Document 9kae4yxwQzLXqbjBJr8D0XOD

CURRICULUM VITAR Norman K. Edelman, M.D. June 1981 BIRTHDATE; May 21, 937 BIRTHPLACE: New York City SEX; Male S.S.#: 088-28-3206 MARRIED: June 1959 . Ida Nadel CHILDREN: Ages 19, 16, 14 ' HOME: ' 46 Greenway Terrace, Princeton, New Jersey 08540 present position . Professor and Associate Chairman, Department of Medicine, Rutgers Medical School, College of Medicine and Dentistry of New Jersey. Chief, Division of Pulmonary Diseases, Department of Medicine, Rutgers Medical School, College of Medicine and Dentistry of New Jersey. Chief, Medical service, Middlesex General Hospital, New Bruns wick, New Jersey. . Associate Dean for Research, Rutgers Medical School, College of Medicine and Dentistry of New Jersey. Adjunct Professor of Physiology and Biophysics, Rutgers Medical School, College of Medicine and Dentistry of New Jersey. Member of the Graduate Faculty in Physiology, Rutgers University. Member of the Graduate Faculty in Biomedical Engineering, Rutgers University. 1953-1957 1957-1961 EDUCATION Brooklyn College, New York City, A.B. New York University Medical School, New York City, M.D. Honors: Alpha Omega Alpha, Founders Day Honors POO? 0)77 PRODUCED BY FORD SCF-ALLF-08551 Edelman, N.E. - 2 1963.-19*3 1963-1965 1965-1967 1967-1969 . 1969-1972 1972-1975 TRAINING AND EXPERIENCE Intern and Assistant Resident, N.Y.U. Medical Divi sion, Bellevue Hospital, New York City. Research. Associate, National Institutes of Health, National Heart Institute, Gerontology Branch. Visiting Fellow in Medicine and Advanced Research Fellow of the American Heart Association, Cardio respiratory Laboratory, Columbia University College of Physicians and Surgeons, Presbyterian Hospital, New York City. Research Associate, Cardiovascular Institute, Michael Reese Hospital and Medical Center, Chicago, Illinois. . Assistant Professor of Medicine, University of Pennsylvania; Medical Director, Respiratory Therapy Department and Chief, Pulmonary Diseases Outpatient Department, Hospital of the University of Pennsylvania. Associate Professor of Medicine and Chief, Division of Pulmonary Diseases, Department of Medicine, Rutgers Medical School, College of Medicine and Dentistry of New Jersey. SELECTED ORGANIZATIONS American Society for Clinical Investigation; American Federation for Clinical Research; American Physiological Society; American Thoracic Society; American Heart Association; Fellow, American College of Physicians; Fellow, American College of Chest Physicians 1969 1972 BOARD CERTIFICATIONS Certified in Internal Medicine Certified in Pulmonary Diseases SELECTED ADDITIONAL ACTIVITIES AND APPOINTMENTS 1963-1965 1967-1969 1971-1972 Visiting Lecturer in Physiology, University of Maryland, School of Medicine. Visiting Lecturer in Physiology, University of Chicago, School of Medicine. Consultant in Respiratory Physiology, Walter Reed Army Hospital, Washington, D.C. 800? 