
|
|i
i |1
|
ji
| j1
i
1jt
11
i
|
J
j___________ 4.
1
4-
1
1 11
1i
i
1
i
13 (Richard 101.12.21 1 ucc
(Kdward
1
1
(Cteudenin !
1
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JHPClUAL CHEMICAL INDUSTRIES VIC PKITKICIICHICAJ.S AND PLASTICS HIV I SION
LIVER Anglouarcoua Cat>ea - (Review Date; l Jen 1965)
UK Syetew of liatea PAY - MON 111 - YfAft
USA Sheet 3
Page 2i
:Ollf^JMf AND REKERRNCR
HD
NAME IIIt INITIALS
DATE OP b[Hfrt
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16 Jumoh 04.11.27 IJowa rj
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DATE OP DIAGNOSIS
ACE AT DIAGNOSIS
---- 1-
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YEANS OK | DATE OK EXPOSURE j DEATH
HISTOLOGICAL CONFIRMATION
i--i--iDIAGNOSIS
11
ESTIMATED EXPOSURE
I.EVKL
14 OCCUPATION
OTHER CAREEN
HIGHLIGHTS
| j
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OTHER COMHtNIS
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06*05.50 00.00.69
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LIVER Angiouarcut*j Cases - (Review Date: l .Inn ]9tt5)
*HK systeu of <|ntei DAY - HOItni - YKAH
USA Sheet 4
Page 2 4
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CONFIDENTIAL
Subject to Protective Order in Ross v. Conoco, Inc:. , Ho. 90-4837
14th Judicial District Court Calcasieu Parish, Louisiana
IMWKIAI. niHJIOAL INDUSTRIES Vl.C FE I'KUCIOHICAI.S AND Fl.ASTfCS DIVISION
LIVKK Angloaarcoad Cuaea - (Review Date: 1 Jan 19115)
*lfK ayatem of date* DAY - HON lit - YEAN
(ISA Sheet 5
Page 25
ii
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14VKH Angioma rcnooa Cuaea - (Review Dale: 1 fan 1985)
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(Teat Lug (cuuuuc nred |MJy 1961
CHA 0 0 6 3 9 7
CO1': I'
Subject tu ' ou. . : C. cor in Boss v. Cono-: -in , ho. 10-4837
14th Jodinio.1 P 1 - ti-ict Court Calcaulou Puri oh, Louisiana
IMI'l'JU.U. CMHIIC.M, IHIHJSTKIKS UHtTKU Fl-ASTll'-S DIVISION
1.1VER Ang luearctwaLt C.iaea - (Review (late: l Jan 1985)
USA Sheet 7
UK ayate* of date IH1 - HON11I - YEAR
Pago II
COUNlKY ANU REKKKEH MB NO
US II
NAME 4>K ihitiai.s
Hi I fa y t on
A fH. OK BlHTH
---------b-------
29.08.29
US IB
28. 08,22 Afr Product*
------------ 1
FACTORY
first vc BMPOSUttH
HATH OF OUCtfUSlS
Loulavllle
iim
06.0A.84
Calvert City
00.02,61 19,01.83
ACt-i AY OtACHOSlS
54
40
YEARS OK EKKOSUKE TO
Jl/ACNOSIS
19
JQ
TEAMS OK EXPOSURE
DAW OK DEATH
22
19 28.10.83
IIISniUKlICAL CUNKIItMATllM
Yes
n
ESTlrtATKU EXPOSURE
I.EVKL
OCCUPATION
High
Worked regularly In KVC area. In the early day a waa a reactor cleaner 1953-/5.
~\
nigh 1963-1982
Normal pcogresalott from helper to ucuJor ope rat or, cleaded reactor*, tripping and recovery aica* an well aa charging operator.
15 lb
OTHER CAREKk HI (OIL! CHI'S
tmtfcK COHHKNTS
|----------------------------
lInformaltun (given Xji |let t ci (09,08.84 tiw* | Ur H N (uluiaoo
I-------------
JThrowho Jcylopcnj* and | I enktipeii 1 a |aIace 19/8.
treatment (for urlhiltla (19/6. Under JUr * a care (about 6 wi>utt(i |betore death-, (had poaueJ
(a t anda d Iphyulcal caam(Illation 1 Jtaoniha (earl lei. )J Karr letter jot 22.10.64.
i
I
CMA 0 0 6 3 9 8
Subject to l!
,, ,r Bo_ss_ ^
rnnc^1 :
-1
0 V U' 'n
_ Vj_ 90-4337.
-
- |l,_s T.- r.
t\.;
ict
Courlt.
>nh
Calcari ou
Louisiana
n.cIhNIHlAi. Till Ml CAL INDUSIK IKS
PKlHOrilKMICALS ANN PJASTIGS DIVISION
I.IVKH An^tii^dtcuiiM Cjsei* - (kevtuw Date; l Inn 1984)
Pago 2 6
COLItflliY ANN KISPKHKNCp
NO
NAHK OK INI HALS
[
YUGOSLAVIA
DAIK OK HI KIN
05.04.14
Jugo VWill
15,11.31
Jugo Vlnl I
21. 12,11
Jugo VI nil
b~
Jugo Vinll
spin Split Split
Spilt
t'IK ST VC KPUSUKK
NATK. OP DIAGNOSIS
AUK AT DIAGNOSIS
YfcAHS OK PMPOSDHK TO
DIAGNOSIS
YKAKS Of P.XKOSUKK
DA'IK OP ItfATH
HISTOLOGICAL CONK1HMATION
------------------------!_
15
KSTlHAfKU KXPOSUKK
J.K.VKI.
