Document 93N6YmoxZaVEE7a9g41owqbKV

J )- H o n By Victor John Yannacone, Jr. W . Keith Kavenagh and Margie T. Searcy their esters and salts, including 2,4-D and 2,4,5-T . In May 1947, the D o w . Chemical Co. brought a declaratory judgment action against American. C hem ical P a in t C o. seeking*,*; declaration of the invalidity of the/ Franklin D. Jones patent under which: Shortly after World War II, work on the American Chemical Paint Co. phenoxy herbicides at the New York was m aking 2,4-D and 2,4,5--*T State Agricultural Station was sup- turn American Chemical sued Dow ported in part by a grant from The for patent infringem ent and sought Dow Chemical Co. which also sup- an injunction against further sales of plied the chemicals. 2,4-D and 2,4,5-T by Dow. The effectiveness of chlorophenoxy Between 1940 and 1962 many of" com pounds such as 2,4,5-T and the chemical companies which even- 2,4-D as herbicides had been first tually supplied " Agent Orange" to dem onstrated in 1944 by the US De- the military for use in Southeast Asia partment of Agriculture (USDA) at were experimenting with phenoxy B eltsv ille an d C am p D e tric k , herbicides and patenting th e re**i*ffl! M aryland. By 1951 tests at C am p their research. ' T ` Detrick determ ined that the herbicide In 1952 Dow r e p o r te d & y jjj^ jf ta i ' of choice for military defoliation teron Brush Killer" ^ a$ .a operations was an equal mixture of . the butyl esters o f 2,4-D and 2,4,5-T . ----------------:-------------------- :-- r . The effectiveness of this form ulation Victor John Yannacone, Jr.,- o f was established in 1959 in a large- Yannacone and Yannacone, P.C., scale test over four square miles at Pathogue, New York, is managing Fort D rum , New York. In 1961 the partner o f Yannacone & Associates D epartm ent of Defense (DOD) con- and lead counsel fo r the plaintiffs in ducted large-scale aerial application re "Agent Orange" Product Liability trials o f the herbicide in Southeast Litigation, M D L 381. Asia. W. Keith Kjgvenagh, Ph&jt In December 1946, Franklin D. is a partnetM Ye p f ^ ^ m Jones sold to American Chemical naconei^fP. B^^ ^ ,' Paint Co. a US patent for methods of killing weeds with halogenated phe- f i r m .Q f : 5 g q r ^ ^ ^ ^ oe y ^ 0 ^ d j ^ ^ ^ 2 .4 - D and 2,4,5-T, clearly estab dustrial collaboration. Ordinarily, in lishing that 2,4-D and 2,4,5-T had military R&D we have a military con been combined and marketed com cept that leads to the statement of a m ercially long before " Agent military requirement, technical char O range" was formulated for the gov acteristics, p erform ance sp ec ifi ernment. cations, and other strictly delimited When the DOD turned to the aspects. In this program we do not American chemical industry for de have rigidly specified characteristics. foliants suitable for use in Vietnam, 1 have stated some of the broad re the government sought an herbicide quirements that a successful defoli which was " immediately available in ating chemical should have, but q u a n t i t y " a n d ` `n o n to x ic to within this general framework we will hum ans.'' Commercial mixtures of accept and use materials that will do a 2 .4 - D and 2,4,5-T were tried in field job for us. In a few years it may be tests because the government had that we will come up with more defi been assured by the manufacturers nite specifications but at the moment that " these chemicals have been we simply solicit the assistance o f you known and used in the US for more gentlemen [the defendants present] in than 15 years, and are considered safe finding materials that can be used to animals and hum ans...." From successfully within the reasonably 1961 to 1963, Dow, Ansul, and Mon broad and general guidelines that santo were the main sources of her General Delmore has stated and that I bicides for the screening field tests. have repeated." At the " First Defoliation Con The government had not developed ference" conducted by the DOD, any chemical defoliants for use in Fred J . D elm ore, Com m anding Vietnam and had no specifications in G en eral, US A rm y, Edgew ood 1964. The DOD invited the agrichem Arsenal, alerted the chemical com ical companies to compete in the panies in a tten d a n ce--P en n salt, development of a fast-acting and safe General Anoline & Film Corp., Ethyl herbicide and to provide the govern Corp., Ansul Chemical Co., The ment with the specifications for pro Dow Chemical C o., and Monsanto curing the herbicides they were for C o.--o f the " need right now o f mulating. There was " lack o f the use chemicals that will do the job at an o f military specifications for [her earlier time, and in a quicker bicide] procurement actions" until period." General Delmore specifical 1967 when a coordinated military ly charged the companies present with specification was drawn from infor the " p a rtic u la r o b jectiv e" of mation supplied by the war contrac " mak[ing] sure it [the herbicide to be tors. developed] is perfectly innocuous to In M arch. 1968, while the govern man and animals and at the same ment was attempting to finish the time, will do its jo b ." fashioning of a coordinated military Albert Hayward, chief of the pro specification for the purchase of gram coordination office of Fort " Agent Orange," efforts were made Dietrich, said at the conference: " to resolve industry exceptions" ^ " It goes w ithout saying that the the Air Force's purchase description materials must be applicable by (not specifications), and as a result of ground and air spray, that they must those concerns, changes were made in be logistically feasible, and that they the purchase description " ...to more must be nontoxic to humans and live nearly reflect commercial practices in stock in the area affected. Not only production of O range...." should these materials be nontoxic, Military herbicide operations were but it seems to me that it is im portant carried out from 1962 to 1971. They that they not have any cosmetic ef were used primarily for 1) defolia fect. If, for example, a material had a tion of trees and plants to improve marked red fluorescence and a num observation and prevent ambush of ber of people were obviously stained friendly forces and 2) destroying by the m aterial, then our enemy food crops of hostile forces. After a might derive considerable p ro p relatively slow build-up from 1962 to aganda value from this fact even 1965, herbicide operations increased hough the individuals were not in rapidly to a peak in 1967, then de any way injured by the material. clined slightly in 1968 and 1969, drop " In a very real sense, this program ping sharply in 1970, and eventually in defoliation is a little bit unique stopping in 1971. Defense estimated with respect to the usual military-in that approxim ately 17.7 m illion gallons of herbicides were sprayed during the nine-year period. The Na tional Academy of Sciences estimated that of the 3.6 million acres sprayed, 66 percent were sprayed once, 22 per cent twice, eight percent three or more times, and four percent four or more times. Converting the millions of gallons sprayed to pounds of herbicide, the 44 million pounds of 2,4,5-T con tained an estimated 368 pounds of the toxic contam inant 2,3,7,8-tetrachloro dibenzo P-dioxin (TCDD or dioxin). The National Academy of Sciences estimated that between 220 and 368 pounds o f TCDD were re leased over South Vietnam during the period August 1965 to February 1971. j Termination of Herbicide Use The decision on April 15, 1970 leading to the termination of all mili tary herbicide use was caused by a fascinating interplay of diverse elements of our political fabric-- scientific, regulatory, diplomatic, and legislative. These included the Na tional Academy of Sciences (NAS), the National Cancer Institute (NCI), the National Institutes of Health (NIH), the American Association for the Advancement of Science (AAAS), a spate of independent scientists, a host of executive departments and agencies, the Departments of State, Defense, Agriculture, Interior, and Health, Education, and Welfare (HEW) (now Health and Human Ser vices), the Air Force, the Surgeon General, the Office of the President, and Congress itself. One of the first o f many distinguished scientists to voice con cern over the continued use of her bicides containing the toxic substance dioxin was Yale botanist A rthur W. Galston, at the time president-elect of the Botanical Society o f America. In a 1967 article in the New Republic, professor Galston warned of the potential hazards of continued un bridled use of herbicides that was all too prophetic: " We are too ignorant of the in terplay of forces in ecological prob lems to know how far-reaching and how lasting will be the changes in ecology brought about by the wide spread spraying of herbicides in Viet nam. These changes may include im mediate harm to people in sprayed areas...." The DOD was not unmindful of 3923 V -H oz-l i the growing criticism within the scien In September 1968, the State committee had seen the BRC report tific com m unity of the departm ent's Department released an assessment of (June or July 1969), the first reports f use o f herbicides in Vietnam. Each the ecological consequences of the of human birth defects allegedly at year the justification for continuation defoliation program in South Viet tributed to the Herbicide Orange ap of O peration Ranch Hand was re nam. Tschirley, a plant ecologist, peared in Vietnamese newspapers. viewed. In 1967, DOD contracted visited South Vietnam for one month They blamed the increases on the with Midwest Research Institute and later published the results of his chemicals used in defoliation. There (M RI) of Kansas City, Missouri, for observations in Science, the journal is still no scientific agreement regard an in-depth assessment of the ecolog of the AAAS, concluding: ing interpretation of these essentially ical effects o f extensive or repeated " The defoliation has caused eco- anecdotal findings. use of herbicides. MRI concluded logic change, not irreversible, but re Mounting national concern about that the greatest short-term or long covery will take a long tim e.... The 2,4,5-T took on a greater sense of term ecological consequence' [in effect on animals is now unknown, urgency when, in October 1969, Dr. South Vietnam] was the " destruction but it does not appear to have been Lee F. Dubridge, science adviser to of the vegetation...," the long-term extrem e.... There is no evidence to the President, announced that there effects on wildlife were unpredictable suggest that the herbicide used in would be a partial curtailment of the (some good, some bad), " the her Vietnam will cause toxicity for man use of this herbicide. Following this bicides used [in South Vietnam]...Will or anim als...." * announcement by the Office of the not persist in the soil for a long period Responsibility in Science sponsored President, the DOD restricted the use o f tim e ..." and, finally, " ...the a visit by two zoologists in March of Herbicide Orange to areas remote possibility o f lethal toxicity to 1969. Orians and Pfieffer published from population in South Vietnam. h u m a n s...is highly unlikely and their report in 1970...." * An NIH report that 2,4,5-T could should not be a matter of deep con In a February 1969 meeting of the cause malformations and stillbirths in c e rn ...." N A S /N ational Research Council mice prom pted these actions. Both NAS and AAAS reviewed the Committee, a " confidential" report In all probability, the " leaking" to report following its publication in prepared by the Bionetics Research the press o f the USDA report December 1967 and felt that although Council (BRC) Committee (which the (allegedly by a member of " Nader's it was a creditable review of the USDA had employed to study the Raiders," who "suggested" that the available scientific literature relating m u ta g e n ic , c a rc in o g e n ic , a n d USDA was trying to " hide" the ad to herbicides and the ecological ef teratogenic potential of 140 common verse report) prompted the Surgeon fects, m ost o f it supported by the ly used pesticides) was distributed in General o f the United States to issue, chemical companies which manufac dicating a " significant potential [for on April 15,1970, an opinion that the tured the herbicides, it was only a 2,4,5-T] to increase birth defects." use of 2,4,5-T might be hazardous to first step in such an investigation. About four months after the NAS " our health." DOES YOUR CLIENT HORSE AROUND? Whether your client rides horses, breeds them or races them, whether he has one horse or 100, you need: " LAW FOB THE HOBSE BBEEDEB" By: Kenneth A. Wood, B .& , J.D . ...in your library, which covers virtually evqry area you will encounter in handling your clients horse matters: Legal Considerations In Entering The Horse Business Insurance Federal Income Tax Liabilities of The Horseman Syndication Leasing Contracts Purchases and Sales of Horses Training Contracts Federal Laws & The Horse Industry Data The initial cost is $39.50 which provides the purchaser with the approximately 700 page book which will be kept current for one full year by periodic supplements at no additional cost. Presently the cost to maintain the subscription after the one year period is $25.00 per year. " Law for The Horse Breeder" is $39.50 plus $2.50 for shipping and handling charge. California residents please add $.90 sales tax. " Law For The Horse Breeder" is the only publication of its kind - order yours today. Send your check or money order to: WOOD PUBLICATIONS P.O. Box 963 " Y Rancho Santa Fe, California 92067 714/756-3382 DQOA C^ / ^/O On April 5, 1970 the Secretaries 01 (of drug and chemical registration) as Agriculture, HEW, and the Interior scientifically unattainable. Future jointly announced the suspension of registrations were to be granted on certain uses of 2,4,5-T. The suspen the basis of either " Negligible Resi sion resulted from published studies due" or "Permissible Residue." In indicating that 2,4,5-T was a tera dustry was given until December 31, togen. On the same day, the DOD 1967 to comply by obtaining toler suspended all use of Herbicide ances for residues of 2,4,5-T in all O range. Dow, the primary m anufac treated food, feed products, and by turer o f 2,4,5-T and 2,4-D , stated products. On May 1, 1970, the EPA that according to its tests (with cancelled (among other uses) all 2.4.5 - T that had been produced in ac 2,4,5-T uses on food crops intended cordance with production specifica for human consumption. tions) there was no indication of any Dow and Hercules, Inc. petitioned fetal abnormalities. However, the to refer the cancellation to an advis Dow tests did confirm the BRC find ory committee of scientists to review ings that when dioxin was present in all relevant facts. The advisory com quantities exceeding (then-current) mittee met and submitted its report in p ro d u c tio n sp ecificatio n s, birth May 1971, recommending: " permit defects did occur. ted use of 2,4,5-T on forests, range land and rights-of-way providing that Civilian Use of 2,4,5-T the limit of 0.1 ppm contamination with TCDD be set for all future pro The herbicide 2,4,5-T has been duction of 2,4,5-T; that all 2,4,5-T marketed as a " registered pesticide" be applied no more than once a year in the United States since 1948. The at any one site; and that 2,4,5-T be USDA reported that principal domes tic use in 1974 was for weed control on rights-of-way, range land and pastures, rice crops, and forests. Since 1950 most of the chemical in dustry has known that large quan tities o f TCDD may be formed as a by-product of the 2,4,5-T manufac turing process if the manufacturing procedures were not carefully con trolled. At one time, 2,4,5-T which In addition to the ex posures of American and Australian ser contained between 30-40 ppm of TCDD was produced. After concern arose in 1969 about the extremely tox vicemen in Southeast Asia, there are also oc ic effects o f TCDD, manufacturing cupational accidents.... methods were changed, and by 1971 industry had reduced TCDD content in commercial samples to less than 1 ppm. Current US manufacturing specifications require 2,4,5-T pres ently being sold to contain less than 0.1 ppm , and several foreign coun applied with proper caution so that it tries now p ro d u ce com m ercial will not contaminate other areas 2.4.5- T containing less than 0.05 where it may come into contact with ppm of TCDD. hum ans." Herbicide 2,4,5-T has been the The USDA published a Pesticide subject of a number of federal regula Registration (PR) Notice on Septem tory actions following its first regis ber 28, 1970 advising o f the presence tration in M arch 1948. Initially, regu o f chlorodioxin contaminants (such lation o f 2 ,4,5-T came under the as TCDD) in economic poisons (in aegis of the USDA. Subsequently this cluding herbicides and pesticides). It function was transferred to the Envir stated further that such contaminants onmental Protection Agency (EPA). in 2,4,5-T constituted a possible On April 13, 1966 the USDA and the hazard to people since they had been "ood and Drug A dm inistration found to be extremely toxic to tFDA) jointly announced in the Fed laboratory animals. This PR advised eral Register the abolition of the " no that appropriate regulatory action residue and zero tolerance" concepts would be taken under the Federal In secticide, Fungicide and Rodenticide Act (F1FRA) because products con taining chlorodioxins were considered to be " in violation of FIFR A ." Dow promptly moved to protect one of its major markets, rice, and filed for injunctive relief in the district court in Arkansas, an area heavily involved in rice crop produc tion. An injunction was granted in July 1972, enjoining further adm inis trative action against 2,4,5-T. The US court of appeals for the Eighth Circuit overturned this injunction in April 1973, and the EPA proceeded with formal cancellation hearings to remove the herbicide from the market. (Dow was not the complete loser in this action: It had been suc cessful in gaining nearly two years of delay in the suspension o f the appeal.) Extensive public hearings were held during 1974 on all uses o f 2,4,5-T , in cluding insecticides as well as her bicides containing 2,4,5-T. In June 1974, the EPA decided that it would " continue its TCDD residue m onitor ing" since it did not have sufficient hard evidence needed to rebut the herbicide's m anufacturers and users (farm groups), and (to the shock of environmental groups) withdrew the proceedings. Background of Dioxins The " dioxin" o f today's media ac counts usually refers to the 2,3,7,8-tetrachloro isomer of p-dibenzo dioxin (TCDD). It has been called the most lethal synthetic chemi cal known to m an, but it is only one of a group of related aromatic, tricyclic compounds. The num ber o f chlorine atoms in the chlorinated dioxins may vary from one to eight, and more than 221 different isomeric forms of the polychlorinated dibenzo-p-dioxins (PCDDs) are pos sible. Because of their toxicity, few of the chlorinated dioxins have been synthesized so far and studied for their chemical and physical prop erties, and only the isomer with chlorines at the 2,3,7,8 position (2,3,7,8-tetrachloro dibenzo p-dioxin, the " dioxin" of the " Agent O range" case) has even begun to be examined m detail for its toxico logical effects. Although the first chlorinated dioxin, the octa-isomer, was prepared as early as 1872 in Germany, its struc- LO CM CO CO lure did not become clear until 1957, Dow scientists seem to have been the products made from TC P, such as when the details of its synthesis were first to establish the extraordinary 2.4.5- T. with the rabbit ear skin test published together with that of a toxicity of TCDD. for the toxic acnegenic agent. On the related compound, tetrabromo diben- The toxic effects of TCDD. alone basis of such precautions, Dow as /o dioxin. In both cases the labora or in conjunction with TCP: 2.4.5-T; serted in a 1964 press release that its tory workers were hospitalized. In the and related chlorophenoxv com 2.4.5- T was absolutely nontoxic to laboratory, the synthesis had been ac pounds. have been observed under a humans or animals. By 1965, Dow complished by halogenating (adding wide range of conditions and cir confirmed that the toxic contaminant chlorine and bromine respectively) cumstances. In addition to the ex was TCDD, and developed a gas the dioxins. However, the chlorinated posures of American and Australian chromatographic technique sensitive dioxins can also occur during servicemen in Southeast Asia, there to 1 ppm of TCDD in TCP or pyrolysis of 2,4-dichlorophenol and are also occupational accidents: ex 2.4.5- T. Dow admitted that it treated 2 .4 .5 - Trichlorophenoi (TCP) and posures from handling contaminated a negative skin test as evidence of the certain phenoxy herbicides such as intermediates, such as TCP; ex absence of TCDD, while recognizing 2 .4 .5 - trichloro phenoxyacetic acid posures from a g ric u ltu ra l and the insensitivity of the test concentra (2,4,5-T) made from TCP. silvicultural applications; and ex tions of TCDD below the 1 ppm level. C o n te m p o ra n e o u sly with the posures of individuals to contam Dow also admitted that it had laboratory syntheses of the chlori inated products in the community. failed to inform either the USDA or nated dioxins, chloracne was ob The symptomatology and effects in the DOD of its findings o f dioxin- served among chemical plant workers duced by TCDD reflect a wide range contaminated 2,4,5-T. It should be exposed to certain chlorinated chemi of factors including dosage and dura stressed that the USDA relied ex cals (perchlorinated naphthalenes). In tion of exposure, presence of other clusively on toxicological information the 1940s chemists at the Boehringer toxic chemicals, and the age, sex, and provided by registrants of pesticides, Com pany in Hamburg, Germany, reproductive status of the exposed. and was not in the practice of con tested a number of chlorinated com TCDD is peculiar among highly ducting its own research or even pounds that could be possible causes toxic chemicals in that death is monitoring the published literature. o f chloracne and established that delayed for several weeks after ex dibenzofurans (compounds similar to posure in many animal species, in Dioxin Toxicology the dioxins) were active in the rabbit cluding human beings. Although the ear bioassay developed by Dow to actual cause of death in some animal The chlorinated dioxins are potent protect its own workers. When species can be established, in many inducers of the hepatic and renal Sanderman synthesized 20 grams of species the actual cause o f death is microsomal enzymes which are re TCDD in studies of chlorophenols as not apparent upon autopsy or even sponsible for metabolizing foreign wood preservatives, his laboratory microscopic examination of the tis compounds and steroid hormones. assistant required hospital admission sues. The specific mechanism by Unlike other stimulators of mixed after developing hyperkeratosis and which TCDD causes death in human function oxidases, dioxin stimulates chloracne. Schultz at Boehringer ap beings is not yet known. not just one enzyme in a single tissue, plied a small spot of TCDD on his Preliminary prim ate studies suggest but a broad range of these enzymes in arm and developed the lesions which, that the effects o f TCDD exposure a variety of tissues. The chlorinated upon biopsy, were typical of chlorac are cumulative and that the lethal dioxins also interfere with the syn ne. These findings, however, were not dose is similar regardless of the time thesis o f the porphyrin compounds published in the general scientific span over which it accumulates. The such as cytochrones and heme which literature until 1957. implications of this phenomenon are are necessary for all oxygen transfer Sorge, a chemist at Boehringer, that the effects o f dioxin exposure are reactions in the body. TCDD is also discovered that the formation o f cumulative--a dangerous property it embryotoxic and teratogenic. The TCDD depended on the temperature shares with such well-established c h lo rin a te d d io x in s a re a lso of the chemical reaction and de veloped a low temperature procedure for the synthesis of 2,4,5-T in a closed system. The Boehringer prod uct became more expensive to m anu hazards as ionizing radiation. Such a cumulative effect is most likely at tributable to " tissue imprint" irrever sible effects remaining after the TCDD molecule has left the active mutagenic in certain test systems, and inhibition o f mitosis and chrom o <X> somal abnormalities have also observed in certain organisms. been CM co Intercalation within DNA is be c o facture but less dangerous to handle. sites in a cell. M any other toxic ef lieved to be a possible mechanism Although Boehringer informed other fects, both acute and chronic, have responsible for the mutagenicity and producers of the hazards of the high been observed in hum an beings and in perhaps the carcinogenicity of the temperature method of TCP m anu other animal species. PCDDs. Their carcinogenicity also facture and in 1957 made the tech In April 1970 Senate hearings be may be related to changes in nology available to avoid these fore Senator H art, Julius Johnson, a m icrosom al enzyme m etabolism hazards, it was only the occurrence of vice-president of Dow, stated that his modifying the ability of cells to react 5. serious outbreaks of chloracne that company had been aware since 1950 to other carcinogens or to be pro finally forced some of the American of the possibility that highly toxic tected from the direct effects of a chemical companies to discontinue acnegenic impurities were formed in primary toxicant. their high tem perature production TC P, when the Germ ans first " isola The NCI, the National Toxicology procedures and adopt the Boehringer ted the dioxin" as the contaminant. Program , and the International technique. At about the same time, Since then Dow claimed to monitor Agency for Research on Cancer of the World Health Organization all recognize the carcinogenicity of TCDD, at least in rats and mice. The animal experiment results have some similarity to the effects of ionizing radiation in that there is little organ specificity among the cancers in duced. Because of the multiplicity of tumors which nave been observed, it is also theorized that at low doses TCDD may be a potent promoter of carcinogenesis by other toxicants through diverse biochemical, molec ular, and physiological mechanisms. Human Exposures to Dioxin Since 1949, there has been a series of sudden occupational exposures as a result o f accidents in eight different plants involved in the m anufacture of TCP. These provided early warnings as to the serious toxic effects of the TCP impurities which were later iden tified as dioxins, particularly TCDD and the related dibenzofurans. From 1949, there also were a num ber of incidents of occupational disease involving workers handling TCP; 2,4,5-T, or related compounds contaminated with dioxins, particu larly TCDD and the related dibenzo furans. Typically, the symptoms ap pearing after an acute exposure began with a burning sensation in the eyes, nose, and th ro at followed by headache, dizziness, nausea, and vomiting accom panied in some cases by diarrhea and abdom inal pain. Some days later exposed individuals report itching, redness, swelling of the face, often over the eyelids, nose, and lips, sometimes accompanied by mucus membrane inflammation and hemorrhage. Hemorrhagic cystitis (bladder), pleuritis, pyelonephritis blepharo-conjunctivitis, and other membrane inflam m ation o f the eyes have also been reported by some vic tims. A few weeks to several months after the exposure the onset o f chloracne has been observed. Chioracne, however, is not a necessary symptom of TCDD or TCDF toxicity. Peri pheral neuropathy and liver abnor malities following exposure to TCDD have been seen in people with no history of chioracne. Since most of the cases which have been reported in he medical literature were those referred to dermatologists because of chioracne, cases without obvious chioracne symptoms frequently have been overlooked. Chioracne is characterized by in flamed nodules and pustules on the face, forearms, shoulders, neck, trunk, feet and legs, leading to the formation of comedones (black heads) and cysts. It takes one to two months for this eruption to ap pear as typical chioracne with hyper pigmentation of the skin in patches where the comedones, cysts, and pustules are present. Rupture of the pustules frequently releases a foul smelling (rancid) fatty material. The eruption itself may be quite disfigur ing and often dismissed as nothing more than a " late case" of the " ter minal acne" of adolescence. Chioracne has protean manifesta tions ranging from chronic pustular cystic, follicular, acneiform , hyperkeratosis, and blepharocon junctivitis, to milder reversible forms with minimal residual scarring, pit ting, hyperpigmentation, depigmen tation, and hypertrichosis. The chioracne is generally, but not in variably, associated with a wide range of other symptoms of multi-system disease. Chioracne has been recognized in TCP; 2,4,5-T, or other chlorophenoxy-exposed workers, and in those involved in plant accidents with T C P or related chlorophenoxy compound. It must be appreciated that acnei form dermatitis or chioracne has been recognized as an occupational derma tosis since the 1870s, and as such has not unnaturally attracted the profes sional interest of dermatologists. The possibility has to be considered that this has introduced an understand able bias in favor of overemphasis on the dermatological aspects of TCDD poisoning, and may be responsible for the failure to adequately recog nize and report systemic effects in the absence of overt dermatological manifestations. Systemic disease in the absence of chioracne has, however, been reported. Multi-system Disease TCDD is well recognized in the clinical and toxicological literature as a potent multi-system toxicant pro ducing a panoply of acute and de layed effects. Recognized clinical symptoms include asthenia, muscular weakness, pains in limbs and joints, insomnia, photosensitivity, nausea, vomiting, and diarrhea. Laboratory findings include abnormalities in liver funcin, porphyria, peripheral neuro- paihv. elevated triglycerides and cho lesterol. Psychological and personal ity changes have been observed, as well as an excess o f deaths from cor onary disease among a Dutch TCP accident clean-up crew. This multi system disease complex is generally consistent with that recognized in pre liminary surveys of Vietnam veterans, although no large-scale analysis has yet been published. Residual chioracne or chloracneiform lesions are commonly seen in veterans, and include cystic pustules, clusters of comedones, hyperpigmentation, depigmentation, acneiform pits, and skin and eye photosensitivity. A history of alcohol intolerance is not uncommon and ap pears suggestive o f liver dysfunction. Within one or two months after the exposure, although the period may be as long as two years, and in some cases without any clinically manifest chioracne, other symptoms may ap pear, including aching muscles, main ly in the thighs, legs, and chest, with aggravation on exertion; aching joints have been reported without swelling. Fatigue, irritability, insom nia, and marked decrease in libido are also w ell-established sym ptom s among dioxin victims. These symp toms may continue for years after the exposure. Abnormal nerve conduc tion velocity may be present and can be detected in the sensory nerves when the condition is mild, and both sensory and m otor nerves in more ex tensive neuropathies. The relation ship of the pain to the neuropathic condition has not yet been clearly defined. Hepatic dy sfu n ctio n is o ften observed and is one o f the symptoms common to many of the plaintiff veterans in the " Agent O range" litigation. It may be asymptomatic, or it may contribute to the general fatigue of the victim. The clinical relationship has not been clarified. Manifest porphyria cutanea tarda with the symptoms of hirsutism, in creased skin pigmentation, and blister formation aggravated by sun expo sure is relatively uncom m on, al though disturbances in porphyrin metabolism can often be detected on laboratory urinalysis. Increased serum lipids, triglycerides, and cholesterol with accelerated coronary ^ atheroschlerosis and premature death ^ from ischemic myocardial disease ( have also been reported after ex- ( \ posure to TCDDt 3927 Hellm ann, p.21 ' Waggaman v. Forstmann, 3807 D C. Cl. App.. 21' V2d 310 n.l: Fed. R. Evtd. T02 (197?). ' Id.at 217 A .2d 310. n.4. 1 Dalmo Sales o f Wheaton, Inc. v. Steinberg, 407 A.2d 339 (I9'9) n.4. * Reed v. State. 9 BALT. L. REV. 146. 160 (Fall 19791. Reed v. State. 391 A.2d 364. 422 (1978). Yannacone, Kavenagh, Searcy, p.30 ' This article has been adopted from facts alleged in the original class action complaint of the Vietnam combat veterans Filed on behalf of ihe late Paul Reutershan in January 1979. much of which has been detailed in ihe investigations of retired Col. Bruce F. Meyers, U .S.M.C., former Regimental Commander of the 26th Marine Regiment ai Khesanh in 1968. and at present associate dean of the Univer sity of Puget Sound Law School. (See, Soldier o f Orange: The Administrative, Diplomatic. Legislative and Litigatorv Impact o f Her bicide Agent Orange in South Vietnam, 8 BOSTON COLLEGE ENVIRONMENTAL AFFAIRS LAW REVIEW 159-178 (1979).) Addi tional information came from (he direct testimony of Dr. Susan M. Daum in the matter of Shoecraft, et at. v. Dow, which was settled in March 1981 for more than SI million, and the testimony of Dr. Samuel S. Epstein before the subcommittee on medical facilities and benefits of the Committee on Veterans' Affairs of the US House of Representatives. * G .H . Pfeiffer and E.W. Orians. MILITARY USE OF HERBICIDES IN VIETNAM. New York: Free Press (1972), pp. 117-176. 3 Tschirley. RESPONSES OF TROPICAL AND SUBTROPICAL WOODY PLANTS TO CHEMICAL TREATMENT. Res. Rept. Ars. USDA. ARPA Order No. 424. Adv. Res. Proj. Agency USDD CR-13-67. p. 197. M otley, M iddleton, p.38 ' Letter from Anonymous Author to Thomas F. Mancuso in T. Mancuso, HELP FOR THE WORKING WOUNDED 27 (1976). 3 See. e.g.. Comment Asbestos Litigation: The Dust Has Yet To Settle, VII FORDHAM URBAN LAW JOURNAL, 55 (1978); Smith and Berek, Sailing the Uncharted Seas o f Asbestos Litigation Under the Longshoreman's and Harbor Worker's Compensation Act, 22 WILLIAM AND MARY LAW REVIEW 177 (1980); Motley, Filing Overlooked Claimsfo r Occupational Diseases. 13 TRIAL 36 (1977); Sweeney. The Asbestosis Time Bomb, 14 TRIAL 10 (1978), p. 17; Motley, Proving the Cancer Connection in the Courtroom, 15 TRIAL 3 (1979). p. 40; Henderson, Product Liability Disease Litigation: Blueprint fo r Occupational Safety and Health, 16 TRIAL 4 (1980), p. 25; Motley, The Lid Comes O ff, 16 TRIAL 4 (1980), p. 21; Mehaffey, Asbestos Related Lung Disease, 16 THE FORUM 341 (1980); Elser, Asbestosis: Its Impact Upon Products Liability and W orkmen's Compensation, 1975 INSURANCE LAW JOURNAL 459. * It is estimated that 67,000 persons will die of cancer during the next 30-35 years as a result o f exposure to asbestos. Indeed, the asbestos disease problem has been properly characterized as epidemic in scope. NATIONAL CANCER INSTITUTE AN D NATIONAL IN STITUTE OF ENVIRONMENTAL HEALTH SCIENCES, ESTIMATES OF THE FRACTION OF CANCER INCIDENCE IN THE UNITED STATES ATTRIBUTABLE TO OCCUPATIONAL FACTORS (Draft Summary September II, 1978). According to estimates made by the US Department o f Health, Education, and Welfare (now the Department o f Health and Human Services), between 8 and 11 million workers have been exposed to asbestos in the US since the beginning o f World War II. O f that total, approximately 1.5 to 2.5 million are presently employed, while the remainder--between 6.5 and 8.5 million workers--were formerly employed in environments with significant asbestos exposure, including 4.5 million who worked in shipyards during World War II. Of these workers, approximately 4 million are believed to have had heavy exposure to asbestos. Based on epidemiological studies o f workers, it is estimated that 20-25 per cent o f heavily exposed workers die o f lung cancer, 7-10 percent of pleural or peritoneal mesothelioma, and 8-9 percent of gastrointestinal cancers. These figures are probably underestimates o f lifetime risks because relatively few workers have yet been fol lowed to the end o f their normal lifespan. The total fraction o f heavily exposed workers likely to die o f these cancers is probably between 35-44 percent. O f the 4 million heavily exposed workers, approximately 1.6 million are thus expected to die o f asbestos-related cancers. Assuming that the excess risk to the 4-7 million less heavily exposed workers is one-quarter o f that to the heavily exposed workers, the total numer o f cancers associated with asbestos in the less heavily exposed group would be expected to be about 0.55 million, raising the total to about 2.15 million. Id. at 1-2. 4 Catt, Cancer P eril P robed in C ity Conrail Shops, READING TIMES (Pa.), June 1, 1981, at 1, col. 4, citing, NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AN D HEALTH INTERIM REPORT OF HEALTH HAZARD EVACUATION CONSOLIDATED RAILROAD CORPORATION, H H E-81-028 (February 1981). * Supra note 1, at 29. * Catt, supra note 4, at 8, col. 5. ' Abrams, A sbestos Exposure M ay Be Tied to Three Deaths, READING (Pa.) EAGLE, June 1, 1981, at 2, col. 2. * For an outstanding text on asbestos disease offerina a fuller explication of these differences, see Selikoff and Lee, ASBESTOS AND DISEASE, Academic Press (1978), 33-50. * Id. at 16-20. Also see. BoreI v. Fibreboard Paper 'ducts Corp., 493 F.2d 1076, 1083 N.3 (5th Cir. 1973). 10 Selikoff and Lee, id., at 177. A full explication of in, precise effects of asbestos upon the respiratory system is beyond the scope of this paper. The reader is generally referred to the Selikoff and Lee textbook from which most o f the instant text was distilled. " Selikoff and Hammond, Asbestos Associated Disease in the United States Shipyards, 28CA-A CANCER JOURNAL FOR CLINI CIANS 37 (1978). 13 Selikoff and Lee. supra note 8, 198-206. There exists an interesting scientific dispute regarding the significance of pleural asbestosis. Many contend that changes in the pleura are nonspecific or, if asbesios-induced. are merely benign markers indicative of prior asbestos exposure. Others contend that the pleural changes may be harbingers of cancer or may themselves impair the lung. It is of interest that in August 1981. a jury in Duval County. Florida circuit court (Jacksonville) awarded Edward Janssens and his wife a total of SI .857 million in actual and punitive damages in what was essentially a pleural asbestosis case. Other juries have been totally unpersuaded that the con dition is disabling. 15 Selikoff and Hammond, supra note 11; Selikoff and Lee, supra note 8. at 307-336. Cancers of the kidney, pancreas, and buccal cavity may also be increased among asbestos workers. '* Lewinsohn, H .C.. Health Hazards O f Asbestos: A Review O f Recent Trends. J. SOC. OCCUP. MED. 24:2 (1974). '5 For an excellent discussion of the relative risks of asbestos and cigarettes in lung cancer causation, .see CHEST, August 1980 (special sup- A. 3929  t a b 'G oeee 2/ i S C IEN C ES The Weekly Newsmagazine of Science A Science Service Publication Volume 141, No. 2, January 11.1992 Alfred Scott McLaren Patrick Young Laurie Jackson Vaughan Janice Rlckerlch Janet Raloff Bruce Bower Elizabeth Pennisi Richard Monastersky Ron Cowen Carol Ezzell, Kathy A. Fackelmann Ivars Peterson Larry Norland Karen Schmidt Liz Marshall Donald R. 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This Week 20 Radio Pulses Hint at Unseen Planets 20 W itnessing the birth of a radio supernova 21 School memories endure as time goes by 22 Family ties heighten risk of enlarged heart 22 Ancient quakes signal future Northwest risk 23 Neural-net neighbors learn from each other 23 Planes: Larger role in global warming? 23 CF gene therapy on horizon Research Notes 28 Biology 28 Biomedicine 30 Physics 30 Science & Society Articles 24 Dioxin's Other Face Cover: During the Vietnam war. the U.S. military sprayed millions of gallons of Agent Orange defoliant over the southeast Asian countryside and dioxin became a persistent part of that environment and its food chain. The Vietnamese are now among the most heavily exposed people on Earth. Breast-feeding infants receive particularly high doses of dioxin, which concentrates in human milk. (Photo: Arnold J. Schecter) Departments 19 Letters 31 Books Science Service, a nonprofit corporation founded in 1921, gratefully accepts tax-deductible contributions and bequests to assist its efforts to increase science and mathematics literacy among the young and minorities, and to advance the public understanding of science in general. Board of Trustees--Chairman, Glenn T. Seaborg; Vice Chairman, Gerald F. Tape; Treasurer, Willis Harlow Shapley; Joseph W. Berg Jr.; Robert W. Fri; David A. Goslin; J. David Hann; Leon M. Lederman; Shirley M. Malcom; Elena O. Nightingale; Ben Patrusky; H. Guyford Stever; Sanford J. Ungar; Deborah R Wolfe. Honorary Trustees -- Edward Bliss Jr.; Bowen C. Dees; O.W. Riegel; John Troan. President: Alfred Scott McLaren; Vice President and Business Manager: Donald R. Harless. Letters Radiation: Risks and regs No one denies that hazardous radioactive wastes need to be treated with respect. But the mere tag "radioactive" does not indicate that a substance is hazardous. Naturally occurring radioactive material (NORM) is in the envi ronment around us each day ( "NORM: The New Hot Wastes," SN: 10/26/91, p.264). Human beings evolved in the presence of such radio activity. Indeed, there is evidence that too little radiation can adversely affect human health, just as too much can. One of the tenets of science is to measure before forming opinions. Your article is woefully lacking in measurements. Example: "The NORM-tainted fencing and soccer goal post here emit low but measurable levels of radiation." My body "emits low but measurable levels of radiation." So do the bricks in homes. What are the levels? That's a key fact necessary tounderstand the situation. Another tenet of science: Compare measure- JA N U A R Y 11 1QQ9 ments to what you know. How about listing the radiation received in a year of playing soccer on that "tainted" field, compared with: a year of living in Denver (cosm ic radiation, plus uranium/thorium in rocks): a year of living in eastern Pennsylvania (ground radon); a year of sleeping with on e's spouse (carbon-14 de cay): a year downwind of a coal-fired power plant (multiple radionuclides in ash); and a year working as an X-ray technician. Given those data, your readers can decide whether NORM justifies "a comprehensive federal policy with supporting regulation." Stephen Fleming Franklin, Tenn. We never meant to suggest that soccer goalposts emitting "measurable" radiation represent a hazard to young athletes. Indeed, as we noted-in the article, the State o f Louisiana has deemed that such recycled pipes don't constitute a health hazard--so long as their ends are sealed shut to prevent the inhalation o f any scaly particles that come loose. The pipe essentially shields the public, so that externally measured radiation typically runs only to 25 to 50 microrems per hour (pr/hr). However, inhalation o f the scale inside such pipes --emitting hundreds of thousands o f pr/h r--could pose a hazard. And according to L. Hall Bohlinger o f Louisiana's Department o f Environmental Quality, "even at [external read ings of] 25 pr/hr, [the radiation associated with thatpipe scale] is much higher than you'd want to fall out on the ground." Yourcomments on comparing NORM-contam- inated pipes with other ubiquitous sources o f low-level radiation appear to miss the point o f the regulators quoted in our article. The regula tors did not conclude that very low levels o f radioactivity necessarily pose a health threat. Rather, theyargued that it's inconsistent to let one industry treat its NORM-tainted wastes like com mon commercial refuse while requiring another industry (e.g., electric utilities) to pay the high costs o f monitoring and managing similarly low- level wastes as federally regulated "radioactive wastes."The state officials merely ask for unifor mity in the regulations and legal liabilities borne by all industries generating low-level wastes. 3931p - J. Raloff 19 Dioxin's Other Face Portrait of an "environmental hormone1 parti' On B irn l dtoocsae very sure heal diiii By KAREN F. SCHMIDT 1 ble rea: ln i in W hen a villain starts looking like a friend, it's time to look again. Take TCDD, the most notorious and potent member of the dioxin family. Once demonized as "the most toxic syn thetic chemical known to man" because of interactions. Unlike most toxicants, dioxin causes an array of biological re sponses that vary widely according to tissue. For example, TCDD may goad one cell type to reproduce wildly and cause another to deviate from its normal path tory in Research Triangle Park, N.C. A single hormone can induce an array of effects in different tissues and species, she explains. attt TC. im: als to ot of its exquisitely lethal effect on guinea pigs, TCDD now appears "no more risky than spending a week sunbathing," as a recent New York Times article put it. In 1983, scares over TCDD forced sev eral thousand residents of Times Beach, Mo., to permanently flee their tainted community But "given what we now know about this chemical's toxicity and its effects on human health, it looks as though the [Times Beach] evacuation was unnecessary," Vernon N. Houk --the sci entist at the Centers for Disease Control toward specialization. Different animal species also vary in their responsiveness to dioxin. It takes several thousand times more TCDD to kill a hamster than it does to kill a guinea pig. Yet the hardy hamster is quite susceptible to TCDD's triggering of increased cellular levels of a P450 enzyme -- a protein catalyst that plays a role in detoxifying certain chemicals within the body and rendering others more toxic. Unfortunately, epidemiologic studies have done little to resolve toxicologists' T he environmental hormone the ory also helps explain why dioxin appears to induce a variety of cancers rather than a single hallmark type --such as the rare form of cancer, called mesothelioma, that signals as bestos exposure. Unlike most carcino gens, TCDD does not directly damage DNA in a target organ, notes George W. Lucier of the National Institute of Envi ronmental Health Sciences in Research Triangle Park. However, he explains, di oxin clearly enhances abnormal cell lie ur. 26 st dr e! ir k V c r C yho originally spearheaded the evacua muddy understanding of dioxin's human growth and appears to cause cancer by tion --acknowledged, according to the hazards. For instance, such studies rarely amplifying the diverse activities of other Times article last August. turn up consistent adverse effects among carcinogens. t i Most dioxin researchers now suspect humans exposed to dioxin --with the Two recent epidemiologic studies sup that only very high doses of TCDD --as occur accidentally or in certain occupa tional settings --may increase the risk of cancer in humans. But that redefinition exception of chloracne, the disfiguring skin eruptions associated with acute TCDD exposures. Consider studies of U.S. troops poten port the human carcinogenicity of TCDD, at least at fairly high doses. In one, researchers at the National Institute for Occupational Safety and Health exam does not necessarily imply that the chem tially exposed to Agent Orange, a TCDD- ined health records for workers exposed ical is harmless at lower doses. tainted herbicide, while serving in Viet to TCDD at a dozen chemical plants. Indeed, this near-ubiquitous contami nam. An Air Force study of veterans who Overall, the 5,172 workers appeared 15 nant - a by-product of the paper, wood had participated in the Ranch Hand percent more likely to die from cancer and herbicide industries and of the incin defoliation program found indications than the general population, Marilyn A. eration of organic solvents --is gaining a that these men faced an increased -- Fingerhut and her co-workers reported in new and nasty reputation among tox though statistically insignificant --risk of the Jan. 24,1991 New England Journal of icologists: as an "environmental hor skin, genito-urinary and otopharyngeal Medicine. However, records on the 1,520 mone" that subtly disrupts normal physi cancers and a tendency to develop under workers whose exposures began at least ology in ways not completely understood. active thyroids and diabetes (SN: 3/3/84, 20 years ago --when plant dioxin levels More potent than some of the body's p.132). Another study found an increased were typically much higher than today -- natural chemical messengers, TCDD sup incidence of high blood pressure, benign showed nine times the normal rate for presses the immune system of mice at fatty tumors, sensitivity to light, and one particular cancer, soft-tissue sar least 100 times more effectively than corticosterone, a hormone known for that effect, dioxin researchers say. In fact, increasing evidence suggests that TCDD's depression among these veterans and miscarriages among their wives (SN: 11/19/88, p.325). A third study found that Vietnam veterans suffer higher-than-nor- coma. A similar study of 1,583 pesticide-plant workers in Germany showed that, com pared with the general population, C\* co CO ability to mess with the immune system -- mal rates of non-Hodgkins lymphoma, a TCDD-exposed workers experienced a 24 not its carcinogenicity --may represent deadly cancer of the lymph nodes, but it percent higher rate of death from all its greatest threat to public health. failed to tie the disease to Agent Orange cancers. Among workers with more than exposure (SN: 4/14/90, p.236). 