Document B5D0vYB3aEro6GJjeqzZG4jV8

Occupational exposure * RENATE D. KIMBROUGH Toxicology Branch, Center for Disease Control, De/mruncru of Health ant! Human Services, Public Health Servile, Atlanta, GA JOJJJ, U .S .A . P a $2, Review o f the available literature sucfests a clinical syndrome that is produced by the halofenated biphenyls, naphthalenes, dibenzodioxins and dibenzofunms. TAHU- 9CI Syni|U'iii\ and ,il|'ii< repHied after oceupmloual e.vjiOMirf. Sy Hem l.rv lo n Chem ical. r~--............ -- Reference-1 ------ ( O n erili blnm khoi rye*. l.nsluule, hcndndie. abdom inal polii, lin p n tiik Y . Mvlylil In**, iitioiiuiia, iili'iw k i, d kiurb mice In nido d ilitrin nicd nnpliihpJeik** trvhnlenl ikrtilnchlom phcim l 2.5,7,N -leirnchloriklibcn/iKllo\lii ddorhm tcd biphenyl* (*xkHl n m l l 'o tv k y , 19-15 1hunter nm l Hauer. 1*1y | ; U e lir M n n . 1959 J it ii'c k ei u l.. 197j Jo n e* nm l A ld e n . 1956 Skin* l iver c lilo n ic o c . p u riiio . nenie vello- atrop hy, hepatocellular n cero *k , miltl n tiro d *. fatly chm ipe. abnorm al liver function, porphyria euuinen iarda 2 J.7 > .T C *D I) eldoriiinled biphenyl* ddoriim ied rmphihnlenc* le d i: p o i l a d i lo n plurimi oilier le d i. ddorinnjcd phcnnk vlilorlim ied im pililialene* d o ra * . pemn-, beva-) 2 .J.7 .*-T C n i) le d i. pcnindiloruplicnol IKilycUtor lim k il blplienyk (abitiij mal Ih cr fim o Imi ie*i*l K lm iu ln p m ul S e h iilr , 1957 Jo n e* nm l A ld o i, 1936 ( `xK kl am i I V i k L y , 19-IJ lle h r M m i. 19(9 Stilly i l i. PUH; Ih ip o k nml C o lo m h , 1956 C o llier. I9J3 Ibitter et n i,. 1961; lllcibcrg el ni.. 19W; G o ld n u in u , 1972: J l r m e l ei a l.. 197-1 T n ih m ii el a l., 1952; G o rd o n , 1956 O rn i ei rii.. PI76 D ipenive ir:iCl iinorcxln, vom itili^. licm orr liapc chlorinated naphthalene* 2 J t7 ,i- ic t r n d n o f iH llU iir t x l In vili G ood nnd Rem ky. I943: D w y e r. 19-16 H o fm a n n . 1 9(7; O u ld n in im . 1972 I'ctip bcial itm tM iv *y.ilnn *envry nciirojvtihy. IKfipheral m urili* 2,.',7.1bleirikliloiidlheAd Im iti . (lo h ln u m n , 1972: Jir;t%ck et u l., 197-1 K n p irn io ry .lyvlcm broneVnk, reduced viial cnjm clly leelm leul |KHt nehloroi dumo! poiy d i lori nnicd hlpltcnyl* * Ibrnder and llnoer, 1951 . W arvhu w ci n i.. 1979 a, Tlic .lympioun ami lip u lined ere pbvived hy n number of oilier Bullion. The reference* Ikied verve merely n n urnpie*, h. IV*i*Jrnu-fUMion ws reported tu black for chlnrlnnicd nnpltlhidcitc* by ('oiler (IV+l), R .D . Kimbrough