0176 PRODUCED BY FORD Edelman, N.H. 3 Selected Activities and Appointments (cont'd.) 1973-1^7.6 1974 1975-1979 1977 1978 1978 1979-1981 1981-1982 1981-1982 1981- Health Professions Educational Advisory^Counci1, State of New Jersey. Member, Governing Council, New Jersey Thoracic Society. Member, "Cardiovascular-Pulmonary Study Section (CVA), National. Institutes of Health. Member, Program Committee, Structure and Function Assembly,. American Thoracic Society. Member, Tuberculosis Advisory Council, State of New Jersey. President, Eastern Section, American Thoracic Society. Councellor-at-Large, American Thoracic Society. Chairman, Assembly on Respiratory Structure, Function and Metabolism, American Thoracic Society. Member, Program Committee, American Thoracic Society. Member, Editorial Board, Journal of Applied Physiology. SELECTED MEDICAL SCHOOL, COLLEGE . AND HOSPITAL COMMITTEES Executive Faculty Council .* Admissions Committee Academic Standing Committee Vivarium Committee . . Committee for the Protection of Human Subjects Medical Therapeutics Committee College-wide Faculty Advisory Committee for'Computer Services Faculty Advisory Committee for Planning School Expansion College-wide Faculty Advisory Committee for Planning South Jersey Medical School ,` College-wide Faculty Advisory Committee for Faculty Utilization Study Committee to Review Functional Alternatives to the Immediate Development of a Teaching Hospital to be Constructed upon the River Road Campus in Piscataway Medical Board, Middlesex General Hospital Joint Conference Committee, Middlesex General Hospital POO? 0)79 PROD) 1CFD PV rrum Edelman, N.K. 4 BIBLIOGRAPHY Papers :-n . 1. Relationship between chest wall and pulmonary compliance and age. C. Mittman, N.H. Edelman, A.H. Norris and N.W. Shock, J. Appl. Physiol. 20:1211-1216, 1965. 2. The effects of cigarette smoking upon spirometric performance of community dwelling men. N.H. Edelman, C. Mittman, A.H. Norris, B.H. Cohen and N.W. Shock, Amer. Rev. Resp. Pis. 94:421-429, 1966. 3. Effects of respiratory pattern on age differences in . .ventilation uniformity. N.H. Edelman, C. Mittman, A.H. 7 Norris and N.W. Shock, J. Appl. Physiol. 24:49-53, 1968. 4. Extravascular'lung water-in cor pulmonale. G.M. Turino, N.H. Edelman', R.M. Senior, E.C. Richards and A.P. Fishman, Bull. Physio-Path. Resp.-4:47-64, 1968. -- 5. Peripheral chemoreflexes in the regulation of breathing of high altitude natives. S. Lahiri and N.H. Edelman, Respir Physiol. 6:375-385, 1969. ' 6. Blunted hypoxic;drive-to-ventilation in subjects with life long- hypoxemia*- S\ Lahiri, N.H. Edelman, N.S. Cherniack and A.P. Fishmah~,~~Ted. Prbc~.~2 8 :T289-12951969 . ' . ' ?.i.-..Response of- goats to acute, chronic and life-long hypoxia. ;.CcNH,:Edelman, N.S-.- Cherniack, S.' Lahiri and A.P. Fishman, - -Fed. Proc. 28:1223-1227, 1969. fis:Pattern-of.discharge-of respiratory neurons during systemic vasomotor waves. N.S. Cherniack, N.H. Edelman and A.P. Fishman, ' i: Amer.; J : Physiol. 217:1375-1383-, 1969. . 9.'. The. effects of abnormal sympathetic nervous function upon the Ic.yentilatory; response to hypoxia:.-. N.H . . Edelman, N.S,. Cherniack, 5 ScLahiri, E. Richards and A.P. Fishman, J. Clin. Invest. Icr.9-:il53rll65-,. 1970;: -. r: - : -- . 10 .-The;-blunted; ventilatory response to hypoxia in cyanotic con..sigenital heart disease. N.H., Edelman, S. Lahiri, L. Braudo, ..'c;N-iS;; Cherniack and. A.P* Fishmans-- New. Eng ._ J . . Med.. 282:405-411, 1970 ,2 exchange across- spleen durinq asphyxia. N.S. Cherniack, N.H. Edelman and'A.P."Fishman,' Amer.'j. Physiol/ 219:1585-1589,.1970. 12. Hypoxia arid hypercapnia as respiratory stimulants and depressants. N.S. Cherniack, N.H. Edelman and S. Lahiri, Resoir. Phvsiol. 