20 years'exposure, the cancer death rate "If you think of TCDD as a hormone, it increased to 87 percent above normal, A ll this flip-flopping on the chemi cal's toxicity may puzzle the pub lic, but it has proved no less makes it easier to understand these very big differences," asserts Linda S. Birnbaum, director of environmental toxicol according to Alfred Manz and his co workers at the Center for Chemical Workers' Health in Hamburg. However, confusing to dioxin researchers. TCDD's ogy at the Environmental Protection they reported in the Oct. 19,1991 Lancet, toxic deeds result from a perplexing web Agency's Health Effects Research Labora the increases were not linked to any one 24 sr.iPNirtP MPW9 \/ni 141 .A of ies. hexin of ark cer, as noage W. wi re!1 di cell by her upDD, me, for msed nts. 15 cer i A. iin LOF 520 ;ast /els iy for sar- i ant amon, a 24 all han ra nal, coical ver, CET, one I particular type of cancer. preliminary unpublished data suggest On the basis of these and other studies, that immunotoxicity in mice could be Birnbaum says, "I really feel that high- occurring at TCDD doses Vs of that dose exposure to dioxin has the potential needed to boost levels of this enzyme, to cause cancer." However, she adds, "I'm she says. very concerned that much lower expo Even though scientists continue to de sure to dioxin may result in adverse bate whether an excess of this P450 health effects that are very subtie and enzyme causes any adverse health ef difficult to detect." fects, "few people will contend that sup pression of the immune system is not an adverse health effect," she observes. n an effort to update federal regula tory guidelines for human exposures to dioxin --now considered a "proba I ble human carcinogen" --EPA has begun Treassessing the scientific data on dioxin. o study TCDD's immunotoxicity, researchers generally use mice, whose immune systems model In its draft version of this document, due those of humans. In one typical test, EPA in June, EPA will focus much greater toxicologists exposed mice to TCDD, then attention on toxicological data revealing injected them with a harmless, antibody- TCDD's reproductive, developmental and stimulating agent --red blood cells from immunotoxic effects. This document will sheep. An animal's ability to produce also establish TCDD as the first pollutant antibodies serves as one useful measure to be regulated on the basis of toxicity of its immunological health. Compared observed at the cellular level. with normal mice, the TCDD-treated ani Now that most dioxin researchers be mals produced fewer antibodies to the lieve a single fundamental mechanism sheep blood cells, Birnbaum says. underlies all of TCDD's effects (see box, p. EPA researchers have also measured 26), toxicologists such as Lucier can con how well TCDD-treated mice respond to struct a unifying mathematical model to viral infections, such as influenza. Mice describe how dioxin triggers biological pretreated with dioxin readily die after effects in cells and organisms. Others, exposure to a quantity of virus that rarely including Birnbaum and Nancy 1. Ker- kills healthy mice, Gary R. Burleson of kvliet of Oregon State University in Cor EPA's Research-Triangle Park facility and vallis, will help flesh out the model by his co-workers reported in the November collecting specific data on the dose- 1990 Journal of Toxicology and Envi response relationships between TCDD ronmental Health. Birnbaum's team is and its array of biological effects. now trying to determine the dose-re "Dioxin is no more and no less potent sponse relationships of these immuno than it ever was," Kerkvliet says. "But suppressive effects. understanding the mechanism can now Because "there are so many ways to help us better estimate the human risk." cause immune suppression," Birnbaum So far, studies in mice suggest that explains, scientists can only speculate as dioxin's immunotoxic punch occurs in to how TCDD weakens immunity. Indeed, extremely low doses and may well be she notes, "there could be multiple mech more important than cancer in deter anisms." mining dioxin's primary health risk, adds At a minimum, TCDD probably inter Birnbaum. At least in animals, some feres with the normal influences of hor suppression of immunity consistently oc mones on the immune system, Kerkvliet curs at TCDD doses lower than or equal to posits. She says that it appears TCDD can those required for triggering increased combine with a particular type of recep production of a P450 enzyme -- pre tor protein inside a ceils fluid interior, viously considered a liver cell's most and then inappropriately turn on specific sensitive response. In fact, Birnbaum's genes. Some of the victimized cells may reside in glandular tissues, such as the thymus, where hormones influencing im munity are produced. Dioxin also appears to act directly on the immune system, says Kerkvliet, who studies TCDD's effects on a group of white blood cells called T-lymphocytes. She and her co-workers were initially con founded when they observed that al though TCDD boosts production of T-lymphocytes --which referee the total immune response -- it still causes an overall decline in the mouse immune system's ability to fight foreign sub stances, be they viruses or pollutants. "We think TCDD is turning on certain T-helper cells inappropriately, which then makes the overall immune response sup pressed," Kerkvliet now says. This idea fits with a new hypothesis that not all of the specialized T-lymphocytes called T-helper cells "help" strengthen the im mune response; some may actually in hibit it, she notes. For the most part, Kerkvliet believes that dioxin initiates its direct immuno toxic effects by binding to the dioxin protein receptor --perhaps in the bone marrow, where white blood cells are produced --and by toying with the nor mal functioning of genes. Recently, her research group studied how TCDD affects a mouse's production of cytotoxic T-lym phocytes, which destroy cells infected with viral invaders. The team compared responses in TCDD-treated mice with normal and de fective dioxin receptors, and found signif icantly greater immune suppression in the mice with normal receptors. They also compared the responses of these mice to a variety of polychlorinated bi phenyls (PCBs), chemical relatives of dioxin. Immunity suppression indeed correlated with each chemical's ability to bind to the protein receptor, Kerkviiet's group reported in the April 1990 Funda mental and Applied T oxicology. These findings suggest that dioxin's protein re ceptor plays an important role in its immunotoxicity, they say. During the Vietnam war, the U.S. military dumped millions of gallons o f TCDD- tainted Agent Orange over South Viet' # nam. Veterans who participated in this ^ defoliation program, called Operation ^ Ranch Hand, have experienced a variety / of health problems that might b e related A to dioxin exposure. ^ G iven the complexity of the im mune system, however, not all dioxin researchers are ready to After a single acute dose, mice with normal dioxin receptors suffered greater immune suppression than mice who had settle on a single receptor-based mecdheafective receptors. However, when mice nism to describe all of TCDD's immuno received this same amount of TCDD over suppressive effects. a two-week period, both mouse strains Michael R Holsapple of the Medical showed similar immunosuppressive re College of Virginia/Virginia Common sponses, he and his colleagues report in wealth University in Richmond has also the January 1992 Toxicology and Phar observed that "when we give dioxin to macology. Holsapple now theorizes that animals or white blood cells, we see TCDD's mechanisms may not always in problems with their immune function." volve the receptors and may differ at high However, he adds, "the immune system is and low doses. probably just a microcosm of the whole Throughout the developed world, hu complex story for dioxin." He suspects mans already experience chronic low- thatTCDD may employ different routes of dose exposures to dioxins, primarily attack depending on the conditions of through their diet (SN: 7/13/85, p.26). exposure, he says. Holsapple and his co-workers suspect For instance, his team compared the that people "exposed to low doses over effects of acute versus chronic TCDD an extended period of time (i.e. months exposures on the ability of mice to pro to years) may be at increased risk to duce antibodies to sheep red blood cells. immunotoxic effects by these chemicals through additional and presently uniden tified mechanisms." One such mechanism can be inferred from developing research in the field of endocrinology, Holsapple says. Scientists had assumed that, much like dioxin, all steroid hormones act exclusively through an intracellular protein receptor that helps it target a particular gene (SN: 8/10/91, p.85). But Holsapple points to new evidence suggesting that some ster oid hormones --including progesterone, estrogen and testosterone--can also bind to other receptors on the outside of a ceil membrane, where they can regulate the flow of salts into and out of a cell. TCDD might also tinker with a cell's physiology through such a mechanism, he suggests. Dioxin's Cellular Siege Dioxin may cause everything from immune suppression and liver tumors to cleft palate in mice, but all of these adverse effects begin with the same initial cellular changes, most dioxin toxicologists now believe. This "new" view --the impetus be hind the Environmental Protection Agency's (EPA) current reassessment of dioxin's risks --actually traces back to 1976. That year scientists reported dis covering thatTCDD--the most toxic and best studied of the 75 dioxin species -- binds with a receptor protein residing in the cells it invades. Only recently, how ever, did a group of 38 international dioxin experts unanimously conclude that every one of TCDD's myriad effects appears to begin with the compound's binding to this receptor --a mechanism resembling that of the body's own ster oid hormones. "Those biological responses [to TCDD] that have been examined in great detail have all been shown to involve this receptor," says EPA toxicologist LindaS. Birnbaum, one of the scientists who reached agreement at the dioxin conference held at Cold Spring Harbor Laboratory (N.Y.) in late 1990. She says EPA hopes to base a new assessment of human health risks from dioxin --and new regulations --on the recently rec ognized universality of this receptor in TCDD's effects. In the 15 years since scientists first realized that dioxin binds to a receptor, called aryl hydrocarbon (Ah), they have developed a detailed picture of how TCDD acts on individual cells. For example, the Ah receptor actually com prises several proteins that cluster to gether in the liquid interior of most cells in the body. Once dioxin seeps into a cell and links up with these proteins, the TCDD-protein complex can enter the cell's nucleus and cause trouble by meddling with the on-off switches of genes. Cells of some tissues, such as the liver, teem with Ah receptor proteins, while others may contain only a few. Why our cells should produce such receptors for dioxin remains a mystery. Perhaps the body produces a hor mone that normally operates through the Ah receptor, speculates Thomas A. Gasiewicz of the University of Roches ter (N.Y.) School of Medicine. As scien tists come to understand the similar and overlapping actions of our natural chemical messengers --hormones and neurotransmitters --with toxicants and drugs, traditional definitions are blur ring, he says. "Just because a compound binds to a receptor doesn't mean it's necessarily going to be toxic," Gasiewicz observes. Any natural hormone that binds to the Ah receptor probably plays a healthy role in regulating cell growth, he says. Even steroids --vitally important hor mones that act through protein recep tors--can turn "toxic" when their levels get out of whack, he adds. For instance, excess estrogen can lead to cancer. Scientists have no clues as to the identity of the hormone that normally binds to the Ah receptor, but they assume it physically resembles TCDD, for which there's a perfect docking site on one protein subunit of the Ah recep tor. Once TCDD en ters the cell, it binds with the receptor and evicts other subunits, called heat shock pro tein 90. The remaining TCDD- receptor complex must join yet another protein, however, before it can interact with genes in the cell's DNA, Gasiewicz reported in the March 19, 1991 Biochemistry. This additional protein, called the Ah recep tor transforming protein (Art), does not directly bind to TCDD, he found, but instead seems to enable the whole com plex to hook up with DNA. Gasiewicz now theorizes that Art', which may vary slightly in structure according to the tissue, might steer the complex to act on certain genes. To get at those genes, the TCDD- receptor complex must first enter the cell's nucleus. Although it's not clear just which events occur in the liquidy cytosol surrounding the nucleus, Oliver Hankinson of the University of Califor nia, Los Angeles, has found a protein that must join the complex before the ensemble can gain passage into the CO CO cell's center. This protein bears a basic CO helix-loop-helix structural motif com mon to DNA-binding proteins, Hankin son reported in the May 17,1991 Science. In fact, he told Science News, it may be the same Art protein that Gasiewicz' discovered. Although they are still identifying the receptor's protein players, Gasiewicz and Hankinson know that it takes at least two proteins and TCDD to create a I n mice, it takes far smaller quantities strong effects on the immune response." understanding of TCDD's mechanisms of of TCDD to suppress immunity than it Birnbaum is now calling for a study action, she says. d does to unleash most of TCDD's other that will determine how well TCDD-ex- Kerkvliet suspects that most Ameri >f toxic effects. And white blood cells inposed people mount an antibody re cans - who harbor about 30 parts per s both mice and humans respond similarly sponse to a novel antigen. Perhaps a new trillion (ppt) of dioxins in their blood, 11 to TCDD. But to date, there's little evi flu vaccine --one that uses an influenza including about 7 ppt ofTCDD- fall below h dence to suggest that low-dose exposures strain that hasn't previously infected hu the range of dioxin exposures that can it to TCDD suppress immunity in humans. mans --can serve the function of the jeopardize immunity. However, she adds, 1: Birnbaum, Kerkvliet and Holsapple con sheep red blood cells given to laboratory populations that commonly receive o tend that studies of dioxin-exposed hu mice, she says. higher doses, such as nursing infants (SN: r- mans have asked the wrong questions. But Kerkvliet says EPA shouldn't hold 4/26/86, p.264), chemical workers and "If Iwere to take mice and ask the same its breath waiting for the definitive epi people who consume large quantities of d [research] questions that are routinely demiologic study. It would be next to fish, could conceivably experience com a asked of the populations at Times Beach, impossible to prove beyond a doubt that promised immunity. e or in the Ranch Hand study, Iwould come dioxin causes immune suppression in "The fact that you can't clearly show 1. up with a very nebulous picture [of humans, she asserts. Unlike sheltered the effects in humans in no way lessens 's TCDD's immunotoxicity]," says Holsap laboratory mice, people come in contact the fact that dioxin is an extremely potent ple. "But when we ask different questions with many immunity-altering forces -- chemical in animals --potent in terms of [in mice], we can certainly show very such as stress, drugs and disease. Regula immunotoxicity, potent in terms of pro tors should therefore base their limits for moting cancer," says Kerkvliet. "I simply safe exposures to dioxin on animal don't believe that humans represent models and on our developing scientific some unique species." n is ))t it i:z y >e n )e ir y :r n .e e !c ll- E. >e :z ie :z it a 1 Once TCDD (T) seeps into a cell, it binds to an aryl hy drocarbon receptor (AhR) and kicks off the heat-shock protein (hsp90) subunits. The complex then joins an Ah-receptor-transforming protein (Art) and passes into the nucleus, where the ensemble binds to DNA and switches a gene on or off. Unidentified 'mystery pro teins' (?) may also participate throughout this process. An activated gene triggers production of messenger RNA (mRNA), the instructions that a cell then uses to build a specific protein, such as a P450 enzyme. Gasiewtcr complex that can on a gene. And once that complex binds to DNA, it can activate a gene and thereby cause the cell to produce excessive quantities of a certain protein. Theoretically, di oxin could also turn some genes off, which can also cause ill effects. Unlike the steroid hormones, which degrade in a few hours, TCDDmolecules require seven years to reduce their concentration by half. Because of TCDD's long half-life, it appears that the body cannot regulate this process and the gene's "switch can be turned on for inappropriately long periods of time," Gasiewicz points out. Thus, one TCDD molecule can continuously disrupt nor mal ceil physiology. In developing a model to explain dioxin's cellular actions, scientists have primarily studied how TCDD turns on a gene for a P450 enzyme. While this specific enzyme normally helps the body excrete toxic substances, it some times renders them more potent in stead. Though scientists don't know if increased levels of P450 enzymes con tribute to any of dioxin's toxic effects, they do know that the TCDD-receptor complex probably flips the P450 gene switch by a mechanism that applies to many other genes as well. "We're beginning to know the begin ning of the story, which is how the receptor activates genes," says Hankinson. "And to some degree we under stand the end product [why animals get cancer and why they die]. The real black box is which genes are turned on and how they relate to the biological effects of dioxin." Recently, William E Greenlee and his colleagues at Purdue University in West Lafayette, Ind. found several new genes targeted by the TCDD-receptor com plex. In the Oct. 18, 1991 Science, they describe identifying two dioxin-respon sive genes in human skin cells. The first directs the production of plasminogen activator inhibitor-2, a protein that func tions in embryonic development, wound healing, inflammation and can cer. The second gene contains the code enabling a cell to produce cytokine interleukin 1-beta, a protein involved in inflammation and immune responses. These are the first genetic targets of dioxin to be discovered since the P450 gene, and Greenlee says "these [new] genes are likely to play an importantrole in the toxicity of TCDD." He says they could plausibly be involved in chloracne --the hallmark skin reaction that usually signals acute human expo sure to dioxin. These findings lend credence to a unifying mechanism for all of dioxin's diverse effects, Greenlee says. "If you look at the broad range of events, it ail comes back to a very generic process," he says. Making the leap from a generic cellu lar mechanism to guidelines for human exposure --as EPA proposes to do -- could prove tricky, however. Some tox icologists argue that receptor involve ment implies a certain rate-limiting event --perhaps a minimum number of TCDD molecules needed to bind -- before a cell or animal responds with a measurable change in its physiology This in turn suggests that a "threshold" concentration may exist, below which dioxin causes little or no harm (SN: 5/18/91, p.308). However, scientists should not as sume a scde threshold exists, argues George W. Lucier of the National Insti tute of Environmental Health Sciences in Research Wangle Park, N.C. To date, his research team has found no predict able, consistent pattern in the dose- response relationships for a number of dioxin's toxic effects --nor evidence of any thresholds. "My data might not prove that a threshold doesn't exist," Lucier con cludes, "but there's also no evidence to support that one does exist." Still, which ever way the chips fall, Lucier says he's pleased that EPA is finally attempting to incorporate recent research findings into an updated view of dioxin's human toxicity. "A lot of dollars are spent doing mechanistic research," he comments. "There are thousands of papers on dioxin. We ought to be able to use some of that information in the risk assess ment process." - K. Schmidt ^0 3 ^ 3 335 cS Physics Science & Society Unraveling the details of beta decay Many radioactive atoms decay by emitting beta particles, or electrons, thereby transforming themselves into new ele ments. For each atomic isotope, these beta particles emerge from nuclei with a characteristic distribution, or spectrum, of energies. Theorist Steven E. Koonin of the California Institute of Technology in Pasadena has now shown that electrons surrounding an atomic nucleus have a discernible but hitherto overlooked effect on a given radioactive isotope's beta-decay spectrum. Reporting in the Dec. 12 N ature, he notes that this newly identified quantum-mechanical effect would typically produce a sequence of minute oscillations that slightly distort a low-energy beta-particle spectrum. The existence of this quantum effect and the "fine structure" it produces in a spectrum may have important consequences in the search for heavy neutrinos (SN: 4/27/91, p.260). Each beta decay produces not only an electron but also an invisible neutrino, and researchers have long relied on measurements of beta-decay spectra for information about the accompanying neutrinos. Koonin cautions that the presence of fine structure could change the interpretation of certain experiments de signed to search for heavy neutrinos. This characteristic spectral fingerprint may also serve as a means of gleaning information about the chemical, or elec tronic, environment surrounding an atomic nucleus, Koonin suggests. For example, he says, by precisely measuring the shape and size of the fine-structure spectrum resulting from tritium (a radioactive hydrogen isotope) embedded in a crystal, researchers could map the location of hydrogen in solids. Redpe for liquid-nitrogen SQUID SQUIDs, or superconducting quantum interference devices, are extremely sensitive, ring-shaped detectors of magnetic fields. However, the rings typically consist of materials that become superconducting only when cooled to 4.2 kelvins, the temperature of liquid helium, and this requirement limits the applications of SQUID technology. Researchers at Biomagnetic Technologies, Inc., in San Diego have now fabricated SQUIDs from ceramic copper-oxide mate rials that superconduct at 77 kelvins, the temperature of liquid nitrogen. Although several other groups have constructed such "high-temperature" SQUIDs, the Biomagnetic Technolo gies team has developed a practical manufacturing process that significantly reduces the electrical noise that interfered with the performance of earlier devices. "These [low-noise] SQUIDs are sensitive enough for many of the applications presently possible only with liquid helium devices," Mark S. Dilorio and his co-workers report in the Dec. 19/26 Nature. Switching to a laser record Ayear ago, Lester E Eastman and his collaborators at Cornell University surprised the scientific community by reporting that they had built a laser that could turn on and off 15 billion times a second (15 gigahertz). Using a tiny, newly designed and fabricated "strained quantum well" laser, the Cornell scientists have now pushed the rate up to a breathtaking 28 gigahertz, the fastest ever for any laser. Theorists had doubted that quantum well lasers would ever approach such rates. The Cornell laser consists of several extremely thin layers of indium gallium arsenide separated by gallium arsenide bar riers. These layers --no more than 40 atoms thick --serve as quantum wells, which confine electrons within their bound aries. The laser appears to owe its superior switching rate to the presence of indium atoms, which distort, or strain, the orderly gallium arsenide crystal structure. Dioxin cleanup: Status and options Dioxins--toxic by-products of waste incineration and several industrial processes involving chlorine--are nearly ubiquitous throughout the industrial world, mostly in small quantities (see story, p.24). However, some 100 waste sites in the United States alone "contain serious dioxin contamination," according to a report released last month by the congressional Office of Technology Assessment. Of the 500,000 metric tons of these wastes reported to EPA, more than 98 percent consist of tainted soil -- mostly from facilities that produced chlorophenols, chlorobenzenes and chlorophenoxyl pesticides. To date, high-temperature incineration remains the only effective technology for destroying dioxin in soil, according to the OTA report. Indeed, with properly managed incineration, "one can be assured that dioxins will be broken down" into nontoxic by-products, the report says. But this technology, requiring temperatures in excess of 1,200C, has proved expensive, currently costing an estimated $1,200 per ton of treated wastes. And even after a dioxin destruction technique has won government approval, obtaining a permit to use it at a particular waste site can take more than a year. The result, OTA notes: "Sites with dioxin-contaminated soil have been studied for a long time, but no actual cleanup work has begun." 'The OTA report highlights several promising alternatives to incineration. Base-catalyzed decomposition, for instance, uses hydrogen and temperatures of just 250C to 350C to remove dioxin's chlorine atoms --and toxicity. Price: $250 to $500 per ton of wastes. Thermal gas-phase dechlorination uses temperaturesatorabove850Ctoencouragehydrogen reactions with organic chemicals such as dioxin--probably at a cost of $350 to $500 per ton. However, OTAobserves, "In light of the relatively small number of contaminated sites, there appears to be little incentive for the private sector to [commercialize such] new technologies for destroying dioxin in soil." Women on the verge of an athletic showdown .The same year Roger Bannister ran the first 4-minute mile, Diane Leather became the first woman to run the 5-minute mile. If the two had raced against each other in 1954, Leather would have finished 320 meters behind Bannister. Today, Paula Ivan, the women's champion 1-mile runner, would finish only 180 meters behind men's champion Steve Cram. Female track athletes are improving their performances at faster rates than men and, if the trend continues, should be running marathons as fast as men by 1998, says Brian J. Whipp, a physiologist at the University of California, Los Angeles. He and UCLA co-worker Susan A. Ward predict that women will catch up with men in most track events by early next century. Whipp and Ward plotted the mean running velocity of world champion runners over the past 100years for men and the past 70years for women. They expected that improvements in mean running velocity would show signs of leveling off as athletes approached physiological limits. "To our complete surprise, we found there were no limits evident," Whipp says. Women appeared to be increasing their top speeds at twice the rate of men, the researchers report in the Jan. 2 Nature. Advances in running shoes, tracks, training and sports nutrition all contribute to faster running speeds, Whipp suspects. And an ever-expanding pool of athletes--broadening fastest among women -- heightens the chance that those genetically best suited to an event will join the race, he adds. But so far, explanations for the findings remain pure speculation, Whipp laments. He hopes physiological studies of champions will bring further enlightenment. And while he can't predict whether women will actually outrun men, he says there's no hint that their progress will slow. *eo/r- 9G6 > JOHN A. BETTS ATTORNEY AT LAW P.O. BOX 35 RAINIER, WASHINGTON 98576 Phone 206-458-7327 NOTICE OF FACSIMILIE TRANSMISSION DATE SENDER'S FILE SYMBOLS V, O o U j REFERENCE, M e m o o u Jeieg-v DOCUMENTS TO . R l C H A f t D S c A O U t G - DOCUMENTS FROM Be7rs NUMBER OF PAGES INCLUDING COVER SHEET. REMARKS: Pr3-Kto; 4-01 4-'U?3 3939 MOYER F IL E MEMORANDUM TO: RICHARD SCHULER FROM: JOHN BETTS SU BJEC T: TELEPHONE CONFERENCES WITH ATTORNEY JERRY WHITE OF F R E D E R I C T O N , NEW B R U N S W I C K , C A NA DA (506-459-7399) ON 2/19,2/21,2/22,AND 2/25/92 DATE: FEBRUARY 25, 1992 This will probably be the most productive contacts we have had to date, jerry White is co-counsel with Bill Richards (lead attorney) representing some 225 powerline employees in Canada in a case against Dow for 2,4-D and 2,4,5-T exposure along the powerline right of ways between the years 1955 and 1965. This was a ten year spraying program using Dow herbicides of 24D only or 245T only, then both in combination. The concentrations were apparently so heavy that some of these plaintiff's had died while spraying, some on their way home, some died in their yards after they got home, mostly young people and several dying from heart attacks for no apparent reason other than this deadly toxic exposure. I know I haven't even touched the beginning of this, but with the several telephone conferences I have had with Jerry to date he has advised me of the following: 1. He is in possession of some 150,000 to 160,000 pages of documents already stored in his computer indexes which are over 1,500 pages long just for the index of titles. He is already copying all of these for me to take back as a starting point for research. We may have any of these documents we desire. 2. Jerry has been involved in this particular case for the past eight years. The original defendant was the local public utility called "Provincial Utility". He had spent some $500,000 to $600,000 on this case of his own money,when after four years of litigation, they settled for political reasons and have since agreed to completely fund his case against Dow without limit on the funds they will make available to "just get Dow, do whatever it takes". He now has a full home office set up to do just this and apparently does this full time. 3. Examples he gave me of just some of the documents he already has on Dow are: a. Some 200 letters from around the world with medical doctors writing to Dow saying they are treating patients with various diseases connected to 24-D and 245-T exposures, what are they to do and what is in your products? b. Evidence that Dow has had contaminations as high as 14 3940 YELM TELEPHONE CO. F-700 T-976 P-003 FEB 26 ' 92 11:48 parts per million of 2 , 3 , 1 ,8 TCDD in their 245-T herbicide, while Dow still denies they ever exceeded 1-2 ppm of TCDD and instead express their contamination levels at a few parts per billion. c. The first litigation case ever brought against Dow for their chlorinated hydrocarbons (forerunner to 24-D) exposure to humans was in 1934. d. They have just about completed a medically accepted cohort study of these 225 injured or dead workers in which they have hard evidence of numerous causes of death from these herbicides. "It is one hell of a study", says Jerry1 He hopes to have it ready for release in March of 1992. It has cost a fortune to put together, but it will be the best ever on what these herbicides do to humans. e. Based on the excellent medical study done in the 1950's by the German chemical manufacturer, Boehringer Engleheim, there are medically documented cases of various diseases caused to 17 of their own employees in their 1953 chemical plant explosion which spread TCDD everywhere. He has the book on this event. The Germans formally advised Dow of their experiences in the production of these herbicides and strongly advised to immediately change their whole manufacturing process. Apparently Dow did not take heed, because in 1964, Dow had a similar plant explosion at their Midland plant and numerous employees of their's came down with "everything you can imagine". Dow has tried every way to hide the details of this from everyone, but Jerry has all the evidence as to exactly what happened and what Dow has done to try and cover this all up with denials. Jerry said in his opinion, this should not be a civil suit against Dow, but one brought for full criminal conduct with known intent. He does not plan to stop until he "has them nailed". Finally, in 19 66, Dow bought the redesigned production process from Boehringer Engleheim and started to clear up some of their major problems of high TCDD contamination. However, they still have a long way to go as evidenced by the complete banning of 245-T in both the U.S. and Canada. Jerry has the full 1953 documents on just what happened to the German production plant and its workers - f , He has a court order allowing him full access to the very private Dow storage warehouse at Ft. Detrick, Maryland which contains "the whole Dow library of documents". He is already in possession of over 80 rolls of microfilm that contain these documents on them. He only needs to decide what he wants, then go to the warehouse and get it. 4. His case was originally filed in federal court in Midland, Michigan but was removed back to Canada through Dow's efforts. However, the judge made Dow agree to certain stipulations and rules of discovery and Dow has regretted it ever since. They never dreamed Jerry would come up with an unlimited bankroll to fight them on discovery and along with all that, the local 3942. i YELM TELEPHONE CO. F --700 T -9 7 6 P-0 0 4 FEB 26 ' 92 11:49 climate in New Brunswick has completely turned against Dow because of increased publicity and public awareness of what these herbicides really do to humans. This lawsuit will be tried before a judge without jury. Jerry is using as his witnesses all independent scientists and former chemical company employees that he can afford to hire as needed. 5. When I told him we were using Dr. Hardell, Jerry advised that there was a case in Nova Scotia in 1984 where Hardell was supposed to appear, but one of his co-workers had to replace him at the last minute because of scheduling problems. The case was decided in Dow's favor and the court came down hard on what they later came to call "junk science experts". Dr. Hardell's reputation took a beating in Canada at that time because his work appeared to be more of an advocate for the plaintiff that an independent scientist. While this was not the case, the judge held that the plaintiff's experts "had assumed the position of advocates and left the field of independent science" and ruled in Dow's favor. He urged us to be careful how we presented Dr. Hardell as a witness at trial, because Dow will be gunning for him. Hardell has later hurt Dow badly on a case in Nebraska in the late 1980's. 6. My travel plans are to arrive in Fredericton midday on Sunday, March 1. They are on Atlantic Standard Time and will be four hours ahead of Pacific Standard Time. Jerry will meet me at the airport and get me settled in a local hotel near his offices. We plan to spend Monday, Tuesday and Wednesday going over his files and Bill Richards plans to spend one of these days with us also. I will depart after 5 P.M, local time for a flight back to Seattle which gets in late Wednesday night, March 4. 3943 o co co o \ o p P E r K J T M X. r4 O .i : / (, '7 ' u (V 1 {X Z r) ,... - S' u '7. 1 7. 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' 5 3 ,, 7^3i 7 533 . y 6 ' n s Y Y o Y " frs 4 7 7 0 1 co 7 1 0 C jj y i ? -' M7 7 7 0 ^ - 0 ^ t\ ^ q cZ- L; i/V\ tV L O ' ^ ) C^1s >fc. ^ 9 9 / 5597 - % H^ioi __*tV3 Ht%S SO+-u X*. 555 e} z1S~-- 2, Si.^.4 *5 (o (o 5 G09- 53 IX v' S(c(0 5 OU>? X 5335 5 GOO ^ 5'o 3/ 5 >Y -L x: 37 ...5rf ....... >oH9 53 5b w 5>9 7 Til 5.3 GS S/(o 5 79 q S "h ` Z -__ .. 5^.5(p__ ........5?4o..... ........5 b e ; 5C.3 5 P7 5 597G 5 30 3 5333 51^f 5gol 513O'1 53o 3 .5^GH S b ..... so m ___ 5oft> 5 359__ 6 SO? 5 5 5t_ 5 ^ G^ 53 2 (o .. 5SS3 2 MOYER FILE MEMORANDUM TO: RICHARD SCHULER FROM: JOHN BETTS SUBJECT: DOCUMENTS LISTING FROM DOW PRODUCTION (TRIP TO CANADA) DATE: MAY 20, 1992 I have received a computerized listing from Jerry White as a result of the trip I made for you to Fredericton, New Brunswick, Canada to review the microfilm and other records of these Dow production documents and exhibits. Attached to this memorandum are the listings of the specific documents that I ordered copied on your behalf from Jerry White. He and his staff have been in the process of cataloging this massive list of documents for integration into their research files. In addition to this exhibit listing, I was able to secure some choice Dow documents which give specific references to the development of these herbicides and their known effects by Dow on humans, as well as key research papers showing the results of these herbicides on humans, all going back to early years beginning with the development of these chemicals in 1922 by Dow Chemical and ending with a sworn affidavit from Admiral Elmo R. Zumwalt, Jr. who gave the order for these herbicides to be used in Vietnam. (His own son later died of cancer from exposure to 2,4-D and 2,4,5-T while serving in Vietnam.). Attached to this memo is a listing and a brief summary of these documents. K LISTING OF DOCUMENTS 1. "BRIEF HISTORY OF CHLOROPHENOLS AND THE DOW CHEMICAL COMPANY" from 1922 through 1979 showing what Dow knew about the effects of these herbicides. It includes a long recognition of the severe skin disorder known as Chloracne (which is proof of exposure from the dioxin TCDD), early results on humans, animals and plants. It includes secret British research in 1941 that led to the use of these chemicals as a weapon of war which was shared with United States and all known to Dow. It shows how 2,4,5-T was first registered as a herbicide in 1948 to eradicate hardwoods and other woody plants. By 1979, it became known that Dow was the only producer of 2,4,5-trichlorophenol, the chemical intermediate whose production inevitably results in the formation of the deadly carcinogen TCDD. Note references to the Shoecraft v. Dow litigation and the book, "The Dow Story" by Don Whitehead. 2. Various letters to and from Dow between 1952 and 1955 regarding deep concerns of physicians over the exposure of these herbicides to their patients with Dow saying basically that these chemicals cannot be absorbed through the skin and that they will not harm humans (although Dow already had some 20 years of research that proved the opposite). 3. "INDUSTRIAL POISONING IN THE MANUFACTURE OF CHLOROPHENOL COMPOUNDS", a translated German medical study dated 1961 showing the effects of exposures to West German Chemical plant workers to these herbicides beginning in 1950. This report was received by Dow in 1962. The study clearly shows the connection with the deadly dioxins being formally recognized by the German scientists and doctors and the far ranging effects on the health of its workers. 4. "CHLORACNE - DOW EXPERIENCE" , this outline shows Dow's knowledge of these dioxins 2,3,7,8 TCBD and 2,4,5- Trichlorophenol (TCP) which led to the deadly TCDD dioxin that causes cancer in humans. The signal of the exposure of TCDD is the presence of Chloracne in humans. The report shown Dow's own in-house experience with these exposures to its own workers, and outlines the significant cases beginning in the early 1930's. It even shows where they were warned by the Germans in 1957 of the effects of TCP on workers, but the letter was filled and forgotten. 5. Dow letter of September 15, 1977 to "ALL DOW USA SUPERVISORS ON RECORDS RETENTION". It says "when in doubt, throw it away!", because today's memo may be tommorrow's headline. 6. Summary of testimony of JOHN A.. GAROFALO, M.D. in 1983 in the Agent Orange Litigation elaborating on the effect of dioxin on the human immune system. This testimony clearly shows how the dioxin of these herbicides cause cancer in humans. 7. "MORTALITY AMONG U.S. WORKERS EMPLOYED IN THE PRODUCTION OF 3957 CHEMICALS CONTAMINATED WITH 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD)", released on January 1991 by the U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, Centers for Disease Control. It is a retrospective cohort mortality study conducted of 5172 chemical workers from 12 U.S. plants. It says "excess mortality from all cancers combined, respiratory cancer and soft tissue sarcoma, especially in the sub-cohort with more than one year of exposure, is consistent with TCDD being a carcinogen". 8. "AFFIDAVIT OF ADMIRAL ELMO R. ZUMWALT, JR.", given in a New York Federal District Court on August 28, 1991. It blasts the VA study on Vietnam veterans and says they used faulty conclusions and flawed methodology and that new evidence shows a significant association between 2,4-D/2,4,5-T (Agent Orange) and numerous forms of cancer. It claims fraud, manipulation, and interference in the Centers for Disease Control Studies. He also cites political interference, suppression of critical data and the alteration of results of Air Force "Operation Ranch Hand" studies. He swears under oath that any conclusion made in 1984 denying Vietnam veterans were injured by their exposure to Agent Orange was made on the basis of inaccurate and incomplete data, and, therefore, in light of information currently available, has no scientific validity. 9. News article from The Arizona Republic October 13, 1991 on "TOXICS DUG UP, HE BURIES HIS GUILT". It describes the uncovering of a chemical burial site of thirty 55 gallon drums of Silvex (2,4,-D and 2,4,5-TP) by the EPA in September, 1991. It describes how one Herman Najar was ordered to dig a burial site for these illegal chemicals during the investigation of the toxic spraying over the Salt River Project that led to the litigation by Billee Sheocraft against Dow in 1971. After 20 years of silence, he finally spoke up a year ago and led the US Forest Service crews to the 10 deep hole he had bulldozed out 8 feet wide and 40 feet long to dump chese containers in as he was ordered to do. This clipping was sent with a hand written letter to attorney Jack Slobodin of San Francisco and cites how these cancers were proven in court, but "Dow gagged us so as to keep it covered up". 10. THE LANCET, October 19, 1991 article "CANCER MORTALITY AMONG WORKERS IN CHEMICAL PLANT CONTAMINATED WITH DIOXIN", where they report a mortality follow-up of 1583 chemical plant workers in a chemical plant in Germany that produced herbicides contaminated with TCDD going back to 1952. It shows where production of TCDD was reduced from 1954 after an outbreak of chloracne. The results of this study support the hypothesis that TCDD is a human carcinogen. 11. THE LANCET, October 26, 1991 article "CANCER MORTALITY IN WORKERS EXPOSED TO CHLOROPHENOXY HERBICIDES AND CHLOROPHENOLS", where is cites epidemiological studies revealing an increased risk of cancer, notably soft-tissue sarcomas and non-Hodgkin's lymphomas. in people occupationally exposed to chlorophenoxy herbicides, including those contaminated with 2,3,7,8 TCDD. They 3958 report here a historical study of mortality in an international / register of 18,910 production workers or sprayers from ten countries. 12. Arizona Republic news article of 1988 from Fayetteville, N.C. on "ADMIRAL'S SON DIES OF AGENT ORANGE ILLS". It shows how Admiral Zumv,alt's son died of Hodgkin's disease and lymphoma, cancers linked to the toxic herbicides ordered sprayed by him as Agent Orange in Vietnam. 13. DOW PRODUCTION DOCUMENTS - APPENDIX A, PART I. Pages 1 -410 with exhibits numbered 1 - 2851. After reviewing these documents titles and abstracts, I ordered the listed numbers shown on the seven attached pages numbered 1 - 7 (1,260 total documents ordered). These documents include Dow In-House reports, abstracts, news articles, letters, memos, minutes, scientific studies and research papers. 14. DOW PRODUCTION DOCUMENTS - APPENDIX A, PART II. Pages 411821 with exhibits numbered 2852 - 5845. I ordered the listed numbers shown on attached pages 8 - 11 ( 689 total documents ordered). These are a continuation of the types of documents from part I, exhibit A, above. 15. DOW PRODUCTION DOCUMENTS - APPENDIX C, pages 1 - 102 and pages 1- 50 with exhibits numbered C101 to 0552. Dow material data sheets of products, tests made on products, research studies and laboratory reports, a,i.d staff meeting notes/reports. 16. DOW PRODUCTION DOCUMENTS - APPENDIX D, Pages 1 - 8 2 with exhibits 1 - 267; Pages 1 - 2 3 with exhibits W25000 - 25058; mostly unnumbered pages with exhibits 001 - 0557. It includes Agent Orange reports, studies on animals, correspondence, data sheets, product labels, research reports/studies, 17. TRIAL MAGAZINE DECEMBER 1981 article "DIOXIN - MOLECULE OF DEATH" by Victor John Yannacone, Jr. ,et. al. lead counsel for the plaintiffs in re Agent Orange Product Liability Litigation, MDL 381. This article gives a good history of the entire development and use of 2,4-D and 2,4,5-T and how dioxins are what kill and Dow's admission that they have known since 1950 of the possibility of highly toxic impurities formed in their TCP process, when the Germans first isolated dioxin as the contaminant. Dow also admits that they failed to inform either the USDA or the DOD of its findings of dioxin contaminated 2,4,5T and shows that the USDA relied exclusively on toxicological information provided by registrants of pesticides, and was not in the practice of conducting its own research or even monitoring the literature. 18. SCIENCE NEWS, January 11, 1992 article "DIOXINS OTHER FACE", this article explains in detail exactly how dioxin causes cancer by attacking the immune system of the body. This is an excellent study and should be reviewed carefully! 3959 19. "THE OTHER FACE OF 2,4D , A CITIZENS REPORT" published by the South Okanagan Environmental Coalition in Penticton, British Columbia, Canada in January 1978. It shows the substantial threat to the environment and to human health from 2,4-D specifically and phenoxy herbicides in general. It shows how extensive research prior to 1978 has clearly shown 2,4-D to be teratogenic, carcinogenic, and mutagenic. This report was written to get 2,4-D removed from general use in Canada after 2,4,5-T had already been removed. It shows how there is very little chemical difference between all the phenoxy herbicides and the damage they cause to the environment and to humans bears little difference. 20. Documents Ordered from Dow Production Appendix "A" , Parts I & II. (pages 1 - 11). \ MOYER PILE MEMORANDUM TO: RICHARD SCHULER FROM: JOHN BETTS SUBJECT: TRIP TO FREDERICTON, N.B., CANADA FOR MEETINGS WITH JERRY WHITE AND ATTORNEY BILL RICHARDS (MAR 1-4, 1992). DATE: MARCH 5, 1992 This litigation involves a law suit against Dow Chemical U.S. and Dow Chemical Canada filed on behalf of the Sprayers of Dioxin Association (S.O.D.A.). SODA is a citizen organization formed to do battle on behalf of former utility workers who were hired to clear power lines across New Brunswick using a 50/50 mixture of 2,4-D and 2,4,5-T manufactured by Dow Chemical. This was a ten year spray program which took place between 1955 and 1965 during the summer growing season. Most of the sprayers were young men who took this as a summer job and went on to do other jobs throughout Canada in numerous other professions. SODA now represents about 225 former New Brunswick Electric Power employees of which 93 have already died. The injured workers have experienced all types of serious illnesses and cancer related deaths, some occurring at or near the actual job site from massive seizures and heart attacks. Spraying was accomplished from atop a caterpillar tractor driven platform carrying drums of the herbicides with four or more sprayers stationed around the perimeter aiming their nozzle-type wands onto the unwanted brush along the power line right of way. Jerry White was one of these injured employees and is the executive Director of SODA who has sole and exclusive authority to represent and speak for all the plaintiffs. He has been involved full time at' this position for the past 8 years. Prior to that time, he worked in sales for Procter Gamble, but resigned that position to take up this action on a full time basis on behalf of all plaintiffs. The action was first brought against Dow Chemical in Midland, Michigan, but Dow used jurisdictional issues and legal stalling tactics to delay the action from advancing to a court hearing. Since the entire litigation was being supported from money raised by members of SODA, the general public, and interest groups like trade unions, it was draining these funds. Nearly $500,000 had been spent before New Brunswick Electric Power stepped in with an unrestricted and unlimited agreement to finance the entire litigation on behalf of their former employees. This occurred on June 12, 1991 after Jerry White discovered a 1961 memo in the power company files while doing research on Worker's Compensation Claims by former employees. The memo showed NB Power was aware that the inadvertent spraying of raspberry bushes had made several residents sick from eating berries that had been sprayed. The publicity surrounding the lawsuit, which had just been transferred to the New Brunswick Courts on behalf of these dioxin sprayers, now took on an even > ^ 0 5 "? greater potential liability for the NB Power Company to include many potential new plaintiffs who may have been injured through grasslands, watersheds and homesites that were affected by this 10 year spray project. Jerry had attorney Bill Richards of St. John, N.B. draw up the agreement which gives SODA unlimited funds to prosecute this legal action against Dow and even the Power Company cannot see the exact way these funds are spent. An independent accountant verifies that all the bills are made under the terms of the agreement and simply sends the NB Power Corporation a total invoice which is paid in three working days back to the SODA account. After the suit with Dow is concluded, SODA still has the right to pursue legal action against the NB Power if for any reason Dow is not held totally liable for these injuries. Otherwise, NB Power is cooperating completely with SODA to help them prove that Dow is the party liable for products that Dow told NB Power were completely safe to use. Due to the public awareness of this issue in New Brunswick, the massive publicity the case has received, and the fact that an elected local Fredericton Judge will hear this case without a jury, Dow couldn't possibly be in a worse jurisdiction. The orders given by the Michigan federal judge on how discovery would continue when he allowed Dow to transfer this action to New Brunswick, the stipulations made by Dow on agreements for totally open discovery, and the very liberal discovery rules of New Brunswick, Dow is now opening all their files on these products to these plaintiffs. They tried to put a gag order on the documents, and the local judge refused to do it. With this background, I was able to look into some of the most massive legal production I have ever experienced. The computer listings of the documents being made available from Dow are close to 1,500 pages and include over 14,000 documents being shipped weekly to the local Dow counsel in St. John, N.B. and then copied for the plaintiffs locally. Jerry has a full time staff that does nothing but list computer entries of these documents so as to organize them into various litigation categories for the attorneys. During my brief visit, I met several times with Jerry White to discuss the case and twice with Bill Richards to go over the legal theories and their case development. Before going to New Brunswick, I had prepared a complete notebook outlining and listing all the documents I had personally reviewed, along with a summary of the Toxic Tort Defense Seminar given in San Francisco last October for their use. They were pleased to have it. Before leaving, I was able to review some 6,000 plus documents from which I selected about 1,400 initially that were applicable to this specific litigation. Jerry is going to express mail these initial documents to me in the next 10 days and I will continue to review the computer listings and descriptions of documents which remain. In addition, there are about 80 rolls of microfilm documents stored at the Ft. Detrick, Maryland warehouse of Dow that Jerry hasn't had time to review. He just recently ordered an advanced microfilm reader to have his staff start reviewing these additional documents to determine what else they may want Dow to produce for them. 3962 As soon as I receive the documents I have ordered from Jerry, I will review them and get an index of exhibits list prepared for you. During the next week, I will be tied up on other matters, but will complete this after March 13 when I receive the initial documents from Jerry. This was a most productive trip and I am sure these documents will prove to be an invaluable source of information. Just reading the documents list and their short descriptions was like reading one of the best novels you could ever imagine for telling the true Dow story on these herbicides. 3963 3 SS 0 ^p-^/0fc EXHIBIT I IN THE UNITED STATES DISTRICT COURT FOR THE EASTERN DISTRICT OF NEW YORK SHIRLEY IVY, Individually and as Representative of the Estate of DONALD IVY, et al. Plaintiffs, v. DIAMOND SHAMROCK CHEMICALS COMPANY, et al. Defendants. [] [] N [] [] [] CV-89-03361 (E.D.N.Y.) (JBW) [] [] [B-89-00559-CA (E.D.TEX.)] [] [] [] [] [] [] AFFIDAVIT OF ADMIRAL ELMO R. ZUMWALT. JR. BEFORE ME, the undersigned authority, appeared Admiral Elmo R. Zumwalt, Jr., USN (Ret.), 1500 Wilson Blvd., Arlington, VA 22209, and after being duly sworn does testify and declare as follows: 1. From 1968 to 1970 I served as the Commander of U.S. Naval Forces, Vietnam. From 1970 to 1974 I served as the Chief of Naval Operations and a member of the Joint Chiefs of Staff. 2. On October 6, 1989 I was appointed Special Assistant to Secretary Derwinski of the Department of Veterans Affairs ("VA") to assist the Secretary in determining whether there is a significant ("as likely as not") statistical association between exposure to Agent Orange and any specific adverse health effect. 3. As Special Assistant, it was my duty, with the assistance of independent scientific experts, to do the following: 1) evaluate scientific studies regarding the health effects of Vietnam veterans exposed to Agent Orange, as well as numerous studies concerning the health hazards of civilian exposure to dioxin contaminants; 2) review and evaluate the protocol and standards employed in the major government sponsored studies, in order to assess their credibility, fairness and consistency with generally accepted scientific practices; and 3) review and evaluate the work of the Scientific Council of the Veterans' Advisory Committee on Environmental Hazards. 3965 I. NEW EVIDENCE SHOWING A SIGNIFICANT ASSOCIATION BETWEEN AGENT ORANGE EXPOSURE AND CERTAIN HEALTH EFFECTS 4. There is mounting evidence of a causal connection between certain illnesses and exposure to dioxins. After reviewing the scientific literature, I have concluded that the following illnesses are significantly associated with exposure to Agent Orange: non-Hodgkin's lymphoma, chloracne and other skin disorders, lip cancer, bone cancer, soft tissue sarcoma, birth defects, skin cancer, lung cancer, porphyria cutanea tarda and other liver disorders, Hodgkin's disease, hematopoietic diseases, multiple myeloma, neurological defects, auto-immune diseases and disorders, liver cancer, nasal/pharyngeal/esophageal cancers, leukemia, malignant melanoma, kidney cancer, testicular cancer, pancreatic cancer, stomach cancer, prostate cancer, colon cancer, brain cancer, psychosocial effects, gastrointestinal diseases, diabetes, and cardiovascular abnormalities. 5. In addition to my report on the scientific studies showing an association between health effects and Agent Orange exposure, I have reviewed the affidavit of Dr. Cate Jenkins submitted in this action. Dr. Jenkins' affidavit compiles a growing number of studies showing a link between dioxin exposure and serious health effects. This extensive list of positive studies, all published in 1984 or later, further supports my conclusions stated above. II. FAULTY CONCLUSIONS, FLAWED METHODOLOGY AND NOTICEABLE BIAS OF THE VA ADVISORY COMMITTEE ON ENVIRONMENTAL HAZARDS 6. In 1984, Congress passed the Veterans' Dioxin and Radiation Exposure Compensation Standards Act, Pub. L. No. 98-542, 98 Stat. 2727 (1984) (the "Dioxin Standards Act") to provide disability compensation to Vietnam veterans exposed to herbicides containing dioxin. Congress authorized the VA to conduct rulemaking to determine which diseases were entitled to compensation as a result of a service-related exposure to Agent Orange. The Dioxin Standards Act required the VA to appoint a Veterans' Advisory Committee on Environmental Hazards (the' "Advisory Committee") to review the scientific literature on dioxin and submit periodic recommendations and evaluations to the Administrator of the VA. The Advisory Committee is composed of experts in dioxin and epidemiology, as well as interested members of the public. The responsibility of the experts is to evaluate the scientific evidence pursuant to regulations promulgated by the VA and thereafter to submit recommendations and evaluations to the Administrator of the VA (subsequently the Secretary of Veterans Affairs) on whether "sound scientific or medical evidence" indicated a connection between exposure to Agent Orange and the manifestation of various diseases. D '-H o g q . 7. To assess the validity and competency of the work of the Advisory Committee, I asked several impartial scientists to review the Advisory Committee transcripts. Without exception, these independent experts who reviewed the work of the Advisory Committee disagreed with its findings. They specifically questioned the validity of the Advisory Committee's review of studies on non-Hodgkin's lymphomas. The Secretary subsequently exercised his discretionary authority to find a significant statistical association between Agent Orange exposure and nonHodgkin's lymphoma, notwithstanding the failure of his own Advisory Committee to recommend such action in the face of overwhelming contrary scientific data. 8. On February 20, 1990, experts from the Fred Hutchinson Cancer Research Institute in Seattle, Washington ("Hutchinson Cancer Institute"), having reviewed the VA's analysis of studies on nonHodgkin's lymphoma, concluded that the VA Advisory Committee's work was "not sensible" and was "rather unsatisfactory" in its review and classification. These scientists regarded certain members of the Advisory Committee as being "less than objective" in their review of the various studies. 