OCCUPATION
DTttPK CABKKH HIGHLIGHTS
oriiPK COttHfeHl'S
00.00.53
20 06.04.73
00.00.50 12.07.2J
42
23
----------- \
12.07.73
Yen*
04.06.54 11.01.76
45
22
22 11.01.76
Yen*
15.12.5ft
46 2D 1ft 03.09.76
VC Productlau
Vt'Ji ProductIon
SAKIC ct ul p-pci fcuv Mud UN Pc r ei |iuct I ve Vul 17, pp 169-192 1976
* Jit til a lei l lit
ul J Out 1976,
Di Sptrlud <>t NIOStt changed the MUiuii uf Laee 02 to VCH p roduc11on cwpIoyee. Nr SpliIdd a leu mi1tiled A JltMrf (iuu 0 1 a] HO ii VI H p 14 id IK t I Oil uuik<r
Kota Kiiul nek l letter ot 1 SILIi tune I960 and J AH I' letter at I Apr II 1962
C li* 006399
CMA 0 0 6 4 0 0
table; l
(Review Date - 1 Jan 1985)
Incidence of ASL Cases Per Annum
By date of death
1955
6
7 8 9 1960
1
2
3 4 5
6
7
8
9 1970
1 2 3 4 5 6 7 8 9 1980 1
2
3 4
Total
1
0
1 0 0 0
1
1
0
2 0
1
1 5 3 2 3 5 7
6
11 11
9 10
5 10
4
1
7 3 109
N.B. 1 Does not Include Italian 01 but does Include German 03.
2 The 1977 total Includes US case 24 which Is a Choiangiosarcoma
3 The 1982 total does not Include US 33 who is alive and F 15 who Is alive.
4 The 1983 total does not Include US 36 who is alive.
Page 29
Distribution of ASL Casea by Country
TABLE 2
(Review Date - 1 Jan 1985)
Page 30
USA W Germany France Canada UK Sweden Yugoslavia Italy Czechoslovakia Japan Belgium Norway
35 ***
21 ** 37 *** 10
9
5 **** 4 *****
4*
2 2 2
1
S& %
A% v \Oi J^?r' A- *
cl AO,
A'vi V,v:-AVO9, ,,vA<s\\\.A1 ?; O l C A ,\ L
yVo,\
V. ,
Cov\-A
vA*. v'A. \ AN A
% AA
A3V
% o%$
v*,. n >
Total
11 9
T06-900 VW3
* Omit ItOl - atypical case of PVC bag extruder. ** Includes GE03 aerosol can filler. *** Includes case US 24 which was diagnosed as Cholangiosarcoma*& US 33, and 36; and F 15, who are alive. **** Includes one monomer worker. ***** includes two monomer workers.
i.e Western Europe North America Rest of World
59 45
8
Total 112
Pattern of ASL Cases by Factory
TABLE 3
(Review Date - 1 Jan 1985)
(a) W Europe
Of the 59 cases in W Europe, 49 have occurred in clusters at 11 factories. Of the 21 German cases, 18 have occurred in clusters at 4 factories.
ASL Cases
Dynamit, Troisdorf Chloe Chirnie (Formerly RP), St Fons BP, Barry Kemanord, Sundavail PCUK, Brlgnoud Wacker, Burghausen CWH, Marl ICI, Hillhouse Solvay, Tavaux Lonza, Waldshut Solvay, Jemeppe
10 8
7
5 5
4 2 2 2 2 _2
49
NB: There are 31 pre 1962 PVC plants in W Europe; 18 of these have had ASL cases (Ref Table 8)
(b) N America
Of the 45 cases in N America, 38 have occurred at four factories out of a total of 49 factories - in N America 38 plants have not had ASL cases.
BFG, Shawinlgan BFG, Louisville UCC, S Charleston Coodyear, Niagara
ASL Cases
10 14 10
4
Page 31
t- - , 'I "
u < > ;"
'cY O''
CMA 00640
NB: Usere are 29 pre 1962 PVC plants in N America; 11 of these have had ASL cases (Ref Tables 9 & 10) (c) Rest of VJorld
The 8 ASL cases are believed to be in 1 cluster of 4 and 2 clusters of 2 cases.
TABLE 4A Latency Periods (Years from first Exposure to Diagnosis)
(Review Date - 1 Jan 1985)
Page 32
Country
No of Cases
Total Years
Average
W Europe
Belgium
2 35 17.5
France Germany
17
438
25.76 *
21 385 18.3 *
Italy
4 74 18.5
Norway
1 22 22
N America Rest of World Summary
Sweden UK
US Canada
Czechoslovakia Japan Yugoslavia
5 9 59
1
35
10
45
2 2
4
8
122
207 1283
885 204 1089
30 39 85 154
24.5 23.0 21.75
25.29 * 20.4 * 24.2
15.0 19.5
21.2
19.2
.\w 9<,
P, ct <1 IS V'1 . O
t V-
`J \^ijs
rr O
v\wvv
i i i \ V-"'
'P O i . )
\i-
; o
t\
. c> \ p*
o o o o\tP1
p if is*
u) O -,n /(J
Pb '
0H
t-*
CD cV CD d
W Europe
59 1283 21.75
OVVOO vwo
N America
45
1089
24.2
Rest of World
B
112
154 2526
19.2 22.55
Of the countries with 10 cases, France and USA have average latency period above world average and Germany well below
DISTRIBUTION OF LATENCY PERIODS TABLE 4B
(Review Date - 1 Jan 1985)
Page 33
1 1 1 i l 1 1 II II
1 I 1 i 1 1 1 II II Average 1 0-9 yrs | 10-14 yrs | 15-19 yrs | 20-24 yrs | 25-29 yrs 1 30-34 yrs | 35+ yrs || Total II Latency
1 1 1 1 1 1 1 II II Period
1 1 1 1 1 1 1 II II
11
| Be lg i uni | Canada
1
I
1
| Czechoslovakia 1
1 11
1
4I
1 11
| France | Germany | Italy | Japan | Norway | Sweden | UK | USA | Yugoslavia
11
| 1I
11 11
11
I 1J
11
I 1i
11 11
11 |1
11|
I 11
11 11
I1
1
1
i1 3I
I
1
1|
EP 1|
11
4I
11
i
11
i iE
1 I 1 1 I 1
1 11
2|
1l
i
1
2I
11
1 11
1|
11
4I
11
9I
11
2!
