Document B5d2qm5y5ze9axykZGoZrMLE

CONTENTS Bibliographic :'nformation............................................11 Ordering reports..........................................................** Prices of reports....................... 111 Sample citation........................................................... About NTIS................................................................ iv About NTISearches.................................................... v Citations........................................................ 1 BIBLIOGRAPHIC DATA SHEET 4 I * li` jml Sufi; Toxicity of Vinyl Chloride (A Biol io-_> rapliv with Absr me: - j 'col tor: Pernel) W. Crocker! 9. i i;i::jii m ' inr in I ' ` ' National Tr'chn icq ! Inrorr.; t ion 5285 Port Royal Read Sprinofielo, 7 in inia 22181 l 2, spon\or.rfcl ` V * r c wo N tm/* tr.-: Same 15. i`upp.rmcni.fv Note* Supersedes NT IS/PS -77 /03C5 and NT IS /PS-7 A /f JI 07 ?!Ti-7/ ii-M2 M.-iv. NTs Iffthll, * N ' .1 M 1 ! IJ 1" o- I ;n : r .i C' < . '.i;!! N .fir jI 1 nVfr'il !A J'CfioiJ IQfiO - Apr, . 14, 7S Ui. Abstract: Research is cited on the health hazards from exposure to vinyl chloride and vinyl chloride resins. Studies are included on the epidemiology of industrial and public exposures to the compound and its degradation and combustion products. (Tliis updated bibliography contains 79 abstracts, 10 of which are new entries to the previous edition. ) R&S 025408 Copyright Warning Portions of this publication bearing a copyright natict are copyrighted, international Coc vri^ftt, < National Technical lnl<Kmsu>tin IQ7R unfit)/ th pfQvm<oi'3 of trie Univeri.ti Cop yfight Convpntujit Uriitoo States copyright ii no. .titerted under me United States Copf/igni Low. lulu 1", Un>tad HiAiti Coda RrPPOOUCfO NATIONAL TECHNICAL 17 NT IS t' i r IJ (r u U p 57Y, 6S 13. Avot!jr>iht> htatemtrr.i INFORMATION SERVICE > 1 : stPusr.iiM or rpvMtRCE *< LIO *A 19, Nf J U( I| V < . I4 5 v R f port) I h1s 21. .No. or __ ________ JJ^UL^IF i.V. ^u. Vw.'iiv i Thi^ 22. Pncc rciuu HTIHj |H(Y, o; tjl lnouk^.d to an'-i v\ni-NK'.a r^ri.^irn-n .'Hlb M'-M MAY I1K Khf'ROUl.'C KD S28.00 uicow-&c aiat-^Ta USER INFORMATION Ordering Reports Most documents cited in this Published Search are available directly from N TIS. When NTIS does not sell a document, the abstract will note the source front which the document may be obtained. An NTIS order form (see last page) is included for your convenience m ordering documents. Prices of Reports Please refer to the price schedule inserted in this Published Search to obtain the correct paper copy and microfiche prices of the reports you order. Printed prices in the abstracts have been susperseded in most cases. .Sample Citation from the NTIS Data Base ICompilation of State Data for flight Selected oxk Substances, Voiumc J Mitre Corp . McLean, N> \ *l.ns ironrnentnl protection Agents. kk ishmyton. DC Oll'ice of Toxic Substances (402-lMi Title Corporate Author Sponsoring Agency rept AU'l HOR Robert*. Lluaheth, Spewuk. R . Striker, S.. Irjces. S C>W5r4 I'lD t>rT Obi* 57 Y*. $7n. 6K* USGRDKTbOb Sep 75 Ib5p*----------------------------- Rl-PT SO \UTRl,*75*5:.VoM CONTRACT l:PA-bft*0l 29.U MONITOR F.PA 560-7.75 00M Paper cops also jvadable in set ol 5 reports as PB-2JX r*dU-Sl`T. PCS.'AOO MiSTRAC'l In June W74, toxtc substances djta in the L S \xere collected and analv *rd in 20 key suicv I his report describes that ellort and discusses the amount, ts pe and uscIlI.-.C'S of the data and toxic substances monitoring capabilities ot me stale acencics contracted DESCRIPTORS 'htncnomenlal sursess, States 11. ruled Slates). Monitors. T'oxkoIo^ Arsenic, lierMiium. Cadm.um, tsamdes. lead iMetah. Mercurs i.Mciul). (Marine jronutii compounds. Data acqujstion. Datj proicssintt. ^ater pollution. Air pollution, t hemical compounds I DhN Tl f-1 LRS "Tore apt.,ns, Hiphcnsl Sine attent-ies nTISH'OATS hhO 1ST MIS Prices PC AO* Ml VII ------------------------------------------------------------ - --------Keywords 1---------"--------------------------------------------------- NTIS Subject Categories Pages in Report Report Date Order Number Microfiche Price Code Paper Copy Price code R&S 025409 ABOUT NT IS The National Technical Information Service (NTIS) of the U.S. Department ol'Commerce is the central source for the public sale of documents resulting from government-sponsored research and prepared by federal agencies, their contractors or grantees, or hy special technology groups. NTIS also is a central source for federally generated machine processable data files. As one of the world's leading processors of specialized information. NTIS ships about 20,000 information products daily, supplying the public with approximately 4,000,000 documents and microforms annually. Its collection exceeds 1,000,000 documents, ail ol which are available for sale. NTIS is an atypical government agency because it operates much like a business, It is obligated by Title IN U.S. Code I 151-7, to recover us costs from sales and therefore must charge for its products and services, NTIS provides various types of services to meet the needs ol its diverse user population. Through the use ol these services one may obtain abstracts of reports m the NTIS collection and. after determining from the abstracts which reports are of interest, order the reports in paper copy or as microfiche. Services provided by NTIS include a standing order microfiche service (SR1M) that automatically provides subscribers with the full texts of research reports selected to satisfy in dividual requirements; an all-inclusive biweekly journal (Government Reports Announce ments & Inde.xf published for librarians, technical information specialists, and those requiring summaries categorized in a single volume with an index; and newsletters published in 26 categories of specialized interest. The NTIS Bibliographic Data File on magnetic tape is available for lease. Information concerning the products and services offered by NTIS may be obtained by re questing brochure number NTIS-PR-154 R&S 025410 ABOUT NTISEARCHES NTISearches are online information products developed from the NTIS data base which contains more than 600.000 document/data records of government sponsored research. NTIS provides two types of NTISearches; Published Searches and customized Online Searches. Published Searches are bibliographies with abstracts that provide a quick, inexpensive way to determine w hich reports in the NTIS data base are of special interest to a user. The Searches are prepared by NTIS information specialists and are available in many topic areas; they are updated at regular intervals and cost S28.00 each. The cost of a Published Search will be credited toward the cost of a customized Online search in the event the Published Search does not meet ones needs. A complete list of current Published Searches is available free by requesting brochure number NTIS-PR-186. Customized Online Searches are bibliographies with abstracts that are prepared to meet a special information need which is not met by a Published Search. They may be initiated either by writing to NTIS or by calling the Online Search telephone number (703) 557-4640 to discuss specific areas of interest with an information specialist. The cost of a customized Online Search is as follows; Up to 100 technical report summaries 101 to 200 technical report summaries 201 to 300 technical report summaries 301 to 400 technical report summaries 401 to 500 technical report summaries More than 500 technical report summaries North American price All others S100 125 150 175 200 S125 160 190 220 250 Negotiated R&S 025411 v R&S 025412 abstract: 'pht ?pori.'.l Listing of Current Career Eesairch Frog-nets is a s=r'/:c i of the Ir* er na * icna 1 Career Research Data Ear k (TCELE) t.roqrea of * 1 a Maticr.al Cancer Trs + it u *=. "ac*- listir.n cca*air.s deocr: r:*ior.r ir.cluuss research areas ir: Cancer risk as.~ccia.~ed vi*h, cccj na* icna I 'xrosure to specific organic chemicals: carcircc^ric *ifac"s arc "`--a be ] isir cf a?c dyes, irviamines and ether i.sccyclic aromatic hydrocarbon d.cr i va* i v=s ir animal ncri?l,j; ca rein coc r. ici r y sr.'i o-tatclisn' cf aliphatic hydrocarbon derivatives ir. animal nodel s : caro ir.oc =r icit v *s`.itg of ethylene halides ir.'l oth = r *r aliphatic hai eh yd recarhor. dr i v at iyop ; carcineg~nici*v a r.ri 3i**aroli S3 of hs-crccyclic compounds in animal models; ar. 1 broad programs, a f J oth-;r studies cr. chemical carci rege n 3 i ir aria'll mc^is. Cescriptors; * K alignart neoplasms, `Ens^arch prci^cts, `Industrial medicine, ^Organic compounds. Carcinogens, Metabolism, Vinyl chloric-. Chlcrchydrccarfccr.s, Aromatic hyd rcca :L cr.s, Azo : ys Ar v 1 amir.ss , Aliphatic h ydrccarbons, Halides, Ethylor.es, Ha 1 chvi rcca rbcr.s , M^terccvclic comrour.ds Td=-r.*iiars: `Listings, `Cancer, nodical rasearch, `carcinogenesis. Health risks, Ether/Ch lerem a*by 1, nusnimic? VTIStE/C/2<56-0<'u 'JTIS Frieze: FC AO 3/ME AM R&S 025413 r 12 r r -1 .cu1- Cc::cri*iir., 'Tr.:cn City, t- la* ior.1 s* . for Occura zi or til Safa* v and 'Hal- h. ch->. , (';t-.r 7 ht) ` H C ? : T C 4. i s h u r y, 3 t a n 1 - 1 A. Er 3c2 l Fid: fj, ftC, 5 "/IJ, 57 { , 9UC, 6Hr, , 9 A n ? AT"a a -j C fur Pe o ~ 1 ! I No: >T T 0 TH" t r-KH E-7 6o-3nr , wori-or : 1H ls*ract : A h c a 1 * h h a 7 a r d aval uat ion. d a t = r m ina * i cn perf c r a e d b v NTCSM ^n duly 12 and 12, 1976, at t he Hardy Civision c f + Y.*= Che Her Glebe for nor at icr. in !'nion City, Indiana revealed `hat employes vorkinq v i * h c r rta: the polyvinyl chloride ir.i3ct:rr. molcinq o:ocsj arr not ''ypOFvt to rie t <=c`a 11 s levels cf vinyl chloride vapors. 'he 1 "rfi i iri ra *icn. was based cr. direct n>ea ureme n - s a nri collected air nT>l*s taken curing fccth normal and purcir.o operations of ?.n rr.]cc*,ir7 meld: r.c machine. Hydrogen chloride, a thermal decomposition r.ioduct of polyvinyl chloride, was else rot .1- tnet "d iurir.n th ; infection meidir.c operation. r'cscr iptors: `Thermoplast ic resins, *Ma7.ardcus satsrials , "Industrial medicine, *Er.vi rcraer. tal surveys, "Virvl ehleri<:=>, *Hydrcqer chloride, "Pclvvinyl chloride, "Plastics industry. Toxicity, industrial hygi0rc, Toxicology, Evaluation, In.speo tion., Air pollution, = -ccmmer.daticr.s, Criteria, Vapors, r.olciinq techniques, Interviews, Ch lerchydrocarbons, vinyl resir.s JO fio C0 croon u T u f* n t i t i ? r s: * En vircrmertal health. Air samolir.g, Toxic substances, o<~cu rat icnal safety ar.d health, "Air pollution si facts (Humans) , S he 1 It r-Globs Corporation, union, city (Indiana) , '!TISHrvr>E d Pf-273 E 25/fiST >'TtS Prices: FC AC2/MF ACT .' ...........  * sb u rg h M ni v Fa 'J ^ Z 2 ^ 1 > .'ef'.tr's thesis ."'"HC?: s-ha*a, k , ; j* c:i 1:, j. h.: AI a r;c , y. Fid: 111, 6T, 71C, f 7 Y 0 F ,\ T 7 8 C 3 U Mcv 7 7 Uf-c $ ?'n* M2; 5ET7C-:tf'r-77-1('7,T?-l Contract: NOTM u-77-c-r 3 K tcritcr: 18 *bs*ract: The toxicity of thermal decc m pcs i * ic r. products ( : n air) c f vg; ncl y ? r y loxy p ! cs p h ezar.a and pciv f 1 ucrc.*. 1 k cx y thost>ha oar & was evaluated ir terms cf heir sen.tcty irritation so: ir~ index (S.I.S . T .) u r i r o nic"' 'o j.sccf air. certain advene3 rhysiclcmcnl effects. T he results src compared with sene other polymeric ma'^rials {cf commercial ir.-erejst) tha* hav = alre ady leer ir.es* iga * ed el5?''ha: con pa risen- .31 these data shows *** "hi hazard r a * i r. a tor -he -hemal decoeposi* ior. nrocucts c: r?FF, PVC-A (pvc r^:i; uh.nt, t--- * h a 1 a' plasticiser; "325. filler (CACC3): 2'.I", Fvc-C irve r esi.t:: '1W1' 5:11 -r: 2 5), pn 1 y f lucr ca 1 kc xv chesphe zp re, rcla ryic xypho sph a z o r. based or. t! * S.I.S.I. was found tc hs rTFF cjreatfr than 0 'rC ( A), PVC-C, gr-a sr than pclyfluoralkexyphcschazer.e greater than telva r y 1 o x y p 1; o s p- - hezre. Th er xogr a v in-e t r i c ar.d differential the racer? vir*.r ic aralysis wn-re made cn these two polyph.es phazar.-3 r=sins in a nitrogen atmosohrre at different heating rates. The pci vf lu o r ca 1 k.c x y phosphaz* ne rtf cor oc s - 1 with a single activation er.erny o* 3^,8 kcal/zcle leaving r.c residue , whereas the pclyalkoxyrhcsrhaze.ne exhibited t wc nrcce s se s with activation energies of 37.7 kca l/mc l-`- and 23.7 kcal/ircle re s o e c * i v s: y. The latter also left a substantial residue which can fc= asscciated with its improved behavior cvcr the f 1 ucr C-mate r ia 1. (AuM:e r) descriptors: ^Plastics, ^Thermal degradation, *Toxic hazards, Phcsrhazere, Sen se s (Fh ys ic 1c gy) , Irritation, .`ice, Folv Terr, Te cc mpos i*-. ion, Thermal stability, FI amabi li-y , "clvviry 1 c h 1 o r i d =-. 30 I-'! 2 h-h a I a t as , hitregen Plasticizers, Fillers, Th "tonr?- v i re* r ic a n a. 1 v ? i r , to Identifiers: *Pcly(arylcxvphosp)-3zerc) , * Pc 1 y (e 1 uc roa. lkoxyp h o s p h. a z e r =) , NT'SCCCXA o cKn) -u AC-AChg 778/7ST N'TIS Prices: FC AO?/rF ?C' f* *? a 1 *" h Hazard F v a 1ua *io n/?o xicit y r^r^rsira-icr : - co r *. 7 e - 2 - 7 3 2 , *rlc!' Plastic? ard r;ini!fcr.'irim Cciroany, C^lurtus, 'hio Naticnl (390 !('( f!T i!C p: D 31 6 V, a rp 7 f ? ' r" N'o ; Pori ter : 25n NT C5H 19 for Occupations! t , J. C . ; poj-pt r t f-J, *r, c7t;, P7-f TF-7S-2l,-732 a f at y J. = 9p, and FrC !i?i ;?.AI772r "111/ .-tstreci: Fxoosures cf anrlcyees tc ch.-D'ic.il aasnts a*1 a soldirg operation cf the Welch Plastic?; and .tar. u fact ur ing Company in Cclurtur, Chic, were ret found tc he *cxic under th= conditions observed ty the "a'-icral Institute for occupat icr.a 1 Safe*y and Health (NIOSH) hazard ^valuation o^rsorns!. Worker `'xposur^s re t-onzan", bis-cr.lorcr.ct hy 1 ith-ir, 2,6-ditrt-butyi-p-c:esol, carter, ror.cx icie, re r r al de hyti t , hydrogen chloride, hydrogen cyanide, carticulites, st. the l?.--*s, st yr 3.tc ar. 1 vir.vl chloride v=re Jer ?rn rf ,1 ty rsrscr.al j r.d a r^a air sa xpl i n.o. vrrkers experienced upper respiratory and irri'atior. associated with the use c r" a reercurd polwirvl chloride and a cr v ] cr. i t r i 1 e-fcu * a di e r. e-r cl ys* y r-r.c nat^riai. 71-.'- us-* of this xtter:3! has he ? n discontinued. te-rcr ipt or s : `Hazardous naterials, *Indu = *rial ledicira. Particles, Hydrogen cyanide, Tcxici*y, Criteria, lr. spec* icr. Standards, recount nd atior.s , Industrial hygiene, Industrial atmospheres, Ixposur?, ^so: ratcry systeir, Fy= (Aratoit'y) , F^sp: r atcry ir. fee* ions, Ferscr.r.s1, Pcr.zer.a, Cresols, Carter, aor.cxide, Fcrma ld = hyrij, Hydrogen chloride, rtthclatas. Styrene, vinyl chlctide Identifiers: Plastics industry, *Occuca * icr.a 1 Safety ard, Health Act of 1970, Coxic substance?, Co luirfc us (Chic \ , Air saoplir.o, Threshold lir.it values, taxiiruB permissf blr exnosure leval, F t h^r /ch lcrosi= *h vl, "ITIS FEWOSF "P-2PS 111/1SI FITS Prices: PC AOI/tF a<~i R&S 025416 1: l *. i 1) J' .-, 'l \ / <*^ h' --1r i. *, " 1 ', " , ,L i <^J . .J `"^ Toxicity of Plastic Ccmh us * icr. Products. ~cxicoloureal d "J cdolcqi =5 * c * r ^ s 5 ch^- !velativ-? q * va r d s c c T h _ r m 11 r a co * i1 o s 11 .' o r . r c d e c * s f.cc relvm^rie "at.trials Pitt sturch Univ., Pa. Graduate Fcnccl cf Puhli bureau or' Standards, Vias h int cr., :).C. (2t1j '3') Me a 1 h . *"! a * : c r. a 1 Pete:?! :?c*.. ''.'THcf; ;,iarie, Y,; Harrow, 2. P279uTU Fid: f-.'l , 51 \ , f PG = et 77 31 3p Grant: VBs-5-9rC9 ."'or. iter: MES-GCF-77 R c C. CFA I 77 In Abstract: Sensory and pulmonary irritation effects of thermal degradation products from natural arc syr. *h-*tic .ma r lal s were studied u s: n c irrce, tice were iist-f! rc develop a st-r.sony irritation s*r^ss index based cr cha me s ir. respiratory rat;. in add i-ict, acu*e Ie*halitv was ottair. ed. p qcc - re sne r curves w 0 r n oir. 