9. On March 1, 1990, after assessing numerous cancer studies relevant to herbicide exposure, Dr. Jeanne Stellman, Ph.D., and Dr. Steven D. stellman, Ph.D., reached the same conclusions as the experts from the Hutchinson Cancer Institute concerning the validity of the VA Advisory Committee's findings. The Stellmans' assessment of numerous cancer studies relevant to herbicide exposure strongly criticizes the Advisory Commmittee's scientific interpretation and policy judgments regarding the link between Agent Orange and Vietnam veterans. See Stellman & Stellman, "A Selection of Papers with Commentaries Relevant to the Science Interpretation and Policy: Agent Orange and Vietnam Veterans," (March 1, 1990). 10. On March 7, 1990, Dr. Robert Hartzman, one of the U.S. Navy's top medical researchers, also confirmed the views of the scientists from the Hutchinson Cancer Institute. Dr. Hartzman stated, "an inadequate process is being,used to evaluate scientific publications for use in publ'ic policy." He further concluded that "the preponderance of evidence from the papers reviewed [by the Advisory Committee] weighs heavily in favor of an effect of Agent Orange on increased risk for non-Hodgkin's lymphoma." 11. Dr. Richard Albanese, a scientist intimately associated with government sponsored studies on the effects of exposure to Agent Orange, also reviewed the Advisory Committee's findings. He concluded that the Advisory Committee's work "has little or no scientific merit, and should not serve as a basis for compensation or regulatory decisions of any sort . . . " In 3 another paper, Dr. Albanese stated, "I estimate that the [Vietnam] Veterans are experiencing a 40% to 50% increase in sarcomas and non-Hodgkin's lymphoma rates." 12. In the course of my duties as Special Assistant to the Secretary of Veterans Affairs, I concluded that the Veterans' Advisory Committee on Environmental Hazards has not acted with impartiality in its review and assessment of the scientific evidence related to the association of Agent Orange with adverse health effects. III. FRAUD. MANIPULATION. AND INTERFERENCE IN THE CENTERS FOR DISEASE CONTROL fCDC^ STUDIES 13. In addition to the numerous new scientific studies published after 1984 showing an association between Agent Orange exposure in Vietnam and certain adverse health effects, there is new evidence that the data for studies conducted by the Centers for Disease Control (CDC) was manipulated by CDC in an effort to deny the link between Agent Orange exposure and health effects. New evidence also shows that political interference obstructed the CDC exposure study. 14. As concerns grew following the initial studies connecting Agent Orange exposure to adverse health effects, Congress commissioned a large scale epidemiological study to determine the potential health effects of Agent Orange on exposed Vietnam veterans. The Veterans Health Programs Extension and Improvement Act of 1979, Pub. L. No. 96-151, 93 Stat. 1097 (1979), authorized the VA to design and conduct the study. In 1981, Congress enacted the Veterans Health Care, Training, and Small Business Loan Act, Pub. L. No. 97-72, 95 Stat. 1061 (1981), which expanded the scope of the VA study to include a health study of Vietnam veterans, using service during the war as an exposure factor. However, in 1983 Congress transferred the responsibility for the study to CDC when it became evident that the VA's efforts were mired in delay. Three years after the passage of this legislation, the VA had not even begun the study. 15. The Human Resources and Intergovernmental Relations Subcommittee (the "Subcommittee") has investigated CDC studies conducted from 1982 to 1987. As a part of the Subcommittee's year-long investigation, public hearings were conducted on July 11, 1989 and on June 26, 1990 at which time I presented testimony on the findings of my report as Special Assistant to the Secretary of Veterans Affairs. As the hearings revealed, the design, implementation and conclusions of the CDC dioxin exposure study were so ill conceived and unscientific as to suggest that political pressures interfered with the kind of professional, unbiased review Congress sought to obtain. Oversight Review of CPC's Agent Orange Study: Hearing Before the Human Resources and Intergovernmental Relations Subcommittee of the Committee on 4 3968 Government Operations. House of Representatives, 101st Cong., 1st Sess. (1989) ("1989 Agent Orange Hearing"). Links Between Agent Orange and Other Herbicides With Diseases: Hearing Before the Human Resources and Intergovernmental Relations Subcommittee of the Committee on Government Operations. House of Representatives. 101st Cong., 2d Sess. (1990). 16. On August 9, 1990, the Committee on Government Operations (the "Committee") submitted its Twelfth Report to Congress. The Committee's report is based on extensive investigation of the studies of Agent Orange exposure and Vietnam veterans' health conducted by the Centers for Disease Control (CDC) from 1982 to 1987. The Agent Orange Coverup;__ A Case of Flawed Science and Political Manipulation. Twelfth Report bv the Committee on Government Operations Together with Dissenting Views. H.R. Rep. No. 672, 101st Cong., 2d Sess. 1-43 (1990). 17. The following statements include findings from the July 11, 1989 hearing and the July 26, 1990 hearing at which I testified. My statements also refer to the conclusions of the Committee on Government Operations which I support and adopt based on my own independent review of the evidence, in my capacity as Special Assistant to the Secretary of Veterans Affairs during the period in which I conducted the study for him. 18. In September 1987, CDC canceled the Agent Orange Exposure Study. The Committee believes, as I do, that there was a twopart strategy selected by the CDC that guaranteed the eventual cancellation of the study. As the Committee concluded, first, CDC ignored the military records experts at the Pentagon, created its own use of the records to establish exposure levels, and then diluted the study to the point that numerous veterans who were most likely to have high exposure were eliminated from the study; second, CDC attempted to justify its flawed exposure definition by testing it against a blood serum assay program which, itself, was based on false assumptions about the chemical's half-life in the human body. These unsound assumptions about the half-life of dioxin were thus used to validate the conclusions from a badlydesigned exposure definition. Given these restrictions, it would have been impossible to validate exposure levels. t 19. From my independent review of the evidence stated below, which I conducted as Special Assistant to the Secretary of Veterans Affairs, I agree with the Committee on Government Operations' conclusion that the Agent Orange exposure study should not have been canceled because CDC did not document its conclusion that exposure could not be assessed, nor did it explore alternative methods of determining exposure. The Committee concluded, as I do, that as discussed below, other methods of determining exposure were available but that CDC had intentionally disregarded them. 5 3989 s' 20. The Centers for Disease Control cited the inadequacy of military records regarding troop movements and the spraying of Agent Orange as the primary reason for the cancellation of the exposure study. The former Director of the U.S. Army and Joint Services Environmental Support Group ("ESG"), Lt. Col. Richard S. Christian (Ret.), disagreed with the CDC claim that military records were insufficient. Lt. Col. Christian testified that adequate military records do exist with which to identify company-specific movements, as well as spray locations, and that he had personally informed CDC of the existence of these records. 1989 Agent Orange Hearing 40-43 (statement of Richard S. Christian). The Committee found that CDC had unjustifiably discredited the military records provided to it by ESG. 21. Dr. Jeanne Stellman of Columbia University, who conducted a peer reviewed epidemiologic study for the American Legion, testified before the Subcommittee that available records were quite sufficient to establish a reliable exposure classification system. This American Legion-Columbia University study conclusively demonstrated that computerized data could be used to determine exposure to Agent Orange. 1989 Agent Orange Hearing 155-220 (statements of Steven Stellman, Ph.D. and Jeanne M. stellman, Ph.D.), See also "American Legion and Columbia University Vietnam Experience Study," Environmental Research (December, 1988). 22. Dr. Dennis Smith, who worked on the CDC Agent Orange Project, was one of the people responsible for evaluating records provided to CDC by the Department of Defense. Dr. Smith testified that he and others at CDC believed that sufficient information existed to compensate for gaps in the military records transmitted by the Pentagon. He testified, however, that his superiors were resistant to exploring the alternatives. 1989 Agent Orange Hearing 76-110 (statement of Dennis M. Smith, M.D.). 23. in addition to CDC#s false claim that military records were inadequate, there were other flaws with the CDC exposure study effort. When the protocol for this study and blood test procedures were examined, there appeared to be a purposeful effort to sabotage any chance of a meaningful Agent Orange exposure analysis. The Committee found, as I do, that the protocol for the CDC study had been changed from its original format, making it unlikely that the soldiers who received the heaviest exposure to the herbicide would be identified. 24. The Committee found, consistent with my analysis, that from the start CDC had disregarded the records of soldiers who would have been among the most likely to have been exposed. The original protocol contained numerous restrictions which had the effect of arbitrarily limiting the number and type of veterans selected for the study. Thus, only a small percentage of 6 3970 available records were reviewed by CDC. 25. CDC further diluted the study by adding more restrictions to the criteria for the inclusion of subjects that were not contained in the original protocol. 26. The Committee found, as I do, that CDC made four serious modifications in the original protocol, the most serious being the selection of study subjects from battalions rather than companies. Originally, the study had called for subject veterans to be tracked by company level location. Company units of 200 men, rather than battalions of 1,000 men, were to be tracked to obtain greater precision for determining troop movements and to prevent raisclassifying whether or not veterans had been exposed. Then, in 1985, CDC changed its protocol to have battalions serve as the basis for cohort selection and unit location. This change, as CDC admitted, diluted the study. 27. Another protocol change made by CDC involved the alteration of the protocol as to the length of time study subjects were to have served in Vietnam. For example, where the original protocol reguired subjects to have served a minimum of 9 months in combat companies, the CDC reduced the minimum to 6 months. These changes further diluted the study by reducing both the possibility that study subjects would have been exposed to Agent Orange and the degree of exposure. 1989 Agent Orange Hearing 46-49. See also 1989 Agent Orange Hearing at 149 (statement of John F. Sommer, Jr., Director National Veterans Affairs and Rehabilitation Commission, the American Legion). 28. As mentioned previously, CDC and the White House Agent Orange Working Group ("AOWG") primarily based its decision not to go forward with the study on its criticism of the ESG records. However, before the study was canceled, CDC tested its exposure definition by means of a "verification study" comparing blood tests with company placement records. At a meeting of the AOWG Science Panel on June 17, 1986, the Science Panel concluded that, "There is unanimous agreement that if a well-designed exposure verification study fails to validate individuals' exposures as determined from military records, the Agent Orange Epidemiological Study should be discontinued." 29. Thus, CDC based its conclusion that an exposure study could not be done, not only on the purported inadequacy of herbicide spray and troop movement records, but also on the results of blood tests of Vietnam veterans which ostensibly demonstrated that no association existed between serum dioxin levels and CDC's estimates of the likelihood of exposure to Agent Orange based on those same records. Inexplicably, the CDC then used these "negative" findings to conclude that not only could an exposure study not even be done, but that the "study," which was never even conducted, proves that Vietnam veterans were never exposed 7 3971 D -y c.t7 to harmful doses of Agent Orange. 30. As the Committee concluded, the blood serum analysis, used as proof that an exposure study could not be conducted, was based on erroneous assumptions and a flawed analysis. For example, C D C 's conclusion that the half-life of dioxin in the human body is 7.1 years was reached in disregard of warnings from CDC's own scientists and the National Academy of Sciences Institute of Medicine ("IOM") peer review committee that there was not sufficient evidence to support the longer half-life. IOM informed CDC that, because of the incorrect assumptions about the half-life of dioxin, the conclusions of the blood study were not supportable. IOM also rejected CDC's conclusion about the inadequacy of military records as a basis for exposure estimates, independent of any blood serum analysis. 31. In his testimony, under questioning from the Subcommittee Chairman, Rep. Weiss, Dr. Vernon Houk admitted that the senior statistician on the Agent Orange project believed that the dioxin blood analysis was so flawed that it had "a substantial likelihood that there would be essentially no correlation1* between the exposure scores and the blood levels. Dr. Houk disagreed with this officially expressed opinion of the project's senior statistician and supported the validity of CDC's blood serum analysis. 1989 Agent Orange Hearing at 67 (statement of Vernon N. Houk, M.D., Director, Center for Environmental Health and Injury Control, Centers for Disease Control, U.S. Department of Health and Human Services). 32. In the course of my duties as Special Assistant to the Secretary of Veterans Affairs I have specifically reviewed the work of Dr. Vernon Houk in connection with Agent Orange studies, both in his capacity as a member of the AOWG and as a CDC official. It is my conclusion that Dr. Vernon Houk has made it his mission to manipulate scientific data and procedures so as to prevent the true facts about dioxin from being determined. Continuing to pursue this effort, Dr. Houk has been recently quoted in Time magazine, Aug. 26, 1991, The New York Times. Aug. 15, 1991, St. Louis, Washington, and other newspapers and media outlets, in an apparent public relatiorvs campaign; falsely claiming that previous assessments of the harmful effects of dioxin have been overestimated. These articles cite no credible basis for Dr. Houk's opinion. I consider this media campaign further evidence of Dr. Houk's attempts to cover up emerging evidence strongly confirming the harmful effects of dioxin. 33. Dr. Houk's politically motivated efforts to cover up the true effects of dioxin, and manipulate public perception, coincide with the similar, economically motivated, efforts of chemical companies that produce dioxin. They are, in my judgment, responsible for letters and articles that have been published in the media discounting the effects of dioxin on human 8 3972 health. These chemical companies that place profits above other concerns, were very cunning in working out the 1984 Agent Orange settlement deal before all the scientific information -- such as that now presented in Dr. Jenkins' affidavit in this case or the disclosures recounted here about the way in which the supposedly objective government studies were manipulated -- became available. It is apparent that these same companies are now attempting to support the validity of that settlement, at the very time it is under review in this case, by means of a public relations campaign centered around the statements of Dr. Vernon Houk, whose work on the CDC Agent Orange study has been thoroughly discredited. 34. Upon discovering the irregularities in CDC procedures, Dr. Philip Landrigan, who was the former Director of the Environmental Hazards Branch at the CDC, stated: "Suspicion abounds that CDC did not look deeply enough into the existing records and did not exercise sufficient ingenuity in seeking to identify a potentially heavily exposed subset of veterans. . . . Further, I would argue that CDC should itself be raising the question." 1989 Agent Orange Hearing at 229 (statement of Philip J. Landrigan, M.D.). 35. In 1986, the Subcommittee on Oversight and Investigations of the Committee on Energy and Commerce documented how political officials of the Office of Management and Budget ("OMB"), who were untutored in science, interfered with and second-guessed the professional judgments of agency scientists and multidisciplinary panels of outside peer review experts to effectively alter or forestall CDC research on the effects of Agent Orange, primarily on the grounds that "enough" dioxin research had already been done. OMB Review of CDC Research: Impact of the Paperwork Reduction Act; A report Prepared for the Subcommittee on Oversight and Investigations of the Committee on Energy and Commerce. 99th Cong., 2nd Sess. (1986). 36. The Committee on Government Operations' Agent Orange hearings revealed additional examples of political interference in the CDC's Agent Orange projects by members of the White House Agent Orange Working Group. Evidence o'f political interference in the design and implementation of the CDC study and drafting of the results of the CDC study by Administration officials rather than CDC scientists, further destroys the credibility of the CDC exposure study efforts. The Committee concluded from this evidence, as do I, that the CDC study of the effects of dioxin on Vietnam veterans was controlled and obstructed by the White House, primarily through its AOWG and the OMB so as to prevent any useful findings by the CDC concerning the effects of Agent Orange. This obstruction was done pursuant to a strategy for denying liability in cases of toxic contamination. 9 3973 IV. POLITICAL INTERFERENCE. SUPPRESSION OF CRITICAL DATA. AND THE ALTERATION OF RESULTS IN AIR FORCE "OPERATION RANCH HAND" STUDIES 3 7 . The Air Force Health Study is a separate government sponsored epidemiologic investigation to determine whether certain adverse health effects among Air Force veterans who participated in the "Operation Ranch Hand" Agent Orange spraying missions, were caused by exposure to the herbicide. This study consists of both mortality and morbidity components. 38. On January 24, 1984, Air Force scientists studying Vietnam veterans who had participated in the Ranch Hand spraying missions, issued a draft of baseline morbidity study results. The draft was prepared for the Ranch Hand Advisory Committee. In its final conclusion, the study states, "It is incorrect to interpret this baseline study as 'negative'. . . The Ranch Hand study discloses numerous medical findings, a few of concern but most of a minor nature that merit complete and proper follow-up in accordance with the study protocol. The fact that the study findings are not wholely [sic] consistent with the bulk, of RVN [Republic of Vietnam] veteran complaints may be somewhat reassuring to the Ranch Handers and to their families at this time." "Air Force Health Study (Project Ranch Hand II): An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides: Baseline Morbidity Results." Air Force Working Draft Prepared for Advisory Committee (January 24, 1984). 39. Then, on February 24, 1984, after the Ranch Hand Advisory Committee, which operates under the White House Agent Orange Working Group of the Domestic Policy Council, had reviewed the January 1984 working draft, the Air Force issued the final version of the baseline morbidity study results. The Ranch Hand Advisory Committee had changed the final conclusion of the report from the January working draft version in some very important ways. The February 1984 version no longer stated "It is incorrect to interpret this baseline study as 'negative.'" The February final draft conclusion stated,/"This study has disclosed numerous medical findings, mostly of a minor or undetermined nature, that require detailed follow-up. In full context, the baseline study results should be viewed as reassuring to Ranch Handers and to their families at this time, because this study has not identified statistical group differences for illnesses commonly attributed to dioxin exposure. . . . This baseline report concludes that there is insufficient evidence to support a cause and effect relationship between herbicide exposure and adverse health in the Ranch Hand group at this time." Lathrop, G.D., W. H. Wolfe, R. A. Albanese, and P.M. Moynahan "Air Force Health Study (Project Ranch Hand II): An Epidemiological Investigation of Health Effects In Air Force Personnel Following 10 3974 Exposure to Herbicides: Baseline Morbidity Results" (February 2 4 , 1984). 40. By altering the study's conclusion just prior to the May 1984 settlement of In re Agent Orange Product Liability r,iticiation. opponents of Agent Orange compensation were able to topoint "irrefutable proof" that Agent Orange is not a health problem. If those veterans most heavily exposed to Agent Orange did not manifest any serious health problems, they argued, then it could safely be deduced that no veteran allegedly exposed to Agent Orange in smaller doses could have health problems. 41. On March 9, 1990, Senator Daschle reported to Congress that the changes in the draft of the baseline morbidity study, after the Advisory Committee operating under the White House Agent Orange Working Group reviewed it, show political interference in the Air Force Ranch Hand study. When Senator Daschle inquired of Air Force scientists why discrepancies existed between an Air Force draft of the Ranch Hand Study and the final report actually released to the press, the answers suggested the perpetration of fraudulent conclusions. As Senator Daschle pointed out, Air Force and White House management representatives were involved in scientific decisions in spite of the study's protocol which prohibited such involvement. 136 Cong. Rec. S2551 (1990) (statement of Sen. Daschle). 42. Not until 1987 did it become clear that the Air Force had also suppressed critical data in 1984 when Ranch Hand scientists confirmed that an unpublished report had shown that birth defects among Ranch Hand children were double those of the control group. 135 Cong. Rec. S16543 (1989) (statement of Sen. Daschle). 43. This December 17, 1984, Air Force birth defects study concluding that "There was an increase in the risk of Ranch Hand birth defects with time (pre versus post - Southeast Asia), and this change is statistically significant," had remained unpublished. The study also concluded, "A significant change in risk of the occurrence of neonatal death was noted . . . " USAF School of Aerospace Medicine, "Project panch Hand.II: An Epidemiological Investigation of Health Effects In Air Force Personnel Following Exposure to Herbicides: Reproductive Outcome Update," WORKING DRAFT - NOT FOR PUBLIC RELEASE (December 17, 1984). 44. In an August 25, 1987 letter to Senator Daschle, Colonel William Wolfe, Chief of the Epidemiology Division for the Air Force, explained the reason why the Air Force birth defects study remained unpublished. "A report of the analyses of these data was submitted to the Advisory Committee in 1984 but they recommended that it not be published." 3975 D ' 7 / V. CONCLUSION 4 5 . It is my conclusion drawn from my analysis of the available evidence, in connection with my duties while I served as special assistant to the Secretary of Veterans Affairs, that: 1) The major federal government health studies on the effects of Agent Orange on Vietnam veterans have significantly understated those effects as a result of deliberate political manipulation of scientific data and methodology. 2) Numerous studies done by scientists who. work independently of either such political influence, or the conflicting interests of the corporations who produced Agent Orange, provide valid scientific evidence that Agent Orange has caused a variety of adverse health effects among veterans exposed to the herbicide in Vietnam. 46. The information upon which these conclusions are based has for the most part become available only after 1984. Any conclusion made in 1984 denying that Vietnam veterans were injured by their exposure to Agent Orange was made on the basis of inaccurate and incomplete data, and, therefore, in light of information currently available, has no scientific validity. The foregoing affidavit is a true and accurate statement of my testimony in the above-captioned case to the best of my knowledge and belief. Admiral Elmo R . Zumwalt, Jr. Signed and sworn before me by Z m 0 'R . U Xfr this Jg*4- day of __ , 1991. . QQf My commission expires on the H day of HUQUiJ / i % . SIGNED: N a & u d '4 . Notary Public 12 _P" H07O- 9 JP'VotfS B4 The Arizona Republic Sunday, October 13, 1991 Worker buries feelings of guilt as toxic chemicals are dug up -- WORKER, from fage B l snowmelt into the lakes serving the desert in Arizona. In June 1969. the silvex spraying was carried out at two canyons. Icehouse and Kellner, south of Globe. Several residents of the area were sprayed as they watched the helicop ter, and one of them. Billeg Shoecraft, died nine years later of leukemia, which she believed was caused by the spraying, although it never was proved. Forestry officials are uncertain why Middle Mountain was Dicked for the dump site, out ion a bedeii, supervisor the Apache-Sagreaves National rest, offered this theory: "Probably in the heat of oattle, some guys decided they had to put it somewhere, and they picked t site that was as remote as it could lie." Najar's first contact with silvex occurred in 1971, hree years after he went to work as a heavy-equipment operator with the Forest Service in the Alpine area. "There was a bunch of us up here (on Middle Mountain) piling up brush from a timber sale." said Najar. who lives in Alpine. "And one day, some Forest Service guys I'd never seen before drove up ir. a truck and said they had something that had to be buried right away, and I did as I was told." Najar maneuvered his D-6 Cater pillar to the edge of a small clearing -just below an old logging road and dug a hole about 10 feet ceep. S feet wide and 40 feet long. After the cargo was buried, he covered it up. But he didn't forget. " I always wondered what was in those barrels," Najar said. "And I always wondered if I was doing the right thing by not saying anything about it." A little more than a year ago. he decided he'd speak up. after he attended a Forest Service seminar on hazardous materials. "We're pleased that he did." said Walt Brooks of Eagar. forest engineer for the Apache-Sitgreaves National Forest. "No one around hc.e had any idea what was up there. "And instead of giving him a bad time, like might have happened someplace else, we gave Herman a SI.000 award." Forest Service crews took their first look at the Middle Mountain dump in the summer of 1990 and discovered that the dump didn't appear to have damaged the surrounding forest. After unearthing one 55-gallon drum, which by then had developed a leak, they decided to seal off the site and wait before doing any more digging. Lab tests later confirmed that the liquid seeping from the drum was silvex. Brooks said, but the Forest Service was unsure how to proceed with a cleanup, and it did not have the money. The budget problems were solved by including cleanup funds in the agency budget that started July 1. Then the EPA was called in for its expertise. The cleanup started Sept. 28. Gathered at the edge of the ; mountain meadow were the EPA , disaster-cleanup coordinator, a two- : man crew from the Coast Guard's * Pacific strike team, which deais with ' hazardous materials, and a four-mem- ' ber crew from Disposal Control 1 Service, a Phoenix firm that deals in j the cleanup of hazardous-material j spills. | A backhoe and its operator probed : the hole. Men wearing protective j "moon" suits climbed in and out of i the pit. tying barrels to the backhoe 1 bucket for removal. The iiquid chemi- j cal was pumped into new barrels. : which later will be stored in' a j hazardous-material warehouse. i The earth that had surrounded the \ old barrels was spread onto the logging road. There it was mixed with \ sawdust and fertilizer, and this pro- I cess, with help from Mother Nature, should result in decontamination of the soil in about a year. The total bill for the cleanup, and for building an 8-foot-high fence around the dump, is expected to run i about S100,000, Brooks said. ; The dump is not believed to have ; caused any environmental damage, said Robert Mandel. EPA cleanup coordinator based in San Francisco. Five families living in Icehouse and ! Kellner canyons sued the federal government and several chemical firms over the spraying program. The lawsuit was settled out of court. Toxics dug up, he buries his guilt By Frd Smith The Arizona Republic ALPINE -- Twenty years ago, Herman Najar participated in a graveside service in a pretty mountain meadow 10 miles southwest of Alpine, and the interment later became a nightmare that wouldn't end. But late last month, Najar's con science was cleared. As Najar watched, a crew super vised by the U.S. Environmental Protection Agency uncovered the burial site on Middle Mountain and removed about 30 containers filled with a toxic chemical that once figured in the history of Globe, which is far from Middle Mountain. That chemical is silvex, a defoliant much like Agent Orange, which was used in the jungles of Vietnam and later became the subject of numerous lawsuits filed by soldiers who came in contact with it. In the Globe area, silvex was sprayed by helicopter in a cooperative program between the U.S. Forest Service and the Salt River Project in the late 1960s to rid canyons of plants that were believed to impede water runoff. Removing the vegetation, according to belief? at the time, would increase the water flow from winter -- See WORKER, page B4 3978 Q -H oW \ -~ Z 7 * ~ /v h a X ^ O O ( ^ C y=2^-u3f" W -f Q ^\b -L A^si - ~ /~ A jZ y h ^ -n & s it A*S**-er*~j C f- ^ t rt* * * * -^ - *^L *5 ^ jL tJ L s y i ' <>< ^ yv f f y - t w f O r c K ^ t * o ~ \j? ^ ^ -d /ty ^ e . e ^ v } tfi cM 7?X - ^ /VKV^ ' f &<'( ^ sfP o **-<* ** `f - f p ~ ^ s-r~ 'wujj- < ^ -W ^ h I o y h& -c{L o b l i l i c nts^P <2-c7Wcl<:c~ ^ ^ 1 . C J f* -^ d & 7 ^ r> x -laP (s ^ ~ { S y v 3 . **a S 0 ~ ^ ^ -o *4/1 *-- H(f_ / ' d h .J j s 0 ) (S' V * J T ' S^jp ~ 7s { < S S' c^t3 >Q .d) LC?( f ? ( l* ~7~fvts i*r+-*- Xu CLo v P T fa f>q 10 STa~t <^.<6^ I X jl ^ s > -- v f ~ ~ x ~ h -y <S~S ~ T * / < * * f t l ~ Q . V V J P r ' * <P 0^ \ < /S S O d o M oA (L d J/.. B4___ TV Wc as snowmelt : desert inA In Jn wts cage IcehoaMSr Severi!: sprayed ter, andai itiwl which a f spraying,! TS Middle Me dump sttS of t h e Forest, offe in die lie decided Ac and they?; remote Mi: Near's occuiredA went to * operatorw Alpine aiet `T h ere' (on Middle from a tm lives in Al Forest Set before dro' they had : buried riffe told." Najar n pillar to tfe below 3979 9 - Vo7s' 3980 D .>14.: THE LANCET Vol 338 Saturday 19 October 1991 No 8773 Cancer mortality among workers in chemical plant contaminated with dioxin A. Manz J. Berger J. H . Dwyer D. Flesch-Janys S. N agel H . Waltsgott Dioxin (2,3,7,8-tetrachlorodibenzo-p:dioxin or T C D D ) can arise as a contaminant in the production of herbicides. It causes chloracne in those exposed to it but its human carcinogenicity has been a matter of dispute. W e report here a mortality follow -up of 1583 workers (1 1 8 4 men, 399 w om en) employed in a chemical plant in Germany that produced herbicides, including processes contaminated w ith TCDD . Production of T C D D was reduced from 1 9 5 4 after an outbreak of chloracne. Vital status up to 1989 was determined for 97-1% of workers hired between 1 9 5 2 and 1984, and 367 deaths (3 1 3 men, 54 w om en) were recorded. A malignant neoplasm was the underlying cause of death in 93 men and 20 women. Standardised mortality ratios (S M R ) were calculated w ith, as references, national mortality statistics for West Germany and deaths in a cohort of male gas workers; for total cancer mortality they were 1 -24 (95% confidence interval 1 -0 0 -1 -5 2 ) and 1-39 (1 -10-- 1-7 5), respectively, among men. Cancer mortality was increased among men with 20 or more years of employment (S M R = 1-87 [Germany] and 1-82 [gas workers]) and among men w ho began employment before 1 9 55 (S M R = 1-61 and T 8 7 ). The group with suspected highest exposure to T C D D had SM Rs of 1-42 and 1-78. Only 7% of cohort women worked in the high exposure locations in the plant, compared with 39-6% of men, and no increased risk of cancer mortality was observed among women; but breast cancer mortality was raised (S R M = 2-15). These results, together with a US occupational study and a German investigation of accidental exposure, support the hypothesis that T C D D is a human carcinogen. Lancet 1991: 338: 959-64. > Introduction Although a relation between risk of malignancy at several sites and exposure to 2,3,7,8-temchlorodibenzo-p-dioxin (dioxin, T C D D ) has been observed in animals,11the human carcinogenicity of T C D D remains controversial.*-1 The debate stems primarily from inconsistent findings in case-referent studies relating risk o f soft-tissue sarcoma or non-Hodgkin's lymphoma to herbicide exposure. Several investigators have detected a positive association4-'' but others have n o t1011 Epidemiological associations between T C D D exposure and other cancers have also been reported.1- " Follow-up of a U S cohort of over 5000 TCDD-exposed workers has added substantially to the evidence. Fingerhut et al" found an increase in mortality from all cancers (standardised mortality ratio [SMR] = 1-46; 95% confidence interval [Cl] 1-21-1-76), and from respiratory cancer and soft-tissue sarcoma in men exposed to T C D D for more than a year and with an opportunity for a minimum latency o f 20 years. The finding for all cancers is consistent with a German study o f 247 workers exposed to T C D D during a thermochemical accident in 1953.15 There was a significant increase in total cancer mortality (SM R = 2-01 [1 -22-3-15]) in the subgroup with chloracne and more than 20 years since exposure. We describe here a retrospective cancer mortality study of chemical workers employed in an herbicide plant in Hamburg. The plant was heavily contaminated with T C D D from the production o f trichlorophenol (TCP) and 2,4,5-crichIorophenoxyacetic acid (2,4,5-T). ADDRESSES: Centre fo r Chemical W orkers' Health. Hamburg Departm ent of H ealth (Pro! A. Manz, MO, 0. Flesch-Janys, H. Waltsgott): Institute fo r M athem atics and Com puter Science in Medicine. University Hospital Eppendorf, Hamburg, Germany (Prof J. Berger. PhD, S. Nagel. MO): and D epartm ent of Preventive Medicine. Institute fo r Prevention Reseerch. Alhambra. Califocnia. USA (J. H. Dwyer. PhD). Correspondence to Prof Dr med A. Manz. Beratungsstelle fr Chemiearbeiter, Fuhlsbttler Strasse 401. D-2000 Hamburg 60. Germany. 3981 P- 960 THE LANCET VOL 338: OCT 19, 1991 TABLE I-- V IT A L STATUS BY EXPOSURE G ROUPS Exposure group Vital status 1 11 m Total Men Unknown 10 (2-1%) 22 (35% ) Known alive 349 ( 74-4%) 442 (69 5%) Dead 110 (23-5%) 172 (27-0%) 3 (33% ) 46 (58-2%) 30 (38 0%) 35 (30% ) 836 (70-6%) 313 (26-4%) Total 469 139-6%! 636(53-7%) Women Unknown 10 (38% ) Known alive 24(33-9% ) 215 (811% ) Dead 1 (1 1 1 % ) 40 (151% ) 79 (6-7%) 1184 (100-0%) 1 (09% ) 11 (28% ) 95 (88-8%) 334 (83 7%) 11 (10-3%) 54 (135% ) Total 27 (6-8%) 265 (66 4%) 107 (26-8%) 399 ( 100 0%) M aterials and m ethods Chem ical plant Public concern over potential hazards from disposal o f waste products contaminated with T C D D and other higher chlorinated dioxins led to closure, on June 18, 1984, o f a chemical plant in Ham burg-Moorfleet operated by Boehringer-Ingelheim. Production o f herbicides began in late 1951. These products included 2 ,4 ,5 -T , hexachlorocyclohexane (H C H ), and lindane. Other products of the plant included dichlorobtomophenol and opioids. Synthesis o f 2 ,4 ,5 -T was based upon T C P supplied by a plant in Ingelheim. In response to an outbreak of chloracne in 1954, production o f T C P and 2 ,4 ,5 -T was halted. T C P and 2 ,4 ,5 -T production were resumed in 1957. Resumption o f T C P production was made feasible by a new process that reduced the production o f T C D D which, in the meantime, had been identified as a cause of chloracne. C o h o rt T h e cohort studied consists o f all regular employees at the Ham burg-Moorfleet plant who worked under contract with Boehringer-Ingelheim for at least 3 months during the period Jan 1, 1952, to Dec 31, 1984. Temporary or casual workers were not included because o f lack o f complete information concerning their identity, even though they m ight have experienced high level acute exposures during clean-up operations. Cohort members were identified from company personnel and union election records, and from employees identified in that way. M ortality fo llow -up Community registries o f inhabitants throughout West Germany were used to determine the vital status o f cohort members in 1989. Causes o f death were derived from medical records. W hen no medical records were available, death certificates and information from next o f kin were used. A n experienced nosologist assigned the underlying cause o f death according to W H O criteria in the 9th revision o f the International Classification o f Disease (IC D ). A ll deaths attributed to malignant neoplasms were classified on the basis o f medical records. TC D D exposure Assessment o f exposure to T C D D was based on an analysis o f production processes. T C D D concentrations were measured in nonsystematic samples o f precursor materials, products, waste, and soil from the grounds o f the plant, mainly after the plant had dosed in 1984. " These indicated T C D D concentrations up to 60 mg/kg in waste from the production of 2 ,4 ,5 -T . On the basis o f this information workers were classified as having had high, medium, or low exposure according to the production departments where they had worked. T h e numbers were: group 1 (high) 496, group 2 (medium) 901, and group 3 (low) 186. Th e validity o f these categories was evaluated by analysis o f T C D D in adipose tissue from 48 unselected members o f the cohort, who volunteered for tests done at the University o f M ainz in 1985 (P rof J. Konietzko, personal communication; see also Beck et al17). T C D D levels, in ng/kg, averaged 296 (S D 479, median 137) in 37 TABLE II-- CAUSES OF DEATH - Observed death Cause of death known Malignant neoplasms Other natural causes Unnatural causes Accident Suicide Other ICO 140-208 240-799 E800-999 Men 313 308 (100%) 93 (30-2%) 172 (55-8%) 43 (14-0%) 20 (6-5%) 22(7-1%) 1 (0-4%) Women 54 52 (100%) 20 (38-2% ) 28 (53-8%) 4 (7 7%) 2 (3 9%) 2(3-9%) 0 volunteers in group 1 compared with 83 (S D 73, median 60) for 11 in groups 2 and 3 combined. T h e median in groups 2 and 3 is higher than the " background" levels o f 7-20 ng/kg reported for unexposed persons.17 T C D D levels in 5 workers in group 1 were below 20, suggesting the possibility of misclassification error, such an error would attenuate any associations between measured exposure and cancer risk. Chloracne as a marker for T C D D exposurcJ,aB-17 was-not used here because information about chloracne in the Boehringer cohort was too incomplete. Chloracne may be fairly specific for T C D D , but it is not very sensitive: Beck et al17found that only 10 (2 8 % ) o f those workers from the Boehringer cohort with adipose levels o f T C D D exceeding 20 parts per 10u had a history o f chloracne. T w o other variables expected to be related to T C D D exposure are duration o f employment at the plant (less than 20, 20 or more years) and year in which employment began (1954 or earlier for it is presumed that those starting work before 1955 would have had higher levels o f T C D D exposure). Com parison groups Studies w ith national or regional mortality data as a reference suffer from the " healthy worker" effect-- the tendency o f cohorts o f industrial workers to have a lower risk o f early mortality due to cancer and heart disease than the general population. In this study national mortality data were augmented with a second comparison group selected a priori-- namely, 3417 male workers at the Ham burg gas supply company, used as controls in a cohort study o f furnace workers. This cohort was investigated by some o f us," using the same methods to assess vital status and cause o f death as with the Boehringer cohort. T h e follow-up covered the years 1900-85, but was restricted to 1952-85 for comparison with the Boehringer cohort. Amongst the 3120 male workers 1220 deaths were recorded. T h e follow-up period for the Boehringer cohort was also restricted to 1985. T h e two cohorts differ in that gas workers had to have worked for at least 10 years to be included while only 3 months o f employment were required for the Boehringer cohort. Th ere is no indication o f substantial differences in social status between the two cohorts. R eview o f m ed ical records 160 medical records from the Boehringer cohort (including 115 cases w ith a malignant neoplasm at time o f death) and 111 medical records from cancer cases o f the control group were reviewed by two pathologists, who did not know the cohort status o f the cases. Statistical m ethods S M R were calculated by the person-year method.71 Expected deaths were computed by applying the observed age, calendar year, TABLE III-- SOURCES OF DIAGNOSIS (M A LIG N A N T NEOPLASMS AN D OTHER CAUSES) Source Other causes Necropsy, histology Clinical report Physician report Other Total 62 (25-1%) 85 (34-4%) 54 (21-9%) 46 08-6% ) 247 (68-6%) Malignant neoplasms 69 (61-1%) 32 (28-3%) 12 00-6% ) -- (0-0%) 113 (3I`4%) Total 131 (36-4%) 117 (32-5%) 66 (18-3%) 46 (12-8%) 360* (100-0%) Deceased with known causes. 3982 O- VOL 338: OCT 19, 1991 THE LANCET 961 TABLE IV-- STANDARDISED MORTALITY RATIOS (MEN. ALL CAUSES) WITH WEST GERMAN NATIONAL DATA ANO GAS WORKERS AS REFERENCES Group West German reference No 0 E SMR Gas workers' reference' 0E SMR Total Entry $ 1954 Entry > 1954 Employment <20yr Employment > 20 yr 1148 296 852 1030 118 313 312-8 123 131-5 190 181-2 279 277 0 34 35-7 100(0-89-1-12) 0-94 (0-78-1-12) 105 (0-91-1-21) 1-01(0 89-1-13) 0-95 (0-66-1-33) 249 186-2 102 30-2 147 106-0 227 164-9 22 21-3 1-3-4 (1 IS--1-51) 1-27(1 04-1-54) 1 39(1 17-1 63) 1 380-2&-1-57) 103 (0-65-1-56) N o * nu m b er o f m en; 0 observed: E - expected; S M R - standardised m o rtality ratio {w ith 95 % C l). In com parison w ith gas w orkers B oehringer c o h o rt w a s restricted to 1 9 8 5 . sex, and cause specific mortality rates o f the gas workers or rates for West Germany to the person-years o f the Boehringer cohort. National mortality data were available from the Federal Office of Statistics for most malignant neoplasms o f interest, though for some only since 1965. 95% confidence intervals (C l) were calculated assuming the Poisson distribution. T h e program used for calculations was developed at the Institute o f Mathematics and Computer Science, University Hospital Eppendorf, Hamburg. R e s u lts T he Boehringer cohort included 1184 men and 399 women (table I)- N o company records could be located for 39 men and 14 women identified from union registers or by interview with cohort members. In this group 8 deaths in men and 2 in women were recorded. The date o f birth was not available for 1 person. Vital status was determined for 1537 persons (97-1%) by 1989. 367 deaths were documented (313 men, 54 women; table II) . For 7 cases (1-9%) causes o f death remained unknown. Table I I I shows the distribution o f sources of diagnosis. T h e reviewing pathologists confirmed malignant neoplasm as the underling cause o f death in 111 cases (91 men, 20 women). 1 death out o f 111 records o f the gas worker group was not attributed to cancer. 2 additional cases, confirmed by necropsy, were identified after the review in the Boehringer cohort. 1 additional case o f lung cancer in a man who had died in 1958 was reported by his next o f kin, but no medical record was available. This case was not included in the statistical analysis. Thus malignant neoplasm was the underlying cause o f death in 93 men and 20 women. M ortality am ong m en Total mortality equalled that o f West Germany (SMR 100) but was higher than that in the gas worker cohort (134) (table IV). T he SMR was slighdy greater for those who began employment after 1954 than for those who began before 1955. For the men working up to 20 years SMRs were 101 and 1-38 with national and gas-worker data as reference; for the group with more than 20 years, employment SMRs were 0-95 and 1 03, respectively. Mortality due to malignant neoplasms (table v) was increased with both national (SMR 1-24) and gas-workers (SM 1-39) references. Analysis after division o f the Boehringer cohort by year o f employment entry revealed an increased SM R for all malignant neoplasms among those who entered in 1954 or earlier (SMRs 1-61 and 1-87) but not for those starting employment later. An increase in risk of cancer death was also found for employment at the plant lastjng 20 or more years, SMRs being 1-87 (West Germany) and 1-82 (gas workers). Employment duration and year of entry are highly correlated; nevertheless the cancer mortality risk was more than doubled for those men who both began employment before 1955 and worked at the plant for 20 years or more (table v). SMRs for exposure group 1 were raised (table vi); increases were also found for group 2 and group 3 but the CIs were large and included unity. The subgroup with time of entry before 1955 high exposure, and employment for 20 or more years had the greatest increase in risk: SM R (West Germany) was 3-5 (1-51, 6-90) for 8 deaths. Table v i i shows SM Rs by cancer site. For SM Rs (West Germany) there were increases for all sites except colon, but all 95% CIs include unity. In comparison with the gas workers, mortality from lung cancer (SM R 1-67), and haematopoietic cancers (2-65) were significantly increased. On the Kiel classification 6 cases of non-Hodgkin lymphoma were observed (rericulosarcoma 2, lymphosarcoma 1, chronic lymphatic leukaemia 3)-- but expected numbers for West Germany were not available. TABLE V--STANDARDISED MORTALITY RATIOS (MEN. MALIGNANT NEOPLASMS) WITH WEST GERMAN NATIONAL DATA AND GAS WORKERS AS REFERENCES Duration of employment (yr) Total cohort Duration o f employment 0-4 5-9 10-19 >20 Entry ^ 1954 CM 5-9 10-19 >20 Entry > 1954 04 5-9 *10-19 >20 No 1148 West German reference 0E SMR 93 75-2 1-24(1-00-1-52) 653 39 349 M 2 (0-80-1-53) 158 14 133 1-06(0*58-1-77) 219 22 17-4 1-27(0*79-1-92) 118 18 9-7 1-87 ( H 1-2-95) 296 51 31 6 1*61 (1-20-2*12) 157 14 118 1*19(0*65-2*00) 29 5 4-4 1*12(0*37-2-63) 35 15 7-7 1-95(1*09-3-21) 75 17 7-7 2-21 (1-29-3-53) 852 42 43-6 0-96(0-69-1-30) 496 25 23-2 l 08 (0-70-1-59) 129 9 8-8 1-02(0-47-1-94) 184 7 9-6 0-73 (0-29-1-50) 43 _________ 1 1 1-9 0-52 Gas workers1reference* OE SMR 75 53-8 1*39 (I-IO-1-75) 32 23-7 1-35 (0-93-1-91) 13 10-2 1-27(0*68-2 18) 17 12-8 1-33 (0-78-2 13) 13 7-1 1-82 (0-97-3-11) 43 23-0 1-87(1*36-2-52) 12 7-9 1-53 (0-79-2-67) 5 3-7 1 36 (0-44-3-17) 13 56 2-31 (1-23-3-95) 13 5-8 2-24(1-19-3-83) 32 30-8 l 04(0-71-1-47) 20 15 8 1-27 (0-77-1 96) 8 6-5 1-23 (0-53-2-42) 4 71 0-56 (0-15-1-43) 0 1-3 3983 y 962 THE LANCET VOL 338: OCT 19, 1991 TABLE VI-- STANDARDISED M ORTALITY RATIOS (M E N . M A LIG N A N T NEOPLASMS) B Y TC D D EXPOSURE GROUP AN D W ITH WEST GERMAN N A TIO N AL DATA AND GAS WORKERS AS REFERENCES Exposure group West German reference No 0 E SMR Gas workers' reference 0E SMR Total cohort l II III Duration o f em ploym ent <20 yt I II III Duration of em ploym ent > 20 yr I II hi Entry < 1954 I II 111 Entry > 1954 I 11 III 459 34 239 142(0-98-1-99) 613 50 45*1 1 11(0-82-1 46) 76 9 6-2 1 45 (0-66-2-75) 410 26 20-8 1-25(0-82-1-83) 551 41 39-1 1-05 (0-75-1 -42) 69 8 5-6 1 42(0-61-2-79) 49 8 3-1 2-54(1-10-5-00) 62 9 5-9 1-52(0*69-2-88) 7 1 0-6 1-78 96 18 8-5 2-11(1-25-3-34) 173 26 18-8 1-38 (0 90-2-02) 27 7 4-3 1-64(0-66-3-39) 363 16 15-4 1-04(0-59-169) 440 24 26-2 0-92 (0-59-1-36) 49 2 1-9 1-03(0-12-3-71) 29 16-3 1-78 (1-19-2-55) 39 32-6 1-20 (0-85-1-63) 7 4-8 i 45 (9-58-2-99) 22 14-0 1-57 (0-98-2-37) 32 28-2 1*13(0-78-1-60) 7 4-4 1-60 (0-64-3-29) 7 2-3 3-07 (1-24-6-33) 6 4-4 1-36(0-50-2-96) 0 0-5 16 5-7 2-77 (1-59-4-53) 22 13*7 1-61(1-10-2-44) 5 3-6 1-41 (0-46-3-28) 13 10-6 1-23 (0-65-2-10) 17 19-0 0-90(0 52-1 44) 2 13 1-57(0-19-5 67) N o death due to soft-tissue sarcoma (IC D 171) was observed. 14 0% o f deaths in men were due to unnatural causes (n = 43). There were 22 suicides, yielding an SM R of 2-29 (1-38, 3-57) with West Germany as the reference and 3-90 (2-42,5-97) with the gas workers. M ortality am ong w om en The 54 deaths in women yielded an SM R (West Germany) o f0-80 (0-60,1-05). For malignant neoplasms the SM R was 0-94 (0-58,1 -45) but only the SM R for carcinoma o f the breast was raised at 2T5 (0-98,4-09) for 9 deaths. The 4 deaths due to unnatural causes included 2 suicides. Only 6-9% o f women worked in high exposure departments. Cancer incidence 12 cases o f malignant neoplasm in living men were known at the end o f the follow-up in 1989. These were prostate, urinary bladder (2), floor o f the mouth, larynx, colon, rectum, bronchus, spinocellular carcinoma, melanoma, non-Hodgkin lymphoma, and myelo proliferative syndrome. The men with bronchial carcinoma had myeloproliferative syndrome and a urinary bladder papilloma. 8 malignant neoplasms among living women were breast (5), uterus, pancreas, and colon/sltin; in 1 case o f breast cancer additionally a carcinoma o f the skin was diagnosed. Sm oking Data on smoking were available for a non-representative group of 361 men in the Boehringer cohort. 73% were self-reported smokers. In the gas worker cohort 76% of 2860 men were smokers. Discussion Company and union records provided almost complete coverage of the cohort. This, with the mortality follow-up of 97% , makes it unlikely that there is any serious information bias in the Boehringer cohort. In cohort studies there is always the problem which control group is "best". By using gas workers w e could better control for the healthy worker effect and occupational exposure-to carcinogens. The national mortality data enabled us to-idenrify the magnitude o f risk in relation to the population and help comparison of our results with other studies. T he use o f two standards makes it less likely that the observed effects are due to uncontrolled confounding. The different inclusion criteria for the Boehringer and gas worker groups with respect to length of employment required for entry to the cohort did not seriously bias the results since restricting the comparison to Boehringer workers with duration of employment greater than 10 years did not substantially change the findings. The national data came from death certificates, whereas in the Boehringer cohort medical records were used. When 190 death certificates in the Boehringer cohort were reviewed, 54 TABLE V II-- STANDARDISED MORTALITY RATIOS (M EN. BY SITE) W ITH WEST GERMAN N A TIO N AL DATA AN D GAS WORKERS AS REFERENCES West German reference Gas workers' reference Site ICO No 0 E SMR 0E SMR Hypopharynx Oesophagus Stomach Colon Larynx Lung Skin Prostate Kidney Haematopoietic system 148 150 151 153-154 161 162 172 185 189 200-208 1148 1148 1148 1148 1148 1148 1148 1148 1148 1148 2 1-4 1-42(0-17-5*14) 3 16 1-86(0-38-5-44) 12 9-9 1 21 (0 63-2 12) 8 8-7 0-92 (0-40-1-82) 2 IO 200 (0-24-708) 30 21-3 1-41 (0-95-201) 1 0 8 1-28 7 4 . 9 . 