1E
1|
|1
i | 1
21
Jl
3I
1 i
8| l1
i
1
1
J
5!
1 1 1 1
2|
11
6* 1 I
1
2i i1
1i
11 1i
i
I
I
I 1
1
l
1
71 i
i
4i
1 1
1 21
I
1
II 51
21
l
1 1
1
1
1 21
i 1
3t l
81 1 1
1
1 1 1 1
1 1
1
2I I
1 1 1 1
l
1 1 1 1 1
1
1|
I
2I l
1
5|
] 1
II II
II
2 II
17.5
1 1 11
II 10 II 20.4
11 I1 II 2 II 15.0
11 11
3 11
17 II
25.76
11 I I II 21 II 18.3
11 I I
II 4 II 18.5
11 11 1 1
II 2 II 19.5
11 11 11
II
1 II
22
11 1 1
II 5 II 24.5
11 1 1
II 9 II 23
11 1 1
5 II 35 II 25.29
11 1 1
II
4 II
21.2
1 1 i t i 1 1 II II
j TOTAL
11
1l|
i ii i
i
32 |
i
28 |
1 22 1
1 10 |
II II
8 I I 112 II 22.55
I 1 i 1 1 1 1 II II
* Includes C 03 aerosol can filler
COT!riDEUT IAL
Subject to Protective Order In
Eos_s_v.
inn., Uo. 90-4037
14th J 'i;ii c 4 ; 1 District Court
Calcasieu Parish, Louisiana
*0 *9 0 0 VW3
(Review date 1 January 1985)
Page 34
TABLE 4C
LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE
MAX POSSIBLE 1
YEAR OF
1
LATENCY PERIOD 1 FIRST EXPOSURE 1
"1 1
LATENCY PERIOD
| ARITHMETIC MEAN
1
1 OF LATENCY PERIODS 1
11
44
I 1939
1 38*
I
1
43
| 1940
1
1
244 m 34.86
1
42 I 1 1 37,21,37.41
|7
!
41 1 2 ! 32,38
|
1
40 1 3 1 38,14,32
|
1
1
4
1 28,11,24,20,24,34,39 |
718 m 26.59 1
I 5 1 27,22,28,29
| 27
1
1 6 I 21,29,31,26,28,15,23,1
1
I
1 30,35***
|
1
36 I 7 1 29,24,29,28
|
1
35 1 8 1 28,24,34
|
1
1 9 1 30,26,20
| 458 m 24.11 I
1 1950
1 26,22,31,19,23,14,33 |
19
1
I 1 1 19,28,17,28
|
1
31 1 2 1 21**,15
I
30
1
3
1 25,22,23,22,20,31
|
1 1
1 4 1 21,21,25,25,21,28***,|
1
1 1 22
|
623 m 21.48
1
I
5
1 22,23,24,14,19,21,27 I
29
1
1
1 27***
1
1
1 6 1 21,12,27***
|
1
25 I 7 1 19,17,15,13,16 |
1
25 1 8 1 18,18,15,17,20 |
1
1 9 1 16,21
| 345 - 16.43 1
1 1960
1 13,18
| 21
1
I 1 1 15,16,16,16,19,18,12 |
1
21 1 2 1 13,18,17,12,17 |
1
20 1 3 1 16,17,19
|
1
1 4 1 16,17
| 139
15.44 1
I 5 1 11 1 6 1 9,18 16 | 7 1 16 15 1 8 1
19 |
I
1
1 1 1 1
19 I 1970 I1
1 1
1
11
1 1 VIOLA
11
11
12
1
10 1 3 1
1 41
1 TOTAL
1 112
11
I 1 MALTONI 1 1 GOODRICH I 2527 - 22.56 1
11
1 112
1
* Cholangiosarcoma ** Aerosol can filler *** US33 and 36; and F15 still alive.