'rated for d `:co n pc si ti cr predicts from rruolas Fir, F 7 c, flexible pc ! y ur * ha r , `rfion, and fiberclas reinforced uclvestet. similar data wer- obtained for cc, CC2, lew c 2, acrolein, KTl r.d c 12. preliminary studies on * t- = pulmonary e f f e c* s 0 f cembust icr. rrccucts usirq rabbits are also reported. Pescripters : Plas tics. Toxicity, Hazardous materials, Combustion pro due* s. Ir.h ala * i c n , C hlcr i re Hydrcqen chloride, Toxicole ay , "" hedelcqv , Tice, Labe:: story anim .s, 1 xp r i.T.c r.*a 1 data Ey rclysis Exposure, Tables (Cat a) , Polymers, lethal dcsaq~, Fioassay, ?abhi*s. Polyvinyl chloride. Polyurethane resins, Ttrafluorc-thylere resits, fiberalass reinforced plastics, Fclyes*er resins. Carter mcnexile. Carbon dioxide, Cxyqer , Acroleins, Louglas fir wood Iden*ifiers : Toxic substances. Animal models, M TSCC.T KPS PP-2F7 233/5ST MTS Frices: PC Alh/.-F Adi f =oistry of Toxic Effects of Chemical Substances. 1978 edition Tracer Jitec, Ire., Fockville, ri. * Nat ion al 5 f ::v an d H e a 11 h, pocbville, He. (L- ^ d 2 5) for occupst icr.e 1 Annual r F' * .r;r'CF: Christensen, Kerber*' E.: ET.icra $.; lewis, nich?.rd J. St :2fc?ui.' Fid: bl, 8J, 57 Y *, 579, Jun 7* USHf* Con* ract: CHEW- 2 K-7 5-CC 2u icnitcr: NlcF!'-7t:/ 19 1 Supers? '3 as P E-- 2^ f; 5 57. Fairchild, rcwi:d J.: C i r r c 11, n^r.*, uuo, 91* S- CFM77 1C. Abstract: The 197 6 aditicr. of hh^ Fegir.Ty `of Toxic Effects c: Chemical Su bstar.ces, fcrm^rlv referred *c as the Tcxic Substances List, is prepared annually by the National Institute for 0 ecu pa* ie r.a 1 5aie*y and Health (NIOSHI ir. ccirpliance with the Occupa ticr.a 1 Safety ar.i Health c+ cf 1970. T he 197* FFGIST'Y contains some d2,C8 listings cf chemical substances; 5, 228 mere *`har. thft 197 5 edition. Its purpose is tc provide basic i r.f or ma t i c r cn the known toxic and bicicqical effects of chemical substances for us= cf r itplcv^ts, en-Dloyees, physicians, industrial hygienists, toxicologists, researchers, and in nen=ral, all concerned wit!', safe hardline cf chemicals. The absence cf a substance from th* PiGITTFY does r.ct indicate ,:,that it is not toxic. Drugs or therapeu*ic chemicals ar -he FFGIFTFY have beer, included if they have been reported tc produce a r.cxicus affect. Descriptors : "Tox icoloov, *Cheirical ccxccunds, *8a?ardcus materials, Tr.d axes ( Document atior.) , Public health, ccsaq. Toxicity, .r.dustria. T hygiene, Standards, Chemical properties, Exposure, Asbestos, v'f pestjeidas, Carcinogens, Vinyl chloride. Aquatic bioloqv, s"gu1 at. or s v*i. Identifiers: *Tcxic substances, *Occuoa- icna 1 safety and heai*h, Maximum permissible exposure level, occupational Safety and Health Act cf 1 79 , ' NTISHEWCSH ? E- 2 * 8 29 5/ 5 ST NTS Prices: PC A99/."F AM rt". s-p1*. ^`r-yr'-v-, "'yf'S ,^??\ ' !!eal-h Hazard ?valua*ron/7oxicity a itnir. 'v r: 75-1 a f-3C*>r to!?: wll Errilirn Companies, -.'is'.rrr. ^ ^ :^Z ` ;; 0 ! f r ^a^icral Tr.s* . for Cecupa tior.a 1 Safe*'/ (39C 766) AUTH f F : Gills s, i, ; March, l. Z2C.d?2 fid: (2, 67, 571', e 7 Y, 9ur, Jul 76 If f = rpt ho: N'lOSH-7 3-75- 16 6- 10 9 v cniter: IS and Health, C i no i rn,a * i, fan, u c: CP V> 1 1 Chic. Abstract: Or. : l.= t a ?i i = cf medical ar.d a r vi rcn m -`n *e 1 da-a collected at * he v;at?r Well Crill^rs in vs fT.^rn jT,r>r p rclyv^rv^ chloride (PVC) csmfn*. is not found to cons*: tu*-? a h*a.i*h hazar: ur'? = r cxistinc condition? of u?c, Fr. v iron mot * a 1 samples show only lew levels of t eT e hydro fur an and r.c detectable levels cf cyclohexanone. ?'?ntr.3= tc medical aues'`ior.r.a ir = s indicate no symptom..- associa-ed *i*h exposure tc the chemicals. Crscript ors: "Polyvinyl chlcrid?, medicir.^, Veils, Trillinq, Ccm^.n*n, hyoier.a, Environmental surveys. Cycle hexarenes, 70x10010911 "Hazardous n a t e r: a Is , * 7 n d u stri a l industrial a t :n c 0 1; h - r - s , Industrial Sa eclino, Chlor oh ydrocazhens. Identifiers: "Toxic sutotances, Occupational 1c:'"tv and Health Act cf 1 9717 , NUSHEKCSH NCTS Prices: PC AC2/MF A01 ft 30 fio CO < o NJ CJ1 b 1 (O f>-ar ford Research Ins*.., Foundation, Vis h.: r.c* cr., D.c. mo eor'- ) F i a r K, ::a i i t. 'National science rch > z r 1 i*o ' ?. *** ^r. ^ I *' - * '*^ . < Final rdt. on ?h?ss 2 V~:! r~: 3:ct, 2. 1. ; Chan, F. V.; .!or,-s, . * . I. Flri ; 7?, FT, 9FH`, 6 f , non*, c 7 Y * .A pr 7 c 19 5 r* PrcT`.ct: SFI-FC'J - 3 IR* v,cri*cr: *- S F / F A / F - 1909 ,cea ?.Isc n?-2*3 191 ar.d PE-2* 3 163. l . : ;j, 2. p / T77 CH Y cC a 1 r h , Ahstrac*: Ir Phae* 11 of This *vc-rh?.s- = f; > r chemicals havir.u *v= c r ? a t e- s t rotor, tial for =nv; :oru- * a 1 " f e c r :r s t u d i 6. lr. f o r t, a t ion. vas collected, cn *hs ex' = r.' or the exposure of nfa - r v i * c r. it e r. t to ``less ch?T;calf idurirn mar. ufac* ure and ns| and or. * hp possible a r. viror. me n t a 1 "ffe-cts cf * his ;<rcsu:a (cherirai, physical, arc biological preperries, persistence, ar.d toxicity). Th-> c),,?r ic = 1 s rtudie.d i r. this volume a r a as follows: n^r-z^ra (chemical uses) , silicone fluids, Nitrct? rzrf , Tc 1 ue r. Dd i: sen van a to (TPl), Xyleres - mixad. total, Aniline, Pirtthyl tar e ph * h a 1 a* <=, Tr ich lera f luore.'.'ha r.e , p-rich ler c her.z en =, citHcbis ( her,7 o t b ia zcl* ) , c-ri o h 1 oro t.-r. zer. *, T-* ra bre moe t han = , to * h yl er. = { his ) -2-c h 1 o ro.ar.i 1 ir a, ? o ly ha 1 o ae r.a t ed hipher.yls (Arcclcr 12ih) , Tricresyl rhesrhate, F incr* sea r.t hriq.tt-nir.o aoer.ts (rc. 28) , Folyviryl chloride, yethyl-nfc chloride, Cichlcrcprcnere, Dichlcropropane mixture, -r.d F*h y 1 chloride. (Tcrtions of this document are r.ct fully legibl-.) Te sc r i p t cr s: ^Hazardous materials, '`Chemical industry, * in vi toner, t a 1 i.mpac*s, *Oraaric compounds, *a r.u r a c t u r i r.g , utilization, Chemical properties, rhysical properties, Toxicology, 3icacsay, Public h?al*h, 7 a blas (Eata) , Releasing, Air pollution, fat``-r pollution, Chemical analysis, Soil analysis, F*n7er. =, Sii:oon-s, " i tr c hf-tt; r, es , Xv ler.ns, 'r.ilir.e, Eipher.yl, Polyvinyl chloride, Ci lcrc*" th a z : s , FI ro resconce, C r* ica 1 hriahts r.e is , Industrial vast's, `-ilcc-r. or.uaric c c.m tour. ;:s Ider. * if iers : t-t har.'/tr ic hlore- lucre, 3 e r.zona/d ioh 1 o rc, E11.an.e/*e tr a- broni'-, Arcclcr 125U, Prcpar.-e/dich lo rc , r * h y 1 ? r e/c h lo r c, Tsocyar.ic acid /(ten hylpher.yl-tne-ester) , Tercr'h*hr.lic acil/(OiTe*hyl-est = r), Er.z ot h i azole thicls, A n i line/K-F-b is (Ch 1 crone th vi ) , Pho s ph at e/*r icr syl, FTTSSSFFA, f'TISSFI P P -- 2 ^ 2 16 2/rP7 ?:TT3 Prices; ?c A C q / " F :"1 37 fio (/) O cIVn) ofo p 'i r ic* 'j: -f: Ch ' t. i ca n "I'm, ').T. ! efosrrh .* r r - i Na-ior.al A UT!! 'l': Sr^wr, 0. L. : C!::r, ^ 'i. ; Jor-:s, J. '* . r . rl(-e>r:i Fid: *7 A, c", *=i h H * , if, ^ n yj * , c 7 y. 1 n f 'reject: S ?i-FC" - : vor.i *or : vsF/F A / I-H/ 1 9CA T = aisc F D - 2 ^ *1 1fi2. 1 : I i. 0. :7 ~ / T 7 7 C R F. : * cC a 1 h , 'Fs*.:fCt : Ir. rham II of -his -vr-phasi error*., d ^ ch a.ties Is iavir.o n^^5*ocf; rr*"r. `i ? 1 For o n v i r o n x a r. t a 1 effects v^r-. o - n d i 4 d. ffi'-ior. ;s r"U.ec*' 'd m * h. a sy-cr* o I the ; * rosu:? of 'hi1. 7 r. v i rc r. t c r A *r <-htrc chemical? iriurir.n ira n uf ac*. ur? ir./} us = | am or. *M pcssihie e rvircr r.- r tal =f fc:? cr thro exposure (chmica 1, physical, or d hiolooical prepar r is? , pc t r ist*-nca , arc aox:ci*y), a <tu *!?*. ior r. a: rs u r v n y cf industry vas conduct 8,1 * o de*orxrra * he axcur* mi *y;.cs cf Icfs-'f ir. * h c n am fact ur irg darts. I r f c : ~3 ti or. frer this survey i.= ahulated. Zha f c 1 lo wi r.-] = u:nr.ary reports ar = mhaft*ad tor =ach of th = 'r chemicals: (11 flow diacrax shming i rd us tri a 1 data or. * h = amounts used fer various ap pi; c at ic-n.r ; (2) A ore-paqe assessment cf * h-' data gathered cr. tcxicolccv and e mi rcram "al r=rsir rare -> ; (J) A ron'pnmr prir.tcut of a mhuler summary cf th'7, important data ca* f -'r >:-d: ar.,J (d) Ccpier cf the 25 most p e :A: r.r- n t abstracts four.! tr. 'he ara cf texicclcqy, "hr report is divided :n*o five volume-?; included ir this volume are chemicals 1-20. (Terriers c: this Iccnaen* arc r.ot fully 1ec1h1 . ) Cefcriptnrs: *Kaz3tdcus xar^rials, `Chemical industry, * in virorm er. tal g, ,irpacts, *Crgar.ic com pour, ir, ran o r a cr ur it nt 11 ina* i m Chemical nrop-rt ias, physical properties, Tcxicclcuv, Hioassav, dhlac h---alth, Air rcllutior, Ta hi71 c (Pa-a) , Felea.oir.c, vir.yl chicrid-', creeds, Ir hvl ferzer. J, Vir.yliden* chloride, Tolu-p.e, earner. * e t racr. 1 c r id e , -atar n^llu*1 ter., Soil ar.alvsis, Chi- sical analysis, 0 ic f lor edit lu crcxe t ha. r.c , T = * :?.n r h yl lead. Chlorine alichitic corpcundo, Industrial wasr = p, ? h r r. els, Halccen ccxrcunds I d e- r. t i; is r s: Uonar.als, Ear zooy r an es , B0 r.ze r.a/h`-' xa.ch. loro , Ithylme/tricKcrc, It har. =/* r ich 1 crc , nth yl = r. -`/chi oro , Fhosphoriux ohlcri!e/t'>traltis(!!ydrcxyx-=-thvl), Bu-adiTtc/^'-xachlorc, ? * h v 1 e r./ d i h r - oro, I - u y> ilar.e/dichlorc , P hes that a/`r is (T throic rro t y 11 , XTISdOFIA, 'C'sc:- pc-2Ai ldl/OSI NTH Pricm: ?c ;. ru/yp ;.r i 3J Q </> o ro cn NO Res ?arch Program on Hazard Priority Pinking o: .`la-tu f ac* ur an Chemicals - (Ch 3m icals ' 2 1-4C) `f{, Stanford Research Inst., Foundation, Washington, D.C, 3J2 50C). ' Renio Park, Cali:. *?Ja* ion a I Science Research Acplied to National d-reis. ( 33 (/> O IO <J1 IO ro Final rapt. on Phasa 2 3rowr., S. L, , Char., F. Y., donas, J. L. , Liu, D. ii, , /.cCal.-o, H. .". D ib 5 512 , ,' Fld: 7A, 6T, 6311*, 63 , 39E3, 57y c;raI77c3 Apr 75 19rp* Project: S 31 -RCFJ- J 3 3 b > y.,." .donitor: :o?/2A/E-1903 See also' P3-263 161 and PB- 263 1 63. ?' ! %* '{& -. Abstract: Ir. Phase II of this two-phase effort, 30 chemicals having 4j \. * s' greatest potantial for environmental effects were studied. 4 " Information was collected on the extent of the ;xpcsure of toe environment to these chemicals (during manufacture and use] -ar..i or. me possible environmental afreets of this exposure (cher.icil, pr.ysical, and biological properties, persistence, and tcxicityj. Che chemicals studied in this volume are as follows: Benzene (chemical uses). Silicone fluids, Nitrobenzene, Tolucnednsocyar.ate [-01) , Xvl er.es - mixed total. Aniline, Dimethyl terephthalate, 7r icn icro: iuor ox = tnir. e, p-Dichlorobenzene, Dithiobis (bar.zoth lazoia ) , o-ricr.lcroner.ze: a , Ten rabromoet hane, .dethyler.e (bis) - 2-chloroar.i line , ?ciyna logena:eb- biphenyls (Aroclor 1254), Cricresyl phosphatt Fluor? see r. t o r 1 c r, t = r. 1 r. y agents *(r.o. 23), Polyvinyl chlond. he: hylme chlor id =, Dichloroprope.ne, Dichloropropar.e mixture a r.d ethyl c.t* ond -. e. ) r.dustrv, *c.n vi ror. aia.tt al Utilization , Chemical loassav, pun lie heal', r., Tables (Data) , Releasing, Air pollution, Water pollution, Chemical analysis. Soil analysis, Benzene, Silicones, i tro her.zer.es, Xylenes, Aniline, 3iphenyi, Polyvinyl chloride, Chioroethar.es, Fluor-3sc3r.ee, Optical bri jhteners, Industrial wastes, Halogen organic compeer. :s Identifiers: dathane/trichiorc-fluoro, 3er.ze.ee/dichlorc, thar.=/t r.r a- oromo, Aroclor 1254, Pro pane/dichlorc , Cathy ier.e/cr.lcro , loocyanic acid/ (Cethylphenylene-ester), Terephthalic acid/ (Dimethyl-aster) , 3enzothiazole thiols, Anilir.e/tl-N-bis (Chioromethy 1) , Phosnna t e/tner e- syl, NTISMSFRA, NTISSRI P3-26J 162/OST N'TIS Prices: PC A09/CF AC 1 lie? * w." `.--'cr:-..ViVilw' ,:v*. ,.v . II h- - - f< * y;.', .pi a"" .umii iLi?pwMPi I lit * T' ...-, v rf , . ' ; y.'U ' hs-it - ea rch * Program on Hazard Ranking c: ' a r. u ; ct w r a- " - - a - * SfJheaiCilj 1-20) y ?k!L y, v^fJtanford Research Or.3*.. , Menlo Pars, ; ;i at tom 1 V * . w ' i ^-Foundation, Washington, D.c. Research Anplied to Rational N'-ais. ( : 312 500) Final rapt, on Phase 2 2 _ o w n , 3 *. , i.han, r . * , Jo ns s. D 1 6 5511 rid: 7A, 67, 63H*, o 6, Apr 75 196 p* Project: SP.I-EC'J-3 366 Monitor: N3F/3A/E-75/1 90;. See also P3-263 162. ... - * . u, 993-, 57 V j. * , ..c. GBAI77Cd 3D CO ro cn Abstract: In Phase II of this two-phase effort. ch eaicals :i a v r r. f7 NJ CO the yreatesi potential for en vrror.nental effects Information was collected on the extent of t:e oxxppoossuurrct or tho environment to these chemicals (during nanuracture ano u se) and or. * possible enviror.aer.tal effects of this exposure (cheat cal, on y o i c. and biological properties, persistence, and toxicity). A q U % 3 t Z. o nr. d: r - survey of industry was conducted to determine the a sour, * r. a " 7 o: losses in the manufacturing plants. Information from 1 ni5 oil : v v l s -.tabulated. The following summary reports are submitted f or rach OZ ` ri 33 chemicals: (1) A flow diagram showing mdusr.n ^ - a O4* i amounts used for various applications; (2) A one-pays assessment the data gathered on toxicology and environmental persistence; (J) computer printout of a tubular summary of the important !ii*6 'J a i; and (4) Copies of the 25 most pertinent abstracts found te j.rsec oA r4? toxicology. The report is divided into five volumes; eluted : IS volume are chemicals 1-20. (Portions of this document are nc 1 ll: legible.) Descriptors: 'Hazardous materials, "Chemical industry, * Environment al impacts,','; "Organic compounds, Manufacturing, Utilization, Cnamcui 'properties. Physical properties. Toxicology, Bioassay, public haalru, Air, pollution. Tables (Data) , Releasing, vinyl chloride, Crescls, T.t.nyl .benzene',. Vinylidene chloride. Toluene, Carbon ter. rachicr me, Water pollution, Soil analysis, Chemical analysis, Dichlor odi f Luo r or e t.uar. e , Tetraethyl lead. Chlorine aliphatic compounds, industrial wastes. Phenols, Halogen compounds Identifiers: Nor.ar.ais, Benzopyrenes, Berzene/hexachlor c, Ethylene/trichloro, Et har.e/tzichloro, Eth y lene/ch io ro , Pnospi.onium :chlozide/tetzakis (Hydroxymethyl) , Butadi er.a/hoxac hlozo, Ethy Lena/!mr- omo, Sthylene/dichloro, "TISSUE Phosonate/tris (Dibrcnocror.vl) , '.'7 13 "3 FI A, am ffrcV;. ;;. c m . K..! -hl'i, -}' */ ?1 ' A - P^Toxicoloyy of *!. plastics Having Cor.:act with Dlood, 3-?:>cr* #K<; v mr my ^.'.Traveaol'- Labs., I nc., ,io:*.on ^31ood last., 3ethesda, Kd. , ,' ' ' <>,< -. ^ , ' .jJtAr.n ual rapt. V1 Josephsor., A, *1. 'D1503C4 - rid: 6T, 6L, 57Y, 95C Grova, 111.`Nat iota i CHAI77D7 heart, , Lung, mu V .'lav 75 :' 22? Contract :,, NO 1-US-2-2990, ?HS-72-2990 ; Monitor: NIH-NO1-HB-2-2590 |l'. " ,, ,-i ^..rtbs tract Di-2-ethylhexyl phthaiate (DEM?) was extracted free polyvinyl'" chloride (?VC) . This material was diluted ir. startle rat plasma ' and used to inject, IV, groups or rats with a 3.7 ^,!iiy/Ag/ir.jection, which is equivalent to the DEHP dose that a patient '.ffliwouldV.^receive from' a total exchange transfusion of blood. Growth .vyrates, '.Tigress reactions following injections, hematolojy ar.c serum chemistry,, parameters, gross organ pathology, absolute and relative A ' organ weights, histopathol egy, and residual DEH? levels m plasma and tissues were similar for all groups, including plasma cor.-rol groups. , . No toxicology significant changes were observed. A:''. ^AV,'' vrM : iste ,,:V.Descriptors: `Toxicology, `Plasticizers, `Polyvinyl cnioride, Toxicity ? la sties, Medical supplies, Medical equipment, blood, bio-assay, Eats ^V,:-Laboratory animals ,, TmUdentifitrs; `Phthalic ac id/bis (Ethylhexyl-estar) , fs^materials, ..diomaterials, NTISNIHULI 'if-';"'1 -v -;,,; ` ' *>:P3-262,7260/3ST , '%:** . at. -g; > N'TIS Prices: ?C A02/Mr A01 *3lsod compatible >< V > 1 # R&S 025424 vzr>\ [w.`V 3t"\f s lp>> Sir-.