142(0-57-2 93) 3 1-9" 1-56(0-32-4-56) 7 4-2* 1-67 (0-67-3-44) 2 06 3-23 (0-39-11-69) 10 8-9 1-11 (0-54- 206) 6 7-9 0-76(0-28- 1-66) 26 15*6 1-67(1-09- 2-44) 1 1-2 5 3-6 140(0-46- 3-27) 4 14 2-90(0-78- 7-36) 9 3-4 2-65(1-21- 503) * R efw e n c d ata available on ly since 1965. VOL 338: OCT 19, 1991 THE LANCET 963 were from cases classified as cancer deaths. In 51 there was concordance; in 3 cases the death certificates did not identify a malignant neoplasm as the underlying cause o f death. In 1 case out of 136 classified as non-cancer the death certificate mentioned "occult neoplasm" (IC D 199), whereas the study diagnosis did not. It thus appears unlikely that serious underestimation of expected deaths based on national rates21-23 is an explanation for the observed effects. T he risk o f cancer mortality was less for members o f the Boehringer cohort who began employment at the plant after 1954 than for those who began earlier. During 1951-54, high concentrations of T C D D were present as a contaminant o fTC P. In the following years the incidence of chloracne decreased, but cases continued to be reported. Thus, declining exposure to T C D D is a possible explanation of changes in risk of cancer mortality according to date o f entry. This interpretation is further supported by the absence o f any other substantial changes in production processes at the Hamburg plant after 1954. The relation between length o f employment and risk of cancer mortality is further suggestive o f a dose-response relation manifesting itself after a latency period. There were also differences in risk between exposure groups as reflected in departmental assignments. However, this was striking only in men working there for more than 20 years. T he most striking effect was in members o f exposure group 1, who entered in 1954 or earlier, and who were employed for 20 or more years. Exposure to chemicals other than T C D D also occurred in different areas o f the plant, and some of these are known or suspected carcinogens. Benzene was used extensively in the synthesis o f technical H C H , so potential exposure existed in a part o f exposure group 2. Dimethylsulphate was used as a solvent only for the production o f opioids (group 3). Manual workers were probably exposed to some extent to asbestos. However, exposure to these substances explains neither the increased mortality from all cancers nor the observed pattern of associations with T C D D exposure groups. Available data on smoking suggest chat the percentage o f smokers in the Boehringer cohort is similar to that in the gas worker control group. Thus, substantial confounding due to more smoking in the Boehringer cohort seems unlikely. The similarity of the magnitude of relations between T C D D exposure and national mortality data in the Boehringer and the U S National Institute for Occupational Safety and Health (N IO SH )14 cohorts is striking. There seems to be no healthy worker effect in either cohort. The SM R for mortality from all cancers was 115 in the N IO SH cohort and 1-24 in the Boehringer cohort (national data). N o deaths due to soft-tissue sarcoma were found in the Boehringer cohort. However, the excess in the N IO SH cohort was based upon 3 deaths in a cohort almost five times as large as the Boehringer one. We found an increase in mortality from all hematopoietic cancers. This included 3 non-Hodgkin's lymphomas (IC D 200, 202). N o detailed national mortality data on that were available but on an assumption o f 1 expected case within 100 cancer deaths24 that would be a three-fold increased risk. In the N IO SH cohort 10 were observed, yielding an SM R of 1-42 (haematopoietic) and 1-33 (NH L). The N IO SH subcohort with more than 15 years of exposure showed an SM R of 1-41 (based on 25 cases across all latency categories), which is slightly higher than that of the groups with shorter duration o f exposure. The effect in our suspected most heavily exposed subgroup (group 1 with more than 20 years of employment, SMR 2-54) is more pronounced. Neither study shows a clear linear trend with duration of exposure. Zober et alls found an increased cancer mortality in the chloracne subgroup with 20 years or more since first exposure(SMR2-01;90% CI 1-22--3-15). Even in the study of O n et al2Sthis group showed a slight elevation (1-27; 0-96-1-64). As in the N IO SH study our results show that the increase in cancer mortality is not directed at special sites. T C D D induces tumours in different organs in animals and promotes tumour formation.1-2-26-27 In women we found an increase in breast cancer mortality. In a Danish study2* in the context of herbicide exposure there was no such increase but those women were exposed mainly to 4-chloro-2-methyl-phenoxyacetic acid, which is not thought to be contaminated with T C D D . Increased risks o f suicide in cohorts potentially exposed to polychlorinated dioxins were recorded by Zober et al and Fitzgerald,29and Boyle et al30refer to three Vietnam veteran studies with slight increases in suicide rates. 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A case-control studyofnon-Hodgkin'slymphoma and the herbidde 2,4-dichlorophenoxyacedc add (2,4-D) in Eastern Nebraska. Epidemiology 1990; 1: 349-56. 8. Woods JS, Polissar L, Severson RK, Heuser LS, Kutander BG. Soft-tissue sarcoma and non-Hodgkin's lymphoma in relation to phenoxy herbidde and chlorinated phenol exposure in western Washington. J Natl Cancer Inst 1987; 78:899-910. 9. Persson B, Dahlander A, Fredriksson M , Brage N H , Ohlson CG, AxelsonO. Malignant lymphomaand occupational exposures. B rJ Ind Med 1989; 46: 516-20. 10. Pearce, N E, Sheppard RA, Smith AH, Teague CA. Non-Hodgkin'slymphoma and farming: an expanded case-control study, int J Cancer 1987; 39: 155-61. 11. Wiklund K, Dich ], Holm L. Risk of malignant lymphoma in Swedish pcstidde appliers. B r J Cancer 1987; 56: 505-08. 12. Hardell L, Johansson B, Axelson O. Epidemiological study of nasal and nasopharyngeal cancer and their relation to phenoxy add or chlorophenol exposure. Am J Ind Med 1982; 3:247-57. 13. Thiess A M , Frentzel-Beyme R, Link R. Mortality study of persons exposed todioxin inatrichlorophenol-process aeddent that occurred in 3985 O '4 0 6 l 964 THE LANGET VOL 338: OCT 19, 1991 the BASF-AG on November 17,1953. A m J IndMed \982;3 :179-89. 14. Fingerhut M A , Halpcrin WE, Marlow D A, Piadtclli LA, Honchar PA, Sweeney M H , et al. Cancer mortality in workers exposed to 2,3,7,8-tetnchlorodibenzo-p-dioxin. N EnglJ Med 1991; 199:212-18. 15. Zober A, Messerer P, Huber P. Thirty-four year mortality follow-up of BASF employees exposed to 2,3,7,8-TCDD after the 1953 accident. Ira Arch Occ Environ Health 1990; 62: 139-57. 16. Kaune A, Fiedler H , Hutzingcr O. Dioxine und Furane--Quellen, Eintrag in die Umwelt und Aufnahme durch den Menschen (Literaturstudie). Lehrstuhl fr kologische Chemie und Geochemie der Universitt, Bayreuth, 1990. 17. Beck H , Eckart K , Mathar W , Wittkowski R. Levels of PCDD's and PGDFs in adipose tissue of occupationally exposed workers. Chemosphert 1989; 18:507-16. 18. Bond GG, McLaren EA, Lipps T E , Cook RR.. Update of mortality among chemical workers with potential exposure to higher chlorinated dioxins. J Occup Med 1989; 31:121-23. 19. Zack JA, Gaffey WR. A mortality study of workers employed at the Monsanto Company plant in Nitro, West Virginia. Environ Set Res 1983; 26; 575-91. 20. Manz A, Berger J, Waltsgott H. Zur Frage des Berufskrebses bei Beschftigten der Gasindusirie--Cohortensmdie. Forschung*bericht Nr. 352 der Bundesanstalt fr Arbeitsschutz, Dortmund. Wirtschaftsverlag N W , Bremerhaven, 1983. 21. BrcslowNE, Day NE. Statistical methods in cancer research: vol 11. The design and analysis of cohort studies. ARC Set Publ 1987; 82: 1-406. 22. Hpkcr W , Burkharde H U. Validittsumexsuchungcn zur amtlichen Todesursachenstatiscik. Verh D Ces Pathol 1984; 68:431. 23. Kircher T , Nelson J, Burdo H. The autopsy as a measure of accuracy of the death certificate. N Engl J Med 1985; 313: 1263-69. 24. Johnson ES. Association between exposure to phenoxys/chlorophenols and soft-tissuesarcomasandmalignant lymphomas. Fund Appl Toxicol 1990; 14:219-34. 25. On M G , Olson RA, Cook RR, Bond GG. Cohort mortality study of chemical worker with potential exposure to higher chlorinated dioxins. J Occup Med 1987; 29:422-29. 26. Pitoc HC, Goldsworthy T , Campbell HA, Poland A. Quantitative evaluation of the promotion by 2,3,7,8-teirachlorodtbcnzo-p-dioxin of hepatocarctnogenesis from dimethylnitrosamine. Cancer Res 1980; 40: 2616-20. 27. Poland A, Palen D, Glover E. Tumour promotion by T C D D in skin of HRS/J hairless mice. Nature 1982; 300:271-73. 28. Lynge E. A follow-up ofcancer incidenceamong workers in manufacture of phenoxy herbicides in Denmark. Br J Cancer 1985; 52:259-70. 29. Fitzgerald EF, Weinstein A L, Youngblood LG r Standfast SJ, Melius JM. Health effects three years after potential exposure to the toxic contaminants of an electrical transformer fire. Arch Emir Health 1989; 44: 214-21. 30. Boyle CA, Decoufle P, O 'Brian TR . Long-term health consequences of military service in Vietnam. Epidemiol Rev 1989; 11: 1-27. Outcome in patients with subarachnoid haemorrhage and negative angiography according to pattern of haemorrhage on computed tomography G abriel J. E. Rinkel Eelco F. M. W ijdicks D jo Hasan George E. M . K ienstra Cees L. Franke L oes M . Hageman Marinus Vermeulen Jan van G ijn 15% of patients with spontaneous subarachnoid haemorrhage have normal cerebral angiograms; they fare better than patients with demonstrated aneurysms, though rebleeding and cerebral ischaemia can still occur. In patients with a normal angiogram and accumulation of blood in the cisterns around the midbrain-- "perimesencephalic nonaneurysmal haemorrhage"-- outcome is excellent To test the hypothesis that rebleeding and disability in angiogram-negative subarachnoid haemorrhage might be limited to those with other patterns of haemorrhage on initial computed tomography (CT), complications and long-term outcome were studied in 113 patients with angiogram-negative subarachnoid haemorrhage, admitted between January, 1983, and July, 1990. All patients were investigated with thirdgeneration CT scans within 7 2 h of the event, and with cerebral angiography. The mean follow-up period was 45 (range 6 -9 6 ) months. None of 77 patients with a perimesencephalic pattern of haemorrhage on CT died or was left disabled as a result of the haemorrhage (0% [95% confidence interval 0 -5 % ]). Among the other 36 patients, who had a blood distribution on CT indistinguishable from that in proven aneurysmal bleeds, 4 had rebleeds and 9 died or were left disabled as result of the haemorrhage (25% [14--43% ]). Thus, tw o distinct subsets of patients with angiogram-negative subarachnoid haemorrhage should be recognised. Patients with a perimesencephalic pattern of haemorrhage have an excellent prognosis. Rebleeding, cerebral ischaemia, and residual disability occur exclusively in patients with aneurysmal patterns of haemorrhage on initial CT. Repeated angiography in search of an occult aneurysm is justified only in the patients with aneurysmal patterns. Lancet 1991; 338: 964-68. Introduction More than half of patients with aneurysmal rupture die or remain severely disabled.1 Blood in the basal cisterns on computed tomography (CT) strongly suggests aneurysmal rupture,2but the cause of the bleed remains uncertain until it is confirmed by cerebral angiography. Despite substantial improvements in imaging acquisition, angiography fails to show an aneurysm in 15% o f patients with spontaneous subarachnoid haemorrhage.13'7 It is widely believed that patients with angiogram-negative subarachnoid haemorrhage have a more favourable prognosis than those with positive angiograms. Nevertheless, they may suffer fatal rebleeds and long-term disability.3343'10. ADDRESSES: U niversity Departm ents o f Neurology. Utrecht (G. J. E. Rinkel. M D . E. F. M. Wijdicks. M O . Prof J. van Gijn. m o ), and R otterd am (D. Hasan. M O , Prof M. Vermeulen. M O ) ; University Departm ent of Neurosurgery, Academic Medical Centre. Am sterdam (L M. Hageman. M O ) : and Departm ents of Neurology. S t Elisabeth Hospital. Tilburg (G. E. M. Kienstra. M O ), and De W ever Hospital. Hearten, the Netherlands (C. L. Franke. M O ) . Correspondence to Dr Gabriel J. E. Rinkel. University Department of Neurology, Heidelberglaan 100. 3584 CX Utrecht, the Netherlands. 3986 VOL 338: OCT 19, 1991 THE LANCET 965 In 1985 we reported the existence o f a variant of subarachnoid haemorrhage characterised by a normal angiogram and focal clots in the cisterns around the midbrain on C T , which we called perimesencephalic non-aneurysmal haemorrhage." In a small preliminary study the outcome for these patients was excellent." This finding prompted us to reconsider the whole group of patients with angiogram-negative subarachnoid haemorrhage in relation to the patterns o f haemorrhage on initial C T scan. We postulated that patients with other than perimesencephalic patterns o f haemorrhage in the basal cisterns might be susceptible to rebleeding, cerebral ischaemia, and residual disability. We describe here the outcome for a large series of patients with and without a perimesencephalic pattern o f haemorrhage on CT. Patients and methods W e studied a consecutive series o f padents with subarachnoid haemorrhage and negative angiography, admitted between January, 1983, and July, 1990, to ten teaching hospitals in the Netherlands. T h is period was selected to include only patients investigated with third-generation C T scanners and to allow a m inimum follow-up period o f 6 months. 37 o f the patients, with perimesencephalic haemorrhage only, were included in a preliminary follow-up study." Inclusion criteria for this study were: third-generation C T scanning done within 72 h o f the first symptoms with evidence of subarachnoid blood; and a selective four-vessel angiogram with oblique views, magnifications, and subtractions judged normal by both the radiologist and clinician (neurologist, neurosurgeon, or both). Fig 1-- Non-contrast-enhanced CT scans showing tw o patterns o f haemorrhage on CT. Upper perimesencephalic pattern of haemorrhage, with accumulation of subarachnoid blood in cistern around midbrain (interpeduncular, ambient, and suprasellar cisterns). Lower aneurysmal pattern of haemorrhage, with subarachnoid blood in cisterns around midbrain and also in anterior interhemispheric fissure and both sylvian fissures. FoSow-up (mo) Fig 2--Period of foltow -up in 36 patients w ih aneurysmal pattern and 77 patients w ith perimesencephalic pattern of haemorrhage on CT. Before evaluation o f the outcome of the patients, all C T scans were classified by one o f us (G - J. E. R.). T h e amount of subarachnoid blood on C T was graded for each o f the ten basal cisterns and fissures (anterior interhemispheric fissure, quadrigeminal astern, the paired suprasellar cisterns, ambient cisterns, basal sylvian fissures, and lateral sylvian fissures), on a semiquantiiative scale: 0 = n o blood; 1 " small amount o f blood; 2 = moderately filled with blood; 3 - completely filled with blood. T h e density o f the clot was not measured. Clots that had expanded the original size o f a astern or fissue were graded as 3. T h e total amount o f subarachnoid blood (sum score) was calculated by adding the ten scores; the sum could therefore range from 0 to 30." T h e criteria for a perimesencephalic pattern o f haemorrhage were: centre o f the bleeding located immediately anterior to the midbrain, w ith or without extension o f blood to the anterior part o f the ambient cistern or to the basal part o f the sylvian fissure; no extension to the anterior interhemispheric fissure and no extension to the lateral sylvian fissue, except for a small amount o f blood (grade 1); and absence o f frank intraventricular haemorrhage." As a linear measurement o fventricular size, we used the bicaudate index, which is the width o f the frontal horns at the levels o f the caudate nuclei divided by the corresponding diameter o f the brain. W e converted the bicaudate index into a relative size by dividing the absolute values by the upper lim it for age as described previously." T h e inhospital course o f some o f the patients with perimesencephalic haemorrhage has been described elsewhere." T h e outcome was assessed according to the Glasgow outcome scale." Patients were interviewed by telephone, seen as outpatients, or visited at their homes. T h e interview included questions about recurrent episodes o f sudden severe headache, quality o f life, and level o f performance. In a few cases the information was obtained through the general practitioner i f he or she advised against contacting the patient. Results We studied 113 patients with angiogiam-negarive subarachnoid haemorrhage who met the inclusion criteria. The C T scan showed a perimesencephalic pattern of haemorrhage in 77 patients (fig 1). T he asternal blood distribution of the remaining 36 patients was indistinguishable from C T patterns in patients with a proven aneurysmal bleed (aneurysmal pattern; fig 1). In 2 of these patients the C T scan also showed an intracerebral haematoma. Angiography was repeated in 7 patients with a perimesencephalic pattern, and in 15 patients with an aneurysmal pattern of haemorrhage. T he mean age was 51 years for both groups of patients. T he mean period of follow-up was 45 (range 12-90) months in the perimesencephalic group and 44 (6-96) in the aneurysmal group (fig 2). N o patient was lost to follow-up. The clinical and C T features of the two groups are listed in table I. I 3987 > 'V 0 S 3 viii THE LANCET VOL 338: OCT 19, 1991 Abridged Prescribing information SABRIlY Tablets P re s e n ta tio n : W hite tablets with b raakline m arked S A 8 R IL each containing SOOmg vigaDairin. Usee: lndic3 i>aoT Treatm ent of eoileosy not controlled by o ther am iepileptic drugs. D o s a g e e n d A d m in is tra tio n : O ra l administration o n ce o r twice daily added to the patient's current therapeutic regimen. Adults: R eco m m en d ed starting dose 2gfday In creased or d ec rea se d in Q.Sg or t ,0g increm ents depending upon dim cai response and toieraoiiity Mam m um ag /da y.T he re >s no direct correlation b etw een p la sm a concentration and efficacy. ChiUesn: R ecom m en ded s ta rin g dose ig rd a y in ag es 3 *9 y ears and 2g /day if older. Ektorty: C on sid er d o se reduction in patients w ith im paired renal function. C o n tra in d ica tio n s, Precautions, W arnings etc U s* tn p regnancy a n d lactation: C ontra indica ted. P n cau t& ts: Abrupt withdraw al m ay lead to rebo u n d seizures.C aution in p atients w ith history of psychosis o r behavioural problem s.Caution m etderty patients, particularly c reatinine d e a ra n c o below 60m l/m in. R ed u ce d o se and monitor d o se fy for ad v ers e events. W arnings: Vigabatrin c a u ses intramyetinic o e d e m a in the brain w hite m atter tracts of anim als but there is no evidence of tins in m an. H owever, monitor patisnts for neurological changes. S e e the M product d ata sheet. Enacts on dnytng afrttify.- Drowsin ess h as b e e n s e en a n d p atients should be w arned. S id * effects: Are mainly C N S related. Aggression and psychosis h av e b een reported a n d a previous history of psychosis o r a behavioural problem ap p ears to b e a predisposing factor. O th er reported events: drowsiness a n d fatigue, d im n e s s , nervousness, imtabiirty. depression, head ach e and less comm only confusion, memory disturbance and m io n complaints: also w eight g ain an d m inor gastrointestinal side-effects. Also m children ex ata no n and agilation.Som e patients m ay e xp erien ce an in crease in seizure frequency w ith v igabalnn. particularly those with myoclonic seizures.Tests have not revealed evidence of neurotoxicity m hum ans.Lab d a ta do not indicate renal or h epatic toxidty. D ecreases in S G O T a n d S G P T h ave b ee n o b served. C hronic treatm ent m a y lead to a slight d ecrease m haemoglobin. Drug interactions: A re unlikely. A gradual reduction o< about 2 0 % in p lasm a p henytom concentration has b ee n observed. N o dirncafly significant interactions with carbam azepine. phenobarM one or sodium valproate. Legal C ategory: POM P a c k a g e Q u a n titie s : Bfister stnps of 1 0 in ca n o n s of 100. Product Licen ce N u m b e r PL 442S/0098 N H S Price: 46.00 D ate o f Preparations: November 1990. You must refer to the fun prescnbmg information before administenng Sabril. Further information including fuH product d ata s h e et is available from (he Licence Holder: Merreff D o w P harm aceuticals Ltd. Lakeside H o u se. Slockle y Park, Uxbridge. M iddlesex. U B 11 i BE 1. Mumtord JP Br j Clin Pract i960: 42 (S u p o i6l): 7-9 nuM M AW S.-S MERRELL DOW NEW BOOKS FROM JOHNS HOPKINS THE GUIDETO LIVINGWITH HIVINFECTION Developed at the Johns Hopkins AIDS Clinic John G. Bartlett, M.D., and Ann K. Finkbeiner "Invaluable, enlightening and nonjudgmental."-- David Perlman, San Francisco Chronicle 11.50 paperback ERYTHROPOIETIN Molecular, Cellular, and Clinical Biology edited by Allan J. Erslev, M.D., John W. Adamson, M.D., Joseph W. Eschbach, Jr., M.D., and Christopher G. Winearls, M.B., Ch.B., D.Phil. Leading researchers and clinicians offer a complete and up-to-date summary of the physiology and clinical action of erythropoietin. AGING AND ENVIRONMENTAL TOXICOLOGY Biological and Behavioral Perspectives edited by Ralph L. Cooper, Jerome M. Goldman, and Thomas J. Harbin Explores the interaction between exposure to environmental hazards and the reduced adaptive capabilities of the elderly. 46.50 hardcover INDOOR AIR POLLUTION A Health Perspective Jonathan M. Samet, M.D., M.S., and John D. Spengler, Ph.D., M.S. Contributors discuss methodologies used in measuring exposures to pollution, strategies for improving indoor air quality, and other issues. 18.00 paperback REGIONAL ANTINEOPLASTIC DRUG DELIVERY INTHE MANAGEMENTOF MALIGNANT DISEASE Maurie Markman, M.D. Offers an overview of the rationale, problems, and clinical results of regional drug therapy. 36.00 hardcover MILESTONES IN LEUKEMIA RESEARCH ANDTHERAPY Emil J Freireich, M.D., and Noreen A. Lemak, M.D. The first book to offer a comprehensive history of the subject covers the etiology, therapy, and genetics of the disease. 43.00 hardcover 53.00 hardcover THEJOHNS HOPKINS UNIVERSITY PRESS Distributed in the U.K. by Plymbridge 9 3988 O -H O H 4 // 3989 D -yosTf, // THE LANCET Vol 338 Saturday 26 October 1991 ORIGINAL ARTICLES No 8774 I Cancer m ortality in workers exposed to chlorophenoxy herbicides and chlorophenols I Ro d o lfo Saracci M a nolis Kogevinas Pier-A lberto Bertazzi Bas H . Bu e n o d e M e sq u it a D avid Co g g o n L o is M . G r e e n T im o K a u p p in e n K r is t a n a . L 'AbbE Margareta L itto rin Elsebeth Lynge John D. M athew s M anfred N euberger John O sman N eil Pearce Reg in a W inkelm ann Epidemiological studies have revealed an increased riskof cancer, notably soft-tissuesarcomas and non-Hodgkin's lymphomas, in people occupationally exposed to chlorophenoxy herbicides, including those contaminated by 2, 3, 7 ,8-tetrachlorodibenzo-p-dioxin (TCDD). We report here a historical cohort study of mortality in an international register of 18 910 production workers or sprayers from ten countries. Exposure was reconstructed through questionnaires, factory or spraying records, and job histories. Cause-specific national death rates were used as reference. No excess was observed in all-cause mortality, for all neoplasms, for the most common epithelial cancers, or for lymphomas. A statistically non-significant two-fold excess risk, based on 4 observed deaths, was noted for softtissue sarcoma with a standardised mortality ratio (SMR) of 196 and 95% confidence interval (Cl) 53-502; this was concentrated as a six-fold statisticallysignificant excess, occurring 10-19 years from first exposure in the cohort as a whole (SMR = 606 [165-1552]) and, for the same time period, as a nine-fold excess among sprayers (SM R=882 [182-2579]). Risks appeared to be increased for cancers of the testicle, thyroid, other endocrine glands, and nose and nasal cavity, based on small numbers of deaths. The excess of soft-tissue sarcomas among sprayers is compatible sjrith a causal role of chlorophenoxy herbicides' but the excess does not seem to be specifically associated with those herbicides probably contaminated by TCDD. Lancet 1991; 338:1027-32. Introduction Chlorophenoxy herbicides have been used extensively since the mid-1950s for control of weeds and for removing unwanted brush on non-crop land.1 In the 1960s an equal mixture of 2,4-dichloro and 2,4,5-trichloro phenoxyacetic adds (agent orange) was heavily used in South Vietnam and Cambodia for defoliation by the US armed forces. Since 1969 in several industrialised countries, production and use of some compounds, and especially of 2,4,5trichiorophenoxyacetic add (2,4,5-T) and its derivatives have been reduced or banned. Chlorinated phenols are ADDRESSES: U n it o f A nalytical Epidem iology. In ternatio nal A g e n c y fo r R esearch o n C a n c e r. Lyon, F ra n c e (R. Saracci. M O. M . Kogevinas. PhD, R Winkelmann. M A ); U n iv e rs ity o f M ila n . Ita ly (Prof P. A. 8ertazzi, M O ): N a tio n a l In s titu te o f P u b lic H e a lth a nd E nviron m ental P ro te ctio n . B ilth o v en . N eth erla n d s (B. H. Bueno de Mesquita. M O ): M e d ic a l R esearch C oun cil E nviron m ental Epidem iology U n it. U niversity o f S ou tham p ton. U K (D. Coggon, M O ): O n ta r io H y d ro . T o ro n to . C a n a d a ( L M . Green. C P H ); In stitu te o f O ccupational H ealth . H elsinki, Finland (T. Kauppinen, PhD): D e p a r tm e n t o f P re v e n tiv e M e d ic in e a nd B io s ta tis tic s . U n iv e rs ity o f T o ro n to , C an ad a (K. A. L'Abb. PhD); Lund U n iv e rs ity , S w e d e n (M . Littorin. M O ); D a n is h C a n c e r R e g is try , C o p e n h ag en . D e n m a rk (E. Lynge. PhO); M e n z ie s S c h o o l o f H e a lth R es e a rc h . C a s u a rin a . A u s tra lia (Prof J. D. Mathews. M O ); In s titu te o f E nviron m ental H ygiene. V ie n n a. A u s tria (Prof M . Neuberger. M O ); H e a lth and S a fe ty E x e c u tiv e . B o o tle. M erseysid e. UK (J. Osman, M O ); W e llin g to n S ch o o l o f M e d ic in e . N e w Ze a la n d (N . Pearce. PhO). Correspondence to Dr Rodolfo Saracci. Unit of Analytical Epidemiology. International Agency for Research on Cancer. 1SO cours Albert Thomas. Lyon 69372. Cdex 08. France. i I ,l !f. ii-; Q Q DO )- intermediates in the production of these chlorophenoxy herbicides and are also used directly for wood preservation. Both groups ofcompounds may be contaminated during the production process with polychlorinated dioxins and furans, including tetrachlorodibenzo-p-dioxin (dioxin, TCDD), which is a widespread contaminant of the general environment.1 Studies of cancer risks have revealed excesses for soft-tissue sarcoma and non-Hodgkin's lymphoma in populations exposed to chlorophenoxy herbicides, chlorinated phenols, dioxins, and furans during manufacture and spraying or after accidents.1"" In 1987 an International Agency for Research on Cancer (IARC) working group concluded that there was "limited" evidence ofhuman carcinogenicity for chlorophenoxy herbicides and chlorinated phenols.17 A recent paper," focusing on exposure in chemical plants to "dioxin", reported excesses for cancer of the respiratory tract and soft-tissue sarcoma, but could not exclude the contributionofsmoking rnd other exposures in the workplace. We present here the first detailed mortality analysis of a large international cohort of workers (the International Register of Workers Exposed to Phenoxy Herbicides and their Contaminants) set up by the IARC in association with the US National Institute of Environmental Health Sciences (NEEHS). Results for some cohorts in the registerhave been reported earlier'1" -13but for different follow-up periods. M aterial and methods Study population T he register incorporates information on 17 372 male workers, 1537 female workers, and 1 o f unknown sex, distributed among twenty cohorts from ten countries (table I). Since publication o f the register population" minor corrections have led to the exclusion of 62 workers found to be ineligible. Workers from one British company which both produced and sprayed herbicides have been separated.here into two cohorts (14 and 20). The register includes workers ever employed in production or spraying, except in the cohorts from Australia, Canada, and New Zealand, in which minimum employment periods o f 1 year, 6 months, and 1 month, respectively, were specified. Eligibility of cohorts depended on the completeness at company level of records identifying workers and on the ability to ensure tracing rates o f 95% or mote. Follow-up for mortality was based either on computerised national record systems or on active follow-up procedures. Additional information on cases o f soft-tissue sarcoma and non-Hodgkin's lymphoma cases was sought from medical records and cancer registries. Denmark, New Zealand, Finland, and Sweden provided incidence data from population-based cancer registries. Person-years at risk were calculated from 1955 onwards since only from that year were cancer-spedfic mortality rates available for all participating countries. Excluded from the analysis were 220 workers who either died or were lost to follow-up before 1955, 105 workers with unknown year of first exposure, 131 with unknown year o f birth, 1 with unknown sex, and 63 with other missing information. The 18 390 workers included comprise 16 863 males and 1527 females, and 307 488 person-years at risk were accumulated, with an average follow-up o f 17 years. Workers lost to follow-up constituted 5% o f the total cohort, and in no individual cohort did this proportion exceed 10%. Exposure assessment Questionnaires were constructed for factories producing chlorophenoxy herbicides or chlorinated phenols and for spraying cohorts. These were completed with the assistance of industrial hygienists, workers, and/or factory personnel. Industry and other production records were also used. Job histories were examined when available. Workers were classified as exposed, probably exposed, exposure unknown, or non-exposed: TA 8 L E I-- D E S C R IP TIO N OF COHORTS IN IN TER N ATIO N A L REGISTER Cohort No Type of of subjects cohort Sex Period at risk Main chemicals sprayed or produced 1, Australia 2, Austria 2177 159 3, Canada 4, Denmark* 1222 3843 5, Denmark 6, Finland 7, Italy 8, Italy 9, Netherlands 10 Netherlands 11, N ew Zealand 616 62 325 81 1167 1143 1038 12, N ew Zealand 13, Sweden 780 270 14, U K * 15, U K 16, U K 1531 145 1147 17, U K 18, U K 19. U K 20, U K 353 275 528 2013 s M 1955-83 2,4,5-T/2,4-D PC B 1971-S8 2,4,5-T/2,4-D M C P A /2,4,5 -T C P 2,4-DCP s M 1955-82 2,4,5-T/2,4-D p B 1955-82 M C P A /M C P P 2,4-DP p B 1955-82 2,4-D P /M C P A p B 1955-85 23,4,6-TcCP p B 1970-86 2,4,5-TCP p B 1967-86 2,4 -D /M C P A p B 1955-85 2,4,5-172,4,5-TC P p B 1965-86 M C P A /M C P P /2.4 -D p B 1969-87 Z 4 - T /2 .4 - D M C P A /M C P B / 2,4,5-TCP s B 1973-87 2,4,5-T /M C P A /2 ,4 -D p B 1965-86 2 ,4 -D /M C P A /M C P F 2,4,6-TCP p M 1955-87 M C P A p M 1960-85 PCP p M 1975-87 2,4-D B /M C P A M CPP/2.4-D/2.4- D P Z 4.5-T p M . .t-87 MCPB/PBA p M 1969-87 2.4-DP/2.4-DB MCPA/M CPP p M 1969-87 M C P A /M C P P /2.4 -D 2,4-DP s M 1955-87 M C P A i - ipfj y rc p-production: PC N o n m c a K inproduction. M -m *le c B -b o th saxes. 24-0w24-dichlorophenoxyacctic acid; 24-DP 2-(24-dichlorophenoxv)prapanaicacid: 2 4-O B " 4-(24-dichloraptenoxy)butana<c acid: 24.5 -T " (24.5nichloropiwnoxy)-acctic acid:. Z4,5-TP- 2-1Z4.5-inchkxoptwmoxY)-propanoic ext: MCPA-(4-ciila(0.2-fnethY<-pi<enoxy)-aca<ic add: MCPP-2-(4-ch!oro-2fnathyt-phenoxYlpropanoic add: MGPB-4-(4-chloro-2*methYl-phenoxy) butanoic add: Z4-0CPZ4-dichkxopbenor; Z4J5-TCP.Z4.5-triclilotophenol; Z4.6-TCP-Z4.6-tricMaroptwnoL- 23.4.6.TCP-23.4.6-trachlorophenol: PCP-pmuachlocophcnoL PBA-phenoxvbutyricadd. *35additional subjectsfrom Ocnmarfc andtheUnited Kingdomwereexposedduring both production and spraying. tPormulators and packers- 1382-87: handymen-1967-87: -process worta n - 1363-87. E xposed w orkers (n = 13482) comprise all known to have sprayed chlorophenoxy herbicides and allwho had worked in any of the following departments at factories producing chlorophenoxy herbicides or chlorinated phenols: synthesis, finishing, formulation, packing, maintenance/repair, laboratory, chemical effluent/waste, cleaning, shipping/transportatioo/stotes/warehouse, plant supervision, cleaning during accident, and other and unclassified exposure. Probably exp o sed workers (n=416) comprise all workers in cohorts 15 and 18; no job titles were available but it was judged that most workers would have been exposed. (Exposed and probably exposed are aggregated for some analyses, as indicated in the tact.) Workers w ith unknow n exposureip=541) had no information on exposure status. N o n -e x p o se d workers (n = 3951) w o e those never employed in the parts of factories which produced chlorophenoxy herbicides or chlorinated phenols and who never sprayed chlorophenoxy herbicides came mainly from Australia, Denmark, Netherlands, New Zealand, and U K (224, 1966, 1283, 214, and 180, respectively). Although not exposed to chlorophaioxy herbicides they were exposed to other chemicals, such as dyes and rodentiddes. Workers were also categorised as producers (12 492) and sprayers (5898). Exposed and probably exposed workers were also classified by groups o f chemicals produced or sprayed (9377 chlorophenoxy herbiddes, 408 chlorinated phenols, and 4113 both) and within the manufacturing cohorts by department(3034 main production, 1522 I 3991 S -H o ' 'l 1 VOL 338: OCT 26, 1991 -- THE LANCET 1029 TABLE 11-- M O R TA LITY BY DETAILED CAUSE ANO EXPOSURE TO CHLOROPHENO XY HERBICIDES A N D /O R CHLOROPHENOLS, BOTH SEXES Cause of death (IC O 8) Exposed AH causes Malignant neoplasm s (1 4 0 -2 0 7 ) Buccal cavity and pharynx (140-149) Oesophagus (150) Stomach (151) Intestine, except rectum (152-153) Rectum (154) Liver, gallbladder and bileduct (155-156) Pancreas (157) Peritoneum (158) Unspecified digestive organs (159) Nose & nasal cavities (160) Larynx(161) Trachea, brondtus and lung (162) Connective and ocher soft tissue (1 7 1) Skin (172-173) Male breast (174) Female breast (174) Female genital organs (180-184) Prostate (185) Testis (186) Bladder (188) Kidney (189) Brain (191-192) Thyroid gland (193) Other endocrine gland (194) IU-defined sites (195,199) Lymphosarcoma (200,202) Hodgkins disease (201) Multiple myeloma (203). Leukaemia and alcukacnua (204-207) Benign and unspecified neoplasms (210-239) Circulatory system (3 3 0 -4 5 8 ) Respirator/ system (460-519) Accidents, poisonings, violence (E80Q-E999) Unknown causes 92* (88-96) (I87C) 101 (92-110) (499) 1 1 6 (5 8 -2 0 7 )///) 6 0 (2 6 -1 1 9 )/ ) 89(64-121) (40) 113(81-154)(41) 110(70-163) (24) 44(12-113) (4) 112(73-164) (26) 156(19-564) (2) 331 (96-846) (4 ) 291(60-851) (3) 145 (63-285) / ) 102(87-118) (173) 201 (55-515) (4) 32* (7-94) (3) 345 (42-1246) (2 ) 3 0 (1 -1 6 6 )//) 94(19-274) (3) 111 (75-158) (30) 225(96-464) (7) 80(42-136) / 13) 9 7(4 8-173)///) 38* (14-82) (6) y 367(100-940)/-#) 462(95-1349) f j ) 131 (83-197) (23) 9 7 (4 8 -1 7 3 )///) 39(5-141) (2) 69(19-178) (4) 1 1 7 (7 0 -1 8 6 )// ) 199* (103-348) (12) 90* (84-97) /J7) 72* (60-86)//2 5 ) 100 (86-116) (174) -- (SO) p<0-05. S M R (95% C l) (no of observed deaths) Probably exposed Non-exposed 122(93-158) (58) 129(74-210) (16) 0 (0-1942) (0) 0(0-971) (0) 0(0-305) (0) 0(0-479) (0) 1 7 9 (5 -9 9 5 )//) 0(0-2170) (0) 185(5-1032) / / ) 0(0-12 296) (0) 0 (0-12 296) (0) 0(0-12296) (0) 0(0-3074) (0) 221* (1 1 0 -3 9 5 )///) 0 (0-7378) (0) 0(0-2838) (0) - -0 (0 -3 6 889) (0 ) -- 0(0-671) (0) 0(0-5270) (0) 227(6-1266) / / ) 0(0-1537) (0) 0 (0-1025) (0) 0(0-12 296) (0) 0(0-36889) (0) 0 (0-802) (0) 0 (0-1476) (0) 769 (19-4286) / / ) 0 (0-2838) (0) 0(0-1118) (0) 0(0-2459) (0) 1.11 (7 2 -1 6 5 )/ Z ) 95 (31-221) (5) 169 (55-394) (5 ) - ( oi 03(93-114) (392) 99(81-120) (ICO) 5 9 (2 -3 3 0 )//) 255 (83-595) IS) 85 (34-175) (7) 67 (22-156) /J ) 43(5-156) (2) 83(10-300) (2) 61 (13-177) (3) 0 (0-1085) (0) 870* (105-3141) (2) 0 (0-2170) (0) 9 0(2-502)//) 140(100-190) (40) 0(0-878) (0) 144(30-422) (3) 0(0-3689) (0) 114(31-293) (4) 89(18-260) (3) 4 0 (5 -1 4 3 )/2 ) 0 (0-444) (0) 56 (7-202) (2) 3 5 (1 -1 9 7 )//) 86 (18-250) (3) 0 (0-1230) (0) 0(0-1942) (0) 153(50-357)/5 ) 178(48-455) (4) 0 (0-332) (0) 160(19-578) (2) 88(18-256) (3) 317* (103-739) (S) 9 9(8 4 -1 16 )//) 106 (6 9 -1 5 6 )/2 5 ) 108(77-146) (41) -- ( I t ) -------- Unknown 157* (119-203) (S7) 1 35 (7 2 -23 1 )/13) 667(17-3714) / / ) 0 (0-2170) (0) 0 (0-492) (0) 1 6 4 (4 -9 1 3 )//) 2 3 8 (6 -1 3 2 7 )//) 4 3 5 (1 1 -2 4 2 3 )//) 0(0-820) (0) 3333(84-18 5 7 2 )/)) 0(0-18444) (0) 0(0-36889) (0) 0(0-3074) (0) 110(23-320) (3) 0(0-12296) (0) 0 (0-2049) (0) 0(0-36889) (0) 0(0-1537) (0) 0 (0-753) (0) 2 1 7 (6 -1 2 1 1 )//) 0 (0-3074) (0) 0(0-1085) (0) 0(0-1366) (0) 556 (67-2007) (2) 0 (0-18 444) (0) 0(0-36889) (0) 3 2 3 (8 -1 7 9 7 )//) 0(0-1757) (0) 0 (0-3353) (0) 0 (0-3074) (0) 0(0-1025) (0) 0 (0-2306) (0) 1 1 3 (6 4 -1 8 3 )// ) 191 (52-490) (4 ) 319* (182-518) (16) -- (t) j ] j ; i- iI maintenance and cleaning, 1665 other, .1907 undassifiable). A substantial number of workers producing chiorophenoxy herbicides may also have exposed to chlorophenols (eg, p-chloro-ocresol) which are used as raw materials in the synthesis of chiorophenoxy adds. Exposure to the most toxic dioxin congener (2,3,7,8,-T C D D ) may occur during production o f 2,4,5-TCP and 2,4,5-T, and during spraying ofherbiades containing 2,4,5-T or its derivatives.1Factories 4,5,6,8,10,14,15,17,18, and 20(n = 6845) had drher not produced 2,4,5-T or had produced very little o f it (around 10 tonnes per year during the study period). Workers in these factories were exposed to various chiorophenoxy herbicides, chlorinated phenols, polychlorinated dibenzodioxins, and furans but were probably not exposed to T C D D . Thus within the register population it was possible to differentiate workers probably exposed to T C D D and workers probably not exposed to T C D D . Production accidents were known to have occurred in two cohorts (factories 7 and 9), 319 workers being exposed. There were 181 chloracne cases among workers in the cohort, 128 of whom came from cohort 2, which incorporated only workers diagnosed with chloracne. 9 production workers with a history of chloracne from exposure to polychlorinated dioxins in 1971-73 had a median level of 340 pg T C D D per g blood lipids (range 98-659), higher than 4 unexposed workers from the same plant (median 18, range 8-28 pg/g) and 17 external controls (median 16, range < 5 to 23 pg/g) (M. Neubcrger et al, to be published elsewhere.) Statistical analysis The person-years method was used to derive standardised mortality ratios (SMR) with 95% confidence intervals (Cl) based on the Poisson distribution." An excess or deficit of an SM R is regarded as statistically significant at p < 0-05 (two-tail) when the C l ' does not include 100. T he WHO Mortality Data Bank was used to compute national mortality reference rates for sex, age (in 5-year age groups), and calendar period (in 5-year periods, except when such a period coincides with an ICD revision). Duration o f exposure was treated as a time-dependent variable in the allocation of personyears at risk. Poisson regression analysis was applied for selected sites.30 Coding Coding of underlying cause of death was done nationally. A conversion table has been prepared in IARC to allow the pooling of results over different ICD revisions.31-33 About 40% of soft-tissue sarcomas (one of the a priori neoplasms o f interest) develop in parenchymal organs3* and are not coded under IC D 171 (8th and 9th revision, "malignant neoplasms o f connective and other soft tissue"). Histological diagnoses were not generally available and reference mortality rates are not available for sarcomas not coded as ICD 171. SMRs for soft-tissue sarcoma therefore relate only to sarcomas coded as ICD 171. Information on other sarcomas, identified from medical records and cancer registration, is presented but no statistical analysis was done. Results All-cause mortality was lower than expected from national rates (SMR = 95 [95% Cl 91-99]). Among exposed workers, this was mainly because of low mortality for circulatory and respiratory diseases (SMR=90 [84-97], SMR = 72 [60-86], respectively). Workers with unknown 3992 O - V I [ I i 1030 THELANCET VOL 338: O C T 26, 1991 TA8LE III-- MORTALITY FOR ALL M ALIG NANT NEOPLASMS A ND FOR SOFT-TISSUE SARCOMA AND NON-HOQGICINS LYM PH O M A SEPARATELY. BOTH SEXES All malignant neoplasms -- Obs Exp S M R (95% Cl) Exposure Exposed and probably exposed Non-exposed 5IS 508-85 101 (93-110) 100 10108 99(81-120) Type o f cohort* Production Sprayers 253 258-91 98(86-111) 262 249 94 105(93-118) Chemicals produced or sprayed* Both Phenoxy Chlorophenob 112 106-70 105(86-126) 384 385-28 100(90-110) 19 1682 113(68-176) TCDD exposure* Probable U n likd y 236 215-12 110(96-125) 279 293-76 95(84-107) Years since first exposure* 30 + 20-29 10-19 0-9 Duration o f exposure* (yr) 20 + 10-19 1-9 <1 Department* Production Maintenance Other exposure Unclassified 74 88-60 84(66-105) 171 159-19 107(92-125) 170 166-49 102(87-119) 100 94-53 106(86-129) 36 42-17 85(60-118) 74 7616 97(76-122) 234 230-54 102(89-115) 168 155-68 108 (92-126) 62 60-38 103(79-132) 40 4 202 95(68-130) 42 3965 106(76-143) 107 114-10 94(77-113) ` Exposed and probably exposed woricen ara grouped together. Soft-tissue sarcemas Obs Exp SMS (95% Cl) 4 204 196 33-502) 0 0-42 0 0-878) 103 97 3-541) 3 101 297 -61-868) 1 0 4 8 206 '5-1161) 3 1-50 200 41-585) 0 006 0 0-6148) 2 100 2CO 24-723) 2 104 193-23-695) 0 0-24 0 0-1537) 0 052 0 0-709) 4 0 6 6 606 166-1552) 0 0-50 0 0-738) 0 0-15 0 0-2459) 2 0-29 690 54-2491) 0 0-89 0 0-415) 2 0-59 339 -41-1125) 0 0-29 0 0-1272) 0 0-15 0 0-2459) 1 0-16 625 '16-3482) 0 0-35 0 '0-1054) Non-Hodgkin's lymphomas Obs Exp S M R (95% C l) u 11 64 95 (47-169) 4 225 178 (48-455) 8 5-36 149 (64-294) 3 6-28 49 (10-140) 4 2-37 169 (46-432) 7 8-96 78(32-161) 0 0-31 0(0-1190) 5 5-76 87(28-203) 6 5-88 102 (37-222) 2 168 119(14--430) 3 3-38 89(18-259) 5 3-94 127(41-296) 1 267 38 (1-209) I 1-02 98(3-546) 1 1-81 55(1-308) 3 5-36 56(12-164) 6 3-35 179(66-390) 2 1-40 143(17-516) 1 0-91 110(3-612) 3 0-90 333(69-974) 2 2-08 96 (12-347) exposure status had high all-cause mortality (table ii), especially for accidents, poisoning, and violence including suicide (SMR = 319 [182-518]). Table II gives SMRs (and 95% CIs) and observed deaths, for major causes of death and for malignant neoplasms by site and exposure for both sexes combined since only 10 deaths from cancer were available for analysis among exposed females. Significant excesses were observed among males for malignant thyroid and benign and unspecified neoplasms in the exposed category, m a lig n a n t neoplasms of trachea, bronchus and lung in die probably exposed category, and malignant neoplasms of unspecified digestive organs and benign and unspecified neoplasms in the non-exposed category; significant deficits were observed for malignant neoplasms of skin and of btain. Exposed workers had SMRs above 200 for neoplasms of unspecified digestive organs, neoplasms of the nose and nasal cavity, soft-tissue sarcoma, breast cancer (in males) and for neoplasms of the testis, other endocrine glands and thyroid. Table hi gives combined SMRs for exposed and probably exposed workers of both sexes, for all neoplasms, soft-tissue sarcomas and non-Hodgkin's lymphomas. The pattern of risk for all neoplasms by time first exposure did not indicatea strong healthy worker effect, and mortality did not vary substantially between the groups examined. Soft-tissue sarcoma 4 deaths were observed, all among exposed male workers (table III) . No increased risk was observed among production workers (1 death), whereas mortality appeared to be increased among sprayers (3 deaths, SMR = 297 [61-868]). All deaths occurred 10-19 years after first exposure, giving rise, for this time interval, to a six-fold excess risk in the cohort as a whole (table HI) and an even greater excess among exposed sprayers (3 deaths, SM R=882 [182-2579]). No differentiation in risk was observed in relarioa to duration of exposure or probable TCDD exposure. 5 additional cases of soft-tissue sarcoma were recorded in cohort members who were alive at the end of follow-up or who had died with a certified cause of death other than ICD 171. These included 1non-fatal case in the non-exposed group. Details of all 9 cases are given in table iv. Malignant lymphoma 14 deaths from non-Hodgkin's lymphoma (ICD 200, 202,8th and 9th revision) were observed among men and 1 among women; 11 deaths were in exposed workers, all men. Mortality for exposed/probably exposed workers was dose to expected (SMR=95) with production workers having a small statistically insignificant increase in mortality (8 deaths, SMR = 149) (table III). 10out of 11 deaths occurred more than 10 years after first exposure. 6 deaths occurred among workers exposed for than a year, and no difference in risk could be seen in relation to exposure to TCDD or type ofchemical produced. The highest SMR among production workers was for those in "other jobs" (transport/storage, laboratory workers, plant supervisors). 4 deaths from non-Hodgkin's lymphoma were observed among nonexposed workers in one Danish factory (cohort 4). Mortality for non-exposed workers was higher than that ofall exposed 3993 VOL 338: O C T 26, 1991 THE LANCET 1031 Case* Sex. age Year of deatht TABLE IV-- DESCRIPTION OF 9 CASES OF SOFT TISSUE SARCOMAS Cause of death Histology! Longest held job Years Years since first of exposure exposure 1, Australia 2, Denmark 3, Denmark 4,Ddnmaik 5, Denmark 6, New Zealand 7, New Zealand 8, U K 9, Denmark M , 46 <1980 Connective tissue lower limb (IC O 171) M , 32 <1980 Connective tissue lower limb (IC D 171) M , 34 Alive, Jan, 1984 M , 47 <1980 Ill-defined cancer M , 64 <1980 Prostate cancer M , 35 Alive, Jan ,1988 M , 55 1980 + Connective tissue upper limb (IC D 171) M , 43 <1980 Connective tissue unspecified (IC D 171) M . 56 Alive, Jan, 1984 Fibrosarcoma of the hip Sprayer Neurofibrosarcoma, lower limb Mesenchymal sarcoma (possible liposarcoma, retroperitoneum) Haemangiopericytoma, bade Leiomyosarcoma, prosate Production, transportaiion/norage Production unspecified Production tiansportation/storage Production, uansponation/storage Fibrous histiocytoma, lower limb Sprayer Neurilemmoma Spindle cell neurilemmoma! sarcoma Sprayer Sprayer Leiomyosarcoma, larynx Non-exposed 1 addition*! incident caaa occurred after the end of follow-up in New Zealand. 'Cases 2.3.4. 5.8. and 9 previously reported.2-*-' TPrecise year of death not provided for reasons of confidentiality. {Histology from cancer registration or medical records. Histology record not retrieved for case 1. 16 10 14 21 17 12 14 18 26 16 <1 <1 a 2 12 12 <1 <1 workers, and similar to chat of production workers (table til). The cases arose in seven countries. (Not included in table I I I are 3 cases in cohort members who were alive at the end of follow-up or whose certified underlying cause of death was not ICD 200 or 202.) Mortality from Hodgkin's disease was below expectation. Other neoplasms More than twofold increases in risk were noted among exposed workers for several less common neoplasms, most ofwhich have not been previously associated with exposure to chlorophenoxy herbicides. 7 deaths fromtesticular cancer were recorded, with at least a twofold increase in mortality for the combined group of exposed workers (SMR=220 [89-454) and for the production workers (5 deaths, SM R=278 [90-648]). 5 deaths occurred 5 or more years after first exposure, and risk was higher in workers probably exposed to TCDD (SMR=296) compared to those probably not exposed (SMR =164). Thyroid cancer mortality was increased for the combined group of exposed workers (4 deaths, SMR=357 [97-914]), the excess applying both to sprayers and production workers, with deaths registered in three countries. 3 deaths from thyroid cancer occurred 10 or more years after first exposure, and risk was higher for workers probably exposed to TCDD (SM R=426) compared to those probably no exposed (SMR = 308). 3 deaths from neoplasms of other endocrine glands occurred in the UK with increased mortality for the combined group of exposed workers (SMR=454 [941328]), and separately in sprayers and production workers. Increased mortality from neoplasms ofnose and nasal cavity (3 deaths, SMR = 283 [58-827]) was similarly observed only in the UK, with the highest risk in sprayers. The mortality ofcases exposed through accidents was not increased either for all causes (33 deaths, SMR = 98 [67-137]) or for all neoplasms (13 deaths, SMR =120 [64-205]). Similarly, no increased risk was seen for chloracne cases for all cause mortality (13deaths, SMR = 66 [35-113]) or for al neoplasms (5 deaths, SMR=98 [32-228]). No deaths from soft-tissue sarcoma or nonHodgkin's lymphoma were observed in these groups, but the expected numbers were very low. Results were virtually unchanged when analyses were repeated with exclusion ofall workers with less than one year exposure. Analyses by time since first exposure and duration ofexposure forworkers probably exposed to T CDD did not show any trends. Analysis using Poisson regression for all cause mortality, all neoplasms, soft-tissue sarcoma, and non-Hodgkin's lymphoma, did not reveal different pattern of risk than that shown in die SMR analysis. Discussion The IARC register provides an opportunity to study, with a common protocol, the mortality experience of workers producing and spraying chlorophenoxy herbicides and/or chlorinated phenols in ten countries. This cohort study is the largest to have been done on these categories of workers. Nonetheless the attempt to associate risks with specific agents was only partly successful because there was often simultaneous exposure to several different chlorophenoxy herbicides or chlorophenols (table I) and to other pesticides, raw materials, intermediates, and processing chemicals. The risk specifically related to chlorophenoxy herbicides is best evaluated by looking at sprayers, who are exposed mainly to these compounds and, in smaller amounts, to other herbicides, and only to negligible amounts of chlorophenol impurities. Workers producing chlorophenoxy herbicides may also have been exposed to chlorophenols during the production process. It was not possible to identifya largegroup ofworkers exposed solely to chlorophenols. The most toxic dioxin (TCDD) can be formed during production of 2,4,5-T or 2,4,5-TCP so the identificationoffactories which did not produce 2,4,5-T or produced only very small amounts and of sprayers not using 2,4,5-T allowed a population to be distinguished in which exposure to TCDD was unlikely (with the caveat that' even occasional exposures to high concentrations ofTCDD may lead to accumulation of high tissue burdens1*). A non-significant increased risk was observed for soft tissue sarcoma, the excess being significant for sprayers in an analysis by time since first exposure. All 4 cases (in four countries) occurred 10-19 years after first exposure, a time shorter than that observed in Sweden10or the USA.14The increased risk was not confined to workers probablyexposed 1052 THE I.ANCl-T VOL TW: OOT 26, |W | 10 IC .n O . ( It the 5 iktdiuonal registered cases of sui t-tissue sarcoma, iilenlilied t'rom oilier morbidity or mortality records; 3 production workers, 1 sprayer, l noil-exposed) 1 was in a w orker probably exposed to T C O O . 11 Green UM. A cohort nmriuliiv >iu<J\ ol lorotrv workers exj'oscd io phenoxv acid herbicides B r 7 h id M %d |uo|, 48: 23-U9s It* Hardcll l.. Sandsirom A taw-control Muds Soft-tissue sarcoma and exposure to phenoxy acelie .iuds or chlorophenols. B i 7 C u m \r 1070, 39:711-17. A sm all, non-significant increase in mortality from 11 Ilardell l ., Unksson M, l.enner 1*. I.ungren U. Malignant lymphoma.ind non-Hodgkin's lymphoma was observed among production workers, most deaths occurring more than 10 years after first exposure. 6 out o f the 11 deaths were in workers exposed for exposure to chemicals, especially organic solvents, chlorophenols and phenoxv acids; a cisc^onirol Mud\ . B r J C a n te r 1981.4.3: h>9-76. 12. Daldcrup LM. Zellenruth IVDioxinexposure. 20vear tollow-up l.a iu e t l83;u: 1134-35. less than one year. O ther .srudies'^'have, how ever, shown 13. Coggon D, Punnet! B, Winter P Mortalityand incidenceol cancerat lour nsks associated with exposure to chlorophenoxy herbicides higher for non -H od gkin's lym phom as than tor soft-tissue sarcomas. T here was no increase in mortality from factories making phenoxv herbicides. H r J h id A ted J99|; 48: 173-78. 14. Hoar SK, Blair A. Holmes FF, Boynscn GP, Kobel KJ, Hoover K. Fraumem JJ Jr. Agricultural herbicide use and nsk of lymphoma and soft tissue sarcoma. " J A M A 1986,256: 1141--47 H odgkin's disease, and the evidence for an association o f 15 Hoar /.ham S. Weisenburger Pl>. Babbitt PA. Saal RG. Vaughi JB. with exposure to chlorophenoxy herbicides has been weaker than that for non-H ixlgkin's lymphoma. W e found increased risks for some-uncommon neoplasm s Gantor KP, Blair A. Acase-control stuJvoi non-1lodgkin's lymphoma and the herbicide 2,4-dichlort*phenoxyaceuc acid 2.4-Di in liastcm Nebraska. Iipidennoli> ay 1990. 1: 349~5n 16. Fingerhut MA, Halperin WE. Marlow DA. et at. Ganccr mortality in but these results are difficult to interpret because o f the small numbers. Neoplasm s of the thyroid and other endocrine glands have not been previously linked with chlorophenoxy herbicides in man but exposure to T C D D and chlorophenols have been associated with neoplasms o f the workersexposed to2.3.7.8-teir;ichlor\<diben/.o-p-dioxtn. .Vfin a l J M e d 1991;.324: 212-18. 17. Lilienfeld DE, Gallo MA. 2.4-P. 2.4.5-1' and 2.3.7.8-TCDD an overview-, E p id e m io l K tT 1989; IL 28-58. 18. (Centers for Disease (Control Preliminary report: 2.3.7.8tetrachlomdibcnzo-p-dioxin. exposure to humans--Seveso. Italv thyroid and the adrenals in m ice and rats." Af.UlVK 1988; 48:73V3h Interpretation o f our findings will be easier when follow -up o f this large cohort is longer-- ie, when the number o f recorded deaths is greater. T h e pattern so far 19 Pearce NE, Smith AH, Howard JK, Sheppard RA. Cilles HJ, Teague GA. Non-Hodgkins lymphoma anjexposure to phenoxv herbicides, chlorophenols, fencing work, and meat works employment: a case- contn.il study. H r J h u t M e d 1986; 4.3: 75-83 indicates no increased mortality for neoplasm s in general for 2U. Persson B, Dahlander A, Frcdriksson M, Hrage HN. Ohlstm G.-Ci, the most com m on epithelial cancers, and no clearly detectable excess for non -H od gkin's or for H odgk in's lymphoma. T h e significant six-fold excess o f soft-tissue Axelson O. Malignant lymphomas and occupational exposures. B r J h u i M e d 1989; 46: 516-20 21. Smith .AH. Pearce N, Fisher LX), Giles HJ. Teague CA, Howard JK. Soft tissue sarcoma and exposure to phenoxv herbicides and sarcomas occurring in the period 10-19 years stnee first chlorophenols in New Zealand. J S a t t C a n c e r In st 1984; 72: 1111-17. exposure in the w hole cohort, rising to a nine-fold excess in 22. Vincis P. Tvrracini B, Ciccone G. Cignetn A, Colombo H, iTunna A, sprayers, is com patible with a causal role for chlorophenoxy herbicides, though not specifically for those probably contaminated with T C D D . Math L, Pisa R, Ricci P, Zamni E, ( a*mha P. Phenoxv herbicides and stft tissue sarcomas m female rice wevJorv a population-based case-control study. S c a n d J U' ,ir/i E m m m H e a lth 1987; 13: 9-17. 2). WiglePT, ScmcnciwRM, WilkinsK. RiedelD.Rmer [., Morrison HI. Mao Y. Mortality study of Canadian male farm operators: non- Supported by grant No l-ES-95276 of the US National Institute of F.mironmetual Health Sciences. We thank line Johnson for hiscontribution msetting-up theregisterand David Hod forsupport throughout theproject; Hciko Boeher, Marilyn Fingerhut. and Paolo BofTetu for constructive comments on an earlier draft; David Marlowand William Parsons for help Hodgkin's lymphoma mortality and agricultural practices in Saskatchewan. J N a t l C a n cer In st 19Qt); 82: 575--82. 24 Wiklund K, Dich J, Holm U-E, Eklund G. Risk of cancer in pesticide applicators in Swedish agnculrure. B r J h id Aled 1989; 46: 809-14. 25. Woods JS, Polissar L, Scvcnson RK, Henser LS, Kulander BG. Soft with planningthe industrial hygiene investigation; Gilles Ferro forassistance m data management, and Agnes Hanss-Cousseau for manuscript preparation. K.A. L A was in receipt of a research fellowship from IARC tissue sarcoma and non-Hodgkin's lymphoma in relation to phenoxv herbicide and chlorinated phenol exposure in western Washington. 