PJST80061400.il/WPX7-2
o rQ^3' L " -r -
,rO i ,,Sfi r.VY'' T^y,
*Svr'
o v`
Y.o-
, ,-v
r r\iv
CMA 004405
(Review dace 1 January 1985)
Page 35
TABLE 4D
LATENCY PERIODS OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND GEOGRAPHICAL
LOCATION
'
MAX POSSIBLE T
YEAR OF
I
LATENCY PERIODS IN
LATENCY PERIOD 1 FIRST EXPOSURE I
11
44 1
1939
1
WESTERN EUROPE
i NORTH AMERICA
1
1 38*
1 ROW I
1
43 1 42 1 41 1
1940
1 2
1
1 37,41
1
1
1 21,37 1 32,38
1 1 1
40 1
3 | 38
1 14,32
1
1 4 I 28
1 11,24,20,24,34,39
1
1 5 I 27
1 22,28,29
1
1
6 I 21,29,31,33
1 26,28,15,23,30,35*** 1
36 1 35 1
1
7 I 29 8 | 28,34 9 | 30,26
1 24,29,28 1 24
1 20
1
T
1
1
1950
I 26,22,31
1 19
1 23,14
1 1 1 19,28
1 17,28
1
31 1
2 I 21**
1 15
1
30 1
1
3 1 25,22 4 | 21,21,25,25
1 23,31 1 21,28***
I 22,20
1 22
1
5 1 22,23,24,27***
1 14,19,21,27
1
1 6 1 21,12
1 27***
1
26 1 25 1
7 I 19,17,15,13
S' 1 18,18
1
1 15
1 16 1 17,20
1 9 1 16,21
1
1
I
1960
1 13,18
I
1
1 1 1 15,16,16,16,19,18 1 12
1
21 1
2 I 13,18,17,17
1 12
1
20 1
3 1 16,17
1 19
1
1 4 1 16
1 17
1
1 5 1 11
1
1
1 6 1 9,18
1
1
16 1
7 I 16
1
1
15 1
81
1
1
1 91
1
1
1 VIOLA 1970
1
1
1
1 11
1 21
1 1
I
1
1
| MALTONI 3
|
|
||
1 TOTAL
1 59
1 45
18
* Cholangiosarcoma ** Aerosol can filler *** US33 and 36; and F15 still alive
PJST80061400,12/WPX7-2
CO
-----T>T-C pO t
,ici
i gM -
r.o COM'Tt -A xiisvis L0'
CMA 006406
(Review dace 1 January 1985)
TABLE 4E
Page 36
PLANT
START UP DATE
LATENCY PERIODS OF ASL CASES
NO OF CASES
AVERAGE LATENCY PERIOD
LOUISVILLE 1 L94Q? 1 12,14,15,19,19,20,24,27,28,28,28,29,29 1
SHAWINIGAN
1 1 31
11
1941? 1 11,12,14,21,22,23,24,24,26,28
S CHARLESTON 1 1939? 24,30,32,32,34,35,37,38,38,39
TROISDORF
1 1954
12,13,16,16,17,18,19,21,23,25
1 1 1
1 1 1
1
I I
1
14 |
1
i
1
10 | i
1
10 |
1
10 I
23.07
20.5 33.9 18
PJST80061400,13/WPX7-2
CMA 00A407
(Review date 1 January 1985)
Page 37
TABLE 4F
LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT
YEAR OF FIRST I
T1
1
EXPOSURE 1939
1 S CHARLESTON 1 LOUISVILLE 1 SHAWINIGAN 1 TROISDORF
! 38
1
1
|
1940
1
11|
1 1 37
I
1 21
1
2 1 32,38
I
1
|
3 1 32
1
! 14
1
4
f 24,34,39
1 20
1 11,24
!
51
1 28,29,27 1 22
1
6 1 30,35 71
1
I 29,28
1 26,28 1 24
1 1
81
91
I 24
1
1 1
1
|
1950
1
1 19
1
1
11
111
21
31
1 15 1 31
1
1 23
1 1
41 51
1 28 1 14,19
1 1
1 21,25 1 23
61
1 1 1 12
71
1 1 1 13
81
11|
91
!1|
1960
1
11 1
11
1
1 12
1 16,16,19,18,
21
1 12
1
1 17
PJST80061400,14/WPX7-2
CMA 006-408
(Review date 1 January 1985)
Page 38
TABLE 4G
PLANT
START-UP DATE | LATENCY PERIOD OF ASL CASES NO OF AVERAGE PERIOD
CASES
11
1 SUNDSVALL I
11
1 3RIGN0UD
11
|1|
1 ST FONS
11
|1I
1 BARRY
11
I1|
1 BURGHAUSEN |
1 11
I NIAGARA |
1945 1950 1939 1948 1933 1947
1
|I 16,19,27,29,31 III 11,16,18,26,30 |I 21,28,29,37,38,27,41,35 l11 9,17,18,28,31,33,18 l11 17,21,22,25 I 15,17,21,23
11
1 5 1 24,4 years
11
1 5 I 20.2
11
1 8 I 31.88
I |
7
1I 22
11
1 4 1 21.25
11
1 4 1 19
1 1
| SPLIT I
1 1
I 1941
1
1 1
I 20,20,22,23
1
11
1T I 4 1 21.25
11
PJST80061400,15/WPX7-2
CO >.o
'J' .'O' ' .
'J. -
\X' c,s t;.^
CMA 006409
(Review date 1 January 1985)
Page 39
TABLE 4H
LATENCY PERIOD OF ASL CASES TABULATED BY YEAR 07 FIRST EXPOSURE AND SPECIFIC PLANT
YEAR OF
1
1 1 11
1 11
FIRST EXPOSURE | SUNDSVALL | BRIGNOUD 1 ST FONS 1 BARRY 1 BURGHAUSEN 1 NIAGARA 1 SPLIT 1
1939
7
1 1 11
11
1940
1
1 1 11
11
11
1
1 37
1
1
11
21
1 1 11
11
31 41
I
1 38
1
1
1 1 11
11
I|
5 I 27*
1
1 11
11
6 1 31 7 1 29
81
91
1 1 1
1 26,30
1 29
1
1 28,34
1
1 1
!