*, . dj.C ' v . , t'JVWt. "m B >;',r w-V/ r'\jX Bii `) rn&MM% "V-* f m mm* Special Listing or Current Cancer Besearch on Carc^^ ^r.ic j La Food and Drugs (Alor.y with Related Epidemiology) .: -.si f 5ait:ssor.ia[i Science Ir. tor ma tior. Exchange, Ir.c., * ah i r. ;*.c:., ~,f. Cj Cancer Jesaarch project Anaiyais Cer. te r . * :.'u t ;cr; a1 Ciro-i1 ~nst., 3etnesda, .Id, International Cancer Research Da~e Ian-:. wl'492rl Fii: i'.:;, 60, 6S, 08H* , 57/*, S7Z, ob u * 2u :;cv 7 6 2bp* 7 '' 7 7.17 Monitor: :iCI/ICKDB/SL-76/25 See a Iso ?B-2 61 0 70. nbitract; ;Contents: Arlatoxir.s and other organic naturally occurrna carcinogens; Oncogenic food additives, residues, ar.i environment el contaminants; Epidemiology cf cancer m relation to di-jt; Influence cc dietary factors on susceptibility to chemical" carcinogens' in axperiraental animals; oncogenic side-effects of drugs. Descriptors: `Malignant neoplasms, 'Carcinogens, "Feeds, (, ; atiology, Diet, Food additives. Pollution, Zr.vircr.r.er.ts, titroso- i compounds, Aair.es, vir.yl chloride, Esoohaaeal carcinomas, 3~-ast5 ^ neoplasms, Chemical compounds. Tolerances (Physiology) . Zoi ' <- lo - , r : Antir.eoplastic agents, seserpine * ' ` 'r . Identifiers: Aflatoxins, .My cotox ms, aiotoxir.s, Mr.rosca.v -s, c-c = -' I , environmental health, .vtiSNIHKCI "j PB-261 671/257 NTI3 Prices: PC A03/MF A01 ^ 30 flo CO o fo gttal cfon I4 R&S 025426 ms j? .*.' '* > yi'kr c.. is:. Occupations1 V i.'.yl Oh Lor iie Int oxsixatsii . n i Is h lor :,ioj] ; nr ox ica r ion i ;: r. ro; ~nviror.aenr.il ?rot action Agency, .-sseircr. Translation .Services Section. Ant on yuz her. ko, '/. a. D13U502 ?l i: b.I, SI d7 7Co 1768 Sp ."lap*. No: E P A - ? 3 - 7 6 - 1 n 5 Monitor: 1) Trans. or digier.a Truda i Pro f ess icr.-. 1 ny e Euno 1 e v : r.i /a n 50-5 2 Plod. ('! V 1 .. Abstract: Cases on" acute vinyl cnlonu- into xicat icr. ir. a: extremely rire and are usually lue to massive exoosur.- to t suostance during work in closed areas and during acciier.ts. Jr.t, indicated conditions even short-term breathing ct vinyl union.:- ' cause sudden loss of consciousness and a state c: narcosis. In n.-.o. cases when the patient is not immediately removed rri" nr.- gas-fil. room, a coma may develop that is lethal as the result c: resrirato: arrest. With timely rendering of nrst aid, patients seen -r.^-r;1 in the comatose condition, nut consciousness may retain mu !e i :cr short time. Over the next few days, neadacne, di r.i i r.'ss, :er. er weakness and an ir.c'lir. a ti cr. to rradyeardia and ir'-risi r.ypct;r.y :: observed. The patiant practically recovers in 5-7 lays. Descriptors: Vinyl chloride, `Industrial h y ; i -7- , Hazardous materials, `Toxic diseases, Chemical Translations, Chlorine organic com pounds. Industrial atmospheres, USSR, Respiration, Oases, Toxioo, * :o*i:i-. trrjors. nedicm ; Identifiers: Occupational safety and health, effects (Humans) , Toxic substances, r.TISEPAISD ? 3-26 1 76J-7/ST NT 15 Prices: PC AC2/:'F A01 *; no,, i at i or. a to oro cn r-foe vl I6 R&S 025428 Current Awareness Service for Toxic Sul Henort Number 2. Part 1Z .ces (C .-.T") 'J IT* *1 , little (Arthur D,), Z r.c. , Cambridge, ."aGs.^r.vin;::,. t jC ti o:. Agency, Washington, D.C. Office of Toxic Suostances. (;i' abo Annual rapt 3124132 Fli: 133, 67, od`, 57 T* OHA I 770 5 "0V 7O 36 U p* H apt :io: ADL-C-77355-Pt-2 Con trict 2PA-68-C1-2694 tonitor: E?A/560/7-76/0G2a Sea also report dated Dec 75, P3-250 C 75 and Part 1, P3-2n9 .ioC Abstract: The scanning topics included ir. this two part senes are the chemicals and subject areas as follows: Acetonitrile, aery lor. itril- arsenic, aryl phosphates (phenyl, cresyl, mixed rhenyl-c resyl; asbestos, benzidine, and salts (hydrochloride, sulfate), 'nor o: nreminated oipher.yls, dichlcrobenzidine, dicxane, ethylsr.-iiai:.* f ?'. m - retardants, fluorocarbons, haloethers, hexachicrcn e n z e r. hexachlorobutadiene, hydrazine, derivatives, ar.d salts (syn at : i r. s yn dimethyl, monomethy 1) , isocyanates (organic), liiuefacti or. a r.c jasification of coal, met ny 1 er.ebis (ciiloroanilir.fi) , modal eco s y s t e ms (environmental fate testing, microecosysteas) , naphthyia.nir.es (alp r. a, beta, N-phenyl derivatives) , nitrilotnacetic acid, o pt ic al brighteners (fluorescent whitening oerchloroethylene, pnthalates agents, (dioctyl, fluorescent iyes ) , di-2-otr.yl :: s x v 1. ) . polyurethanes, propiolactone, trichloroethylene, sr.ale oil ext and refining, vinyl chloride, vinylidene chloride, ethylene dib r oaiie, and nitrosamines. Descriptors: Toxicity, "Chemical elements, `Pollution, Vir.yli u a .t = chloride resins, Acetonitrile, Acrylonitriles, Arsenic, Phospha t z s, Cresols, Phenols, Asbestos, Nitrosamines, Lactor.es, Re.uztdir.e, Ho ror., 3iphenyl, ' Dioxanes, Aziridines, Fire resistant maten ai s, Fluorohydrocarbons, Ethers, Haloger.organic confounds, Coa: gasification. Hydrazines, Isocyanates, Ecosystems, Amines, Opt ica: brighteners, Phthalatss, Polyurathane resins, Naphthalenes, Shale oil, Extraction, Refining, vinyl chloride Identifiers: Diphenyl/bromo, 3enzidine/dichloro, Coal Iiguefact ibr , Henzene/hexacnloro, 3utadier.e/hexachloro, A.nilir. e/N-N-cis (Ch loro me th y- 1), Naphthyiamines, Acetric acid/nitrilo-tri, Fthyleno/cnl or o, Eth y ier.e/trichloro, 5thy len e/libromo , NTISSPAOTS P3-260 361/13T NTIS Prices: PC A16/.".P A01 r7 -*,v-- ssfKssssS Igjp: vir jffi''1' ^ l'; 7r V -:!y <*! m :or Toxic Substances (CATS) .`ir/Jli-.: /, Cambriaoe, .lass. *er.vircn'meutal Protection p&l-`V--. Agency,' Washington, ' D. C. Of i ce of Toxic 8ubsta ness. (208 d PC ) ."Sniial rest, A. '`.v\$. rS'o:^ T , , . 0124 131 :i'v Kid: 133, 61/768 , 57 Y> GP.AI77G5 ' 1 :lov 76 ' *u07o -j'.`: : a<?^* u ^vv'1 T'v :`-:i'V: 3C_6_op_n.Ltralicot: AD1.-C-77355-Pt- 1 SPA-66-G1-269U V ilon itor: 2PA/56C/7-76/002 - ...See.also -Parti#, ,!?D-260 361 . v -$' -.v. .-a :> " ' ' SM:'Vv'i.4;- . -^i/J.'Abstract This;4'cumulativ e ; report contains-' 26 current awareness TC'-i'1 .-;iv ^documents -.rpre pared.; bi weekl y from '25 August 1 975 through- 9 August :i97d, '/n^du ring':-;-the4- second.; year ; , cf a t:iwo year project. Th^ purpose.of this S '.W-h'1 1$Zr. A \- Z.iV.-.i.llI.i.VpEronyjeir ocrt. m... `awnats.a.'-i.,,;,;;t_"'_o.P._.ri-oprt_er_oc_v_t_ii.o_d_ne_ tA..h.g'.e.encO0yf;f,ifiwceith of Toxic Substances information on (OTS) , !J. S. r.ew 1 uses .,oi .v./ .'-'`exi'sting.iich jmical products and with information cf obvious potential environmental concern for both new and existing chemical products. Tor * ' , ' -`it;' eacir^biweekly . document a core list of approximately 80 journals -was scanned.: for .information of interest to OTS on mere than JO touics (compounds,. classes of compound; id subject areas, e.y., model ecosystems)"". Abstracts were prepared for all items selected ar.d th^se- abstracts .ware presented biweekly under the assign5 topics. lr. a d,d i ti'o n,v 4`a "'General' Information' section was added to accommodate ibstracts lit or topics -, not include-: in the original. list of scanr.ir.' - tifpl'Opicsiiyvfaiweekly " subject "indexes were cumulated ror this annual 4'compilation, and an author index was added. As:' resistant materials, Flucrohydrccarbons, Ethers, compounds. Coal gasification, Hydrazines, Isocyanates, ` " Optical, brighter.ers, phthalates, Pol yuretnir.e my ft'--.TM , , i) a'pht h y la mi nes, "Acetric acid/nitrilo-tr: ' - 2th:ylene/trichicro', ' . 'fv : E. thylene/Jibromo, h'TISEFAOTS p fe'.A'l- '../v-r 60 <i3.6073STl;; ,,hTIS ?rices:.-..PC A18/MF A01 k^ri'r ;V; :> ' - Tt h yle r. e/chlor t fcV-'fta'Vt- * 1 1 v : -e ' Ml fe' I', *,i.- d';-, v ... 77 0|!,'-5-`5,A,,- s7Mf;-v- , /v -iv-.V.',/ m 1s IM' ffl:, 1^7 f.-'*7yS- v3pVufef . SJj-d.fjtj mm: itf it V"-: i'*.j ' ', ift - %fet, 0m::rare-i;. V*- ' The So-Called vinyl V i r. y 1 c h I o'r i d r K r a n x n e i t) chloride Distdsfi (Ufcnar j : fs r. a r. r. t e Environmental',, 7-protection Agency, it esearc.n Translation., services Section. Sue he, 3., Langs, C, -S. , Stein, G. , Veirnar., G. DC 14531 FI i: '6J, 6T, 57-V, 57V, odd CFA17702 197 5 15p Sept .`Jo: tPA-TR-75-6 Monitor:;13; Trans. of' Deutsche Meui2inische Wocnenschri rt p20 34-2037 n.d. . (West German , v >:! Abstract: . Since the first reports on impairments of health cf vcr.<=rs ir., the vinyl chloride (VC) industry appeared m 195d, and of wQr'.ers ;in the- .polyvinyl ,'chlorid? (?VC) industry m 19e3, attention has been } repeatedly directed at this branch of the chemical industry by further reports.syndrome . .vas observed which was si nil a r m its cm?, and bone ' changes to scleroderma, while its etiology u.-.: pathogenesis remained unresolved. Its principal symptom was the Raynaud syndrom? r=Kr.;;'3f igftV.' -":S*rvvf .' S'!,-;"'. b-'iJV important- features are summarized. , Descriptors:,., `Occupational diseases, *Vi.tyI chloride, 1 medicine Integumentary diseases, `Toxicol cgy , Dermatol ogy, dheoica. industry h.y "Skin diseases, Signs and symptoms. Gases, Pathology ^sfP* arth.hoopphhyyssiioolloogy,, Histology, West Germany, Translations . 'Mk.i \v- , 'hi. Identifiers:,' Air pollution effects (Humans) , Ir. vir cr.3*rt al . e a 11 h, b'.^fcoccuDational safety and health, NTISZPAISD ' : PH-258 ^38-T/ST ` NTIS Pri' ces: "PC" A'02/MF A01 El>,\f:/V- *:':, ;v y--v,v ' lw~, Ziyi. - g*vtvar,;.v;. -- '' { V1 SJ3^" ' "v= , y ,^ I-*'" . I'**' " 0 V.'tt* ft ;-`f 'it*' ;r ,, * ' IWcifi' ;V.: V , . v" I9 R&S 025430 ^.;7 F*yr < rtf p`/% T - an Ip^r 'H LfV'c1'1 : j|'\|F >,. if, *VS Vr % ;* . *: te: liWilV V !g ''v'F , ^ ' ,, standard uuuort and z.t viro.t mer.tu 1 iwcr Promi! gj z>i J -aiasior. Standard for Vinyl Chi oil i- Tnvironaer.til Protf.ctior, Agency, of Air.Quality Planning and Star, darns. DOJuuU fid: 1 3B, 6 J, 67, 7A, n Ji: , ntj , 3 -2 p 7 o 1 3 5 p kept "o: 3?rt/-o,'/2'7cj/00`Jb hon itor: IS See also P3-2U9 703 . Trier.-; ! ne A , ',7' J, :.: /;u.: ADJtrjct: A national amission standard tor vinyl onion.; ithyier.e Bichloride-vin yl chlcrue and polyvinyl cnori being promulgated under the authority or section 1 ior Air Act. Vinyl chloride has beer. implicate.: as the ;a:.;il agent or -angiosarcoma and other serious disorders, noth' rirctno uer.n ana noncarcir.oger.ic, in people with occupational exposure an*, ir. ar.i~ms with ' experimental exposure to vinyl cslan :, T-usonui- extrapolations iron these findings cause concern t.nat vinyl colon :a may causa or contribute to the same or similar iucners at gru-;.t ambient air levels. The purpose of the standard is to mime vir. 1 chloride emissions from all known process and runttve v-mio.. sources in ethylene dichl cride-vir. yl chloride ar.n tol/vi:.yl cnl in :e plants to the level attainable with best available control technology. Tnis wouli have the effect of furthering the pro -1 or. of p ;n. ic health by minimizing the health risks to the people living in the . vicir.ity of these plants and to any additional peepi- vhc are expos i>; as a result of new construction. This is estimated to hav-s tn<= affect of reducing emissions from a typical ethyle.t- junioride-vir, yl chloride plant by approximately 9u percent ar.-\ trot a typical polyvinyl chloride plant ny approximately 9b perce:.*. Thin uacur, e r. t contains a summary of the public comments or. the propose: stanutr: to: ZPA*s responses tc the comments. It also contains updated information concerning the environmental and inflationary impacts of t.-.e standard. Descriptors: 'Air pollution control, 'environmental impact stet-r * r.t s , Vinyl chloride, 'Hazardous materials. Chemical plants, Cos* ar.alysis, Economics, Public health, Industrial wastes. Combustion uou'icts, 1. en ? orceaent, Standards, Industrial hygiene, Particle, v-.s t- water, Water pollution. Pesticides, Aerosols, Testing, Toxicity Identifiers: Fugitive emissions. Air guality, :: 713 T ? A Axv P3- 253 827/53T .h'TIS Prices: PC A0 7/.1? AC 1 R&S 025431 :-ic` IT' g-V# Evaluation California Vir.yJ Chloride i a 13 s i o r. s i n _on 3 a act Area, C C/3 o NJ Ui fe U N> National C769UA3 /.ay 7j ."apt Mo: Monitor: Field Ir.vasti jettons Car.t=r, Denver, FI 1: 1J3, 66A, 6oD U7p fi3A:762`S EPA/3J0/2-7U/CC2 Id Colo. Abstract: A survey of vinyl chloride mis.aions :ro: tie American Chemical Corporation and 2. F. Goodrich Cheaical Ccopm/ snowed tr.it vinyl chloride monomer was leaving the plants via va-ar, sluayi, end air as well as in the final product, polyvinyl chloride. It is estimated that aoout 2.3 ky (5 lb)/day of PVC leave tnc- 3.?'. Goo drier plant, and 10 ky (22 lb) /day leave the American Chemica- plant m ire wastewater effluents. Smaller quantities were found ir. the sludge. The ra[.ort presents a plant evaluation and a sampling program. Descriptors: 'Pollution, 'Vinyl chloride, 'Polyvinyl chloni i, Surveys , Water pollution, Sludge, Air pollution, In fra res spe otroneiers, Evaluation, Industrial plants. Toxicity, Environmental impacts, Safety , Public health. Assessments, Sampling, California Identifiers: Long 3each(California), NTISEPAO P13-257 6U2/9ST MTIS Prices: PCS 4. C 0/M ? 5 3 . CO A*>v* 2I f!r. W%|i/:; i' ms?*,. g$$|k4" W; . 1 -.>'f '#; . ''''' .. * '*}' ` %' ' '"-1 .; Toxicity or the Pyrolysis products of 3p;-.ccra f t Materials Sv; Tennessee 'Jr.iv., Memphis. , , #:v . ' Annual-Report, ,:1 'Aug. . 1974 - 31 Jan. U7.6. Lawrence , w. h,' C 6 9 15 C 3 JTAP.14 1 j 29 Mar 76 79 Pent No: IJASA-C?.- 147563 Contract: NA59-13617 Monitor: 18' ...SV:.:": *,, 1. h > Abstract: Data is pre temperature necessary initiate thermodegradation or the polymeric . materials5 tested, (2) the relative toxicity of t her cod agr-idatior. products from the. var ious materials, (3) tr.i relative inportar.ee , of carbon; monoxide as :the primary cause or death (as contrasted" to cyanide or other'toxic gases), and (4) wn&ther or not the . haza rcis'.o: the .f'jyfuaes are; confined to the time of exposure, 1 or :-vh ether post-exposure death is likely. Two different experimental methods were employed. (Author) Descriptors: ., *Combust ion products, "Pyrolysis, "Spacecrift construction ;materials, "Toxicology, Carbon monoxide. Car boxy h eraoglobin. Nylon (Trademark) , Polyiaides, Polyvinyl chloride, Pats, -VTh erraogra vine try, Urethanes Identifiers: NTIS.VASA 117 6 -22b87/3ST, NTI3 Prices: PCS 5. 0 0/n?S2.2 5 R&S 025433 :4v. I P-4?.; f 'H> .;l; : II _ni 22 . yv; --.... . diti <f,*?i- XV'-' H: 31" -i- i; -VifS ?:a^l rept. 1 `lov-JI Dec 75 coing, John S. C'id 20 L2 Fid: 06?, 06F, 13B, 57V, 57H, 63A, Apr 76 30? 2071 tract : SPA-5B-01-2646 honitor: EPA/56C/6-76/002 See also ;report dared Sep 75, PB-246 213. 64G, 9? A S = AI7f,1h jV! ` Abstract:'' A sampling and analysis program was conducted to determine whether -and to what extent vinyl chloride was present ir. ambier,t"'air lua to/7, the presence of polyvinyl chloride products. Sampling environments were choser. tc represent real life, bur .to:: work situations where a significant exposure to polyvinyl chloride products mi;nt occur. A sampling and analysis protocol was developed with a recovery' efficiency of greater than 90% and a detection limit of K ppb (v/v). The two general categories of environments sampled warvehicles and commercial products. The interior ambi-nt air vis sampled from new and used domestic autcmobiies, foreign automobiles a.tc domestic ' mobile homes. No evidence of vinyl chloride was found. Tna following commercial vinyl products, when sampled i:. their normal environment, did not produce a measurabia quantity c: vinyl chloride in the . ^ambient air: vinyl wall covering; vinyl swimming pool liners: ar. 1 vinyl nursery products. A room being pain tec with a heavily pigmented red paint, was found to contain a very low level of vinyl chloride'."; Descriptors: ^Toxicology, Carcinogens, *.vinyl chloride, a , 'Automotive industry , Sampling, Exhaust emissions, products, Public health, Vehicles, Paints, Fabrics, Gas cn , Cas analysis. Charcoal, Adsorbants, Sites, Sources i- Identifiers: *Air pollution sampling. Cancer, Environme Secondary sources, .V.TISSPAOTS r poliution Combustion omatography - til hea Pd-252 966/7ST HTIS Prices: PCSU,00/1F52.25 v. 9; A* Ii 'V'...., iy ^ y.v 4` -* *,rH- - V...' , '^ Toxicity of '"Components of. Plastic Havir.g Contact with ilcoi !" . . , , Travenol labs., . Ir.c,, Norton Grove, 111. 