Document B82ZBwbYz3Je9822Jr97kjew8

CONTACT REPORT C O N F ID E N T IA L Under S ecrecy A greem ent w ith C aliforn ia R esea rch ' D ate: January 19, 1959 P lace: C alifornia R esea rch C orporation, 200 Bush S treet, San F ra n cisco , C alifornia ' P resen t: J. C ooley, J, M acGregor, . , F . Kavanagh, H. M cPherson, M, Baruch, D r. C urtiss, M r, J, Spence, H,, S ig w o r th , F , Sitek R. Rogers D r, R. Kehoe, R. K. S cales, H, J, G ibson, C alifornia R esearch "" " ." . "" "" Standard O il Co. (C a l.) M edical "" " " " , F E D , W estern O perations " ", M arketing " ", M fg. K ettering L ab oratory E thyl C orporation "" SUBJECT: M ore V olatile Lead A lkyls John C oo ley opened the m eeting by stating that they would p refer to d isc u ss : fir s t the m ed ica l a sp ects of the m ore v o la tile a lk y ls. D r. K ehoe then started to review h is background in this a rea . He em p h asized that w hile th ere w ere d efin ite d iffe r e n c e s am ong the, s e v e r a l m e th y l-e th y l a lk y ls in so fa r as absolute to x icity is con cerned, he fe e ls that th ese d ifferen ces a re sm a ll r e la tiv e to the p ro b lem s im p o sed by the d iffe r e n c e s in v o la tility of the com pounds. V o la tility is im portant in that it a ffects the exp osu re le v e l of in d ivid u als, and hence the rate of accu m u lation of P b . He stated that 75 m icro g ra m s Pb p er cubic m eter is the m axim um to w hich a m an should be exp osed on a continuous b a s is , and is the m axim um in our p lan ts, He em p h asized that organ ic and in organ ic lead w ere quite d ifferen t in their e ffe c ts . He a g reed to p ro v id e C a lifo rn ia R e se a r c h w ith certa in of h is u n published data on to x icity of the m eth y l-eth y l alk yls for different typ es of exposure. A v ery w ide v a riety of q u estion s w as asked of D r. K ehoe. John C ooley ` pointed out that they could not ju stify a la r g e -sc a le exp erim en tal program if fa cto rs now known would prohibit the u se of m ore v o la tile lead com pounds. He w anted to know w hether a long to x ic ity study w ould be req u ired , after exp osu re le v e l w as d eterm in ed , b efo re a m ore v o la tile com pound could be u sed c o m m erc ia lly . D r. K ehoe em p h a sized that know ledge now availab le tfg 0004028 CONTACT REPORT Page 2 did not p erm it statin g the allow ab le le v e l of v o la tility . He sa id that if we found the le a d -in -a ir ra tio , T M L /T E L , to be 1 to I it w as obvious there w ould be no p ro b lem , if 2 to 1 th ere s till w ould be no co n cern , if 40 to 1 h e'd sa y that u se of TM L w a s im p o s s ib le . He sta ted a ra tio o f 10 or le s s would not clea r TML but would o ffer hope of co m m erc ia l u se . (T hese com m en ts apply to the other a lk y ls and m ix tu res, a ls o . ) D isc u ssio n indicated that g r e a te st exp osu re would be exp ected at truck and tank ca r loading ra ck s, and se r v ic e station or fle e t d isp en sin g job s. C arburetor serv ic in g jobs w ere recogn ized as being p o ssib ly hazardous. C on sid erab le tim e w as devoted to d iscu ssio n of field testin g of exposure le v e l. M r. R ogers pointed out that th eir B a k ersfield refin e ry would be the b e st p lace to do.the job. H ow ever, p rem iu m g a so lin e alone would require the Pb equivalent of 216, 000# TEL for a 3-m onth test period. T reatin g regu lar would add another 70, 000 pounds. It w as pointed out th at a. q u a n tity s u c h a s th is Was u t t e r ly im p r a c t i c a l fo r u s to m a k e . D r 's . K ehoe and Cixrtis s in d icated they w ould be m uch con cern ed about a te st p rogram of th is s iz e . D isc u ssio n then cen tered on how to do a s m a lle r -s c a le te s t. F in a lly , it w as agreed that m ean s would be found to study lead le v e ls w ith TEL at C a lifo rn ia 's refin e ry loading ra ck s. R ela tiv e ex p o su re due to T EL and TM L in the Y ellow Cab fle e t r e fu e l ing station would be studied. (C aliforn ia R esea rch h as, or sh o rtly w ill r e c e iv e from com p etition, the 500-pound lot of TML on which we w ere ask ed to bid. T his should not be d isc u sse d w ith C a lifo rn ia R e s e a r c h personnel. ) T h ere w as co n sid era b le d isc u ssio n am ong Dr's. K ehoe and C u rtiss and M r. S p en ce a s to w heth er stu d ies sh ould be b a sed on lead* in ~ a ir or on u r in a r y e x c r e tio n or both. It a p p ea rs C a lifo r n ia w ill u se both. It ap p ears that we at E thyl can exp ect to lea rn the r e su lts of their study but w ill have no part of it. M r. C ooley w as m o st em phatic in stating that he w anted to u se TM L in th e se s tu d ie s. The people from R ichm ond and M e s s r s . S ca les and G ibson com pared n o tes on an tiknock and le a d -in -a ir stu d ie s. C a lifo rn ia R e se a r c h data on rela tiv e le a d -in -a ir w ith TML and T E L a g ree w ell with ours w here we h ave com p arab le stu d ie s. (C o p ies of th eir data have b een su pp lied to M e s s r s , H e sselb e rg , H irsch ler, and G ibson. ) G iven to C aliforn ia R esearch were: 1. E vaporation o f Lead A lk yls - H. J. G ibson - January 15, 1959, su m m arizin g data obtained under D . A . H irsch ler's d ir e c tio n 2. E vaporation of Lead A lkyls - H. A . B eatty - 1 9 5 8 3. Lab. A ntiknock E valuation of TM L, M A -250, M A -500, M A -750, and T E L in F in ish e d G a so lin es - dated 1 / 1 5 / 5 9 prepared by M aassen and B u erstetta. CONTACT REPORT Pa T h ey w ere told o f our stu d ie s of an tik n ock d e str u c tio n w ith sulfur and phosphorus. T his w as a m ost pleasant and in form ative m eetin g. H JG /dl C opie s to: ,'D. M. Guy . Ho E . H e s s e lb e r g B. A. H irschler R. V. K erley w . G. L ovell Wo B . L ig e tt . R. K. S cales R. A. Kehoe 3 G. F . K irby P i A , M cK im P,, W eim er J,, K o e h n le G il Yvra y H arold G ibson t f e 0004030