1
1 1 1
1
1 15,23
1 1 1
1 1 1 1
1950
1
1 1 1 31,33 1
1 1 23*
1 1 19
1
1
1 28
1
1 17
1
21
31 41 51
1 1 11
11
1 1 1 1 25 1 1 20
1 1 1 1 21 1 1 22*
1
1
1 1 22
1 21
1
61
1
1 21
1
1
11
71
1 1 1 1 17 1 1
81
1 18
1
II
1 1 20
91
1 16
1
11
11
1960
1
1 1 11
11
11
1 1 11
11
21
1
1
1 18
1
11
31
1
1
1 17
1
11
4 1 16
1
1 11
11
51
1 11
1
11
11
61
1
1
1 18
1
11
* Monomer workers
JS/JH/DSO 16 2 January 1985 PJST80061400,16/WPX7-2
AS'-'
CMrt 006410
TABLE 5
(Review Hate - 1 Jan 1985)
Page 40
Annual Incidence of ASL Cases (Date of Death) by Geographical Area
1955 7
1961
2
4 7
8
9 1970
1 2
3 4 5
6
7
8
9 1980
1 2
1983 1984 TOTAL
1 111
j Western Europe | North America | Rest of World | Annual Total
till
1
1i
1
1
1
l1
1
1 1
1
l1
11
1
1l
1
11
1 1l 1 1 12
|1
1
[1
5 !2
1
1 1
11
15
1
|1 j1
I4 j1
13
16
16
16
|7 )5
i6 I4 j0
11 12
1
4
2
4 3 3
2 -
4
0
1
1
t
1
13 1ii
12
1 11
11II nil to date
1 1 1
| | i
1
1 1
1
1 1
|
2
3 5
8
5
11 11
9
10
5
10
4
1
14
|2 j 58* **
3
1
43**
t nil to date 1 nil to date
18
| | !
7
3 109
| Cumulative
| Total
t
111
iii
13|
14 | |6j
1?
1 12
| 15
1
| j
1 17
1 20
[ 25
1 33
! 38 1 49
1
| |
|
| j
| | Key Events
1
t
1
1
1 1 1
1 1
I Viola
1 1
| Maltonl J Goodrich J
1 60 1 69 1 79
1 84 1 94 1 98
1 99 1106 1109
| | j
t | j
| | j
1
!
1
1
i
T
1
1
1
T T V 9 0 0 VWO
* Includes G03 aerosol can filler but omits It 01 bag extruder
** Does not Include US33, and 36; and F 15.
All still alive.
COriPTTj INITIAL
Subject tc oi;. r Li\. o Order in
Poss_ v.
, '.c. 90-4837
]4tli 1
i
Court
Cri lea o i e;i T-li J ri, Louisiana
(Review date 1 January 1985)
Page 41
TABLE 6
ASL CASE NUMBERS BY YEAR OF DEATH AND GEOGRAPHICAL LOCATIONS (EXCLUDING ITQ1)
I KEY 1 1 EVENTS 1
1 1 1
I
I Viola
1 1
I
1 1 1 1 1 1 1 1 1 1 1 1
iMaltoni I Goodrich
1 1 1
1
I
1
1
1
1
1
1 1 1
1 1
1
1955
7
8
9 1960
1 2
3 4 5
6
7
8
9 1970
1 2
3 4 5
6
7
8
9 1980
1 2
3 4 Total
I WESTERN EUROPE
] FI 1 G1 1 Swl T G2 I Nl,Sw2,UKl,It2 1 G3** 1 G4,G5,UK3 1 F2,F3,G6,G7,G8,It3 1 B1,F4,F5,F6,F7,Sw3 1 F8,F9,G10,GU,G12,Sw4 I F10.FH.G9,G13,G15 I G16.G17 1 F12,F13,UK4,UK5,G18 I UK6, UK7,G19,Sw5,G20,G21 I It4,F14,UK8,G22 1 UK09, lt5, F17, B2 1 UK.10, F16 1 58
1
1
1 NORTH AMERICA
1
1
1 REST OF WORLD
1
1
I Cl
|
1 C2
1 1 1 1
11
11
1
I US8 I C3
1 1 1
1
1 US5
1
1
1 Cz2
1
11
11
1 C4,C5,US4,US7,US10 1
I US12.US16 1 USll 1 C6.US2
1
--!-----------------------------------------------------------,---------------------------------------------------------
1 C7
1
1 C8,US1,US3,US23 1 C9.US13
1 Yl,Y2,C2l
I US6.US9.US18.US26
1 Japl
1 US19.US20.US22, 1 C10.US21.US24*
1 Jap2,Y3
1
I US27.US28
I Y4
11
1I | US17, US29, US30, US32
1
1 US31
1 1
I US35, US34, US38
1 US37 | 43***
!
1
I8
11
* Choiangiosarcoma ** Aerosol can filler *** Does not Include US33, and 36; and FI5.
All still alive.
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CMA 006412
(Review date 1 January 1985)
Page 42
TABLE 7
ASL CASE NUMBERS BY TEAR OF FIRST EXPOSURE AND GEOGRAPHICAL LOCATION (EXCLUDING IT01)
KEY | EVENTS I
1 n------------------------------------ 1
| WESTERN EUROPE
I NORTH AMERICA
| REST OF WORLDj
11
1
1
11
1 1939 1
1
I US24*
1 1
1 40 1
I 1 |Frll,Frl6
1 21
1 3 | Frl4
1
1 C3.US27 I US13 US29 1 C2.US19
1
1
I
1
1 4 IUK1
1 C1,C5,US5,US7,US28,US35 1
1 5 | Sw2
I C4,US3,US9
1
1 6 |Frl,Fr3,Sw4
1 C7,C9,US8.US11,US21,US31|
1 7 | Sw3 1 8 |Fr9, Frl7 1 9 |Frl2,Fr4
I C6,US22,US26 I US1 I US12
1
I
1
1 50 |Fr7,Nl,UK8,UK9
I US16
1Y2, Cz2
1 1 |Swl,UK5
I US10, US32
1
1 2 |G3**
I US4
1
1 3 |G15,It3
| CIO, US37
Uapl.Yl
1 4 |G7,G8,UK4,G19
1 US18.US33***
|Y3
1 5 |Gll,G16,G18, Frl5
I US2,US17,US20,US34
1
I 6 IFR10.G1
| US36***
1
1 7 |Fr8,G4>It2,G2
1
iCzl
1 8 |Fr6,Bl
I US23
|Jap2,Y4
1 9 |Fr2,Xt4
1
1
1 60 IG5.G13
1
1
1 1 |G9,G10,G12,G17,G20,G22| C8
1
1 2 |G6,UK6,G21,B2
1 US6
1
1 3 1Frl3, UK7
I US38
1
1 4 | Sw5
1 US30
1
1 5 1 Fr5
1
1
1 6 |UK3, UK10
1
1
1 7 | It5
1
1
1 81
1 91 Viola | >0 1
1 1
I
1
1
1
1 11
1
Y
1 21
Maltoni |
31
11
1 Total |59
1
1
1
1 45
1
1"
l 18
1 11
* Cholangiosarcoma ** Aerosol can filler *** US33 and 36; and Fr 15 are still alive.