'National deart Instil iiethesda, Ed. Div. of Blood Diseases and Resources. 4i X#;. Final technical progress rept. Jut 72-xar 75 xiripol. J. ?S., Garvin, p. J. , stern, I. .1. , Wallin, ?.. ? 0 fa 5 7 J C 3 Fid: 06 T, ' G6L, S7Y, 9 5C, 35A G 7 A17 M J Sap 75 340p,4 Con tract: " 0.1 - H 3- 2 2 9 9 0 . , Bor. it or: KIK-SO 1-H3-22990;! ana . -it; ' "'V Abstract: 'Method of dsoiubi ii2ation, dosage form at administration' are factors which are critical ir. tne distribution arc excretion ,of ydi-(2-ethylhexy1) phthalate (DEBP), one of the most widely used;- components employed in the formulation of riexioie polyvinyl t'chloride (PVC) . Changes in the apparent volume of -iistribuViphV.'>of > DEHP observed when aiueous suspensions w-re uset for infection o'fG^thV plasticizer indicated that differences in *. ne systemic disposition and distribution of DEiip were ueper.der.t or. tue physical state of the" dosage form. Valid studies or tne biological effects of parenterally administered DEB? must be performed with -a dosage form- , of 'the plasticizer which is lixe that -ccour. ter>-h it clinical situations. Whole body autoradiographic studies ps r for oed or. mice infused with serum containing 14C-D2HP showed rapid accumulation of ' labeled `carbon in the kidney and liver with rapid excretion into urine, bile,, and intestine. Essentially all the labeled compound -as excreted within 2h hours. Bats incused twice weekly rcr oC nays with raf,-,; plasnaN'jVv containing DEi!P extracted from PVC exhibited to *-.oxico logically significant changes when compared to controls. Tissue residue studies dir. man revealed no relationship between transfusion history and^'it issue content of DEHP. Copyright National Technical Infor,mat ioniser vice 1976.^ i '' . ' | ' ' s'` , < Descriptors: t, 'Plastics , 'Toxicology, 'Polyvinyl chlorine, Blood, Phthalates, 'Medical supplies. Plasticizers, Toxicity, Toxic tolrratcvs , v Dosage,-: Bioassay, Rats, nice, Laboratory animals. Absorption (Biology), Excretion Identifiers:4' 'Blood compatible materials, acid/bis(ethylhexyl-ester), NTISfilHHLI 4 rM`, ` Biomateria Is, P3-251 742/33T NTIS Prices: PC 10. C O/.XF 2. 25 ''nihilic y r' h 9 R&S 025435 R&S 025436 ?/S: 3* . X: nal Toxicolog, y,, of Plastic i Devices Having Contact with blood Utah Univ., Salt Lake City. Dept. of Applied Sciences. *Nat ional Heart and Lung Inst., Sethesria, 'Id, Pnar maceut real Pinal rest. 24 Aug 72-2J Aug 75 Petersen, -Pobert V., Lyman, Donald J., Soil, David A. C6232K3 Fid: 06T, 06L, 57Y, 95A, S) 5C G R A17 6 10 23 Aug 75" 248p Contract: PHS-73-29CS Monitor: NIH/MHL:-72-6-r Sea also report dated 1 Hay 75, P3-244 753. 3. IwinyiTw/ Abstract: - The.- project was primarily concerned wit;, toxicological evaluation of polyvinyl chloride and, ooze specifically, the commonly used plasticizer, di (2-ethylhexyl) phthalate (DEHP) . Evaluations are primarily concerned with long range, subtle toxici-y potential, although many basic acute and subacute studies were also conducted. The project is divided into twelve tasxs including an organizational phase, plastic composition studies, acute toxicity stuiies, tissue culture studies, subacute toxicity studies, metabolite identification, teratogenic studias, neurologic studies, larger animal stunes, analyses of human blood exposed to plastics :uring hospital procedures, and possible statistical analysis of human ?atie::*s .following extensive exposure of blood to plastics. ,n ' " f1 ` ..Descriptors:/ *Polyvinyi chloride, -Plastics, Plasticizers, '.*? axi colcgy, Patients, Tissue culture, Sicassay, Laboratory animals. Pathology, Rats, Heart, Phthalates, Dody fluids, uroir/gy, .'`.ice, ;Reproduction (Biology), Medical supplies, Mechanical organs. Humans, ...Blood :& J, ' \'` <?'/1 /Identifiers: fp.*31ood compatible materials, Dioma tenals, ` acii/bis (ethylhexyl-ester) , Metabolites, .vriS.VIHHLI Phthalic P3-250 -102/1 ST"; MTTS Prices: ?C38.GO/MF32.25 Ai #; 25 t, *\ W:':, 5>k-\ J . ' ` k&i'i cmi sst cn c v r. y i> .. _ tC'.av..*...'? t^ . - - c.. etnylene ^dicnlcriie-yinyl chlonie and polyvinyl chisn's plants is being proposed under1'- the authority of section 112 of th:- Clear. .Mr Act. Vinyl chloride -has been implicated as tne causal s;=r.t of >r.giosarcoma ar.d other serious disorders, both c ar cime : er.is end .toncarcir.oj2r.ic, in people with occupational ; xpcsurn a wit a experimental exposure to vinyl chio ride. reasonable extrapolations rroe ; these findings cause concern tnat vir.yl chloride aav cause V or' contribute to the sa.te or similar cisc:: =:j at present amoient ,,air levels. ' The purpose of the propcs-c standard is to minimize vinyl chloride emissions from ail known process nr. : rugitive emission r.- sources "in >?thvl sne dies lor id e-vi r. yl chlorine and polyvinyl chi oride `pylants to the level attainable with nest available control t ec n.noiog y.; This would nave tae effect of rurtnenr.: tie protection of public health oy minimizing tnc health nsxs to tne people living in the vicinity of these `plants and to any -jdiitional p-.-opi;- wr.o are exposed as a result of r.sw construction. This is astirat-! to hav a t a a .effect of 're-iucing emissions from a typical ethylene tic.tier ice-vm yi ;`chl or ids-, 'plant by approximately 9- percent and from a typical ' poollyyvviinnyyll..s.esnchioloriiddee plant by approximately 95 percent, environmental nlmoact and1.,.In flaatti:er. Impact Statements quantifying th^ impacts of tr.e 1 'r`.:p ro posed'i; standard and alternative control levels ar-- inclu:ed m tne f;doc ument 'A' ^Descriptors: "Ai pollution control, "Hazardous materials, "Vinyl -`chloride fif-> Ir.vir onaentai' impact statements, Cos a .. a j. / a _ r, health, , '' ''"..Combustion products, Law , enforcement Polymerization, Industrial hygiene, Particles, Fii'ers, .r.cinerator s. Aoscroer3(hateriaIs),' Waste wattr, water pollution, 'treatment,' Noise . reduction, Thermal pollution Chemical industry Ccobusti cm products, Mission ; . : e r. 11: i e r 3: f NT 131?AO?.3 quality, Fabric filters, Figi-ive amisjionr. : ? 3-2*0 7G3/03T NTI3 Prices: ?C 5 1 3 . 90/h ? 32. 2 5 30 (/> o N5 CJl CO ^1 fe Vr'.' . ft W-3', w1 \>?3 .. ., 8 IW pp$K m *\.- -?'? 'd-rt-.V-lg? tibr' ' "---iw ; ;-4u >>: k.-s3k Iglf "'i , .VS S-iuV- -*i Jl;?, f'- C** '~ ?:'U) Vtftf' ',,^v>.;i,; ft'?,' '*' t > ifii * ' ,;V,' Ci?,. , -'-i^ ' . i.t.i ,Tj. " r. ' * .- . ' ..... i*. Scientific and Technical Assessment Report cr. Polyvinyl Chloride >. ^ ` ^ Snvironmenta 1 Pro*tcuoj Agency, Fesear ch Triangle Vinyl Chlo::ii ' Par &, S'. c. ' arc Fir.ai rapt. CblOSdJ Fid: 06T, 06 J, Dec 75 125p` P.ept No: E?A/6G0/6-75/00u tor. it or: 18 Sea also PB-246 820. 110, 57Y-, 57 U , 68G`, 6oA, ouD J?.A:750c Anstnc:: Vinyl chloride (VC) is a chemical or widespread industrial ana commercial use. Occupational ejcperier.ee and experimental evidence, strongly indicate , that it is a carcinogen. Additionally, there is.v. experimental evidence that indicates that it may be a teratogen and mutagen. An increased incidence of liver angiosarcoma, excessive liver, damage," and acroosteolysis has been reported among VC workers, ir.c the frequency and severity of the liver pathology is related to the length of exposure. The principal route or exposure is tbougie tc be air inhalation. Sources of increased importance rcr the general population include-"-!"ood and water. Tumors at multiple and diverse sit=s have oe-ir. observed in all, species of experimental annals tested for carcinogenicity by.inhalation and ingestion of VC. In addition to me 'health effects of, VC, this document also considers tna sources, . '.istrinution , and control technology. ' 't'- 4j ' i-. * Descriptors: `Polyvinyl chloride, `Vinyl chloride, `Toxicology, `Industrial medicine. Air pollution. Public health. Liver, .tali grant neoplasms. Carcinogens, nutagens, water pollution, Food cr.ams, Humans , Laboratory animals. Experimental data, Chemical compounds, Chemical ..industry, ,,Identifiers : `Air pollution e f facts (H urnan.s) , `Envircrm :rt al health,-Teratogens, Air, pollution control, water pollution efacts (Humans) , NTISEPAOP.D Hi IT"' ' ' ' `T'V Fv; ' : '3 He a Irk ; ' Hazard Svaiuation/Toxicity Determination Report ii,'3i. ; ''V'74-94-253, Armstrong Cork ccmoar.y, Jackson, hississinoi ;.'... . , - ' '" y$- ' - * ' ?;*;: . . . / i#.?/.-':-.' ? ' National Inst.' cor-'bccups tior.a 1 5 a f : t v and Health, Ci:.c::.r.i;i, 3-- lK. * /(.1wvl o^ . ,*77C66 )v rf;#': a 1""^^ '. Pi & Kt fe'C' ar.<;ia ifi '7. Finii,','r.= pt. Dec 74-jul 75 T Flesch, ..Jerome ?., Rostand, Robert A. C 610 a L 3 f'U: 06 J, 067, 570, 9UD, 6BC, D ec 7 5 16 p Kept No: N103H-73-HH3-74-94-253 Monitor: 14 See also P3-249 <02. f,?AI760S .. . ' 1 ;.7 . ,, ., ' . } jy" ' -j, abstract: An environmental-medical evaluation was conducted by :;iqsh at a plant manufact urir.y vinyl asbestos floor tiles. Environmental air samples were obtained, medical records were reviewed, and non-diracted medicalint erviews; were administered. It was determined that exposure , to airborne chrysoti-a asbestos was in excess of the proposed CJ3HA standard ini that there was a potential for exposure to trace concentrations of airborne vinyl chloride monomer, Worker exposu: ;s. tc otner toxic materials were nelow levels believed to be notentiaiiv toxic, Review of medical records revealedi.no findir.es suggestive 1: , lung cancer (noting that malignant manifestations of asbestos e:<nosu:c may take 10-40 years to develop after the exposure hasceased. `f > r.T 7--; ? 'V jM# u pf S' ^ , ' !> m frc"r?-*! 'Hazardous . .materials, 'Industrial medicine/ "Vin'vl chloride, 'Asbestos, "Silicon dioxide, 'Limestone, Toxicity, Criteria^ Inspection, standards. Recommendations, Industrial hygiene, Industrie' , atmospheres, Exposure, barium, Lead (Metal) , chromium' zir.c, Titanium* Carcinogens, Interviews '-/ jp1 -h^ 1 ,^isrs 'Occupational Sarety and Health ' Act of 1570, *7oxic hazards, ;*.Air sampling, Stha ne/tr ichloro, t.'TliH-WOSH ':,?3-249^U33/UST N7IS Pricer: ?CS3 . 50/.4 F S 2.2 5 km-:h s. #' (*&*:,1 It 5,<SS!:U(;' "a k- ,y i^ 1 :?'v., \h~' Vy 7-1: d^fe'OvV' 20 "7'_ .'i 'z a) - , ;' * *' i- ,.' :'Y: 3sut>'' ar^S# "-! t %*'*>,- `nkilr^ , .i-.w,: /4',`vy *.\;,v- > '\' ,- ,-;;f ' ' <.' ,* 'i -. g^; - ,,> . \, *4.: :.v,, , , - ,, ^y '.-<i.;;. . . >'.. " r^yTj> , .,, /iv-,.* ' ` -'* '., ,1 -. . - -' -. Y- - ..> ,';' v. ;^?V`'.` . >Health igiiazar 1 .Vf. ' '.<TM7'5-:8 1-2 5'2,\'Artex $!;- ' r :._v " Hational^Inst. , V - (-H0 766) v Zvaluation/Toxicity Detiirniir.at.ion Report i Wanuf actur m g .Com pany, Inc., Overland Parx, Kansas %- $.B'.iV: , ''- 1 ,: - - ' J ' i-' forYoccupational Safety and Health, , Cir.cmr.ati,"Onto . rf j;.. a .j3 fclfe fct4:K$l .fr.r !i;. Final rept.' .lay-Jur. 75 , fi tiervin, '"Raymond L.. |:C6 10UL2 cFld: 0 6.J, ' 06T , '5 7U , 94D, I*. Dec 7 5 11 p .v/ V , ,Y '. Rept He ::i'H:6sH-TP-HIi2-75-B 1-252 Mon itor :}\18 'f y;-: ',. . . *. Se* also P3-249 431.' 68G GRAI76Q8 ` ,vf t, > .yM .j" * /bC*' ' / f r' X- Jcf-'"'' '.`If ire^? ' ty. ill* v r '%% ixicV ,. 1:4''1 '. Ahstract : "A^haaltn ^hazard evaluation was conducted by HIOSH at a plants: . ^ ` nvolvedi'Vin , the^.silk /screen .dyeing of decals onto various 'textile^;.. arments'^Ylt vas^deterained that employees in the ,twc aain productror.j>:, f, ,_reas veral'' not imposed to toxic concur.trations of vinyl chloride . and;/-;'. * ,;'org anic Y.sol vonts,'1 including ' 1, 1,1-trichioroethar.e , toluene , xyien a,\ , ' and 'petroleum naphtha. It was further determined that the clean room ope rat or {if va s exposed to potentially toxic cor.cer.t rations ^o .o rg an ic ^ : solventsffrom cleaning silk screens with an organic solvent containing priaarily naphtha. " .<- ';.;' f ' Descriptors: wHazardous materials, ^industrial medicine,. *Vmyl chloride,- *Toluene, ^Xylenes, Toxicity, ' Criteria,^ Inspection, .-^.Standards, Recommendations, Industrial hygiene. Industrial atmospheres Fumes;. Organic solvents. Exposure, Chloroform, Naphthas, .Textile "industry .' ' : --a--' J/'" Identifiers: ^*Occupational Safety ar.d Health Act or 1970, * .o:<ic 'A1 hazardsit NTISHEWOSH ; .. V P3-2U9 4 32/6ST - - V, , r.`*H1 va^,. & HTIS Prices: PCS3.50/hFS2.25 v *H>V; , ' , -< IP? Vs > :{'X'.'v. > ' i*'-*- V :,j* ',h - -' *' ^ /> V" 1 Vv- \ ..... r 'A ,;7 .'j ; . "r ...W; ' *i n rt' . . . ' i . ..7:u ' ;-pj <r a .. i:Y/>y;r. Y- '. fa-j ' >; |r3 si '; N- i' If I ;' -. s ' -t* [JSK'ty I**;?,-.*jrl , J ' i ' ' i, ``UK ,'*:' ! ,v - , t, ,'! ': - -.' ` -< ' * '' " C Health ;i,iiir 1 ivalu aticn/Tox :ci:y Oet-rmi n at r : r. port 7 4 - -2 i, !J 2 ,9 5- 2 4 6, Oriels sill's Piefc-N-Pay t i r < ; t, Vo. r, 'no Hal jV.s, Ohio, Madsen's Valu Center. Har,/.a:o, Mir.r.ejot i, ar. : Ccnpa.uy, Logan, rfest Virginia ;.r n : Va-lonal I r. 3t. (J9 0 K>r,) for Qccupa tiona : 3a :ty ar".Ji! '! i a : * r ^ * Pinal r?pt. Vanlervort, Robert, Brocks, Stuart M. ColOuju ? 1 1: C' 6J , OfeT , 5 71), 3UD, odG G."A:7h:ri ' 7^ 75 31 p dept No: Nlb3!i-r3-iIiIE-74-2tt-246, N 10 S H-T 3- ill! t-7u - 9 2 - 2 4 . Monitor: IB Also availaole as report no. N I0SH-T3-MHE-7t-4 5-2a t>. 3=-? also 925. i ; Abstract: ;At the request or employees from several supermarkets, "los;; conducted health hazard, surveys to evaluate exposures to sunsta r.r emitted by hot-wire cutting of polyvinyl chlcri-le meat-wrapairj filer and thermal activation of meat package price libels. Meat : epi r rn- employees pulmonary were interviewed a r.d given physical examinations function tests. Blood samples were --Iso obtain..:. Environmental air sampling was also conducted. Based agon th-i-: medical and environmental data and upon ctr. = r information reiirdi:. : ..i aat'. wrapping and labeling operations, it was determiner that ho* wi:.- cutting of pvc meat wrapping films ar.d thermal activation cf prio_ iabels can release irritant substances into the worx environment, health hazard exists "from vinyl chloride monomer however. Descriptors: "Hazardous materials, "Industrial memcme, "VtnviJ chloride, "Hydrogen chloride, "Polyvinyl chloride. Toxicity, criteria,! Inspection, Standards, Recommendations, Industrial hygiene. Industrial! atmospheres, Exposure, Composite wrapping * gCjj Identifiers: "Occupational Safety ar.d Health Act or hazards, Air sampling, phthalic anhydrides, NTlSliCNOSH ?b-249 U26/8ST N7IS Prices: PCSu.00/KFS2.25 t73. . c x : ti hV' r\' - Ipri' '} j |;1 >..' K&'Vjur'jKS 30 t iiazar 1 5 vn 1 iijt, io.o/Tox ici * y Da* e :j: rat i o r. 7 )- 17 3-244, sender. Chemical csajar.v, La omir. i si e r, '* rr: ^ ~ - d. Otrno 44 r4o4 National Inst. tar Occupational Safety ami Health, C::.c:;.r i * i, Ir.io. (JJI 736) Final rept. Poiakoff, pnillip Lae 26 1 04Js Fid,: 06J, 06T , 5 7'J, 94D, D ec 7 5 14 p .lent he: N IOSil-TP-HH E-7 3- 17 3- 244 ton it or: 18 63d '; r A I 7 *1 :J -l Abstract: NluSii or. vestiqat <=i ar. alie-jed health hazard ::ci trypsin, a oroteolytic enzyme, ar.d 'lekal 3-7b, a ssuurrraacct arc.t, ir. a pi m an ur act ur in j polyvinyl chloride resins. Employees '-'-re a inr.ister ed non-airected medical questicnr.aires, skin t-'sts and pulmonary : motion tests. at van determined that a number or employees hao ae1 o: -<: 1Z ^*.^3 0 JiC sensitisation to trypsin, resulting m respiratory im oai ton r. t. Some employees vno have- not beer, se r. si *1 zu i have still : eveloued milill ! 'inner respiratory irritation. leternined that several employees who handled the our :,-_ot art NtX'.i 3-Vd had psriodically experienced upper airway imta*ion, ;ajjin and shortness of breath. This problem was yuijad to r.- the resul' poor work practices and no serious health cor.se ; ience; exposure were observed or anticipated. Descriptors: `hazardous materials, `Industrial me :irir.