11:113-126, 1970-71. R0O2 01e0 PRODUCED BY FORD XT Edelman., N.H. - 5 (Papers) i.3! Experimental cardiogenic shock: Pulmonary performance after acute myocardial infarction."" N^H. Edelman, H.J. Gorfinkel, S. Liuch, A. Gottschalk, L.J. Hirsch and A.P. Fishman, ------ ftmer.' J. Physiol. 219:1723-1730, 1970. 14. Regulation of respiration in goat and its adaption to chronic and life-long hypoxia. S. Lahiri, N.S. Cherniack, N.H. Edelman and A.P.' Fishman, Respir. Physiol. 12:388-403, 1971. 15. Control.of cerebral blood flow in the goat? role of the carotid rete. N.H. Edelman, P. Epstein, N.S. Cherniack and A'.P.'Fishman, Amer. J. Physiol. 223:615-6191972. 16. -Serial, changes in CO2 storage in tissues. N.S. Cherniack, ' Tuteur, N.H.. Edelman and A.P. Fishman, Respir. Physiol. lKil^-1'41, 1972. .. 17. Ventilatory responses to transient hypoxia and hypercapnia in man'.. !n.H'. Edelman, P.E. Epstein, S. Lahiri and N.S. Cherniack, &aspir,. Physiol. 17 :302-314, 1973. ~ 18. Early.detection, of chronic pulmonary disease. N.H. Edelman, ` N.NV Stanley, and'. A.P. Fishman, Prevent. Medicine 2:34-42, p.73.:; * . - .19 The. effect of. anemia on the. ventilatory response to transient ' ahd_ steadyrstate hypoxia. 'T.V^. . Santiago, N.H. Edelman and A'.P; Fishman',' J.: Clin. Invest." 55 :410-418, 1975. `- 20. Allergic bronchopulmonary aspergillosis - Evidence of limited .'tissue', invasion. D.J.'Riley, J.W. Mackenzie, W.E. Uhlman and N.B. Edelman, Amer.`Rev.'Resp. Pis. 111:232-236, 1975. 21. Control of breathing in uremia: .Ventilatory response to C02 ` feffcer hemodialysis-. R.V7. Hamilton, P. Epstein, L.W. Henderson, N;.B:. Edelman.and A.P. Fishman, J. ApdI. Phvsiol. 41:216-222, 9^9 7* . - - --------- - '. 22. J/uft's. syndrome:O2 cost .of exercise and chemical control of breathing'.- NTH. ^Edelman, T.VI Santiago and H.L. Conn, Jr., j. Abpl'. Physiol'. 39:857-859, 1975. --r--------------------- 23. Mechanism of the ventilatory response to carbon monoxide of unanesthetized goats. N.H. Edelman, T.V. Santiago and . DOblar;, 'Morphology and Mechanisms of Chemoreceptors, fed'. A:sV Paintal, ` 197 6. ' ------------' 24. Complications.of.the obesity-hypoventilation syndrome in ' Childhood. d:j. Riley, T.V. Santiago and N.H. Edelman, Amer. J. Pis. Child: -13 0 : 67-1-674 ,--1975___ 25. Respiratory complications of obesity. D.J. Riley and N.H. Edelman, Resp. Therapy 6:55-56, 1976. -- ........-- ----- 900? eirtl PRODUCED BY FORD toexman, N.n . - o ipapersj 26". Mechanism of the ventilatory response to carbon monoxide. T.V. Santiago and N.H. Edelman, J. Clin. Invest. 57:97798^ 1976. 27. Responses of asthmatic patients to aerosolized isoproterenol . inhaled at different lung volumes. D.J. Riley, B.W. Weitz and N.H. Edelman, Amer. Rev. Resp. Pis. 114 :509-515 1976. 28. Effect of hypoxia on small vessel blood content of rabbit brain. H.R. Weiss and N.H. Edelman, Microvasc. Res. 12: 305-315, 1976. .. 29. Control of breathing during methadone addiction. T.V. Santiago, A.C. Pugliese and N.H. Edelman, Amer. J. Med. 62:347-354, 1977. 30. Blunted respiratory drive in congenital myopathy. D.J. Riley, T.V. Santiago, B. Schall and N.H. Edelman, Amer. J. Med. 63: 459-466, 1977. . 