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CMA 006*413
(Review date 1 Jamary 1985)
TABLE 8
Page 43
WESTERN EUROPE FVC PRODUCERS - START-UP DATES va ASL GASES (CHTITING G03)
r-
cw
Hi o V <?>
1:
3 o o
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EH I --! t--. ; --a
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oi
ISTART-UPl ODUNHer MJE | COMPANY NttE 1
LOCATION
ASL CASE NUMHR 1
YEAR CF
|
1 YEAR
11
1 1st Exposure |
1 193T"" West Germany IBASF
ILudwigshafen
11
I 1933 West Germany IWacker
iBurghausen
04,07,11,15
157,54,55,53
|
| 1938 Italy | 1939 France
iMontecatini lAcna IRhone Poulenc |St Fans
11
103,09,10,11,14, 146,48,56,41,43, |
11
15,16,17
155,41,48
|
| 1940 United Kingdan|ICI | 1940 United Kingdom|ICI
|Runcorn iHUJhouse
01,04
1
14434
1
|
1 1945 Sweden
IKemanord
I Sundsvall(Stockvlk) 01,02,03,04,05 151,45,47,46,64 |
Switzerland iLonza
iSlns
| 1946 France
iRhone-Poulenc iRousillan
01
1
146
1
|
| 1947 Italy
[Montedison
IPorto Marghera
02
157
|
| 1948 United Kingdcm|BP Chetn
1Barry
03,05,06,07,08,09166,51,62.63,50,50 |
10 66. |
West Germany IHuls
|Marl
09,10
161.61
|
| 1949 Belgian
ISolvic
iJemeppe
01,02
158,62
|
| 1950 France
iPuk
IBrlgnoud
02,04,05,06,12 159,49,63,58,49 |
France
IRhone-Poulenc |St Auban
07
150 --------------------1
Holland Norway
I Shell | Norsk
iPemis iHeroya
01
1
150
1
|
| 1951 | 1952 | 1953
Italy Italy Austria
IMeritedi son
[Montedison lHalvic
I Brindisi
iTerni IHallaln
1
1 1 """
1
1 1
France
ISolvic
iThvasc
08,13
157,63
|
Italy
ISolvic
1 Ferrara
03
153
|
Spain
IRLo Rodano
iHemani
11
United Kingdom|BIP
lAyc.llffe
11
West Germany iHoechst
iGendorf
18
155
|
| 1954 West Germany [Dynamit
iTroiadorf
01,02,08,12,16, 156,57,54,61,55,61,1
1
11
17,19,20,21.22 154,61,62,61
I
| 1955 1 1956
1 1958 1 1960
Spain Spain
West Germany Italy
1Monsanto Iberla|Mxizon
iCaiaaa
iSablnanlgo
iHlspavic
llbirelavega
ISolvay
iRhelnberg
IS C Ravenna 1Ravenna
04
1 1 1
1
159
1 1 1
1
|
1 1960 West Germany ILonza
iWalddut
106,13
162,60
|
| 1962 Portugal | 1965 France
ICires
1Oporto
IRhone-Poulenc iMontluron
11 11
Italy
iPozzl
West Germany iWacker
| 1966 West Germany IHoechst
iFerrandina 1Cologne |Knapsack(Frankurt) 05*
1
1
T&'
1
1 1
1 196> France
IAIO Chimie
iBalan
11
Spain
|Rio Rodano
Greece
lEsso Pappas
| 1968 Belgian
iBadiphil
| 1969 United Kingdom iVinatez
Italy
Ipinrianra
(Miranda de Ebro IDiavata Salonika |Antwerp
iStaveley 1 Cagliari Sanllm
1 1 1 1 1 "
1 1 1 1 1
| 1970 Italy
ISIR
United KingdomllCI
1 Porto Torres Sar iRuncom
11
!1
| 1971 Italy Spain
|S C Ravenna IHlspavic
iRavenoa iMartorell
1 1"