-, `polyvinyl chloride, `Trypsin, Surfactants, Toxicity, Criteria, Irs:=ctior, Standards, Recommendations, Industrial hvqier.e, Industrie^ j tmcspher-., Exposure, Respiratory system. Chemical industry, All azoic iis&aaes s. i*' Identifiers: `Occupational Safety a.nc Health Act or l -71, `Toxic hazards, NTISHS'w'OS.d ? 3 - 2 4 9 424/357 NTIS Prices: PCS3 . S0/V.F3 2 . 2 5 S R&S 025444 r;*-' m ' l'-V ,j' ' i ` . ." , *' 4 * `~\` '/ v* - /?. . /'v.: '.v?1 &'..4`;#; ded-tn Hazard 75-12C-22C, St or ji Z v a i u a t i o n / T o x i c i * y 0 e t -r- r a i r. a t i a r. h ;>o r *i Products Company, ?ilo Alto, Cilircrr.ii national Inst. (J90 766) for occupational Safety and Haa. Cincinnati, Inic, final rent. Oxa wa, d e 1 v i n ., Co 1 04 02 Fid: 0 6 J , 067 , 57tJ, 940, Seo 75 Sp Saar, iio : .`JIOS H-7R-MH S-75- 120-220 Monitor: Id See also PD-249 uOI. oor, <J H A17 6 0 y Abstract: NIOSH conducted a health hazard survey at a pla.tr prcu-jcing finished cables, A 3mail extruder is used .to coat wire wi-n ?7C plastic or other coating materials. Environmental air samples v^re collected icr vinyl chloride analysis and no rietectaois amounts wsrs found on any of the samples. It was concluded that a potential health hazard from vinyl chloride gas does not exist under conditions round during this evaluation. descriptors: `Hazardous materials, `Industrial medicine, 'Polyvinyl chloride, `Vinyl chloride resins, Plastic coatings, iias-js, Carcinogens , Toxicity, Criteria, Inspection, Standards, Industrial hygiene, Industrial atmospheres Identifiers: `Occupational Safety and Health hazards, Air sampling, NTISHSWOSH or 1*70, `Toxic P3-249 UC0/3S7 NTI5 Prices: PCS 3. 50/.HF 12.2 5 R&S 025445 y>ti t im: kmi*. 34. .< < V'* lfSF m / j i. Final rept. Ruhe, Raymond L C6134D1 Fid: Q6J, C6T, 5 7U , 9UD, 3ep 75 6d 3 ap t .Vo: N:0SH-Tr;-HHE-75-94 -2 19 monitor: 13 See also ?0-249 400. b HG 9EA:79C3 {./Abstract: A plant manufacturing polyvinyl chloride tel^pt.or.-= svitcho ox '^covers by mains of an injection molding process was mves tiga t ad ay .,,1JI03H to evaluate exposure of employees to vinyl chlcriie. Air sanpl ;Jvara obtained for vinyl chloride analysis and mere wre no iitsctao amounts of vinyl chloride found. Nor.-d iracted medical guest lor.r.air u%re also administered and on the basis of medical a:.: ir.v irtnment al data, it was determined that a healtn hazard dio r.ot exist at the ti of this evaluation. Descriptors: "Hazardous materials, `Industrial madicir.s, `Polyvinyl chloride. Vinyl chloride resins. Plastics industry, carcmog ar.s, lasec , Exposure, Toxicity, Criteria, Inspection, Star.darus, Recomaenuitior.s , Industrial hygiene. Industrial atmospheres Identifiers: `Occupational Sarety and Health Art of 1970, Tox hazards. Air sampling, NTISHZWQSH PB-249 3 99/7ST 1!IIS Prices: PCS3.59/MFS 2.2 5 ii *' ;! ij i1 \ ii i ! He a. 2.1k Hazard 7;- 1 ] j-i id, Evaiuutior./Toxicit y Determ nation . ~*port Tire and Rubber Company, Marion, I:, ii isi J a cion a 1 Inst. (J9C 76o ) for Occupational C Co10-C4 A u7 5 ut. Dec 7 4 - J a n 75 . Paul, Cormer, John w. Jr rid: 0 6J , 067 , 5 7'J, 9 4 D, 2 Op :i:os-i- 7S-HH E-74- 1 1B-21H n Pd-249 3 99. - i. r j R A17 b C d Abstract: A plant which Manufactured molded urethane cusnion.-; m automobile seats and bulk urethane foam ror a variety c: cor.mem a. purposes was investigated by KIOSH to evaluate employee exposure to toluene 2, 4-diisocyanate, polyvinly chloride resins, ana mold releas^wax. Environmental measurements were performed, medical interviews ;: pulmonary function tests were administered, and vorx practices wer-: observed. It was determined that airborne concent r a' i ons or nine:.-" 2,1-diisocyanate are potentially toxic to employees at the roar, litin the slab Department but not in tne Mold--; "oar. Department. Particles of mold rel=ase wax were found to cause temporary irritant symptoms in some workers. Exposure to polyvinyl chloriie rasms not beiievad to pose any health hazard under conditions onrervi: a during this evaluation. Descriptors: `Hazardous materials, `Industrial medicine, `Poiwin/ chloride, `hold release agents, Plastics industry, Is ocy am. at Urethanes, Waxes, Exposure, Molding materials, Cases, Toxicity, Criteria, Inspection, Standards, Recommendations, Industrial hyjiun-t, Industrial atmospheres. Carcinogens, Vinyl chlorine resins Identifiers: `Occupational Safety and Health Act hazards, `Isocyanic acid/(methylphenylen=-ester)di, 19 7 0, Toxin' sa j,ic, ;, "M ! '% 'C'Z V*, i4ff s '.> 4y\>sjG ;:;1 j^` [i/.r^i'A ' ' ; W'WW ;.' '-$"<. v %rr? f `i* .. <-, .v, ' vie- Health Hazard tvaluation/Toxicity Determination ', 74-59-217, .Joodyaar Tire and Rubber Company, Sr. Marys, Chic Nat ional Ir.stT for Occupational Safety and Health, Crr.cinnati, ono. {39C 766) 7ir.al rent. ,Jul 74-Mar 75 Vandarvort, Robert C610UC3 fid: 06J, 06?, 57U, 94D, Aug 75" 6p ' Sept No: NIOSH-??.-HHS-7 4-59-2 17 Monitor: 1*3 See also PD-249 390. 6<3G GSAI76C3 ' Abstract: NIOSH evaluated employee exposures to vinyl chloride monomer in the mixing and film casting processes during the manufacture of clear ; plastic films by the solvent casting method. Air_saaples vara obtained and no detectable levels of vinyl chloride ver= round. It as determined that a health hazard did not exist at the tine of tms evaluation. Descriptors: "Hazardous materials, "Industrial meuicir.i, */i;./I chloride, "Polyvinyl chloride, Plastics industry, Carcir.og an s, Toxicity, Criteria, Inspection, Standards, recommendatijrs, .r.dust -- dl hygiene, Industrial atmospheres Identifiers: "Occupational Safety and Health Act of 1970, *.cxic hazards. Air sampling, NTISHEWOSH PB- 249 3 97/1 ST NTIS Prices: PC S3.50/MFi2.25 R&S 025448 II :.i ' 1 - . -7.^.. 37 -A1 y.&v'-fct SFitS P'tM & `il >vi' :i&f| m $| ' \4A^VBH * R M ' "` v/'jf/ 1 ' V <"Pi&' ' >' , ;-\``Jy''.^*uhJH?_?-<e_.*'-\_<-''_j'iI.l_yi-_''-*._\4_&h"&' V~,-?.H_:<a__z__a_r_d._ . Svaluation/Toxicit y Di:s:a:r.auor. 74-125-215, tona-yhan Company, D;nv=>:, colcra<.c insr. for Occupa tional Safety and Health, C::^:.::.;::, 3*J0 766) cs--li.rt'i,?i.nal rent. Dec : Counter, Bobby J. -, C6 1OUC1' Fid: ' Jul 7 5 ,,,8? Sent No: NIOSH-T! Monitor:, 18 \See also . PB-249 Abstract: A hhee> alth worker 'exposure pelletized, and hazard survey was conducted oy :`>2C-;: to Descriptors: ^Hazardous materials, 'industrial medicine, */ir.yi chloride, resins, 'Polyvinyl chloride, plastics industry, Carci:.,, l-ns, Gases, "Toxicity, Criteria, Inspection, Standards, ecc.T.n enuations. Industrial hygiene, Industrial atmospheres t Identifiers: 'Occupational Safety and Health Act o: 1-J70, `.exit y, hazards. Air sampling, NTISHE'JOSH ; P3-249 395/5ST NTIS Prices: PCS3. 50/:iF52.2 5 R& s 025449 . ,, .y.' >' .1 It.V- ' *f >'"' -,^nr , ; mss BVJl IffM.; 1 El m ic ,lieelth Hazard Evaluation/Toxicity Determination ,*v >75-20-209, Eichdel Corporation, Carson City, Nevada Raport, ::.!:. i- if'national Inst. v (070 766) tor Occupational Sazety and Health, Cir.cmr.at_, Final re?t, Mar-Apr 75 Okawa, Melvin T. j C6 1 0uA3 Fid: 06J, C5T , 5711, 94 D, 66G GHAI76C8 u Jill'. 75. dp '."apt No: NIOSIi-T?.-i!HE-75-20 -209 ,ti monitor: 18 f,f Sea also PB-249 3 90. .^Abstract: A regrinding operation in a plant manufacturing ^o!i=d f plastic valves was studied by NIOSK. Based upon environments.^sir sampling measurements, analysis of work practices, and on avanan-e ? information regarding t hs toxicity of vinyl chloride. determined that a potential health hazard does erist. Descriptors: `Hazardous materials Industrial medicine, *7 my I chloride, `Carcinogens, Toxicity, Criteria,^ Ir.specti si * d r. r "i s / Recommendations, Industrial hygiene, ndustria'l at.tospner-s, Plastics, ' Valves, Moldings Identifiers: `Occupational Safety and Health Ac- o: 1*70, *.ox_c hazards. Air sampling, NTISHEHOSH PS- 249 389/8ST NTIS Prices: PC$3.50/MF12.25 ikhh : R&S 025450 i#; 39 i'ijvV''dX'i'Xi ' . V: t?f V^;i,, v,.r-. t l I `,l L.lf*T . ir J v'^>r*'V *55333*2^^ Health Hazard Evaiuati on/Toxicity t erminuti; -e '-o: *. i. /5- 1- 1 - National Inst. (Ji0 766) for Occunj tiona 1 Safety and Heal*.-., Ci:.cci r. n 1t1, Pinal rept. Okawa, he Ivin I. ColOJIb "1 i: C6J, 06:, o 7 LI, Hay 75 6p ^pt lo: NIUOH-Tr-HHh-75- 1- 194 Monitor: 18 See also PR-249 J75. rj r D , QaC, 03AI7m: 8 Abstract: Ar. extrusion operation fcr wire cable was s*::ie: by to evaluate employee exposure to vir.yl chloride. I* -is Interim-ad that vir.yl chloride gas may be potentially toxic at th; o orcer.t r i* tons measured during the NIOSH evaluation. This determination was :ias~: or. exposure times, work practices, and the carcinogenic pot = :.tni o; vinyl chloride. Descriptors: `Hazardous materials, "Incut-trial chloride, `Carcinogens, `CaDies(Ropes), Toxicity, C: i , Standards, Recommendations, Industrial hygi atmospheres, Plastics, Wire, Extrusions, Exposure Identifiers: `Occupational Safety and ' Healtr. Act hazards, N'TISHEWORH 19 1C , t* PD-249 3 7 U/03T NTIS Prices: PCS3.50/HP52.25 I \ i Health Hazard E value t ton/Tox icit y Deter air. at ic n : e nor t I i - * 7a-134-193, ?HC Industries, Inc. , Casacr., Ne*< Jersey national Inst. for Occupational Safety and Health, Ci: (390 766) Final rept. Ji1les, Dawn C610JI3 Fid: C6J, 06T, 57U, 9UD, Hay 75 6p Sept N'c: !JI03H-Ti1-HHE"7U- 134- 19 j monitor: Id See also P3-249 J7u. 66(1 ShA:7hCU Abstract: NIOSil conducted a health hazard evaluation at a plant 'men manufactured handies from PVC resins. On the basis ci envircninenta- sampling conducted at the molding and extrusion processes, it as cj,3-mined that a health hazard from --xposure v*../l c.._o--. monomer did not exist at the time of this evaluation. DescriDtors: *Hazardous materials, Ir.d ust r ia ' :e , v _. chloride, `Polyvinyl chloride, `Carcinogens, .oxicity, ^Cr.tj-_i, Inspection, Standards, ?. eco mmendaticns, Industrial hvgi=r.e, In.urtzii- ataojoheres, Extrusion, Exposure, .tellings. Polymers .c Identifiers: `Occupational Safety and Health Act or 1-J7`- : ic hazards, Air sampling, dTISKEo'OS ii P3-2U9 37 3/25T NTIS Prices: ?C33. 50/.HFS2. 2 5 R&S 025452 4I VC-PVC Crisis: A Systematic Approach to Toxicolcytea i .. ^ i. * r* .< .j California Ur.iv,, liar icel'jy Kland, N. J. A7265FJ Fli: CAT, 57Y A u 'j 7 5 3 p Sept N'O : CON F-75067 3- j Contract: 7-7405-ENG-ad Monitor: 13 Laorer.ce EPAOICa Berkeley Lab, (i 11 Abstract: For anstract, see S ? A Cl Cu, number C5i2`i. Descriptors: (*PVC, ^Health hazarcs), (*Vinyl monomers, i ), (`Carcinogens, Health hazards), (orcanic chlcrr: Health hazards), Bioloyical eftsets, Carcinomas, Hume: Neoplasms, Peviews, Toxicity n i7.i: : Ob po ir. : 1 x t i o: Identifiers: SRDA/560306, NTISEF. D A L3L-3275 NTIS Prices: PCSU.00/MF32.25 r jo A::-vn/icv availal'-- \A 42 .1 R&S 025454 _____ _ WMmm ^*v*r*w- -'^r i '*;!, \ Epidemiology Studies. Task III. Vir.yl Chloride American Public Health Association, Washington, D.c.'Environmental Protection Agency, Washington, D.c, office of Toxic SuDstances. Final uept. AUTHOR: Landau, Emanuel, Brinkman, Charles ?., C53 75H 1 FLD: 06J. 5 7 vJ , 60G* USG3DR7605 Nov 75 1C6p* CONTRACT: EPA-63-01-2490 MONITOR: EPA/560/6-75/002 Kanos, Hichu-as n* ABSTRACT: Using data from the 1 970 Census of Population estimates of the number of people living withir. a 5 mile radius or industrial plants producing vinyl chloride and vinyl chloride resins was prepared. Findings are reported. The sex, and age characteristics are pro vided. DESCRIPTORS: 'Epidemiology, 'Vinyl chloride, 'Industrial medicine, Public health, vinyl chloride resins. Industrial plants. Exposure, Populations, Demography, Tablas(Data>, Environments IDENTIFIERS: NTISEPAOTS P3-24B 426/9ST NTI3 Prices: PCi5.50/KF32.25 .a .1 _ Mm--;ma k:-*pfef: ' : ;.' ^ ^ . V :;* ' ' $><'! if`;r5 \U' i-- , - 1 -^.`r'ci wl1 / f`: "1 ..-. L V1'4: ' r>w.. ,\ - ;$.. ' `:' .;'!f|"YIt*h'^i' %!^az i`:'d ";' s va1 uatlcn/Toxic i t y Determination Report 74-151-1:1 1, - "West er'ii'.'iFor qe Corporation, Colorado Springs, Colorado Jnia-tional'"'V1^> *Inst. v'.` 1 *4 for Occupational Safety and Health, Cincinnati, {`J9C 766),, V -y t^,y Jr V,' -'Hv'-v*-, -W.J ,. iFinar"'rspt. 1 Jp1' AUTHOR: Butler, George,! J. C5793I1 FLD: 06J, 06T, 57U, 94D, bdC USGRDS7604 Apr , .75 " 7p 4, .R2PT .`JO; "`NIOSH-TR-HH 2-7 4-15 1- 1 d 1 monitor:'lie Ohio. t<s 'ABSTRACT :f!; ,'iIOSH . conducted an environmental survey of a forge manufacturing hand tools. Employees were exposed to vinyl chloride gas in. the asaambly and packing area arising from the vinyl chloride coating .^.applied to. packing containers. ' It was determined that ^employees were exposed to potentially toxic levels of vinyl chloride ..J-at. ..the .-'time of this :/ val uation . Recommendations were made regarding f"'reduction of airborne concentrations and the use of respiratory '.^protective equipment. , DESCRIPTORS: 'Hazardous materials, 'Industrial medicine, 'Vinyl chloride', 'Polyvinyl chloride. Toxicity, Criteria, Inspection, Standards, Recommendations, Industrial hygiene. Industrial atmospheres , Protectors, Exposure, Forging, Threshoids(Pereaption), Toxic tolerances. Films, Packaging materials. Respirators IDENTIFIERS: 'Occupational Safety and Health Act of 1970, 'Toxic hazards, Metalworking industry, Maximum permissible exposure. Air sampling, NTISHEWOSH 30 fio CO 0 NJ CJl 4s 01 Ol v' k: t - >;"4 'Cftji a, T54 rf /' is ; X *`! w-7 * X5 m >'<4 ,>'y y > _i`;V .A 1 ri ,, 'C5793Hu' Anr 7 5 2E?I SO: ^OSITOR: '.FID: C6J,"06T, 57U, 94D, 7p NIOSH-TR-HHE-7U- U9- ISC 18, 6SG -JSGaDP.7faC4 ABSTRACT : The environmental survey of a plant pot9ntially;,.hazardous levels of vinyl chloride gas. It was recommended that airborne ' concentrations of vinyl chloride be reduced to non-detectab le levels ,-.nd that respirators be worn by exposed employees until control measures are effective. DESCRIPTORS: "Hazardous materials, "Industrial medicine, "Vinyl chloride, "Polyvinyl chloride, Toxicity, Criteria, Inspection, Standards,'Recommendations, Industrial hygiene. Industrial atmospheres , Exposure," Evaluation, Plastics industry. Respirators, Gases, Surveys IDENTIFIERS: "Occupational Safety hazards. Air sampling, NTISHSWOSH >. " . and health PB-2U6 U96/4ST NTIS Prices: PCi3.50/MF52.25 Act of 1970, "Toxic 'I : r. -'ij #4' ii f* - \'lreaith Hazard Evaluation/Toxicity Determination Report 7u-g6-f7j, ^'llichdei Corporation, Carson City, Nevada '.National ^Inst. '`(39 0 766) f for Occupational Safety and Health, Cincinnati, Ohio. > Final rept. . AUTHOR: Ottawa, Melvin T. C5793H2 ' FLD: Q6J, 06T, 570, 9uD, Feb 75 8p F.EPT NO: NIOSH-7 3-HHS-7U-96-1 73 .MONITOR: IS `sfy 6 3C, USGRDr<760u A3S?RACT:: A plant involved in injection molding of polyvinyl chloride was studied by NIOSH to evaluate employee exposures to vinyl chloride and trichloroethylene, which is used as a degreaser. It was determined -that a potential health hazard from exposure to vinyl chloride aid exist in the Eegrind Soon, and a potential hazard may also exist in ...the injection molding areas. Trichloroethylene was judged to be not toxic at the concentrations measured at the degreasing operation. DCS CRT P70RS: 'Injection molding, 'Hazardous materials, 'Industrial medicine, 'Vinyl chloride, 'Polyvinyl chloride, 'Chlorohydrocaroons, . 'Degreasing, Toxicity, Criteria, Inspection, Standards, Recommendations, Industrial hygiene. Industrial atmospnaras. Respirators, Exposure, Protectors, Plastics industry. Evaluation, Toxic tolerances. Thresholds(Perception), Surveys, Gases IDENTIFIERS: 'Occupational Safety and Health hazards, *Ethylene/trichloro. Air sampling, exposure, N7TSH2W0SH Act or 197U, 'Toxic Maximum permissible PH-246 49U/9ST T NTIS Prices: PC53 . 