31. Correlation between the ventilatory and cerebrovascular re sponses to inhalation of carbon monoxide. D.D. Doblar, T.V. Santiago and N.H. Edelman,-J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 43 (3):455-462, 1977. ' . 32. Ventilatory responses to hypercapnia and hypoxia during con tinuous aspirin ingestion. D.J. Riley, B. Legaweic, T.V. Santiago and N.H. Edelman, J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 43:971-976, 1977.. . 33. The effects of inhalation of carbon monoxide on some aspects of neuromechanical ventilatory control. N.H. Edelman, T.V. Santiago and R. Chapman, in: The Regulation of Respiration During Sleep and Anesthesia, R.S. Fitzgerald, H. Gautier and ` S. Lahiri, ed., Plenum Press,1 1978. 34. A microcomputer-based data acquisition and analysis system for CC>2 rebreathing studies. M.A. Goegelman, B.G. Min, . D.R. Donchin, W. Welkowitz, T.V. Santiago and N.H. Edelman, Biotelemetry and Patient Monitg. 5:193-205, 1978. . 35. Frequency domain analysis of O2 stores during hypoxia in the goat. B.G. Min, D.D. Doblar, W. Welkowitz and N.H. Edelman, Ann. Biomed. Engrg. 6:352-366, 1978. 36. Effects of morphine on the ventilatory response to exercise. T.V. Santiago, J. Johnson, D.J. Riley and N.H. Edelman, J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. ' ' 47:112-118, 1979. ' !^ ! 37. The effects of graded reduction of brain blood flow on ven- . tilation in unanesthetized ccats. R.W. Chapman, T.V. Santiago and N.H. Edelman, J. AddI. Physiol.: Resoirat. Environ. Exer cise Physiol. 47:104-lii, 1979. * PRODUCED BY FORD' Edelman, N.H. - 7 (Papers) 38`. Dynamic characteristics of cerebral blood flow response to sinusoidal hypoxia. D.D. Doblar, B.G. Min, R.W. Chapman, E.R. Karback, W. Welkowitz and N.H. Edelman, J. Appl. . Physiol.: Respirat. Environ. Exercise Physiol. 46:721-729, 1979. : ^ ; 39. Enhanced responses to aerosolized bronchodilator therapy in asthma using respiratory maneuvers. D.J. Riley 1 'R.`T. Liu and N.H. Edelman, Chest 76:501-507, 1979. 40. Effects of graded reduction of brain blood flow on chemical control of breathing. R.W. Chapman, T.V. Santiago and N.H. Edelman, J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 47:1289-1294, 1979. ` 41. Ventilatory control in parents of victims of sudden-infant death syndrome. P.L. Schiffman, R.E. Westlake, T.V. Santiago and N.H. Edelman, N. Engl. J. Med. 302:486-491, 1980. 42. Prevention of collagen deposition following pulmonary oxygen toxicity in the rat by. cis-4-hydroxy-L-proline. D.J. Riley, R.A. Berg, N.H. Edelman and D.'J. Prockop, J. Clin. Invest. 65:643-651, 1980. -- 43. Interaction between chemical ventilatory drive and respira tory compensation for flow-resistive loading. D.D. Doblar, R.W. Chapman, T.V. Santiago and N.H. Edelman, Chest (Supole- ment) 77:297-298, 1980. * 44. Respiratory consequences of methadone: The response to added resistance to breathing. T.V. Santiago, K. Goldblatt, K. Winters, A.C. Pugliese and N.H. Edelman, Airier. Rev. Resp. Pis: 122:623-628, 1980. . 45. Brain hypoxia and control of breathing: Neuromechanical con trol. R.W. Chapman, T.V. Santiago and N.H. Edelman, J. Appl. Physiol.: Resoirat. Environ. Exercise Phvsiol. 49:497-505, iTso:---------------------------------------------------------------------------------- . 