1 1
Sweden
IKemanord
IStenungsund
1i
United KingdomjBP Chan
1 1972 Finland
iPekema
iBaglan Bay ISvartback
>1 CnunAn fU\rU\jLOAM1 xAt
Holland I 1976 France
|DM
iBeek Limburg
|Soc Art D'vinyl IMfudngarbe
1i ii
| 1977 Spain
1Monsanto Iberia | Tarragona
ii
* Laboratory worker In Research Department
** Pinsec, Mira Venice, case not included. (It 05) dje not knowing start up date of the Plant.
PJST80061400,3/WPX7-2
(Review date l January 1985)
Page 44
TABLE 9
USA PVC PRODUCERS - START-UP DATES vs ASL CASES
START-UP| COMPANY NAME
I LOCATION
1 ASL CASE 1 YEAR OF
YEAR 1
1939? l*ucc
1
I S Charleston
! NUMBER
1 1st EXPOSURE
107,13,19,21,24 ,144,42,43,46,39,
I 1940? |*BFG
1
1 Louisville
127,28,29,31,35 141,44,42,46,44 101,02,03,04,05 ,148,55,45,52,44,
1 1 106,09,16,17,22 , 162,45,50,55,47,
1946? 1947 1948
1
|*UCC | Goodyear 1 Firestone
1
I Texas City | Niagara Falls 1 Pottstown
126,33,34,37
1
108,10,11,20
112
147,54,55,53
! 146,51,46,55 149
| Uniroyal
1
| Painesville I (closed 1975)
r
1
1 1
1950 | Monsanto
1 Springfield
i 32
151
1952 | Dow 1 BFG
I Midland I Avon Lake
1
118
1
154
1953 1954 1956
| Diamond I General Tire | Air Products
| Deer Park I Ashtabula 1 Pensacola
1
f 36
1
1
156 T
| Atlantic Refining 1 Brooklyn
I Borden
| Leominster
1 1
1 1
| Conoco 1 BFG
I Hebronville (Closed 1975)
I Niagara
1
1 1
I Great American j Plastics
| Fitchburg I (Closed 1983)
123
1
158
1
! Hooker
| Hicksville
I
1
1957
I Pantasote 1 Atlantic Tubing 1 Tenneco
I Passaic
| Cranston j Flemington NJ
1
1
I 30
1 1
159
1958 I Keysor Century 1960 | BFG
1 Saugus, Cal | Watson, Cal
1 1
1
1-------------------------------
I Air Products
I Calvert City
138
1
1962
1
1 Borden 1 Tenneco
1 (closed March 1982 Re-opened October 1983)
j Illiopolis
1
1
| Burlington NJ
1
1-------------------------------
1963 I Conoco
I Aberdeen, Miss
1
1
I Stauffer
I Long Beach, Cal 1
1
1965 1966
I Conoco 1 Ethyl | Diamond
I Assonet, Mass I Baton Rouge | Delaware City
I
1 1
1 1
1-------------------------------
I General Tire/Pantas| Mt Pleasant W Va I(Closed 1983) 1
I BFG | Stauffer
| Henry, 111 ) Delaware City
1 1
1
1-------------------------------
1967 1 Allied
| Painesville, 0 ** 1
1
1
1 (sold to Robintech)
1
1 Hooker 1968 1 Firestone
1 Burlington NJ 1 Perryville
1 1
1 1
1969 I BFG
| Pedrickton NJ
1
1
| Goodyear
I Plaquemine
1
1
1 Olin
I Assonet, Mass (Closed 1975)
1
1 (Formerly Conoco)I
11
1971 i Conoco
| Oklahoma City
1
1
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CMA 00641
TABLE 9 (Continued)
Page 45
USA PVC PRODUCERS - START-UP DATES va ASL CASES
|START-UP I I YEAR | 1972 1 | 1973 1
|
COMPANY NAME
Nat Starch Borden Robintech **
| 1974 1 Atlantic Tubing 1 Shintech
1 1975 I Certain-teed i Georgia Pacific I Tenneco
I 1979 I Firestone
| LOCATION
1
1 Meredosia, 111 1 Springfield I Painesville, 0 | (sold to Georgia | Pacific who I converted to 1 polystyrene) I Cranston RI I Freeport, Tex | Lake Charles | Plaquemine, La | Pasadena, Tex 1 Plaquemine
1 1
ASL CASE NUMBER
I YEAR OF
I
1 1st EXPOSURE |
1
1
!
1
1
1
1
1
1
1
1
1
1
* My databank has no information on UCC before 1946 or BFG before 1950
** Refer to same plant at Painesville. Allied plant never operated again for PVC after it was sold to Robintech.
NB Some of the plants in this list were closed down, some have changed ownership over the years
PJST80061400,5/WPX7-2
CMA OOd.416
1
(Review date l January 1985)
Page 46
TABLE 10
CANADIAN PVC PRODUCERS - START-UP DATES vs ASL CASES
|START-UP 1
COMPANY NAME
I LOCATION
1 ASL CASE 1 YEAR OF
1 YEAR
1
1 NUMBER
1 1st EXPOSURE
1 1 1-------------------------------
| 1943 | Goodrich 1(1941?)
1 Shawlnigan
1
101,02,03,04,05 144,43,41,45,44, 106,07,08,09,10 147,46,61,46,53
1 11
1 1951 I Monsanto*
1
I La Salle
1.