50/MF S2.2 5 i *,'5 x-f 33 CO oroi -fe Of x Health Hazard Zvaluation/Tcxicity Determination Beport 7U-U9-1B9, hew York Telephone and Telegraph Company, hew York, N.Y* National Inst. for Occupational Safety and Health, Cincinnati, Ohio. (390 766) Final rept. AUTHOR: Straub, Wesley E. C5793H1 FLD: 0 6.7 , 067 , 57U, 9UD, Apr 75 7p r.EPT NO: NI05H-TB-HHZ-7u-a9~189 MONITOR: 18 63G U5GRDF.760U ABSTRACT: NIOSH conducted an environmental survey to determine employee exposure to vinyl chloride, styrene, benzene, and hydrogen chloride during the application of heat shrinkable,tape to telephone cables. It was determined that air concentration levels were below detectable levels for all substances tested and therefore were judged to be not toxic under the conditions noted during this evaluation. DESCRIPTORS: `Hazardous materials, `Industrial medicine, `Styrene, Benzene, `Hydrogen chloride, `Vinyl chloride. Toxicity, Criteria, Inspection, Standards, Recommendations, Industrial hygiene, Industrial atmospheres, Evaluation, Exposure, Coatings, Polyvinyl chloride. Thresholds(Perception), Toxic tolerances IDENTIFIERS: `Occupational Safety and Health Act of 1970, `Toxic hazards, Air sampling, Maximum permissible exposure, NTISHSWOSH P3-2U6 -93/1 ST NTI3 Prices: PC3,50/.NF S2.2 5 4 >;i-X Health^'.,. Hazard E val ua t i on/To xici t y Determination Report 74-65-195, y.. H. Gall!'Comp any, Lancaster, Pennsylvania . National Inst. for Occuoa tioria 1 Safety and Health, Cincinnati, Ohio. (390 7fa6) Final rept. AUTHOR:, Straub, I'esley s. C 5 7 9 3 G u . TLD: 06J, 06T, 57U, 94D, Apr 75 lOu I. EPT NO: Nl6sH-TR-HHE-74-85-185 MONITOR: 18 6dG US G PDF. 7604 > A35TRACT: A health hazard survey was conducted by NIOSH to investigate a potential health hazard at a company performing lamination of printed material on a job basis. The laminate is a polyvinyl chloride basad product, which is layered with the printed material, then the layers are heated for curing. It was determined that a potential health , hazard exists at the lamination press from vinyl chloride gas, based on environmental measurements, observation of work practices and a review of past medical reports. DESCRIPTORS: 'Hazardous materials, 'Industrial medicine, 'Vinyl chloride, 'Polyvinyl chloride, Toxicity, Criteria, Inspection, Standards, Recommendations, Industrial hygiene. Industrial atmospheres , Exposure, Evaluation, Gases, Laminates, Carcinogens, Liver, Thresholds(Perception), Toxic tolerances. Ventilation, Surveys ..IDENTIFIERS: 'Occupational Safety and Health hazards, Lamination, Air sampling, Cancer, exposure, NTISHEWOSH Act Ot 1970, 'Toxic Maximum permissible P3-246 ,492/357 s t. NTIS;Prices: PCi3.5G/HFS2.25 Art 3D fio C/J O ci\n> <con Health Hazard Evaluation/Toxicity Determination Report 74-7 1-14 2, Eelco Remy Division, Anaheim, California National Inst. for Occupational Safety and Health, Cincinnati, Ohio* (3 `3 0 7 ft 6) ' Final rapt. AUTHOR: Qfcawa, Melvin T, C5793G1 FLD: 06J, 06T, 57U, 94D, Sep 74 9p PSPT NO: NIOSH-TR-HHE-74-71-142 MONITOR: 19 6BG U3GKDF76Q4 ABSTRACT: An operation in which polyvinyl chloride was being used to manufacture the separators used in automobile batteries was studied by NIOSH investigators. It was determined that vinyl chloride vapors were not toxic- at the concentrations measured during normal operating conditions.This determination was based upon the environmental levels of chloride, the conditions of use of polyvinyl chloride, and current information available on the toxicity of vinyl chloride. DESCRIPTORS:', `Hazardous materials, `Industrial medicine, *Vi.vyl chloride, `Battery separators. Toxicity, Criteria, Inspection, Standards, Recommendations, Industrial hygiene, Industrial atmospheres , Vapors, Exposure, Evaluation, Electric batteries IDENTIFIERS: `Occupational Safety and Health Act of 1970, `Toxic hazards, Battery industry, Air sampling, NTISHEWOSH PB-246 409/9ST NTIS Prices: PC53.50/MF52.25 Health Hazard Evaluation/Toxicity Determination R?jrr' Ethyl Visqueen Division of Ethyl Corp., Terre Haute, .ndiana National Inst. for Occupational Sarety and Health, Cincinnati, Onio (390 766) Final rent. A'JTHOR: Sutler, George J., Uodner, .\rnold H. C5793E2 F LD06J, 06 T, 5 79, 9"D, 6 6G IJSGRDR7 604 Nov 7 u 10 p REPT NO: NIOSH-TR-i!HE-7U-29 - 16 1 NON 1703: 18 ABSTRACT: A aar.ufacturer of polyvinyl chloride pipe was investigated by NIOSti to evaluate worker exposures to polyvinyl chloride. Crystals of polyvinyl chloride resin are nixed with other materials and then extruded into pipe. Air samples were collected, workers were given medical interviews, and blood samples were taken to be analyzed ror serum q 1 ut.amic-oxaloacetic transaminase. It was determined that a health hazard from vinyl chloride monomer did not exist at the time ot the survey but that a potential carcinogenic hazard did exist m tne hlendinq room areas of the plant. DESCRIPTORS: 'Hazardous materials, 'industrial medicine, 'Polyvinyl chloride, 'Vinyl chloride, Toxicity, Criteria, Inspection, Standards, Recommendations, Industrial hygiene. Industrial atmospheres. Evaluation, Surveys, Interviews, Blood analysis. Pipes(Tuoei), Carcinogens, Plastics industry. Dust, Statistical data, Chemical ind ustry IDENTIFIERS: 'Occupational Safety and Health Act of 1970, 'Toxic hazards, Air sampling, KTISHEWOSH PB-246 482/U3T NTIS Prices: PC S 3.50/.1F $2.2 5 30 .its Toxicology of piastic Devices Having Contact with Blood Children ' s Hospital .ledical Center, Boston, das . * Nationa 1 He a Lur. u 1 r. 31. Bet hesd a, Nd. [062 790) Comprer.er.sive rent, sau 72-5ep 75 AUTHOR: Kevy, Sherwin V., Butter., Lawrence N., C57 51 M FLD: C6T, 131, 06L, 57Y*, 710, 95C let 75 112n* CONTRACT: ?H5-72-296d EON ITCR : N _ H/N H LI -7 2 - 2H 6 9-C 3 Se" also ?3-2h4 753. J a cod son, day' 3. J5GRDR76C3 and ABSTRACT: 7 me objectives of this research were twofold: (1) the utilization of an animal model to evaluate the functional effect of Di-2-et h y lhexy 1 pht hala te (DEHP) accumulation, and (2) the development of an in vitro testing procedure that could be correlated with the animal s*udies. The rate of extraction of DEHP from polyvinyl chloride (?VC) is dependent upon both the temperature during storage and the lipid content of the medium. DEHP so obtained is in true solution, with particle sizes less than 0,22 micron. Tissue culture studies demonstrate that solubilize 1 DEHP in varying concentrations inhibits the growth an 5 ultimately kills human diploid fibroblasts. PVC ana siliconized glass transfused rhesus had abnormalities m liver histouathclogy and liver functions for up to 1 a months following cessation of transfusions. DEHP or silicon persisted in the tissues for up to iu months post-transfusion. Both the control rhesus and those transfuse'! with platelets processed in polyethylene containers were normal. DESCRIPTORS: `Plastics, `Toxicology, `Polyvinyl chloride. Blood, In vitro analysis, In vivo analysis. Tissue culture. Body fluids, 3lood plasma, Blood serum, Blood ceils, Plasticizers, Polymers, 31ood transfusion, Liver, Spleen, Tissues{3iology), Histology, Pathology, donkeys, Experimental data. Accumulation IDENTIFIERS: `Biomatenais, `Blood compatible materials, Animal models , `Phthalic acid/bis(etnylhexyl-ester), Histopathology, BioaccumulatiOt, NT 15 NIHHLI PB- 247 1 68/8ST NTIS Prices: PCS5.50/.1F 2.2 5 NJ CJ1 -fe O) JO 1, t* * , jL - Standard io r Occupational Exposure to vinyl Chlorile National Inst. U07 192) C56 74J3 FED; 19 7 5 1C p .ION I TO!: 1 ! See also P3-246 for 0 ecunatIona 1 Safety C6J, 06?, 57:;, 9d, 6dG 572. and Health, pock villa, U3C P.D 27 60 2 . 11. ( i\ 33 TRACT: The report includes: Background (events and t.oxicoioijira i :inds) of the standard; scope and application; definitions of terns; re :uiraments tor regulated areas; routine operations; reactor a r.c vessel entry; aair.tenar.ee and d^con t a min a ti on ; hygiene measures; signs; informa tier. ar.J training; environmental monitoring and record keeping; reports; medical surveillance. Despite the fact that animal experiments have shown no liver tumors at atmospheric concentrations of 50 ppm, the concept of an allowable wording level is rejected, Since there is measurable concentrations of vinyl chloride personnel should wear an air-supplied respirator because chemical cartnuge respirators do not afford adequate protection against vinyl chloride vapors. nsSCPIPTOPS: `Hazardous materials, `Industrial medicine, `Vinyl chloride. Toxicity, Criteria, Inspection, Standards, Recommend ations. Industrial nygiene. Industrial atmospheres, Chloronydrocarbons. Chlorine aliphatic compounds. Protection, Safety, acquirements. Evaluation, Carcinogens IDSNTIFT2F5: `Occupationa hazards. Air sampling, NTISHEWOSH Health Act of 1970, PS-246 591/03T NTI5 Prices: PCS 3 . 5Q/.1FS 2.2 5 v h- R&S 025464 m- 'of- yt B: # W:" M i l; * i`' i: i-. i;'`: S1' 1', e. e-*' Registry .^ofi/Toxic > Ef fects .o f chomi cal Substances. 1475 Edition National Inst, for Occupational Safety and Health, Rockville, AUTHOR:-Christensen, H. ., Luginbyhl, T. T., Carroll, 13 C56.73A3 , vFLD: 06T, 06J, 5 7 Y , 57U, 6HG * U S G R D R7 6 0 2 Ju.t 07 5 1 399p* PEPT NO: HIOSH-TSL-75 CONTRACT:,PHS-CDC-99-7U-92 MONITOR: 18'; Md. A33TRACT: * The 1975, Edition of the Registry of Toxic Effects of Chemical ''`Substances, formerly known as the-MIOSH Toxic Substances List, ''is ,` the fifth - Edition prepared in compliance with the requirements ! of the Occupational Safety and Health Act of 1970 (PL-91-596) . This Registry contains toxicity information on approximately 17,DOC unique chemical substances along with about 98)000 synonyms. Information is given cn route of entry, toxic dose ar.d toxic effects including an indication of axisting evidence of the substance'inay be carcinogen, mutagen, teratogen, etc. DESCRIPTORS: "Toxicity, "Chemical compounds, "Hazardous materials, Indexes(Documentation) , public health. Dosage, Industrial medicine,. Standards, ' Chemical properties, Exposure, Asbestos, Pesticides, Carcinogens, vvinyl chloride. Mutagens, Aquaticc animals. Toxicology -occupational Safety and Health Act of 1970, Maximum permissible exposure. Teratogens, "Occupational safety and health, NTISHEWOSH PE-296 557/3ST NTIS Prices: PC$41.75/BFS2.2 5 rtwip". ' `V;/ -- $ Hi t\i MB' . l: 'C ' thfc r rV.t, i \ * `.iv S3 jj - '* f'm'';.'v -:^ .:. ' , 1^;:--r,<ri*i.y* ^ -- ca 1 and Tox icologica 1. Aspects of Snoie produced During &-*'r\". ;...'.the.'j,Combustion-.>* of Polymeric Materials - <-i\ ;< V- ''rfii V( * i ' Utah Ur. iv., Salt Lake City. Flammability Research Cen tec. *N a t ion a 1 Science- Foundation, Washington, D.C. Research Applied to National Needs. ' . .Annual rept. 1 972-73 AUTHOR: Zin.orn, I. N. , D l r it y r i. W , Packnam, S. Petajan, J. H. C5384L3 FLD: C6I, C6P, 57Y, 57S, 71 USCRDR7524 I ' 2ji,,Sep 73 /160o REPT -NO: FZC/UU-12, UTEC-73-161 i; GRANT: NSF-GI-33650 a HON ITOR: NSF/RA/E-73-196 Vs .ABSTRACT: A study was undertaken at the Flammability Research Center of.:,the University of Utah to determine the physiological and toxicological affects of smoke. Four classes of materials were selected 7,for study: cellulosics, urethanes, polyvinyl chlorides, and Douglas fir. Smoke chambers and animal exposure chambers were s developed for the analysis of smoke and its components ana tne *1 observation , of effects of combustion products on aniaais. The effects of .combustion products on survival response in rats were measured, and toxicological studies of rats under exposure to smoke were made. The effects of y'combust ion ' on the eyes of the animals are tne subject of $ continuing experimentation. Small-scale laboratory fire experiments i are .being .correlated with full-scale fire tests conducted at the National , Bureau of Standards. Selected case histories of fire injuries are ./.being studied to determine the medical history of victims until 'recovery. -:,r , --V^1, ''''O DESCRI PTORS `Toxicology, `Combustion products," Flammability, Waterials,Ar." Smoke, Fumes, Physiological effects, Responsas, Experimental .., data. Laboratory animals, Rats, Polyvinyl chloride. Chemical-analysis, Urethanes, Injuries, Cellulose, Fir wood - -H, . -V, v - TDENT lEXERS': V NTISNSFRA i$-:' v' ': -P3-3244 '876/9ST NTlSPrices: PC 36.2 5/HF 52.2 5 3D (/) 0 IO 01 -t* o> CJ1 m .f hstz?* m ;v,'& 2v,' /' 5!$8ftV'.-:>#? lastic 3-2 Vic as Ha ving ;Con tact with Blood " t, ->AhV-.\`^'fe#>r`V'1 jit;v 'S''-'.. *,'. , ' "'> - \Salt.>' Lake '`'City. Dept, .-of Applied |l*r^#^n^s*.,'l?'?tional H*art and, Lung Inst., Bethesda, <!.- Pharmaceutical Lyman, Donald' J. , Soil, SrS'3 r.^nya:!i.^ swart A. X 03 ^.VFL'D: ,0 67, '.06 L ,`5 7 Y * , 95A*, 95C USGHDR7 5 23 s' - '1H . mW^-Wwi 'XifCm-TjaACT Y ;P;H S-7 3-2 9 C 3 m Ss:xjp'^fc' i:XhInitoe :X;i nyhl i -7 2 -6 ;** Sl^Vt* " "SjkValso' P3r23 3 7C1. David'3., '^^^VpoX/yy-inYl'w^hloride (PYC) ; and, more specifically, the comaonl) i^lVticizeeffi?; di- (2-ethvlhexvl) phthala te . (DEHP) . Selected fir 'X\> '"'i^'icatet^tha't (1) the acute1 and subacute LD50 of a metabolite o - (5,0 r.o-2--1`et hy'3- hex y 1) . . ph thalate) ,. given,' intravenously ylf-Tvy.,- v'A*'5' jw53V - /'>l ;, ,'"' 1'^.(/r'.anke. ri.to-r.ealiy1 . in .mice ;or rats is higJ hly* 1 toxic and irritant.1 (2) ae.jvMf;.*.--*.4mgL..'.Xv'.' 1 .r* " --f.AnnaaTy sis'iVo'f'. par tide size distribution of DEHP dispersed in fetal calf - - Jtr+,(Jj,,lPv, r'.T ilrS`>",\V.w.' ` S UU' W. ; i;.'`s^rum-iby^sonication'.mdica tes that :t he vast majority of particles are add;^.- , 1-|,S5 Vvt'nan, .'2:,.microns diameter. (3) DEHP appears to have some effect on r*T! T-'.'.Sin' i:;,''1'- 1 , eifferaosomes'V. in human leukocytes and human fetal lung cells in tissue Xc"u Vrur e..?...../...'..(.......)...' DEHP prolongs hexobarbital sleep. Phthalate-con taninat ed sheets, caused greater adhesion and aggregation of platelets than u when exposed to sheep blood in ex-vivo .chloride. if. 'y-XO C'' - -J;; "iioxicology, Lethal'dosage, Pathology, sue culture. Bioassay, XX.lit-jy.'f--XXsjniplles,yhecha meal .organs, . Plastics, Plasticizers, Body fluids. Blood, Laboratory Humans, Phthalates, Hedical 1 ... '*" Blood ''compatible materials, Bioma terials, Phtha*ic bisi(et hylhexyl-ester) , . NTIS MIHHLI NTtS Prices: PC35.25/HPS2.25 yiXfpy:r !# AA; jJ.. i - `f' ';`*V - A1 . .r: fr. a,- _ |i&;' Ai- fSTt<rJiV 1 ' JS^' ` ,,JmIsr.