46. Positional hypoxemia in unilateral lung disease. C- Remolina, A.U. Khan, T.V. Santiago and N.H. Edelman, N. End. J. Med. 304:523-525, 1981. ` 47. Respiratory flow-resistive load compensation during sleep. T.V. Santiago, A.K. Sinha and N.H. Edelman, Amer. Rev. Reso. Pis. 123:382-387, .1981. . 48. Endorphins and control of breathing: Ability of naloxone to restore the impaired flow-resistive load compensation in chronic obstructive pulmonary disease. T.V. Santiago, C. Remolina, V. Scoles and N.H. Edelman, N. End. J. Med. 304 : 1190-1195, 1981. " n 0 0 ? 01s*? PRODUCED BY FORD Edelman, N.H. - 8 (Papers) 49. Prevention of bleomycin-induced pulmonary fibrosis in the hamster by cis-4-hydroxy-L-proline. D.J. Riley, J.s. Kerr, . R.^. Berg, B.D. Ianni, G.G. Pietra, N.H. Edelman and D.J. ProCkop, Amer. Rev. Resp. Pis. 123:388-393, 1981. 50. The effect of positive end-expiratory pressure (PEEP) venti lation on cerebrospinal fluid pressure and cerebral blood flow. D.D. Doblar, T.V. Santiago, A.U. Khan; D.J. Riley and N.H. Edelman, Anesthesiology (in press). . 51. Hypoxic arousal in the intact and carotid chemodenervated sleeping cat. J.A. Neubauer, T.V. Santiago and N.H. Edelman, J. Appl. Physiol.: Respirat. Environ. Exercise Physiol, (in press). 52. Brain hypoxia and control of breathing: Role of the vagi. R.W. Chapman, T.V. Santiago and N.H. Edelman, J. Appl. Physiol.: Respirat. Environ. Exercise Physiol, (in press). 53. Beta-aminopropionitrile prevents bleomycin-induced pulmonary fibrosis in the hamster. D.J. Riley, J.S. Kerr, R.A. Berg, B.D. Ianni, G.G. Pietra, N.H. Edelman and D.J.-Prockop, Amer. Rev. Resp. Pis, (in press). ecc? oi8<* PRODUCED BY FORD Contributions to Books: 1. Clinical aspects of the chemical control of breathing. N-H. Edelman and T.V. Santiago, in: Pulmonary Care, R.F. Johnston, ed, New York, Grune & Stratton, 1973, pp 51-64. ' 2. Chronic bronchitis and emphysema. N.H. Edelman, D.J. Riley and T.V. Santiago,, in: Current Therapy, H.F. Conn, ed, W.B. Saunders, Philadelphia, 1977, pp 107-112. 3. The lungs and ventilation in uremia. N.H. Edelman, in: Pulmonary Diseases and Disorders, A.P. Fishman, ed, McGraw- Hill, New York, 1979, pp 1347-1356. 4. Cor Pulmonale. N.H. Edelman, in: Practice of Medicine, Vol. VI, Chapter 11, Harper and Row, 1979. 5. Brain blood'flow and the control of breathing. N.H. Edelman, irtj .Handbooks of Physiology, Section 3: Respiration, Vol. IV, Control of Breathing, American Physiological Society (in press). 6. Contemporary Issues in Pulmonary Disease. N.H. Edelman (Series Editor), Churchill Livingstone (in preparation). 7. Conte"mporary Issues in Occupational Lung Disease. N.H. Edelman (Editor), Churchill Livingstone (in preparation). B01.ir 't)B5 PRODUCED BY FORD Edelman, N.H. 10 Material Presented at Meetings and.in Abstract Form: 1. The effect of age upon chest wall and pulmonary compliance. C. Ilittman, N.H. Edelman, A. Norris and N.W. Shock, Fed. . Proc. 23(1) :466, 1965. . 2. Non-uniform pulmonary ventilation. N.H. Edelman, C. Mittman, A. Norris- and N.W. Shock, Fed. Proc. 24(1)466, 1965. 3. Pulmonary diffusing capacity measured by sequential steadystate and washout methods. C. Mittman, N.H. Edelman, and N.W. Shock, Fed. Proc. 25(1)s325, 1966. .4 Abnormal ventilatory and circulatory response to hypoxia in familial dysautonomia. N.H. Edelman, E. Richards and A.P. Fishman, J. Clin. Invest. 46:1051, 1967. 