7 S a i t C a n c e r h ist 1987; 78: 809-9UV during part of the work on this study 26. Zober A, Messerer P, Huber P Thiriy-four-year mortality follow-up of BASF employees exposed to 2,3,7.8-TCDD alter the 1953 accident. REFERENCES I n i A r c h O c c n p E n v ir o n H e a lth 1990, 62: 139-57. 27. IARCMonographs on the Evaluation ofCarcinogenic Risks to Humans. 1 International Agency for Research on Cancer Some halogenatcd hvdn*carbons and pesticide exposures. In: Monographs on the cvaluatH>n of the carcinogenic risk of chemicals to humans; vol XLl. l.yon IARC. 1386; 346. 395 2 Bcna/zi PA. Zocchctti C. Pcsaton AC, Guerctlena S, Sananco M. Ten-year mortality study of the population involved in the Scvcso Overall evaluations of carcinogenicity an updating of I A R C M m u tg r 1--42'suppl 7?. Lynn; IARC, 1987. 28. IARC Working Group. Phenoxv acid herbicides and contaminants description of the IARC International Register of Workers A m y h id M e d 1990; 18: 39-45. 29 Coleman MP, Hermon C, Douglas A Person-years -PYRS): a Fortran incident in 1376 A m J E p id em io l 1989; 129: 1187-21X). 3. BnndGG, WetterstrocmNH. RoushGj.Mcl.aren FA, LippsTE,Cook program for cohort study analysis WHO IARC internal report no 89 006'. Lyon: IARC, 1989 RR. Cause specific mortality among employees engaged in the 30 C'heckoway H, Pearce NE, Crawford-Brown DJ. Research methods in manufacture, formuiation or packaging of 2,4-dichlon`phenoxyacettc occupational epidemiology NewYork; Oxford University Press. 1989 acid and related salts. B r ] I n J M e d 1988. 45: 98-105. 31. World Health Organisation. Manual of the international statistical y $ 4 Coggon D, Panned B. Winter PD, Acheson ED, Bonsall J. Mortality of workers exposed to 2 methyl-4 chlorophenoxyacctic add. S c u n J J !V'"<*rk H e a lth 1986; 12: 448-54. classification-of diseases, iniunes and causes of death 7th revision conference). Geneva: WHO, 1957. 32 World Health Organisation. Manual of the international statistical 5 Cook RR.Bond GG, Olson RA.Ou MG.Gondck MR Evaluationofthe classification of diseases, iniuries and causes of death f8th revision mortality experience of workers exposed to chlorinated dioxins. conference;. Geneva: WHO, 1967. C h cm o tp h ere 1986; 15: 1969-76 6 Eriksson M. Hardcll l.. Berg NO. Moller T, .Axelson O Soft tissue 33 W'orld Health Organisation. Manual of the international statistical classification of diseases, injuries and causes of death 9th revision sarcomaand exposure tochemical substances acase-referent study. B r J h id M e d 1981.38: 27-33 conference:. Geneva: WHO, 1978 34. Fingerhut MA, Halpenn W*E, Honchar PA, Smith AB. Groth DH, 7 Eriksson M. Hardcll L. Adami HO Exposure todioxins as a nsk factor Russell W'O Anevaluationofreports ofdioxin exposureandsoit tissue for soli tissue sarcoma, a population-based case-control study. J N a il f.utiivr hi>t 1990, 82: 486-90. sarcoma pathology among chemical workers in the United Stales. S t a n d J U" irJfcE n v iro n H e a lth 19H4; 10: 299--31.33 8. l.yngc E. A follow-up study ol cancer incidence among workers m manufacture ofphenoxv herbicides in Denmark. B r J C ancer 1985; 52: 259-70. 35. HulT JE. Salmon AG, Hixiper NF. Zeise !.. laing-term ca-cwogenesis studies on 2,3,7,8-tetrachlorudibcnzo-p-dioxin and hexachlorodiben/o-/i-dioxin. C e ll B io l T o xteo l 1991; 7: 67-94. 3995 o -iti1 / 2_ / 7_ 3996 Q -H 093- la; und i\ 1?u'iKk'd `!;c i.'iiaiKy. . ' the co u rtro o m , ho beat the bcM Ow I'.'-.' ' i c licek. Iletu.ii I G .'uliia.-. "1 leatned a I: v('in their m>. : o Obituaries I Iif im -- iis in mu v i w n a M w a o M m a u r i M R r m m n m M m i n a n M x i n 'i n I . admiral's son dies of Agent Orange ills United P rm International FAYETTEVILLE, N.C. -- Elmo Zumwtlt III, who in a tragic irony was exposed to Agent Orange ordered ` dropped on the Vietnam jungles by his father, died Saturday of cancer, a family spokeswoman said. He was 42. His father, Adm. Elmo Zumwalt Jrn and his brother, Jim Zumwalt, were at his side when he died at his home in Fayetteville at 6:30 a.m., the spokeswoman said. Elmo Zumwalt ill had suffered from Hodgkin's disease and lvmphoma. cancers linked to the toxic substance Agent Orange. The spokeswoman said a service for Mr. Zumwalt, an attorney, will be held Wednesday in Fayetteville. A White House spokesman said, "The president and Mrs. Reagan are deeply saddened and extend their prayers to the Zumwalt family." When Zumwall's father, tlu* Amer ican naval commander in Vietnam, ordered the use of Agent Orange to defoliate the guerrilla-infested jungles in the Southeast Asian nation, the toxic substance was thought harmless to humans. Later, it was learned the defoliant causes birth defects and cancers. Mr. Zumwalt and the son he had after the war were both victims of that toxicity. Hut the admiral and his son said they would not rewrite history if given the chance, despite the younger Zumwall's battles with four rounds of cancer and his son's severe attention- deficit disorder. "1 definitely believe my son wot:!.! not ha\c had an additional 20 sea: of life had wc not used it," he Zutnwait said in a telephone mu t .kw Saturday from his son's home, lie contended that "thousands who arc alive today would not be" if the defoliant ha I not been sprayed. "doth my s"ti and 1 belie'c the horrible casualty rates had to be reduced. Thousands of lives were saved," he said, adding that he docs not doubt a link between Agent Orange and tragic health conse-> qucuces. "Doth my son and I made it dear that although the medical evidence is not yet absolutely definitive, we believe there is no doubt that the Agent Orange has caused cancer and birth defects for the population that was exposed," he said. Mr. Zumwalt once said he did not fault his father for ordering the use of the chemical. A lawsuit, brought by many Viet nam veterans suffering the adverse affects of Agent Orange, recently was settled for SISO million without any admission of guilt by the defoliant's manufacturers. The elder Zumwalt said about 250,000 veterans were exposed to the chemical. *1V'-f'fs' ' V 38S7 3 /o r p p \-mo 4 /' / P APPENDIX A PARTI NUMBER / DATE DOCUMENT AUTHOR: ADDRESSEE COPYEE: 1V CARREON DOW 09/12/83 RE DOCUMENT 09/12/83 AUTHOR: ADDRESSEE: COPYEE: CARREON DOW y RE DOCUMENT 07/20/82 AUTHOR: ADDRESSEE: COPYEE CARREON RE RAO KS DOCUMENT 9 09/06/82 AUTHOR: G ANATZ RL ADDRESSEE COPYEE in DOCUMENT 07/20/82 AUTHOR: ADDRESSEE: COPYEE: CARREON RE WATANABE PO DOCUMENT y 12/11/81 AUTHOR: ADDRESSEE: COPYEE: CARREON RE WATANABE PG RAO KS RAMPY TOX FILES TYPE 1P A G E S REPORT JOHNSON KA 19 \/ ABSTRACT JOHNSON KA REPORT JOHNSON KA DOW 32'/ AUTH DOW 1 ABSTRACT JOHNSON KA DOW REPORT Y A N O BL DOW DOW BRANSON 39 ' S TITLE PAGE 1 XRM-A715 HERBICIDE FORMULATION' ACUTE TOXICOLOGICAL PROPERTIES. MALL JM RAO KS XRM-A715 HERBICIDE FORMULATION' ACUTE TOXICOLOGICAL PROPERTIES. AND D REPORT. LAB REPORT CODE HETM-00A715-001. HALL JM KAO KS R EXPERIMENTAL FORMULATION XRM-A660 ACUTE TOXICOLOGICAL PROPERTIES AND INDUSTRIAL HANDLING HAZARDS. HALL JM HATANABE PG REQUEST FOR PRELIMINARY TOXICOLOGICAL STUDIES. EXPERIMENTAL HERBICIDE FORMULATION XRM-4660. EXPERIMENTAL FORMULATION XRM-A660 ACUTE TOXICOLOGICAL PROPERTIES AND INDUSTRIAL HANDLING HAZARDS. R AND D REPORT. LAB REPORT CODE HET M-A660-(l). HALL JM RAO KS TRICHLOPYR PLUS 2,A-D PLUS PICLORAM' ACUTE TOXICOLOGICAL PROPERTIES AND INDUSTRIAL HANDLING HAZARDS. HALL JM RAO KS KEELER PT SCHNEIDER LOCKHOOD DD CRI 4002 NUMBER DOCUMENT 7 DATE 01/19/82 AUTHOR: CARREON RE WATANABE PG ADDRESSEE: COPYEE: RAO KS DAVEY KF LOCKWOOD DD BRANSON TALCOTT AT DOCUMENT 09/30/81 AUTHOR* BARR M DR ADDRESSEE COPYEE: DOCUMENT 9 w 07/21/83 AUTHOR ADDRESSEE: COPYEE: BEAVERS DOW DOW CRI JB DOCUMENT 10 ^ 08/01/83 AUTHOR: ADDRESSEE COPYEE BEAVERS JB ALEXANDER HC DOW CHEN WL HEINIGER GD LICKLIDER KS MARTIN JB PENNINGTON JY SHEETZ DP VERSCHUUREN H DOCUMENT llv 00/00/77 AUTHOR: ADDRESSEE: COPYEE: DIGIOVANNI JUCHAU MR J TYPE ABSTRACT PAGES / 2V Y A N O BL DOW DOW DOSTAL RL LOEFGREN C SCHNEIDER CRI TITLE PAGE 2 TRICHLOPYR PLUS 2,4-D PLUS PICLORAM' ACUTE TOXICOLOGICAL PROPERTIES AND IDUSTRIAL HANDLING HAZARDS. R AND D REPORT. NO. D4-0212-1246-(l) (820659). LAB REPORT C O D E HET DR-0212-1246-(1). WALL JM RAO KS CRI CAPUTO R GEHRING PJ OBREGON E RINZEMA LC TOX FILES CHEN HL KEELER PT RAMPY STEWARD D LANGNER RR REPORT 44 NEUROLOGICAL EFFECTS OF HERBICIDES AND PESTICIDES. AN EXPLANATION TO A CURRENT TOXICOLOGICAL CRISIS, AND A POSSIBLE SOLUTION TO P R E V E N T F U R T H E R TRAGEDY. ( I N C L U D E S NE W S A R T I C L E S VOL 2, CHAP 20, CEREBRAL INTOXICATION (PAGE 11) AND CLINICAL NEUROLOGY (PAGE 10). REPORT AVIAN BETSO JE 17 1/ AN ACUTE ORAL TOXICITY STUDY IN THE MALLARD WITH 2,4-D ISOPROPYLAMINE SALT. FINAL REPORT, PROJECT NO 103-226. JABER M WILDLIFE INTL LTD GANTZ RL SCHOBER AE ABSTRACT AVIAN DOW ALLEN BA DAIGRE GW KAGEL RO LOEFGREN C MCDONALD K RAMPY LW SHEWBART KL VEURINK GR 1 V/ AN ACUTE ORAL TOXICITY STUDY IN THE MALLARD WITH 2,4-D ISOPROPYLAMINE SALT. R&D REPORT. CRI NO. 833376. LAB REPORT CODE ES-623. JABER M WILDLIFE INTL LTD ANDERSON JA DEGESERO RA LANGNER RR RINZEMA L MERCER C ROWE R SIM CW WILSON JD BALLANTYNE GD GEHRING PJ LEBEAU JE LUOMA EV MILLIGAN DJ SCHOLLEMANN F STRAWTER BJ ANDERSON WE ABSTRACT 1 VIAJE A UNIV WA SEATTLE TUMOR INITIATING ABILITY OF TCDD AND AROCHLOR 1254 IN THE TWO STAGE SYSTEM OF MOUSE SKIN CARCINOGENESIS (BULLETIN ENVIRON TOX 18(5) 552-557 HPESTICIDES ABSTRACTS 78-2107). BERRY DL SIAGA TJ o k 'd NUMBER DATE DOCUMENT 12 00/00/79 AUTHOR LUSTER ML ADDRESSEE COPYEE DOCUMENT 13v 00/00/79 AUTHOR ADDRESSEE COPYEE ALLEN JR UNIV HI / DOCUMENT 1 4 ^ 00/00/79 AUTHOR ROBBINS A ADDRESSEE COPYEE DOCUMENT AUTHOR ADDRESSEE COPYEE V MAY G 00/00/77 DOCUMENT 1 6 V 00/00/82 AUTHOR ADDRESSEE COPYEE RAMSEY JC GEHRING PJ DOCUMENT 17^ 00/00/80 AUTHOR ADDRESSEE COPYEE KOCIBA RJ DOH / DOCUMENT 18 V 06/00/80 AUTHOR ADDRESSEE COPYEE BRONZETTI G SUZUKI TYPE PAGES ABSTRACT FAITH RE TITLE PAGE 3 LABORATORY STUDIES ON THE IMMUNE EFFECTS OF HALOOENATED AROMATICS (ANN NY ACAD SCI 320, 473-486)(911 6 9 4 3 1 F ) . CLARK G NIEHS ABSTRACT BARSOTTI DA IV REPRODUCTIVE EFFECTS OF HALOOENATED AROMATIC HYDROCARBONS ON N O N H U M A N P R I M A T E S (ANN NY A C A D SCI 320, 4 1 9 - 4 2 5 1 ( 9 1 '1 6 9 4 3 0 E ) . LAMBRECHT LK VANMILLER JP ABSTRACT NIOSH REPORT 3 V DIOXIN STUDIES (SCIENCE 205)(INCLUDES 2 COPIES AND A REQUEST FOR JOURNAL ARTICLES). TCDD IN THE UK. REPORT HEFNER JG DOH 5 THE IN VIVO BIOTRANSFORMATION OF TCDD IN THE RAT (TOX AND APPLIED PHARMACOLOGY 65, 180-184). KARBOHSKI RJ BRAUN HH ABSTRACT KEELER PA 2 V TCDD, RESULTS OF A 13 WEEK ORAL TOXICITY STUDY IN RATS (INCLUDES INSTRUCTIONS FOR PREPARING AN ABSTRACT FOR 1975 MEETING OF THE SOCIETY OF TOXICOLOGY). PARK CN GEHRING PJ ABSTRACT GENETIC EFFECTS OF TCDD IN VITRO AND IN VIVO USING D7 STRAIN OF S CEREVISIAE (MUTATION RESEARCH 74(3)). LEE I ZEIGER E MALLING H LAB DI M UTAGENESI E DIFF NIEHS NUMBER DOCUMENT 19 DATE 00/00/78 TYPE ABSTRACT PAGES 1 AUTHOR* ADDRESSEE* COPYEE* MCCONNELL NIEHS EE MOORE JA DOCUMENT 20 00/00/71 AUTHOR* COLLINS TF ADDRESSEE* COrYEE* ABSTRACT MILLIAMS CH 1 \/ DOCUMENT 21 \ X 00/0 0 / 7 8 ABSTRACT AUTHOR* RASMUSON BO ADDRESSEE* COPYEE* DOCUMENT AUTHOR* ADDRESSEE* COPYEE* 22 LENG ML LENG ML LENG ML SCHOBER 11/18/75 AE SVAHLIN HO LETTER MCCOLLISTER DD C O U L T E R LL THOMAS PA DOCUMENT AUTHOR* ADDRESSEE* COPYEE* 23 v LENG ML GEHRING 06/29/72 PJ MEMO DOM DOM DOCUMENT 24'/ 00/00/81 NEMS 13 ' S AUTHOR* HARDELL H ADDRESSEE* COPYEE* / REPORT UNIV OF UMEA SMEDEN DOCUMENT 25 00/00/81 NEMS REPORT AUTHOR* HARDELL L ERIKSSON M ^ UNIV OF UMEA SWEDEN ADDRESSEE* COPYEE* 1fr- TITLE PAGE 4 THE COMPARATIVE TOXICITY OF CHLORINATED DIIENZO-P-DIOXINS IN MICE AND GUINEA PIGS (TOX AND APPLIED PHARMACOLOGY 44(2), 335-336)(PESTICIDE ABSTRACTS 78-2199). HASEMAN JK HARRIS MH TERATOGENIC STUDIES WITH 245T AND 24D IN THE HAMSTER (BULL ENVIRON CONTAM TOX 6(6), 550-567)(SELECTED REVIEWS FROM THE LITERATURE). FDA MUTAGENICITY TESTS OF 24D AND 245T IN GENETICALLY STABLE AND UNSTABEL STRAINS OF DROSOPHILA MELANOGASTER (ECOL BULL 217, 190-192). UNIV UMEA SWEDEN FAO WHO OPINION ON 24D AND 245T. DAVIDSON JH GEHRING PJ TRANSMITTAL OF ERNE KO PAPERS C T T L . ON THE RELATION OF SOFT TISSUE SARCOMA, MALIGNANT LYMPHOMA AND COLON CANCER TO PHENOXY ACIDS, CHLOROPHENOLS AND OTHER AGENTS (SCANDANAVIAN JOUR OF WORK, ENVIRON 8 HEALTH). MALIGNANT LYMPHOMA AND EXPOSURE TO CHEMICALS, ESPECIALLY ORGANIC SOLVENTS, CHLOROPHENOLS AND PHENOXY ACIDS, A CASE CONTROL STUDY (BRITISH JOUR OF CANCER 43, 169-176). LENNER P LUNDGREN E NUMBER DOCUMENT 26 DATE 00/00/79 AUTHOR HARDELL L ADDRESSEE * COPYEE DOCUMENT 27 ^ 00/00/80 AUTHOR ADDRESSEE COPYEE ERIKSSON H AXELSON 0 DOCUMENT 28 00/00/79 AUTHOR HARDELL L ADDRESSEE COPYEE: DOCUMENT 29 ^ ^ O B00/00/77 AUTHOR: HARDELL L ADDRESSEE COPYEE: DOCUMENT 30 00/00/81 AUTHOR: HARDELL L ADDRESSEE: COPYEE: DOCUMENT 31 03/00/8A AUTHOR ADDRESSEE COPYEE MATTSSON DOW JL ^3 o o cn TYPE PAGES TITLE PAGE NEWS 3^ REPORT UNIV OF UMEA SWEDEN MALIGNANT LYMPHOMA OF HISTIOCYTIC TYPE AND EXPOSURE TO P H E N O X T A C E T I C A C I D S O R C H L O R O P H E N O L S ( L A N C E T 1 55-56). 5 NEWS 12 REPORT HARDELL L UNIV OF UMEA SWEDEN SOFT TISSUE SARCOMAS AND EXPOSURE TO CHEMICAL SUBSTANCES, A CASE REFERENCE STUDY (BRITISH JOUR OF IND HYGIENE). BERG NO HOLLER T UNIV OF LINKPING SHEDEN NEWS A REPORT SANDSTROM A CASE CONTROL STUDY, SOFT TISSUE SARCOMAS AND EXPOSURE TO P H E N O X T A C E T I C A C I D S OR C H L O R O P H E N O L S ( B R I T I S H J O U R OF C A N C E R 39, 711-717). UNIV OF UMEA SHEDEN NEWS A^ REPORT UNIV OF UMEA SWEDEN SOFT TISSUE SARCOMAS AND EXPOSURE TO PHENOXY ACIDS, A CLINICAL OBSERVATION (LAKARTIDNINGEN 7A, 2753-275A). NEWS 33 REPORT UNIV OF UMEA SWEDEN EPIDEMIOLOGICAL STUDIES ON SOFT TISSUE SARCOMA AND MALIGNANT LYMPHOMA AND THEIR RELATION TO PHENOXY ACID OR CHLOROPHENOL EXPOSURE (UMEA UNIV MEDICAL DISSERTATIONS 65). UNIV OF LINKPING SHEDEN PRESENT REPORT ALBEE RR 39 NEUROTOXICOLOGIC EXAMINATION OF RATS DERMALLY EXPOSED TO 24D AMINE FOR THREE WEEKS (50C OF TOX, ATLANTA GA). JOHNSON KA QUAST JF NUMBER -DATE DOCUMENT 32 ) / 00/00/85 AUTHOR MATTSSON JL ADDRESSEE COPYEE DOCUMENT 33 00/ 00/86 AUTHOR MATTSSON JL ADDRESSEE COPYEE DOCUMENT 34 00/00/77 AUTHOR CROFT H ADDRESSEE COPYEE DOCUMENT AUTHOR ADDRESSEE COPYEE 35 ^ 12/07/67 B E N D E R SL DOW KRAMER CG BAILEY CZ DOCUMENT 36 \ / 0!1/06/86 AUTHOR DILL DC ADDRESSEE COPYEE DOCUMENT 37 ^ 01/09/86 AUTHOR ADDRESSEE COPYEE CIESZLAK FS KROPSCOTT BE DOCUMENT 03/00/86 AUTHOR ADDRESSEE COPYEE LANDRY TD W O L F E EL TYPE REPORT Dl PAGES \ \ fP ^ TITLE PAGE THE IMPROBABLE ASSOCIATION BETWEEN THE HERBICIDE 24D AND POLYNEUROPATHY. 6 NEWS REPORT JOHNSON KA 7 LACK OF NEUROPATHOLOGIC CONSEQUENCES OF REPEATED DERMAL EXPOSURE TO 24D IN RATS (FUNDAMENTAL S APPLIED TOX 6 175-181). ALBEE RR DOW YANG KH 3 PATHOLOGICAL EFFECTS OF TCDD ON THE COMMON BILE DUCT OF RATS (FED PROC 36(3)XINCLUDES PHOTOCOPY REQUEST FOR JOURNAL ARTICLES). PETERSON RE UNIV HI MINUTES DOW STAEHLINO EC HOYLE HR WIDIGER AH MILAZZA DP 15 DOWICIDE PLANT ENVIRONMENTAL CONTROL TASK FORCE. HOLDER BB SAUERS RC MUTCHLER JE ROWE VK CLARK GA EVALUATION OF THE TOXICITY OF TECHNICAL PICLORAM TO FRESHWATER GREEN ALGA ES-824. TAKAHASHI IT DOW LANDRY TE DOW 185 PICLORAM A TWO UEAR DIETARY CHRONIC TOXICITY - ONCOGENICITY STUDY IN FISCHER 344 RATS HET K-38323-(34). WOLFE EL JOHNSON KA QUAST JF 2./ v GORZINSKI SJ DOW PICLORAM; A TWO YEAR CHRONIC TOXICITY AND ONCOGENICITY STUDY IN FISCHER 344 RATS (THE TOXICOLOGIST, ABSTRACTS OF THE 25TH ANNIVERSARY MEETING 6(1)) (331). CIESZLAK FS KROPSCOTT BE X O lh -( O o 03 NUMBER tATE DOCUMENT 39 00/00/85 AUTHOR: JOHNGREENE JA JOHNSON KA ADDRESSEE COPYEE y DOCUMENT 40 00/00/00 AUTHOR MULLISON HR ADDRESSEE COPYEE: DOCUMENT 41V' 04/09/85 AUTHOR! GOLLAPUDI BB JERSEY GC ADDRESSEE COPYEE: DOCUMENT 42 V 06/12/84 AUTHOR HOPKINS DL ADDRESSEE: COPYEE! / DOCUMENT 43 V 06/18/84 AUTHOR GERSICH FM TAKAHASHI IT ADDRESSEE: COPYEE: DOCUMENT 44 AUTHOR MAYES HA TAKAHASHI IT ADDRESSEE COPYEE: DOCUMENT 45 AUTHOR FOX TR DOH ADDRESSEE! COPYEE: 08/16/84 \O Ok o Ui TYPE PAGES 4 OUELLETTE JH RAO KS DOW 26 y / ' ' MCCLINTOCK ML 18/ X TAKAHASHI IT 18 1 / HOPKINS DL DILL DC 24 V REITZ RH SCHUMANN AM TITLE PAGE 7 TERATOLOGICAL EVALUATION OF PICLORAM POTASSIUM SALT IN RABBITS (FD CHEM TOXIC 00(0), 000-000). OULLETTE JH J E F F R I E S TIC DON A TOXICOLOGICAL AND ENVIRONMENTAL REVIEH OF PICLORAM EVALUATION OF PICLORAM IN THE MOUSE BONE MARRON MICRONUCLEUS TEST TXT sK - 038323-039. NILKERSON JE DON THE DETERMINATION OF A-AMINO-3,5,i-TRICHL0R0PIC0LINIC ACID IN HATER BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY DURING AQUATIC TOXICITY STUDIES ES-681. DON THE ACUTE AND CHRONIC TOXICITY OF TECHNICAL PICLORAM (4-AMINO-3,5,6-TRICHLOROPICOLINIC ACID) TO DAPHNIA MAGNA STRAUS ES-690. MILAZZO DP DON THE TOXICITY OF TECHNICAL PICLORAM TO THE EMBRYO, LARVAL, AND JUVENILE STAGES OF THE RAINBOH TROUT (SALMO GAIRDNERI RICHARDSON) ES-703. HOPKINS DL DON BIOLOGICAL MECHANISMS INVOLVED IN THE TOXICITY OF PICLORAM HERBICIDE IN RATS HET K-038323-037. MENDRALA AL JOHNSON KA NUMBER /DATE DOCUMENT 46 V ' 00/00/84 AUTHOR NOLAN RJ DOW ADDRESSEE COPYEE: TYPE PAGES 6 FRESHOUR NL TITLE PAGE 8 PHARMACOKINETICS OF PICLORAM IN MALE VOLUNTEERS (TOX AND APPLIED PHARMACOLOGY 76,264-269). KASTL PE SAUNDERS JH DOCUMENT 47 02/00/84 AUTHOR I PUBLIC HEALTH SERVICE ADDRESSEE COPYEE 14 TOXICOLOGY RESEARCH AND TESTING OVERVIEH. NATIONAL T0CIC0L0GY PROGRAM ANNUAL PLAN FOR FISCAL YEAR 1984 NTP-84-023. DEPT HEALTH HUMAN SERVIC DOCUMENT 03/12/73 AUTHOR SUSCHETET M ADDRESSEE COPYEE CAUSERET J TOXICOLOGY AND NUTRITION (TOXICOLOGIE ET NUTRITION) (C R ACAD SC PARIS 276 SERIES D, 1775-1777M0RINGINAL ARTICLE AND TRANSLATION) TRUHAUT R DOCUMENT 49 '/ 01/00/84 AUTHOR LIBICH S ONTARIO HYDRO ADDRESSEE COPYEE 7 OCCUPATIONAL EXPOSURE OF HERBICIDE APPLICATORS TO HERBICIDES U SED ALONG ELECTRIC POWER TRANSMISSION LINE RIGHT OF WAY (AM IN D HYG ASSOC JOUR 45(1), 56-62). TO JC FRANK R SIRONS GJ ONTARIO MINISTRY AG AND DOCUMENT 50 10/10/83 AUTHOR BEAVERS JB WILDLIFE INTL LTD ADDRESSEE COPYEE . JABER M 17 V AN ACUTE ORAL TOXICITY STUDY IN THE MALLARD WITH PICLORAM TECHNICAL WILDLIFE INTERNATIONAL LTD,SOLITUDE CREEK FARM,ST MICHAELS MD 21663 PROJECT NO 103-221 ES-642. ALEXANDER HC DOW DOCUMENT 51 v 08/19/83 AUTHOR: NOLAN RJ DOW ADDRESSEE: COPYEE: 12 FRESHOUR NL RAMSEY JC PICLORAM PHARMACOKINETICS IN HUMAN VOLUNTEERS HEB-DR-0114-1351-1. KASTL PE SAUNDERS JH DOCUMENT 5 2 v 07/28/83 AUTHOR FRESHOUR NL ADDRESSEE COPYEE: HERMANN EA PICLORAM QUANTITATIVE DETERMINATION IN HUMAN BLOOD AND URINE HET-K-038323-036. WAECH1ER JM JR DOW \O O O 00 NUMBER DATE DOCUMENT 53 04/00/83 AUTHOR: BETSO JE ADDRESSEE-- COPYEE! / DOCUMENT 54 v 00/00/83 AUTHOR! BORZELLECA JF ADDRESSEE' COPYEE: > DOCUMENT 55 07/29/82 AUTHOR' GORZINSKI SJ DOW ADDRESSEE: COPYEE: 4 DOCUMENT 56 06/09/82 AUTHOR: BARNALLOYD T MCDERMOTT MC JERSEY GC ADDRESSEE' COPYEE: DOCUMENT 04/30/82 AUTHOR: GORZINSKI SJ DITTENBER DA MCKENNA MJ ADDRESSEE: COPYEE: DOCUMENT 58 ^ 11/16/82 AUTHOR: MAYES MA ADDRESSEE' COPYEE: TYPE DON PAGES 29v TITLE PAGE TOXICOLOGY OF PICLORAM (INCLUDES APPROVAL FOR RELEASE OF PROPRIETARY INFORMATION OUTSIDE OF THE DOH CHEMICAL COMPANY), 9 20 A REVIEW OF VOLATILE ORGANIC CONTAMINANT DATA (PROC. AWWA HATER QUAL TECHNOL CONF 1983, 225-244). VA COMMONWEALTH UNIV JOHNSON KA MCKENNA MJ 98 \ / PICLORAM THE INFLUENCE OF HEXACHLOROBENZENE CONCENTRATION ON PICLORAM INDUCED LIVER TOXICITY IN FISCHER 344 RATS HET K-038323-(33). KROPSCOTT BE PARK CN 141 / TAYLOR HW DUKE RL RESULTS OF A SIX MONTH DIETARY TOXICITY STUDY OF PICLORAM (4-AMINO-3,5,6-TRICHLOROPICOLINIC ACID) ADMINISTERED IN THE DIET TO MALE AND FEMALE BEAGLE DOGS. SWAIM LD HINZE CA GRANDJEAN M DOH JOHNSON KA CAMPBELL RA DOW 39 PICLORAM; RESULTS OF A 2 WEEK DIETARY PROBE STUDY IN CDF FISCHER 344 RATS K-38323-<26). WADE CE HILLIAMS DM HERMAN JR CHEN WL DILL DC THE TOXICITY OF PICLORAM C4-AMINO-3,5,6-TRICHLOROPICOLINIC ACID) TO REPRESENTATIVE FRESHWATER ORGANISMS ES-561. DOW TAKAHASHI IT i o o co NUMBER / DATE DOCUMENT 5 9 0 0 / 0 0 / 7 6 AUTHOR GUERZONI ME ADDRESSEE COPYEE DOCUMENT 60 07/00/78 AUTHOR ROBENS JF ADDRESSEE COPYEE DOCUMENT 00/00/83 AUTHOR WOODRUFF RC ADDRESSEE COPYEE DOCUMENT 62 V 00/00/72 AUTHOR NAIK MN CSIRO AUSTRALIA ADDRESSEE COPYEE: DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 63 00/00/00 DOCUMENT AUTHOR: ADDRESSEE COPYEE: 64 00/00/00 DOCUMENT 00/00/00 AUTHOR' ILLEGIBLE ADDRESSEE: COPYEE: TYPE PAGES / TITLE PAGE 10 M 'S DELCUPOLO L MUTAGENIC ACTIVITY OF PESTICIDES. ATTIVIT MUTAGENICA DEGLI ANTIPARASSITARI (RIV SCI TECN ALIM NUTR UMHORIOINAL ARTICLE AND TRANSLATION). PONTI I BOLOGNA UNIV TRACOR JITCO INC TESTS FOR POSSIBLE CARCONOGENICITY OF 20 PESTICIDES IN OSBORNE MENDEL RATS AND B6C3F1 MICE (ABSTRACTS SEVENTEENTH ANNUAL MEETING 40HTOX AND APPLIED PHARMACOLOGY 45(1), 236). 11 PHILLIPS JP PESTICIDE INDUCED COMPLETE AND PARTIAL CHROMOSOME LOSS IN SCREENS WITH REPAIR DEFECTIVE FEMALES OF DROSOPHILA MELANOGASTER (ENVIRON MUTAGENESIS 5, 835-846). IRWIN D BOWLING GREEN STATE UNIV JACKSON RB MICROBIAL DEGRADATION AND PHYTOTOXICITY OF PICLORAM AND OTHER SUBSTITUTED PYRIDINES (SOIL BIOL BIOCHEM 4(3), 313-323) (TOX AND PHARMOCOLOGY 72-2668). STOKES J SWABY RJ 10v DRINKING WATER AND HEALTH TOXICITY OF SELECTED CONTAMINANTS. 5 V FATE OF BANVEL T, IOXYNIL, TORDON AND TRIFLUORILIN IN THE DAIRY COW ILLEGIBLE DOCUMENT (TITLE CONTAINS RESIDUES AND TRICHLOROPICOLINIC ACID). 1 O * O S' O NUMBER DOCUMENT 66^ DATE 01/00/84 AUTHOR: ADDRESSEE COPYEE: LIBICH S ONTARIO HYDRO DOCUMENT AUTHOR ADDRESSEE COPYEE: 67 V 00/00/72 HUNTER JH DOCUMENT 68 V 00/00/71 AUTHOR) BELOV ADDRESSEE COPYEE DOCUMENT 69 v 00/00/71 AUTHOR: ILLEGIBLE ADDRESSEE COPYEE: DOCUMENT 70 AUTHOR TU CM ADDRESSEE COPYEE: 00/00/69 DOCUMENT 71 12/00/84 AUTHOR LAVY TL ADDRESSEE: COPYEE: DOCUMENT 00/ 00/00 AUTHOR: CONDIE LH ADDRESSEE COPYEE: TYPE PAGES TITLE PAGE 11 OCCUPATIONAL EXPOSURE OF HERBICIDE APPLICATORS TO HERBICIDES USED ALONG ELECTRIC POWER TRANSMISSION LINE RIGHT OF HAY (AM 1ND HYG ASSOC J 45(1),56-62). TO JC FRANK R SIRONS GJ ONTARIO MINISTRY OF AG A STOBBE LH MOVEMENT AND PERSISTENCE OF PICLORAM IN SOIL (HEED SCI 2,186-189), CANADA DEPT AG 1v ON THE TOXICOLOGICAL AND HYGIENIC EVALUATION OF THE HERBICIDE 4-AMIN0-3,5,6-TRICHL0R0PIC0LINIC ACID (TORDON 22K, PICLORAM) (HYG. SANIT. 36(3), 466-469)(73-0137). SATATOV RES INST OF RURA 1V DISSIPATION OF DICAMBA, PICLORAM AND 2,3,6 TBA ACROSS NEBRASKA (PLANT GROWTH REGULATORS 75H97486). BOLLEN HB / 1v/ EFFECT OF TORDON HERBICIDES ON MICROBIAL ACTIVITIES IN THREE WILLAMETTE VALLEY SOILS(DOWN EARTH 25(2), 15-17M70 - 1 3 9 4 ) . CANADA DEPT OF AG MATTICE JD \s / EXPOSURE OF FOREST WORKERS USING HERBICIDES MEASURED (ARKANSAS FARM BUREAU NOV. - DEC. 1984, 8). NORRIS LA HAYES JR ACUTE, 14 DAY AND SUBCHRONIC TOXICITY OF POTASSIUM PICLORAM (PIC) ADMINISTERED TO RATS VIA THE DRINKING WATER (887). BORZELLECA JF MEDICAL COLLEGE OF VA O O A h * NUMBER DATE DOCUMENT 73 -y- 05 / 0 0 / 8 1 AUTHOR: ADDRESSEE COPYEE: DOCUMENT REUBER MD y74 03/20/81 AUTHOR: ADDRESSEE' COPYEE: HOOD DD DOCUMENT 75' 03/20/81 TYPE PAGES 18 V AUTHOR: LOCKHOOD DD ADDRESSEE: COPYEE: DOCUMENT 76 v / 03/20/81 AUTHOR: LOCKHOOD DD ADDRESSEE: COPYEE: DOCUMENT 1 1 ^ / 10/22/80 AUTHOR: ADDRESSEE: COPYEE: CAMPBELL RA / y DOCUMENT 78 V 07/30/80 AUTHOR: ADDRESSEE: COPYEE: TOLLETT SCHUETZ HERMANN JT DJ EA y \ O o h-4 fO JOHNSTON RV BORREGO V 2>y 16 ' HERMANN EA A 60 / BUREK JD D I TTENBER DA GORZINSKI SJ TITLE PAGE 12 CARCINOGENICITY OF PICLORAN (JOUR OF TOX AND ENVIRON HEALTH 7(2), 207-222). ACUTE TOXICOLOGICAL PROPERTIES AND INDUSTRIAL HANDLING HAZARDS OF TORDON ACID; A AND 6 ISOMERS HITH IMPURITIES, HASHED TXT:K-38323-(29). TORDON PLANTS CF-2 MOTHER LIQUOR SOLIDS HITH RESIDUAL SULFURIC ACID, NOT HASHED. DATA SHEET OF PROPERTIES, HEALTH HAZARDS AN D PRECAUTIONS FOR SAFE HANDLING OF MATERIALS (INCLUDES DATA SH EETS ON ACUTE ORAL TOXICITY, EYE IRRITATION TEST, AND PRIMARY SKIN IRRITATION). DOH DANIEL RL ACUTE TOXICOLOGICAL PROPERTIES AND INDUSTRIAL HANDLING HAZARDS OF T O R D O N ACID; < A N D 6 I S O M E R S H I T H I M P U R I T I E S , NOT H A S H E D , T X T : K - 3 3 2 3 - ( 31). DOH JOHNSTON RV DETERMINATION OF A-AMINO-3,5,6-TRICHLOROPICOLINIC ACID, PICLORAM, IN LABORATORY RAT CHOH BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY HET K-038323-(23). DOH BRAUN HH PICLORAM; RESULTS OF A 13 HEEK TOXICITY STUDY IN B6C3F1 MICE HET K-038323-(lA) SUPPLEMENT. HADE CE MORDEN DC SCHNETZ BA KALNINS RV DOH NUMBER DATE DOCUMENT 79 -j- 00/00/74 TYPE PAGES 24 / - AUTHOR ADDRESSEE COPYEE SUSCHETET M SUNLONE INC DOCUMENT 00/00/74 AUTHOR SOMERS J ADDRESSEE COPYEE DOCUMENT 00/ 00/00 AUTHOR COPE FG ADDRESSEE COPYEE DOCUMENT 82 v 00/00/78 AUTHOR SOMER JD ADDRESSEE COPYEE DOCUMENT 83 >/ 00/00/78 AUTHOR ADDRESSEE COPYEE SOMERS JD / DOCUMENT 84 \ I 00/00/75 AUTHOR SOMERS JD ADDRESSEE COPYEE 'O \ O *h o >0 CO LECLERC J / 4 MORAN ET JR 4 DEPT RECREATION CONS\ MORAN ET 1 1 MORAN ET JR 1 TITLE PAGE 13 TOXICITY AND NUTRITIONAL EFFECTS OF TWO HERBICIDES IN THE RAT PICLORAM (4-AMINO-3,5,6-TRICHLORO-PICOLINIC ACID) AND ATRAZINE (2-CHLORO-4-ETHYLAMINO-8-ISOPROPYLAMINO-S-TRIAZINE) (ANNALES DE LA NUTRITION ET DE L'ALIMENTATION 28, 2 9 - 4 7 ) (TRANSLATION BY SUNLONE INC OCTOBER 1975). LHUISSIER M LOISEL H EFFECT OF EXTERNAL APPLICATION OF PESTICIDES TO THE FERTILE EGO ON H A T C H I N G S U C C E S S A N D E A R L Y C H I C K P E R F O R M A N C E 2. C O M M E R C I A L HERBICIDE MIXTURES OF 24D WITH PICLORAM OR 245T USING THE PHEASANT ( B U L L E T I N E N V I R O N C O N T A M I N A T I O N ft T O X 11(1), 339-342). REINHART BS UNIV GUELPH ONTARIO TOXICITY OF TORDON 101 TO RAINBOH TROUT (PESTICIDE PROG 3(4), 89-90)(INCLUDES PHOTOCOPY REQUEST FOR JOURNAL ARTICLES). / BR REPRODUCTIVE SUCCESS OF HENS AND COCKERELS ORIGINATING FROM EGGS SPRAYED WITH 24D, 245T, AND PICLORAM FOLLOHED BY EARLY PERFORMANCE OF THEIR PORGENCY AFTER A COMPARABLE IN OVO EXPOSURE (BULL ENVIRON CONTAM TOXICOL 20(1), 111-119). REINHART BS UNIV GUELPH ONTARIO HATCHING SUCCESS AND EARLY PERFORMANCE OF CHICKS FROM EGGS SPR AYED WITH 24D, 245T, AND PICLORAM AT VARIOUS STAGES OF EMBRYON IC DEVELOPMENT (BULL ENVIRON CONTAM TOXICOL 20(3), 289-293). REINHART BS UNIV GUELPH ONTARIO INFLUENCE OF EXTERNAL APPLICATION OF HERBICIDES ON AVIAN EMBRYOGENESIS AND REPRODUCTION EFFECT OF EGG ENCOUNTER TIME (DISS ABSTR INT B 37,1163B). NUMBER DOCUMENT 85 DATE 00/00/74 AUTHOR) SOMER JD ADDRESSEE) COPYEEi DOCUMENT 86 ^ 00/00/74 AUTHOR) SOMERS J ADDRESSEE COPYEE) DOCUMENT 87 / 00/00/74 AUTHOR) SOMERS J ADDRESSEE COPYEE: DOCUMENT 88 00/00/73 AUTHOR SOMER JD ADDRESSEE) COPYEE DOCUMENT 00/00/72 AUTHOR BREAZEALE FM ADDRESSEE COPYEE) DOCUMENT 90 V 00/00/73 AUTHOR YODER J ADDRESSEE) COPYEE* TYPE PAGES 1 MORAN ET JR 1v' MORAN ET JR iv/ MORAN ET JR MORAN ET JR CAMPER ND 1V MATSON M 1 TITLE PAGE 14 EFFECT OF EXTERNAL APPLICATION OF PESTICIDES TO THE FERTILE EGG ON H A T C H I N G S U C C E S S A N D E A R L Y C H I C K P E R F O R M A N C E S. C O N S E Q U E N C E S OF COMBINING 24D WITH PICLORAM AND EXTREMES IN CONTAMINATION (BULL ENVIRON CONTAM TOXICOL 11(6) 511-516). REINHART BS EFFECT OF EXTERNAL APPLICATION OF PESTICIDES TO THE FERTILE EGO ON H A T C H I N G S U C C E S S A N D E A R L Y C H I C K P E R F O R M A N C E 2. C O M M E R C I A L HERBICIDE MIXTURES OF 24D WITH PICLORAM OR 245T USING THE PHEASANT (BULL ENVIRON CONTAM TOXICOL 11(4) 339-342). REINHART BS EFFECT OF EXTERNAL APPLICATION OF PESTICIDES TO THE FERTILE EGG ON H A T C H I N G S U C C E S S A N D E A R L Y C H I C K P E R F O R M A N C E 1. P R E - I N C U B A T I O N SPRAYING WITH DDT AND COMMERCIAL MIXTURES OF 24D - PICLORAM AND 24D - 245T (BULL ENVIRON CONTAM TOXICOL 11(1) 33-38). REINHART BS STEPHENSON GR EFFECT OF EXTERNAL APPLICATION OF 24D AND PICLORAM TO THE FERTILE EGG ON HATCHING SUCCESS AND EARLY CHICK PERFORMANCE (DOWN EARTH 29(3), 15-17). REINHART BS DOW EFFECT OF HERBICIDES ON BACTERIAL GROHTH RATES (APPL MICROBIOL 23,431-432). CLEMSON UNIV LYMPHOCYTE CHROMOSOME ANALYSIS OF AGRICULTURAL HORKERS DURING EXTENSIVE OCCUPATIONAL EXPOSURE TO PESTICIDES (MUTAT RES 21, 335-340). BENSON WW NUMBER j DOCUMENT 91 ^ DATE 00/00/76 AUTHOR ADDRESSEE COPYEE TORRACCA AM RASCHETTI R DOCUMENT 92 \ / 00/00/76 AUTHOR TOMKINS DJ ADDRESSEE COPYEE / DOCUMENT 93x7 00/00/76 AUTHOR TOMKINS DJ ADDRESSEE COPYEE DOCUMENT 99 00/00/68 AUTHOR SAHAMURA S ADDRESSEE COPYEE DOCUMENT 95 / 00/00/72 AUTHOR MIKHNO AN ADDRESSEE COPYEE DOCUMENT 96 j / 00/00/79 AUTHOR HAMEED KM ADDRESSEE' COPYEE DOCUMENT 97 \ J 00/00/76 AUTHOR GUERZONI ME ADDRESSEE COPYEE TYPE PAGES 1 V/ CARDAMONE GC RICCIARDI G / 1 GRANT WF 1J JACKSON HT 1y MUSIYAKA VK 1Y FOY CL iY DELCUPOLO L !/ TITLE PAGE 15 MUTAGENICITY OF PESTICIDES AS PURE COMPOUNDS AND AFTER METABOLIC A C T I V A T I O N H I T H RAT L I V E R M I C R O S O M E S t A T T I A S S O C G E N E T ITAL 21, 28-29). ORTALI V CARERE A EFFECTS OF HERBICIDES ON HILD PLANTS AT CHROMOSOMAL, POPULATION, AND COMMUNITY LEVELS (DISS ABSTR INT B 36,5925). MONITORING NATURAL VEGETATION FOR HERBICIDE INDUCED CHROMOSOMAL ABERRATIONS (MUTAT RES 36(1), 73-83). MCGILL UNIV QUEBEC CYTOLOG1CAL STUDIES IN VIVO OF PICLORAM, PYRICLOR, TR1FLURALIN, 2,3,6-TBA, 2,3,5,6-TBA AND NITRALIN (CYTOLOGIA 33,545-554). MITOTIC ACTIVITY OF CELLS DURING TREATMENT HITH 4-AMIN0-3,5,6-TRICHLOROPICOLINIC ACID (TSITOL GENET 6,516-519). K A L I N I N FL EFFECT OF PICLORAM ON THE GROHTH OF FIVE SOIL FUNGI (BULL COLL SCI U N I V B A G H D A D 15, 13-19). UNIV BAGHDAD IRAQ MUTAGENIC ACTIVITY OF PESTICIDES (RIV SCI TECNOL ALIMENTI NUTR UM 6(3), 161-165). PONTI I UNIV BOLOGNA ITALY NUMBER . DATE DOCUMENT 98 \/ 00/00/77 AUTHOR' ERCEGOVICH CD ADDRESSEE COPYEE' DOCUMENT 99 'f 00/00/75 AUTHOR' DELEIRE M ADDRESSEE' COPYEE' / DOCUMENT 100 '/ 00/00/78 AUTHOR CARERE A RASCHETTI R ADDRESSEE' COPYEE' DOCUMENT 101 ' 00/00/76 AUTHOR' CARERE A DIGIUSEPPE G ADDRESSEE' COPYEE' DOCUMENT 102 v / 00/00/77 AUTHOR> BIGNAMI M MORPURGO G ADDRESSEE' COPYEE' DOCUMENT 103 \y 00/00/76 AUTHOR' AULICINO F MORPURGO 0 ADDRESSEE' COPYEE' DOCUMENT 104 V 00/00/66 AUTHOR' ARNOLD HR ADDRESSEE' COPYEE' -T-Y-P-E-----------P-A-G-ES RASHID KA TITLE PAGE 16 MUTAGENESIS INDUCED IN MUTANT STRAINS OF SALMONELLA TYPHIMURIUM BY PESTICIDES (AMER CHEM SOC ABSTR PAP 174PEST A3). DECAT H / APPLICATION OF SIX BIOTESTS TO THE DETECTION OF HERBICIDES IN HATER (REV AGRIC (BRUSSELS) 1, 27-38). BASTIN R 1 MICROBIOLOGICAL MUTAGENICITY STUDIES OF PESTICIDES IN VITRO (MUTAT RES 57(3), 277-286). ORTALI VA CARDAMONE G TORRACCA AM 1ST SUPER SANIT ROME ITA CARDAMONE G J MUTATIONAL STUDIES HITH SOME PESTICIDES IN STREPTOMYCES COELICOLOR AND SALMONELLA TYPHIMURIUM (MUTAT RES 38(2), 136). ORTALI V BRUZZONE ML 1 \ MUTAGENIC AND RECOMBINOGENIC ACTION OF PESTICIDES IN ASPERGILLUS V' NIDULANS (MUTAT RES 46(6), 395-402). AULICINO F VELCICH A CARERE A 1ST SUPERIORE DI SANIT BIGNAMI M VELCICH A 1 V' MUTATIONAL STUDIES WITH SOME PESTICIDES IN ASPERGILLUS NIDULANS (MUTAT RES 38(2), 138) CARERE A CONTI G 1V SANTELMANN PH PICLORAM AND 24D EFFECTS HITH ASPERGILLUS NIGER PROLIFERATION (WEEDS 14(1 ),89-90). LYND JQ OK AGR EXPT STA NUMBER DATE DOCUMENT IOy - 00/00/72 AUTHOR: ADDRESSEE: COPYEEi DOCUMENT ANDERSEN KF J106 00/00/69 AUTHOR: P A L M E R ,JS ADDRESSEE COPYEE: DOCUMENT 107 / 00/00/70 AUTHOR' MACLEAN GJ JR ADDRESSEE COPYEE: DOCUMENT 10 V 7 00/00/69 AUTHOR: KUTSCHINSKI AH ADDRESSEE COPYEE: DOCUMENT 109 00/00/70 AUTHOR KUTCHES AJ ADDRESSEE: COPYEE: DOCUMENT 110 l/ 00/00/66 AUTHOR: JACKSON JB ADDRESSEE: COPYEE: DOCUMENT 111 '/ 00/00/65 AUTHOR: FISHER DE LISK DJ ADDRESSEE: COPYEE: V) <o CO TYPE PAGES 1 LEIGHTY EG 11 RADELEFF RD DAVIDSON JH JR RILEY V CHURCH DC / 1/ DOW STJOHN LE JR CORNELL UNIT TITLE PAGE 17 EVALUATION OF HERBICIDES FOR POSSIBLE MUTAGENIC PROPERTIES (J AGRIC FOOD CHEM 20, 649-656). TAKAHASHI MT THE TOXICITY OF SOME ORGANIC HERBICIDES TO CATTLE, SHEEP AND 1 CHICKENS (US DEPT AGR PROD RES REPT 106, 1-26). USDA DIAGNOSIS OF DISORDERS IN PASTURED LIVESTOCK (IND VEGETATION MANAGEMENT 2(2), 11-15). DOW RESIDUES IN VARIOUS TISSUES OF STEERS FED 4-AMINO-3,5,6-TRICHLOROPICOLINIC ACID (J AGR FOOD CHEM 17(2) 283-287). TOXICOLOGICAL EFFECTS OF PESTICIDES ON RUMEN FUNCTION IN VITRO (J AGRIC FOOD CHEM 18(3), 430-433). DURYEE FL OR ST UNIV TOXICOLOGIC STUDIES ON A NEH HERBICIDE IN SHEEP AND CATTLE (AM J BET RES 27(118), 821-824). FATE OF BANVEL T, IOXYNIL, TORDON, AND TRIFLUORILIN IN THE DAIRY DOH (J DAIRY SCI 48(12), 1711-1715). GUTENMANN WH WAGNER DO NUMBER DATE DOCUMENT 11z J 00/00/71 AUTHOR) SERGEANT M MORRE DJ ADDRESSEE' COPYEE) 1 DOCUMENT 113^ 00/00/79 AUTHOR) NISHIUCHI Y ADDRESSEE) COPYEE) / DOCUMENT 114 / 00/00/77 AUTHOR) FOGELS A ADDRESSEE' COPYEE) DOCUMENT 115 y 00/00/65 AUTHOR) COPE FG ADDRESSEE) COPYEE) DOCUMENT 116 V/ 00/00/74 AUTHOR: SUSCHETET M ADDRESSEE: COPYEE: JDOCUMENT 117 00/00/73 AUTHOR: SUSCHETET M ADDRESSEE' COPYEE) DOCUMENT U S ' / 00/00/79 AUTHOR: RUBEN FL ADDRESSEE' COPYEE: V>) 1 *O .* " \ H* 00 TYPE PAGES 1 BLAZEK D PURDUE UNIV ASANO K 1 SPRAGUE JB 1 1 V" LECLERC J y 1 CAUSERET J 1 1y MONTEFIORE HOSPITAL TITLE PAGE 18 TOXICITY OF 24D AND PICLORAN HERBICIDES TO FISH (PROC INDIANA ACAD SCI 80, 114-123). ELDER JH LEMBI CA TOXICITY OF PESTICIDES TO SOME FRESHHATER ORGANISMS (SUISAN ZOSHOKU 27(1) 48-55). NORIN SUISANSHO NOYAKU K COMPARATIVE SHORT TERM TOLERANCE OF ZEBRAFISH, FLAOFISH, AND RAINBOW TROUT TO FIVE POISONS INCLUDING POTENTIAL REFERENCE TOXICATS (HATER RES 11(9), 811-817). UNIV GUELPH ONTARIO TOXICITY OF TORDON 101 TO RAINBOW TROUT (PESTICIDE PROG 3(4), 89-90). TOXICITY AND NUTRITIONAL EFFECTS IN THE RAT OF TWO HERBICIDES, PICLORAM AND ATRAZINE (ANN NUTR ALIMENT 28(1), 29-47). UHUISSIER M LDISEL H PHYSIOPATHOLOGICAL AND NUTRITIONAL EFFECTS OF 4-AMINO-3,5,6-TRICHLOROPICOLINIC ACID (PICLORAM) IN THE RAT (C R ACAD SCI SER D 276(11),1775-1777). INST NATL RECH AGRON DIJ RECENT DEVELOPMENTS AND CONTRIBUTIONS FROM EXPERIMENTAL MODELS OF REYE'S SYNDROME (REYE'S SYNDROME 11,385-397). PITT NUMBER / DATE DOCUMENT 119 00/00/78 AUTHOR ROBENS JF ADDRESSEE* COPYEE DOCUMENT 120 v / 00/00/78 AUTHOR! NATL CANCER INST ADDRESSEE! COPYEE! DOCUMENT 121 V 00/00/70 AUTHOR! MOGILEVCHIK ZK ADDRESSEE! COPYEE: / DOCUMENT 122 ^ 00/00/69 AUTHOR! MCCOLLISTER DD ADDRESSEE COPYEE! DOCUMENT 123 00/00/72 AUTHOR MAILMAN RB ADDRESSEE! COPYEEs DOCUMENT 124 V 00/00/79 AUTHOR: KRAYBILL HF ADDRESSEE! COPYEE / DOCUMENT 125 ^ 00/00/75 AUTHOR: KOSACHEVSKAYA PI ADDRESSEE: COPYEE: VO H-4, Vr^ CO TYPE PAGES W TRACOR JITCO INC IV RUSYAEV A 1\ LENG ML 1 ;r HODGSON E 1 1` NATL CANCER INST BARAN NI 1 TITLE PAGE 19 TESTS FOR POSSIBLE CARCINOGENICITY OF 20 PESTICIDES IN OSBORNE MENDEL RATS AND B6C3F1 MICE (TOXICOL APPL PHARMACOL 45(1), 236). BIOASSAY OF PICLORAM FOR POSSIBLE CARCINOGENICITY (NCI TECH REP SER 23). IMPORTANCE OF NONSPECIFIC MANIFESTATIONS OF PESTICIDE POISONING IN SETTING NORMS FOR THEIR RESIDUAL QUANTITIES (VOP GIG TOKSIKOL PESTITS TR NAUCH SE, 49-51). VYALCHANNIKOV KA BUSLOVICH SY TOXICOLOGY OF PICLORAM AND SAFETY EVALUATION OF TORDON HERBICIDES (DOWN EARTH 25(2), 5-10). DOW CYTOCHROME P-450 SUBSTRATE OPTICAL DIFFERENCE SPECTRA OF PESTICIDES WITH MOUSE HEPATIC MICROSOMES (BULL ENVIRON CONTAM TOXICOL 8(3), 186-192). NC STATE UNIV BY APPROPRIATE METHODS THE DELANEY CLAUSE (ECOTOXICOL ENVIRON QUAL (2), 61-82). HYGIENIC EVALUATION OF WATER AFTER SOIL TREATMENT HITH THE PESTICIDE TORDON 22K (VRACH DELO 1, 131-133). NUMBER DATE -------- -------- - ---- --y ---------------------- DOCUMENT 126 \J 00/00/72 AUTHOR HODGSON E ADDRESSEE COPYEE DOCUMENT 127 ^ 00/00/79 AUTHOR CROUCH E ADDRESSEE: COPYEE! DOCUMENT 128 s j 00/00/75 AUTHOR BURCHFIELD HP ADDRESSEE COPYEE: DOCUMENT 129 \ / 00/00/71 AUTHOR BELOV LG ADDRESSEE! COPYEE: DOCUMENT 00/00/71 AUTHOR BELOV LG ADDRESSEE COPYEE DOCUMENT 131 00/00/72 AUTHOR GALSTON AH ADDRESSEE COPYEE: / DOCUMENT 132V* 00/00/70 AUTHOR GLASON AH ADDRESSEE: COPYEE TYPE PAGES 1 MAILMAN RB HILSON R 1 \/ STORRS EE 1 l/ ./ GULF SOUTH RES INST y O CO o TITLE PAGE T H E C Y T O C H R O M E P -450 S U B S T R A T E O P T I C A L DIFFERENCE S P E C T R A OF PESTICIDES WITH MOUSE HEPATIC MICROSOMES (BULL ENVIRON CONTAM TOXICOL 8(3), 186-192). 20 INTERSPECIES COMPARISON OF CARCINOGENIC POTENCT (J TOXICOL ENVIRON HEALTH 5(6), 1095-1118). HARVARD UNIV THE MAXIMUM TOLERATED DOSE IN PESTICIDE CARCINOGENICITY STUDIES (ENVIRON DUAL SAF SUPPL VOL 3 ISS PESTICIDES, 599-603). KRAYBILL HF ON THE TOXICOLOGICAL AND HYGIENIC EVALUATION OF THE HERBICIDE 4-AMINO-3 5>6-TRICHL0R0PIC0LINIC ACID (TORDON 22K PICLORAM) (HYG SANIT 36(3), 466-469). TOXICOLOGICAL AND HYGIENIC EVALUATION OF THE 4-AMINO-3,5,6-TRICHLOROPICOLINIC ACID (TORDON 22K) HERBICIDE (GIG SANIT 36(3), 112). SCIENCE AND SOCIAL RESPONSIBILITY A CASE HISTORY(ANN N Y ACAD SCI 196(4), 223-235). PLANTS, PEOPLE AND POLITICS (BIOSCIENCE 20(7), 405-410). NUMBER DOCUMENT 133 - / DATE 00/00/60 TYPE AUTHOR HORLD HEALTH ORGANIZATIO ADDRESSEE COPYEE PAGES 1j ' DOCUMENT 00/00/72 AUTHOR NESTING AH ADDRESSEE COPYEE 1 'J DOCUMENT 135 ^ 00/00/73 AUTHOR NEILANDS JB ADDRESSEE COPYEE 1V DOCUMENT AUTHOR ADDRESSEE COPYEE 00/00/73 DOCUMENT 137 00/00/74 AUTHOR SHOEMAKER JP ADDRESSEE COPYEE DOCUMENT 00/00/74 AUTHOR BRADLEY RL ADDRESSEE COPYEE BRADLEY RL 1 v' SHOEMAKER JP D OC U M E N T 139 x/ 0 0 / 0 0 / 7 2 1V AUTHOR ADDRESSEE COPYEE THOMPSON DJ ROBINSON VB EME R S O N JL TITLE PAOE 21 H E A L T H AS P E C T S OF C H E M I C A L A N D BIOLOGICAL WEAPONSJ REPORT OF A HHO GROUP OF CONSULTANTS. HERBICIDES IN WAR CURRENT STATUS AND FUTURE DOUBT (BIOL CONSERV <(5), 322-327). SURVEY OF CHEMICAL AND RELATED WEAPONS OF WAR (NATURWISSENSCHAFTEN 60, 177-183). DEGREE OF HAZARD WHEN USING HERBICIDES (S AFR SUGAR J 57(2), 71). DIRECT INJECTION OF EXPERIMENTAL MAMMARY ADENOCARCINOMA WITH PICLORAM (AM J MED SCI 268(6), 333-335). HOFFMAN RV JR TREATMENT OF EXPERIMENTAL MAMMARY ADENOCARCINOMA HITH HERBICIDES (CANCER CHEMOTHER 58(5), 7A5-748). HOFFMAN RV TERATOLOGY AND POSTNATAL STUDIES ON A - A M I N O - 3 , 5 6 - T R I C H L O R O P I C O L I N I C A C I D ( P I C L O R A M ) COSMET TOX 10(6), 797-803). STREBING RJ GERBIG CG IN THE RAT (FOOD NUMBER / DATE DOCUMENT AUTHOR: ADDRESSEE COPYEE! DOCUMENT 140^ 00/00/00 AULICION F MORPURGO G / V 141 00/00/00 AUTHOR! ADDRESSEE COPYEE CARERE A DIGIUSEPPE G DOCUMENT 142 ^ 00/00/77 AUTHOR ADDRESSEE COPYEE! BIGNAMI M MORPURGO G DOCUMENT y 143 08/00/79 AUTHOR ADDRESSEE COPYEE-' MORPURGO B CRESCENZI OS DOCUMENT 144 \ X 12/30/65 A U T H O R i OLSON KJ ADDRESSEE! COPYEE: DOCUMENT 145 04/01/63 AUTHOR! ADDRESSEE! COPYEE! DOCUMENT AUTHOR! ADDRESSEE COPYEE: JACKSON JB / / ,7 146 ^ 01/31/63 HILLIAMS RC o io ro TYPE PAGES BIGNAMI M VELCICH A TITLE PAGE 22 MUTATIONAL SUTDIES WITH SOME PESTICIDES IN ASPERGILLUS NIDULANS. CARERE A CONTI G ISTITUTO SUPERIORE DI SA 2^ CARDAMONE G ISTITUTO SUPERIORI MUTATIONAL STUDIES HITH SOME PESTICIDES IN STREPTOMYCES COELICOLOR AND SALMONELLA TYPHIMURIUM. ORTALI V BRUZZONE ML DI SA AULICINO F UNIV DI ROMA ITALY MUTAGENIC AND RECOMBINOGENIC ACTION OF PESTICIDES IN ASPERGILLUS NIDULANS (MUTATION RESEARCH 46, 395-402). VELCICH A CARERE A ISTITUTO SUPERIORE DI SA / BELLINCAMPI D ISTITUTO DELLORTO ANALYSIS OF MITOTIC NONDISJUCTION HITH ASPER6ILLUS (ENVIRON HEALTH PERSPECTIVE 31, 81-93). GUALANDI G BALDINELLI L BOTANI ISTITUTO SUPERIORE DI SA NIDULANS ARNOLD JE 20 TOXICOLOGICAL PROPERTIES AND INDUSTRIAL HANDLING HAZARDS OF ELEVEN TORDON PROCESS SAMPLES BC T35.12 38323-10. SILVERSTEIN LG DOH 15 v / TOXICOLOGY EVALUATION OF K-38323 (PICOLINIC ACID 4-AMIN0-3,5,6-TROCHLORO)TA-224. DOH G A N T Z RL ,,y FISH TOXICITY OF L U I TA-222 DOH NUMBER DATE DOCUMENT 147 08/23/65 AUTHOR STEVENSON OT ADDRESSEE' COPYFE DOCUMENT 06/20/63 AUTHOR' LYNN GE ADDRESSEE' COPYEE' DOCUMENT 00/00/77 AUTHOR NATL CANCER INST ADDRESSEE COPYEE' DOCUMENT / 150 V AUTHOR' HEW ADDRESSEE COPYEE' 02/07/78 DOCUMENT 151 01/30/78 AUTHOR ADDRESSEE COPYEE- MCCARTY WM MOOLENAAR RJ DOCUMENT 152 05/16/80 AUTHOR' TOLLETT JT DITTENBER DA SCHWETZ BA ADDRESSEE' COPYEE / DOCUMENT 1 5 3 v 02/04/80 AUTHOR' ADDRESSEE' COPYEE' NOLAN RJ DOW V) O ro A N> TYPE PAGES 24 S TOC K BL 1^ DOW S' 1y i^ 22 ALEXANDER HC KOCIBA RJ HERMANN EA SMITH FA BRAUN WH 42 TITLE PAGE 23 A GAMEBIRD TOXICOLOGY STUDY - ACUTE DIETARY FEEDING OF TORDON TO WILD TYPE MALLARD DUCKLINGS GH-A-119. DOW PICOLINIC ACID A-AMIN0-3 56-TRICHLORO- TORDON REQUEST FOR SCREENING OR APPLICATION TESTING. BIOASSAY OF PICLORAM FOR POSSIBLE CARCINOGENICITY (NATL TECH INFORM SERV PB-276A71i9AP)(PESTICIDE ABSTRACTS 78-2158). HEW NEWS (REPORT ON ANIMAL TESTS OF PICLORAM FOR CANCER CAUSING ACTIVITY RELEASED). COMPARATIVE TOXICITY OF THREE SAMPLES OF TECHNICAL PICLORAM CONTAINING VARIOUS AMOUNTS OF N"-(3,A56-TETRACHL0R0-2-PYRIDINYL) GUANIDINE TO BLUEGILL ES-200. DOW PARK CN PICLORAM RESULTS OF A 32 DAY TOXICITY TOLERANCE IN FEED IN B6C3F1 MICE HET K-038323-(lA). WADE CE MORDEN DC GORZ1NSKI SJ DOW KINETICS OF CIA - LABELED PICLORAM IN MALE FISCHER 3A4 RATS HET K-38323-(22). MULLER CJ CURL TC NUMBER DOCUMENT 154 / DATE 02/00/72 TYPE PAGES / 15 J AUTHOR ADDRESSEE! COPYEE! HEATH RO PATUXENT WILDLIFE / SPANN RESEAR USDI JW DOCUMENT 155 ^ 09/00/70 J27 AUTHOR: ADDRESSEE COPYEE: DOCUMENT W EIMER JT DEPT OF THE ARMY / 156 00/00/69 BALLARD TA 1 AUTHOR KUTSCHINSKI A ADDRESSEE COPYEE DOW DOCUMENT 157 ^ 00/00/69 AUTHOR ADDRESSEE COPYEE DOCUMENT KUTSCHINSKI AH / 158 00/00/72 AUTHOR: ADDRESSEE: COPYEE: DOCUMENT BAUR J / / 159 ^ 00/00/69 AUTHOR: KUTSCHINSKI AH ADDRESSEE COPYEE: DOCUMENT / 160 V 09/26/77 RILEY V BOVEY RW wy y 1 2 v' DOW 2V AUTHOR: CLEARINGHOUSE ON ENVIRON ADDRESSEE" COPYEE: V) s- I TITLE PAGE 24 C O M P A R A T I V E D I E T A R Y T O X I C I T I E S O F PESTICIDES TO BIRDS. SPECIAL SCIENTIFIC REPORT - WILDLIFE NO. 152. HILL EF KREITZER JF TOXICOLOGICAL STUDIES ON THE HERBICIDE WHITE IN ANIMALS. EDGEHOOD A R S E N A L T E C H N I C A L R E P O R T E A T R `439. OWENS EJ MCNAMARA BP RESIDUES IN MILK FROM COHS FED 4-AMIN0-3,5,6-TRICHLOROPICOLINIC A CID (JOUR AG FOOD C HEM 17 (2),288-290) (CHEM ABSTRACT) 113932. RESIDUES IN VARIOUS TISSUES OF STEERS FED 4 - A M I N 0 - 3 , 5 , 6 - T R I C H L O R O P I C O L I N I C A C I D (JOUR A G F OO D C H E M 17 (2),283-287)(CHEM ABSTRACTS) 113931T. DOW CONCENTRATION OF PICLORAM IN RUNOFF WATER 110345P (WEED SCIENCE 20(4),309-313). MERKLE MG TX A8M UNIV RESIDUES IN MILK FROM COWS FED 4-AMIN0-3,5,6-TRCHL0R0PIC0LINIC ACID 43807 (JOUR AG FOOD CHEM 17(2),288-290)(TOXICOLGY,4253-4254). REVIEW OF THE BIOASSAY OF PICLORAM FOR CARCINOGENICITY BY THE DATA EVALUATION / RISK ASSESSMENT SUBGROUP OF THE CLEARINGHOUSE ON ENVIRONMENTAL CARCINOGENS. NUMBER DATE DOCUMENT 161 06/12/62 AUTHOR) OLSON K ADDRESSEE) COPYEE) DOCUMENT 162 1 06/29/67 AUTHOR) KUTSCHINSKI AH ADDRESSEE) COPYEE) DOCUMENT AUTHOR) ADDRESSEE) COPYEE) 163y 00/00/00 REUBER MD DOCUMENT 164 \ / 12/00/74 AUTHOR) SHOEMAKER JP ADDRESSEE) COPYEE) DOCUMENT 165 00/00/84 AUTHOR) VESSEY DA ADDRESSEE COPYEE) DOCUMENT 166 01/15/84 AUTHOR) ADDRESSEE COPYEE) KAWASHIMA Y UCHIYAMA M DOCUMENT 03/00/82 AUTHOR) RIIHIMAK1 V ADDRESSEE COPYEE) O TO cn TYPE OYEN F PAGES 3 t/ TITLE PAGE 25 RESULTS OF ADDITIONAL ACUTE ORAL TESTS AND SKIN ABSORPTION STUDIES ON 4-AMINO 3,5/6-TRICHL0R0PIC0LINIC ACID TS5.12-38323-3. DON DON 1' RESIDUES OF TORDON ACID IN MILK FROM COHS FED THE HERBICIDE (GH-C 240 ). 38 \ / NATL CANCER INST CARCINOGENICITY OF PICLORAM. BRADLEY RL 3 V- DIRECT INJECTION OF EXPERIMENTAL MAMMARY ADENOCARCINOMA NITH PICLORAM - PRELIMINARY REPORT (AM JOUR MEDICAL SCIENCES 268(6), 333-335). HOFFMAN RV VA HOSPITAL HUNTINGTON N 9 DIFFERENTIAL ACTIVATION AND INHIBITION OF DIFFERENT FORMS OF RAT LIVER GLUTATHIONE S-TRANSFERASE BY THE HERBICIDES 24D AND 245T (TOX AND APPLIED PHARMACOLOGY 73, 492-499). BOYER TD VA MEDICAL CENTER SAN FR UNIV OF CA SAN FRANCISCO 6 EFFECT OF 24D AND 245T ON PEROXISOMAL ENZYMES IN RAT LIVER (BIOCHEMICAL PHARMACOLOGY 33(2), 241-245). KATOH H NAKAJIMA S KOZUKA H TOYAMA MEDICAL 8 PHARMAC NATL INST HYGIENIC SCIEN SISKO A 7 v MORTALITY OF 24D AND 245T HERICIDE APPLICATORS IN FINLAND (SCAND JOUR WORK ENVIRON HEALTH 8 (1), 37-42). HERNBERG S INST OCCUPATIONAL HEALTH NUMBER / DATE DOCUMENT 168 'J 00/00/85 AUTHOR SINGH SV ADDRESSEE COPYEE DOCUMENT 169 \j 08/00/84 AUTHOR MORTELMANS ADDRESSEE COPYEE / DOCUMENT 170 v 00/00/00 AUTHOR COURTNEY KD ADDRESSEE COPYEE DOCUMENT 171 v 10/00/84 AUTHOR RUBINSTEIN C MI ST UNIV ADDRESSEE COPYEE DOCUMENT 172 ^ 00/00/70 AUTHOR MESTRES R ADDRESSEE COPYEE / DOCUMENT 173 00/ 00/00 AUTHOR ADDRESSEE COPYEE DOCUMENT 174 02/10/70 AUTHOR FERNANSKY J ADDRESSEE COPYEE 'O \ ? O TO 1 TYPE PAGES 10 AWASTHI YC 1 10 8 JONE C 10 2 LEONARDI 0 TITLE PAGE 26 INHIBITION OF HUMAN GLUTATHIONE S-TRANSFERASES BY 24D AND 245T (TOX AND APPLIED PHARMACOLOGY 81, 328-336). UNIV OF TX MUTAGENICITY OF AGENT ORANGE COMPONENTS CTOX AND APPLIED PHAMACOLOGY 75C1), 138-145). 245T IN THE RAT ; EXCRETION PATTERN, SERUM LEVELS, PLACENTAL TRANSPORT, AND METABOLISM (PESTICIDES SYMPOSIA, 277-283HINCLUDES HANDWRITTEN GRAPH). INHIBITION OF INTERCELLUALR COMMUNICATION IN CULTURES OF CHINESE H A M S T E R V79 C E L L S BY 2 4 D A N D 2 4 5 T ( F U N D A M E N T A L A N D A P P L I E D T O X 4, 731-739). TROSKO JE CHANG CC P E S T I C I D E R E S I D U E S IN NAT U R A L H ATERS. 2. R E S I D U E S FROM CHLOROPHENOXY TYPE HERBICIDES. 2904D PESTICIDE RESIDUES FALS EXPERT C H I M 62 (686), 214-220) ( CHEM ABST R A C T S 73, (INCLUDES HANDWRITTEN LIST OF K NUMBERS). DUDIEUZEREPRICE M CHEVALIER MRS C XX (ANN 246) CHLOROPHENOXY HERBICIDES DRINKING HATER LIMITS 0.1 MG PER LITER (INCLUDES CHARACTERISTICS OF 3-0XA-5-DIAZABICYCL0(5.2.1)DECAN-4-0NE 5 - ( P - C H L 0 R 0 B E N Z 0 Y L ) - 1 0 - M E T H Y L , ). 24D K2372 REQUEST FOR PRELIMINARY TOXICOLOGICAL STUDIES NUMBER DOCUMENT 175 \/ DATE 04/13/70 AUTHOR: DUNN FL ADDRESSEE: COPYEE: DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 176 ^ T O D D RL / 00/00/62 DOCUMENT 177 v 00/00/00 AUTHOR: SHAFIK MT ADDRESSEE: COPYEE: DOCUMENT 178 00/00/65 AUTHOR: BERKLEY MC ADDRESSEE COPYEE: DOCUMENT 179 V 11/20/50 AUTHOR: ASSOULY M ADDRESSEE COPYEE: / DOCUMENT 180 00/00/85 AUTHOR: ADDRESSEE: COPYEE: YOUNG AL / DOCUMENT 181 ^ 00/00/85 AUTHOR: ADDRESSEE COPYEE: La DEVERNEUIL O J TYPE DOM PAGES 27 SULLIVAN HC MAGEE KR 5 ,,y SHEPARD BM SASSA S 7J TITLE PAGE 27 RESULTS OF CHLORACNE STUDIES CONDUCTED ON ASSORTED 24D, Z45T, SILVEX SAMPLES AND THEIR ESTERS ORANGE AND DIAMOND'S CROP RIDER AMINE 4T-2. A CASE OF 24D INTOXICATION (JOUR IOHA M E D SOC 52 663-664). A METHOD FOR DETERMINATION OF LOW LEVELS OF EXPOSURE TO 24D AND 245T. ENOS HF HEH NEUROPATHY FOLLOWING EXPOSURE TO A DIMETHLYAMINE SALT OF 24D (ARCH INT MED 111 351-352) DESHERBANTS SELECTIFS ET SUBSTANCES DE CROISSANCE. SPERCH TECHNIQUE. EFFET PATHOLOGIQUE SUR L'HOMME AU COURS DE LA FABRICATION DE L'ESTER DU 24D(COMOMUNICATION A LA SOCIETIE DE MEDICINE DU TRAVAIL, 26-30). A REVIEW OF ON GOING EPIDEMIOLOGIC RESEARCH IN THE UNITED STATES ON THE PHENOXY HERBICIDES AND CHLORINATED DIOXIN CONTAMINANTSiCHEMOSPHERE 12(4/5), 749-459). VETERANS ADMIN EFFECTS OF POLYCHLORINATED BIPHENYL COMPOUNDS, TCDD, PHENOBARBITAL AND IRON ON HEPATIC U R O PORPHYRINOGEN DE C A R B O X Y L A S E (BIOCHEM J 214, 145-151). KAPPAS A ROCKEFELLER UNIV HOSPITA NUMBER / DATE _J TYPE PAGES /, TITLE DOCUMENT AUTHOR ADDRESSEE COPYEE 182 V 00/00/82 8 ./ THE TOXICITY AND TOXIC POTENTIAL OF FLY ASH FROM MUNICIPAL v INCINERATORS ASSESSED BY MEANS OF A FISH EARLY LIFE STAGE TEST (CHEMOSPHERE 11(10), 965-972). HELDER T ST UNIV UTRECHT NETHERLA STUTTERHEIM E OLIE K UN1V AMSTERDAM NETHERLAN DOCUMENT 183 / 00/00/83 AUTHOR ADDRESSEE COPYEE RIZZARDINI M VECCHI A GARATTINI S ROMANO M SIRONI M FANELLI R 6 n/ TOXICOLOGICAL EVALUATION OF URBAN HASTE INCINERATOR (CHEMOSPHERE 12(4/5), 559-564). TURSI F SALMONA M GIZZI F BENFENATI E ISTITUTO RICERCHE FARMAC EMISSIONS DOCUMENT 184 / 00/00/81 14V AUTHOR ADDRESSEE COPYEE CLARK DA MCMASTER UNIV ONTARIO GAULDIE J ENHANCED SUPPRESSOR CELL ACTIVITY AS A MECHANISM OF IMMUNOSUPPRESSION BY TCDD (PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 168, 290-299)(INCLUDES PHOTOCOPY REQUEST FOR JOURNAL ARTICLES). SZEWCZUK MR SHEENEY 0 DOCUMENT 185 ^ 00/00/81 AUTHOR ADDRESSEE COPYEE: CATTANEO M CEFIS F / DOCUMENT 186 V 09/00/73 AUTHOR HUFF JE ADDRESSEE: COPYEE: DOCUMENT 187 00/00/73 AUTHOR: J I R A S E K LL ADDRESSEE: COPYEE: 14 V REMOTTI G UNIV MILANO ITALY REPERTI ISTOLOGICI PLACENTARI IN SOGGETTI PROVENIENTI DA AREA INQUINATA DA TCDD (OST GIN MED PERIN CII, 155-164) (PLACENTAL HISTOLOGY OF THE TCDD EXPOSED PREGNANT HOMEN). COVIELLO D CARINI A / HASSOM JS 30 CHLORINATED DIBENZODIOXINS AND DIBENZOFURANS (ENVIRONMENTAL HEALTH PERSPECTIVES, 283-312). BIOMEDICAL STUDIES TOX I OAK RIDGE NATL LAB KALENSKY J / 22 J ACNE CHLORINA AND PORPHYRIA CUTANEA TARDA DURING THE MANUFACTURE OF HERBICIDES (REPORT AND SUMMARY). KUBEC K O to CD NUMBER / DATE TYPE PAGES DOCUMENT 188 J 09/15/83 13 AUTHOR ADDRESSEE COPYEE TOFTGARD R GUSTAFSSON J UNIV STOCKHOLM SWEDEN LOFROTH G KAROLINSKI INST SNEDI DOCUMENT 09/00/83 AUTHOR C H R I S T I A N BJ ADDRESSEE COPYEE 15 y PETERSON RE DOCUMENT 190 J 00/00/83 8v AUTHOR I ADDRESSEE COPYEE MARINOVICH M UNIV MILANO ITALY SIRTORI CR DOCUMENT 191V 10/00/83 AUTHOR: ADDRESSEE COPYEE GASIEHICZ TA VANDERBILT UNIV RUCCI G DOCUMENT 192 V 07/00/83 AUTHOR THUNBERG T ADDRESSEE' COPYEE DOCUMENT 193 AUTHOR: DOH ADDRESSEE' COPYEE 00/ 0 0 /0 0 10 ( HAKANSSON H 5WA -(IL DO C U M E N T 194 N-/' 0 2 / 0 9 / 8 2 AUTHOR ADDRESSEE COPYEE O O CO 2^ TITLE PAGE 29 COMPOUNDS IN URBAN AIR COMPETE HITH TCDD FOR BINDING TO THE RECEPTOR PROTEIN (CHEMICO - BIOLOGICAL INTERACTIONS 96(3), 335-396). CARLSTEDTDUKE J KURL R IN H U D D I N G E UNIV H O S P I T A L S N O R D I C S C H O O L P U B L I C HEA EFFECTS OF TCDD ON (H)THYMIDINE INCORPORATION INTO RAT LIVER DEOXYRIBONUCLEIC ACID (TOXICOLOGY 28(1,2), 133-196). UNIV MI THE BINDING OF TCDD TO PLASMA LIPOPROTEINS MAY DELAY TOXICITY IN EXPERIMENTAL HYPERLIPIDEMIA (CHEMICO - BIOLOGICAL INTERACTIONS 95(3), 393-399). GALLI CL PAOLETTI R DISTRIBUTION, EXCRETION, AND METABOLISM OF TCDD IN D57BL/6J, DBA/2J, AND B6D2F/J MICE (DRUG METABOLISM AND DISPOSITION; THE BIOLOGICAL FATE OF CHEMICALS 11(5), 397-903. NEAL RA GEIGER LE VITAMIN A (RETINOL) STATUS IN THE GUNN RAT (ARCHIVES OF TOXICOLOGY 53(3), 225-233). KAROLINSKA INST STOCKHOL CALCULATION OF APPROPRIATE HEALTH STANDARD FOR TCDD IN DRINKING MATER AND FISH (USING ADI ESTABLISHED BY DUTCH GOVERNMENT). DIOXINE NOT A COMPLETE CARCINOGEN (DIOXINE NIET VOLLEDIG KANKERVERMEKKEND)(STAATSCOURANT)(ORIGINAL NEMS ARTICLE AND TRANSLATION). W /r-(T NUMBER DATE DOCUMENT 195 00/00/83 AUTHOR: ZIEM O ADDRESSEE COPYEE! DOCUMENT 196^/ 04/00/79 AUTHOR TOTH K ADDRESSEE! COPYEE: DOCUMENT 197 ^ 00/00/83 AUTHOR: ADDRESSEE: COPYEE: BOND GG DOW DOCUMENT 198 y / 00/00/83 AUTHOR: THUNBERG T ADDRESSEE: COPYEE: DOCUMENT 199 V 00/00/83 AUTHOR: ZIEM G ADDRESSEE: COPYEE: DOCUMENT Z O O ' / 03/00/83 AUTHOR: ADDRESSEE: COPYEE: YANG KH / DOCUMENT 201 V 07/00/84 AUTHOR: ADDRESSEE: COPYEE: SHARMA RP DOW O CO o TYPE PAGES 1^ JOHNS HOPKINS UNIV TITLE PAOE 30 TETRACHLOROD1BENZODIOXIN (BRITISH JOURNAL OF INDUSTRIAL MEDICINE AO, 116). MAY G 2y SOMFAIREILL S CARCINOGENICITY TESTING OF HERBICIDE 2,A,5-TRICHL0R0PHEN0XYETHAN0L CONTAINING DIOXIN AND OF PURE DIOXIN IN SHISS MICE. SUGAR J ILLEGIBLE OTT MG 8 MEDICAL AND MORBIDITY SURVEILLANCE FINDINGS AMONG EMPLOYEES POTENTIALLY EXPOSED TO TCDD (BRITISH JOURNAL OF INDUSTRIAL MEDICINE AO, 318-324). BRENNER FE COOK RR 5v- S T U D I E S ON T H E E F F E C T OF T C D D ON V I T A M I N A; A N E W A S P E C T C O N C E R N I N G THE MECHANISM OF TOXICITY. KAROLINSKA INST STOCKHOL 2/ JOHNS HOPKINS UNIV TETRACHLORODIBENZODIOX1N (BRITISH JOURNAL OF INDUSTRIAL MEDICINE AO, 116). MAY G CHOI EJ CYTOTOXICITY OF TCDD ON PRIMARY CULTURES OF ADULT RAT HEPATOCYTES (ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 12(2), 183-188). CHOE SY KOREA ADVANCED INST SCIE UT ST UNIV IMMUNOTOXICOLOGIC EFFECTS OF TCDD IN RABBITS (JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY 5(A/5), 321-328). KOCIBA RJ GEHRING PJ NUMBER /D AT E DOCUMENT 202 V 11/00/84 AUTHOR: SEEFELD MD ADDRESSEE COPYEE DOCUMENT / 203 V 10/00/84 AUTHOR: MANARA L ADDRESSEE: COPYEE: TYPE PAGES ^ TITLE PAGE 31 KEESEY RE 12 \ / BODY HEIGHT REGULATION IN RATS TREATED WITH TCDD (TOXICOLOGY AND APPLIED PHARMACOLOGY 76, 526-536). PETERSON RE UNIV HI COCCIA P PREVENTION OF TCDD TOXICITY IN LABORATORY RODENTS BY ADDITION OF CHARCOAL OR C H O LIC AC ID S TO CHOH (FOOD AND CHEMICAL TOXICOLOGY 22(10), 815-818). CROCI T ISTITUTO RICERCHE FARMAC DOCUMENT 204 00/00/84 AUTHOR: ADDRESSEE COPYEE: KIMBROUGH RD FRIES G FALK H USDA 48 r HEALTH IMPLICATIONS OF TCDD CONTAMINATION OF RESIDENTIAL SOIL (JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 14(1), 47-93. STEHR P US DEPT HEALTH HUMAN SER D O C U M E N T 205 V ^O0O0 / 0 0 / 8 4 AUTHOR ADDRESSEE: COPYEE PRATT RM UPPSALA UNIV SWEDEN DENCKER L UNIV BRITISH 11 T C D D I N D U C E D C L E F T P A L A T E IN T H E MOUSE E V I D E N C E FOR A L T E R A T I O N S IN PALATAL SHELF FUSION (TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS 4(5), 427-436). DIENERT VM NATL INST OF HEALTH COLUMBIA DOCUMENT 206 00/00/84 AUTHOR ADDRESSEE CUPYEE: ROZMAN K / DOCUMENT 207 ' J 03/00/84 UNIV KS AUTHOR: ADDRESSEE: COPYEE: THUNBERG T NATL FOOD ADMIN UPPSALA AHLBORG UG 8V- ' SEPARATION OF HASTING SYNDROME AND LETHALITY CAUSED BY TCDD (TOXICOLOGY LETTERS 22(3), 279-285). s 6/ COMPARISON BETHEEN THE EFFECTS OF TCDD AND SIX OTHER COMPOUNDS ON THE VITAMIN A STORAGE, THE UCP-GLUCURONOSYLTRANSFERASE AND THE ARYL HYDROCARBON HYDROXYLASE ACTIVITY IN THE RAT LIVER (ARCHIVES OF TOXICOLOGY 55(1), 16-19). HAHLSTROM B KAROL INSKI INST STOCKHOL O OJ NUMBER V -DOCUMENT 208' DATE 10/00/85 AUTHOR ADDRESSEE COPYEE DOCUMENT ROZMAN K PARKINSON A / 209 00/00/85 AUTHOR SUTERHOFMANN M ADDRESSEE COPVEE DOCUMENT AUTHOR ADDRESSEE COPYEE ./ 210 00/00/85 SUTERHOFMAN M DOCUMENT /211 V 11/00/81 AUTHOR CHEUNG MO ADDRESSEE' COPYEE TYPE PAGES 14 7 * HAZELTON GA UNIV KS TITLE PAGE 32 E F F E C T OF T H Y R O I D H O R M O N E S ON L I V E R MICROSOMAL E N Z Y M E INDUC T I O N IN RATS EXPOSED TO TCDD (TOXICOLOOY 37, 51-63). KLAASSEN CD A R L O T T O MP 12 >/ SCHLATTER C TOXICITY OF PARTICULATE EMISSIONS FROM A MUNICIPAL INCINERATOR; CRITIQUE OF THE CONCEPT OF TCDD EQUIVALENTS. UNIV ZURICH SHITZERLAND 1 V CORRECTION OF DATA FOR 'DIOXIN 85' SEHT TO KOCIBA R C T T L . INSTITUT FR TOXIKOLOGIE GILBERT EF 9V CARDIOVASCULAR TERATOGENICITY OF TCDD IN THE CHICK EMBRYO (TOXICOLOGY AND APPLIED PHARMACOLOGY 61(2), 197-204). PETERSON RE UNIV MI DOCUMENT 2 1 2 > / 10/00/81 11V AUTHOR ADDRESSEE COPYEE MADHUKAR /" BV DOCUMENT 213 V 00/00/81 AUTHOR ADDRESSEE . COPYEE CANTONI FANELLI L R MATSUMURA F 10 RIZZARDINI M SALMONA M DOCUMENT 214 ^ 00/00/81 AUTHOR ADDRESSEE COPYEE VANLOGTEN MJ GUPTA NATL INST ENVIRON HEALTH BN O tw 13 DIFFERENCES IN THE NATURE OF INDUCTION OF MIXED FUNCTION OXIDASE SYSTEMS OF THE RAT LIVER AMONG PHENOBARBITAL, DDT, 3-METHYLCHOLANTHRENE, AND TCDD (TOXICOLOGY AND