*., mi 7hr ?e 'Meek Intravenous Administration in the bog DI (2 2hih a 1 a t e Ethy Ihexyij Hazleton Labs. America, Ir.st., Bethesda, Md, W Inc., Vienna, Va. * Na tior.al Hean and Lung : Final rani. 9 Jul 7u-28 Feb 75 AUTHOR: Rutter, Henry A. Jr C5254F1 FLD: 06T, *57Y USG2DR7522 9 Apr 75 55p CONTRACT: NO 1-HD-2-2991 MONITOR: 13 Sponsored in part by National Heart and Lung Ir.st., Bethesda, Md. See also PB-224 37C, ABSTRACT: A repeated dose of approximately 0.50, 0.75, and 1.4 I -v mg/kg/day of di(2-ethylhexyl) phthalate in canine plasma was administered to beagles for 21 days. No consistent compound-related alterations were observed in animal behavior or hematological and clinical chemical parameters. Terminal body weights, organ weignts, and organ/body weight ratios were acceptable normal limits -and comparable to control values. Compound-related histomorphologic I alterations were not observed in dogs receiving various concentrations cf di (2-ethylhexyi) phthalate leached from pvc blood bags during storage. DESCRIPTORS: `Toxicity, `Phthalates, `Plasticizers, Dogs, 3ioassay, Laboratory "animals. Dosage, Medical equipment, Medical supplies, Tahles (Data) , Experimental data. Animal behavior. Histology, Morphology,.Polyvinyl chloride, Pathology IDENTIFIERS: Biomaterials, NTISNIHHLI PB-2UU 262/2ST NTIS Prices: PCS4,2 5/M F3 2.25 30 *> CO NJ CJi $ 4* 16 O) vj ,"insolent. Air Measurements of Vinyl Chloride in the Niagara Falls Area National Environmental Research Center, Research Triangle Parx, N.C. Chemistry and Physics Lab. Environmental lor.itoring series AUTHOR: C,ay, Bruce w. Jr, Noonan, Richard C, C5175A3 FLD: 13B, 07A, OfiF, 6 BA, 993, 57(J Yay'75 19p PERT.,NC: RPA/650/U-75/020 PROJECT: ZPA-ROAP-21AKC 0 N ITCH: 1 d USGEDS75z1 ABSTRACT: A 6-day survey was conducted in the Niagara Falls area to determine the concentration of vinyl chloride in the atmosphere. Samples were; obtained in a residential area adjacent to the chemical plants where vinyl chloride emissions were suspected, in areas around the plants, and in other areas of Niagara Falls. Tha highest concentration of vinyl chloride measured was 40 ppb tor a 5-hour integrated sample observed at a residential area two blocks east of a vinyl chloride polymerization plant. Grab samples taken downwind of cnami cal plants exhibited a hign of 2d ppb Samples taken from dcwntown Niagara Falls and upwind nortn of the chemical plants contained no detectable vinyl chloride. The areas surrounding the chemical plants, including the adjacent residential areas, are also affected by emissions into the atmosphere of chlorine and other halogenated compounds as exhibited by the deterioration or metal surfaces, particularly aluminum windows and doors. D"SCfi*?'0a3* Air oolluticn, 'Vinyl chloride, ^Chemical plants. New York," Angiosarcomas1, Chlorine organic compounds, Halohydrocarbons, Aluminum, Buildings, Corrosion, Sampling, Public health IDENTIFIERS: -Air quality, Niagara palls(New York), *.Air sampling, ' Air pollution effects(KateriaIs), Ai- effects(Humans), NTISEPAORD pollution pollution ? B- 24 3 6 9 5/4 ST NTIS Prices: PC 3 3.2 5/SF f2,2 5 5/ ,/: >. A r rime w o r k Speeches) y o.ntrol of ""oxic Subsr.ar.ces (A Compilation of Environmental Protection Substances. AUTHOR: Schweitzer, Glenn C51CUA1 ' FLD: ObT, Ob.), Apr 7 5 57 p REPT NO: r?A/`.i6C/U-75-0C4 .'IGNITOR: 19 Agency, E. oar,, 6 a A , Washington, D.c. odD, 97Y, 57IJ, 9 7 office of Toxic - U.SGRDR75 20 ABSTRACT: This collection of speeches it. large measure reflects the evolution of the interests, policies, and programs of the Office of Toxic Substances from April 197J to darch 1975. The speeches deal with questions that are of broad national concern: the identification of chemical hazards, the need for development of toxicological and other data on chemicals, the pending Toxic Substances Control Act, and need for regulation to control toxic chemicals. DESCRIPTORS: 'Public health, 'Toxicology, *Environmenta1 impacts, Industrial medicine, Environmental surveys, Government policies. National government, legislation, Economic impacts. Inorganic compounds. Organic compounds, vinyl chloride. Regulations, Decision making, Hazards IDENTIFIERS: 'Hazardous materials. Toxic Substances Control Act, NTISEPAOTS P0-24J 459/5ST NTIS Prices: PC34.2 5/N.F S2.2 5 R&S 025469 Evaluation of Vinyl Chloride Associated with Heat Sealing PVC Products yIVironmental Health Lab Hcclellan AF3 Calif (407609) Fir a! rent UTh'OH: Smith, 3illy S. , 3urr.ett, Ronald D. , Diamond, Philip, Greathouse, Jacx E. C4 7u5? 3 FLD: 6J, 57U USGRDP.7915 Sue 7 4 70p iZPT HO: SHL-7417 PROJECT: HAF-351 rtC'ilTOR: 19 R&S 025470 polyvinyl chloride (PVC) sheets or film. The potential for VC exposure was evaluated by analyzing the PVC materials for entrained or encapsulated VC and by analyzing air samples collected during the meat wrapping and welding operations for VC. The results of all analyses are shown. The potential for exposure to vinyl chloride monomer at the 0.1 ppm level was not found to exist in either of the two operations studied. No vinyl chloride monomer was detected in the PVC materials. DESCRIPTORS: Industrial hygiene Exposure(?hysiology) , Polyvinyl chloride, process mg Packaging, Weldmg Gas analysis, Heat, Pood IDENTIFIERS: Vinyl chloride. Indoor air pollution, Gas sampling. Air pollution standards, NTISDODA? AD-A0C9 997/8ST NTIS Prices: ?C$4. 25/.1FS2. 25 '"^`^^'-'^'-V""l-'""1VS&>}'w81, "f& ,; y] L-"- r'-. ; ffrf'h -*v V ^ . ' '^ > ,si.* ; U ,,,?:e l:i;r,a ry ^'Assessment of the Environmental Vinyl Chloride and Polyvinyl Chloride Problems Assoc.aiv't with Environmental Protection Agency, Washington, D.C. office or Toxic Substances. '&' * ^" ,Vr;Interim reptV v C4385E4 F.LD: 133, 68(1* 9S33DR7509 Sep 74 106p* SEPT NO: EPA/560/4-74-001 ; ION I TO H: 13 report on' .the Activities and Findings of the Vinyl Chloride Tasx Force.1 ABSTRACT: The report summarizes the activities and findings of a task force to assess the character and extent of the problems associated with the production, distribution, use, and disposal'ot vinyl cnloride ar.d polyvinyl chloride. The first Section discusses the nature and magnitude off;' problems. The second discusses previous and planned activities '(within the Federal Government of particular significance ar.d the cole of industry. The report concludes with some specific recommen dat ions. '* DESCRIPTORS: ' Air pollution, Water pollution, chloride,. *?olyvinyl chloride, Surveys, Problem Ecology, Tests, Industrial relations ^Toxicity, solving. Vmyl Health, IDENTIFIERS: Air pollution abatement, NTI5EPA0TS P3-239 1 10/0 ST NTIS Prices: PC $ 5.25/MFS2.25 X Q CO J3 cn -fe M t ' .......... 6D 'xperime ntal Drit.ii Serving an a Basis ror Seourate Pe r.m ssib Le o.ncen `.rations of Di but1/ i ph tha la te .itional Institutes of Health, 'ini t. En v iro naent al Protection Agency, rrar.sla tier. Services section. v;?HOS: Spasovski, r.incho .'joasci' FLO: 0 6 J, 06T IJ5.0R03750 .,"il 7 3 8o .KPT NO: 'JIil-73-370C tOSITOK: SPA-TP-29-74 Trans. or Xhigiena, 3 pidemiologiya i pjd-44 19fc!l, Bethesda, .id. Translation Research Triangle Par*, N.c. hikrobioiogiya (Bulgaria) v7 ;dSTRACT: Pased on experiments using animals subjected to single and multiple innalatory, oral ar.J skincoating dosages, and which are supported by mathematical and analogical methods, the separate permissible standard for concentrations of industrial dibutylphthalate heated above 140C is 0.C01 milligrams per liter of atmosphere. The -oxicity of dibutylphthalate depends upon the modality of its introduction to the organism, host toxic are its fumes heated above i-iOC which. penetrate and consume the lungs. The substance is weaxly toxic in oral application. It does not possess skin absorptive caoaoility. Dibutylphthalate possesses a highly cumulative effect in inhalation and ingestion. The cumulative coefficient falls just short of tone, which explains the hypersensitivity associated with it. DESCRIPTORS: *Phtha 1lates , 'Toxicology, 'Plastics, 'Industrial medicine, Industrial atmospheres. Polyvinyl chloride, 3ulgana, Translations, Lung, Laboratory animals, Experimental data. Exposure, Permissible dosage, fumes IDEHTIFIIRS: Phthallic acid/(dibutyl-ester) , Indoor air pollution, liTISEPAISD, *;iTIS:!IH ? 3- 237 886-T/S7 NTIS prices: PCJ3. 2 5/-.FS2. 25 The Effect of Dibutyl- md Dioctylohthalatos on Rats with Oral Feedir. j dur ir. } Prolonged Testing. Part 'l. Application and Tox icoi o; ic 11 Properties or Dibutyl- and Diocty1-Phthbates f [ | National Institutes of Health, Dethesda,- .id. Translation 'Jr. i t. * Z n viro n me nt a 1 Protection Agency, Research Triangbe Par*, N.C. Translation Services Section. A O' T H C ?: Piekacz, Hanna C39 94L4 F I. D: 06T USGRDR7503 197 4 19 p PEPT :iG: NIH-73-374C ICNITOR: HP A -TH- i 9- 7 4 Trar.s. of Poczniki Panstwowego Zakiada Higieny (Poland) v22 pbb-DI 197 1. * ABSTRACT: The use of dibutyl- and diocty1-phthalates is discussed a propos of legislation in various countries, as well as tneir toxicological properties. This study serves as an introduction to research on hyperacute and extended toxicity of both phthalates. DESCRIPTORS: *Phthalates, "Toxicology, Chemicals, Polyvinyl chloride, Manufacturing, Poland, Translations SI IDENTIFIERS: Phthalic ac id/ (d ioc t y 1-c? s te r) , Phthalic acid/(d ibut yl-aster), NTISSPAISD, NTI3NIH FB-237 d d 5- T/ST NTIS Price: PCS 3 . 2 5/MF 52.25 ! - - -..........r-- R&S 025474 ']au:d tijr. o: :>:-2--thy lhexy i P^thsLi^ ( D E H P) tele*. Cor,of- r.* : ic.es, a ::il PL l te le - - Poor Plasma in (inol's Blood, ivii 2:1 oo I Research "7 !i0.1: Cor.tr *_- r a s , T !' 11 : 1 FLD: f.L . ,;e? 7 1 1 5p 'USCT: 41304 1 . 02 , Ad X ; 1 ? 0 4 1,0 2.0 1 ^ ^ * "'A ^ ^ La n Ch elsea "ass J. , S h e i b 13 y , ?. 'J3SP.D37424 ( J87481) il , Valeri, C. P. < -:vioior* of report jure2 JO 1.ir 7 J , See also AD-788 bbu. .a n 11 i t y: Pub. in Trar.j :usion , v 14 r 1 pju-46 Jan/Feb 74. . biT3,\ L . The concentration or the plasticizer, di-2-ethyIhexyl 1 .is :ia 1 a* e (DSH?) . in "he plasma was measured after storage of the wh 3 1*5 bl QO'i in polyvinyl chloride p lastic bags at 4C for- up to 38 days .i eit n * r AC D or CPS. The plasma fr on ACD-stored whole blood contained D E HP than that from CPD-stor ed whole blood. The continuous-flow f U ear ion washing procedures removed about 98 per cent of the i r'.i P 0 31 A CD whole blood stored for JJ days at uc. DEHP was assayed plateiet-ncu plasma, plate let-poor plasma, supernatant of tne 1 4 t -5 I t; " concentrate, washed pla telets, and washed red blood cells r 3 par * ) troui CPD whole blood, Very little- DEHP was found in the i:; h* i red blood cells ml platele ts, a small amount was found m tne i` 1 ^ * o ^ * t -poor plasma, Urel concentrate. and a lar ge amount m the supernatant of the A greater amount of DEHP accumulated in tne -1 a t ^ 1 e * concentrates that were st ored at 22C than m those stored at ^ C i n i. platelet concentrates *rorr. CPD whole blood were stored at 22C r o: 7 hours, the amount of DIM? was about four times that observed * f. er 4 C storage cor the same ieng h or time. (Author) DESCRIPTORS: * 31 o o d , *?hth alat<=-s , `plasticizers, `Polyvinyl chloride. Plastics, Dags, Dlood plasma. Blood platelets. Accumulation, Blood banns, Storage, Blood transfusion. Toxicity .ENT I FI SF.S : Phtnalic au id/l: is (eth y 1 hexy 1-ester) , NTISDODS ,1-788 2 53/SSL Price: Reprint f ?! 63 ` -* ; M #3 ,. , . , .4 , ' \ -4 , V^., av. Jfci , \ 'f' < .;,v' v ,! . v :v#V? > T1* VWf'ft* 'ut'TfSvH^pr* r 2, t . ' - * o,+'fs'*'n: */.'i f?W,* `wi'f1 ''Aw?*' /A1 R&S 0 2 5 4 7 5 Toxicology of Plastic Devices Havir.-j Contact with Bleed Children's Hospital Medical Center, Boston, Mass. Annual rept. San 73-18 Jun 74 AUTHOR: Kevy, Eherwin V., 3utton, 03294111 FLD: 6T, hL, 577, 9 5A, 2l|jun 74 52p* MONITOR : hi;!/NHL I-7 2-29 6 9 ',,V'< Lawrence , Jacobson, 9 5C USr,HDH74iq May 3. ABSTRACT: Continued studies are presented that evaluate tne possible tbj[x icologica 1 effect of Dr-2-e th y Ihe x yl phthalate (DEHP) extracted fr.pn poly-vir.yi chloride (?VC) plastic by blood and biologic fluids. Specific studies are outlined in four areas: The preparation or an antibody to phthalate in rahbits for use in mmuno- 1 uorescent studies and 'a radioimmunoassay for detection of phthalate; bi-weekly platelet transfusions after storage for 48 hours at u and 22c m ?vc, polyethylene and siliconized glass is a natural and clinically oriented method of phthalate administration; evaluation of these animals for- hepatic, splenic and pulmonary functions by means or nuclear medicine techniques, liver function tests and compartmentai BSP "analysis; tissue analysis of tranfused and non-transfused patients for DEHP; and quantitative analysis of liver tissue for DEHP of multi-transfused Rhesus monkeys. DESCRIPTORS:' `Plastics, Tcxicoiocy, chloride, Blood, Tissue culture, Medical Experimental data. Antibodies, Phtniates, animals. Blood transfusion : Piasticizers, Polyvin y1 supplies, Mechanical organ Bioassay, Humar.s, Laboratory IDENTIFIERS: `Blood acid/bis (ethylhexyl-ester) compatible materials. Biomaterials, NTISHEWHLI Phtaalic PD - 233 P.57/2 NTI3 Prices: PC35.75/nFSl . 45 7*C\- 64 .ixicolayy of Plastic Devices !! .'i v i .19 Cor. act with cl cod i.\h '.T.i V. , salt Like City, coll, o: Pharmacy. T.*.-irin rept. 2U Aug 7 2-1 hay 7u -'CliOH: Lyman, Donald J. , .-.oil, David b. , .)2b3I1 rLD: hT, oL, 5 7 f * , )bA, u$c ";y 7 u 2 J > p 'SANT: P MS- 7 3-290 4 r;:TD!<; NI H/HilLI -7.i-2 JO11-!! ivinvard, Ewart *J ?i2D F7 4 1') A ';)iT?.\CT: The project is primarily concerned with toxrcolog ical valuation of polyvinyl chloride and, sore specifically, the commonly plasticizer, di (2-ethyihexyi) phtnalate (DEHP). Evaluations are :3v. c an tr ate J on . long rang?, subtle toxicity potential, although basic .cute and subacute studies are also utilized. Plastic composition todies, acute toxicity studies, tissue culture studies, subacute oxicity studies, metabolite identification, teratogenic studies, neurologic studies, larger animal studies, analyses of human blood -xposed to plastics during hospital procedures, and possible ;*. atisticai analysis or human patients following extensive exposure of nfocd to plastics are included. Selected findings indicate that: Plastic components which contain DEHP as a plasticizer are toxic to L-929 cells in tissue culture; DhHP appears to prevent implantation of fertilized ova in rats and mice; DEHP affects rate and amplitude of contractions in isolated rat hearts; DEHP is hydrolyzed m vitro by liver microsones and mitochondria but not by cytosol. '2JCRI PTOP.S: *.?olyvmyl chloride, Plasticizers, Diced, nedicai supplies, organs. Experimental data, Phthaiates, Hioassay. Neurology Plastics, 'Toxicology, Tissue culture, mechanical Laboratory animals. Humans, IDENTIFIERS: * 3lood compatible materials, tcid/bis (ethylhexyl-oster) , 3iomateriaU, NTISHE'.HH 'Pathaiic 13-233 7D1/2 h'TIS Prices: ?Ci5 . 75/".Fo 1 . us tii R&S 025476 FsSt#iakiit. Pf#iP! it;a' r^j; . i,. r.r..':-: I 1lfi**&**!^3J. ft ! ,1 E^ji r . .Fr ,- Dynamics'" of Hyqanic .'orlcir.y Conditions and Occupational Disease Inci ier.ce .among workers in Suspension Polyvinyl Chloride Production ever a Number or Years ..National' Institutes of Health, Bethesda, Nd. Translation AUTHOR: Filatova, V, S. , An tonyuzherko, V, A. C3214A2 FLD: 6.J, ST U5G?.DR7u1d Jul 7 U 7p PFPT NO: NIH-7U-J52C ' NCHITOR: ,i0 . Trans. of Gigiena Truda i Professionalnye Zabolevamya ,;p32-3u 1971. Unit. (USSR) v15 ru , ABSTRACT: The occupational disease incidence in workers resulting from -vinyl chloride air pollution was studied over a period of 17 years T (19 53- 1969) . Although industrial conditions have improved, there still .occurs new cases of cnronic occupational poisoning. Various clinical g.manirestations of chronic vinyl chloride poisoninq, as a function of ^'environmental air pollution have been established. A series of v.ittea sures designed to improve air quality in worn areas is suggested. -DESCRIPTORS: `Industrial hygiene, `Occupational diseases, `Industrial .atmospheres, `Polyvinyl chloride, Air pollution, Toxicitv, Toxic -diseases, USSR, Translations IDENTIFIERS: Air quality, NTISNIH, NTISH2WIHL 1 ?B- 233 6 1 U-T NT IS Prices: ?CiU . 00/.1F31 . 45 R&S 025477 Jfc-v . fHt?*''r'*'r% i',t ,.\i\* ."cN. A.' /, - 'S'-.; 1 ,:RS.i^v: [fesi ee Health Hazard evaluation/?oxicity Determination. John Morrell Comoany, Sioux Falls, South Dakota ^397^^j Inst" f0!r Occupational Safety and Health, Cincinnati, Ohio. Final rept. Oct 72-Jan 73 AUTHOR: Polaxoff, Phillip l., 7andervort, Robert C30dUE2 FLD: 6J, 67, 577, 94D, 68G Oct 7 3 15p L'SGRDR7416 KEPT NO: NIO SK-TH-039-74, HHE-71-29-39 ,10:1170 a: IB \ ABSTRACT: In response to a request received from a representative of employees, the National Institute for Occupational Safety and Health (NIOSH) conducted a health hazard survey to evaluate exposure to thermal decomposition products of polyvinyl chloride neat packaging film at John Morrell Company, Sioux Falls, South Dakota. Based on medical evidence compiled during a limited study of meat wrapping employees it was determined that air contaminants generated by the thermal cutting of polyvinyl chloride packaging films in conjunction with the wrapping of meat are potentially toxic to some meat wrapping employees. Symptoms range from aiild eye, nose and throat irritation to mors serious respiratory problems for meat wrappers wno have an underlying predisposition tc respiratory difficulties. Recommendations have been suggested to management regarding preemployment examinations and work practices. DESCRIPTORS: "Hazardous materials, "Industrial medicine, "Polyvinyl chloride, Toxicity, Criteria, Inspection, Standards, Recommendations, Industrial hygiene. Packaging, Pyrolysis, Respiratory infections IDENTIFIERS: "Occupational Safety and Health Act of 1970, Packaging materials, ' "Meat packing industry, "Toxic hazards. Air pollution effects(Humans), NTISNIOSH PB-232 578/5 NTIS Prices: ?C5U,00/MFSI.45 3J ft </> oro ui -4 00 -;i-^^-:!