1 1
1 11
I 1957 I Goodrich
1
| Welland
1 1
1 1
1 I1
| 1966 1 Esso
1
| Sarnia
1 1
1 1
1 11
11
| 1979 | Diamond Shamrock Alb ! Fort Saskatchewan 1
1 1
1 11
* Terminated 1975
PJST80061400,6/WPX7-2
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CMA 006417
.Review date l January 1985)
Page 47
TABLE 11
EASTERN BLOC PVC FACTORIES - START-OP PATES vs ASL CASES
|START-UP | COUNTRY NAME 1 COMPANY NAME
1 YEAR 1
1
iPre 1939 lEast Germany 1 State Company
1 1941 I Russia
1 State Comps
1 1950 (Yugoslavia
Uugo Vinil
1 1951 I Czechoslovakia I State Comps
1 1955 lEast Germany 1 State Comps
1 1956 I Rumania
1 State Comps
| 1957 I Poland
1 State Comps
I Rumania
I State Comps
11
1 1958 I Rumania
I State Comps
1 1959 1 Hungary
I State Comps
I 1961 I Rumania
1 State Comps
| 1963 IYugoslavia
lOhis
1 1965 t Bulgaria
(State Comps
1 1967 I Poland
1 State Comps
| 1969 I Russia
I State Comps
| 1970 I Rumania
1 State Comps
I Russia
I State Comps
I 1972 (Yugoslavia
iVinilplastika
| 1975 1 Czechoslovakia 1 State Comps
I Russia
I State Comps
I 1976 (Yugoslavia
iHip
1 1977 I Rumania
I State Comps
| LOCATION
1
I Schopau I Vladimir et al (Split (Novaky IBltterfeldt IIcechim lOsweicim (Dwory) iTimaveni 1 Turda iRisnov iBerente Borsod iBorzesti
(Skopje (Varna ITarnow iDjerjinsk iRlmnicu Vilcea (Volgograd I Zadar iNeratovice iKalush Area IPancevo IRimnlcu Vilcea
ASL CASE NUMBER
01,02,03.04
01,02
I YEAR OF 1 1st Exposure
1 1
153,50,54,48 157,50 I--------------------------------~1---------------------------------
1 1 1 1 1 1
1 1
1
1
1
rr~
i
i
i
i
i
PJST80061400,7/WPX7-2
CMA 006418
(Review date 1 January 1985)
Page 48
TABLE 12
JAPANESE PVC PRODUCERS - START-UP DATES vs ASL CASES
|START-OP I
COMPANY NAME
| YEAR 1
| 1950 I Chisso Corp
| Kanegafuchi Kag
1 Tekkosha
I 1951 I Mitsui Toatsu
I 1952 I Mitsubishi Mon
| Sumitomo Kag
I 1951 | Denki Kagaku
| Nippon Zeon
1 Toa Gosei
I 1955 | Ryo-Nichi
| 1956 I Nippon Zeon
1 Nlsshin Kagaku
| 1957 I Kureha Kasei
I Shlnetsu Kag
I 1960 | Denki Kagaku
| Kanegafuchi Kag
1 1964 I Chisso Corp
1 1966 | Tokuyama Seksui
I 1967 1 San Arrow Kagak
I Sumitomo Kag
I 1968 I Ryo-Nichi
1 Shlnetsu Kag
1 1970 1 Chisso Corp
| Denki Kagaku
| Kanegafuchi Kag j Kawasaki Yukl
I Mitsui Toatsu | Nissan Kagaku | Shlnetsu Kag 1 1971 | Tekkosha 1 1973 I Asahl Glass | 1974 | Toyo Soda
1
1 1975 I Central Kagaku I Toyo Soda
| 1977 I Unknown
| LOCATION
1
I Minamata | Osaka 1 Sakata I Nagoya I Yokkaichi I Klkumoto I Shibukawa | Kambara 1 Tckushima 1 Uozu 1 Takoaka ] Takeo I Nishiki | Naoetsu 1 Ohml I Takasago | Chiba I Tokuyama I Tokuyama 1 Chiba ] Mizushima I Tokuyama I Mizushima 1 Goi (Chiba) | Kashlma I Kawasaki 1 Sakai 1 Chiba I Kashlma | Yokkaichi 1 Hayatsuki I Sakata j Yokkaishl
1 Kawasaki | Yokkaichi I Kashlma
I ASL CASE 1 NUMBER
1 1 1
I 01, 02
1 1 1 1 1 1 1 1
I
1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1
1
1 1 1 1 1 1
1 YEAR OF 1 1st EXPOSURE ~i
1 1
1 53, 58
1 1
I
1 1 1
1 1 1 1
1
1
1 1
1 1 1
I
1 1 1 1 1 1 1 1 1 1 1 1 1 1
i
l
PJST80061400.8/WPX7-2
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(Review date 1 January 1985)
Page 49
TABLE 13
SOUTH AND CENTRAL AMERICAN PVC PRODUCERS
START-UP
COMPANY NAME
YEAR
1953 I Monsanto Mexica
1954 1 Policyd
1955 i Geon Do Brazil
1956 Elchlor
1960 Electrochlor
Viplastic
1961
Indupa
1965
PET Columbiana
"1955
Carboro De Col
"1 LOCATION
1 | Lecherla (Mexico) 1 Mexico City (Mexico) I Sao Paulo (Brazil) | Sao Caetano (Brazil) ICapitan Bermudez(Argentina) 1 Mendoz (Argentina) 1 Cinco Saltos (Argentina) 1 Cartagena (Colombia)
1 Medellin (Colombia)
1 3 967 1 1967
1968 1970
1971 1975 1976 1977 "1578
1979
SOC Paramanga Plasticos Omega Primex Policasa Petro Dow Polimeros Mex i Rico Chemicals i Petroplas | Indust Resistoc Huls Brasil Polychem
1 Policyd 1 PET Camacari
1 Faramonga (Peru) I Mexico
| Puebla (Mexico)
| Managua (Nicaragua) j Conception (Chile) j St Martin Puebla (Mexico)
I Guyanilla (Puerto Rico) I EL Tablazo (Venezuela)
I Tlazeala (Mexico)
| Cubato (Brazil) j El Salvador
1 I
I Coatzacoalcos (Mexico)
I
| Camacari Bahia (Brazil) 1
ASL CASE NUMBER
YEAR OF
|
1st EXPOSURE 1
11 11
I1 11
PJST8006 L400,9/WPX7-2
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CA 006420