APPLIED PHARMACOLOGY 61(1), 109-118). MI ST UNIV INDUCTION OF MIXED FUNCTION OXIDASE BY CHRONIC TREATMENT WITH TCDD IN FEMALE RATS (TOXICOLOGY 21(2), 159-167). BELVEDERE G CANTONI R ISTITUTO RICERCHE FARMAC / THE INFLUENCE OF MALNUTRITION ON THE TOXICITY OF TCDD IN RATS (TOXICOLOGY 21(1), 77-88). MCCONNELL EE MOORE JA NUMBER DATE DOCUMENT 215 07/00/81 AUTHOR: ADDRESSEE COPYEE: S H I F T LI SOULE PD DOCUMENT 07/00/81 AUTHOR STEHARD AR ADDRESSEE: COPYEE DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 217 08/00/84 YASUDA M DOCUMENT y 218'' 00/00/83 AUTHOR CHRI ST I A N BJ ADDRESSEE COPYEE: X DOCUMENT 219 \ / 00/00/83 AUTHOR ADDRESSEE: COPYEE: KATZ LB / DOCUMENT 2 2 0 ^ 00/00/83 AUTHOR ADDRESSEE: COPYEE: HUDSON LG / DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 221 00/00/00 TYPE PAGES GASIEWICZ TA NEAL RA BYARD JL 15 IGAHA HH 2 X' PETERSON RE ,/ f 1 l' THEOBALD HM 1x TOSCANO HA JR lX TITLE PAGE 33 CHARACTERIZATION OF HYPERLIPIDEMIA IN GUINEA PIGS INDUCED BY TCDD (TOXICOLOGY AND APPLIED PHARMACOLOGY 59(3), 489-499). VANDERBILT UNIV DUNN GD INDUCTION OF BENZOiA)PYRENE METABOLISM BY TCDD IN PRIMARY CULTURES OF ADULT RAT HEPATOCYTES (TOXICOLOGY AND APPLIED PHARMACOLOGY 59(3), 603-616). UNIV CA DAVIS TERATOGENICITY OF TCDD IN MICE (TERATOLOGY 30(1), 12A). HIROSHIMA UNIV JAPAN THE ROLE OF REDUCED FOOD CONSUPTION IN THE LETHALITY OF TCDD TREATED RATS (PHARMACOLOGIST 25, 169). UNIV HI EFFECT OF ANTIINFLAMMATORY DRUGS ON THE ENHANCED EDEMA RESPONSE TO CARRAGEENAN AND DEXTRAN IN RATS TREA T E D W ITH TCDD (PHARMACOLOGY 25, 103) . PETERSON RE UNIV HI REGULATION OF EPIDERMAL GROWTH FACTOR BINDIHQ AND UPTAKE IN CULTURED HUMAN EPIDERMAL CELLS BY TCDD (FEDERAL PRODEEDINGS 42(7), 1988). GREENLEE HF HARVARD SCHOOL PUBLIC HE DIOXIN - ILLEGIBLE (PESTICIDE AND TOXIC CHEMICAL NEHS) NUMBER DOCUMENT AUTHOR! ADDRESSEE COPYEE: 222 DATE 00/ 00/00 DOCUMENT 223V 08/17/84 AUTHOR ADDRESSEE: COPYEE: ERICKSON JD JAMES LM TYPE PAGES TITIE ILLNESS ASSOCIATED HITH TCDD CONTAMINATED SOIL. PAGE 34 MULINARE J MCCLEARN AB y11 VIETNAM VETERANS* RISKS FOR FATHERING BABIES WITH BIRTH DEFECTS (JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 252(7), 903-912). MCCLAIN PH FITCH TG ADAMS MJ JR CENTERS FOR DISEASE CONT DOCUMENT 224 y ^ 0 6 / 3 0 / 8 4 AUTHOR: SEEFELD MD ADDRESSEE: COPYEE: 10 ^ PETERSON RE DIGESTIBLE ENERGY AND EFFICIENCY OF FEED UTILIZATION IN RATS TREATED WITH TCDD (TOXICOLOGY AND APPLIED PHARMACOLOGY 74(2), 214-222). UNIV HI DOCUMENT 225 AUTHOR: DAN BB ADDRESSEE COPYEE: 08/17/84 DOCUMENT V 226 00/00/84 AUTHOR: DARGY R ADDRESSEE: COPYEE: 3 VIETNAM AND BIRTH DEFECTS (JOURNAL OF THE AMERCICAN MEDICAL ASSOCIATION 252(7), 936). AMERCIAN MEDICAL ASSOC 7 HASSOUN E TERATOGENICITY OF TCDD AND THE CONGENER 3,3*,4,4*-TETRACHLOROAZOXYBENZENE IN SENSITIVE AND MOUSE STRAINS AFTER RECIPROCAL BLASTOCYST TRANSFER LETTERS 21, 197-202). DENCKER L UNIV UPPSALA SHEDEN NONSENSITIVE (TOXICOLOGY DOCUMENT 227 00/00/84 AUTHOR: MARTIN JV ADDRESSEE: COPYEE: 3^ LIPID ABNORMALITIES IN HORKERS EXPOSED TO DIOXIN (BRITISH JOURNAL OF INDUSTRIAL MEDICINE 41, 254-256). OLDHAM DISTRICT GENERAL DOCUMENT 02/00/84 AUTHOR: ADDRESSEE: COPYEE: ROZMAN K ROZMAN T BASOTHERM BMGH FED REPUB CO EFFECT OF THYROIDECTOMY AND THYROXINE ON TCDD INDUCED TOXICITY (TOXICOLOGY AND APPLIED PHARMACOLOGY 72(2), 372-376). GREIM H UNIV KS e ifrn NUMBER / DATE TYPE PAGES DO C U M E N T 229 '' 0 3 / 3 0 / 8 4 10 AUTHOR: ADDRESSEE: COPYEE: KOSHAKJI RP TN NEUROPSYCHIATIC INST HARBISON RD DOCUMENT 230 V 04/00/84 AUTHOR: SEEFELD MD UNIV HI ADDRESSEE: COPYEE: CORBETT SH 13 ^ DOCUMENT 231 v 03/30/84 7v AUTHOR: ADDRESSEE COPYEE: PUHVEL SM / DOCUMENT 2 3 2 ^ 06/15/84 AUTHOR: ADDRESSEE: COPYEE: GREIG JB SMITH AG ERTL DC 10 v FRANCIS JE MEDICAL RES COUNCIL DOCUMENT 233^' 06/15/84 AUTHOR: GEIRTHY JF ADDRESSEE COPYEE: CRANE D DOCUMENT 234 v 00/00/84 AUTHOR: ADDRESSEE: COPYEE: CANTONI L ISTITUTO RECERCHE FARMAC DALFIUME D P O CO en TITLE PAGE 35 STUDIES ON THE METABOLIC FATE OF 19C TCDD IM THE MOUSE (TOXICOLOGY AND APPLIED PHARMACOLOGY 73(1), 69-77). BUSH MT VANDERBILT UNIV CHARACTERIZATION OF THE HASTING SYNDROME IN RATS TREATED HITH TCDD (TOXICOLOGY AND APPLIED PHARMACOLOGY 73(2), 311-322). KEESEY RE PETERSON RE INCREASED EPIDERMAL TRANSGLUTAMINASE ACTIVITY FOLLOWING TCDD; IN VIVO AND IN VITRO STUDIES HITH MOUSE SKIN (TOXICOLOGY AND APPLIED PHARMACOLOGY 73(1), 92-97). LYNBERG CA UNIV CA LOS ANGELES INCOMPLETE CORRELATION OF TCDD HEPATOXICITY HITH AH PHENOTYPE IN MICE (TOXICOLOGY AND APPLIED PHARMACOLOGY 79(1), 17-25). KAY SJE LOVELL DP LAB REVERSIBLE INHIBITION OF IN VITRO EPITHELIAL CELL PROLIFERATION BY TCDD (TOXICOLOGY AND APPLIED PHARMACOLOGY 79(1), 91-98). NY ST DEPT HEALTH IN VITRO INHIBITORY EFFECT ON PORPHYRINOGEN CARBOXYLYASE OF LIVER EXTRACTS FROM TCDD TREATED M ICE (TOXI C O L O G Y LETTERS 20, 211-217). RIZZARDINI M RUGGIERI R NUMBER DOCUMENT 235 DATE 12/00/83 AUTHOR ADDRESSEE COPYEE HEBER 0 UNIV SIENA ITALY TYPE PAGES V* LUZI P LOVATI MR TITLE PAGE 36 NATURAL HISTORY OF TCDD INDUCED LIVER LESIONS IN RATS AS OBSERVED BY TRANSMISSION ELECTRON MICROSCOPY DURING A 32 HEEK PERIOD AFTER A SINGLE INTRAPERITONEAL INJECTION (JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 12(4-6), 533-540). RESI L TANGANELLI P POLI A UNIV MILAN ITALY DOCUMENT AUTHOR ADDRESSEE COPYEE 00/00/84 CANTONI L RUGGIERI R DOCUMENT 09/00/83 AUTHOR JACKSON S ADDRE5SEE COPYEE 11'/ DIFFERENT SUSCEPTIBILITY OF MOUSE TISSUES TO PORPHYROGENIC EFFECT OF TCDD (TOXICOLOGY LETTERS 20, 201-210). DAL FIUME D FERRAROLI A SALMONA M ISTITUTO RICERCHE FARMAC 12 v DIOXIN TOXICOLOGY (INCLUDING AGENT ORANGE)(NATIONAL LIBRARY OF MEDICINE LITERATURE SEARCH 83-19). US DEPT HEALTH AND HUMAN DOCUMENT 238 12/00/83 AUTHOR HASSAN MQ ADDRESSEE COPYEE: STOHS SJ lO'/ COMPARATIVE ABILITY OF TCDD TO INDUCE LIPID PEROXIDATION IN RATS, GUINEA PIGS, AND SYRIAN GOLDEN HAMSTERS (BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 31(6), 649-657). MURRAY HJ UNIV NB DOCUMENT AUTHOR ADDRESSEE: COPYEE 2 3 9 V 00/00/78 REHDER H MEDICAL HOCHSCHULE LUBEC 34 * SANCHIONI L ISTITUTI ELINICI DI PATHOLOGICAL EMBRYOLOGICAL INVESTIGATIONS IN CASES OF ABORTION RELATED TO THE SEVESO ACCIDENT (SCHWEIZERISCHE MEDIZINISCHE WOCHENSCHRIFT 108(42), 1617-1625). CEFIS F GROPP A PERF DOCUMENT 240 ^ 04/02/77 AUTHOR ADDRESSEE: COPYEE: BEALE MG WA UNIV ILLEGIBLE 2 S LONG TERM EFFECTS OF DIOXIN EXPOSURE (THE LANCET)(SEVESO INFO PACKET). KARL MM ROBSON AM O CO "CS-h NUMBER /' DATE TYPE PAGES TITLE PAGE 37 DOCUMENT AUTHORi ADDRESSEE COPYEEs 241V 00/00/77 LAB DI IGIENE E PROFILAS SCHOOL 23 s / ACTIVITY OF THE LPIP IN TESTING CONSEQUENT TO THE ICMESA INCIDENT (SEVESO INFO PACKET). OF AEROSPACE MEDI DOCUMENT X 242 00/00/77 AUTHOR: DI DOMENICO A ADDRESSEE! COPYEE! ISTITUTO 42^ SUPERIORE VALUTAZIONE DELLA TCDD NEL TERRENS SVILUPPO DELIA NETODELOGIA NANL I T I C A DEFINIZIONE DEL S I S T E M E DE A P P R O N T A M E N T O DI UNA MAPPA CONTAMINAZIONE (CHAPTER III - VI) (INCLUDES ATTACHMENTSH S E V E S O INFO PACKET). DI SA LAB PROVI N C I A L E DI IGIEN DI DOCUMENT 12/00/81 AUTHOR: ADDRESSEE: COPYEE: FILIPPINI G MUSICCO M / BORDO B BOERI R 7 ^ RELATIONSHIP BETWEEN CLINICAL AND ELECTROPHYSIOLOGICAL FINDINGS AND INDICATORS OF HEAVY EXPOSURE TO TCDD (SCANDINAVIAN JOURNAL OF WORK? ENVIRONMENT AND HEALTH 7(4), 257-262). CRENNA P MASSETTO N ISTITUTO NEUROLOGICO ITA DOCUMENT 244 ^ 00/00/81 AUTHOR: GREIG JB ADDRESSEE: COPYEE: OSBORNE G 6 BIOCHEMICAL AND MORPHOLOGICAL CHANGES INDUCED BY TCDD IN THE RAT LIVER CELL PLASMA MEMBRANE (JOURNAL OF APPLIED TOXICOLOGY 1(6), 334-338). MEDICAL RES COUNCIL LAB DOCUMENT 245V' 10/00/81 AUTHOR: BALL LM ADDRESSEE: COPYEE: CHHABRA RS 11 INTESTINAL ABSORPTION OF NUTRIENTS IN RATS TREATED WITH TCDD (JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 8(4), 629-638). NATL INST ENVIRON HEALTH DOCUMENT 246 00/00/81 AUTHOR: DENCKER L ADDRESSEE! COPYEE: PRATT RM 9 ^ ASSOCIATION BETWEEN THE PRESENCE OF THE AH RECEPTOR IN EMBRYONIC MURINE TISSUES AND SENSITIVITY TO TCDD INDUCED CLEFT PALATE (TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS 1(4), 399-406). NATL INST OF HEALTH e&H-CL^ DOCUMENT AUTHOR: ADDRESSEE: COPYEE 247 \ X 00/00/81 ARSTILA AU HIPF HK O CO / 6 ' E L I M I N A T I O N OF T C D D IN G O A T MI L K ( T O X I C O L O G Y L E T T E R S 9, 215-219). REGGIANI G SORVARI TE RAISANEN S NUMBER DATE DOCUMENT 248 00/00/83 AUTHOR i COOK RR ADDRESSEE: COPYEE: DOCUMENT 249 00/00/83 AUTHOR- ADDRESSEE) COPYEE: BOND GO DOM DOCUMENT 250 V 00/00/85 AUTHOR: ADDRESSEE) COPYEE: STEINBERG KK NEESE JM DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 03/18/81 DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 252 s- 0 2 / 0 2 / 7 3 POLAND A DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 253 V " 00/00/00 DOCUMENT 254 ' 00/00/86 AUTHOR: POTTER CL ADDRESSEE: COPYEE: O 00 00 TYPE PAGES -- "7 BODNER KM OTTMG 8x/ MACNEIL ML N E E D H A M LL 11 ^ 3 GLOVER E 2 1 10 \ MENAHAN LA TITLE PAGE 38 DIOXIN AND REPRODUCTIVE EVENTS (HUMAN AND ENVIRONMENTAL RISKS OF CHLORINATED DIOXINS AND RELATED COMPOUNDS, 593-603). DON MEDICAL AND MORBIDITY SURVEILLANCE FINDINGS AMONG EMPLOYEES POTENTIALLY EXPOSED TO TCDD (BRITISH JOURNAL OF INDUSTRIAL MEDICINE 40, 318-324). BRENNER FE COOK RR ASSESSMENT OF TCDD EXPOSURE USING A MODIFIED D-GLUCARIC ACID ASSAY (JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 16(6), 743-752). KARON JM STEHR PA US DEPT HEALTH HUMAN SER REPRODUCTIVE EFFECTS, WORKER CANCER STUDIES NOTED IN TSCA 8(E) REPORTS (PESTICIDE 8 TOXIC CHEMICAL NEWS, 8-10). TCDD A POTENT INDUCER OF A-AMINOLEVULINIC ACID SYNTHETASE!SCIENCE). UNIV OF ROCHESTER DIOXIN - ILLEGIBLE (PEST AND TOXIC CHEMICAL NEWS). RELATIONSHIP OF ALTERATIONS IN ENERGY METABOLISM TO HYPOPHAGIA IN R A T S T R E A T E D W I T H TC D D ( F U N D A M E N T A L A N D A P P L I E D T O X I C O L O G Y 6, 89-97). PETERSON RE UNIV HI  e > tr ~ ( NUMBER / DATE DOCUMENT 255 ^ 11/16/68 AUTHOR: ADDRESSEE COPYEE: HIGGINBOTHAM GR RESS J DOCUMENT 256V 00/00/83 AUTHOR' - ADDRESSEE: COPYEE: BOND DOH GG / DOCUMENT 257 v 00/00/81 AUTHOR BICKERS DR ADDRESSEE COPYEE: DOCUMENT 258 ^ 00/00/82 AUTHOR BIGELOW NICHD A D D R E S S E E * COPYEE: J/ DOCUMENT 259 SW 00/00/85 AUTHOR BLANK CE ADDRESSEE COPYEE: DOCUMENT 260 \ / 09/00/73 AUTHOR: BURGER EJ JR ADDRESSEE: COPYEE: O CO CO / TYPE PAGES 21/ HUANG A CAMPBELL AD TITLE PAGE 39 CHEMICAL AND TOXICOLOGICAL EVALUATIONS OF ISOLATED SYNTHETIC CHLORO DERIVATIVES OF DIBENZO-P-DIOXIN (NATURE 220, 702-703). FIRESTONE D VERRETT J HEW OTT MG 8' M E D I C A L A N D M O R B I D I T Y S U R V E I L L A N C E F I N D I N G S A M O N G E MPLYEES POTENTIALLY EXPOSED TO TCDD (BRITISH JOURNAL OF INDUSTRIAL MEDICINE AO, 318-32A). BRENNER FE COOK RR 111/ TREATMENT OF THE PORPHYRIAS MECHANISMS OF ACTION (JOURNAL OF INVESTIGATIVE DERMATOLOGY 77, 1 0 7 - 1 1 3 H I N C L U D E S PHOTOCOPY REQUEST FOR JOURNAL ARTICLES). CASE WESTERN RESERVE UNI LAZARTE RA 3y REGULATORY GENE PRODUCT OF THE AH LOCUS; DEMONSTRATION OF THE CYTOSOLIC RECEPTOR IN HUMAN PLACENTA (DEVELOPMENTAL PHARMACOLOGY, 121AH257). EISEN HJ NEBERT DH COOKE P 9 ^ INVESTIGATIONS FOR GENOTOXIC EFFECTS AFTER EXPOSURE TO CRUDE 2, A,5-TRICHL0R0PHEN0L (BRITISH JOURNAL OF INDUSTRIAL MEDICINE AO, 87-91). POTTER AM CITY HOSPITAL NOTTINGHAM SUMMARY; CONFERENCE ON DIBENZODIOXINS AND DIBENZOFURANS, NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SERVICES APRIL 2-3, 1973 (ENVIRONMENTAL HEALTH PERSPECTIVES, 278-282). OFFICE SCIENCE TECHNOLOG CL NUMBER DOCUMENT 261 DATE 00/00/82 AUTHOR ADDRESSEE COPYEE CARAMASCHI F GIAMBELLUCA SE DOCUMENT 262 / 00/00/81 AUTHOR ADDRESSEE COPYEE CANTONI FANELLI L R DOCUMENT AUTHOR ADDRESSEE COPYEE DOCUMENT AUTHOR CALDER CS ADDRESSEE COPYEE DOCUMENT 265 * 00/00/82 AUTHOR COCKERHAM LG ADDRESSEE COPYEE DOCUMENT 266 V 08/20/7A AUTHOR POLAND A ADDRESSEE COPYEE DOCUMENT 267 ^ 00/00/74 AUTHOR LOHS K ADDRESSEE COPYEE O TYPE PAGES MONTESARCHIO E BONETTI F 10^ RIZZARDINI M SALMONA M KOLBYE AC POLLOCK M \/ YOUNG AL 13 BLOVER E 1^ \y 1 TITLE PAGE 40 ANALYSIS OF EXPOSURE TO ENVIRONMENTAL CONTAMINATION BY TCDD IN INDIVIDUALS AFFECTED BY DERMATOLOGICAL LESIONS (LIGIENE MODERNA 77, 681-706). DELCORNO G FAVARETTI C VOLPATO C ISTITUTO IGIENE ITALY INDUCTION OF MIXED FUNCTION OXIDASE BY CHRONIC TREATMENT HITH TCDD IN FEMALE RATS (TOXICOLOGY 21, 159-167). BELVEDERE G CANTONI R ISTITUTO RICERCHE FARMAC APPLIED TOXICOLOGY) DIFFICULTIES IN EXTRAPOLATION OF TOXICITY RESULTS FROM ANIMAL TO MAN (CLIN TOX 15(4), 478). FDA FAILURE OF DIOXIN TO CAUSE POLYNEUROPATHY IN RATS (PROCEEDINGS OF THE UNIVERSITY OF OTAGO MEDICAL SCHOOL 60(2), 26-27). LOVELACE RE PRESBYTERIAN HOSPITAL NY THE ABSENCE OF HEPATIC CELLULAR ANOMALIES IN TCDD EXPOSED BEACH M I C E - A F I E L D S T U D Y ( E N V I R O N M E N T A L T O X I C O L O G Y A N D C H E M I S T R Y 1, 299-308). USAF THE INDUCTION OF ARYL HYDROCARBON HYDROXYLASE BY TCDD) EVIDENCE FOR A RECEPTOR MUTATION IN GENETICALLY NONRESPONSIVE MICE (THE PHARMACOLOGIST, BIOTRANSFORMATION III, 240)(284). UNIV ROCHESTER DIOXIN, A NEW CHEMICAL WARFARE AGENT OF THE IMPERIALISTIC ARMIES (Z MILITAERMED 14(6), 318-319)(BIOCHEM INTERACTIONS 81,1464 07 H I 46 39 3Z). NUMBER DATE DOCUMENT 268 00/00/74 AUTHOR: GREIG JB ADDRESSEE COPYEE: TYPE PAGES 1 TAYLOR DM TITLE PAGE 41 EFFECTS OF TCDD ON STIMULATED DNA SYNTHESIS IN THE LIVER AND KIDNEY OF THE RAT (CHEM BIOLINTERACT 8(1), 31-39X2350). JONES JD MRC LAB DOCUMENT 269 00/00/74 AUTHOR: GRIBBLE GW ADDRESSEE: COPYEE: 1 DARTMOUTH COLLEGE DOCUMENT AUTHOR: ADDRESSEE COPYEE: 270 00/ 00/00 8 DOCUMENT AUTHOR: ADDRESSEE COPYEE: 271 V 00/00/73 GREIG JB MED RES COUNC LAB CARSHA JONES G 2 TCDD DEADLY MOLECULE (CHEMISTRY 47(2), 15-18) (TOXICOLOGY 81,33985 X 3 3 9 5 6 S ) . REFERENCES. TOXIC EFFECTS OF TCDD (FOOD COSMET TOXICOL 1194), 585-595). BUTLER WH BARNES JM DOCUMENT 272 V 00/00/73 AUTHOR: HWANG SW ADDRESSEE COPYEE: 1 EFFECT OF TCDD ON THE BILIARY EXCRETION OF INDOCYANINE GREEN IN RAT ( E N V I R O N H E A L T H P E R S P E C T 5, 227-231). NATL INST ENVIRON HEALTH DOCUMENT 273 00/00/75 AUTHOR ADDRESSEE COPYEE: W O O D S JS' / 1 EFFECTS OF TCDD ON MAMALIAN HEPATIC B-AMINOLEVULINIC ACID S Y N T H E T A S E ( E N V I R O N H E A L T H P E R S P E C T 5, 2 2 1 - 2 2 5 X C H E M I C A L A B S T R A C T 82, 9 6 X 3 9 2 4 5 B ) . NATL INST ENVIRON HEALTH DOCUMENT 274 v 00/00/74 AUTHOR NORRIS LA ADDRESSEE: COPYEE: MILLER RA TOXICITY OF TCDD IN GUPPIES (POECILIA RETICULATUSKBULL ENVIRON CONTAM TOXICOL 12(1), 76-80)(CHEMICAL ABSTRACTS 82, 130)(26753R). PAC NORTHWEST FOREST RAN o U NUMBER DOCUMENT 275 / DATE 07/00/72 TYPE PAGES 2^ AUTHORS ADDRESSEE* COPYEEs BUUHOI NP CENTRE NATIONAL RECHERCH PHAMHUU C DOCUMENT y276 11/00/72 AUTHORS ADDRESSEES COPYEEs </ DOCUMENT 277V 07/00/71 AUTHORS BUUHOI NP ADDRESSEES COPYEEs / HIEN DP 1 DOCUMENT 278 / 11/16/68 AUTHOR ADDRESSEES COPYEEs HIGGINBOTHAM GR RESS J HUANG A CAMPBELL AD A DOCUMENT 279 ^ 00/00/75 A AUTHORS KIMBROUGH RD ADDRESSEES COPYEEs ! DOCUMENT 00/00/82 AUTHORS TIERNAN TO ADDRESSEE COPYEEs LINDER RE \ 1A WRIGHT ST UNIV DOCUMENT AUTHORS ADDRESSEE: COPYEEs 281 ''v- 11/0 A / 8 1 RAMSEY JC G E H R I N G PJ o a* U3 CO Vl HEFNER JG SCHWETZ BA 19 s/ TITLE PAGE ENZYMATIC FUNCTIONS AS TARGETS OF THE TOXICITY OF TCDD (NATURWISSENSCHAFTEN 59(4), 173-174). AZUMGELADE MC SAINTRUF G 42 CHLORODIBENZODIOXINS IN THE LIVER (INFORMATION BULLETIN BIBRA 2(9), 442-443). TETRACHLOROD1BENZODIOXIN - INTIMATIONS OF CARCINOGENICITY? (BIBRA, 295). SAINTRUF G SERVOINSIDOINE J CHEMICAL AND TOXICOLOGICAL EVALUATIONS OF ISOLATED AND SYNTHETIC CHLORO DERIVATIVES OF DIBENZO-P-DIOXIN (NATURE 220, 702-703). FIRESTONE D VERRETT J HEM THE EFFECT OF TECHNICAL AND 99 PERCENT PURE PENTACHLOROPHENOL ON THE RAT LIVER. LIGHT MICROSCOPY AND ULTRASTRUCTURE (ABSTRACTS; FOURTEETH ANNUAL MEETING 23). EPA CHLORODIBENZODIOXINS AND CHLORODIBENZOFURANS; AN OVERVIEH (DET OXICATION OF HAZARDOUS HASTE ANN ARBOR SCI PUB EXNER, JH) THE IN VIVO BIOTRANSFORMATION OF TCDD IN THE RAT (HET K-66681-(38) KARBOHKKI RJ BRAUN HH DON NUMBER / D A T E DOCUMENT 282 ^ 00/00/83 AUTHOR POIGER H ADDRESSEE COPYEE TYPE PAGES 15 SCHLATTER C TITLE PAGE 45 ANIMAL TOXICOLOGY OF CHLORINATED DIBENZO-P-DIOXINS (CHEMOSPHERE 12(4/5), 455-562). SWISS FED INST TECHNOL DOCUMENT 283 AUTHOR ADDRESSEE COPYEE5 06/28/80 3 DIOXIN AND THE HEART (THE LANCET 1(183),1428)(INCLUDES PHOTCOPY REQUEST FOR JOURNAL ARTICLES). DOCUMENT 284 00/00/82 AUTHOR ADDRESSEE COPYEE PUHVEL SM UCLA SCHOOL OF MEDICINE 13 SAKAMOTO M WADSWORTH MEDICAL HAIRLESS MICE AS MODELS FOR CHLORACNElA STUDY OF CUTANEOUS CHANGES INDUCED BY TOPICAL APPLICATION OF ESTABLISHED CHLORACNEGENS (TOXICOLOGY AND APPLIED PHARMACOLOGY 64, 492-503). ERTL DC REISNER RM CENTER DOCUMENT 285 v 00/00/82 AUTHOR' FAVARETTI C MONTESARCHIO E UNIV MILAN ITALY ADDRESSEE COPYEE / 10 DELCORNO G MARNI E MUNICIPAL HEALTH CHLORACNE, CLINICAL SYMPTOMS AND BIOCHEMICAL CHANGES IN EXPOSED TO TCDD IN SEVESO (IGIENE MODERNA 77, 659-674). CARAMASCHI F GIAMBELLUCA SE BONETTI F VOLPATO C DEPT MI CHILDREN DOCUMENT 286 V 00/00/77 AUTHOR BASTOMSKY CH ADDRESSEE COPYEE 8 ENHANCED THYROXINE METABOLISM AND HIGH UPTAKE GOITERS IN RATS AFTER A SINGLE DOSE OF TCDD (ENDOCRINOLOGY 101(1), 292-296)(INCLUDES PHOTOCOPY REQUEST FOR JOURNAL ARTICLES). MCGILL UNIV CL INC QUEBEC DOCUMENT 287 ^ 00/00/81 AUTHOR BALL LM ADDRESSEE COPYEE / CHHABRA RS 13 DOCUMENT 288 V 00/00/78 AUTHOR ALBRO PW CORBETT JT NATL INST OF ENVIRON HEA ADDRESSEE COPYEE Vi o I CO *>>o 21 INTESTINAL ABSORPTION OF NUTRIENTS IN RATS TREATED WITH TCDD (JOU R N A L OF T O X I C O L O G Y A N D E N V I R O N M E N T A L H E A L T H 8, 629-638). NATL INST ENVIRON HEALTH EFFECTS OF TCDD ON LIPID PROFILES IN TISSUE OF THE FISCHER RAT (CHEM BIOL INTERACTIONS 23, 315-330). HARRIS M LAWSON LD NUMBER / DATE DOCUMENT 295 V 00/00/80 AUTHOR RAPPE C ADDRESSEE COPYEE / DOCUMENT 296 V 04/30/81 AUTHOR HAY A ADDRESSEE COPYEE TYPE PAGES 26 UNIV UMEA SHEDEN TITLE PAGE AS CHLOROAROMATIC COMPOUNDS CONTAINING OXYGEN PHENOLS DIPHENYL ETERS, D I B E N Z O - P - D I O X I N S A N D D I B E N Z O F U R A N S ( H A N D B O O K E N V I R O N M E N T A L C H E M 3 157-179). 3 DIOXIN HAZARDS SECRECY AT COALITE (NATURE 290, 729 H I N C L U D E S REQUEST FOR PHOTOCOPY). DOCUMENT 297 V 00/00/83 AUTHOR HARDELL L ADDRESSEE COPYEE 10 EXPOSURE TO POL Y C H L O R I N A T E D DIBENZO-P - D I O X I N S AND DIBENZO-FURANS IN THE ENVIRONMENT (13TH INTL CANCER CONGRESS PART E CANCER MANAGEMENT, 357-369). UNIV HOSPITAL UMEA SWEDE DOCUMENT 2 9 ' 00/00/85 10 AUTHOR ADDRESSEE COPYEE HUDSON LG CHEMICAL INDUSTRY / INST TOSCANO HA JR 0 REGULATION OF EPIDERMAL GROHTH FACTOR BINDING IN A HUMAN KERATINOCYTE CELL LINE BY TCDD (TOXICOLOGY AND APPLIED PHARMACOLOGY 77, 251-259). GREENLEE HF HARVARD UNIV SCHOOL PUBL DOCUMENT 299 W 00/00/85 AUTHOR ADDRESSEE COPYEE BIRNBAUM LS MCKINNEY JD WEBER H NATL INST 12 ENVIRON TOXIC INTERACTION OF SPECIFIC POLYCHLORINATED BIPHENYLS INCREASED INCIDENCE OF CLEFT PALATE IN MICE (TOXICOLOGY PHARMACOLOGY 77,292-302). HARRIS MW LAMB JC IV HEALTH AND AND TCDD) APPLIED DOCUMENT 300 V 02/00/85 AUTHOR ADDRESSEE COPYEE NAGAYAMA J KYUSHU UNIV 7 GENETICALLY MEDIATED INDUCTION OF ARYL HYDROCARBON HYDROXYLASE ACTIVITY IN HUMAN LYMPHOBLASTOID CELLS BY POLYCHLORINATED DIBENZOFURAN ISOMERS AND TCDD (ARCHIVES OF TOXICOLOGY 56(4), 230-235). KIYOHARA C MASUDA Y KURATSUNE M DAIICHI COLLEGE OF PHARM O & NUMBER DATE DOCUMENT 308 00/00/85 AUTHOR: HROBLEWSKI VJ ADDRESSEE* COPYEE: TYPE OLSON JR PAGES 11 DOCUMENT 309 10/00/85 11 AUTHOR: ADDRESSEE COPYEE: LUSTER MI HAYES HT NATL INST HONG LH GREENLEE WF ENVIRON HEALTH CHEMICAL INDUSTRY DOCUMENT 310 l / 00/00/85 5 AUTHOR* ADDRESSEE COPYEE SPILL E / DOCUMENT 311 08/00/85 AUTHOR ADDRESSEE' COPYEE: KELLING CK UNIV HI DOCUMENT 312 v / 00/00/85 AUTHOR JANSING RL ADDRESSEE: COPYEE: DOCUMENT 313 ^ 00/00/85 AUTHOR: CONSTABLE JD ADDRESSEE COPYEE: KNIGHT AS CHRISTIAN BJ SHAIN H HATCH MC O * en TITLE PAGE 47 HEPATIC METABOLISM OF TCDD IN THE RAT AND GUINEA PIG (TOXICOLOGY AND APPLIED PHARMACOLOGY 81, 231-240). SUNY AT BUFFALO SCHOOL 0 ACUTE MYELOTOXIC RESPONSES IN MICE EXPOSED TO TCDD (TOXICOLOGY AND APPLIED PHARMACOLOGY 81(1), 156-165). BOORMAN GA CLARK G DOLD K TUCKER AN INST 0 DIOXINS HAVE LEFT THEIR MARK ON CHILDREN FROM SEVESO NINE YEARS AGO - THE LINGERING (INSIDIOUS) CONTAMINATION. SCIENTISTS (INVESTIGATORS) HAVE NOH DISCOVERED HOH DIOXINS HORK IN THE BODY (STERN MAGAZINE)(TRANSLATION AND ORIGINAL GERMAN DOCUMENT). MCCARTY LP HYPOPHAGIA INDUCED HEIGHT LOSS IN MICE,RATS, AND GUINEA PIGS TREATED HITH TCDD (FUNDAMENTAL AND APPLIED TOXICOLOGY 5(4), 700-712). INHORN SL PETERSON RE ARYL HYDROCARBON HYDROXYLASE INDUCTION IN ADULT RAT HEPATOCYTES IN PRIMARY CULTURE BY SEVERAL CHLORINATED AROMATIC HYDROCARBONS I N C L U D I N G TC D D (FU N D A M E N T A L A N D A P P L I E D T O X I C O L O G Y 5, 713-720). NY ST DEPT HEALTH REPRODUCTIVE EFFECTS OF HERBICIDE EXPOSURE IN VIETNAM; RECENT STUDIES BY THE VIETNAMESE AND OTHERS (TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS 5(4), 231-250). MS GENERAL HOSPITAL COLUMBIA UNIV SCHOOL OF NUMBER DOCUMENT 31A V DATE 07/08/85 AUTHOR: S C H A N T Z SL ADDRESSEE: COPYEE: TYPE PAGES 2 VANVALKENBERG HC TITLE PAGE AS EFFECTS OF PREVIOUS MATERNAL EXPOSURE TO SOCIAL BEHAVIOR OF THERHESUS MONKEY MOTHER INFANT PAIRS (BEHAVIORAL TERATOLOGY SOCIETY NINTH ANNUAL MEETING Bl). BOWMAN RE UNIV HI DOCUMENT 315 ^ 05/00/85 AUTHOR: MCNULTY HP ADDRESSEE: COPYEE: 13 TOXICITY AND FETOTOXICITY OF TCDD, TCDF AND PCB ISOMERS IN RHESUS MACAQUES (MACACA MULATTA) (ENVIRONMENTAL HEALTH PERSPECTIVES 60, 77-88). OR REGIONAL PRIMATE RES DOCUMENT 06/15/85 AUTHOR: GREENLEE WF DOLD KM CHEMICAL INDUSTRY INST 0 ADDRESSEE: COPYEE: / 10 EVIDENCE FOR DIRECT ACTION OF TCDD ON THYMIC EPITHELIUM (TOXICOLOGY AND APPLIED PHARMACOLOGY 79, 112-120). IRONS RD OSBORNE R DOCUMENT 317 V 02/00/85 AUTHOR: ADDRESSEE COPYEE: NAGAYAMA J KURATSUNE M KUROKI KYUSHU H UNIV 5 FUKUOKA GENETICALLY MEDIATED INDUCTION OF ARYL HYDROCARBON HYDROXYLASE ACTIVITY IN MICE BY POLYCHLORINATED DIBENZOFURAN ISOMERS AND TCDD (ARCHIVES OF TOXICOLOGY 56(A), 226-220). MASUDA Y HANDA S JAPA DAIICHI COLLEGE PHARMACE DOCUMENT 318 v 0A/00/85 AUTHOR: ADDRESSEE COPYEE: ROBERTSON LH UNIV MAINZ FED REPUBLIC REGEL U 5 ABSENCE OF LIPID PEROXIDATION AS DETERMINED BY ETHANE EXHALATION IN RATS TREATED HITH TCDD (ARCHIVES OF TOXICOLOGY 57(1), 13-16). FILSER JG OESCH F DOCUMENT 319 00/00/85 AUTHOR: ADDRESSEE: COPYEE: MOORE RH PETERSON RE POTTER CL UNIV WI 1A ANDROGENIC DEFICIENCY IN MALE RATS TREATED HITH TCDD (TOXICOLOGY AND APPLIED PHARMACOLOGY 79, 99-111). THEOBALD HM ROBINSON JA b\b-a DOCUMENT 320 03/15/85 AUTHOR: WALDEN R ADDRESSEE COPYEE: rf* o SCHILLER CM COMPARATIVE TOXICITY OF TCDD IN FOUR (SUB)STRAINS OF ADULT MALE RATS (TOXICOLOGY AND APPLIED PHARMACOLOGY 77(3), A90-A95). NUMBER DATE DOCUMENT 321 03/15/85 AUTHOR OSBORNE R ADDRESSEE COPYEE / DOCUMENT 322 03/00/85 AUTHOR CHAPMAN DE ADDRESSEE COPYEE DOCUMENT 323 00/00/84 AUTHOR ADDRESSEE COPYEE LOVATI MR RESI L UNIV SIENA ITALY DOCUMENT 324V 00/00/85 AUTHOR KERKVLIET NI ADDRESSEE COPYEE DOCUMENT 325 v 00/00/85 AUTHOR HEMMINKI K ADDRESSEE COPYEE DOCUMENT 326 00/00/84 AUTHOR MORTELMANS K ADDRESSEE COPYEE DOCUMENT 327 ^ 00/00/81 AUTHOR* ADDRESSEE COPYEE* REGGIANI O G TYPE PAGES 11 GREENLEE WF 12 SCHILLER CM 8 GALBUSSERA M TANGANELLI P 19 BRAUNER JA VINEIS P 71 ILLEGIBLE 10 9 F HOFFMANN LAROCHE TITLE PAGE 49 TCDD ENHANCES TERMINAL DIFFERENTIATION OF CULTURED HUMAN EPIDERMAL CELLS (TOXICOLOGY AND APPLIED PHARMACOLOGY 77(3), 434-443). CHEMICAL INDUSTRY INST 0 DOSE RELATED EFFECTS OF TCDD IN C57BL/6J AND DBA/2J MICE (TOXICOLOGY AND APPLIED PHARMACOLOGY 78, 147-157). NATL INST OF ENVIRON HEA INCREASED PLASMA AND AORTIC TRIGLYCERIDES IN RABBITS AFTER ACUTE A D M I N I S T R A T I O N OF T C D D ( T O X I C O L O G Y A N D A P P L I E D P H A R M A C O L O G Y 75, 92-97). GRANCESCHINI G WEBER G SIRTORI CR UNIV MILANO ITALY HUMORAL IMMUNOTOXICITY OF POLYCHLORINATED DIPHENYL ETHERS, PHENOXYPHENOLS, DIOXINS AND FURANS PRESENT AS CONTAMINANTS OF TECHNICAL GRADE PENTACHLOROPHENOL (TOXICOLOGY 36,307-324). MATLOCK JP OR ST UNIV EXTRAPOLATION OF THE EVIDENCE ON TERATOGENICITY OF CHEMICALS BETWEEN HUMANS AND EXPERIMENTAL ANIMALS; CHEMICALS OTHER THAN DRUGS ( T E R A T O G E N E S I S C A R C I N O G E N E S I S A N D M U T A G E N E S I S 5(4), 2 5 1 - 3 1 8 ). INST OCCUPATIONAL HEALTH INST ANATOMIA ELSTOLOGIA MUTAGENICITY TESTING OF AGENT ORANGE COMPONENTS AND RELATED CHEMICALS (TOXICOLOGY AND APPLIED PHARMACOLOGY 75, 137-146). MEDICAL SURVEY TECHNIQUES IN THE SEVESO TCDD EXPOSURE (JOUR OF APPLIED TOXICOLOBY 1(6), 323-331). NUMBER DATE DOCUMENT 328 00/00/81 AUTHOR: CORDIE F ADDRESSEE) COPYEE: / DOCUMENT 329 V 03/01/81 TYPE FDA PAGES 1 1 AUTHOR: BOROUJERDI M ADDRESSEE COPYEE: ANDERSON MW DOCUMENT 330 V 00/00/80 AUTHOR: ADDRESSEE: COPYEE: JOHANSSON G G1LLNER M KAROLINSKA INST STOCKHOL 1 DOCUMENT 331 s / 03/00/81 AUTHOR: ADDRESSEE: COPYEE: LUSTER MI GOLDSTEIN JA 1 ALBRO PW NATL INST ENVIRON DOCUMENT 332 V 03/00/81 AUTHOR ADDRESSEE* COPYEE* DOCUMENT OLSON JR SUNY AT BUFFALO / V 333 03/00/81 AUTHOR: ADDRESSEE: COPYEE: GOLDSTEIN 7 JA DO C U M E N T 33< 00/00/82 AUTHOR: TOGNONI G ADDRESSEE: COPYEE: GUDZINOWICZ M KOHLI KK BONACCORSI A TITLE PAGE 50 THE USE OF EPIDEMIOLOGY IN THE REGULATION OF DIOXINS IN THE FOOD SUPPLY (REGUL TOXICOL PHARMACOL 1(3-4), 379-3*7). EFFECT OF TCDD AND BUTYLATED HYDROXYANISOLE (BHA) ON THE ENZYMATIC CONJUGATION OF BENZO(A)PYRENE (BP) METABOLITES (FEDERATION PROCEEDINGS 40(3). LAN F DALHOUSIE UNIV DETECTION OF THE TCDD RECEPTOR IN RAT INTESTINAL MUCOSA USING I S O E L E C T R I C F O C U S I N G IN P O L Y A C R Y A M I D E G E L (D E V B I O C H E M 13, 243-246). HOEGBERG B GUSTAFSSON JA QUANTITATION OF TCDD IN ANIMAL AND HUMAN TISSUES BY RADIO IMMUNOASSAY (THE TOXICOLOGIST 1 ( D ) . CHAE K MCKINNEY JD HEALTH THE IN VITRO AND IN VIVO METABOLISM OF TCDD IN THE RAT (THE TOXICOLOGIST 1(1)). NEAL RA VANDERBILT UNIV EFFECTS OF TCDD ON MICROSOMAL PROSTAGLANDIN SYSTHESIS (THE TOXICOLOGIST 1(D). NATL INST ENVIRON HEALTH EPIDEMIOLOGICAL PROBLEMS HITH TCDD (A CRITICAL V I E W H D R U G METAB REV 13(3), 447-469). IST RIC FARMACOL NUMBER DOCUMENT 335 V DATE 01/00/82 AUTHOR HUDSON LG ADDRESSEE* COPYEE* DOCUMENT 01/00/82 AUTHOR* ROGERS AM ADDRESSEE* COPYEE* DOCUMENT 01/00/82 AUTHOR* RICE RH ADDRESSEE* COPYEE* DOCUMENT 338 V 01/00/82 AUTHOR* POTTER CL ADDRESSEE* COPYEE* DOCUMENT 339 01/00/82 AUTHOR* ADDRESSEE* COPYEE* SEEFELD MD UNIV HI / DOCUMENT 3 A 0 V 01/00/82 AUTHOR* SEEFELD MD UNIV HI ADDRESSEE* COPYEE* / DOCUMENT 3A1 01/00/82 AUTHOR* GASIEHICZ TA ADDRESSEE* COPYEE* y fit oe TYPE PAGES 1 GREENLEE HF ANDERSEN ME 1 GREENLEE HF 1 SIPES IG 1 CORBETT SH 1 CORBETT SH 1 RUCCI G 1 TITLE PAGE 51 INDUCTION OF 7-ETH0XYC0UMARIN O-DEETHYIASE ACTIVITY IN HUMAN EPITHELIAL CELLS IN CULTURE; EVIDENCE FOR DIOXIN RECEPTOR (THE TOXICOLOGIST 2(1)). DENT JG HARVARD SCHOOL PUBLIC HE THE TOXICITY OF TCDD AND PERFLUORODECANOIC ACID IN L5178Y MOUSE LYMPHOMA CELLS (THE TOXICOLOGIST 2 ( D ) . BACK KC WRIGHTPATTERSON AIR FORC EFFECTS OF TCDD ON CULTURED HUMAN EPITHELIAL TARGET CELLS; MODULATION BY HYDROCORTISONE (THE TOXICOLOGIST 2(1)). WHITTENBERGER JL HARVARD SCHOOL PUBLIC HE EFFECTS OF TCDD ON RNA POLYMERASE I INDUCTION IN RAT LIVER (THE TOXICOLOGIST 2(1). RUSSELL DH UNIV AZ COMPARISON OF BODY HEIGHT LOSS AND OXYGEN CONSUMPTION IN RATS TREATED WITH TCDD AND PAIR FED CONTROL RATS (THE TOXICOLOGIST 2(1)). KEESEY RE PETERSON RE EFFECT OF TCDD ON FOOD INTAKE, BODY HIEGHT AND ENERGY EXPENDITURE IN THE RAT (THE TOXICOLOGIST, 2(1)). KEESEY RE PETERSON RE COMPARISON OF THE BINDING PROPERTIES OF CYTOSOLIC RECEPTORS FOR TCDD IN VARIOUS MAMMALIAN SPECIES (THE TOXICOLOGIST 2(1)). UNIV ROCHESTER CLARKSON TH NUMBER DATE DOCUMENT 342 01/00/82 AUTHOR: THEOBALD HM ADDRESSEE: COPYEE' DOCUMENT 343 01/00/82 AUTHOR: ADDRESSEE: COPYEE MUSCARELLA D CORNELL UNIV TYPE PAGES 1 MOORE RM DENNETT D 1 DOCUMENT 3441/ 12/00/82 AUTHOR ADDRESSEE: COPYEE: MCNULTY WP LAY JO JR UNIV NB 3 OR REGIONAL PRIMATE L I P P S T R E U DL DOCUMENT 01/00/82 AUTHOR GASIEHICZ TA ADDRESSEE COPYEE: RUCCI G 1 D O C U M E N T 346 1/ 0 8 / 0 0 / 8 2 AUTHOR ADDRESSEE COPYEE: RAMSEY JC GEHRING PJ HEFNER JG DOM 6 DOCUMENT 347 V / 00/00/82 4 AUTHOR: ADDRESSEE COPYEE: KURL RN KAROLINSKA INST SMEDEN LUND J DOCUMENT 348 V 00/00/82 AUTHOR: KNUTSON JC ADDRESSEE: COPYEE: Vd O POLAND A 10 TITLE PAGE A PROINFLAMMATORY EFFECT OF TCDD ON CARRAGEENAN INDUCED INFLAMMATION IN THE RAT PAH (THE TOXICOLOGIST 2(1)). PETERSON RE UNIV HI MADISON 52 THE EFFECTS OF TCDD ON FETAL DEVELOPMENT IN THE FERRET (THE TOXICOLOGIST 2(1)). BABISH JG NODEN D PERSISTENCE OF TCDD IN MONKEY ADIPOSE TISSUE (FOOD AND CHEMICAL TOXICOLOGY 20(6), 985-986). RES NIELSENSMITH KA OR GRADUATE CENTER K A N G A S NL LYON PA COMPARISON OF THE BINDING PROPERTIES OF CYTOSOLIC RECEPTORS FOR TCDD IN VARIOUS MAMMALIAN SPECIES (THE TOXICOLOGIST 2 ( D ) . CLARKSON TH UNIV ROCHESTER THE IN VIVO BIOTRANSFORMATION OF TCDD IN THE RAT (TOXICOLOGY AND APPLIED PHARMACOLOGY 65(1), 180-189). KARBOHSKI RJ BRAUN HH DIFFERENTIAL EFFECT OF TCDD ON NUCLEAR RNA POLYMERASE ACTIVITY IN THE RAT LIVER AND THYMUS (BIOCHEMICAL PHARMACOLOGY 31(15), 2959-2962). POELLINGER L GUSTAFSSON J RESPONSE OF MURINE EPIDERMIS TO TCDD) INTERACTION OF THE AH AND HR LOCI (CELL 30, 225-239). UNIV HI MADISON NUMBER / DATE TYPE PAGES TITLE PAGE 53 DOCUMENT AUTHOR* ADDRESSEE* COPYEE* DOCUMENT AUTHOR* ADDRESSEE* COPYEE* 349 v 00/00/82 LUND J HUDDINGE UNIV HOSPITAL / 350 V 12/00/82 ROGERS AM / 8 CYTOSOLIC AND NUCLEAR BINDING PROTEINS FOR TCDD IN THE RAT THYMUS (BIOCHEMICA ET BIOPHYSICA ACTA 716, 16-23). KURL RN POELLINGER L GUSTAFSSON J S KAROLINSKA INST SWEDEN ANDERSEN ME 6 MUTAGENICITY OF TCDD AND PERFLUORO-N-DECANOIC ACID IN L5178Y MOUSE LYMPHOMA CELLS (MUTATION RESEARCH 105(6), 445-449). BACK KC AIR FORCE AEROSPACE MEDI DOCUMENT 351^ 00/00/82 AUTHOR* WEBER H ADDRESSEE* COPYEE* 7 ACUTE ORAL TOXICITY OF TCDD METABOLITES IN MALE GUINEA PIGS ( T O XICOLGY LETTERS 14, 117-122). POIGER H SCHLATTER C UNIV OF ZURICH SWITZERLA DOCUMENT 352 ^ 00/00/84 AUTHOR* ADDRESSEE* COPYEE* KOCIBA R / / DOCUMENT 353 V 00/00/78 AUTHOR* ADDRESSEE* COPYEE* SHARMA RP DOW / DOCUMENT 354 4 00/00/82 AUTHOR* ADDRESSEE* COPYEE* KOCIBA RJ / DOCUMENT 355 ^ 00/00/81 AUTHOR* ADDRESSEE* COPYEE* HENCK JM DOW 12 EVALUATION OF THE CARCINOGENIC AND MUT A G E N I C POTENTIAL OF TCDD AND OTHER C HLORINATED DIOXINS (BANBURY REPORT 18* BIOLOGICAL MECHANISMS OF DIOXIN ACTION, 73-81). DOW UT ST UNIV 8 REVERSAL OF IMMUNOLOGIC AND TOXICOLOGIC EFFECTS OF A SINGLE EXPOSURE OF TCDD IN MICE (TRACE SUBSTANCES IN ENVIORN HEALTH XII, 299-306). KOCIBA RJ GEHRING PJ 21 SCHWETZ BA A REVIEW OF THE TOXICITY OF TCDD WITH A COMPARISON TO THE TOXICITY OF OTHER CHLORINATED DIOXIN ISOMERS (ASSOIATION OF FOOD AND DRUG OFFICIALS QUARTERLY BULLETIN 46(3), 168-183). DOW NEW MA 3 TCDDj ACUTE ORAL TOXICITY IN HAMSTERS (TOX AND APPLIED PHARMACOLOGY 59, 405-407). KOCIBA RJ RAO KS 4051 -C. N1 NUMBER DOCUMENT 356 DATE 10/18/84 AUTHOR I KOCIBA RJ ADDRESSEE COrYEE / DOCUMENT AUTHOR ADDRESSEE COPYEE 357 v 00/00/84 SHARMA RP DOW / DOCUMENT AUTHOR: ADDRESSEE COPYEE 358'/ 06/20/80 BUR NATL AFFAIRS DOCUMENT 00/00/79 AUTHOR DIGIOVANNI J ADDRESSEE COPYEE: DOCUMENT AUTHOR: ADDRESSEE COPYEE: 360 V 06/00/80 / DOCUMENT 36 1 V 00/00/80 AUTHOR BICKEL MH ADDRESSEE COPYEE: DOCUMENT 362 / AUTHOR: ADDRESSEE COPYEE 10/24/79 TYPE PAGES 12 CABEY 0 KOCIBA RJ 8 1 BERRY DL 1 1 43 MUEHLEBACH STEFAN 1 TITLE PAGE 54 COMPARATIVE TOXICITY AND BIOLOGIC ACTIVITY OF CHLORINATED DIBENZO-P-DIOXINS AND FURANS RELATIVE TO TCDD (PRESENTED 4TH INTL SYMPOSIUM ON CHLORINATED DIOXINS AND RELATED COMPOUNDS)(PROCEEDINGS IN C H E M O S P H E R E ) . DOW IMMUNOTOXICOLOGIC EFFECTS OF TCDD IN RABBITS. GEHRING PJ UT ST UNIV TCDD (O R A L )(DERMAL)(CURRENT REPORT). TCDD; POTENT ANTICARCINOGENIC ACTIVITY IN CD-I MICE (BIOCHEM BIOPHYS RES COMMUN 86(3), 577-584)(CHEM ABSTRACTS 9 0 U 9 0 180115F). JUCHAU MR UNIV HA SEATTLE TCDD (ORAL)(DERMAL) (NCI BIOASSAY SUMMARY). PHARMACOKINETICS AND ECODISPOSITION OF POLYHALOOENATED HYDROCARBONS; ASPECTS AND CONCEPTS (DRUG METABOLISM REVIEWS 11(2), 149-190) UNIV BERNE SWIZTERLAND DEATHS AMONG TCDD EXPOSED WORKERS FOUND NOT TO EXCEED NATIONAL AVERAGE (PEST AND TOXIC CHEMICAL NEWS, 21). NUMBER / DOCUMENT 363 * DATE 10/00/79 AUTHORS EATON DL ADDRESSEES COPYEEs / DOCUMENT 3 6 4 ^ 00/00/00 AUTHORS ADDRESSEE COPYEEs B E R R Y DL OAK RIDGE NATL 1 LAB DOCUMENT 365 V 03/00/80 AUTHOR: ADDRESSEE! COPYEEs POLI A UNIV MILANO / ITALY DOCUMENT 366 ** 00/00/77 AUTHORS ADDRESSEE! COPYEEs BEATTY PW f DOCUMENT 367 v 02/00/85 AUTHOR NELSON N ADDRESSEE: COPYEEs DOCUMENT 368 ^ 02/00/85 AUTHORS PIVER WT ADDRESSEE: COPYEEs TYPE PAGES 9 KLAASSEN CD TITLE PAGE 55 EFFECTS OF TCDD, KEPONE, AMD POLYBROMINATED BIPHENYLS ON TRANSPORT SYSTEMS IN ISOLATED RAT HEPATOCYTES (TOX AND APPLIED PHARMACOLOGY 51(1), 137-144). UNIV KS MEDICAL CENTER 10 SLAGA TJ UNIV WA STUDIES HITH CHLORINATED D1BENZO-P-DIOXINS, POLYBROMINATED BIPHENYLS, AND POLYCHLORINATED BIPHENYLS IN A TWO STAGE SYSTEM OF MOUSE SKIN TUMORIGENESISj POTENT ANTICARCINOGENIC EFFECTS (ANNALS NEW YORK ACADEMY OF SCIENCES 320, 405-414). DIGIOVANNI J JUCHAU MR 5 FRANCESCHINI G INCREASED TOTAL AND HIGH DENSITY LIPOPROTEIN CHOLESTEROL HITH APOPROTEIN CHANGES RESEMBLING STREPTOZOTOCIN DIABETES IN TETRACHLORODIBENZODIOXIN (TCDD) TREATED RATS (BIOCHEMICAL PHARMACOLOGY 29(5), 835-838). PUGLISI L SIRT0R1 CR 1 VANDERBILT UNIV STUDIES OF THE METABOLISM AND POSSIBLE MECHANISMS OF TOXICITY OF TCDD (CHEMISTRY, BIOLOGICAL 3665-B). NEAL RA 7 PERSPECTIVES ON POLYHALOGENATED AROMATIC COMPOUNDS (ENVIRON HEALTH PERSPECTIVES 59, 179-181). NY UNIV MEDICAL CENTER LINDSTROM FT 1 WASTE DISPOSAL TECHNOLOGIES FOR POLYCHLORINATED BIPHENYLS (ENVIRON HEAL T H PER S P E C T I V E S 59, 163-177). NIEHS OR ST UNIV NUMBER / DATE DOCUMENT 369 \ J 02/00/85 AUTHOR ADDRESSEE: COPYEE: WAKIMOTO T / DOCUMENT 370\/ 02/00/85 AUTHOR: ADDRESSEE COPYEE: TIERNAM TO SOLCH JG HRIGHT ST UNIV TYPE PAGES A TATSUKAWA R TITLE PAGE 56 POLYCHLORINATED DIBENZO-P-DIOXINS AND DIBENZOFURANS IN FLY ASH AND CINDERS COLLECTED FROM SEVERAL MUNICIPAL INCINERATORS IN JAPAN (ENVIRON HEALTH PERSPECTIVES 59, 159-162). EHIME UNIV MATSUYAMA JAP TAYLOR ML HAGEL DJ ST UNIV NY 14 SOURCES AND FATE OF POLYCHLORINATED DIBENZODIOXINS, DIBENZOFURANS AND RELATED COMPOUNDS IN HUMAN ENVIRONMENTS (ENVIRON HEALTH PERSPECTIVES 59, 145-158). GARRETT JH VANNESS GF FERGUSON GL SCHECTER A BINGHAMTON DOCUMENT 371 ^ 02/00/85 AUTHOR: SANO S ADDRESSEE: COPYEE: KAHANISHI S TOXICITY OF POLYCHLORINATED BIPHENYL WITH SPECIAL REFERENCE TO PROPHYRIN M E TABOLISM (ENVIRON HEALTH PERSPECTIVES 59, 137-143). SEKI Y KYOTO UNIV JAPAN DOCUMENT 372 V AUTHOR MIO T ADDRESSEE: COPYEE: 02/00/85 DOCUMENT 373 v 02/00/85 AUTHOR VICKERS AEM ADDRESSEE: COPYEE SUMINO K MECHANISM OF BIOSYNTHESIS OF METHYLSULFONES FROM PCBS AND RELATED COMPOUNDS (ENVIRON HEALTH PERSPECTIVES 59, 129-135). KOBE UNIV JAPAN 8 MECHANISM OF ACTION OF TOXIC HALOGENATED AROMATICS (ENVIRON HEALTH PERS P E C T I V E S 59, 121-128). SLOOP TC LUCIER GW NATL INST OF HEALTH DOCUMENT 374 V 02/00/85 AUTHOR: ADDRESSEE: COPYEE: YOSHIMURA H HA DA I HIROSHIMA UNIV JAPAN y O cm YOSHIHARA S KUROKI J INDUCTIVE EFFECT ON HEPATIC ENZYMES AND TOXICITY OF CONGENERS OF PCBS AND PCDFS (ENVIRON HEALTH PERSPECTIVES 113-119). KOGA N NAGATA K HOKAMA Y KYUSHU UNIV FUKUOKA JAPA NUMBER DATE TYPE PAGES TITLE PAGE 5 DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 375 c / - 02/00/85 NAGAYAMA J KYUSHU UNIV FUKUOKA JAPA 6 KIYOHARA C DAIICHI COLLEGE INDUCING POTENCY OF ARYL HYDROCARBON HYDROXYLASE ACTIVITY IN HUMAN LYMPHOBLASTOID CELLS AND MICE BY POLYCHLORINATED DIBENZOFURAN CONGENERS (ENVIRON HEALTH PERSPECTIVES 59, 107-112). MASUDA Y KURATSUNE M FUKUOKA D O C U M E N T 376 '/ 0 2 / 0 0 / 8 5 AUTHOR: KIMBROUGH RD ADDRESSEE: COPYEE: / 8 LABORATORY AND HUMAN STUDIES ON POLYCHLORINATED BIPHENYLS (PCBS) AND RELATED COMPOUNDS (ENVIRON HEALTH PERSPECTIVES 59, 99-106). US DEPT HEALTH HUMAN SER DOCUMENT 377 V 02/00/85 AUTHOR: ADDRESSEE COPYEE: TAKAMATSU M HIRAYAMA H / DOCUMENT 378 '/ 02/00/85 AUTHOR: HARA I ADDRESSEE: COPYEE: OKI M YOSHIZUKA K 7 SURVEYS OF WORKERS OCCUPATIONALLY EXPOSED TO PCBS AND OF YUSHO PATIENTS (ENVIRON HEALTH PERSPECTIVES 59, 90-97). MAEDA K INOUE Y KURUME UNIV JAPAN 6 HEALTH STATUS AND PCBS IN BLOOD OF WORKERS EXPOSED TO PCBS AND OF THEIR CHILDREN (ENVIRON HEALTH PERSPECTIVES 59, 85-90). KANSAI MEDICAL UNIV OSAK DOCUMENT 02/00/85 AUTHOR: ADDRESSEE: COPYEE: KUNITA N NISHIMURA H OSAKA PREFECTURAL HORI S KASHIMOTO T INST P 6 BIOLOGICAL EFFECT OF PCBS, PCQS AND PCDFS PRESENT IN THE OIL CAUSING YUSHO AND YU-CHENG (ENVIRON HEALTH PERSPECTIVES 59, 79-84). OBANA H OTAKE T IKEGAMI N NATL OSAKA HOSPITAL JAPA DOCUMENT 380 V 02/00/85 AUTHOR: ADDRESSEE: COPYEE: KASHIMOTO T OHI G NATL TAIWAN UNIV MIYATA TUNG T REPUBLI H PCBS, PCOS AND PCDFS IN BLOOD OF YUSHO AND YU-CHENO PATIENTS (ENVIRON HEALTH PERSPECTIVES 59, 73-78). FUKUSHIMA S KUNITA N OSAKA PREFECTURAL INST P UNIV OF TOKYO JAPAN -C. O cn cn NUMBER /- DOCUMENT 381 DATE 02/00/85 TYPE PAGES 6 AUTHOR ADDRESSEE! COPYEE: MIYATA H OSAKA PREFECTURAL INST P FUKUSHIMA S TITLE PAGE 58 PCBS, Pegs AND PCDFS IN TISSUES OF YUSHO AND YU-CHENG PATIENTS (ENVIRON HEALTH PERSPECTIVES 59, 67-72). KASHIMOTO T KUNITA N DOCUMENT AUTHOR ADDRESSEE: COPYEE! 382 v 02/00/85 CHEN PH NATL YANG MING MEDICAL / HONG C C VETERANS 7 GENERAL POLYCHLORINATED BIPHENYLS, DIBENZOFURANS AND QUATERPHENYLS IN TOXIC RICE BRAN OIL AND IN THE BLOOD AND TISSUES OF PATIENTS HITH PCB P O I S O N I N G (Y U - C H E N G ) IN T A I N A N ( E N V I R O N H E A L T H P E R S P E C T I V E S 59, 59-65). RAPPE C NYGREN M HOSPITA UNIV UMEA SNEDEN DOCUMENT 3 8 3 v 02/00/85 AUTHOR: ADDRESSEE! COPYEE! MASUDA Y DAIICHI COLLEGE JAPAN 6 PCB AND PCDF CONGENERS IN THE BLOOD AND TISSUES OF YUSHO AND YU-CHENG PATIENTS (ENVIRON HEALTH PERSPECTIVES 59, 53-58). KUROKI H HARAGUCHI K NAGAYAMA J KYUSHU UNIV FUKUOKA JAPA DOCUMENT 386 02/00/85 AUTHOR: ADDRESSEE: COPYEE: YOSHIMURA ( T DOCUMENT 385 ^ 02/00/85 AUTHOR* ADDRESSEE! COPYEE: DOCUMENT YAMASHITA F / / J 386 ^ 02/00/85 AUTHOR: ADDRESSEE: COPYEE: NAKANISHI Y KANEGAE H 5 HAYABUCHI H RELATIONSHIP BETWEEN THE AMOUNT OF RICE OIL INGESTED BY PATIENTS WITH YUSHO AND THEIR SUBJECTIVE SYMPTOMS (ENVIRON HEALTH PER SPEC T I V E S 59, 67-51). KYUSHU UNIV FUKUOKA JAPA HAYASHI M 5 FETA PCB SYNDROMEi CLINICAL FEATURES, INTRAUTERINE GROWTH RETARDATION AND POSSIBLE ALTERATION IN CALCIUM METABOLIM (ENVIRON HEALTH PERSPECTIVES 59, 61-65). KURUME UNIV KURUME CITY SHIGEMATSU N ISHIMARU S RESPIRATORY INVOLVEMENT AND IMMUNE STATUS IN YUSHO PATIENTS (ENVIRON HEALTH PERSPECTIVES 59, 31-36). KURITA Y MATSUBA K KAWAZOE Y KYUSHU UNIV FUKUOKA JAPA 1o ss c n CD NUMBER , DATE DOCUMENT 387' 02/00/85 AUTHOR: HU Y ADDRESSEE! COPYEE: TYPE PAGES TITLE PAGE 59 131 CLINICAL FINDINGS AND IMMUNOLOGICAL ABNORMALITIES IN YU-CHENG PATIENTS (ENVIRON HEALTH PERSPECTIVES 59, 17-29). NATL TAIWAN UNIV TAIPEI DOCUMENT 388 v/ 02/00/85 AUTHOR! URABE H ADDRESSEE! COPYEE: ASAHI M 5 ' PAST AND CURRENT DERMATOLOGICAL STATUS OF YUSHO PATIENTS (ENVIRON HEALTH PERSPECTIVES 59, 11-15). KYUSHU UNIV FUKUOKA JAPA DOCUMENT 389 v 02/00/85 AUTHOR: ADDRESSEE COPYEE: HSU HSU S NH MA C YEH C 6 DISCOVERY AND EPIDEMIOLOGY OF PCB POISONING IN TAIWAN; A FOUR YEAR FOLLOWUP (ENVIRON HEALTH PERSPECTIVES 59, 5-10). HSU SK WU S WU S DEPT HEALTH REPUBLIC OF DOCUMENT 390V 02/00/85 AUTHOR: NATL INST ENVIRON HEALTH ADDRESSEE! COPYEE: / 179 JAPAN - U.S. JOINT SEMINAR ON TOXICITY OF CHLORINATED BIPHENYLS, DIBENZOFURANS, DIBENZODIOXINS, AND RELATED COMPOUNDS APRIL 25-28, 1983 (ENVIRON HEALTH PERSPECTIVES 59). DOCUMENT AUTHOR: ADDRESSEE COPYEE: 391 00/00/00 / REFERENCES. DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 392 sy 1 2 / 0 0 / 8 4 SCHRIEBER R . 9' THE CLEAN UP BEGINS (BULL ENVIRON CONTAM TOXICOL 33(6), 725-734). MI DEPT NATURAL RESOURCE DOCUMENT 393 V/ 12/00/84 AUTHOR: MONTELEONE P ADDRESSEE: COPYEE: Io or Ur Uj 16 ^ ST LOUIS UNIV SEARCHING FOR GENETIC EFFECTS OF TOXIC CHEMICALS; CHROMOSOMAL ABERRATION AND SISTER CHROMATID EXCHANGE (BULL ENVIRON CONTAM TOXICOL 33(6), 710-725). NUMBER .DATE DOCUMENT 394 12/00/84 AUTHOR: YOUNG AL ADDRESSEE' COPYEE: D O CUMENT 395 N/ 1 2 / 0 0 / 8 4 AUTHOR: SEILIKOFF IJ ADDRESSEE COPYEE: DOCUMENT 396 00/00/84 AUTHOR: KNUTSEN AP ADDRESSEE COPYEE: y DOCUMENT 397 V 12/00/84 AUTHOR: WEBB KB ADDRESSEE: COPYEE: DOCUMENT 398 V 12/00/84 AUTHOR: REKO K ADDRESSEE: COPYEE: DOCUMENT 399 V / 12/00/84 AUTHOR: POWELL RL ADDRESSEE: COPYEE: DOCUMENT 400 ^ 12/00/84 AUTHOR* AYRES SM ADDRESSEE: COPYEE: DOCUMENT 401 12/00/84 AUTHOR: WEBB KB ADDRESSEE' COPYEE: -e. O cn CO TYPE USAF PAGES 8 TITLE PAGE 60 DETERMINATION AND MEASUREMENT OF HUMAN EXPOSURE TO THE DIBENZO-P-DIOXINS (BULL ENVIRON CONTAM TOXICOL 33(6), 702-709). 20 LESSONS FOR LIVING IN A CHEMICAL WORLD (BULL ENVIRON CONTAM TOXICOL 33(6), 682-695). MOUNT SINAI SCHOOL OF ME 9 ST LOUIS UNIV IMMUNOLOGIC EFFECTS OF TCDD EXPOSURE IN HUMANS (BULL ENVIRON CONTAM TOXICOL 33(6), 673-681). 11 ST LOUIS UNIV THE PILOT MISSOURI HEALTH EFFECT STUDY (BULL ENVIRON CONTAM TOXICOL 33(6), 662-672). 7 THE PSYCHOSOCIAL IMPACT OF ENVIRONMENTAL DISASTERS (BULL ENVIRON CONTAM TOXICOL 33(6), 655-661). ECUMENICAL DIOXIN RESPON 7 UNIV CA DAVIS DIOXIN IN MISSOURI; 1971-1983 (BULL ENVIRON CONTAM TOXICOL 33(6), 648-654). 17 ST LOUIS UNIV THE PROSPECTS FOR CHEMICAL DARWINISM (BULL ENVIRON CONTAM TOXICOL 33(6), 631-635). 120 DIOXIN; LESSONS FROM THE MISSOURI EXPERIENCE (ENVIRON C ONTAMINATION AND TOX 33(6)). NUMBER DATE DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 9021/ 00/00/89 FRIEDMAN JM DOCUMENT 903 00/00/89 AUTHOR: GIERTHY JF ADDRESSEE COPYEE- DOCUMENT 909 00/00/89 AUTHOR: ADDRESSEE COPYEE: GREIG SMITH JB AG DOCUMENT 905 00/00/89 AUTHOR: ADDRESSEE: COPYEE: lOVATI MR RESI L UNIV SIENA ITALY DOCUMENT 00/00/82 AUTHOR: VOS JG ADDRESSEE: COPYEE: / DOCUMENT 907 00/00/89 AUTHOR: ADDRESSEE: COPYEE: SEEFELD MD UNIV HI DOCUMENT 908 V 00/00/89 AUTHOR: PUHVEL SM ADDRESSEE: COPYEE: <0 O -C. cn Y\ C O TYPE UNIV TX PAGES 29 CRANE D 8 9 FRANCIS JE MEDICAL RES COUNCIL 7 GALBUSSERA M TANGANELLI P 11 VANLEEUHEN FXR CORBETT SH 12 ERTL DC 6 TITLE PAGE 61 DOES AGENT ORANGE CAUSE BIRH DEFECTS? (TERATOLOGY 29, 193-221). REVERSIBLE INHIBITION OF INVITRO EPITHELIAL CELL PROLIFERATION OF TCDD (TOX AND APPLIED PHARMACOLOGY 74, 91-98). NY ST DEPT HEALTH INCOMPLETE CORRELATION OF TCDD HEPATOTOXICITY HITH AH PHENOTYPE IN MICE (TOX AND APPLIED PHARMACOLOGY 74, 17-25). KAY SJE LOVELL DP LABS INCREASED PLASMA AND AORTIC TRIGLYCERIDES IN RABBITS AFTER ACUTE ADMINISTRATION OF TCDD (TOX AND APPLIED PHARMACOLOGY 75, 91-97). FRANCESCHINI G WEBER G SIRTORI CR UNIV MILANO ITALY ACNEGENIC ACTIVITY OF 3-METHYLCHOLANTHRENE AND BENZOiA)PYRENE AND A COMPARATIVE STUDY HITH TCDD IN THE RABBIT AND HAIRLESS MOUSE (TOXICOLOGY 23, 187-196). DEJONG P NATL INST PUBLIC HEALTH CHARACTERIZATION OF THE HASTING SYNDROME IN RATS TREATED HITH TCDD (TOX AND APPLIED PHARMACOLOGY 73, 311-322). KEESEY RE PETERSON RE INCREASED EPIDERMAL TRANSGLUTAMINASE ACTIVITY FOLLOHING TCDD; VIVO AND IN VITRO STUDIES WITH MOUSE SKIN (TOX AND APPLIED PHARMACOLOGY 73, 42-47). LYNBERG CA UNIV CA LOS ANGELES IN AN U M B E R ATE D O C U M E N T 409 v r :0:0 / 0 0 / 8 0 TYPE PAGES 16 AUTHOR POCCHIARI F VIVIANO G ADDRESSEE COPYEE ^ ISTITUTO SUPERIORE ZAPPONI G DOCUMENT 410 00/00/81 AUTHOR JONES KG ADDRESSEE COPYEE COLE FM 15 DOCUMENT 411 ^ 00/00/79 AUTHOR NIENSTEDT U ADDRESSEE COPYEE PARKKI M 5 DOCUMENT AUTHOR ADDRESSEE COPYEE 412 DOM 04/00/84 77 DOCUMENT AUTHOR: ADDRESSEE COPYEE 413 V 01/23/84 NATL INST OCCUPATIONAL , MILLAR JD 21 DOCUMENT 414 00/00/84 17 AUTHOR: ADDRESSEE COPYEE: HASEMAN JK BOORMAN GA . DOCUMENT 415 00/00/75 CRAWFORD DD MCCONNELL EE 9 AUTHOR SAINTRUF G ADDRESSEE: COPYEE: 6^ Q> HIEN DP TITLE PAGE 62 ACCI D E N TA L R E L E A S E OF T C D D AT SEV E S O I TAL Y 1. S EN S I T I V I T Y AND SPECIFICITY OF ANALYTICAL PROCEDURES ADOPTED TO TCDD ASSAY (INCLUDES FORWARD TO PAPER I-VIHECOTOXICOLOGY AND ENVIRON SAFETY A, 282-297). DI SA DOMENICO AD SILANO V THE ROLE OF IRON IN THE TOXICITY OF TCDD CTOX AND APPLIED PHARMACOLOGY 61, 74-88). SWEENEY GD MCMASTER UNIV ONTARIO EFFECT OF TCDD ON THE HEPATIC METABOLISM OF TESTOSTERONE IN T RAT (TOXICOLOGY 13, 233-236). ILLEGIBLE HE DIOXIN, AGENT ORANGE AND HUMAN HEALTH. TCDD - DIOXIN (CURRENT INTELLIGENCE BULLETIN AO). RESULTS FROM 86 TWO YEAR CARCINOGENICITY STUDIES CONDUCTED BY THE N A T IONAL T O X I C O L O G Y P R O G R A M ( JOUR OF T O X A N D E N V I R O N H E A L T H 14, 621-639). NATL INST ENVIRON HEALTH HUFF JE SIMILARITIES OF THE BIOCHEMICAL EFFECTS OF 2,3,7,8,-TETRACHLORO DlBENZO-P-DIOXINE AND 2,3,7,8,-TETRABROMO DIBENZO-P-DIOXINE IN RATS (COMPTES RENDUS HEBDOMADAIRES DE LACADEMIE DES SCIENCES )PARIS) S E R I E S D, S C E I N C E S N A T U R E L L E S 280, 2 7 0 9 - 2 7 1 1 ) ( O R I G I N A L F RENCH ARTICLE AND TRANSLATION). SUNLONE INC NUMBER DATE DOCUMENT 'Z<416 00/00/75 AUTHOR GREEN S ADDRESSEE COPYEE DOCUMENT 417 \ / t 04/00/73 AUTHOR ADDRESSEE COPYEE DOCUMENT 01/10/77 AUTHOR: MOORE JA ADDRESSEE COPYEE DOCUMENT AUTHOR ADDRESSEE COPYEE: 11/26/80 DOCUMENT 420 00/00/70 AUTHOR FIDELUS J ADDRESSEE COPYEE: / DOCUMENT 421 \ / 00/00/63 AUTHOR: BERKLEY MC ADDRESSEE: COPYEE: DOCUMENT X' 422 \ / 00/00/63 V AUTHOR FLORSHEIM WH ADDRESSEE: COPYCE: TYPE PAGES 1 MORELAND FS 2 1 2 ZIETEK M 2 MAGEE KR 1 VELCOFF SM 1 O OE5 TITLE PAGE 63 CYTOGENETIC EVALUATION OF SEVERAL DIOXINS IN THE RAT (TOX AND A P P L I E D P H A R M A C O L O G Y 33, 161). FDA CHLORODIBENZODIOXINS IN THE LIVER IFOOD AND COSMETIC TOX 11(2), 332-333H2498) . ACNE CHLORINA AND PORPHYRIA CUTANEA TARDA DURING THE MANUFACTURE OF HERBICDES (ROUTING AND TRANSMITTAL SLIP). NATIONAL PARK SERVICE URGED BY AFBF, NFPA, NCA TO CONTINUE 24D USE (PEST & TOXIC CHEM NEWS, 18-19). INDIRECT POLAROGRAPHIC DETERMINATION OF 24D IN BIOLOGICAL MATERIAL ( M I K R O C H I M ACTA 5, 1 0 1 0 - 1 0 1 6 ) ( 7 4 4 1 0 H ) . INST TOX FORENSIC CHEM A NEUROPATHY FOLLOWING EXPOSURE TO A DIMETHYLAMINE SALT OF 24D (ARCH INTERN MED 111(3), 351-3 5 2 K B U L L E T I N OF HYGIENE, 910). SOME EFFECTS OF 24D ON THYROID FUNCTION IN THE RAT; EFFECTS ON PERIPHERAL THY R O X I N E (ENDOCRINOLOGY 72, 3 2 7 ) ( INFORMATION BULLETIN BIBRA 3 FEB 1964, 3 9 H 2 4 D AND THE THYROID 585). WILLIAMS AD NUMBER /DTE ] /D O C U M E N T 423 00/ 00/66 AUTHOR* LONDONO F ADDRESSEE COPYEE: DOCUMENT 424 03/00/68 AUTHOR: PHILLEO HW ADDRESSEE: COPYEE: DOCUMENT 425 ^ 00/00/69 AUTHOR ADDRESSEE* COPYEE: WAY JM / VDOC U M E N T 426 00/00/69 AUTHOR WOLANSKI I ADDRESSEE: COPYEE: DOCUMENT 427 V 01/00/69 AUTHOR: FULLERTON PM ADDRESSEE: COPYEE: s DOCUMENT 428 00/00/70 AUTHOR FIDELUS J ADDRESSEE: COPYEE: DOCUMENT 429 ^ 00/00/60 AUTHOR: APFFEL CA ADDRESSEE: COPYEE: O 05 ro TYPE PAGES DUNSCOMBE WK TITLE PAGE 64 OCCUPATIONAL ACNE 5 CASES CAUSED BY WEEDKILLERS (MEDNA CUTANEA 1(3), 225-231)(ABSTRACTS ON HYGIENE 43(8), 1 0 1 4 H 3 3 4 3 ) . FANG SC EFFECT OF 240 ON INCORPORATION OF 14C INTO URINARY METABOLITES FROM RATS RECEIVING 14C LABELED ACETATE (JOUR AG FOOD CHEM 16(2), 358-360). OR ST UNIV 1 TOXICITY AND HAZARDS TO MAN, DOMESTIC ANIMALS AND WILDLIFE FROM SOME COMMONLY USED AUXIN HERBICIDES (RESIDUE REV 26, 3 7 - 6 2 K P L A N T G ROWTH REGULATORS 71, 2 4 7 M 9 0 1 4 3 S ) . MONKS WOOD EXP STA HUNTI ZAKLAD HISTOL 1 STUDIES OF EFFECT OF ACUTE TOXAEMIA WITH DICHLOROPHENOXYACETIC ACID ON SOME HISTOCHEMICAL REACTIONS OF CELLS IN RAT KIDNEY NE PHRONS (ANN UNIV M CURIE SKLODOWSKA 23, 151-155). EMBRIOL AK MIDDLESEX 4 HOSPITAL TOXIC CHEMICALS AND PERIPHERAL NEUROPATHY1 CLINICAL AND EPIDEMIOLOGICAL FEATURES (PROC RAY SOC MED 62, SECTION OF OCCUPATIONAL MEDICINE WITH SECTION OF NEUROLOGY). LONDO ZIETEK M INDIRECT POLAROGRAPHIC DETERMINATION OF 24D IN BIOLOOICAL MATERIAL ( M 1 K R O C H I M A C T A 5, 1 0 1 0 -1016 M 7 4 4 1 0 H ) . ACAD MED CRACOW POLAND TREGIER A 1 SYNTHETIC AUXINS IN CHEMOTHERAPY OF TRANSPLANTED AND SPONTANEOUS MOUSE ADENOCARCINOMA (IMMUNOLOGY AND EXPERIMENTAL PATHOLOGY 5204HJ NAT CANCER INST 25, 1111-1120). HOMBURGER F BIO-RES CAMBRIDGE MA NUMBER DOCUMENT 430 v IATE 00/00/79 AUTHOR: MEKSASHINA ZA ADDRESSEE* COPYEE: DOCUMENT 431 00/00/71 AUTHOR: BODEN R ADDRESSEE COPYEE: DOCUMENT 432 00/00/79 AUTHOR! KOSCHIER FJ ADDRESSEE' COPYEE: DOCUMENT 433 00/00/70 AUTHOR: LINCER JL ADDRESSEE: COPYEE: \/ DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 434 00/00/70 CRAWFORD IM DOCUMENT 435 00/00/71 AUTHOR: ILLEGIBLE ADDRESSEE: CUPYEE: DOCUMENT 436 ' ' J 00/00/00 AUTHOR: ILLEGIBLE ADDRESSEE: COPYEE1 TYPE PAGES 1 BUSLOVICH sr PREISS D 1 GIRARD PR 1 SOLON JH 1 BLACK WD 1 2 1 o 03 CO TITLE PAGE 65 PECULIAR FEATURES OF THE EMBRYOTOXIC ACTION OF HERBICIDES - D E R I V A T I V E S OF 2 4 D (GI G S A N I T 4, 7 0 - 7 1 ) . ( T O X I C O L O G Y A B S T R A C T S 3 ( 1 ))( 1 6 2 - X 3 ). KOLOSOVSKAYA UM WHITE RUSSIAN SCI RES SA THE DELAY OF RELAXATION OF STIMULATED GUINEA PIG PAPILLARY MUSCLE PRODUCED BY 24D (KLINHSCHR 49(4), 2 27 -2 2 8X 3436). KUHN E UN1V HEIDELBERG TRANSPORT OF 24D BY RAT RENAL CORTICAL SLICES (RENAL PHARMACOLOTY 3732 992) HONG SK ST UNIV NY BUFFALO DDT AND ENDRIN FISH TOXICITY UNDER STATIC VERSUS DYNAMIC BIOASSAY CONDITIONS (AM FISHERIES SOC 99(1), 13-19). NAIR JH SYRACUSE UNIV RES CORP HERBICIDE TOXICITY TO DOMESTIC ANIMALS (PROC S HEED COMF 23). TOXICITY - ILLEGIBLE - APPLICATIONS OF 24D, 245T AND A COTTON DESICCANT TO -ILLEGIBLE (ENVIRONMENTAL POLLUTION). EFFECT OF SPRAYING HITH 24D UPON ABUNDANCE OF POCKET GOPHERS I L L E G I B L E (TOX A N D PHA R M A C O L O G Y , 6 4 8 H 7 1 - 2 5 0 1 ). NUMBER DATE DOCUMENT 437 12/13/83 AUTHOR: KLECKA GM ILLEGIBLE ADDRESSEE COPYEE: DOCUMENT 438 12/13/83 AUTHOR: MENDOZA CG ADDRESSEE: COPYEE y DOCUMENT 439 \ f 04/02/84 AUTHOR: KLECKA GM ADDRESSEE: COPYEE: y/ DOCUMENT 440 \/ 09/19/85 AUTHOR: KLECKA GM ADDRESSEE COPYEE: y DOCUMENT 441 00/00/46 AUTHOR HARRISSON JWE ADDRESSEE COPYEE: / DOCUMENT 442 00/00/46 AUTHOR: KING JE ADDRESSEE: COPYEE // DOCUMENT 443 V 03/14/47 AUTHOR HSUEH YL ADDRESSEE: COPYEE: o cn ON O TYPE PAGES 42 MENDOZA CG DOM ILLEGIBLE 28 19 GONSIOR SJ SHALER TA 43 REES EW 1 1 PENFOUND HT LOU CH TITLE PAGE 66 EFFECT OF BIOAUGMENTATION ON THE REMOVAL OF 24D IN HASTEHATER TREATMENT. GONSIOR SJ MAIER WJ HIGH PERFORMANCE LIQUID CHROMATOGRAPHY DETERMINATION OF 24D IN HASTE TREATMENT EFFLUENTS. DOH SUBSTRATE SPECIFICITY OF A MIXED MICROBIAL CULTURE ISOLATED ON 24D. ILLEGIBLE DOH EFFECT OF DISSOLVED OXYGEN CONCENTRATION OH THE BIODEGRADATION OF 24D . ILLEGIBLE DOH TOXICITY TOHARD CERTAIN SPECIES OF FISH (AMERICAN JOURNAL OF PHARMACY 118, 422-425). EFFECTS OF THO OF THE NEH FORMAGENIC HERBICIDES ON BREAM AND LARGEMOUTH BASS (ECOLOGY 27(4), 372-374)(BI0L0GICAL ABSTRACTS 21, 19017). EFFECTS OF 24D ON SEED GERMINATION AND RESPIRATION (SCIENCE 105(2724), 283-286). TSING HUA UN1V KUNMING C NUMBER ATE DOCUMENT -A 444 v 00/00/70 AUTHOR: LUKOSHKINA LP ADDRESSEE! CDPYEE: TYPE PAGES 1 GUSEINOVA RS DOCUMENT 445 00/ 00/00 AUTHOR: BRITISH IND BIOLOGICAL R ADDRESSEE: COPYEE: 2 DOCUMENT 446 v 00/00/48 4 AUTHOR: RAOUL Y ADDRESSEE: COPYEE: MARNAY C DOCUMENT 447 ^ 04/00/52 AUTHOR: ADDRESSEE COPYEE: ZIMMERMAN PM / DOCUMENT 448 V 04/00/52 11 HITCHCOCK AE 1 AUTHOR: ASSOULY M ADDRESSEE COPYEE: DOCUMENT / 449 x / 11/20/50 5 AUTHOR ASSOULY M ADDRESSEE: COPYEE'- DOCUMENT / / 450 v . 