5. Extravasciilar lung water in cor pulmonale. N.H. Edelman, R. Senior, G.M. Turino, E. Richards and A.P. Fishman, Circulation 36(11):101, 1967. 6. Ventilatory response to hypoxia in cyanotic congenital heart disease. N.H. Edelman, S. Lahiri, N.S. Cherniack, L. Braudo and A.P. Fishman, Clin. Res. 16:369, 1968. ' 7. Ventilatory response of unanestheti2ed goats to acute and chronic hypoxia. S. Lahiri, N.H. Edelman, N.S. Cherniack and A.P. Fishman, Fed. Proc. 27(2):328, 1968. 8. Role of the spleen in 0- storage during asphyxia. N.S. Cherniack, N.H. Edelman, G. Longobardo and.A.P. Fishman, J. Clih. Invest. 47:18a, 1968. . 9. Role of the sympathetic nervous system in the ventilatory response to hypoxia. N.H. Edelman, N.S. Cherniack, S. Lahiri and A.P. Fishman, Proc. Internat. Union of Physiol. Sci. 7:122, 1968. 10. Rete mirabile of the goat. N.H. Edelman, C. Reiman, R. Pick and A.P. Fishman, Circulation, 38(6):69, 1968. 11. Distribution of pulmonary blood flow in an experimental model of cardiogenic shock. N.H. Edelman, S. Lluch, L. Hirsch, A. Gottschalk and A.P. Fishman, Circulation 38(6):70, 1968. 12. Respiratory adaptations to hypoxia. S. Lahiri, N.H. Edelman, -N.S. Cherniack and A.P. Fishman, Clin. Res. 17:477, 1969. 13. Site of interaction in the ventilatory response to hypoxia and hypercapnia. N.H. Edelman, S. Lahiri, P. Epstein and N.S. Cherniack, Fed. Proc. 28:337, 1969. * 00 01cie> PRODUCED BY FORD W ' Edelman, N.H.- 11 (Abstracts) . .14. 'Altitude acclimatization of ruminants and hypoxic sensiti- ' -- "vity. S. Lahiri, N.S. Cherniack, N.H. Edelman and A.P. Fishipan, Fed. Proc. 29:591, 1970. '. . 15. The effects.of hypoxia and hypercapania on respiratory neuron activity and cerebral metabolism. N.S. Cherniack, N.H. Edelman, S. Lahiri, Aspen Emphysema Conference, 1970. 16. Acute buffering of C02 by tissues in vivo. N.S. Cherniack' N.H. Edelman, P.G. Tuteur and T.J. Trueb, J. Clin. Invest. 49:18a, 1970. 17.- Brain energy metabolism limiting the ventilatory response to . hypoxia and hypercapnia. N.H. Edelman, P.E. Epstein and N.S. Cherniack, Fed. Proc. 30:269, 1971. 18. Response rates of ventilation and cerebral blood flow to C02 . -in normal goats and abnormal man. N.H. Edelman, P.G. Tuteur, L. McHenry and N.S. Cherniack, Clin. Res. 19:510, 1971. 19. The-effect of impairment of 02 delivery on the aerobic metabolism of brain and skeletal muscle. N.H. Edelman, P.G. Tuteur, P.E. Epstein, N.S. Cherniack and A.P. Fishman, 14th Aspen Conference on Emphysema, 1971. Chest 61:495, 1972. 20. The effect of lung volume on respiratory drive during hyper-r . ' Tcapnia. P.G. Tuteur, P.E.' Epstein, N.H. Edelman, and N.S. Cherniack, 14th Aspen Conference on Emphysema, 1971. Chest . :61, 19 72. ' 21. ' The transient ventilatory response to hypoxia and hypercapnia. N.S. Cherniack, T.J. Trueb, N.H. Edelman, S. Lahiri and A.P. Fishman, XXV International Congress of Physiological Sciences, 1971. - . 22. Ventilatory response to transient hypoxia in anemia. T.V. Santiago, and N.H. Edelman, Fed. Proc. 31:3.71, 19.72. 23. " Control of breathing in uremia: enhanced ventilatory response "to C02 following hemodialysis. R. Hamilton, P.E. Epstein, L.W. Henderson, N.H. Edelman and A.P. Fishman, J. Clin. Invest. 51:41a, 1972. 