Document 93w2aQaZoqKrvDRvgXjXM3arp

LDTOAIfE-AHOCLOR* COMBIMATIOMa Monsanto Chemical Co^>any Phosphate Division 3c. Louis, Missouri In recent news releases the Bureau of Entomology awe pleat Quarantine, h. 3. Department of Agriculture, BeltiTllle, ifcryland, &unounoed that results of laboratory and preliminary trial studies show icorked increasa In the effootlTe lnseetleldal life of lindane when ohlorlnated polyphenyls (Monsanto's Aroelera) are Incorporated In the toxicant formulation. A natter of ohlorlnated polyphenyla were tested; test results were obtained with Arcelor 5460. For specific purposes where a very tacky deposit la desired. It nay ba possible that Aroelar 4465, also a resin, may be of Interest. If a "wet" deposit la desired, perhaps ohlorlnated biphenyls suoh as Aroolors 1254, 1260 and 1262, which are viscous liquids, will give the desired effact. Lindane is a wall established pestioidal ehealoal. When applied as a residua It nay leave an unsightly crystalline deposit and because of Its relatively high vapor pressure. Its lnseetleldal value dissipates within a few weeks. The Aroelars have good solvent notion on lindane which accounts for their Improving the appearance of the pestioidal residue. Moreover, the Aroolors function as relatively non-volatile, nonoxldlzabls, non-flaaaabis bonding agents for lindane. Imparting strong adhesion to all sorfaeeu nnd reducing the evaporation of lindans to a marked degree. The high resistance of Aroolors to water and corrosive laflueneee, no doubt, aoooints for the unusually good weather durability of the lindane-Aroolor residue as noted In the preliminary work. Although the biphenyl Aroolors, and especially the lower ohlorl nated mutters of the series are known to poaaeas nativity as loualoldee, mltlcldes, larvloldes and show synarglatla action on nicotine, these properties seen to diminish with higher ehlcrl- Trade nans, (chlorinated biphenyl and 0hioriented polyphagia) Reg. 0. S. rat. Office. HONS 061744 Pag* 2 nation and alao seem less prevalent in the bcrphonyl base Aroolors such as Aroelor 5460. Sjmnrglaa, howuvnr, cannot be rea dily predloted and the possibility or synergism in this Aroolorllndane mixture la at the present ti?e ixi-iog investigated by the Bureau of Bntonulogy and Plant Quarantine. Understanding of the dermatology and toxicology or ax<i\ Important In their handling and use In Insecticidal fo: 'r.tlofM, With reference to Monaanto's Teohnloal Bulletin P-115, .Mge 19 reported data indloatea that Aroelors 1254 and 5460 shored no prlaary Irritancy or aecairlsation when tested by standard sicln patob teata. Although ths vapor pressure of Aroelors la relatively low, if tho materials ara heated sufflolently to give off vapors It should be noted that such vapors bear a degree of toxicity and should not be breathed continuously, as Indicated in greater detail In Bulletin P-115. Experiments! Worlc and Formulations 50 to 200 milligrams of lindane per square foot of surface has given good Insect eontrol on nonporoua surfaces. The ratio of lindane to Aroelor 5460 has been varied fron ltl to 1(4. For aost purposes a 111 or a 1;2 mixture la satisfactory. Formulation* as used In the Bureau's experiments aret l) For application as a solution. Lindane 5 parts by weight Aroelor 5460 5 parte by weight Carbon Tetraohlorld750 parte by weight 2) For application as an emulsion. Liadaas Aroelor 5460 Xylene Triton X-100 20 parts by weight 20 parts by weight 100 parts by weight 3 peris by weight To obtain a stable lj* lindane emulsion, mix 143 parts by wslght of the above ooneenferate to 1857 parts by weight of water. 3) For use as a nreasurlsed sorer. a) Lindane Aroelor 5460 Methylene chloride Freon 12 5 parts by weight 5 parts by wslght 40 parte by weight 50 parts by weight * Carbon tetrachloride la toctlo and should be bandied with ex treme caution. Less toxic solvents are being studied. I I L jLt MOWS 061745 .'age 3 *>) r.iixlane Aroolor 5460 Cyclohexanone Ortho dlehlorobonzene -'MOU 12 5 parts by woight 5 part3 by weight 10 parts by '.wlglit 35 parts by weight 45 parts by './eight The Bureau pacpla do not '/ant these formulations or roau.1 .a with them to be xeuatrued as a r-jooamewlatIon for use a a the work la In the laboratory stag* tad has not had extensive field testing. :fct{K.Tiwatai_\J3 ilta - Aamrlean Hoachea Using Formulas 3a or 3b, tae toxicant was applied onto a painted wall depositing about 200 eg./sq.ft, of lindane and a libs amount of Aroelor o 'l60. At the ti-we of this writing, the toxicant coat Is one month old, and It still gives 90 - 100J< kill of American roaches when the roeohes contained la a petrl dish are placed against the surface of the treated wall for two hours. The research team found that the lindane-Aroclor 5460 mixture (used at the rate of 50 tag. of aotual lindane per eq. ft.) would kill 800 of all cockroaches exposed for 2 hours to a 60 day old treated surface. It remained lethal to 66$ of the roaohea after 90 dears. Regular lindane sprays used at the same rate, killed only fyf of the roaches after 6o days. House Files Deposits of ?5 mg. of lindane pins 25 mg. of Aroelcr f>460 applied from carbon tetrachloride onto glass and alminum (hard surfaces) give lOCft kill of normal bouse files exposed for 2 hours to these treated surfaces after they bed aged 18 weeks, the duration of the test. The surfaces are still equally active and the test la being oontlnned. Without the Aroelor the hard surfaces treated with lindens alone would be effestive only about oaa week. A lindane plus Aroelor mixture sprayed as an aerosol onto leaves of a willow tree continues to kill house files after 2 months outdoor weathering. Careful inspection of the treated leaves shows that tha toxloant la held firmly to the surface sad act withstanding rain and weather, the coating rnmlns In good con dition. Also, within limits of a preliminary lnepeetlam therm does net seem to be Injury to the willow leaves. MONS 061746 Pag* 4 Conclusion According to tb*a* laboratory testa, it 1* believed that Aroelor oay increase tha effeotire Ufa of lindane, 10 to 20 tines. Since Aroolar* ar* relatively very inexpensive, their urn with lindane mold offer a great economic value. in addition to oa* with lindane, the Aroelore any be equally ueeful with a wide var iety of other Insecticidal agents. Studies with Aroelore are continuing at the Bureau of Bateaology and Plant Quarantine and It le understood that a paper ooverl^ this work will be given at the Deeehber 15-18 nesting of the Aaerleaa Association of Eeononle Satenologlsts at Philadelphia, Pennsylvania. Byi P. a. Benignus Monsanto Chealeal Co. Dates 11/26/52 TO 73 HONS 061747