08/26/50 AUTHOR: UNIV OF LONDON ADDRESSEE: ^ COPYEE: ^ O AUDUS LJ 2 TITLE PAGE LIPID PROTEIN CARBOHYDRATE METABOLISM IN HORKER DURING 24D P R O D U C T I O N (TR A Z E R B N A U C H I S S L E D INST T R P R O F Z A B O L 5, 146-? H2995 6 S ) . MELIKZADE TM 67 CONTRASTING STUDIES ON 24D (INFORMATION BULLETIN BIPRA AGRICULTURAL CHEMICALS 8,406). ACTION DE LACIDE IND0L-3-ACCTIQUE ET DE LACIDE 24D SUR LE RAT EN VOIE DE CROISSANCE (COMPTES RENDUS HEBDOMODAITES DES SEANCES DE LACADEMIE DES SCIENCES 226, 1043-1045). JAVILLIER M DETECTION AND DETERMINATION OF 24D AS A CONTAMINANT BY BIOLOGICAL METHODS (BOYCE THOMPSON INST 16(1), 439-449). KIRKPATRICK H JR BOYCE THOMPSON INST FOR SELECTIVE HERBICIDES AND GROHTH SUBSTANCES. PATHOLOGIC EFFECTS ON MAN DURING THE MANUFACTURE OF THE ESTER OF 24D (ARCH MAL PROFESS 12, 2 6 - 3 0 K I N D H Y G I E N E D I G E S T 16(4)). DESHERBANTS SELECTIFS ET SUBSTANCES DE CROISSANCE APERU TECHNIQUE EFFET PATHOLOGIQUE SUR LHOMME AU COURS DE LA FABRICATION (COMMUNICATION A LA SOCICTE DE MEDECINE DU TRAVAIL, 26-30). BIOLOGICAL DETOXICATION OF 24D IN SOILS ISOLATION OF AN EFFECTIVE ORGANISM (NATURE 166, 356). NUMBER DATE DOCUMENT 51 03/00/53 AUTHOR: B A KER DL ADDRESSEE COPYEE: TYPE PAGES 1 RAMSEY FK DOCUMENT AUTHOR ADDRESSEE COPYEE: 52 V/ 11/20/53 LOUSTALOT AJ MORRIS MP FED EXP STATION PUERTO R 2 DOCUMENT 53 03/2/5 AUTHOR: A D D R E S S E E : COPYEE: WELLCOME / FOUNDATION LIMI HASLAM RF DOCUMENT 5 ^ 00/00/59 1 AUTHOR ADDRESSEE COPYEE: SOS J DOW s KERTAI P DOCUMENT 55 00/00/60 1 AUTHOR: S C H I L L I N G E R JI ADDRESSEE' COPYEE: DOCUMENT 56V/ 01/00/62 AUTHOR: DESI I ADDRESSEE: COPYEE: DOCUMENT 57 00/00/62 1 2 AUTHOR: ADDRESSEE: COPYEE: DESI I MARKUS V O 02 02 SOS J TITLE PAGE <8 SUSPECTED POISONING OF DOGS FROM EATING GRASSES TREATED HITK 24D (THE NORTH AMERICAN VETERINARIAN, 194). SYLWE5TER EP IA ST COLLEGE 24D AFFECTS PHOSPHORUS METABOLISM (SCIENCE 118(3037),627-628). GARCIA J PAGAN C ANTI VIRAL COMPOUNDS COMPRISING PHENOXY-PYRIMIDINE DERIVATIVES AND THEIR MANUFACTURE (PATENT SPECIFICATION 706253) EFFECT OF DICHLOROPHENOXYACETIC ACID (DCA) ON THE IODINE 131 UPTAKE OF THE THYROID (ACTA PHYSIOL ACA D SCI HUNGARY 14, 3 6 7 - 3 6 9 H C H E M ABST R ACTS 53, 7433H). MED UNIV BUDAPEST ROHE VK HYGIENIC EVALUATION OF AGRICULTURAL PRODUCTION WITH THE USE OF H E R B I C I D E S (J H Y G EPID E M I O L M I C R O B I O L 8 IM M U N O L P R A G U E 4(2), 2 4 3 - 2 5 2 ) (O C C U P A T IO N A L DISEASES 36(3), 245). NERVOUS SYSTEM EFFECTS OF A CHEMICAL HERBICIDE (ARCH ENVIRONMENTAL H E A L T H 4, 95-102) ( IND U S T R I A L H Y G I E N E D I G E S T A P R I L 1962). HARMFUL EFFECTS ON AGRICULTURAL WORKERS CAUSED BY CHEMICAL WEEDKILLERS (EGESZSEGTUDOMANY BUDAPEST 6(1), 43-51)(OCCUPATIONAL DISEASES 37(7), 713-714). OLASZ J SULE F Wr<r NUMBER DATE DOCUMENT 458 00/00/62 AUTHOR DESI I ADDRESSEE: COPYEE: DOCUMENT 459 07/26/85 AUTHOR: ADDRESSEE COPYEE: MIL RES LAB T A S K E R EJ DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 460 MALL 07/22/85 DOCUMENT 461 08/13/84 AUTHOR: HAZLETON LABS ADDRESSEE: COPYEE: y DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 462 V BEELER 06/00/81 D DOCUMENT 463 ^ 06/25/85 AUTHOR: ADDRESSEE: COPYEE: HAZLETON LABS DUDECK LE , DOCUMENT 464 ^ 00/00/83 AUTHOR: REUBER MD ADDRESSEE: COPYEE: DOCUMENT 465 11/08/71 AUTHOR: IND BIOTEST LABS 0 ADDRESSEE: COPYEE: TYPE SOS J PAGES 1 KOPP S ADAM GP 73 CARREON RE 11 SNYDER FG 32 2 SEROTA DO SERABIAN MA 15 16 CALANDRA JC 24 TITLE PAGE 69 CENTRAL NERVOUS INJURY BY A CHEMICAL HERBICIDE (ACTA MED BUDAPEST 18(9), 929-933) (BULLETIN OF HYGIENE APRIL 1963, 396). A DIETARY THO GENERATION REPRODUCTION STUDY IN FISCHER 399 RATS WITH 29D (FINAL REPORT VOLUME 1 OF 5 H P R 0 J E C T HIL-81137). LEIST PL MERCIECA MD NEMEC MD RODWELL DE MOLTEN 29D) DERMAL SENSITIZATION STUDY IN HARTLEY GUINEA PIGS. RAO KS DOM THE PHARMACOKINETIC EVALUATION OF 19C29D IN THE MOUSE (FINAL REPORT). EISEMAN JL THAKUR AK BAD SCIENCE TELLING IT LIKE IT IS (AGRICHEMICAL AGE, 37E). ONCOGENICITY STUDY IN MICE 29D 52 WEEK PROGRESS REPORT (PROJEC T 2189-101). ALSAKER RD MACHOTKA SV CARCINOGENICITY AND TOXICITY OF 29D (THE SCIENCE OF THE TOTAL ENVIRONMENT 31, 203-218). TERATOGENIC STUDY WITH 29D IN SWISS WEBSTER MICE (REPORT TO THE DOW CHEMICAL COMPANY IBT B8799). NUMBER DOCUMENT 466 DATE 00/00/74 TYPE PAGES 1 AUTHOR SOMERS JD ADDRESSEE COPYEE DOCUMENT 467 00/00/74 AUTHOR CHANG HC ADDRESSEE COPYEE DOCUMENT 468 01/00/74 AUTHOR SOMERS JD ADDRESSEE COPYEE DOCUMENT 469 ^ 00/00/77 AUTHOR ADDRESSEE COPYEE GINIYATUILINA KHABAROVA FY / AK DOCUMENT 470 ^ 00/00/77 AUTHOR ELO H ADDRESSEE COPYEE / DOCUMENT 4 7 1 ^ 10/00/77 AUTHOR ADDRESSEE COPYEE DUX E KISZELY G MORAN ET JR RIP JW 1 7 MORAN ET JR 1 IVANOVA TS YLITALO P 5 4 TOTH I HUNGARIAN ACADEMY OF TITLE PAGE 70 EFFECTS OF EXTERNAL APPLICATION OF PESTICIDES TO THE FERTILE EGG ON H A T C H I N G S U C C E S S A N D E A R L Y C H I C K P E R F O R M A N C E 5. C O N S E Q U E N C E S OF COMBINING 24 D WITH PICLORAM AND EXTREMES IN CONTAMINATION!BULL ENVIRON C O N T A M TOXICOL 11(6), 511-516) (CHEMICAL ABST R A C T S 81, 92)(146595S). REINHART BS UNIV GUELPH ONTARIO EFFECTS OF PHENOXYACETIC ACIDS ON RAT LIVER TISS U E S (J AGR FOOD CHEM 22(1), 62-65)(CHEMICAL ABSTRACTS 80,102)(116880T). CHERRY JH PURDUE UNIV EFFECT OF EXTERNAL APPLICATION OF PESTICIDES TO THE FERTILE EGO ON H A T C H I N G S U C C E S S A N D E A R L Y C H I C K P E R F O R M A N C E 3. C O N S E Q U E N C E S OF COMBINING 24D WITH PICLORAM AND EXTREMES IN CONTAMINATION (BULLETIN OF ENVIRON CONTAMINATION AND TOX 11(1), 511-516). REINHART BS UNIV GUELPH ONTARIO STATE OF THE EYE IN PERSONS IN CONTACT WITH COPPER TRICHLOROPHENOLATE AND INTERMEDIATE PRODUCTS WITH THE SYNTHESIS OF THE HERBICDE 24D (DIASNOSTIKE I LECHENIYU ZABOLEVANII KHIM ETIOL, 59-60). KUDOYAROV RG SYUNYAEVA SI SUBSTANTIAL INCREASE IN THE LEVELS OF CHLOROPHENOXYACETIC ACIDS IN THE CNS OF RATS AS A RESULT OF SEVERE INTOXICATION (ACTA PHARMACOL ET TOXICOL 41,280). UNIV TAMPERE FINLAND THE POSSIBLE CELLULAR MECHANISM OF 2,4-DICHLOROPHENOXYACETATE INDUCED MYOPATHY (FEBS LETTERS 82(2), 219-222). DUX L JOO F SCI MEDICAL UNIV OF SZEGED H NUMBER DATE DOCUMENT 472 ), 00/00/77 AUTHOR) ZAMFIR GH ADDRESSEE) COPYEE: DOCUMENT 473 00/00/78 AUTHOR: KASKEVICH LM^ ADDRESSEE) COPYEE) DOCUMENT 474 00/00/77 AUTHOR: ILLEGIBLE ADDRESSEE) COPYEE* DOCUMENT 475 00/00/78 AUTHOR) SIMON N ADDRESSEE* COPYEE: DOCUMENT 476 00/00/78 AUTHOR: K O S C H I E R FJ ADDRESSEE) COPYEE) DOCUMENT 477 y 00/00/78 AUTHOR) KOSCHER FJ ADDRESSEE) COPYEE: / DOCUMENT V478 00/00/77 AUTHOR: ZETTERBERG G ADDRESSEE) COPYEE) yO fr 05 CD TYPE PAGES 1 IN S T IS S A N A T PUBI 1/ SOBOLEVA LP 7 SINGH PK 1 ILLEGIBLE 1 GIRARD PR 12 GIRARD PR 1 1 UNIV UPPSALA SWEDEN TITLE PAGE PUBLIC HEALTH PROBLEMS CAUSED BY CHEMICALS NITH MUTAGENIC, TERATOGENIC AND CARCINOGENIC EFFECTS (ISIENA 26(3), 203-208). \SI 71 A CASE OF ACUTE POISONING WITH HERBICIDE 24D (HYGIENE OF LABOR AND OCCUPATIONAL DISEASES 10, 2 6 - 3 1 ) (TR A N S L A T I O N A N D ORIGINAL ARTICLE). INST HYGIENE AND TOX OF MUTAGENICITY OF PESTICIDES IN BLUEGREEN ALGAE (MICROBIOL LETT 5(19), 103-107)(79-0681). I NFL U E NC E OF ENVIR ONM ENT AL FA CTORS ON P O R P H Y R I N M E T A B O L I S M (J CHN CHEN CLIN BIOCHEM 16(1), 5 4 H P E S T I C I D E S ABSTRACTS 78-2069). TRANSPORT OF 2,4-DICHL0R0PHEN0XYACETATE BY RAT RENAL CORTICAL SLICESiTOX AND APPLIED PHARMACOLOGY 45, 883-894). HONG SK ST UNIV NY BUFFALO TRANSPORT OF 2,4-DICHL0R0PHEN0XYACETATE BY RAT RENAL CORTICAL SLICES (TOXICOL APPL PHARMACOL 45(3), 883-894MPESTICIDES ABSTRACTS 79-0461). HONG SK ST UNIV NY BUFFALO GENETIC EFFECTS OF PHENOXY ACIDS ON M I C ROORGANISMS (ECOL BULL 27 193-204)(90). NUMBER DATE DOCUMENT 479 ^ 00/ 00/78 TYPE PAGES 1 AUTHOR* ADDRESSEE* COPYEE* KONSTANTINOVA TK SCI RES INST RURAL EFIMENKO LP HYG S TITLE PAGE DATA FOR HYGIENIC STANDARDIZATION OF HERBICIDES 24D IN THE ENVIRONMENT (GIG SANIT 43(11) 9-13). ANTONENKO TA NECHKINA MA 72 DOCUMENT AUTHOR* ADDRESSEE* COPYEE* 480 v / 0 0 / 0 0 / 7 8 ^ KONSTANTINOVA TK SHILOV VN 7 DATA FOR THE HYGIENIC STANDARDIZATION OF 24D HERBICIDES IN ENVIRONMENTAL SUBSTANCES (GIGIENA I S A NITARIIA 11, 9-13). EFIMENKO LP ANTONENKO TA NECHKINA MA RURAL HYGIENE RES INST S DOCUMENT AUTHOR* ADDRESSEE* COPYEE* 481 ^ 00/00/78 KOLNY H KITA K 24D POISONING (MED PR 29C1), 61-63). ETRZNYCH SZPITALA MIEJSK DOCUMENT 482 00/00/78 AUTHOR* GIRIS DA ADDRESSEE* COPYEE* 1 NATURAL RESISTANCE IN CATTLE TO 24D POISONING (VETERINARIYA MOSCOH 9, 93-94). INST EKSP VET MINSK USSR DOCUMENT 483 ^ 00/00/60 AUTHOR* ADDRESSEE* COPYEE* SCHILLINGEN JI / DOCUMENT 484 ' / 10/16/81 AUTHOR* ADDRESSEE* COPYEE* GORZINSKI SJ DITTENBER JA DON DOCUMENT 485 00/ 00/00 AUTHOR* CHANDLER JLR ADDRESSEE* COPYEE* O -CE CD P 1 HYGIENIC EVALUATION OF AGRICULTURAL PRODUCTION WITH THE USE OF H E R B I C I D E S (J H Y G E P I D E M I O L M I C R O B I O L 8 I M M UNOL 4(2) 243-252) (OCCUPATIONAL DISEASES 36(3)). HADE CE KALNINS RV 72 PURIFIED 24D RESULTS OF A 13 MEEK SUBCHRONIC DIETARY TOXICITY STUDY IN THE CDF FISCHER 344 RAT (HET K-002372-(21). MORDEN DC REYES DG SCHUETZ D KOCIBA RJ VOGEL E 3 ILLEGIBLE - OF CYCLAMATE AND SOME PESTICIDES IN DROSOPHILA MELANOGASTER. NUMBER DTE TYPE PAGES DOCUMENT 486 t / 00/00/74 2 AUTHOR : ADDRESSEE COPYEE: KOHL I JL TANDON JS DOCUMENT /487 00/00/83 KHANNA RN SIRCAR KP 9 AUTHOR! KILMODINHEDMAN B HOGLUND S S W E D I S H F A R M E R S S A F E T Y P NATL S W E D I S H LAB F( ADDRESSEE: COPYEE: DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 488 12/19/79 HENCK JW DOW RAO KS 37 DOCUMENT 489 v 00/00/85 AUTHOR: ADDRESSEE: COPYEE: TOYOSHIMA E VA MEDICAL CENTER DOCUMENT 00/00/79 MAYER RF UNI V OF MD 5 8 AUTHOR: ELO HA ADDRESSEE: COPYEE: YLITALO P DOCUMENT \ / 491 01/00/80 AUTHOR: ALEKSASHINA ZA ADDRESSEE: COPYEE: DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 492 10/00/70 SARGENT M o <r> 1 BUSLOVICH SY BLAZEK D 1 TITLE PAGE 73 ABSORPTION AND EXCRETION OF 24D IN MAN 100)(73I07X). ILLEGIBLE DHAR MM IND TOXICOL RES CENTER L (XENOBIOTICA 1(2), 97- STUDIES ON PHENOXY ACID HERBICIDES - FIELD STUDY OCCUPATIONAL EXPOSURE TO PHEN O X Y A C I D H E R B I C I D E S (ARCH TOXICOL 54, 257-265). AKERBLOM M NATL BD OF OCCUPATIONAL )R AG ACNEGENIC POTENTIAL OF 24D SAMPLES(HET K-2372-(25)). JERSEY GC OLSON KJ 24D DOES NOT CAUSE POLYNEUROPATHY IN THE RAT (JOUR OF THE NEUROLOGICAL SCIENCES 70, 225-229). MAX SR ECCLES C DISTRIBUTION OF 2-METHYL-4-CHL0R0PHEN0XYACETIC ACID AND 24D IN MALE RATS; EVIDENCE FOR THE INVOLVEMENT OF THE CENTRAL NERVOUS SYSTEM IN THEIR TOXICITY (TOX AND APPLIED PHARMACOLOGY 51,439-446). UNIV OF TAMPERE FINLAND PECULIAR FEATURES OF THE EMBRYOTOXIC ACTION OF HERBICIDES - DERIVATIVES OF 24D (GIG SANIT 4 7 0 - 7 1 M T O X I C O L O G Y ABSTRACTS 3(1)) (162-X3). KOKOSOVSKAYA UM RES SANIT HYG INST MINSK THE TOXICITY OF 24D AND PICLORAM HERBICIDES TO FISH ILLLEGIBLE PURDUE UNIV NUMBER DATE DOC U M E N T <493 \ / 0 0 / 0 0 / 7 0 AUTHOR i DONAHUE J ADDRESSEE! COPYEE: TYPE PAGES 1 ILLEGIBLE DOC U M E N T 494 \J7 00/ 0 0 / 7 0 AUTHOR: GARRAMAY JL ADDRESSEE! COPYEE: WYE COLLEGE 1 DOCUMENT 495 v 07/17/80 AUTHOR SENCZUK H ADDRESSEE: COPYEE: 8 POGORZELSKA H DOCUMENT 496 5 AUTHOR ADDRESSEE: COPYEE: DE N BUSLOVICH SY SANITATION AND HYGIENE ] DOCUMENT 497 07/17/80 9 AUTHOR: ADDRESSEE: COPYEE: SENCZUK H . LILIENHEIM POGORZELSKA H DOCUMENT 498 AUTHOR: NASH ADDRESSEE: COPYEE: 00/00/82 DOCUMENT 499 ^ 00/00/82 AUTHOR: DRAPER WF ADDRESSEE: COPYEE:^ O PL I M M E R JR 14 STREET JC 18 TITLE PAGE 74 T H E T O X I C I T Y O F C E R T A I N H E R B I C I D E S T O H E N 'S EGG S A S S E S S E D BT THE EGG INJECTION TECHNIQUE (ANN APPL BIOL 66(3), 515-520H71-1415). UNIV OF STTAHTELYDE GLAS BETA OXIDATION OF CERTAIN GROWTH REGULATORS BY PLANT TISSUES (PESTICIDE SCI 1(4), 132-137 H 7 1 - 0 3 6 2 ) . ABSORPTION OF 24D THROUGH THE SKIN (TRANSLATION AND ORIGINAL RUSSIAN ARTICLE). DEBSKA M MEDICAL ACADEMY OF POZNA THE DISTRIBUTION OF HERBICIDES - PHENOXY ACIDS CHLORODERIVATIVES - IN THE BODY OF ALBINO RATS (GIGIENA TRUDA I PROFESSIONALNYYE ZABOLEVANIYA 17(3), 35-37) (TRANSLATION FROM RUSSIAN). VOINOVA IV MILCHINA MG ABSORPTION OF 24D THROUGH THE SKIN (TRANSLATION AND ORIGINAL RUSSIAN ARTICLE) (WARSAW PANSTWOWY ZAKLAD HIGIENY ROCZNIKI 31(6) 611-614). DEBSKA M MEDICAL ACADEMY OF POZNA PESTICIDE RESIDUES AND EXPOSURE - APPLICATORS EXPOSURE TO 24D (ACS SYMPOSIUM SERIES 182, 120-132). A P P L I C A T O R EX PO SUR E TO 24D, DICAMBA, AN D DI CA MB A ISO M ER (J ENVIRON SCI HEALTH B17(4),321-339). UT ST UNIV NUMBER DATE DOCUMENT AUTHORi ADDRESSEE! COPYEE! 500 06/26/82 MILHAM S JR DOCUMENT 501 V 00/00/82 AUTHOR! ADDRESSEE COPYEE: TASKAR PK BROWN HD DOCUMENT 502 V 00/00/82 AUTHOR! ADDRESSEE'COPYEE: / KRTE C / / / DOCUMENT 503 V/ 10/00/82 AUTHOR CUSHMAN JR ADDRESSEE! COPYEE: y DOCUMENT 509 00/00/72 AUTHOR EPSTEIN SS BISHOP Y ADDRESSEE COPYEE: DOCUMENT 505 00/00/82 AUTHOR ADDRESSEE COPYEE: L A V Y TL UNIV AR y / DOCUMENT 506 V 00/00/83 AUTHOR: EASLEY CB UNIV OF NB ADDRESSEE : C O P Y E E : fe. O. oo vO TYPE PAGES TITLE PAGE 1 HERBICIDES, OCCUPATION, AND CANCER (THE LANCET 1(8287)). HA ST DEPT SOCIAL AND HE 75 DAS YT RUTGERS UNIV MEASUREMENT OF 29D AFTER OCCUPATIONAL EXPOSURE (BULL ENVIRON CONTAM T O X 29, 586-591). TROUT JR CHATTOPADHYAY SK 3 29D INDUCED CLASTOGENICITY AND ELEVATED RATES OF SISTER CHROMATID E X C H A N G E S IN C U L T U R E D H U M A N L Y M P H O C Y T E S ( J O U R O F H E R E D I T Y 73, 229-226). JALAL SM ST MARYS COLLEGE UNIV OF ND STREET JC 19 ALLERGIC HYPERSENSITIVITY TO THE HERBICIDE 29D IN BALB/C MICE (JOUR OF TOX AND ENVIORN HEALTH 10(9-5), 729-791). UT ST UNIV 38 DETECTION OF CHEMICAL MUTAGENS BY THE DOMINANT LETHAL ASSAY IN THE MOUSE (TOX AND APPLIED PHARMACOLOGY 23, 288-325). ARNOLD E ANDREA J BASS H CHILDRENS CANCER RES FOU HARVARD MEDICAL SCHOOL HARVARD SCHOOL OF PUBLIC WALSTAD JD OR ST UNIV 7 29D EXPOSURE RECEIVED BY AERIAL APPLICATION CREHS DURING FOREST SPRAY OPERATIONS (JOUR AG FOOD CHEM 30, 375-381). FLYNN RR MATTICE JD 6 LAUGHLIN JM LAUNDERING PROCEDURE FOR REMOVAL OF 29D ACID ESTER AND AMINE H ERBICIDES FROM CONTAMINATED FABRICS (ARCH ENVION CONTAM TOXICOL 71-76). GOLD RE TUPY DR 12, NUMBER TE DOCUMENT 507 10/00/83 AUTHOR: DIERICKX PJ ADDRESSEE! COPYEE! TYPE PAGES TITLE PAGE 76 6 I N T E R A C T I O N OF C H L O R O P H E N O X Y A L K Y L A C I D HERBICIDES W I T H RAT LIVER GLUTATHIONE S-TRANSFERASES (FOOD AND CHEM TOX 21(5), 575-579). INST VOOR HYGIENE EPIDEM DOCUMENT 09/15/83 AUTHOR' ADDRESSEE COPYEE: VAINIO H HIETANEN E UNIV OF TURKU FINLAND LINNAINMAA K MARNIEMI J UNIV HELSINKI 7 HYPOLIPIDEMIA AND PEROXISOME PROLIFERATION INDUCED BY PHENOXYACETIC ACID HERBICIDES IN RATS (BIOCHEMICAL PHARMACOLOGY 32(18), 2775-2800). KAHONEN M NICKELS J PELTONEN P INST OF OCCUPATIONAL HEA FINLAND SOCIAL I N SURANCE INST FI DOCUMENT 00/00/70 AUTHOR! LUKOSHKINA LP ADDRESSEE-- COPYEE: GUSEINOVA RS LIPID PROTEIN CARBOHYDRATE METABOLISM IN WORKERS DURING 24D P R O D U C T I O N ( A ZERB N A U C H I S S L E D INST T R P R O F Z A B O L 5, 146-149). MELIKZADE TM DOCUMENT 510 ^ 00/00/83 AUTHOR: REUBER MD ADDRESSEE: COPYEE: DOCUMENT 511 00/00/83 AUTHOR: OSTERLOH J ADDRESSEE: COPYEE: 16 C A R C I N O G E N I C I T Y A N D T O X I C I T Y OF 2 4D ( S C I E N C E O F THE TOTAL ENVIRON 31, 203-218). LOTTI M 5\ TOXICOLOGIC STUDIES IN A FATAL OVERDOSE OF 24D, MCPP AND C H L O R P Y R I F O S (JOUR O F A N A L Y T I C A L T O X 7, 125-129). POND SM UNIV CA SAN FRANCISCO DOCUMENT 512 00/00/83 AUTHOR: OSTERLOH J ADDRESSEE COPYEE' LOTTI M 1 TOXICOLOGIC STUDIES IN A FATAL OVERDOSE OF 24D,MCPP AND C H L O R P Y R I F O S (J ANAL TOXICAL 7(3), 1 2 5 - 1 2 9 X 9 9 48570G). POND SM UNIV CA SAN FRANCISCO DOCUMENT 513 V ' 00/00/83 AUTHOR: SQUIBB RE ADDRESSEE: COPYEE: ` J 3*-v TILSON HA NEUROBEHAVIORAL ASSESSMENT OF 24D IN RATS (NEUROBEHAVIORAL TOX AND TERATOLOGY 5(3), 331-335). MITCHELL CL NATL INST ENVIRON HEALTH NUMBER DOCUMENT 514 * DATE 00/00/83 TYPE PAGES 11 AUTHOR* LINNAINMAA K ADDRESSEE: C O P Y E E ' /" DOCUMENT 515 00/00/83 AUTHOR: LINNAINMAA K ADDRESSEE COPYEE: DOCUMENT 516 05/00/83 AUTHOR: TORRINGTON KG ADDRESSEE , COPYEE: / INST OF OCCUPATIONAL VAINIO H 2 2 DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 517xi 1 0 / 0 0 / 8 5 KNOPP D MARTIN LUTHER UNIV GERMA NUHN P 7 DOCUMENT 518 \ 00/00/85 AUTHOR: ADDRESSEE: COPYEE: FRANK R CAMPBELL ONTARIO MINISTRY OF NATU RA 9 DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 519 'S 0 0 / 0 0 / 8 4 6 DOCUMENT 520 00/ 00/00 AUTHOR: ILLEGIBLE ADDRESSEE: COPYEE: 1 S O -s - a or TITLE PAGE 77 SISTER CHROMATID EXCHANGES AMONG WORKERS OCCUPATIONALLY EXPOSED TO PHENOXY ACID HERBICIDES 24D AND MCPA (TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS 3, 269-279). HEA SCES AMONG HERBICIDE SPRAYERS EXPOSED TO 24D AND MCPA (MUTATION RESEARCH, 90). INST OCCUPATIONAL HEALTH HERBICIDE EXPOSURE AND PULMONARY DISEASE (JOUR OF OCCUPATIONAL MEDICINE 25(5) ). RADIOIMMUNOASSAY FOR 24D (ARCH TOXICOL 58(1), 27-32). DOBBERKAU HJ RES INST HYGIENE MICROBI FORESTRY WORKERS INVOLVED IN AERIAL APPLICATION OF 24D> EXPOSURE AND URINARY EXCRETION (ARCH ENVIRON CONTAM TOXICOL 19,427-935). SIRONS GJ UNIV OF GUELPH ONTARIO ENVIRONMENTAL HEALTH CRITERIA 29 24D. EFFECT OF 24D ON THE TRANSVERSE TUBULAR SYSTEM OF THE MYOCARDIUM (ILLEGIBLE) (HEALTH ASPECTS OF PESTICIDES 5(6), 288). NUMBER DATE DOCUMENT 521 V 06/00/72 AUTHOR I ILLEGIBLE ADDRESSEE COPYEE: DOCUMENT 522 ^ 00/00/00 AUTHOR: ILLEGIBLE ADDRESSEE! COPYEE: DOCUMENT 523 . /o0o0-/ 00/00 AUTHOR: ILLEOt LE ADDRESSEE: COPYEE: DOCUMENT 524 ^ 00/00/72 AUTHOR: KOPISCHKE ED ADDRESSEE: COPYEE: / DOCUMENT 5 2 5 ^ 0/00/72 AUTHOR: ADDRESSEE: COPYEE: / DOCUMENT 526 00/ 00/00 AUTHOR: BURNDT HO ADDRESSEE: COPYEE: DOCUMENT 527 00/00/00 AUTHOR: ILLEGIBLE ADDRESSEE COPYEE: t/ DOCUMENT 00/00/00 AUTHOR: GEHRING PJ ROWE VK ADDRESSEE: COPYEE: TYPE PAGES 2 TITLE PAGE 78 HERBICIDAL CONTROL OF AQUATIC PLANTS (ILLEGIBLE) (HEALTH ASPECTS OF PESTICIDES 5(6), 268). 1 THE CURRENT STATUS OF PHENOXY HERBICDES - ILLEGIBLE. 2 2AD, ATRAZINE, SHEEP - ILLEGIBLE. 1 THE EFFECT OF 24D AND - ILLEGIBLE - (10357). MN DEPT NATURAL RESOURCE 1 FATAL HUMAN INGESTION OF 24D A COMMON HERBICIDE (ARCH PATHOL 94(3), 270-275). KOSCHER I 2 THE RENAL TRANSPORT OF 24D AND 245T IN VITRO (ABSTRACTS, 441-442). DARTMOUTH MED SCHOOL 1 EFFECTS OF 245T AND OTHER ORGANOHERBICIDES ON THE METABOLISM OF ILLEGIBLE - TESTOSTERONE IN MALE ORGANS OF REPRODUCTION (ABSTRACTS, 441). HV UNIV MEDICAL CENTER KRAMER CG ZIMMER JS THE FATE OF 245T FOLLOWING ORAL ADMINISTRATION TO MAN (ABSTRACTS, 441). ILLLEGIBLE ROSE JQ DOW NUMBER DATE DOCUMENT 52 00/ 00/00 AUTHOR! AL f o t H ADDRESSEE! COPYEE: DOCUMENT 530 00/00/00 AUTHOR: WHITEHEAD CC ADDRESSEE! COPYEE! DOCUMENT 531 AUTHOR: DALLEY ADDRESSEE COPYEE: 00/ 00/00 DOCUMENT 532 ^ 03/00/84 AUTHOR: TOYOSHIMA E ADDRESSEE: COPYEE* DOCUMENT 533 013/00/84 AUTHOR! DOUGHERTY J ADDRESSEE COPYEE: / DOCUMENT 534 V 00/00/84 AUTHOR: LINNAINMAA K ADDRESSEE COPYEE: ^ DOCUMENT 535 V 00/00/75 AUTHOR SENCZUK M ADDRESSEE: COPYEE: DOCUMENT 536 V 00/00/75 AUTHOR: KOHLI JD TAJMLON JS ADDRESSEE: COPYEE: o TYPE PAGES ILLEGIBLE 1 ILLEGIBLE 1 ILLEGIBLE 1 MAYER RF 1 SHULZE G 2 5 INST OF OCCUPATIONAL 1 POGORZELSKA H KHANNA RN SIRCAR KP 3 TITLE PAOE FATAL HUNAN INGESTION OF 240, A CONNON HERBICIDE (ILLEGIBLE). 79 THE EFFECT OF 24D - ILLEGIBLE. FATAL HUNAN INGESTION OF 24D A CONNON HERBICIDE (ILLEGIBLE). DOES 24D CAUSE POLYNEUROPATHY? (NEUROLOGY 34 (SUPPL 1), 145). NAX SR EFFECTS OF 24D ON SCHEDULE CONTROLLED BEHAVIOR (NEUROBEHAVIORAL TOX AND TERATOLOGY 6(2), 177). TAYLOR R UNIV OF KY INDUCTION OF SISTER CHRONATID EXCHANGES BY THE PEROXISONE PROLIFERATORS 24D, MCPA, AND CLOFIBRATE IN VIVO AND IN VITRO (CARCINOGENESIS 5(6), 703-707). HEA THE COURSE OF EXCRETION OF 24D WITH URINE (PRZEBIEG HYDALANIA KHASU 2 4-DHUCHLOROFENOKSYOCTOWEGO Z NOCZENHROCZ PUNSTH ZAKL HIG 26(2), 217-222). INST CHEN ANAL AKAD NED ELININATION OF 24D IN NAN(2874)(FOOD AND COSNETICS TOX 13, 475-476) ABSORPTION AND EXCRETION OF 24D IN NAN (XENOBIOTICA 4, 97 ). GUPTA BN DHAR MN NUMBER ATE DOCUMENT 537 V 0 0 / 00/75 AUTHOR ENIKEEVA NA ADDRESSEE! COPYEE: DOCUMENT 538 V 0 0 / 00/75 AUTHOR! ARKHIPOV GN ADDRESSEE COPYEE: DOCUMENT 539 V 00/00/85 AUTHOR! ZIMMERING S BROWN UNIV ADDRESSEE COPYEE: DOCUMENT 590 - 00/00/77 AUTHOR! ZETTERBERG G RYTTMAN H ADDRESSEE COPYEE-' DOCUMENT y591 00/00/78 AUTHOR ZETTERBERG G ADDRESSEE: COPYEE: y DOCUMENT 592 00/00/73 AUTHOR! YODER J ADDRESSEE COPYEE: / V DOCUMENT 593 00/00/89 AUTHOR: WOODRUFF RC ADDRESSEE: COPYEE: TYPE PAGES ELINA VA KOZLOVA IN MASON JM BUSK L UNIV UPPSALA SWEDEN WATSON M PHILLIPS JP TITLE PAGE 80 INDUSTRIAL HYGIENE AND HEALTH STATUS OF WORKERS PRODUCING THE HERBICIDE AMINE SALT OF 24D (I KHIM PROM-STI, 45-50). DUMKINA GZ MURTAZINA LF CANCEROGENIC PROPERTIES OF THE HERBICIDE AMMONIUM 24D AMINE SALT (VOPR PITAN (5), 83-84). LAB KANTSEROGENOV INST P CHEMICAL MUTAGENESIS TESTING IN DROSOPHILA II, RESULTS OF 20 CODED COMPOUNDS TESTED FOR THE NATIONAL TOXICOLOGY PROGRAM (ENVIRON MUTAGEN 7(1), 87-100). VALENCIA R WOODRUFF RC INFLUENCE OF PH ON THE EFFECTS OF 24D (NA SALT) ON SACCHAROMYCES CEREVISIAE AND SALMONELLA TYPHIMURIUM (MUTAT RES 42, 3-18). ELOVSON R STARECNORDENHAMMAR I MUTAGENICITY OF CHLORINATED PHENOXYACETIC ACIDS IN SACCHAROMYCES CEREVISIAE (MUTAT RES 53(2), 285-286). LYMPHOCYTE CHROMOSOME ANALYSIS OF AGRICULTURAL WORKERS DURING EXTENSIVE OCCUPATIONAL EXPOSURE TO PESTICIDES (MUTAT RES 21, 335-340). BENSON WW PESTICIDE INDUCED COMPLETE AND PARTIAL CHROMOSOME LOSS IN SCREENS WITH REPAIR DEFECTIVE FEMALES OF DROSOPHILA (ENVIRON MUTAGEN 5(6), 835-846). IRWIN D BOWLING GREEN ST UNIV NUMBER p ATE DOCUMENT 544 00/00/58 AUTHOR: WILSON GB ADDRESSEE: COPYEE: TYPE PAGES 1 MORRISON JH D O C U M E N T 545 \ / 0'0 / 0 0 / 8 4 AUTHOR W E IGHTMAN AJ DON RH CENTRE MEDICALE UNIV SWI ADDRESSEE COPYEE: DOCUMENT 546 00/00/80 AUTHOR: ADDRESSEE: COPYEE: WATERS MD VALENCIA R SIMMON VF 1 DOCUMENT AUTHOR: ADDRESSEE: COPYEE' 547 00/00/82 WATERS MD MITCHELL AD GARRETT NE SANDHU SS JORGENSON TA 1 DOCUMENT 548 ^ ^ 0 0 / 0 Q / & l AUTHOR: ADDRESSEE: COPYEE: MATERS MD JORGENSON TA / DOCUMENT 549 00/00/74 AUTHOR: VOGEL E ADDRESSEE: COPYEE' NESNOW S VALENCIA R 1 CHANDLER JLR 1 s h, -a DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 550 vx^ 0 0 ^ 0 0 / 7 8 VACHKOVAPETROVA R le* O <1 CjD 1 MED ACAD BULGARIA TITLE PAGE MITOTIC ACTIVITY AND BEHAVIOR AS AN INDEX OF CHEMICAL EFFECT (NUCLEUS (CALCUTTA) 1, 45-56). 81 THE IDENTIFICATION AND CLONING OF GENES ENCODING HALOAROMATIC CATABOLIC ENZYMES AND THE CONSTRUCTION OF HYBRID PATHWAYS FOR SUBSTRATE MINERALIZATION (BASIC LIFE SCI 28, 47-80). LEHRBACH PR TIMMIS KN OVERVIEW OF SHORT TERM TESTS FOR THE MUTAGENIC AND CARCINOGENIC POTENTIAL OF PESTICIDES (J ENVIRON SCI HEALTH PART B 15, 867-906). MITCHELL AD JORGENSON TA STUDY OF PESTICIDE GENOTOXICITY (BASIC LIFE SCI 21, 275-326). SIMMON VF MORTELMANS KE JONES DC L VALENCIA R PESTICIDES/ MUTAGENIC AND CARCINOGENIC POTENTIAL (ACS SYMP SER 160, 89-113). SIMMON VF MITCHELL AD MUTAGENICITY TESTING OF CYCLAMATE AND SOME PESTICIDES IN DROSOPHILA MELANOGASTER (EXPERIENTIA 30(6), 621-623). MUTAGENIC ACTIVITY OF PESTICIDES (KHIG ZDRAVEOPAZ 21(5), 496-506). NUMBER DATE DOCUMENT 551 00/00/85 AUTHOR TURKULA TE ADDRESSEE COPYEE DOCUMENT 552 00/00/77 AUTHOR TOURE IM ADDRESSEE COPYEE / DOCUMENT 553 ^ 00/00/80 AUTHOR TOMKINS D ADDRESSEE COPYEE DOCUMENT 554 ^ 00/00/81 AUTHOR TIWARI DN ADDRESSEE COPYEE DOCUMENT 555 '/ 00/00/73 AUTHOR STYLES JA ADDRESSEE COPYEE DOCUMENT 556 00/00/82 AUTHOR STRALEY JP ADDRESSEE COPYEE DOCUMENT 557V 00/00/79 AUTHOR SIMMON VF MITCHELL AD ADDRESSEE' COPYEE TYPE PAGES 1 JALAL SM STENZ E 1 KWOK E 1 PANDEY AK 1 1 1 CHRISTIANSEN JA POOLE DC WATERS MD 1 O 00 o TITLE PAGE INCREASED RATES OF SISTER CHROMATID EXCHANGES INDUCED BY THE HERBICIDE 2AD (J HERED 76(3), 213-21A). 82 ACTION OF SELECTED HERBICIDES ON BACTERIOPHAGES AND ESCHERICHIA COLI (ZBL BAKTERIOL PARASIT INFEKTIONSK HTG ABT 2, 132, 163-177). TESTING OF PESTICIDES FOR INDUCTION OF SISTER CHROMATID EXCHANGE IH CHINESE HAMSTER OVARY CELLS (CAN J GENET CYTOL 22, 681). DOUGLAS G 2AD RESISTANT MUTANT STRAINS OF ANACYSTIS NIDULANS AND FILAMENT FORMATION (INDIAN J EXP BIOL 19(10), 988-990). BANARAS HINDU UNIV VARAN CYTOTOXIC EFFECTS OF VARIOUS PESTICIDES IN VIVO AND IN VITRO (MUTAT RES 21(1), 50-51). IMPROVED BIOLOGICAL DEGRADATION OF CHLORINATED HYDROCARBONS USING MUTANT BACTERIA (PROC INT MATER CONF ENG SOC WEST PA A3, 523-532). KOPECKY AL SYBRON BIOCHEM IN VITRO MUTAGENICITY AND GENOTOXICITY ASSAYS OF 38 PESTICIDES (ENVIRON MUTAGENESIS 1, 1A2-1A3). RICCIO ES ROBINSON DE W h\ NUMBER TE DOCUMENT 558 - < A00i /00/79 AUTHOR SIMMON VF ADDRESSEE COPYEE DOCUMENT 559 00/00/77 AUTHOR SIMMON VF ADDRESSEE COPYEE DOCUMENT 560 V / ^ O0O0//00/80 AUTHOR SIMMON VF ADDRESSEE COPYEE DOCUMENT 561 00/00/79 AUTHOR SIEBERT D ADDRESSEE COPYEE DOCUMENT 5 6 2 ^ 00/00/82 AUTHOR SHIRASU Y OHTA T ADDRESSEE COPYEE X 1DOCUMENT 563 00/00/76 AUTHOR SHIRASU Y KADA T ADDRESSEE COPYEE DOCUMENT 569 00/00/75 AUTHOR SHIRASU Y ADDRESSEE COPYEE O 00 TYPE PAGES 1 POOLE DC KAUHANEN K 1 1 SRI INTERNATIONAL LEMPERLE E 1 MORIYA M INOUE T 1 MORIYA M 1 1 TITLE PAGE 83 IN VITRO MICROBIOLOGICAL MUTAGENICITY AND UNSCHEDULED DNA SYNTHESIS STUDIES OF EIGHTEEN PESTICIDES. FINAL REPORT PHASE 2 (EPA-6O0/1-79-04I(PB80-13266)177 PP). MITCHELL AD ROBINSON DE MUTAGENIC ACTIVITY OF CHEMICALS IDENTIFIED IN DRINKING HATER (DEV TOXICOL ENVIRON SCI 2, 2A9-258). TARDIFF RG STANFORD RES INST INT IN VITRO' MICROBIOLOGICAL MUTAGENICITY AND UNSCHEDULED DNA SYNTHESIS STUDIES OF EIGHTEEN PESTICIDES (GOVT REPORTS ANNOUNCEMENTS & INDEX (GRA8I) 10). GENETIC EFFECTS OF HERBICIDES; INDUCTION OF MITOTIC GENE CONVERSION IN SACCHAROMYCES CEREVISIAE (MUTAT RES 22(2), 111-120). MUTAGENICITY SCREENING STUDIES ON PESTICIDES (ENVIRON MUTAGENS CARCINOG PROC INT CONF, 3RD, 331-335). TEZUKA H TERAMOTO S MUTAGENICITY SCREENING OF PESTICIDES IN THE MICROBIAL SYSTEM (MUTAT RES AO, 19-20). KATO K FURUHASHI A SIGNIFICANCE OF MUTAGENICITY TESTING ON PESTICIDES (ENVIRON DUAL SAF A, 226-231). NUMBER DOCUMENT 565 ATE 0ni0/00/79 AUTHOR: SEILER JP ADDRESSEE COPYEE: DOCUMENT 566 00/00/78 AUTHOR: SEILER JP ADDRESSEE COPYEE: DOCUMENT 00/00/70 AUTHOR: SCHROEDER I ADDRESSEE: COPYEE: DOCUMENT 568 00/00/76 AUTHOR: SARMA Y ADDRESSEE: COPYEE: DOCUMENT 5 6 9 ^ 00/00/82 AUTHOR: SANKARANARAYANAN K ADDRESSEE: COPYEE: DOCUMENT 570 v 00/00/80 AUTHOR: ROSENKRANZ HS ADDRESSEE: COPYEE: DOCUMENT 571 v 00/00/78 AUTHOR: RASMUSON B ADDRESSEE: COPYEE: ^3 O - 00 ro TYPE PAGES I 1 SWISS FED RES STN MEYER M 1 TRIPATHI SN 1 1 LEIFER Z 1 SVAHLIN H 1 PHENOXYACIDS AS INHIBITORS OF TESTICULAR DNA SYNTHESIS IN MALE MICE (BULL ENVIRON CONTAM TOXICOL 21, 89-92). THE GENETIC TOXICOLOGY OF PHENOXY ACIDS OTHER THAN 245T (MUTAT RES 55(3-4), 197-226). SWITZE EFFECTS OF THE HERBICIDES 24D, AMINOTRIAZOLE, ATRAZINE, CHLORPROPHAM AND CHLORFURENOL ON NUCLEIC-ACID BIOSYNTHESIS IN THE ASCOMYCETE NEUROSPORA CRASSA (WEED RES 10, 172-177). MUECKE D EFFECTS OF CHEMICALS ON SOME MEMBERS OF INDIAN CHAROPHYTA 2. (CARYOLOGIA 29, 263-276). DETERMINATION AND EVALUATION OF GENETIC RISKS TO HUMANS FROM EXPOSURE TO CHEMICALS, IN CHEMICAL MUTAGENESIS, HUMAN POPULATION MONITORING AND GENETIC RISK ASSESSMENT (PROG MUTAT RES 3, 289-322). DETERMINING THE DNA MODIFYING ACTIVITY OF CHEMICALS USING DNA POLYMERASE DEFICIENT ESCHERICHIA COLI (CHEM MUTAGENSPRIN METHODS THEIR DETECTION 6, 109-147). MUTAGENICITY TESTS OF 24D AND 245T IN GENETICALLY STABLE AND UNSTABLE STRAINS OF DROSOPHILIA MELANOGASTER (ECOL BULL 27, 190-192). UNIV UMEA SWEDEN NUMBER DATE DOCUMENT 572 00/00/83 AUTHOR I RASHID KA ADDRESSEE COPYEE* DOCUMENT 573 00/00/84 AUTHOR RASHID KA ADDRESSEE COPYEE DOCUMENT 00/00/79 AUTHOR RASHID KA ADDRESSEE" COPYEE DOCUMENT 575 ' S 00/00/79 AUTHOR RAMEL C ADDRESSEE COPYEE DOCUMENT 576 00/00/78 AUTHOR RAMEL C ADDRESSEE COPYEE DOCUMENT 577 00/00/81 AUTHOR PROBST GS EPP JK ADDRESSEE COPYEE DOCUMENT 578 v 00/00/79 AUTHOR PROBST GS ADDRESSEE COPYEE .. O o> k jQ TYPE PAGES 1 MUMMA RO BABISH JG 1 PA ST UNIV 1 MAGNUSSON J 1 1 WALLENBERG LAB SWEDE! MCMAHON RE NEAL SB 1 HILL LE 1 TITLE PAGE 85 MUTAGENICITY ASSAYS WITH (2,4-DICHLOROPHENOXY) ACETIC ACID-AMINO ACID CONJUGATES (J AGRIC FOOD CHEM 31(6), 1371-1372). PA ST UN1V POTENTIAL OF 24D CONJUGATES AS PROMUTAGENS IN THE SALMONELLA / MICROSOME MUTAGENICITY TEST (J ENVIRON SCI HEALTH PART B B19(8-9), 689-701). MUMMA RO PA ST UNIV THE RELATIONSHIP BETWEEN MUTAGENIC AND DNA DAMAGING ACTIVITY OF PESTICIDES AND THEIR POTENTIAL FOR CARCINOGENESIS (DISS ABSTR INT B 39(10), 4726). CHEMICAL INDUCTION OF NONDISJUNCTION IN DROSOPHILA (ENVIRON HEALTH PERSPECT 31, 59-66). GENETIC EFFECTS OF PHENOXYACETIC ACIDS IN MAMMALS (ECOL BULL 27, 182-185). CHEMICALLY INDUCED UNSCHEDULED DNA' SYSTHESIS IN PRIMARY RAT HEPATOCYTE CULTURES COMPARISON WITH BACTERIAL MUTAGENICITY USING 218 COMPOUNDS (ENVIRON MUTAGENESIS 3, 11-32). HILL LE THOMPSON CZ CHEMICALLY INDUCED DNA REPAIR SYSTHESIS IN PRIMARY RAT HEPATOCYTES A CORRELATION WITH BACTERIAL MUTAGENICITY (ANNUAL OF THE NY ACADEMY OF SCIENCES 349). NUMBER ATE DOCUMENT 59$ \ S 0o0/ 00/8$ AUTHOR MA TH MOHAMMAD K ADDRESSEE! COPYEE! DOCUMENT 595 00/00/5$ AUTHOR! LOVELESS LE ADDRESSEE! COPYEE! DOCUMENT 596 00/00/83 AUTHOR! LINNAINMAA K ADDRESSEE! COPYEE: DOCUMENT 597 10/00/82 AUTHOR: ADDRESSEE: COPYEE: DOCUMENT LARSEN KO LARSEN JC y 598 00/00/81 AUTHOR: LAMB JC ADDRESSEE: COPYEE: DOCUMENT 599 00/00/81 AUTHOR! LAMB JC MOORE JA ADDRESSEE: COPYEE: DOCUMENT 00/00/80 AUTHOR: KUZMENKO NM PETROVSKAIA OG ADDRESSEE! COPYEE: o O GO TYPE PAGES 1 HARRIS MM BARE JL SPOERL E VAINIO H L.'-' HARDT F LYNGE E MOORE JA 1 MARKS TA 1 y' 1y DIDENKO GG PILINSKIAIA MA I TITLE PAGE 88 TRADESCANTIA MICRONUCLEUS (TRAD-MCN) TEST ON 140 HEALTH RELATED AGENTS (MUTAT RES 138(2-3), 157-167). ANDERSON VA AHMED I LIN G WESTERN IL UNIV SURVEY OF EFFECTS OF CHEMICALS ON DIVISION AND GROHTH OF YEAST AND ESCHERICHIA COLI (J BACTERIOL 68, 637-644). NEISMAN TH SCES AMONG HERBICIDE SPRAYERS EXPOSED TO 24D AND MCPA (MUTAT RES 113, 276-277). CHLOROPHENOLS - PHENOXYCARBOXYLIC ACIDS (ARGEJDSTILSYNET, ARBEJDSMILJ INSTITUTTET ROSENVAENGETS ALLE 16-18). SORUP P KRISTIANSEN E HANSEN T DEVELOPMENT AND VIABILITY OF OFFSPRING OF MALE MICE TREATED HITH CHLORINATED PHENOXY ACIDS AND TCDD (J TOXICOL ENVIRON HEALT H 8, 835-844). MARKS TA HASEMAN JK MALE FERTILITY, SISTER CHROMATID EXCHANGE, AND GERM CELL TOXICITY FOLLOWING EXPOSURE TO MIXTURES OF CHLORINATED PHENOXY ACIDS CONTAINING DIOXIN (J TOXICOL ENVIRON HEALTH 8, 825-834). GLADEN BE ALLEN JH OTDALENNYE POSLEDSTVIIA PRI DEI5TVII PESTITSIDOV (LONG TERM EFFECTS OF PESTICIDES) (GIG SANIT 45(9), 88-89). KURINNYI AI MARTSON LV SHEPILSKAIA NR ALL-UNION RES INST USSR NUMBER DATE -----------------------------------_ _ y -------------------- DOCUMENT 601 U ' 00/00/78 AUTHOR KURINNYI AI ADDRESSEE COPYEE DOCUMENT 602 ' X 00/00/81 AUTHOR KUB1NSKI H ADDRESSEE COPYEE DOCUMENT 603 v/* 00/00/82 AUTHOR; KRTE C ADDRESSEE COPYEE DOCUMENT 604 00/00/79 AUTHOR KRTE C ADDRESSEE COPYEE DOCUMENT 605 00/00/82 AUTHOR KOOL HJ ADDRESSEE COPYEE DOCUMENT 606 */ 00/00/83 AUTHOR KONSTANTINOVA RK ADDRESSEE COPYEE DOCUMENT 607 v 00/00/84 AUTHOR KONSTANTINOVA TK ADDRESSEE COPYEE DOCUMENT AUTHOR ADDRESSEE COPYEE 0 608 v 00/00/82 KHALATKAR AS o 00 or TYPE PAGES 1 . BUTZKE GE l JALAL SM 1 JALAL SM 1 1 VANKREIJL CF SHEVELO FS 1 SHEVELO FS 1 1 BHARGAVA YR TITLE PAGE 89 GENETIC - HYGIENIC REGULATION OF PESTICIDE APPLICATION WITH REGARD FOR THEIR POTENTIAL MUTAGENIC HAZARD (TSITOL GENET 12(4), 353-358). DNA CELL BINDING (DCB) ASSAY FOR SUSPECTED CARCINOGENS AND MUTAGENS (MUTAT RES 89, 95-136). KUBINSKI ZO 24D INDUCED CLASTOGENICITY AND ELEVATED RATES OF SISTER CHROMATID EXCHANGES IN CULTURED HUMAN LYMPHOCYTES (J JERED 73(3), 224-226). ST MARYS COLL 24D INDUCED ALTERATIONS IN MAMMALIAN CHROMOSOMES - PRELIMINARY RESULTS (PROC N D ACAD SCI 33,6). UNIV ND TOXICOLOGY ASSESSMENT OF ORGANIC COMPOUNDS IN DRINKING HATER (CRIT REV ENVIRON CONTROL 12(4), 307-357). ZOETEMAN B CJ MUTAGENIC ACTIVITY OF THE COMBINED EFFECT OF THE HERBICIDES 24D AND 245T (GIG SANIT (4), 21-22). CYTOGENETIC ACTIVITY OF THE COMBINED EFFECT OF THE HERBICIDES 24D AND 245T (GIG SANIT (9), 28-29). SARAT MED INST SARATOV 24D - A NEH ENVIRONMENTAL MUTAGEN (MUTAT RES 103(2), 111-114) NUMBER ^ DATE DOCUMENT 609 V 00/00/71 AUTHOR: KESSLER B ADDRESSEE COPYEE: DOCUMENT 610v/^ 00/00/85 AUTHOR: KALLAK HE ADDRESSEE COPYEE: DOCUMENT 6 1 1 ^ 00/00/76 AUTHOR: JENSSEN D ADDRESSEE COPYEE: DOCUMENT 612 ^ 00/00/80 AUTHOR JENSSEN D ADDRESSEE COPYEE: DOCUMENT 613 ^ 00/00/79 AUTHOR HEINARU A ADDRESSEE: COPYEE: DOCUMENT 614j/ 00/00/73 AUTHOR: HAKEEM H ADDRESSEE COPYEE: DOCUMENT 615 ^ 00/00/75 AUTHOR: HAAG D ADDRESSEE: COPYEE: TYPE PAGES 1 VAPPER MA 1 RENBERG L 1 RAMEL C 1 METSKI R 1 SHEHAB A 1 1 GOERTTLER K TITLE PAGE 90 INTERACTIONS IN VITRO BETHEEN HORMONES AND DMA 3. EFFECTS OF PLANT AND ANIMAL HORMONES ON THE ACTION OF DNA LIGASE AND ITS RELATIONSHIP TO AGE CBIOCHIM BIOPHYS ACTA 290, 330-392). PLANT TISSUE CULTURE AS A MODEL SYSTEM FOR MUTAGENICITY TESTING OF CHEMICALS (MUTAT RES 197(1-2), 51-57). DISTRIBUTION AND CYTOGENETIC TEST OF 29D AND 295T PHENOXYACETIC ACIDS IN MOUSE BLOOD TISSUES (CHEM BIOL INTERACT 19(3-9) 291-299). THE MICRONUCLEUS TEST AS PART OF A SHORT-TERM MUTAGENICITY TEST PROGRAM FOR THE PREDICTION OF CARCINOGENICITY EVALUATED BY 193 AGENTS TESTED (MUTAT RES 75, 191-202). INDUCTION OF RESISTANCE TO COLICINS IN ESCHERICHIA COLI AS A SUITABLE MODEL FOR MUTAGENICITY STUDIES OF CHEMCIAL SUBSTANCES (TARTU RIIKLIKU ULIK TOIM 999, 128-132). CYTOLOGICAL EFFECTS OF SOME HERBICIDES (EGYPT J BOT 16(1/3), 291-301). INFLUENCE OF NONCYTOTOXIC CONCENTRATIONS OF THE HERBICIDE 29D ON THE DNA SYNTHESIS IN CULTURED VERTEBRATE CELLS (ARCH TOXICOL 33, 91-102). PREISS D NUMBER DATE DOCUMENT 616 00/00/81 AUTHOR: GOPALAN HNB ADDRESSEE COPYEE! DOCUMENT AUTHOR! ADDRESSEE COPYEE: 617V^ GOPALAN 00/00/81 HNB DOCUMENT 6 1 8 1 ^ 00/00/79 AUTHOR! GOELTENBOTH F ADDRESSEE' COPYEE DOCUMENT 619*/ 00/00/81 AUTHOR! FISKESJOE G ADDRESSEE: COPYEE! DOCUMENT 620 V/ 00/00/72 AUTHOR: F I C S O R G! ADDRESSEE' COPYEE: DOCUMENT 621 i / ' 00/00/76 AUTHOR! FAHRIG R ADDRESSEE COPYEE' DOCUMENT 622 00/00/86 AUTHOR: POLLAR JR ADDRESSEE' COPYEE- DOCUMENT 00/00/77 AUTHOR: ERCEGOVICH ADDRESSEE' COPYEE: o V 00 Oi < 1 CD TYPE PAGES 1 NJAGI GOE NJAGI GDE 1 1 LASSEN C 1 Nil LO 1 1 1 RASHID RA 1 TITLE PAGE M U T A G E N I C I T Y T E S T I N G O F P E S T I C I D E S 3. D R O S O P H I L A i R E C E S S I V E SEX-LINKED LETHALS (GENETICS 97, S 9 9 ) . 91 MUTAGENICITY TESTING OF PESTICIDES (GENETICS 97(S1),S99). EFFECT OF FOUR HERBICIDE MIXTURES ON THE MITOTIC ACTIVITY OF EICHHORNIA CRASSIPES (261-265). CHLORINATED PHENOXYACETIC ACIDS AND CHLOROPHENOLS IN THE MODIFIED A LLIUM TEST (CHEM BIOL INTERACT 39, 333-399). RENBERG L SURVEY OF PESTICIDES FOR MUTAGENICITY BY THE BACTERIAL-PLATE ASSAY M E T H O D (EMS NEMSL 6, 6-8). PICCOLO GM C O M P A R A T I V E M U T A G E N I C I T Y STUDIES W I T H P E S T I C I D E S CIARC SCI PUBL 10, 161-181). THE EFFECT OF THE PHENOXYACETIC ACID HERBICIDES 295T AND 29D AS ASCERTAINED BY DIRECT EXPERIMENTATION (RESIDUE REV 92, 29-58). MUTAGENESIS INDUCED IN MUTANT STRAINS OF SALMONELLA TYPHIMURIUM BY PESTICIDES (ABSTR PAP AM CHEM SOC 179| PEST 93). NUMBER DATE DOCUMENT 624 V 00/00/72 AUTHOR ADDRESSEE COf'YEE EPSTEIN SS BISHOP Y DOCUMENT / 625 Y 00/00/80 AUTHOR ELZOKA TA ADDRESSEE COPYEE DOCUMENT 626 ^ 00/00/72 AUTHOR EHRENBERG L ADDRESSEE COPYEE DOCUMENT 627 y 00/00/84 AUTHOR DON RH ADDRESSEE COPYEE DOCUMENT 628 ^ AUTHOR DON RH ADDRESSEE COPYEE 00/00/85 DOCUMENT 629 v 00/00/84 AUTHOR DAVRONOV ID ADDRESSEE COPYEE DOCUMENT / 630 v X 00/00/81 AUTHOR B U T C H E R RL ADDRESSEE COPYEE TYPE PAGES 1 ARNOLD E MCKENZIE WH 1 1 1 WEIGHTMAN AJ PEMBERTON JM 1 1 PAGE RD 1 TITLE PAGE 92 DETECTION OF CHEMICAL MUTAGENS BY THE DOMINANT LETHAL ASSAY IN THE MOUSE (TOXICOL APPL PHARMACOL 23, 288-325). ANDREA J BASS H CYTOLOGICAL EFFECTS OF THE HERBICIDES 24D AND 245T ON HUMAN PERIPHERAL LYMPHOCYTES EXPOSED IN VITRO (AM J HUM GENET 32, 154A). ON THE MUTAGENIC ACTION OF PHENOXY ACID PREPARATIONS (NEHSLETT ENVIRON MUTAGEN SOC 6, 27). TRANSPOSON MUTAGENESIS AND CLONING ANALYSIS OF THE PATHWAYS FOR DEGRADATION OF 24D AND 3-CHL0R0BENZ0ATE IN ALCALIGENES EUTROPHUS JMP134(PJP4) (J BACTERIOL 161(1), 85-90). KNACKMUSS HF TIMMIS KN GENETIC AND PHYSICAL MAP OF THE 24D - DEGRADATIVE PLASMID PJP4 (J BACTERIOL 161(1), 466-468). RECOMBINANT - INDUCING EFFECT OF COTTON DEFOLIANTS ON YEAST SACCHAROMYCETES (BIOL NAUKI (MOSCOW (4), 87-90). INTRODUCTORY REMARKS; ENVIRONMENTAL ENDOGENOUS HAZARDS TO THE FEMALE REPRODUCTIVE SYSTEM (ENVIRON HEALTH PERSPECT 38, 35-37). NUMBER DOCUMENT 631 DATE 00/00/82 AUTHOR BULL RJ ADDRESSEE COPYEE DOCUMENT 632 00/00/73 AUTHOR BONGSO RA ADDRESSEE COPYEE DOCUMENT 633 00/00/73 AUTHOR BISHUN NP RAVEN RW ADDRESSEE COPYEE DOCUMENT 634 00/00/73 AUTHOR BERIN EG ADDRESSEE COPYEE DOCUMENT 635 00/00/76 AUTHOR BASRUR SV ADDRESSEE COPYEE DOCUMENT 636 V 00/00/79 AUTHOR BARHAD B MELINTE L ADDRESSEE COPYEE DOCUMENT 637 V 00/00/69 AUTHOR BAMBERGER ES ADDRESSEE COPYEE i O 00 CD TYPE PAGES 1 BASRUR PK 1 HILLIAMS DC PARKE DV 1 1 BUSLOVICH SY FLETCHER RA 1 DINU I 1 1 SHARABANI M TITLE PAGE 93 EXPERIMENTAL METHODS FOR EVALUATING THE HEALTH RISKS ASSOCIATED HITH ORGANIC CHENICALS IN DRINKING HATER (TOXICOL ENVIRON CHEM 6(1), 1-18). IN VITRO RESPONSE OF BOVINE CELLS TO 240 (IH VITRO 8, 416-417). CHROMOSOME DAMAGE INDUCED BY CHEMICALS (CHEM-BIOL INTERACTIONS 6(6), 375-392). MILLS J LLOYD N GENETIC ACTIVITY OF DIETHYLAMINE SALT OF 24D (BENET TSITOL ISSLED YAD TSITOPLAZMATICHESKOI NASLEDSTVENNOSTI, 154-157). PEKARSKAYA LS IN VITRO EFFECTS OF 24D ON BOVINE CELLS (CAN J COMP MED 40, 408-415). BASRUR PK MUTAGENIC / CARCINOGENIC POTENTIAL OF SOME PESTICIDES HITH THE "SALMONELLA - MICROSOME" SYSTEM (REV 10 BACTERIL VIRUSOL PARAZITOL EDIDEMIOL PNEUMOFTIZIOL 10 28(1), 77-83). ROMAN A BOGHIANU L THE EFFECT OF PLANT GROHTH REGULATORS ON DNA (ISR J CHEM 7, 122). NUMBER yBAlE DOCUMENT 638 ' S 00/00/73 AUTHOR-- BALOBANOA MJ KOCSIS F ADDRESSEES COPYEEs DOCUMENT 639 y / ' 00/00/84 AUTHORS AZATYAN RA ADDRESSEE COPYEEs DOCUMENT 640 t / ' 00/00/82 AUTHOR: ANONYMOUS ADDRESSEE COPYEEs DOCUMENT 641 \ / 00/00/78 AUTHOR ANONYMOUS ADDRESSEE COPYEEs DOCUMENT 642 00/00/82 AUTHOR: ANONYMOUS ADDRESSEE COPYEEs DOCUMENT 6431/ 00/00/72 AUTHOR ANDERSEN KJ ADDRESSEE COPYEEs DOCUMENT 644 / 00/00/78 AUTHORS ANDERSON D ADDRESSEE' C0PYEEi rf* O O co o c5 0^ TYPE PAGES 1 ANTONI F AVAKYAN VA 1 1 1 1 KEIGHTY EO 1 STYLES JA 1 TITLE PAGE 94 EFFECT OF 24D OH SEMICONSERVATIVE AND DNA REPAIR SYNTHESIS )CASE REPORT BULLOUS DERMATITIS AFTER EXPOSURE TO 24D) (BER OESTERR STUDIENGES ATOMENERG 2218, 1-7). ALTMANN H VINCZE I CYTOGENETIC ACTIVITY OF 24D AND TREFLAN HERBICIDES ON THE CHROMOSOMES OF CREPIS CAPILLARIS L (BIOL ZH ARM 37(6), 460-463). MIRZOYAN GI MUTAGENESIS TESTING RESULTS (NTP TECH BULL 7, 5-9). CHLORINATED PHENOXY ACIDS AND THEIR DIOXINS; GENETICS - SUMMARY (ECOL BULL 27, 179-181). REVIEW OF LITERATURE ON HERBICIDES , INCLUDING PHENOXY HERBICIDES AND ASSOCIATED DIOXINS VOLUME I. ANALYSIS OF LITERATURE (GOVT REPORTS ANNOUNCEMENTS 8 INDEX (GRA8I) (8)). EVALUATION OF HERBICIDES FOR POSSIBLE MUTAGENIC PROPERTIES (J AGRIC FOOD CHEM 20, 649-656). TAKAHASHI MT AN EVALUATION OF 6 SHORT TERM TESTS FOR DETECTING ORGANIC CHEMICAL CARCINOGENS APPENDIX 2, THE BACTERIAL MUTATION TEST (BR J CANCER 37, 924-930). NUMBER DATE DOCUMENT 645 00/00/84 AUTHOR: AIRAPETYAN RB ADDRESSEE: COPYEE: x/ DOCUMENT 646 00/00/77 AUTHOR: AHMED FE ADDRESSEE: COPYEE: DOCUMENT x/ 647 00/00/76 AUTHOR: AHMED F ADDRESSEE: COPYEE: y DOCUMENT 648 00/00/67 AUTHOR: YANAGISHIMA N ADDRESSEE COPYEE: DOCUMENT 649 x/ 00/00/71 AUTHOR: YAMADA Y ADDRESSEE: COPYEE: DOCUMENT 650 ^ 00/00/73 AUTHOR VASIL IK ADDRESSEE: COPYEE: DOCUMENT 651 00/00/69 AUTHOR: VASIL IK ADDRESSEE: COPYEE: DOCUMENT 652 00/00/76 AUTHOR: TOMKINS DJ ADDRESSEE: CUrYEE: ^ *7<s> O CD TYPE PAGES 1 AVAKYAN VA LEWIS NJ 1 2V SHIMODA C 1 YASUDA T 1 1 ALDRICH HC 1 GRANT WF 1 TITLE PAGE 95 CYTOGENETIC ACTIVITY OF 24D DALAPON AND SEMERON HERBICIDES ON THE CHROMOSOMES OF ALLIUM CEPA L (BIOL ZH ARM 37(5), 404-40). AZATYAN RA PESTICIDE INDUCED OUABAIN RESISTANT MUTANTS IN CHINESE HAMSTER V79 CELLS (CHEM BIOL INTERACT 19(3), 369-374). HART RM ENVIRONMENTAL GENETICS; MODEL TO INVESTIGATE POLLUTANTS PRODUCING GENETIC DAMAGE (DISS ABSTR INT B 36(8), 3737). PRODUCTION OF YEAST VARIANTS BY AUXIN AND EFFECTS OF PLANT GROWTH REGULATORS ON THESE VARIANTS (PLANT CELL PHYSIOL 8(1), 109-119). OSAKA CITY UNIV JAPAN THE INTERRELATIONSHIP OF 24D WITH MOLECULAR COMPONENTS OF THE CELL DURING CALLUS INDUCTION (AGRIC BIOL CHEM 35, 99-104). KOGE M SEKIYA J MORPHOGENETIC, HISTOCHEMICAL AND ULTRASTRUCTURAL EFFECTS OF PLANT GROWTH SUBSTANCES IN VITRO (BIOCHEM PHYSIO PFLANZEN 164, 58-71). BIOLOGY OF CALLUS FORMATION IN "GERMINATING " SEEDS OF SWEET PEA (24D) (ABST XI INT BOT CONGR, 227). MONITORING NATURAL VEGETATION FOR HERBICIDE INDUCED CHROMOSOMAL ABERRATIONS (MUTAT RES 36, 73-84). NUMBER x DATE DOCUMENT 653 'S 00/00/72 AUTHOR: SPANG HA ADDRESSEE COPYEE: DOCUMENT 65A \ S 00/00/71 AUTHOR: SMIRNOV Y ADDRESSEE COPYEE: DOCUMENT 655 00/00/75 AUTHOR: SKORUPSKA H ADDRESSEE: COPYEE: DOCUMENT 656 00/00/76 AUTHOR: SKORUPSKA H ADDRESSEE: COPYEE: DOCUMENT 657 00/00/76 AUTHOR: SINGH BD ADDRESSEE: COPYEE: DOCUMENT 658 00/00/77 AUTHOR: SINGH BD ADDRESSEE: COPYEE: DOCUMENT 659 ^ 00/00/75 AUTHOR: SINGH BD ADDRESSEE: COPYEE: TYPE PLATT RS PAGES 1 FEDOROV AA 1 1 1 SINGH RM 1 1 HARVEY BL 1 TITLE PAGE 96 EFFECT OF PLANT GROWTH SUBSTANCES ON THE HYPERCHROMICITY OF DNA (PHYSIOL PLANT 27, 321-326). TERATISMS IN PLANTS INDUCED BY HIGH DOSES OF GROWTH STIMULATORS AND HERBICIDES. BIOCHEMICAL MECHANISMS OF THE INDUCTION OF THESE TERATISMS (BOT ZH (LENINGRAD) 56, 633-696). SHKOLNIK M RADIOMIMETIC EFFECT OF HERBICIDES ON THE PROGRESS OF MITOSES IN PEA (PISUM SATIVUM) IN COMPARISON WITH THOSE OF CHEMOMUTAGENS AND GAMMA RAYS (GENET POL 16, 301-311). EFFECT OF SOME HERBICIDES, CHEMOMUTAGENS AND GAMMA RADIATION ON MEIOSIS IN PEA (PISUM SATIVUM) (GENET POL 17(2), 199-157). REDUCTION IN ANAPHASE BRIDGE FREQUENCY BY 29D IN IRRADIATED AND NORMAL WHEAT (TRITICUM AESTIVUM L) ROOT TIPS (INDIAN J EXP BIOL 19, 526-527). SINGH RB SINGH Y EFFECTS OF IAA, NAA AND 29D ON CYTOGENETIC BEHAVIOR OF HAPLOPAPPUS GRACILIS (NUTT) GRAY CALLUS CULTURES (CARYOLOGIA 29, 997-955). EFFECTS OF DIFFERENT 29D CONCENTRATIONS ON THE CYTOGENETIC BEHAVIOR OF PLANT CELLS CULTURED IN VITRO (BIOL PLANT 17, 167-179). NUMBER DATE DOCUMENT 660 y 00/00/75 AUTHORt SINGH BD ADDRESSEE COPYEEi DOCUMENT 661^ 00/00/77 AUTHOR SINGH BD SINGH RM ADDRESSEE! COPYEE: DOCUMENT 662 S/^ 00/00/75 AUTHOR: SINGH BD ADDRESSEE: COPYEE: DOCUMENT 663 ^ 00/00/76 AUTHOR: SINGH BD ADDRESSEE! COPYEE: DOCUMENT 664 00/00/76 AUTHOR: SIKKA K ADDRESSEE: COPYEE: DOCUMENT 665 \f 00/00/82 AUTHOR! SIDDIQI SA ADDRESSEE' COPYEE: DOCUMENT 666 \s'' 00/00/48 AUTHOR: RYLAND AO ADDRESSEE: COPYEE: TYPE PAGES 1 HARVEY BL 1 SINGH Y BHATNAGAR PS 1 1 SHARMA AK 1 ANSARI MK 1 1 TITLE PAGE 97 DOES 24D INDUCE MITOTIC IRREGULARITIES IN PLANT TISSUE CULTURES (EXPERIENTIA 31,785-787). CYTOGENETIC EFFECTS OF SEED TREATMENT WITH IAA, NAA AND 24D IN BARLEY HORDEUM VULGARE L (INDIAN J EXP BIOL 15, 1107-1108). SINGH RB SINGH VP COMPARATIVE STUDY OF CYTOGENETIC EFFECTS OF THO CULTURE MEDIA ON SUSPENSIONS OF HAPLOPAPPUS GRACILIS (ACTA BOT INDICA 3, 98-103). COMPARISON OF CYTOGENETIC EFFECTS OF IAA, NAA AND 24D IN CALLUS CULTURES OF HAPLOPAPPUS GRACILIS (NUTT) GRAY (INDIAN J EXP BIOL 14, 524-526). EFFECTS OF SOME HERBICIDES ON PLANT CHROMOSOMES (PROC INDIAN NATL SCI ACAD PART B 42, 299-307). EFFECT OF 24D ON MEIOTIC CHROMOSOMES OF HELIANTHUS ANNUUS L CV "PEREDOVICK" (LETT BOT (2), 91-94). AHMAD R ALIGARH MUSLIM UNIV ALIO CYTOLOOICAL STUDY OF THE EFFECTS OF COLCHICINE, IND0LE-3-ACETIC ACID, POTASSIUM CYANIDE AND 24D ON PLANT CELLS (J ELISHA MITCHELL SCI SOC 64, 117-125). NUMBER DATE DOCUMENT 667 00/00/69 AUTHOR: ROJIK I ADDRESSEE: COPYEE: DOCUMENT 668 00/00/85 AUTHOR: RASHID KA ADDRESSEE: COPYEE: DOCUMENT 669 J0/00/72 AUTHOR: POLIVTSEV FP ADDRESSEE: COPYEE: DOCUMENT 670 00/00/77 AUTHOR POHLHEIM E ADDRESSEE: COPYEE: DOCUMENT 671 00/00/72 ^ AUTHOR: PENNER D ADDRESSEE: COPYEE: DOCUMENT 672 00/00/77 AUTHOR: PALIKOHA E ADDRESSEE: COPYEE: DOCUMENT 673 0/00/75 v/ AUTHOR: NAKAI Y ADDRESSEE: COPYEE: O a CD TYPE PAGES 1 HORVATHMESZAROS M TITLE PAGE 98 THE EFFECT OF THE SODIUM SALT 24D ON THE CELL DIVISION OF VICIA FABA AND PISUM SATIVUM SEEDLINGS (BOT KOZL 56, 245-250). LONTAI I BABISH JG POTENTIAL OF 24D CONJUGATES AS PROMUTAGENS IN SALMONELLA MICRQSOME MUTAGENICITY TEST (J ENVIRON SCI HEALTH PART B PESTIC FOOD CONTAM AGRIC HASTES 19(8-9), 689-702). MUMMA RO UNIV SALAH ADDEEN IRAQ 1 VOITOVICH KA ACTION OF CHEMICAL MUTAGENS ON SEED PROGENY OF GRAPES STUDIED TO PRODUCE FORMS IMMUNE OR HIGHLY RESISTANT TO PHYLLOXERA AND MILDEH (KHIM JUTAGENEZ SOZDANIE SELEKTS MATER, 345-347). INST IM FRUNZE KISHINEV POHLHEIM F 1 MUTAGENICITY TESTING OF HERBICIDES WITH A HAPLOID PELARGONIUM (MUTAT RES 46(3),232). GUNTHER G 1 ROLE OF PH IN THE OBSERVED EFFECT OF PLANT GROWTH REGULATORS ON DNA (PHYTOCHEMISTRY 11, 3135-3138). EARLY RW 1 TESTING OF THE MUTAGENIC ACTION OF SOME HERBICIDES APPLIED ON CEREAL CROPS (MARER SES NAUK INST OCHR ROSL (POZNAN) 17,133-147). INST OCHR ROSL SOSNICOHI SHIMADA T IN VITRO CULTURE OF WHEAT TISSUES 2. MORPHOLOGICAL,CYTOLOGICAL AND ENZYMATIC VARIATIONS INDUCED IN WHEAT CALLUS BY GROWTH REGULATORS, ADENINE SULFATE AND CASEIN HYDROLYSATE (JPN J GENETdD ENGAKU ZASSHI 50, 19-31). NUMBER DOCUMENT 674 S DATE 00/00/72 AUTHOR * NAGL H ADDRESSEE COPYEE DOCUMENT 6 7 5 ^ 00/00/60 AUTHOR HUEHLING GN ADDRESSEE COPYEE DOCUMENT 676 ^ 00/00/80 TYPE PAGES 1 RUECKER H VANTHOF J 1 1 AUTHOR MORI S NAKANISHI H KYOTO PREFECT UNIV KYOTO ADDRESSEE COPYEE DOCUMENT ( . I I S ' 00/00/73 AUTHOR MOHANDAS T ADDRESSEE COPYEE GRANT MF DOCUMENT 678 00/00/72 AUTHOR: MOHANDAS T ADDRESSEE: COPYEE: GRANT NF DOCUMENT 679 S 00/00/59 AUTHOR MELCHERS G ADDRESSEE COPYEE BERGMANN L DOCUMENT 680 S ' 00/00/60 AUTHOR: MCMAHON RM ADDRESSEE: COPYEE: WITKUS ER CJ1 TITLE PAGE 99 RELATIONS BETWEEN MORPHOGENESIS AND NUCLEAR DNA CONTENT IN ASEPTIC CULTURES OF CYMBIDIUM AND THEIR CHANGE BY GROHTH REGULATORS (Z PFLANZENPHYSIOL 67, 120-139). CYTOLOGICAL EFFECTS OF HERBICIDAL SUBSTITUTED PHENOLS (HEEDS 8, 173-181). WILSON GB GRIGSBY BH EFFECTS OF MUTAGENS ON CULTURED CELLS OF HIGHER PLANTS II. RADIOSENSITIVITY IN CALLUS TISSUES OF PHASEOLUS VULGARIS CV KENTUCKY WONDER (KYOTO-FURITSU DAIGAKU GAKUJUTSU HOKOKY NOGAKU (32), 1-7). SHIOJIRI S MURAKAMI M A RELATIONSHIP BETWEEN NUCLEAR VOLUME AND RESPONSE TO AUXIN HERBICIDES FOR SOME WEED SPECIES (CAN J BOT 51, 1133-1136). CYTOGENETIC EFFECTS OF 29D AND AMITROLE IN RELATION TO NUCLEAR VOLUME AND DNA CONTENT IN SOME HIGHER PLANTS (CAN J GENET CYTO L 19(9), 773-783). MCGILL UNIV QUEBEC STUDIES ON THE CULTURE OF HAPLOID TISSUES OF ANTIRRHINUM MAJUS (BER DTSCH BOT GES 71, 959-973). SOME CYTOLOGICAL CHARACTERISTICS OF 29D INDUCED MITOSIS IN POLYPLOID CELLS OF SOLANUM TUBEROSUM (CARYOLOGIA 12, 398-903). BERGER CA NUMBER DATE DOCUMENT 6 8 1 ^ 00/00/77 AUTHOR: MAHER EP ADDRESSEE' COPYEE: DOCUMENT 682 y*/oO/OOs76 AUTHOR' NUTI RV ADDRESSEE: COPYEE: DOCUMENT 683 ^ 00/00/82 AUTHOR: MA TH ADDRESSEE' COPYEE: / DOCUMENT 684 00/00/78 AUTHOR: LOGVINENKO VF ADDRESSEE: COPYEE: DOCUMENT 685 \ / 00/00/73 AUTHOR: LIBBENGA KR ADDRESSEE' COPYEE: DOCUMENT 686 V 00/00/76 AUTHOR: LIN Y ADDRESSEE: COPYEE: DOCUMENT 687 \ / 00/00/69 AUTHOR: LIANG GHL ADDRESSEE: COPYEE: TYPE PAGES 1 MARTINI G 1 1 MORGUN VV 1 TORREY JO 1 KUO P 1 FELTNER KC 1 TITLE PAGE 100 RESISTANCE TO 24D IN ARABIDOPSIS THALIANA CARABIDOPSIS INF SERV 14, 18-21). GENOTYPE HORMONE INTERACTION IN THE INDUCTION OF CHROMOSOME ABERRATIONS; EFFECT OF 24D AND KINETIN ON TISSUE CULTURES FROM NICOTIANA SPP (MUTAT RES 36, 67-72). BUIATTI M VICIA CYTO GENETIC TESTS FOR ENVIRONMENTAL MUTAGENS A REPORT OF THE USA ENVIRONMENTAL PROTECTION AGENCY GENE-TOX PROGRAM (MUTAT RES 99(3), 257-272). STUDY OF THE MUTAGENIC EFFECT OF SOME PESTICIDES ON THE DURUM SPRING WHEAT (TSITOL GENET 12(3), 207-212). INST MOL VIOL GENET KIEV HORMONE INDUCED ENDOREDUPLICATION PRIOR TO MITOSIS IN CULTURED PEA ROOT CORTEX CELLS (AM J BOT 60, 293-299). PHYTOTOXICITY OF 24D ON THE DEVELOPMENT OF ROOT STOCK OF TAIWAN PAULOWNIA (KUO LI TAI-WAN TA HSUEH NUNG HSUEH YUAN YEN CHIU PAO KAO 16(2), 45-53). RIN U TAIWAN UNIV TAIHAN MEIOTIC AND MORPHOLOGICAL RESPONSE OF GRAIN SORGHUM TO ATRAZINE, 24D, OIL, AND THEIR COMBINATIONS (WEED SCI 17, 8-12). RUSS OG NUMBER DATE DOCUMENT 688 ^ 00/00/71 AUTHOR: LEFFLER HR ADDRESSEE* COPYEE* DOCUMENT 689 00/00/77 AUTHOR* KULKARNI VS ADDRESSEE* COPYEE* DOCUMENT 6 9 0 ^ 00/00/70 AUTHOR* KULIKOV BN ADDRESSEE: COPYEE: DOCUMENT 691 ^ 00/00/85 AUTHOR* KHALATKAR AS ADDRESSEE* COPYEE: DOCUMENT 692 00/00/72 AUTHOR* KERTESZ J ADDRESSEE' COPYEE* DOCUMENT 693 AUTHOR* KAR S ADDRESSEE: COPYEE* 00/00/75 DOCUMENT 699 ^ 00/00/71 AUTHOR: KALLACK H ADDRESSEE* COPYEE: t) O VXi CD TYPE PAGES 1 OBRIEN TJ P A T H VP 1 EZERZHA AA 1 BHARGAVA YR 1 MOLNAR A 1 1 1 YARVEKYLG L TITLE PAGE 101 ENHANCED DEOXRIBONUCLEIC ACID POLYMERASE ACTIVITY OF CHROMATIN FROM SOYBEAN HYPOCOTYLS TREATED WITH 24D (PLANT PHYSIOL 48,43-45). GLOVER DV CHERRY JH EFFECTS OF AGROCHEMICALS ON TETRAPLOID AND HEXAPLOID WHEATS (BIOVIGYANAM 3, 161-169). DEODIKAR GB EFFECT OF 240 ON HEAT DENATURATION TEMPERATURE OF DNA AND CHROMOSOME APPARATUS OF PLANT CELLS (TRANSLATED FROM FIZIOL RAST 17, 1205-1208). OVCHINNIKOVA MI MOCHALKIN AI MUTAGENIC EFFECTS OF 24D ALONE AND WITH ETHYL METHANESULFONATE IN HORDEUM VULARE L (ENVIRON POLLUT SER A 38(1), 9-17). NAGPUR UNIV NAGPUR EFFECT OF THE SODIUM SALT OF 24D ON THE MITOTIC GROWTH OF YELLOW CORN (ACTA BIOL(SZEGED) 18, 131-133). HORVATH M CYTOGENETIC EFFECTS OF 24D ON PISUM SATIVUM (PROC INDIAN SCI CONOR 62, 122). ON THE CYTOGENETIC EFFECTS OF 24D ON PEA CALLUS IN CULTURE (ACTA BIOL ACAD SCI HUNG 22, 67-73). NUMBER DATE DOCUMENT 695 00/00/79 AUTHOR KALLAK H ADDRESSEE-' COPYEE: TYPE PAGES JARVEKULG L 1 DOCUMENT 00/00/81 1 AUTHOR: HARASHIMA S ADDRESSEE COPYEp : ONO K DOCUMENT 697 v AUTHOR: GUO C ADDRESSEE: COPYEE: 00/00/72 1 DOCUMENT 698 v 00/00/69 AUTHOR: GUENTHER G ADDRESSEE: COPYEE* RIESS P 1 DOCUMENT 699 00/00/72 1 AUTHOR: GRANT WF ADDRESSEE: COPYEE: MOHANDAS DOCUMENT 700 00/00/83 1 AUTHOR: FURUYA T K1TASATO UNIV JAPAN ADDRESSEE: COPYEE: YOSHIKAWA T DOCUMENT 701 V/'r0w0i,/00/78 AUTHOR: EHRENBERG L ADDRESSEE: COPYEE: 1 STOCKHOM UNIV SWEDEN TITLE PAGE 102 CULTURE OF PLANT TISSUES AS MODEL FOR MUTAGENICITY TESTING OF HERBICIDES (TARTU RIIKLIKU UL1K TOIM 499, 30-47). VAPPER M ESTABLISHMENT OF HAPLOID, DIPLOID AND MIXOPLOID CELL LINES FROM ISOLATED MICROSPORE CUTURES IN PEONY (JPN J GENET(IDENGAKU ZASSHI) 56,596). EFFECTS OF CHEMICAL AND PHYSICAL FACTORS ON THE CHROMOSOME NUMBER IN NICOTIAMA ANTHER CALLUS CULTURES (IN VITRO 7, 381-386). INFLUENCE OF 24D ON THE NUCLEIC ACID METABOLISM OF BEAN PLANTS (ABST XI INT BOT CONGR 80). CYTOGENETIC EFFECTS OF 24D AND AMITROLE IN RELATION TO NUCLEAR VOLUME AND DNA CONTENT IN SOME HIGHER PLANTS (CAN J GENET CYTOL 14(4), 773-783). STUDIES ON PLANT TISSUE CULTURES. PART 37. EFFECTS OF AUXINS ON GROWTH AND SAPONIN PRODUCTION IN CALLUS CULTURES OF PANAX GINSENG (PLANTA MED 47(3), 183-187). ISHII T KAJII K GENETIC EFFECTS OF CHLOROPHENOXY ALKANOIC ACIDS ON PLANTS (ECOL BULL 27, 186-189). NUMBER DOCUMENT 702 AUTHOR DEV K ADDRESSEE*. COPYEE: DATE 00/00/73 TYPE PAGES 1 DOCUMENT 703 ^ ^ 0 0 / 0 0 / 7 7 AUTHORt DAS B ADDRESSEE COPYEE: DOCUMENT y 704 00/00/75 SINGH PK 1 1 AUTHOR: BUTCHER DN ADDRESSEE COPYEE: SOGEKE AK DOCUMENT 7 0 5 l'/^ 0 0 / 0 0 / 7 5 AUTHOR: BAYLISS MW ADDRESSEE: COPYEE: 1 DOCUMENT 7 0 6 0 0 / 0 0 / 7 7 AUTHOR: BAYLISS MW ADDRESSEE: COPYEE: 1 DOCUMENT 707 00/00/83 1 AUTHOR: ADDRESSEE COPYEE: AMIROVA FD INST BOT IM KOMAROVA ALIEV AA BAK l/ DOCUMENT 708 00/00/74 AUTHOR: AMER SM ADDRESSEE: COPYEE-' ALI EM 1 TITLE PAGE 103 E F F E C T S O F S O M E H E R B I C I D E S ON T H E S T U R C T U R E AND BEH A V I O R OF PLANT CHROMOSOMES (PROC INDIAN SCI CONGR 60, 308). MUTAGENICITY OF PESTICIDES IN BLUE GREEN ALGAE (MICROBIOS LETT 19-20, 103-107). RICE RES INST CUTTACK IN FACTORS INFLUENCING CHANGES IN PLIODY AND NUCLEAR DNA LEVELS IN CELLS FROM NORMAL, CROHN-GALL AND HABITUATED CULTURES OF HELIANTHUS ANNUUS L). TOMMERUP IC EFFECTS OF GROWTH IN VITRO ON THE CHROMOSOME COMPLEMENT OF DAUCUS CAROTA SUSPENSION CULTURES (CHROMOSOMA 51, A01-411). EFFECTS OF 24D ON GROWTH AND MITOSIS IN SUSPENSION CULTURES OF D A U C U S C A R O T A (PLANT SCI L E T T 8, 99-103). EFFECT OF THE SYSTEMIC HERBICIDE 2AD VALERIC ACID ETHYLENE GLYCOL MIXED ESTER ON CYTOGENETIC AND SOME PHYSIOLOGICAL PARAMETERS OF A L L I U M F I S T U L O S U M L. S E E D S ( D E P O S I T E D DOC, ISS V I N I T I 3183-3183). ARSHAVA EA I B R A G I M O V FI C Y T O L O G I C A l E F F E C T S OF P E S T I C I D E S 5. E F F E C T S OF S O M E H E R B I C I D E S ON VICIA FABA (CYTOLOGIA 39, 633-6A3). NUMBER DOCUMENT 709 DATE 00/00/82 AUTHOR: ALNAJJAR NR ADDRESSEE COPYEE: DOCUMENT 710 \ / 'S 00/00/72 AUTHOR: ADAMSON D ADDRESSEE: COPYEE: D O C U M E N T 711 S '0[0 / 0 0 / 7 5 AUTHOR: WINELL M ADDRESSEE: COPYEE DOCUMENT 712 00/00/75 AUTHOR HAAG D ADDRESSEE: COPYEE: DOCUMENT 713 ^ 00/00/76 AUTHOR ADDRESSEE: COPYEE: KOSNTANTINOVA TK RALPH MCELROY CO DOCUMENT 714 00/00/76 AUTHOR: ANNA RM ADDRESSEE: COPYEE: DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 715 AMMA 00/00/76 RM O .- O (T' TYPE PAGES 1 SOLIMAN AS TITLE PAGE 104 C Y T O L O G I C A L E F F E C T S OF H E R B I C I D E S 1. E F F E C T O F 2 4 D A N D 245T ON ME I O T I C CELLS OF WHEAT AND TWO RE L A T E D SP E C I E S (CYTOLOGIA 47, 53-61). HINDE R 1 DNA ANALYSIS OF AUXIN TREATED JERUSALEM ARTICHOKE TUBER TISSUE AS A SCREEN FOR THE EVALUATION OF SUBSTANCES INFLUENCING CELL DIVISION (PLANT GROWTH SUBST PROC INT CONT 7TH(1970), 428-434) KAMISAKA S 2 AN INTERNATIONAL COMPARISON OF HYGIENIC STANDARDS FOR CHEMICALS IN THE WORK ENVIRONMENT (AMBIO 1975, 34-35). 13 GOERTTLER K THE INFLUENCE OF NON CYTOTOXIC CONCENTRATIONS OF THE HERBICIDE 24D ON T H E DNA S Y S T H E S I S IN C U L T U R E D V E R T E B R A T E C E L L S t A R C H TOXICOL 33, 84-102). PREISS D UNIV HEIDELBERG TEILINST 7 EFIMENKO LP EMBRYOTROPIC EFFECT OF THE PRODUCTS FROM THE DECOMPOSITION OF HERBICIDES BASED ON 24D (EMBRIOTROPNOE DEISTVIE PRODUKTOV RAZLOZHENIYA GERBITS IDOV NAOSNOE 2,4-DIKLORFENOKSIUKSUSNOI K I S L O T Y H T R ANSLATED FROM R U S S I A N M G I O I SANIT 11, 102-105). ANTONENKO TA MINISTRY OF HEALTH RSFSR 1 EFFECT OF 24D ON RABBIT DUODENUM (INDIAN J PHYSIOL PHARMACOL 20(3), ^ 153-155MPEST ABSTRACTS 78-1865). FRANCIS CM MED COLL TRIVANDRUM INDI FRANCIS CM 3'^ EFFECT OF 24D ON RABBIT DUODENUM. MEDICAL COLLEGE TRIVANDR NUMBER DOCUMENT 716 DATE 00/00/76 AUTHOR * REMANOMSKI H ADDRESSEE" COPYEE! / DOCUMENT 717 00/00/73 AUTHOR: CHANG HC ADDRESSEE! COPYEE: DOCUMENT 718 V/ 00/00/73 AUTHOR! BALOBANGA MJ KOCSIS F ADDRESSEE! COPYEE! / v DOCUMENT 719 00/00/73 AUTHOR! KOLBERG J ADDRESSEE! COPYEE y DOCUMENT 720 00/00/74 AUTHOR! AXELSON 0 ADDRESSEE! COPYEE: DOCUMENT 721 j/^00/00/74 AUTHOR! BALOBANGA MJ KOCSIS F ADDRESSEE: COPYEE: DOCUMENT 722 `^ 0 0 / 0 0 / 7 4 AUTHOR: ARKHIPOV GN ADDRESSEE! COPYEE: ... o *-- * -A TYPE PAGES TITLE PAGE 103 EFFECT OF 24D ON THE ABSORPTION AND EXCRETION OF CHLOROCHOLINE CHLORIDE (CCC) IN RATS (ANN UNIV MARIAE CURIE SKLODOWSKI SECT D 31(43),333-338)(PEST ABSTRACTS 79-0617) ACAD MED LUBLIN POLAND RIP JW 1 EFFECTS OF PHENOXYACETIC ACIDS ON RAT LIVER TISSUES (INCOMPLETE DOCUMENT). CHERRY JH ANTONI F 1 J EFFECT OF 24D ON SEMICONSERVATIVE AND DNA REPAIR SYSTHESES. BULLOUS DERMATITIS AFTER EXPOSURE TO 24D (BER OESTERR STUDIENGES ATOMENERG SGAE BER 2218, 1-7). ALTMANN H VINCZE I ILLEGIBLE ILLEGIBLE - 24D AND 245T - ALBUMIN (ACTA PHARMACOL TOX 33, 470-47?)(6348). SUNDEIL L 1 HERBICIDE EXPOSURE, MORTALITY AND TUMOR INCIDENCE. AN EPIDEMIOLOGICAL INVESTIGATION ON SWEDISH RAILROAD WORKERS (WORK ENVIRON - HEALTH 11(1), 21-28HIND HYGIENE DIGEST, 21)(1005/74). ANTONI F 1 ^ EFFECT OF 24D ON SEMICONSERVATIVE - AND DNA - REPAIR SYSTHESIS. BULLOUS DERMATITIS AFTER EXPOSURE TO 24D (BER OSESTERR STUDIENGES ATOMENERG 1973, SGAE BER 2218, 1-7)(TOXICOLOGY 81, 79)(10307S). ALTMANN H VINCZE I KOZLOVA IN 5. CARCINOGENIC PROPERTIES OF HERBICIDE 24D AMINE SALT (VOPROSY PITANIIA, MOSCOW 5, 83-84)(0RIGINAL ARTICLE AND TRANSLATION). LIVAL J NUMBER /f)ATE DOCUMENT AUTHOR-ADDRESSEE COPYEE 723 V 00/00/00 DOCUMENT 729 J 05/17/83 AUTHOR s-- M I L L E S LABS MERCIECA MD RODWELL DE ADDRESSEE COPYEE DOCUMENT 725 ) 05/26/83 AUTHOR V ^ _ X G N N E R JD JR ADDRESSEE COPYEE DOCUMENT AUTHOR ADDRESSEE COPYEE ) /7 2 6 i f 09/12/83 HAZLETON LABS MACHOTKA SV BURNS CJ DOCUMENT/ AUTHOR I ADDRESSEE: COPYEE! 727 / 01/21/85 HAZLETON LABS DOCUMENT/ 09/12/83 AUTHOR! fTON LABS iOTKA SV "COLPEAN BR ADDRESSEE: COPYEE DOCUMENT AUTHOR ADDRESSEE COPYEE 729 10/19/80 RAMSEY JC BRAUN MH -0 H"* O- ro TYPE PAGES 2 TITLE PAGE P.03 NO. 980 (LIST OF TRANSLATIONS OF JOURNAL ARTICLES). 