24. Iriapparent congenital myopathy presenting as chronic hypo ventilation. N.H. Edelman, R. Daniele and T.V. Santiago, . Amer; Rev. Resp. Pis. 105:984, 1972. * 5. Stimulation of ventilation by carbon monoxide. T.V. Santiago, and N.H. Edelman, Clin. Res. 21:671, 1973. 8002 0187 PRODUCED BY FORD Edelman, N.H. 12 (Abstracts) 26. Mechanisms of Cheyne-Stokes respiration. N.S. Cherniack, S. Lahiri, N.H. Edelman and A.P. Fishman, Clin. Res. 21:736, 1973*. . 27. Mechanism of the ventilatory response to carbon monoxide. T.V. Santiago and N.H. Edelman* Fed. Proc. 33:440, 1974. ' , 28. Control of breathing during methadone addiction. T.V. Santiago and N.H. Edelman, J. Clin. Invest. 53:70a, 1974. 29. Pattern and predictability of 02-induced hypercapnia in . COPD. T.V. Santiago and N.H. Edelman, presented at the 1975 Annual Meeting of the American Thoracic Society. _ 30. Effects of morphine on the ventilatory response to exercise. T.V. Santiago, J. Johnson and N.H. Edelman, Clin. Res. 23(3):3 51A, 1975. ~ 31. Circulatory determinants of CO~induced hyperventilation. D. Doblar, T.V. Santiago and N.H. Edelman, Fed. Proc. 34 (3) :430, 1975. ... 32. Role of carotid body, arterial and cisternal fluid pH in the acclimitization to chronic hypoxia. S. Lahiri, N.S. Cherniack, N.H. Edelman, and A.P. Fishman, The Physiologist 18:284, 1975. 33. Effect of morphine on the cerebral blood flow responses to hypoxia and hypercapnia. R.W. Chapman, T.V. Santiago, A.U. Khan, and N.H. Edelman, Fed. Proc. 35:719, 1976. . 34. The generation of variable amplitude and frequency sinusoidal arterial P02 for frequency response analysis. D.D. Doblar, . B.G. Min, E.R. Harback, W. Welkowitz, and N.H. Edelman, Proc. 29th ACEMB, 356, 1976. ' 35. Frequency analysis of the cerebral blood flow response to hypoxia. D.D. Doblar, R.W. chapman, B.G. Min, W. Welkowitz, and N.H. Edelman, Fed. Proc. 36:439, 1977. 36. Effect of reduction of cerebral blood flow on the ventilatory response to hypoxia. R.W. Chapman, T.V. Santiago, and N.H. Edelman, Fed. Proc. 36:425, 1977. ' 37. Effects of reduction of cerebral blood flow on ventilation and ventilatory responsiveness to C02, T.V. Santiago, R.W. Chapman, and N.H. Edelman, Clin. Research 25:422A, 1977. 38. The effects of positive end-expiratory pressure ventilation (PEEP) on cisternal cerebrospinal fluid pressure and cerebral blood flow. T.V. Santiago, D.D. Doblar, A.U. Khan, D.J. Riley, -and N.H. Edelman, Amer. Rev. Resp. Pis. 115(4, pt 2):159, 1977. 8002 0188 PRODUCED BY FORD Edelman, N.H. 13 (Abstracts) 39. * The dose-res-ponse relationship of asthmatics to isoproterenol at differing lung volumes. D.J. Riley, B.W. Weitz and N.H. Edelman, Amer. Rev. Resp. Dis. 11S (4 , pt II):369, 1977. 40. Ventilatory responses to hypercapnia and hypoxia during continuous aspirin ingestion. D.J. Rilev, B. Legawiec, T.V. Santiago, and N.H.. Edelman, Amer. Rev. Resp. Dis. 115 (4 , pt II):369, 1997. . 41. Role.of brain blood flow in the control of breathing: Effects of flow limitation. N.H. Edelman, R.W. Chapman, and T.V. Santiago, 20th Aspen Lung Conference, 1977. 42. Effects of carbon monoxide on neuromechanical ventilatory control. R.W. Chapman, T.V. Santiago and N.H. Edelman, Fed. Proc. 37:530, 1978. . 43. The cerebral blood flow response to C02 using frequency response analysis. D.D. Doblar, R.W. Chapman, M. Konwiser, B.G. Min, and N.H. Edelman, Fed. Proc. 37:873, 19.78. 