|j"^^^;/^ :.--sf/ '$ v.:^v-':'`.;,v';'" .r "`r",J> .`' " '' ' JV i I Health Hazard Evaluation/Toxicity Determination. Sea ttle , Washington National Inst. (Jyu 7b6) for occupational Safety and Health, Cincinnati, Ohio, Final rapt. Aug 72-dan 7 3 AUTHOR: Polakofr, Phillip L., Vandervort, Hobart C2705IU FLO: 60, 570, S7Y, -340, 68G USG8DH74 1 1 Sep 73 23p RE2T NO: NIOSH-7F.-070-74 , HH2-72-53-7C MONITOR: 18 Also includes ?,ept. nos, HHE-72- 54-7 1 thru HHE-72-58-75. A3STRACT: in rsponse to a received from a representative ot employees the National Institute for Occupational Safety and Health (NIQSH) conducted a health hazard survey to evaluate exposure to thermal decomposition products a polyvinyl chloride (PVC) meat packaging film at six retail grocery companies in the Seattle, Washington area. Based on medical . evidence compiled during this limited study of meat wrapping employees it was determined that air contaminants generated by the thermal cutting cf polyvinyl chloride packaging films m conjunction with the wrapping of meat are potentially toxic to meat wrapping employees. Symptoms range from mild eye, nose and throat irritation to more serious respiratory problems for meat wrappers who have an underlying predisposition to respiratory difficulties. Recommendations have been suggested to management regarding pre-employment examinations and work practices. DESCRIPTORS: "Hazardous materials, "Industrial medicine, "Polyvinyl chloride. Toxicity, Criteria, Inspection, Standards, Recommendations, Industrial hygiene. Pyrolysis, Packaging, Hazards, Respiratory diseases. Air pollution IDENTIFIERS: "Occupational Safety and Health Act of 1970, MIOSH P3-229 709/1 NTIS Prices: PC34.2 5/MFS1.45 R&S 025480 Coal Mine Combustion Produces: I dent if Leat10n.and Analysis Ult rasysterns , Inc., Irvine, Calif. [407 617) Annual rapt. FY 1972-73 AUTHOR: Paciorek, K. l. , Kratrer, C2314G2 ?LD: 7D, 213, dl, ;JSG RDR7406 Aug 73 160p REPT NO: SN-3220/A1 CONTRACT: KC 1.33004 MONITOR: EuMines-Or?,-0-7 4 R. H., Kaufman, J. , Nakahara, J. 111, 11L, 4 8 , 710, 99F, dIA, H. 713 AOS TF. ACT: The toxic products formed during thermal oxidative degradation of neoprene and polyvinyl chloride compositions, urethane foams . and various untreated and treated woods were determined quantitatively on a g/g basic. Quiescent and dynamic decomposition conditions were employed. Analyses were performed using high vacuum separations, gas chromatography, mass spectrometry, infrared spectroscoov, and wet chemical methods. The mam toxic species found were among'others CO, HC1, HCN, 302, anhydride, aniline, and furfural. Thermcgraviaetric analyses were performed on all the compositions, and the data were correlated to available formulating information a.id product formation. IDENTIFIERS: Brt P3-226 944/7 NTIS Prices: PCS 11.CC/hFS1.4b 6S let'* f,,a p'.i-i/V' V' ^'- :,r-'^.'............ "' *' ; ir i .X l*ff' r ij A Toxicological Evaluation o Certain tlepa cl r.-Qua ternar y Aamor.i::; Complexes ' Sat tel 1 5-. CO lu a bus Labs., Ohio. (UJ7 08 0} Annual rept. 1 Oct 72-JO Nov 7J AUTHOR: Grode, G. A., Crowley, J. ?., Fa lb, R. 0., Leinnger , H. I. C2313K1 1 f LD: 6T, 6L, 7C, 57'/*, 95A*, 99C USGRDR7U06 26 Dec 7 a 3 3p* CONTRACT: PHS-7 J-2910 .ION I TOR: 18 ABSTRACT: Physical and chemical characterizations show that tne heparin-quaternary ammonium salt complexes can oe reproducing prepared from a given lot of a quaternary ammonium salt. Local toxicity studies also indicate that both the tndodecyl methyl ammonium chloride-heparin and tricapryl methyl ammonium chloride-heparin complexes elicit qualitatively similar responses, while quantitatively, the TCM AC-heparin complex produced a locally more severe response. Single-dose toxicity studies of the heparin complexes, carried out in mice, show that the TDM AC-heparin complex is the more toxic with an LDSO value of 3.3 mg/kg, as compared to an LDbO of 195 mg/kg for the TD MAC-hepar in com piex. This toxicity gradient is perhaps the reflect ion of increasing solubility of the complexes in the biological medium with the (C9) i capryl-based heparin complex (TCMAC-'neparin) being the most soluble. Experimental evidence indicates that the toxicity of TDMAC-heparm treated poly {vinyl chloride) devices is very low. DESCRIPTORS: 'Heparin, 'Mechanical organs, 'Mechanical hearts, Sur race properties. Toxicology, 31ood plasma. Plastic coatings, Ammoniurn compounds, Polyvinyl chloride. In vitro analysis,. Annttiiccooaagulants, Surface chemistry IIDDEENNTTIIFFIIEERPS: 'Quaternary ammonium salts, 'Blood compatible material ^ f Aaaoniim/methyl- tridodec yl, A maonium/meth y 1-tridecar.o yi, NHLI P3-226 886/0 NTIS Prices: PCS 3.2 5/.MP31 . US nJ 70 \'*V ,*1`, . '*$),/. . i'i / ';!'* . ,/ . . . M Toxicology of Plastic: Devices Having Contact with Blood -*:, *> Utah Uni v./'salt lake city. (326 900) Interim rept . for 24 Aug 72-15 Sep 73 AUTHOR: Petersen, Hooert V., Lyman, David J,, soil, David 13., 5*mard, Ewart A. C19C1C4 FLO: 67, 6L, 57Y*, 95;,*, 95C USGBDP. 7324 Sep 7.3 11 7p* CON TRACT: NTH-NHLI-73-2908-2 .1CNIT0R: NIH/NHLI-72-6 ABSTRACT: The project is primarily concerned with toxicological evaluation of polyvinyl chloride and, more specifically, the commonly used plasticizer, di(2-ethyIhexyl) phthalate (DEHP). The project is divided into twelve tasks including an organizational phase. Plastic composition studies, acute toxicity studies, tissue culture studies, subacute toxicity studies, metabolite identification, teratogenic studies, neurologic studies, larger animal studies, analyses of human blood exposed to plastics during hospital procedures, and possible statistical, analysis of human patients following extensive exposure of blood to _ plastics. Selected findings indicate that: DEHP is poorly absorbed from i,p. = intraper itonea1 administration of massive Joses; the 30-day subacute i.v. * intravenous LD5C of DEHP in mouse serum is 355 mg/kg in mice; DEHP accumulates in lungs of dogs for at least 2 weeks during daily i.v. = intravenous administration; an efficient method for analyzing DEHP by gas chromatography utilizing an internal standard has been developed; and some components of renal dialysis and cardiac bypass units are toxic to 1929 cells by tissue culture methods. Portions of this document are not fully legible. DESCRIPTORS: ('Plastics, *3lood), (`Toxicology, Plastics), ( Plasticizers, Toxicology), Medical supplies, Poiyvinyl chloride. Addition resins, Elastomers, Thermoplastic resins. Tissue culture, Hedical equipment, mechanical organs. Experimental data, Phthalates, 3ioassay, Humans, laboratory animals IDENTIFIERS: Phthalic acidbis(ethylhexyl-ester), materials, *Dlood compatible materials, NHlI Biocompatiale P3-224 558/7 NTIS Prices: PCSu.25/MFS1.45 R&S 025482 j1 ''ft '& V:f;!fr' *. '{* Bt|i; "- *>-- *7-"''*-* :'--------- J" --------- y-- ' l" ' ,'. ,''' ` ' '; 1' &' ' Incineration of Plastics Four.! :r. municipal Wastes Syracuse Univ, Pesea rch .Cor p. , (319 750) Final rapt. AUTHOR: Heimburg, S. W., Colella, A, R, , Jon^s, D., Rausch, J. H , , !dc::.ia, t, C17 2511 FID: 1.13, 65C", 68 A USORDR7322 Sep 71 216 p * GRANT: EP-0G30U KON I TO3 : 2PA-6 70/2- 71-097 ABSTRACT: The purpose of this project was to determine the coonustion efficiency of plastics when burned m several types of laboratory incinerators. These laboratory units were designed to simulate the primary flame zones of municipal incinerators. The parameters of efficiency considered were: Percent of material consumed, the chemical 'cleanliness* of the gaseous effluent, the rate of production of flyash, and the more obvious environmental effects of the gaseous effluent, flyash, and residue-ash. Several pure resins were burned individually in several laboratory incinerators. Also, several mixtures of plastics and a garbage recipe were burned. Results are presented here from analyses cf the effluent along with the effects of each effluent on rats and plants for 1- to 3-hour exposures. DESCRIPTORS: ("Plastics, "Combustion), ("Solid waste disposal, Plastics), ("Incinerators, Plastics), Garbage, Fly ash, Air pollution. Combustion products. Polyethylene, Polystyrene, Polyvinyl chloride, Acrylonitrile copolymers. Polypropylene, Polycarbonate resins. Polyurethane resins, Urea formaldehyde resins, Kelamir.es, Toxicology, Rats, ?lar.ts (9otany) IDENTIFIERS: NEEC PE-223 6 51/1 NT IS Prices: ?CI5. 7S/P.F3 1 , U5 w* Coaj Nine'Combustion Products, Identification ar.d Analysis !Jlt ras ystens , Inc., Irvine, Calif. (UC7 617) f-Fir.ul rept'.' d Jul 71-7 Jui.72 .AUTHOR: Pa'cior ek, K. L. , Kratzsr, CC3H5E2 ' ` F.LD: 111, 7C, SI, 710, Jul 72 16 5 p * CON 7? ACT : H0122CC9 KONITOE: Eudines-OFR-1-73 E. . , Kaufman, 7 1 H, 5 7 H, oUI J. :JSG?.DH7305 ABSTRACT:- Little data`is available on oxidative deg'rative behavior of materials used in coal mines under truly dynamic conditions approximating the mine environment. However, because of the possible danger involved with the formation of toxic gases, the authors studied the deconposition of various materials. Tests were performed on: Polyvinyl chloride-containing materials; Neoprene compositions; Rigid foams (urethanes, isocyanates); rtiscellaneous materials (including jute, fiber glass and polyethylene) using a stagnation burner arrangement. it was found that the chlorine-containing materials evolved hydrogen chloride very readily, its rate of evolution being strongly temperature dependent. The fluorocarbon 'propellant and C02 were the main products found on decomposition of the foams, whereas among other products jute compositions liberated methyl chloride. The analyses were performed using mass spectrometry and infrared spectroscopy. A review of the combustion products of various polymers is also included. CE5CEIPTOES : (*Combusticn products, " Polymers), ("Coal mines, "Fire safety), ' ("Polyvinyl chloride. Combustion products), ("Chloroprane resins. Combustion products), ("Cellular plastics. Combustion products )', (*Jute, Combustion products), ("Polyurethane, Combustion products). Glass fibers. Polyethylene, Smoke, Gas analysis. Hazardous materials. Infrared spectroscopy, Mass spectroscopy, Decomposition, Reviews, Cellulose, Polyamide resins, Polyester resins, Epoxy resins. Toxicology, Corrosive gases IDENTIFIERS; "nine safety P3-214 12U/0 NTIS Prices: PC56.00/HF$0.9S .: W, fat, ,| :, , ('Ti r.Vf '% >. -/' '" * r^i'f*k^rrr^Vv;^:'r*'-- -,i . . Nv.ChemicaiTanJ ?hysical;iproperties and Thermal Decomposition ,^Cer tain'iJNatural Products and Syetne :re Materials ^* ^Environmental Health Lab Kelly APS Tex (300925) *1 Products of >; - : .jjr.echnica l'-rept . ^AUTHOR: -"eivia, w.ilt=r' w ,i"CC0'72I2 V KLD: 111, 115 7 2.,,-, 17C p* v5;pt ::oVr' :::.'(K) -72-1 u ^PRO J2C?: EHL-7 G - 7 ..MONITOR:-.; 13 . ,1 710, 7' 71-, ?,c 0303037302 APS TR AC7: A limited review of the literature including the early history and current data on deaths, injuries and costs due to the combustion and pyrolysis of resins, plastics and natural materials is provided. There is a limited discussion of the chemistry and physical properties of plastics. Applications of these materials in wearing apparel;,' construction trades, the aircraft industry, and others are discussed. Experimental data on the pyrolysis products of five synthetic and natural fiber carpets are presented. An extensive collection of tables from a number cr sources give data on the trade name, .type of plastic and manufacturer, physical and chemical properties, decomposition products, and other information. (Author) f^;- m I `i.'-4CV* > fc*V`-v | j fi* Carbon monoxide .IDENTIFIERS: Fire safety, *Carpets, Hyd rogeiib chloride, Hydrogen cyanide ^Flammability testing, Smone, AD-751 ,399 NTIS Prices: PC33.OQ/flFSO.95 ? mil !` '>l $ S'1 ^^T.ieA^' - \ ftf?." ,/fjVf 1 ` `vT* $**- ` <"r 1, i'r . ' 't-1#; `'`a'^9rials-'4*t3asec ! o r. V Polyvinylchloride for Packaging Food products Kg^*/,;/:^;:;{^a*;eria ly^#,na.' Osnr ove -`Pol ivmilkhlorida Ilya Upakovki Pishchary nh ...,J^>-' ; ?qduktuv> -. fv-- itl Arm y-\, Po rei?gn v'Scio nee aand Technology Center Charlottesville {? 038 300) ;;, ,' y ' y, a =; "' AUTHOR:'*Chants va, A . 3., Chernovskaya, S. ?., Ovcni nmicov ; ^`:r-;V?yv.? ' **:* 'y.". ` Alu2.73J2u2l3.7*.r1.e.`-?:1.rO/l: 11;, 13D, 52D, 710 E14EPTIni.'JO7:1" FS T1C1V--HT-23-8aG-71 USGEDR7119 Yu. jTrans. ' f romyp,1 asticheskie Sassy' (USSR) r.6 1970. va V. ( J vV' v; ABSTRACT: \ The physical, mechar.ica 1 and toxic properties of various types of:','polyvinyl chloride films suitable for use as food wrapping materials are presented. (Author) DESCRIPTORS:. ("Polyvinyl chloride, "Packing materials), ("Food, Packing materia Is), Films, Mechanical properties. Toxicity, Additives, Thermal-stability, Viscosity, Tensile properties, USSR IDENTIFIERS: "Food packaging, "Polymeric films. Translations AD-7 2a 150 NTI3 Prices: PC33.C0 MF3C.95 30 P 0) o cNn> b oo "si ` J,K,' v v*f.: /4 ' `VfVi Vf!  c* ' :r.;-y ;;,v: O'! THE vUESTIOH OF IMPROVING SOME POLYVINYL CHLORIDE PO L Y .**. EP.3 AND A METRO!; OF I-jPROVING THEIR TOXICITY lir Force .'Systems Command, 'rfnqnt- Pat tensor. Ai'B, Ohio. Technology Div, AUTHOR:' Gorban, G. M, FI. D: 1 1G 3TARC7CU Apr 5 4 lip FETT NO: AD-Sd0924, FTP-HT-23-1464-67 T r i r. - Trans I. Into English From Kosaich. 3iol. ted. (USSR), l'J-,7 p 47-51 Foreign v. 1, No. T IS '.y1 T ?TOF3: "Electrical properties, "Plastic tapes, "Polyvinyl chloride, "Ureas, Degassing, Electrical insulation. Nitrogen compounds .h-203a2 c.-STi Prices: PCS3.00 mfso.95 ABSTRACT: A method is developed for improving the polyvinyl chloride capes for the purpose of decreasing cl eir gas emanation. The overall gas emission of organic -mbstmiees from the improved specimens of polyvmvl chloride tapes as a result of the treatment with 5(/ urea solution is reduced by a factor of 2-1 /2. The improved polyvinyl chloride rapes give off volatile chemical substances in small concentrations, which with long duration of their action on the organism cause onlv a weaU biilogicul effect. As a result of the treatment with a solution of urea there is an ;mprovcmenc in the electrical insulation properties of [he polyvinyl chloride tapes serving the purpose for which rhe materials are intended without change in their strength characteristics. 77 J' : . 4. -:C ~ ;L , :^^'1/ it THE XFFLCTS a :;t i co a:; UL.w DER IVAT IV F.3 C? STO.U'JZ CONDITIONS 0? P L AS TIC 3L0U0 CONTAIN EPS ON THE (ACC) AMD THE PRES "RV ATTOM OF V HOLE bLOOD AMD ITS Texas (Jr. iv., Austin Drug plastic !i*sea:ch and Toxicology Lab. Terminal rept. AUTHOR: Guess, Wallace L. 5342,12 FID: 6L, 6T, 1 3D ! 96 8 4ip* CONTRACT: PH-U3-68-97 USGP.DF.bH09 ABSTRACT: On the basis of this study, it vas concluded that taece is clear evidence of a toxicity potential from some PVC blood bags currently available, There is insufficient evidence at the present time to evaluate the effects o; storage conditions beyond a one year period, but the stuly indicated no drastic alterations due to the one year storage period at temperatures up to 50 degrees C. (Author) DESCRIPTORS: (*Blood, Polyvinyl chloride. Storage), (*Bags(Containers) , Blood), ( Toxicity), Plastics, Bags (Containers) , Anticoagulants, preservation. Mice, Rabbits, Chromatographic analysis. Temperature, Pathology PB-182 732 CFSTT Prices: fCSb.QC M7S0.95 * i i 33 </> 0 ro 01 4* 00 <0 M