44. Role of the vagus in the respiratory response to brain hypoxia. R.W. Chapman, T.V. Santiago, and N.H. Edelman, . Amer. Rev. Resp. Dis. 117(4, 'pt II):415, 1978. 45. Effect of acute and chronic methadone use on respiratory response to mechanical loading. T.V. Santiago, K. Goldblatt, K. Winters, A.C. Pugliese,-and N.H.- Edelman, Amer. Rev. ResD. Dis. 117(4, pt II), 1978. `| " 46. Enhanced responses to aerosolized bronchodilator therapy in asthma using respiratory maneuvers. D.J., Riley, R.T. Liu, and N.H. Edelman, Chest 74:348A, 1978. 47. Abnormalities in control of breathing with inability to compensate for an inspiratory resistance in parents of sudden infant death syndrome (SIDS) victims. P.L. Schiffman, R.E. Westlake, T.V. Santiago, and N.H. Edelman, Clin. Res. 27: 493A, 1979. . 48. The respiratory responses to continuous inspiratory flowresistive loading of sleeping cats. T.V. Santiago, A.K. Sinha, and N.H. Edelman, Fed. Proc.'38:1299, 1979. . 49. Use of a proline analogue to prevent deposition of collagen in acute oxygen lung injury in rats. D.J. Riley, N.H. Edelman, R.A. Berg, and D.J. Prockop, Amer. Rev. Reso. Dis. 119:353, . -1979. * 50 Interaction between chemical ventilatory drive and respiratory compensation for flow-resistive loading. D.D. Doblar, R.W. Chapman, T.V. Santiago, and N.H. Edelman. Presented at the 22nd Aspen Lung Conference, 1979. Chest (Suppl.) 77:297 , 1980. 80C2 01bP PRODUCED BY FORD Edelman, N.H., - 14 (Abstracts) SI*. A microcomputer-based data acquisition and analysis system "for CC>2 rebreathing studies. M.A. Goegelman, B.G. tMin, "D.R. Donchin, W. Welkowitz, T.V. Santiago and N.H. Edelman, Proc. 30th ACEMB. 52. Brain blood flow and ventilation during euoxic and hypoxic sleep. T.V. Santiago, E. Guerra, A.K. Sinha and N.H. Edelman, Clin. Res. 28:43iA, 1980. 53. Hypoxic arousal in sleeping cats. J.A. Neubauer, T.V. Santiago and N.H. Edelman, Amer. Rev. Resp. Pis. 121(4, pt II):383, 1980. 54. .Endorphins and control of breathing: Naloxone reverses the ' 'impaired flow-resistive load compensation in COPD. T.V. .'Santiago, C. Remolina, V. Scoles and N.H. Edelman, Amer. Rev. bfeesp. Pis. 123(4, pt II):211, 1981. .55. 'Regional brain blood flow during isocapnic hyperpnea induced f&y 'Simulated exercise. J.A. Neubauer, D.A. Strumpf and N.H. 'Edelman, Fed. Proc. 40(3, pt I):567, 1981. 56. .Effect of sixweeks of protein deprivation on rat lung. J.S. "Kerr; S. Lanza-Jacoby, D.J. Riley, R.A. Berg, N.H. Edelman and Pr-ockop,-Fed. Proc. 40(3, pt I): 592, 19 81. 57. ^Oxygen'toxicity produces alveolar overdistension which pro gresses.to emphysema. D.J. Riley,. M.J. Kramer, J.S. Kerr, . .R.A.'VBerg, B.D. ianni,'nIh." Edelman and D.J.' Prockop, Fed, ^oc: 40(3, pt I) :767, 1981. . 58. TBeta-jaminopropionitrile'administration prevents lung mechanical ^changes and increased lung collagen content in the bleomycin- treated hamster. D.J. Riley, J.S. Kerr, R.A. Berg, B.D. Ianni, ' N.H -- Edelman and .D.J. Prockop, Amer. Rev. Reso. Dis. 123:221, . ..... ' - ' ------1981 59. Beta-jaminopropionitrile'administration inhibits lung collagen accumulation produced by oxygen toxicity in the rat. D.J. Riley, M.J. Kramer, J.S. Kerr, R.A. Berg, B.D. Ianni, N.H. Edelman ^and D.J. ..Prockop, Clin. Res. 29:451A, 1981. 8002 0190 PRODUCED BY FORD