106 NEMEC MD SIGLER FW 110 A RANGE FINDING TERATOLOGY STUDY IN FISCHER 399 RATS HITH 29D FINAL REPORT PROJECT NUMBER MIL-22002. KOPP SE LE1ST PL KING SG TASKER EJ 1 MEMORANDUM RE A RANGE FINDING TERATOLOGY STUDY IN FISCHER 399 RATS WITH 29D. MCKENNA CONNER S CUNEO SNYDER FG DAWKINS BO 103 v / SUBCHRONIC TOXICITY STUDY IN RATS 29D FINAL REPORT. SEROTA DG BURDOCK GA AL5AKER RD HEPNER KE SEROTA DG 5 SUBCHRONIC TOXICITY IN RATS 29D ADDENDUM TO FINAL REPORT. MACHOTKA SV SNYDER FD DAWKINS BG 80 SUBCHRONIC TOXICITY STUDY IN MICE 29D FINAL REPORT. SEROTA DG BURDOCK GA ALSAKER RD HEPNER KE SMITH FA DOW 18 [ s ' DO S E L E V E L S OF 2 9 D IN F O R E S T W O R K E R S H E T K - 0 0 2 3 7 2 - ( 2 7 ). LAVY TL PARK CN NUMBER DATE TYPE PAGES DOCUMENT AUTHOR* ADDRESSEE COPYEEs 730 INTL MYER 10/09/81 RES AND DEVELOPMENT JR BENSON BW JOHNSON DE 27 PTTLE PAGE DETERMINATION OF ACUTE DERMAL LD50 IN RABBITS 29D TECHNICAL. MARROqUIN F RICHTER HR 107 DOCUMENT AUTHORS ADDRESSEE: COPYEEs 7 3 1 1 / 10/09/81 , INTr RES AND DEVELOPMENT URIAH LC MYER JR JOHNSON DE ^ S 30 V DETERMINATION OF ACUTE ORAL LD50 IN FISCHER 399 RATS 29D TECHNICAL. RICHTER HR BENSON BM DOCUMENT 732 03/02/83 AUTHOR NIL RES LAB ADDRESSEE: COPYEEs DOCUMENT AUTHORS ADDRESSEE! COPYEEs y 733 06/09/98 ADAMS EM 177 A TERATOLOGY STUDY IN FISCHER 399 RATS WITH 29D FINAL REPORT PROJECT NUMBER NIL-81135. IRISH DD y TOXICOLOGY AND HYGIENE; 29D T23.19-11-19. DOW DOCUMENT 739 Z 01/00/81 AUTHOR! ADDRESSEE? COPYEEs ONTARIO HYDRO WATSON DA LIBICH S 39 A STUDY TO ASSESS THE OCCUPATIONAL EXPOSURE TO 29D HERBICIDES REPORT SSD-81-1. TO JC WONG KY DOCUMENT 735 02/00/86 AUTHOR! HIKLUND K ADDRESSEE! COPYEEs HOLM LE 7 u ^ ^ S O F T TISSUE SARCOMA RISK IN SWEDISH AGRICULTURAL AND FORESTRY WORKERS (JOUR OF THE NATL CANCER INST 76(2), 229-239). KAR0L1NSKA HOSPITAL AND DOCUMENT 736 00/00/85 AUTHORS RIVAROLA VA ADDRESSEES COrYEE: ^ 3 DOCUMENT 737 U//^ 0 0 / 0 0 / 0 0 AUTHOR! JL SARGENT M ILLEGIBLE -0 ADDRESSEE! -0 COPYEEs O 00 BERGESSE JR DNA AND PROTEIN SYSTHESIS INHIBITION IN CHINESE HAMSTER OVARY CELLS BY DICHLOROPHENOXYACETIC ACID (TOXICOLOGY LETTERS 29, 137-199). BALEGNO HF UNIV NACIONAL DE RIO CUA BLAZEK D PURDUE UNIV 1 THE TOXICITY OF 29D AND PICLORAM HERBICIDES TO FISH. ELDER JH M O R R E DJ NUMBER DOCUMENT 738 DTt V^n0 2 / 2 6 / 8 6 AUTHOR' HALL JM ADDRESSEE* COPYEE: DOCUMENT 739 00/00/85 AUTHOR: ANTONENKO TA ADDRESSEE: COPYEE! DOCUMENT AUTHOR: ADDRESSEE! COPYEE-- 740 V ADAMS 06/25/47 DW DOCUMENT 741 10/19/44 AUTHOR: DUNN EC ADDRESSEE! COPYEE- DOCUMENT 742 v 00/00/00 AUTHORS ROWE VK ADDRESSEE! COPYEEs DOCUMENT 743 06/12/47 AUTHOR: ROHE VK ADDRESSEE: COPYEEs DOCUMENT AUTHOR: ADDRESSEE COPYEE: 744 ^ ADAMS 06/25/47 EH DOCUMENT AUTHOR: ADDRESSEE: COPYEE: fit) O o 745 ' 08/31/50 ROWE VK o TYPE RAO KS PAGES io ( y ERMOLOV VI 7 </ ROHE VK 2L ROHE VK 1 \J 6V MCCOLLISTER DD ADAMS EH 17 ROHE VK SPENCER H TITLE PAGE 108 2 4 D ACID A C U T E T O X I C O L O G I C P R O P E R T I E S H E T K - 0 0 2 3 7 2 - 0 4 3 P. (INCLUDES DATA SHEETS ON ACUTE ORAL TOXICITY, EYE IRRITATION TEST, AND SKIN IRRITATION TESTS). DON CERTAIN ASPECTS OF THE MECHANISM OF EMBRYOTROPIC EFFECTS OF 24D (GIGIENA I SANI T A R I A 10, 7 6 - 7 7 H O R I G I N A L A R T I C L E A N D TRANSLATION). KONSTATINOVA TK MINISTRY OF HEALTH OF RS RANGE FINDING TOXICOLOGICAL TESTS ON CHICKENS WITH 24D T23.14-11-1. DOW PRELIMINARY INFORMATION RELATIVE TO THE TOXICITY OF 24D (K2372-3) T23.14-11-1. DOW ACUTE ORAL TOXICITY OF 24D TO RATS, MICE, GUINEA PIGS AND CHICKS (INCLUDES HANDWRITTEN NOTES). SPENCER HC DOW THE TOXICOLOGICAL PROPERTIES OF 24D AND ITS SODIUM AND ALKANOLAMINE SALTS, AS REVEALED BY EXPERIMENTS UPON LABORATORY ANIMALS T23.14-11-1. DOW RANGE FINDING TOXICOLOGICAL TESTS ON CHICKENS WITH 24D T23.14-11-1. DOW RESULTS OF SEMICHRONIC ORAL TOXICITY STUDIES ON 24D T23.14-11-1. DOW NUMBER DATE DOCUMENT AUTHOR*. ADDRESSEE* COPYEE! 7A6 WHITE 0A/11/50 LC DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 7A7 v OA/15/51 MCCOLLISTER DD DOCUMENT 7A8 10/11/50 AUTHOR: ADAMS 1H ADDRESSEE COPYEE: DOCUMENT 7A9 00/00/70 AUTHOR: COPE OB ADDRESSEE: COPYEE: DOCUMENT 07/00/7A AUTHOR: BURTON JA ADDRESSEE: COPYEE: DOCUMENT AUTHOR: ADDRESSEE: COPYEE-* 751*/ EPA 11/00/82 DOCUMENT AUTHOR: ADDRESSEE COPYEE: 752 \ EPA 10/00/82 DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 753 v / 01/23/81 h**4 OO OT TYPE DOW HES PAGES 1' 1/ ROWE VK WOOD EM X' A GARDINER TH A 2 TITLE 245T ACID. PAGE 109 24D REQUEST FOR BIOLOGICAL TEST RGH DOW RESULTS OF SKIN IRRITATION AND SKIN SENSITIZATION TESTS CONDUCTED ON HUMAN SUBJECTS WITH OLD AND NEW PREPARATIONS OF 24D T23.14-11-6. DOW SOME CHRONIC EFFECTS OF 24D ON THE BLUEGILL (ILLEGIBLE) (TOX AND PHARMACOLOGY, 229). WALLEN GH BUR OF SPORT FISHERIES A A B S O R P T I O N OF HERB I C I D E S FROM T H E RAT LUNG CARCH ENVIRON HEALTH 29, 31-33). SCHANKER LS UNIV OF MO KANSAS CITY 24D FACT SHEET. 24D FACT SHEET. FACT SHEET ON 24D NUMBER DOCUMENT AUTHOR: ADDRESSEE COPYEE: 754 V DATE 04/22/80 TYPE PAGES 9'/ TITLE 24D FACT SHEET PAGE 110 DOCUMENT AUTHOR: ADDRESSEE: COPYEE'- 09/00/84 11 v COMMENTS ON THE IMPROBABILITY OF 24D AS A CAUSE OF PERIPHERAL NEUROPATHY. DOCUMENT 756 00/00/77 AUTHOR: YOUNG JF ADDRESSEE: COPYEE' HALEY T J 12v / PHARMACOKINETIC STUDY OF A PATIENT INTOXICATED NITH 24D AND 2-METH0XY-3,6-DICHLOROBENZOIC ACID (CLINICAL TOX 11(3), 489-500). HEN DOCUMENT 757 04/00/72 AUTHOR: ILLEGIBLE ADDRESSEE COPYEE: ^ A METHOD FOR DETERMINATION OF LON LEVELS OF EXPOSURE TO 24D AND 245T (ILLEGIBLE)(HEALTH ASPECTS OF PESTICIDES ABSTRACT BULLETIN 5(4), 192)(72-0845). DOCUMENT 758 04/00/72 AUTHOR: ANONYMOUS ADDRESSEE COPYEE: ECOLOGICAL EFFECTS OF THE WAR IN VIETNAM (ILLEGIBLE)(HEALTH ASPECTS OF PESTICIDES ABSTRACT BULLETIN 5(4), 169X72-0743). DOCUMENT 759 03/00/82 AUTHOR: VAINIO H ADDRESSEE: COPYEE: NICKELS J 5 PHENOXY ACID HERBICIDES CAUSE PEROXISOME PROLIFERATION IN CHINESE HAMSTERS (SCAND J W O R K ENVIRON H E ALTH 8, 70-73). LINNAINMAA K INST OF OCCUPATIONAL HEA DOCUMENT 760 v / / "oO/00/76 AUTHOR: CENCI P UNIV OF FERRARA ITALY ADDRESSEE: COPYEE: CAVAZZINI G EFFECTS OF 24D (SODIUM SALT) ON REPRODUCTIVE PROCESSES IN MICE (NUOVE ANN IS MICROBIOL 27(6), 569-584). CORRADINI L MARCATI F OO 05 NUMBER DATE DOCUMENT 761 01/00/64 AUTHOR: ADDRESSEE COPYEE: CLARK DE MCLARAN JK DOCUMENT AUTHOR: ADDRESSEE COPYEE: 762 SMITH DOW 12/09/80 FA DOCUMENT 763 01/31/59 AUTHOR: APFFEL CA ADDRESSEE: COPYEE: DOCUMENT 764 11/07/59 AUTHOR: ADDRESSEE: COPYEE: GOLDSTEIN NP MAYO FOUNDATION D OCUMENT 765 v / 100/ 00/00 AUTHOR ADDRESSEE: COPYEE: DOCUMENT 766 09/00/72 AUTHOR: ADDRESSEE: COPYEE: SARGEANT M ILLEGIBLE document 767 00/00/76 AUTHOR: ADDRESSEE COPYEE: BUSLOVICH SY O O <1 Vx) TYPE PAGES 5 YOUNG JE USDA TITLE PAGE 111 ANIMAL METABOLISM OF HERBICIDES THE FATE OF 24D IM SHEEPtAG AND FOOD CHEMISTRY 12(1), 43-45). Y OUNGER RL HUNT LM HERMANN EA PHARMACOKINETICS OF 24D IN FISCHER 344 RATS HET K-002372-(24). RAMSEY JC BRAUN WH 20 ^ CYTOSTATIC EFFECT OF CERTAIN AUXINS PRELIMINARY REPORT!ACTION CYTOSTATIQUE DE CERTAINES A U X I N E S M L A PRESSE MEDICALE 67(6), 207-209)(ORIGINAL ARTICLE AND TRANSLATION). JONES PH UNIV OF MN 4 PERIPHERAL NEUROPATHY AFTER EXPOSURE TO AN ESTER OF DICHLOROPHENUXYACETIC ACID (JOUR AM MEDICAL ASSOC 171, 1306-1309). BROWN JR MAYO CLINIC 1^ THE FOLLOWING IS A REPORT ON ODOR AND TASTE THRESHOLDS AS REQUESTED. 2 BLAZEK D PURDUE UNIV THE TOXICITY OF 24D AND PICLORAM HERBICIDES TO FISH (PROC INDIANA ACAD SCI, 114-123)(HEALTH ASPECTS OF PESTICIDES ABSTRACT BULLETIN 5(9),453)(72-1950). ELDER JH MOTTE DJ 1 ALEKSASHINA 2A EMBRYOTOXIC EFFECT OF HERBICIDES ACIDS (ZDRAVOOKHR GELORUSS (10), 78-2207). KOLOSOVSKAYA VM - CHLORINE DERIVATIVES OF PHENOXY 83-84)(PESTICIDES ABSTRACTS NUMBER DOCUMENT 768 08/31/50 AUTHORi ADDRESSEE COPYEE DRILL VA DOM TYPE PAGES WAYNE UNIV TITLE PAGE 112 INTERIM REPORT ON THE ACUTE AND SUBACUTE ORAL TOXICITY OF 29D FOR DOGS T23.19-11-5. SPENCER AC ROHE VK DOCUMENT 769 11/07/59 AUTHOR ADDRESSEE COPYEE GOLDSTEIN NP MAYO FOUNDATION JONES PH UNIV OF MN A PERIPHERAL NEUROPATHY AFTER EXPOSURE TO AN ESTER OF DICHLOROPHENOXYACETIC ACIDCJOUR OF AM MEDICAL ASSOC 171, 1306-1309). BROWN JR MAYO CLINC DOCUMENT 770 07/00/81 AUTHOR AM COUNCIL ON SCIENCE AN ADDRESSEE COPYEE DOCUMENT H 771 ^ 00/00/70 AUTHOR ADDRESSEE COPYEE COMMITTEE ON COMMERCE DOCUMENT AUTHOR ADDRESSEE COPYEE 772 y 00/00/71 ANONYMOUS 109 V * THE HEALTH EFFECTS OF HERBICIDE 295T, A REPORT BY THE AMERICAN COUNCIL ON SCIENCE AND HEALTH. 1 THE EFFECTS OF 295T AND RELATED HERBICIDES ON MAN AND THE ENVIRNMENT (ILLEGIBLEH9296) 1V HERBICIDES 'SECRET* 295T REPORT (CHEM ENO NEWS 99(29), 15). DOCUMENT 00/00/72 AUTHOR ADDRESSEE COPYEE DOCUMENT MAIERBODE H y 779 00/00/72 AUTHOR ANONYMOUS ADDRESSEE COPYEE 1 THE PROBLEM OF USING 295T (ANZ SCHAEDLINGSK PFLANZENSCHUTZ 95(1), 2 - 6 H C H E M I C A L ABSTRACT 77, 1 3 9 H 1 5 0 7 1 N ) . FRIEDRICHWILHELMS UNIV G 1 NO'HERBICIDE RESIDUES IN MEAT (AGR RES - I L L E G I 8LEHTOX AND PHARMACOLOGY, 553). Sb H * OO 00 HUMBER DATE DOCUMENT 775 ^ 0 0 / 00/72 AUTHORi PIPER WN ADDRESSEE COPYEE DOCUMENT 776 03/00/76 AUTHOR MAIERBODE H ADDRESSEE COPYEE DOCUMENT 777 ^ 00/00/00 AUTHOR DOUGHERTY WH ADDRESSEE COPYEE: y DOCUMENT 778 V' 0 0 / 00/72 AUTHOR SJODEN PO ADDRESSEE COPYEE DOCUMENT 779 V ^ o o / 0 0 / 7 2 AUTHOR MAIERBODE H ADDRESSEE COPYEE: DOCUMENT 7 8 0 ^ ^ 00/00 / 7 2 AUTHOR: FYTIZASDANIELIDOU ADDRESSEE COPYEE: DOCUMENT 781 v ^ ^ o o / 0 0 / 0 0 AUTHOR: ADDRESSEE: COPYEE: DOCUMENT 78 2 ^ 00/00/71 AUTHOR: MOORE JA ADDRESSEE: COPYEE: /c> aJ>-- O to TYPE ROSE JQ PAGES 1^ TITLE PAGE 113 METABOLISM OF 2A5T IN RATS (TOXICOL APPL PHARMACOL 22(2), 3 1 7 K T O X AND PHARMACOLOGY, 272). GEHRING PJ DOW 1 ^ THE 245T QUESTION ( 2 7 7 6 H A N Z SCHAEDLINGSKD PFLANZENSCHUTZ A5(l), 2 - 6 K B I 0 S I S ABSTRACTS OF ENVIRONMENTAL POLLUTANTS 5(3)). FRIEDRICHWILLHELMS UNIV GOLDBERG L NON-TERATOGENICITY OF 2A5T IN MONKEYS (MUCACA MULATTA) (ABSTRACTS TWELFTH ANNUAL MEETING, A42). ILLEGIBLE SODERBERG U SEX DEPENDENT EFFECTS OF PRENATAL 245T ON RATS OPEN FIELD BEHAVIOR (PHYSIOL BEHAV 9(3), 357-360)(132486H). ULLERAKE3 HOSPITAL SHEDE 1 THE PROBLEM OF USING 245T (ANZ SCHAEDLINGSK PFLANZENSCHUTZ A5(l), 2-6H15071N). FRIEDRICHWILHELMS UNIV G 1 U - -- THE EFFECT OF THE HERBICIDE 2A5T ON WHITE RATS DURING - ILLEGIBLE (ANN INST PHYTOPATHOL BENAKI). INST PHYTOPATHOL ATHENS 1 INCOMPLETE DOCUMENT COURTNEY (CD TERATOLOGY STUDIES WITH THE TRICHLOROPHENOXYACID HERBICIDES, 2A5T AND SILVEX (TERATOLOGY A, 236). NATL INST OF ENVIRON HEA ojO'f''( NUMBER DATE DOCUMENT 783 00/00/71 AUTHOR: COLLINS IF ADDRESSEE COPYEE: y DOCUMENT 784 00/00/00 AUTHOR: ILLEGIBLE ADDRESSEE COPYEE DOCUMENT 785 00/00/71 AUTHOR ILLEGIBLE ADDRESSEE COPYEE DOCUMENT AUTHOR ADDRESSEE COPYEE 786 00/00/00 ILLLEGIBLE DOCUMENT y. 787 00/00/71 AUTHOR MOFFETT JO ADDRESSEE COPYEE DOCUMENT 788 00/00/71 AUTHOR C L A R K DL ADDRESSEE COPYEE DOCUMENT AUTHOR ADDRESSEE COPYEE y 789 w 00/00/71 COURTNEY KD DOCUMENT AUTHOR ADDRESSEE COPYEE 790 00/ 0 0 /0 0 ILLEGIBLE o PAGE 114 TYPE P A G E S , TT.'iE -------------------- ----------------------- ----- -- -- -------- -------------- ----- " ----------------------------------------------------------- 1^ TERATOGENIC STUDIES WITH 245T AND 24D IN THE HAMSTER (BULL ENVIRON CONTAM TOXICOL, 559-567J(TOX AND PHARMACOLOGY, 76). WILLIAMS CH FDA 1 245T QUESTION (ILLEGIBLE). 1 CYTOGENIC EFFECTS OF 245T ON OOGENESIS AND EARLY EMBRYOGENESIS (TOX AND PHARMACOLOGY, 28)(ILLEGIBLE). 2 / ILLEGIBLE. ILLEGIBLE V* TOXICITY OF AIRPLANE APPLICATIONS OF 24D, 245T AND A COTTON DESSICANT TO COLONIES OF HONEY BEES (ILLEGIBLE). PALMER JS 1 MORE ABOUT 245T - RESIDUAL ASPECTS OF 245T AND AN ESTER IN SHEEP A N D C A T T L E W I T H O B S E R V A T I O N S ON --- T O X I C O L O G I C A L EFFECTS (J AG FOOD CHEM 19(76). MOORE JA BUT 245T IN THE - ILLEGIBLE - (PHARMA 20, 556). 1 RENAL EXCRETION OF 245T IN THE RAT(RENALE AUSSCHEIDUNG VON 245T BEI RATTEN) -- ILLEGIBLE. NUMBER / DATE DOCUMENT 791V 00/00/00 AUTHOR: ILLEGIBLE ADDRESSEE* COPYEE* DOCUMENT 792 S 00/00/73 AUTHOR* SOKOLIK IY ADDRESSEE* COPYEE* DOCUMENT 793 s / 00/00/73 AUTHOR* KOLBERG J ADDRESSEE* COPYEE* DOCUMENT AUTHOR* ADDRESSEE* COPYEE* y 794 00/00/00 ILLEGIBLE D O C U M E N T 7 9 5 '^//^ 0 0/00/71 AUTHOR* PALMER JS ADDRESSEE: COPYEE: DOCUMENT 796 V / " 03/00/77 AUTHOR* K O S C H I E R IJ ADDRESSEE* COPYEE: DOCUMENT y 797 02/00/81 AUTHOR: BECK SL ADDRESSEE* COPYEE: TYPE PAGES 1 V' INST EXP M E D A C A D ME1 HELGELAND K 2 1` .S*'' 1 BERNDT HO 1K HHEATON COLLEGE TITLE PAGE 115 DIFFICULTY OF EVALUATING THE TOXICITY AND TERATOGENICITY OF 2A5T F R O M E X I S T I N G ANIMAL E X P E R I M E N T S --- I L L EGIBLE. THE EFFECT OF 2A5T AND ITS BUTYL ESTER ON RAT EMBRYOGENESIS CBYULL EK S P BIL M F D 76(7), 9 0 - 9 3 K 6 1 A 6 ). D SC BINDING OF 2AD AND 2A5T IN BOVINE SERUM ALBUMIN (ACTA PHARMACOL TOXICOL 33(5,6), A 7 0 - A 7 5 H 6 3 A 8 ) . JONSEN J UNIV OSLO ILLEGIBLE ASPECTS OF 2A5T AND AN ESTER IN SHEEP AND -ILLEGIBLE- TO T O X I C O L G I C A L E F F E C T S (J A G F O O D C H E M 19(A), 7 6 1 H P L A N T G R O W T H REGULATORS 25). STUDIES ON THE MECHANISM CA RENAL TRANSPORT DEPRESSION CAUSED P R E T R E A T M E N T W I T H 2A5T (J T O X E N V I R O N H E A L T H 2, 3 2 3 - 3 3 A H I N D HYGIENE DIGEST, 15). BY ASSESSMENT OF ADULT SKELETONS TO DETECT PRENATAL EXPOSURE TO 2A5T OR TRIFLURALIN IN MICE (TERATOLOGY 23(1), 33-55). HUMBER ATE .A DOCUMENT 798 n0n0 / 0 0 / 8 1 AUTHOR: HANIFY JA ADDRESSEE COPYEE! DOCUMENT 799 09/00/81 AUTHOR! COURTNEY KD ADDRESSEE: COPYEE-' DOCUMENT 800 09/00/81 AUTHOR! COURTNEY KD ADDRESSEE: COPYEE: ^ DOCUMENT AUTHOR: ADDRESSEE COPYEE: 801 ^ 00/00/82 E A T O N DL DOCUMENT AUTHOR: ADDRESSEE! COPYEE: 802 00/00/82 ILLEGIBLE DOCUMENT 803 ^ 12/00/82 AUTHOR: ADDRESSEE: COPYEE: ERIKSSON M AXELSON 0 DOCUMENT 804 06/00/84 AUTHOR! ADDRESSEE: COPYEE: RASHID KA CORNELL UNIV TYPE PAGES METCALF P I EBRON MT 14 / EBRON MT UNIV OF NA 1^ HARDELL L BABISH JG 6 O TITLE PAGE AERIAL SPRAYING OF 245T AND HOMAN BIRTH MALFORMATIONS; AN EPIDEMIOLOGICAL INVESTIGATION (PROFILE ID 11467T). NOBBS CL HORSLEY KJ 116 245T EFFECTS ON CARDIAC AND SERUM LACTIC DEHYDROGENASE CLDH) AND C R E A T I N E K I N A S E (CK) ISOZYMES II. NEON A T A L E N Z Y M E ACTI V I T I E S AND ISOZYME PROFILES (ARCH ENVIORN CONTAM TOX 10, 583-595). EPA 245T EFFECTS ON CARDIAC AND SERUM LACTIC DEHYDROGENASE (LDH) AND C R E A T I N E K I N A S E (CK) I S O Z Y M E S I. M A T E R N A L E N Z Y M E A C T I V I T I E S A N D ISOZYME PROFILES (ARCH ENVIRON CONTAM TOX 10, 571-581). EPA B ILIARY EXCRETION OF 245T IN T HE RAT (TOX LETTERS 14, 175-181). ILLEGIBLE (PROC UNIV OTAGO MED SCH 60(2) 31-32). ANOTHER LOOK AT THE CARCINOGENICITY OF 245T SOFT TISSUE SARCOMAS AND EXPOSURE TO CHEMICAL SUBSTANCES; A CASE REFERENT STUDY (BR J IND MED 38(27))(ABSTRACTS AND COMMENTS FOOD AND CHEM TOX 20(6), 973). BERG NO MOLLER T TESTING OF 245T-AMINO ACID CONJUGATES FOR MUT A G E N I C ACTIVITY IN SALMONELLA TYPHIMURIUM STRAINS (MUTATION RESEARCH 136(3), 217-221). MUMMA RO PA ST UNIV NUMBER DOCUMENT 805 v DATE 06/00/85 AUTHOR: ADDRESSEE! COPYEE: BAZARE JJ NATL CENTER FOR DOCUMENT 8 0 6 ^ 09/00/84 AUTHOR! KOVASZNAY BM ADDRESSEE! COPYEE: DOCUMENT y 807 v 00/00/81 AUTHOR: YOUNG JD ADDRESSEE: COPYEE: DOCUMENT 808 ^ ^ 0 5 / 2 8 / 7 1 AUTHOR: ADDRESSEE: COPYEE: DOCUMENT 809 00/00/73 AUTHOR: SJODEN PO ADDRESSEE: COPYEE: DOCUMENT ,,/ 810^ 00/00/82 AUTHOR: ADDRESSEE: COPYEE: LENG ML LA V Y TL DOCUMENT 811 01/00/80 AUTHOR: LAVY TL ADDRESSEE* COPYEE: t-- * CO ro J> TYPE PAGES \\/ YOUNG JF TITLE PAGE 117 245T PHARMACOKINETICS IN PREGNANT AND NONPREGNANT CD-I MICE (TERATOLOGY 31(3))CABSTRACTS THE TERATOLOGY SOCIETY 25TH ANNUAL MEETING). LEAMONS ML NELSON CJ , 1 JOHNS HOPKINS UNIV STUDY OF HEALTH EFFECTS OF HERBICIDES IN HIGHWAY MAINTENANCE WORKERS (DISSERTATION ABSTRACTS INTERNATIONAL 45(3)). RAMSEY JC PHARMACOKINETICS OF 245T PGBE ESTER APPLIED DERMALLY TO RATS (JOUR OF T O X A N D E N V I O R N H E A L T H 8, 401-408). BRAUN WH DOW 2 ^ PSAC HICCOUGHS OVER 245T - NEW WORLD (NATURE 231, 210-211). SODERBERG U 1^ SEX DEPENDENT EFFECTS OF PRENATAL 245T ON RATS OPEN FIELD BEHAVIOR (PHYSIOL BEHAV 9(3), 357-360KTOXICOLOY 78) 132486H. ULLERAKER HOPSITAL SWEDE RAMSEY JC UNIV OF AR 24 ' S REVIEW OF STUDIES WITH 245T IN HUMANS INCLUDING APPLICATORS UNDER FIELD CONDITIONS (ACS SYMPOSUIM SERIES, NO 182 PESTICIDE RESIDUES AND EXPOSURE). BRAUN WH DOW SHEPARD JS y FIELD WORKER EXPOSURE AND HELICOPTER SPRAY PATTERN OF 245T (BULL ENVIRON CONTAM TOXICOL 24, 90-06). BOUCHARD DC UNIV OF AR NUMBER DATE DOCUMENT 812 08/22/67 AUTHOR! KLIGMAN AM ADDRESSEE-' RONE VK COPYEE! DOCUMENT AUTHOR: ADDRESSEE! COPYEE: y 813 ^ 08/09/67 RONE VK KLIGMAN AM ROWE VK s DOCUMENT 81A ' S 07/08/66 AUTHOR.- DON ADDRESSEE! RONE VK COPYEE: DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 815 V ^ 0 6 / 2 2 / 6 6 ALLEN AF RONE VK TYPE PAGES LETTER UNIV OF PA DON TITLE PAGE TIME SCHEDULE FOR PROGRESS REPORT ON ACNEOENS STUDY CTTL. 118 LETTER DON UNIV OF PA INVITATION TO PRESENT ON NORK DONE WITH ACNEGENS CTTL. LETTER KLIGMAN AM 1 COVERLETTER FOR SUPPLEMENTING DATA SUBMITTED BY DR KlIGMAN ON TCDD STUDY CTTL. UNIV OF PA ALLEN AF LETTER KLIGMAN DON / 1^ CONCERNS DATA COLLECTED IN STUDY CTTL. UNIV OF PA DOCUMENT AUTHOR: ADDRESSEE! COPYEE: 816 05/31/66 KLIGMAN AM RONE VK S DOCUMENT 817 ' S 07/09/65 LETTER UNIV OF PA DON LETTER AUTHOR! DON ADDRESSEE: HOSPITAL OF THE UNIVf OF COPYEE: DON HOYLE HR RONE VK KLIGMAN AM RONE VK KRAMER DOCUMENT 818 ' S 07/08/65 AUTHOR: ADDRESSEE* COPYEE: DOCUMENT AUTHOR: ADDRESSEE: COPYEE: DON y/ 819 KLIGMAN DON 01/23/68 AM REPORT RONE VK LETTER UNIV OF PA RONE VK TCDD STUDY CTTL. 2 \S COMMUNICATION ON SUGGESTED PROTOCOL FOR TCDD STUDIES ON HUMAN SUBJECTS CTTL. GORDON HL PETERSON JE HOLDER BB SILVERSTEIN L DIBENZO-P-DIOXIN 2378-TETRACHL0R0 REQUEST FOR SCREENING OR APPLICATION TESTING. 2 / RECAP OF KLIGMAN TESTS OF TCDD ON HUMAN SUBJECTS CTTL. 90 o NUMBER / DATE TYPE PAGES / TITLE PAGE 119 DOCUMENT 820 ^ 00/00/65 AUTHOR* ADDRESSEE* COPYEE* NIELSEN K UNIV OF COPENHAGEN / NEWS REPORT KAEMPE B H i/ FATAL POISONING IN MAN BY 24D DETERMINATION OF THE AGENT IN FORENSIC MATERIALS (ACTA PHARMACOL ET TOX 22, 229-234). JENSENHOLM J UNIV OF AARHUS DOCUMENT AUTHOR* ADDRESSEE* COPYEE* 821 ^ 00/00/00 LEGAL X 3 WEED SCIENCE SOCIETY OF AMERICA PROPOSED RESOLUTION NO.l EPA ACTION REGARDING RESGISTRATION CANCELLATION HEARINGS ON 245T AND SILVEX. ADMINISTRATOR AG MARKETI CHAIRMAN HOUSE APPROPRIA DEPUTY DIRECTOR SEA CR DIRECTOR SEA PRESIDENT AM SEED TRADE / ADMINISTRATOR APHIS CHAIRMAN SENATE AG8F0RES DEPUTY DIRECTOR SEA E EMBASSIES OF COUNTRIES M SECRETARY AG / ADMINISTRATOR VET ADMIN CHAIRMAN SENATE APPROPRI DIRECTOR OF EACH ST DEPT EPA STUART EIZENSTAT PRESIDE CHAIRMAN HOUSE AG COMM DEPUTY DIRECTOR SEA AR DIRECTOR OFFICE MANAGEME PLANT INDUSTRY COMM NATL DOCUMENT AUTHOR* ADDRESSEE* COPYEE* 822 ^ 08/16/78 CROSBY DG BLAIR EH DOCUMENT AUTHOR* ADDRESSEE* COPYEE* / 823 10/13/82 HEINE M LETTER UC DAVIS DOW 1^ NEWS 1v TUSCALOOSA NEWS HERBICIDE NOT LINKED TO BOY'S DEATH (TUSCALOOSA NEHS). DOCUMENT 824 ^ 10/20/82 AUTHOR* M O R G A N PE II ADDRESSEE* MCDUFFIE JR COPYEE* BLOCH JA REPORT 3 DEPT OF AG & IND AL DEPT OF AG 8 IND AL VANPRUITT RANDALL CEPHUS SAMPLES (R17038, R17039, R17040) (PRELIMINARY REPORT 821014KFINAL REPORT 821014). AUBURN UNIV DOCUMENT AUTHOR* ADDRESSEE* COPYEE* 825 x/ 00/00/00 MEMO 1*/ RIGHT-OF-WAY MAINTENANCE. DOCUMENT 826 12/22/82 AUTHOR* BLOCH JA ADDRESSEE* CEPHUS C COPYEE* HAGOOD J LETTER 8 REPORT DEPT AG 8 IND AL HARE FH EVERGREEN HELICOPTER M O R G A N P E II HARE WYNN NEWELL 8 NEWTO cn NUMBER DOCUMENT 827 DATE 07/20/82 AUTHOR: SANTINA HD ADDRESSEE: COPYEE: DOCUMENT AUTHOR: ADDRESSEE: COPYEE: '/ 828 08/12/82 HEINE M DOCUMENT 03/11/83 AUTHOR: AL POWER ADDRESSEE: COPYEE: DOCUMENT 830 04/00/79 AUTHOR: N CNTL FOR EX S ADDRESSEE COPYEE: SORENSEN RW DOCUMENT 831 AUTHOR: DOW ADDRESSEE COPYEE: 09/24/79 DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 832 DOW ~ 04/00/66 DOCUMENT 833 V 05/00/70 AUTHOR: DOW ADDRESSEE' COPYEE: MCINTYRE HH DOCUMENT 834 \X 06/01/78 AUTHOR: DOW ADDRESSEE: COPYEE: TYPE PAGES /TITLE -X ----------- PAGE 120 REPORT 3 VX POSTMORTEM EXAMINATION (CASE 27(A)-82-4573A RANDALL CEPHUS, SUBJECT A-82-56). DEPT OF FORENSIC SCIENCE NEWS 1^ TUSCALOOSA NEWS TESTS FIND NO TRACE OF TORDON (TUSCALOOSA NEWS). NEWS 2\X 60 MINUTES TO AIR SEGMENT CONCERNING AL POHER (UPDATE). NEWS PERALA DA V ' CREATING STABLE SHRUB COMMUNITIES FOR MANAGED OPENINGS IN THE ASPEN FOREST (DTE 35(2)19-24, 1979). TECH 3 TORDON (R) 101 MIXTURE WEED AND BRUSH KILLER (87120) (MATERIAL SAFETY DATA SHEET). LABEL TORDON 101 MIXTURE. LABEL 2'X TORDON 101 MIXTURE WEED AND BRUSH KILLER. TECH TORDON (R) 101 MIXTURE WEED AND BRUSH KILLER MATERIAL SAFETY DATA SHEET. -e\tb'(L oe HUMBER DOCUMENT 835 AUTHOR: DOW ADDRESSEE COPYEE: DATE 04/25/79 DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 836 \/ DOW 08/00/79 , DOCUMENT AUTHOR: ADDRESSEE COPYEE: 837 DOW 01/00/80 DOCUMENT 838 10/00/74 AUTHOR: DOW ADDRESSEE: COPYEE: JOHNSON RR / DOCUMENT 839 \ J 12/00/65 AUTHOR: DOW ADDRESSEE COPYEE: DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 840 \/ DOW 02/00/78 DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 841 ^ DOW 07/00/64 DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 842 ^ DOW 08/00/75 TYPE PRINT TECH PAGES 3 flTLE T O R D O N 101 M I X T U R E W E E D 8 B RUSH K I L L E R MSD 0381. PAGE 121 LABEL Z \/ DOW TORDON 101 MIXTURE WEED AND BRUSH KILLER. LABEL 2 V TORDON 101 MIXTURE HEED AND BRUSH KILLER. LABEL SPEER L LABEL LEGIS 2^ TORDON 101 MIXTURE WEED AND BRUSH KILLER (86-1160, EPA REG. 464-306AA). TOWNSEND R WRIGHT H 1 % TORDON 101 MIXTURE BRUSH KILLER (PA2.14.S1). LABEL 4 1 TORDON 101 MIXTURE WEED AND BRUSH KILLER. LABEL 2^ TORDON 101 MIXTURE BRUSH KILLER. LABEL 2 ^ TORDON 101 MIXTURE WEED AND BRUSH KILLER. NUMBER / DATE DOCUMENT 843 V AUTHOR: DOW ADDRESSEE COPYEE: 10/00/78 DOCUMENT 844 \/ 07/14/76 AUTHOR: TOWNSEND RM ADDRESSEE' HOLZSCHU RG COPYEE: HEIN ND FLANNERY RF / DOCUMENT 845 ^ 00/00/76 AUTHOR' LICHY CT ADDRESSEE' COPYEE: DOCUMENT 846^ 09/12/80 AUTHOR: BELLEW RE REIMER CA ADDRESSEE DOW COPYEE: y DOCUMENT 847 10/31/79 AUTHOR' DOW ADDRESSEE' COPYEE: y' DOCUMENT 848 x f 04/23/79 AUTHOR' DOW ADDRESSEE' COPYEE: DOW TOWNSEND RM DOCUMENT 849 \/ 04/23/76 AUTHOR! DOW ADDRESSEE' COPYEE' DOW TOWNSEND RM TYPE LABEL PAGES LABEL LETTER DOW STRINGER WM 1^ NEWS DOW 7^ MEMO REPORT CHADDOCK JD NILSEN A zy REPORT io y MAZEROLLE M REPORT FINK R COULTER LL WRIGHT WG REPORT FINK R COULTER LL WRIGHT WG 8^ */ 4118 ) TITLE TORDON 101 MIXTURE PAGE 122 AMCHEM 245T LABEL TO INCREASE TORDON 101. WRIGHT WG NEITZKE ET BRUSH CONTROL WITH GARLON HERBICIDES ALONE & IN COMBINATION WITH TORDON 101 MIXTURE OR 24D HERBICIDES USING TREE METHODS OF APPLICATION (INDUSTRIAL VEGETATION MANAGEMENT 10 (2), 5-11). GARLON 3A AND TORDON 101. DOW MCLEOD DM PICLORAM RESIDUE DETERMINATIONS AFTER TORDON 101 APPLICATION FOR BRUSH CONTROL 770000 R t D REPORT CS 575 GHS-C-5 CRI 801491. STEHL RH SUBACUTE DIETARY TOXICITY STUDY OF TORDON 101 MIXTURE ON THE MALLARD CRI 76 3397 LABORATORY REPORT CODE GH-RC 68. KENAGA EE WILDLIFE RES DIV MD MCCOLLISTER DD STRINGER WM SUBACUTE DIETARY TOXICITY STUDY OF TORDON 101 MIXTURE ON THE BOBWHITE CRI 76 3396 LABORATORY REPORT GH-RC 69. KENAGA EE MCCOLLISTER DD STRINGER WM NUMBER DOCUMENT 850 ^ DATE 02/24/78 AUTHOR ADDRESSEES COPYEE KRAUSE RE SEYMOUR KG DISHBURGER GORING CA JANTZ OK MINTZ MJ PARSEY ES REYES JO WINEGERTER HJ LE DOCUMENT 11/14/77 AUTHOR ADDRESSEE COPYEEs DOM DOW COLBY RW DREYER WA GRUMBLES JB HEFNER RE HYMAS TA MCCOLLISTER REGAN JB TURNER GO DD DOCUMENT AUTHOR DOW ADDRESSEE: COPYEE: DOM 02/25/77 DOCUMENT 853 y 09/07/76 AUTHOR' DOM LOEHNE E ADDRESSEE COPYEE: DOW / DOCUMENT AUTHOR: ADDRESSEE: COPYE^ 854 ' 08/12/75 C H A S E FI MANFROM R TOWNSEND RM FRASER JM M C L A U G H L I N EL WOODS CD TYPE PAGES ABSTRACT REPORT SEYMOUR KG 10 V BJORK CK DONALDS JE HANSON RG KOHLBRAND HT MITCHELL MK PLAUMANN D SAUNDERS ES REPORT JANTZ OK JANTZ OK C O U L T E R LL FERGUSON RH HAAGSMA TA HOLMSEN TW LANING ER MOSS RD RITTY PM VANDERSCHAAF P REPORT FRASER JM REPORT LAFEVOR D RUZZALA R FRASER JM / SPEC FRASER JM M C L A U G H L I N EL WOODS CD HOFF RC SEYMOUR KG / TITLE PAGE 123 TORDON 101 MIXTURE CANDIDATE FORMULATION H-S779 THO YEAR STORAGE STABILITY DATA (RAD REPORT)(CH-C 1 0 8 5 H C R I 781591). BOHNERT T F U R C H E S BJ HEFNER RE LACEY R MOSS RD PRUITT ME V A N H O R N RL C O U L T E R LL GOLD MI HYMAS TA MCCOLLISTER OSBORNE DM RANCE RR VOGEL AJ DD HIGH VOLUME APPLICATIONS OF TRICLOPYR APPLIED ALONE AND HITH OTHER HERBICIDE PRODUCTS FOR MOODY PLANT CONTROL IN MN IN 760000 (R 8 D REPORT M G H - P l 016). RYDER JC BTORK CK DISHBURGER HJ GERONIMO J HANSON RG HUNTER JH LICHY CT OSBORNE DM SAUNDERS ES MARREN LE BYRD BC DONALDS JE GORING CA HEBBOURN RG HUNTER RC LUDMIG PD PRUITT ME SEYMOUR KG MILLIAMS CS TORDON 101 MIXTURE (AGRICULTURAL CHEMICALS TECHNOLOGY CENTER ILU TEST PROGRAM). ANALYSIS OF TECHNICAL PICLORAM AND TORDON 101 FOR ILU TEST PROGRAM (ANALYTICAL REPORTKAL 76-40370). LAMKIN R LANGE C ZIMMERMAN R TORDON 101 MIXTURE M-3296 (PRODUCTION SPECIFICATION). HOFF RC HOLDEMAN GE SEYMOUR KG STRINGER MM HOLDEMAN GE STRINGER MM MANFROM R TOWNSEND RM NUMBER DOCUMENT 855 AUTHOR DOW ADDRESSEE: COPYEE: DATE 09/24/79 /D O C UMENT 856 07/02/79 AUTHOR: ADDRESSEE COPYEE: DOCUMENT AUTHOR: ADDRESSEE COPYEE BUZZELLI DT DRENCKPOHL JW SEMANCO J y 857 08/10/80 CHENOWETH MB DOCUMENT AUTHOR: ADDRESSEE COPYEE: 858 DOW 11/00/74 DOCUMENT 859 AUTHOR: DOW ADDRESSEE: COPYEE: 03/00/74 DOCUMENT 860 AUTHOR DOW ADDRESSEE: COPYEE: 03/00/74 DOCUMENT 861 ^ 07/22/76 AUTHOR: ADDRESSEE COPYEE: DOW STRINGER WM TOWNSEND RM KEENEY FN 'O \ -C. O TO O TYPE TECH PAGES -- --y TITLE PAOE 124 TORDON 101 MIXTURE WEED AND BRUSH KILLER MATERIAL SAFETY DATA SHEET (TRANSPORTATION EMERGENCY MANUAL). SPEC COLBY RH FRASER JM STRINGER WM y TORDON 101 MIXTURE HEED AND BRUSH KILLER (QUALITY ASSURANCE PRODUCTION SPECIFICATION). DEI BEL C DOW GOLD WL SCOLES GW VANHORN R WOODS CD TECH DOW TORDON 101 (MEDICAL INFORMATION). KEELER P LABEL TORDON 101 MIXTURE HEED AND BRUSH KILLER. TECH 2 > TORDON 101 MIXTURE WEED AND BRUSH KILLER (MATERIAL SAFETY DATA SHEET). TECH 2 TORDON 101 MIXTURE WEED AND BRUSH KILLER (MATERIAL SAFETY DATA SHEET). LETTER VANH O R N RL DOW WRIGHT WG 2 ^ DATE REQUIREMENTS EPA APPLICATIONS TORDON 202, TORDON 101 MIXTURE, TORDON 22K, TORDON 10K AND TORDON 5K. DOW HOLDEMAN GE NUMBER / ' date DOCUMENT 862 ^ 06/04/76 AUTHOR: DOM ADDRESSEE- DOM COPYEE: DOM DOCUMENT / 863 {/ 10/22/76 AUTHOR: ADDRESSEE COPYEE: DOM DOM GERONIMO J HEFNER RE MOSS RD SAUNDERS ES MILLIAMS CS DOCUMENT 86A ^ AUTHOR: DOM ADDRESSEE COPYEE: 10/20/76 DOCUMENT 865 05/19/76 AUTHOR: ADDRESSEE: COPYEE: DOM DOM FEARS RD HANSON RG MOSS RD SAUNDERS ES DOCUMENT 866 ^ ^ 0 8 / 0 4 / 7 5 AUTHOR: ADDRESSEE: COPYEE: DOM MILLIAMS CS DOM GERONIMO J LANINO ER REGAN JB DOCUMENT AUTHOR: ADDRESSEE: CDPYEE: 867 '///^ 0 1 / 1 8 / 7 0 DOM H-*to TYPE PAGES LETTER 1r ^ ` KRAUSE RE V A N H O R N RL KEENEY FN REPORT 13 FEARS RD FEARS RD GORING CA HOLMSEN TM REGAN JB S MITH LL MRIGHT MG REPORT FEARS RD 15 REPORT MARREN LE MARREN LE GERONIMO J HEFNER RE REGAN JB MRIGHT MG 19 REPORT 15 FEARS RD FEARS RD HANSON RG MCCOLLISTER DD SHAV ER RJ REPORT HEIN ND 14 TITLE PAGE 125 STATUS OF STUDIES ON TORDON 101 AND TORDON 22K FORMULATED WITH REDUCED ALCOHOL CONTENT. EVALUATION OF TORDON 101 MIXTURE AND ESTERON 245 TANK MIXTURES A P P L I E D FOR FOREST SI T E P R E P A R A T I O N N E A R DAYTON, T E N N E S S E E IN' 710000 (770059). FREDERICK DM BYRD BC GRUMBLES JB LICHY CT RITTY PM STRINGER WM COLBY RW HANSON RG MCCOLLISTER RYDER JC WARREN LE DD PERFORMANCE OF GARLON 3A HERBICIDE THROUGH AERIAL APPLICATION ON A RIGHTOFWAY NEAT TUSCALOOSA AL (LAB REPORT GH-P1005, 771652). FREDERICK DM CONTROL OF WOODY PLANTS WITH LEAF STEM SPRAYS OF TRICLOPYR (REPORT GH-P 968) (769134). WILLIAMS CS WILLIAMS CS GORING CA LINCE M RITTY PM BYRD BC GRUMBLES JB MCCOLLISTER DD RYDER JC EVALUATION OF DOWCO 233 AND TORDON 101 MIXTURE ESTERON 245 TANK MIXES AS HIGH VOLUME SPRAYS ON INDIVIDUAL HOODY PLANTS IN GA (REPORT G H - P - 9 2 2 H 756839). FREDERICK DM HAAGSMA TA WILLIAMS CS HEFNER RE MOSS RD SIMON C FERGUSON RH JANTZ OK OSBORNE DW S M I T H LL CHEMICAL SITE PREPARATION FOR PINE (REPORT B-15459). NATION HA HUMBER / D A T E DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 868 ^ DOW 03/13/78 DOCUMENT AUTHOR: ADDRESSEE: COPYEE: DOCUMENT AUTHOR: ADDRESSEE: COPYEE: V869 11/30/71 DOW y 870 03/00/74 DOW DOCUMENT AUTHOR: ADDRESSEE: C O P Y E E4: DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 871 DOW 872 DOW 03/00/74 \fy ` 03/28/72 DOCUMENT /873 03/00/74 AUTHOR: DOW A D D R E S S E E '- COPYEE: DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 874 DOW '^03/28/72 DOCUMENT AUTHOR: ADDRESSEE: COPYEE' 875 DOW \ 01/28/76 DOCUMENT AUTHOR: ADDRESSEE: COPYEE' y876 DOW 09/00/76 TYPE REPORT MERY C PAGES /TITLE PAGE 126 2 I/** WEED CONTROL IN IRRIGATED SUGARCANE HITH TORDON 101 (ROI 68185). TECH 5 TORDON 101 MIXTURE MATERIAL SAFETY DATA SHEET. TECH 4 TORDON 101 MIXTURE MATERIAL SAFETY DATA SHEET. TECH 2 ^ TORDON 101 MIXTURE WEED AND BRUSH KILLER MATERIAL SAFETY DATA SHEET. TECH 2' TORDON 101 MIXTURE MATERIAL SAFETY DATA SHEET. TECH 2*'' TORDON 101 MIXTURE WEED AND BRUSH KILLER (MATERIAL SAFETY DATA SHEET). TECH 2 V TORDON 101 MIXTURE (MATERIAL SAFETY DATA SHEET). PROC HIGHHILL CA 1 HANDLING TORDON 101 SPILLS. LABEL 2 TORDON 101 MIXTURE WEED AND BRUSH KILLER (EPA SLN CA-760183). V NUMBER DATE DOCUMENT 877 - y - 09/00/76 AUTHOR: DOM ADDRESSEE COPYEE: DISTR AT DOM0936401 TYPE LABEL PAGES DOCUMENT 878 / 09/00/76 AUTHOR: DOW ADDRESSEE COPYEE: DISTR AT D0W0936401 LETTER MARREN LE 1 y TITLE PAGE 127 T0RD0N 101 MIXTURE MEED AND BRUSH KILLER (EPA SLN CA-760183). TORDON 101 MIXTURE FOR USE IN CALIFORNIA FOREST INDUSTRY. DOCUMENT 879 V AUTHOR: DOW ADDRESSEE: COPYEE: 06/14/79 REPORT 7 1 TORDON 101 SUMMARY OF EFFICACY DATA AGRICULTURAL CHEMICALS R D INFORMATION ASSEMBLY. DOCUMENT AUTHOR: ADDRESSEE: COPYEE- 880 V 07/27/77 DOM DOM MACQUILLAN MJ DOM MCCOLLISTER DD WRIGHT MG DOCUMENT AUTHOR: ADDRESSEE COPYEE: 881 V / " 08/25/76 CHADDOCK J DOM SEYMOUR KG TELEX 1 GETZENDANER ME BROWN FG C O U L T E R LL SMITH JT TORDON 101 FORMULATION CHANGE. HEBBOURN DG LANING ER DRENCKPOHL JH STRINGER MM KEENEY FN MOODS CD REPORT DOM HIGHHILL CA SPEER LH 6 I.'-' F O A M I N G C H A R A C T E R I S T I C S OF P R O P O S E D T O R D O N 101 F O R M U L A T I O N (M-3779 REIMER CA VANHORN RL KEENEY NF WRIGHT MG MANFROM RP DOCUMENT 882 v / ^ 01/06/75 AUTHOR ADDRESSEE COPYEE: DOM DOM MCCOY CE TOWNSEND RM REPORT VA N H O R N RL C H A S E FI PARSEY ES 10 EFFECTS OF POLYGLYCOL 26-2 AND VERSENE ON TORDON ICI MIXTURE HATER DILUTIONS (INTERIM REPORT 163). HOFF RC SEYMOUR KG KEENEY FN SOUTHMICK L DOCUMENT 883 / 06/11/71 AUTHOR: ADDRESSEE COPYEE: DOM DOM KENAGA EE ROC HIFFEN EE C O U L T E R LL LENG ML 2 EFFECT OF TORDON 101, DDT, ESTERON 3-3E ON HATCHABILITY OF POULTRY EGGS. HAAGSMA TA LYNN GE HEBBOURN RG MCCOLLISTER DD CO NUMBER y DATE DOCUMENT 884V 06/00/75 TYPE REPORT PAGES 11 AUTHOR: HEITMULLER T ADDRESSEES COPYEEs ABCT CORAL GABLES DOW TOWNSEND RM MARINE RES LAB ABCT HONG KONG MCCOLLISTER DD TITLE PAGE 128 ACUTE TOXICITY OF TORDON 101 MIXTURE TO LARVAE OF THE EASTERN OYSTER (CRASSOSTREA VIRGINICA) PINK SHRIMP (PENAEUS DUORARUM) AND FIDDLER CRABS (UCA PUGILATOR). PARRISH R ABCT KINGS LYNN SOUTHWICK L ABCT SARNIA STRINGER HM DOCUMENT 885 f 02/09/71 AUTHORS DOW ADDRESSEES DOW COPYEEs DOW MURPHY AR DOCUMENT AUTHOR: ADDRESSEES COPYEEs / 886 ** DOW 12/00/78 DOCUMENT 887 ^ 03/09/70 AUTHORS BJERKE EL WILLIAMS CS ADDRESSEE COPYEEs MOSS RD GORING CA DOCUMENT 888 ' S 03/07/75 AUTHORS FINK R ADDRESSEE DOW COPYEEs DOW TOWNSEND RM LETTER GORING CA CAMPBELL BL FERGUSON RH RITTY PM 3 LABEL 3 DEGRADATION OF HERBICIDES IN THE FOREST FLOOR, LOGAN A NORRIS. HAMAKER JW HARREN LE HOHE RG TORDON 101 MIXTURE HEED AND BRUSH KILLER. SPECIMEN LABEL. REPORT BYRD BC y 61 A STUDY OF POTENTIAL MOVEMENT OF PICLORAM AFTER APPLICATION TO HIGHWAY AND RAILROAD RIGHTSOFWAY(GH-C 379). GETZENDANER ME MOSS RD WILLIAMS CS LENG ML BARRONS KC LUDWIG PD CAMPBELL B RIDNER JM REPORT /9 EIGHT DAY DIETARY LC50 BOBNHITE QUAIL TORDON 101 MIXTURE FINAL REPORT (PROJECT NO. 103-133). TRUSLOW FARMS COULTER LL WRIGHT HG MCCOLLISTER DD STRINGER HM DOCUMENT 889 04/23/76 REPORT 1 y SUBACUTE DIETARY TOXICITY STUDY OF TORDON 101 MIXTURE ON THE BOBMHITE (GH-RC 69). AUTHOR: DOH FINK R KENAGA EE TRUSLOH FARMS ADDRESSEE: COPYEEs DOH COULTER LL MCCOLLISTER DD STRINGER HM TOWNSEND RM WRIGHT WG DOCUMENT 890 ^ 03/07/75 AUTHOR FINK R ADDRESSEE: DOW COPYEEs DOW TOWNSEND RM REPORT 9v / TRUSLOW FARMS COULTER LL WRIGHT WG EIGHT DAY DIETARY LC50 MALLARD DUCKS TORDON 101 MIXTURE FINAL REPORT (PROJECT NO. 103-134). MCCOLLISTER DD STRINGER HM HUMBER DATE DOCUMENT 891^ 05/16/75 AUTHOR: DOW ADDRESSEE COPYEE: DOM DISHBURGER HJ HUDSON T LITTLE J NEWPORT J SEYMOUR K TOWNSEND RM y DOCUMENT 892 05/07/75 AUTHOR! FINK R ADDRESSEE DOM COPYEE: DOCUMENT 893 10/22/76 AUTHOR: DOW ADDRESSEE: COPYEE: DOCUMENT 899 V/ 01/03/77 AUTHOR: DOM ADDRESSEE: COPYEE: DOCUMENT 895 AUTHOR: DOM ADDRESSEE: COPYEE: 08/12/75 DOCUMENT 896 07/02/79 AUTHOR: ADDRESSEE: COPYEE: BUZZELLI DT FRASER JM MOODS CD TYPE PAGES / TITLE PAGE 129 REPORT HOMARD AJ 10 QUANTITATIVE DETERMINATION OF N" (3956-TETRACHL0R0-2-PYRIDYL) GUANIDINE IN TORDON HERBICIDE FORMULATIONS (ML-AL75-00695). SKELLY NE CAREY F FRANCOIS C KENAGA EE MANFROM R PARROT A SHEETZ DP WILLIAMS CS CHASE F GORING CA LACOUME J MCCOLLISTER DD PARSEY ES STONE F WOODWARD R CRUMMETT WB HOLDEMAN G LASKOMSKI D MOSS RD SEXTON A STRINGER HM YEAMAN D REPORT 7v/ TRUSLOW FARMS EIGHT DAY DIETARY LC50 BOBHHITE QUAIL TORDON 101 MIXTURE FINAL REPORT PROJECT NO. 103 133. REPORT FEARS RD 13 EVALUATION OF TORDON 101 MIXTURE AND ESTERON 295 TANK MIXTURES APPLIED FOR FOREST SITE PREPARATION NEAR DAYTON, TN IN 710000 (LAB REPORT GH-P 991). FREDERICK DM REPORT FEARS RD EVALUATION OF TORDON 101 MIXTURE AND ESTERON 295 TANK MIXTURES APPLIED FOR FOREST SITE PREPARATION NEAR DAYTON TN IN 710000 (LAB REPORT GH-P 991). FREDERICK DM WRIGHT HG SPEC TORDON 101 MIXTURE HEED AND BRUSH KILLER SALES SPECIFICATION. PRINT SPEC COLBY RH SCOLES GM 3 / TORDON 101 MIXTURE MEED AND BRUSH KILLER DOW QUALITY ASSURANCE PRODUCTION SPECIFICATION (TRANSPORTATION EMERGENCY MANUAL). DOM SEMANCO J DRENCKPOHL JW STRINGER MM NUMBER / DATE DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 897 ^ DOW 09/19/79 DOCUMENT AUTHOR: ADDRESSEE COPYEE: 98 DOW 11/21/7* DOCUMENT 899 ^ 11/19/79 AUTHOR B J E R K E EL ADDRESSEE: COPYEE: DOCUMENT 900 11/19/79 AUTHOR: B J E R K E EL ADDRESSEE: COPYEE: DOCUMENT AUTHOR: ADDRESSEE COPYEE: 901 ' S ' 38/10/80 CHENOWETH MB DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 902 08/10/80 CHENOWETH MB DOCUMENT 903 ^ AUTHOR: DOW ADDRESSEE: COPYEE: 11/19/73 DOCUMENT 909 AUTHOR: DOW ADDRESSEE: COPYEE: DOW 09/20/71 TYPE LABEL PAGES 5 LABEL REPORT DOW 17 ^ REPORT DOW 1^ TECH DOW 2 t-""' TECH DOW 2^ TECH SKELLY NE 7^ SPEC 1^ BASINGER RF TITLE TORDON 101 MIXTURE PROPOSED LABEL COPY PAGE 130 LABEL COPY TORDON 101 MIXTURE HEED AND BRUSH KILLER. RESIDUES OF PICLORAM AND 24D IN GRASS FOLLOWING TREATMENT WITH TORDON 101 MIXTURE IN PUERTO RICO (RAD REPORTMGH-C 769). RESIDUES OF PICLORAM AND 24D IN GRASS FOLLOWING TREATMENT HITH TORDON 101 MIXTURE IN PR (RAD REPORT). MOSS RD TORDON 101 R (MEDICAL INF0RMATIONHM-A086). KEELER P TORDON 101 (MEDICAL INFORMATION). KEELER P ANALYSIS OF TORDON 101 HERBICIDE BY LIQUID CHROMATOGRAPHY (ANALYTICAL METHODH87120B) . TORDON 101 MIXTURE DRUM SPECIFICATIONS. HOLDEMAN GE WINTERGER LE NUMBER / D A T E DOCUMENT AUTHOR: ADDRESSEE COPYEE < 905 ^ DOM 08/13/75 DOM MILKS MN DOCUMENT AUTHOR-ADDRESSEE COPYEE: 906 ^ DOM 08/13/75 DOM MILKS HN DOCUMENT 907 v 06/01/77 AUTHOR! ADDRESSEE: COPYEE: DOM DOM HINGERTER LE DOCUMENT AUTHOR: ADDRESSEE COPYEE: 908L DON 08/13/75 DOM MILKS MN DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 909 '* DOM 08/13/75 DOM MILKS MN DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 910 V / 11/29/79 DOM DOM SIAS DM DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 911 DOM 03/19/7 6 DOM HOLDEMAN GE TYPE SPEC PAGES 1 v/ BROMN RC NIELSEN RC SPEC 1` BROMN RC NIELSEN RC SPEC 1! DRENCKPOHL JM SPEC BROMN LG NIELSEN RC 1t SPEC ll ''' BROMN LG NIELSEN RC SPEC 1 V- DRENCKPOHL JM W I N G E R T E R 1LE SPEC BROMN LG SIAS DM 1 ___" JJ fv> u -a TITLE 1 TORDOH 101 MIXTURE DRUM SPECIFICATIONS. HOFF RC HOLDEMAN GE PAGE 131 TORDON 101 MIXTURE PAIL SPECIFICATIONS. HOFF RC HOLDEMAN GE TORDON 101, TORDON 155, TORDON 472, TORDON 101R, TORDON 212, TORDON 2696 PAIL SPECIFICATIONS. GOLD HL SIAS DM TORDON 101 (PORTUGUESE) DRUM SPECIFICATIONS. HOFF RC HOLDEMAN GE TORDON 101 MIXTURE SPANISH DRUM SPECIFICATIONS. HOFF RC HOLDEMAN GE TORDON 101 MIXTURE HEED KILLER DAIL SPECIFICATIONS. GLASER J GOLD HL TORDON 101 MIXTURE (CAN) DRUM SPECIFICATIONS. DIGNARD G DILLEY RH /-.TTYA-^f NUMBER DATE DOCUMENT 912 04/1A/78 AUTHOR: DON ADDRESSEE COPYEE: DON SIAS DM DOCUMENT 913 11/29/79 AUTHOR: DON ADDRESSEE: COPYEE: DON SIAS DM DOCUMENT 91A'/^ 10/01/77 AUTHOR: DON ADDRESSEE: COPYEE: DOCUMENT 915 AUTHOR DON ADDRESSEE: COPYEE: 12/00/76 DOCUMENT 916 V / 02/22/78 AUTHOR: SMITH DN ADDRESSEE COPYEE: DOCUMENT 917 V ^ 05/03/76 AUTHOR: NEHTON M ADDRESSEE COPYEE: DOCUMENT 918 05/03/76 AUTHOR: ADDRESSEE: COPYEE: DOW te so si to GO TYPE SPEC PAGES 1^ DRENCKPOHL JN NINGERTER LE SPEC DRENCKPOHL JN NINGERTER LE PRINT TECH 3, TITLE TORDON 101 MIXTURE HERBICIDE DRUM SPECIFICATIONS. GLASER J GOLD HL PAGE 132 TORDON 101 MIXTURE HERBICIDE DRUM SPECIFICATIONS. GLASER J GOLD HL TORDON 101 MIXTURE HEED AND BRUSH KILLER (MATERIAL SAFETY DATA SHEET) (PHENOXIF.S) (HERBICIDES MATERIAL SAFETY DATA SHEET). REPORT DETERMINATION OF PICLORAM AND 24D CONTENT OF TORDON 101, 1 M39A3(TENTATIVE ANALYTICAL METHOD). REPORT SFFLING R REPORT THE EFFECT OF TORDON 101 HERBICIDE ON SOIL ORGANIC MATTER BALANCEiCAN J BOT 57, 108-115). UNIV OF GUELPH CAN UNIV OF HATERLOO CAN INFLUENCE OF SEASON AND DOSAGE ON EFFECTIVENESS OF INJECTIONS FOR CONTROL OF DOUGLAS FIR (REPRINT FROM RESEARCH PROGRESS REPORT HESTERN WEED CONTROL CONFERENCE RENO, NV 660316 TO 660318)(TECHNICAL DATA 1HTECHNICAL INFORMATION IN SUPPORT OF APPLICATION FOR STATE REGISTRATION OF TORDON 101 MIXTURE HEED AND BRUSH KILLER TO MEET A SPECIAL LOCAL NEED IN I D H P A 2 .08.02.S3) . REPORT 3 i,,,.- TECHNICAL INFORMATION IN SUPPORT OF APPLICATION FOR STATE REGISTRATION OF TORDON 101 MIXTURE WEED AND BRUSH KILLER TO MEET A SPECIAL LOCAL NEED IN OR ( P A 2 .08.02.S3 TORDON 101 STATE REGISTRATION OR 760503). NUMBER / DATE DOCUMENT 919 ^ 05/03/76 TYPE REPORT AUTHOR DOH ADDRESSEE: COPYEE: y/ DOCUMENT 920 ' S 01/16/70 REPORT AUTHOR! DOH ADDRESSEE! COPYEE: / DOCUMENT 921 S AUTHOR: DOW ADDRESSEE! COPYEE: 01/00/70 DOCUMENT 922 01/16/70 LABEL REPORT AUTHOR! DOW ADDRESSEE: COPYEE: DOCUMENT 923 ^ 03/00/78 AUTHOR! DOW ADDRESSEE' COPYEE: DOCUMENT 924 AUTHOR: DOW ADDRESSEE' COPYEE: 11/00/79 DOCUMENT 925 ^ AUTHOR: ADDRESSEE: COPYEE: 9-> VT\ DOW DOW kps H"1 to CO 05/04/70 LABEL TECH LEGIS HAMMER HAMMER PAGES 3 TITLE PAGE 133 TECHNICAL INFORMATION IN SUPPORT OF APPLICATION FOR STATE REGISTRATION OF TORDON 101 MIXTURE HEED AND BRUSH KILLER TO MEET A SPECIAL LOCAL NEED IN ID CPA2.08.02.S2 TORDON 101 STATE REGISTRATION ID 760503). 10 t/ TECHNICAL INFORMATION IN SUPPORT OF APPLICATION FOR REGISTRATION OF REVISED LABELING FOR THE USE OF TORDON 101 MIXTURE HEED AND BRUSH KILLER ON HIGHWAYS, RAILROAD AND UTILITY RIGHTS OF HAY AND OTHER NON CROP AREAS VOLUME 2 CPA.2.08.S10). M 'S LABEL COPY TORDON 101 MIXTURE HEED AND BRUSH KILLER CPA2.08.S9). 7 TECHNICAL INFORMATION IN SUPPORT OF APPLICATION FOR REGISTRATION OF REVISED LABELING FOR THE USE OF TORDON 101 MIXTURE HEED AND BRUSH KILLER ON HIGHWAYS, RAILROAD AND UTILITY RIGHTS OF WAY AND OTHER NON CROP AREAS VOLUME I CPA2.08.S9). TORDON 101 MIXTURE WEED AND BRUSH KILLER FOR DISTRIBUTION AND USE ONLY WITHIN CA, OR AND WA CPA2.08.06 TORDON 101 STATE REGISTRATION OR). 2A'"' TORDON 101 MIXTURE (PRODUCT BULLETINXPA2.08.02 TORDON 101 STATE REGISTRATION CA). 3 ^ TORDON 101 MIXTURE WEED AND BRUSH KILLER(464-306)CAPPLICATION FOR AMENDED REGISTRATION OF ECONOMIC POISONS). USDA NUMBER x. DATE DOCUMENT 926 x/ 05/04/70 AUTHOR: DOW ADDRESSEE DOH COPYEE DOCUMENT AUTHOR: ADDRESSEE COPYEE / 927 V 05/22/70 ALFORD HG DOH y D O C U M E N T 928 l/ 0 5 / 0 4 / 7 0 AUTHOR DOW ADDRESSEE: DOH C O P Y E E ' DOCUMENT AUTHOR: ADDRESSEE COPYEE: 929 ALFORD DOW 05/22/70 HG DOCUMENT 9 Z f ) S 06/03/70 AUTHOR: ALFORD HG ADDRESSEE DOH COPYEE: DOCUMENT 9 3 1 '/ / 06/12/70 AUTHOR: DOW ADDRESSEE: ALFORD HG COPYEE: DOW DOCUMENT 932 08/27/71 TYPE PAGES LEGIS 2 tX HAMMER OH HAMMER OH LETTER USDA ARS 1^ LEGIS HAMMER OH HAMMER OH 2 1/ LETTER USDA 1 1/ LETTER USDA ARS HAMMER OH 1 i/ LABEL LETTER TALCOTT AT USDA ARS HAMMER OH 2 */r" REPORT 13 AUTHOR DOW ADDRESSEE COPYEE DOCUMENT AUTHOR ADDRESSEE COPYEE: 933 DOH HARREN LE 06/00/70 LABEL 1 TITLE PAGE 134 TORDON 101 MIXTURE MEED AND BRUSH KILLERC464-306HAPPLICATION FOR AMENDED REGISTRATION OF ECONOMIC POISONS). USDA y TORDON 101 MIXTURE!USDA REG. 464-306 HYO U R APPLICATION OF 7005I04). TORDON 101 MIXTURE HEED AND BRUSH KILLER(464-306)(APPLICATI0N FOR AMENDED REGISTRATION OF ECONOMIC POISONS). USDA TORDON 101 MIXTURE(USDA REG. 464-306MYOUR APPLICATION OF 700504). TORDON 101 MIXTURE!USDA REG. 464-306HYOUR TELEPHONE CONVERSATION OF 700601). TORDON 101 MIXTURE HEED AND BRUSH KILLER!USDA REGISTRATION 464-306). SUNDERLAND HH CONTROL OF UNDESIRABLE MOODY PLANTS HITH AERIAL SPRAYS CONTAINING NEH INVERT EMULSION FORMULATIONS OF 24D, 245T AND PICLORAM!REFERENCE REPORT B) !TECHNICAL INFORMATION IN SUPPORT OF THE APPLICATION FOR REGISTRATION OF VERTON 2D VERTON 2T AND TORDON K HERBICIDES)!DA14.02.S3 PERFORMANCE). TORDON 101 !DA14.02.S2). NUMBER DATE DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 934 DOW 05/00/79 DOW DISHBURGER HAAGSMA TA HUNTER JH LANINO R MOSS RD VRANISH SR HJ DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 935 DOM 05/09/79 DOCUMENT 936 AUTHOR: DOW ADDRESSEE COPYEE: 03/00/74 DOCUMENT 937 '>""^10/26/79 A u t h o r -- dow ADDRESSEE: COPYEE: DOCUMENT AUTHOR: ADDRESSEE COPYEE 938 ' S DOW DOW DOW 05/16/79 DOCUMENT 939 \ S ' 07/29/77 AUTHOR: DOW ADDRESSEE: DOW COPYEE: DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 940 " S DOW DOW DOW 09/26/78 DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 941 DOW DOW DOW 09/26/78 Sb H-* JO 0 0 TYPE PAGES ABSTRACT PAEZ JA 3^' BRIONES L FERGUSSON H HAMMOND LE HUNTER RC LINCE M PRUITT ME WESELOH JH TITLE TORDON 101 HERBICIDE LAB REPORT NO 79.025.004 CARVALHEIRO FLETCHER DR HANSON RG JANTZ OK MCC0LL1STER SHEETZ DP A DD COULTER LL GORING CA HEBBOURN D LADEIRA A MITCHELL K TURNER GO PAGE 135 TEST 14 V ---T O R D O N 101 M I X T U R E W E E D A N D B R U S H K I L L E R t A N A L Y T I C A L M E T H O D 87120E). TECH 2 U--- T O R D O N 101 M I X T U R E W E E D A N D B R U S H K I L L E R M A T E R I A L S A F E T Y DATA S H EET REPORT FISHBECK HA 2 ^ " ~ TORDON 101 101R MEDICAL INFORMATION. KEELER P MEMO MESTRE S HUMBURG ER LANING ER LETTER WOODS CD MESTRE S 11^ TORDON 101 8 LORSBAN 4E NEW LABELS FOR VENEZUELA. WOODS CD PERUVIAN LABELS. DMA 6 NEED KILLER. STERON 245 CONCENTRATE HERBICIDE. TORDON 101 MIXTURE HERBICIDE. TORDON 472 HERBICIDE LETTER WOODS CD MERY C LANING ER LETTER WOODS CD STEVENS F LANING ER 1 TORDON 101 MIXTURE HERBICIDE. PERUVIAN LABELING. VANWERT JB 1 l TORDON 101 MIXTURE HERBICIDE. BRAZILIAN LABELING. VANWERT JB NUMBER ^ DATE DOCUMENT 942 V 07/14/77 AUTHOR: ADDRESSEE COPYEE DOW DOW DRENCKPOHL JW MCCOLLISTER DD TOWNSEND RM DOCUMENT 9 4 3 ' / AUTHOR DOW ADDRESSEE COPYEEs 04/17/78 DOCUMENT 944 AUTHOR DOW ADDRESSEE COPYEE 09/00/76 D O C U M E N T 945 '>/ / 0 3 / 0 0 / 7 8 AUTHOR DOW ADDRESSEE COPYEE: DOCUMENT 946 l / ^ 09/22/70 AUTHOR DOW ADDRESSEE HEW COPYEE: DOCUMENT 947 * 11/14/75 AUTHOR DOW ADDRESSEE COPYEE: HANSON RO DOCUMENT AUTHOR: ADDRE5SEE COPYEE: * aw 'a r o 948 03/21/72 DOW DOW C O U L T E R LL GENTRY WM JOHNSTON RV LUDWIG PD MOSS RD S A U N D E R S ES TYPE PAGES LETTER 2^ STRINGER WM BOHNERT T GETZENDANER ME SEYMOUR KG VANHORN RL LETTER WOODS CD 1- LABEL 2^ LABEL 2w LETTER WILLIAMS GJ S T E I N F E L D JL 2 ABSTRACT REPORT HOLMSEN TW 6 REPORT JOHNSON TB BAILES R DOWELL PH GORING CA KAGY JF MACKEY J OSBORNE DW THOMPSON C 5[ S TITLE PAGE 136 TORDON 101 MIXTURE HERBICIDE CHANGE IN FORMULATION REDUCED IPA. OUR EPA SUBMISSION OF 760803. COLBY RH JANTZ OK SMITH JT MOODS CD COULTER LL KEENEY FN SPEER LH MRIGHT MG REVISED SPECIMEN LABELS FOR TORDON 101 MIXTURE HEED AND BRUSH KILLER. TORDON 101 MIXTURE HEED AND BRUSH KILLER FOR DISTRIBUTION AND USE ONLY MITHIN CA. TORDON 101 MIXTURE NEED AND BRUSH KILLER FOR DISTRIBUTION AND USE ONLY MITHIN CA, OR AND HA. DOM AND DOD AGREE THAT BASED ON CURRENT KNOHLEDGE TORDON 101 CAN BE SAFELY USED BY THE DOD CTTL. VAPOR PHASE PHYTOTOXICITY OF TORDON 101 HERBICIDE, LOTS 590634, 590905 AND 591135 (GS-1435). VAPOR PHASE PHYTOXICITY DOH PRODUCTS, 9 TORDON 101 MIXTURE. BLAIR EH FERGUSON RH HEITZ R KUYPER CK M A G A N A JL PRUITT ME TURNER GO BREMNER NH G A N T Z RL HYMAS TA LINCE M MCCOLLISTER REGAN JB MRIGHT MG DD NUMBER DATE TYPE PAGES DOCUMENT 949 V 03/21/72 AUTHOR ADDRESSEE COPYEE DOW DOW BLAIR EH FERGUSON RH GORING CA JOHNSON RB LINCE M M A G A N A JL OSBORNE DW SEYMOUR KG WRIGHT WG DOCUMENT 950 c / 06/02/75 AUTHOR ADDRESSEE C0PYEE DOW DOW KEENEY FN DOCUMENT 951 ^ AUTHOR DOW ADDRESSEE COPYEE .03/00/74 DOCUMENT 952 ' S 08/22/78 AUTHOR ADDRESSEE COPYEE COLBY RW COLBY RW BJORK CK DONALDS JE GORING CA HOLMSEN TW JANTZ OK MOSS RD REGAN JB S C H M I D T K E DJ VRANISH SR H "* ;Sj5 CO 1U C O -4) ABSTRACT JOHNSON TB BAILES R BREMNER NW G ANT Z RL HEITZ R JOHNSTON RV LITTLE JC MCCOLLISTER PRUITT ME SHELDON HW 1 l/ REPORT VANHORN RL BYRD BC PARSEY ES TECH 1 v/ 2 i-' DISTRB 48 REPORT DOW DOW BYRD BC DREYER WA G R A H A M DL HUNTER JH LICHY CT NILSEN A RITTY PM SEYMOUR KG WILLIAMS CS TITLE PAGE 137 VAPOR PHASE PHYTOTOXICITY DOW PRODUCTS# 9 TORDOH 101 MIXTURE!1600019). BAURIEDEL HR COULTER LL GENTRY WM HINMAN CH KAGY JF LUDWIG PD MOSS RD REGAN JB THOMPSON C BJORK CK DOWELL PH GETZENDANER ME HYMAS TA KUYPER CK MACKEY J MUELDER NW SAUNDERS BS TURNER GO COMPATIBILITY OF TORDON 101 MIXTURE AND DOHCO 233 (M-3724) NITH KARMEX 80 WP AND PARAQUAT CL AG FORMULATIONS (INTERIM REPORT NO 181) (DATA BOOK 1-5A80-19). HAAGSMA TA SEYMOUR KG HIGHHILL CA TORDON 101 MIXTURE HEED AND BRUSH KILLER# MATERIAL SAFETY DATA S H E E T ( F O R M NO. 3 3 6 - 1 5 8 - 7 A >. EVALUATION OF NALCOTROL THICKENING AGENT TO CONTROL DRIFT FROM AERIAL APPLICATION OF TORDON 101 MIXTURE AND GARLON 3A HERBICIDE R8D REPORT (GH-P-103). HARREN LE HARREN LE C O U L T E R LL FLYNN JM GRUMBLES JB HUNTER RC LUDWIG PD OSBORNE DW RYDER JC SMITH ML WRIGHT WG BAURIEDEL HR DISHBURGER HJ GERONIMO J HANSON RG HYMAS TA MCCOLLISTER DD PRUITT ME SAUNDERS ES TURNER GO NUMBER DOCUMENT 953 AUTHOR DOM ADDRESSEE COPYEE DOCUMENT 95A DATE 02/17/77 TYPE AUTH PAGES 1 RITTY PM 02/29/72 LEGAL 29 ^ AUTHOR ADDRESSEE: COPYEE: DOCUMENT DOM / y 955 03/05/80 LETTER AUTHOR ADDRESSEE COPYEE: DOM LOTTRITZ G ALLISON ME FEARS RD MATSON AJ s MARREN LE USDA FS BEACHELL GR KARWAHL JH DOCUMENT AUTHOR: ADDRESSEE* COPYEE: 956 * 12/13/7A LETTER NORRIS LA OR ST UNIV BONNEVILLE POMER ADMIN GROSS F BERGMAN E MONTGOMERY M DOCUMENT S' 957 S 09/24/79 TECH AUTHOR: DOM ADDRESSEE: COPYEE: 2 k' AS ' DOCUMENT AUTHOR: ADDRESSEE: COPYEE 958 DOM DOM DOM KARMAL 03/19/79 JH b -c. LETTER MARREN LE COLBY RM ALLISON HE REIMER CA 2- O h-4 CO TITLE PAGE 138 TRI C L OPYR, M-4021, M-3724, T O R D O N 101 R, T O R D O N 10 P E R C E N T PELLETS, TORDON 5 PERCENT PELLETS. REQUEST FOR GRANT (KANSAS STATE UNIVERSITY). TECHNICAL INFORMATION IN SUPPORT OF APPLICATION FOR AMENDED R E G I S T R A T I O N OF ESTERON 2 H E R B I C I D E (EPA R E G I S T R A T I O N NO. 464-205) FOR USE AS A TANK MIXTURE WITH TORDON 101 MIXTURE HERBICIDE (EPA REGISTRATION NO. 464-306) TO OBTAIN IMPROVED CONTROL OF CERTAIN 245T RESISTANT WOODY PLANT SPECIES ON FOREST PLANTING SITES. RESPONSE TO QUESTIONS REGARDING NITROSAMINE CONTENT IN TORDON 101 MIXTURE CTTL. CRUMMETT W KARWAL JH DAVIDSON JH NORRIS MG CONTAMINATION SURVEY AT TORDON 101 SPILL SITE. TORDON 101 MIXTURE WEED AND BRUSH KILLER (MATERIAL SAFETY DATA SHEETH87120). DRIFT CONTROL SPECIFICATIONS FOR TORDON 101 IN FORESTRY. BEACHELL GR FREDERICK DM NUMBER lATE DOCUMENT 959 02/05/70 AUTHOR: ADDRESSEE* COPYEE* DOM DOM I CAH I JFP I PDL / DOCUMENT 960* 02/05/70 AUTHOR: ADDRESSEE* COPYEE: DOM DOM I CAH I HF I JMR I PDL I RMM SCHOCH H DOCUMENT AUTHOR* ADDRESSEE* COPYEE: 961 ^ 01/23/68 KLIGMAN AM ROME VK DOCUMENT 962 00/00/00 AUTHOR: LAMB JC ADDRESSEE* COPYEE: DOCUMENT 963 12/15/A9 AUTHOR: DOM ADDRESSEE* DRILL VA COPYEE: DOCUMENT 9 6 A V / AUTHOR: NACA ADDRESSEE: COPYEE: 09/12/66 TYPE PAGES REPORT 7 GETZENDANER ME HAMAKER JM I CSM I JMR MOSS RD ABSTRACT GETZENDANER ME HAMAKER I CSM I JFK I KGS I PMR I TAH JH LETTER UNIV OF PA DOM 2^ CHART REPORT MOORE JA 63 1 LETTER 5 RONE VK MAYNE UNIV COL REPORT X. V V CO or TITLE PAGE 139 TORDON COMPOSITION FOR PRODUCING TORDON 101 MIXTURE IN CANADA (CRI 70 702). PARSEY ES VANHORN RL HANDLEY HF I EEW I KGS SCHOCH H HEBBOURN RO I JFK I NHB TORDON COMPOSITION FOR PRODUCING TORDON 101 MIXTURE IN CAN (CRI 70 702) . PARSEY ES VA N H O R N RL HANDLEY I EES I JFP I MGW I REM MATHEWS HF B HEBBOURN I EEW I JHG I NWB I RJS MOSS RD RG PROGRESS OF TCDD STUDY CTTL. EVALUATION OF 24D, 245T 8 TCDD TOXICITY IN C57BL/6 MICE REPRODUCTION 8 FERTILITY IN TREATED MALE MICE 8 EVALUATION OF CONGENITAL MALFORMATIONS IN THEIR OFFSPRING. MARKS TA UPJOHN 24D AND 245T SAMPLES SENT FOR TOX TESTS IN DOGS, TEST RESULTS ON OTHER ANIMALS GIVEN CTTL. QUESTIONS THE VALIDITY OF THE REQUIREMENT FOR RESTRICTING LIVESTOCK FROM SPRAYED AREAS FOR SEVEN DAYS AFTER APPLICATION CTTL. NUMBER DATE TYPE PAGES DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 965 07/09/65 LETTER DOM ROME VK HOSPITAL OF THE UNIV OF KLIGMAN DOM ROHE VK HOYL^K KRAMER AM TITLE SUGGESTIONS FOR TOXICOLOGY TESTS USING TCDD CTTL. GORDON HL PETERSON JE HOLDER BB SILVERSTEIN L PAGE IAO DOCUMENT 966 07/01/70 AUTHOR: ADDRESSEE COPYEE: BAYLEY ND BICKHIT HART P LEGIS LETTER USDA HART PA US SENATE 9 ^ (EFFECTS OF 245T AND RELATED HERBICIDES ON MAN AND THE ENVIRONMENT). BYERLY TC BAYLEY ND DOCUMENT AUTHOR: ADDRESSEE: COPYEE: DOCUMENT 967 ' S 09/00/71 COURTNEY KD y 96B 00/ 00/00 AUTHOR: DOM ADDRESSEE: COPYEE: REPORT EPA REPORT 17 T E R A T O L O G Y ST UD I ES M I T H C H L O R O D I B E N Z O - P - D I O X I N S . v/ 1 U.S. EPA SUSPENSION OF 245T SILVEX FOR USES ON RIGHTSOFHAY FORESTRY PASTURES. DOCUMENT 969\ f 01/00/80 AUTHOR: MONSANTO ADDRESSEE: COPYEE: SUSSKIND RR NEHS ZACK JA A THE MORTALITY EXPERIENCE OF WORKERS EXPOSED TO TCDD IN A TRICHLOROPHENOL PROCESS ACCIDENT (JOURNAL OF OCCUPATIONAL MEDICINE 22(1) 11-14, 1980). DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 970 CROSBY 03/25/77 DG REPORT UC DAVIS 2^ ENVIRONMENTAL DEGRADATION OF TCDD(TCDD)(SCIENCE 195, 1337-1338). MONG AS DOCUMENT 971 ^ 08/00/80 AUTHOR: ADDRESSEE: COPYEE: COOK RC TOWNSEND JC NEMS REPORT DOM UNIV OF MI 3 MORTALITY EXPERIENCE OF EMPLOYEES EXPOSED TO TCDD (JOUR OF OCCUPATIONAL MEDICINE 22(8) 530-532). OTT MO SILVERSTEIN LG -c SL) H "4 V CO CD NUMBER / D A T E DOCUMENT 972 V 00/00/78 AUTHOR? ADDRESSEE! COPYEEi BARNARD DOW KALNINS WADE CE SD RP TYPE PAGES REPORT 24 BEYER JE FRAUSON LE KEYES DG DOCUMENT AUTHOR: ADDRESSEE COPYEE 973 08/28/78 MCHUGH MF ASPLUNDH LETTER US HSE REPS MEHRE FW 1 DOCUMENT 974 08/21/78 AUTHOR ASPLUNDH ADDRESSEE EPA COPYEE LETTER MEHRE FW 1 DOCUMENT 975 ^ 08/30/78 AUTHOR ADDRESSEE COPYEE ASPLUNDH EPA FINCHER MH SENATE GA LETTER HICKS JH FOSTER RL WILLIAMS R 1 DOCUMENT 976 ^ 07/18/78 AUTHOR DAVEY TREE EXPERT ADDRESSEE EPA COPYEE LETTER JEFFERS WA 2 DOCUMENT AUTHOR: ADDRESSEE COPYEE 977 ^ 09/05/78 ABBOTT RE ASPLUNDH LETTER 1 DAVEY TREE EXPERT SKELTON J DOCUMENT 978 ' 09/14/78 AUTHOR: ASPLUNDH ADDRESSEE EPA COPYEE: CHILES LM LETTER SHIVER D STONE R 2 TITLE PAGE 141 RESULTS OF A TWO YEAR TCDD IN RATS CTOX AND CARREON RM HUMISTON CG KOCIBA RJ CHRONIC TOXICITY AND APPLIED PHARMACOLOGY DITTENBER DA HUMMEL RA PARK CN ONCOGENICITY STUDY 46, 279-303). OF T ELEPHONE CONTACTS TO SOLICIT 245T BENEFIT L ETTERS TO THE EPA. OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. HSE REPS GA RAMSEY T OPP 30000 26. T E L EPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. 245T RPAR. OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. NUMBER / DATE DOCUMENT 979 ' 09/25/78 AUTHOR: ADDRESSEE! COPYEEi ASPLUNDH EPA BRECKINRIDGE HUDDLESTON H SNYDER G / J DOCUMENT 980 / 10/1 3 / 7 8 AUTHOR: ADDRESSEE COPYEEi ASPLUNDH EPA BOLAND E EARLY J STUDDS G / D O C UMENT 981 'z 0 0 / 0 0 / 0 0 AUTHOR: ADDRESSEE: COPYEE: TYPE PAGES LETTER 1 ROSE G CARTER TL MAZZOLI R LETTER SCHNARR JG BROOKE E MARKEY E TSONGAS P REPORT 3 7 DOCUMENT 982 V^ 0 3 / 1 3 / 7 8 LEGIS 2 AUTHOR EVANS ADDRESSEE: COPYEE: US HSE REPS DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 983 ^ 06/28/78 LETTER CAMPBELL AIR SERVICE ROHE HB SR KIRBY FOREST INDUS PRICE T / DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 98A \ / 08/02/78 MEMO CAMPBELL AIR SERVICE ASPLUNDH EAKIN JG SKELTON J 2 1 DOCUMENT AUTHOR: ADDRESSEE COPYEE: 985 v / / 08/23/78 LETTER EASTERN SHORE NATURAL GA MORRIS H ASPLUNDH SKELTON J 1 _c W CO UJ G O 4L TITLE OPP 30000 26. TO THE EPA. PAGE 142 TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS FORD N NATCHER H HUBBARD C PERKINS C OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. CONTE S MOAKLEY J US HSE REPS DRINAN R ONEILL T CONTRACTORS. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. A BILL TO ABOLISH THE EPA C95TH CONGRESS, 2ND SESSION. IN THE HOUSE OF REPRESENTATIVES). TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA NUMBER DATE DOCUMENT 986 09/15/78 AUTHOR ARCO PIPE LINE ADDRESSEE ASPLUNDH COPYEE D O C U M E N T 9 8 7 1/ AUTHOR ADDRESSEE' COPYEE 00/00/00 DOCUMENT AUTHOR: ADDRESSEE' COPYEE 988 1 06/28/78 DEPT OF TRANS PA EPA DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 989 * 05/25/78 DEPT OF TRANS ME CASTLE D DEPT OF TRANS ME D O CUMENT 990 '/ 08/03/78 AUTHOR: DEPT OF TRANS ME ADDRESSEE ASPLUNDH COPYEE: D O CUMENT 991 V/" 0 8 / 0 3 / 7 8 AUTHOR: DEPT OF TRANS IA ADDRESSEE: EPA COPYEE: DOCUMENT 992 08/07/78 AUTHOR: RINARD JE ADDRESSEE EPA COPYEE: DOCUMENT 993 ^ AUTHOR: ADDRESSEE COPYEE: 00/00/00 H-* -X. CO p 0> C O TYPE LETTER PAGES 2 CLAPP GE HOLEWINSKI DE REPORT 7 LETTER ROSS RS 1 LETTER M ALLAR RL EPA STONE TM LETTER STONE TM SKELTON J 1 1 LETTER GIVEN RH 1 LETTER 1 REPORT 1 TITLE PAGE IAS 2A5T (RPAR). TELEPHONE CONTACTS TO SOLICIT 2 T BENEFIT LETTERS TO THE EPA. PIPELINES. TELEPHONE CONTACTS TO SOLICIT 2A5T BENEFIT LETTERS TO THE EPA. TELEPHONE CONTACTS TO SOLICIT 2A5T BENEFIT LETTERS TO THE EPA. TELEPHONE CONTACTS TO SOLICIT 2A5T BENEFIT LETTERS TO THE EPA. RISSEL MC TELEPHONE CONTACTS TO SOLICIT 2A5T BENEFIT LETTERS TO THE EPA. OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 2A5T BENEFIT LETTERS TO THE EPA. CODE NO. 30000 76. TELEPHONE CONTACTS TO SOLICIT 2A5T BENEFIT LETTERS TO THE EPA. TELEPHONE CONTACTS TO SOLICIT 2A5T BENEFIT LETTERS TO THE EPA. N U M B E R ^ / DATE DOCUMENT AUTHOR: ADDRESSEE: COPYEE: 994 06/29/78 HENDRICKSON CH DOCUMENT AUTHOR: ADDRESSEE-* COPYEE: / 995 07/13/78 BRIGGS GM HENDRICKSON CM DOCUMENT AUTHOR: ADDRESSEE COPYEE: 996 Vr/ C0.8/09 / 7 8 BRIGGS GM ASPLUNDH TYPE PAGES LETTER 1 MARKET OPINION RES LETTER 1 NY DEPT OF TRANS MARKET OPINION RES LETTER 1 NY DEPT OF TRANS HOLEMINSKI DE DOCUMENT 997 0S/1A/78 LETTER AUTHOR: ADDRESSEE COPYEE: DEPT OF HIGHWAYS EPA ASPLUNDH ROBB ET 8 TRANS HUNDLEY CASSELL RL BB DOCUMENT AUTHOR: ADDRESSEE COPYEE 998 ^ 08/16/78 CHILDERS FA ASPLUNDH LETTER 1 GA DEPT OF TRANS HOLEWINSKI DE DOCUMENT 999 09/11/78 AUTHOR MD DEPT OF TRANS ADDRESSEE: EPA COPYEE: LONG C US SENATE DOCUMENT 1000 AUTHOR: ADDRESSEE: COPYEE: 00/ 0 0 / 0 0 LETTER ! MOFFETT RC MCMATHIAS C JR REPORT < DOCUMENT 1001 ^ OA/13/78 AUTHOR: ADDRESSEE COPYEE: BOGLE GH JR d -c h~* (T O REPORT RH BOGLE CO TITLE PAGE 144 TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. RPAR OF PRODUCTS CONTAINING 245T. OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. CLEMENTS HR HOLEHINSKI TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. 245T RPAR. OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. SARBANES PS US HSE REPS HIGHWAYS. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. RR BRUSH CONTROL. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. NUMBER / DATE DOCUMENT 1002 V 08/17/78 AUTHOR: BOGLE JB ADDRESSEE ASPLUNDH COPYEE: TYPE PAGES LETTER RH BOGLE CO SKELTON J 1 TITLE PAGE 145 TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA DOCUMENT 1003 / 08/29/78 LETTER 2 AUTHOR: LOUISVILLE 8 NASHVILLE R ROSAMOND TR ADDRESSEE* EPA COPYEE* ASPLUNDH CARTER TL MAZZOLI RL SKELTON J US SENATE S DOCUMENT 1004 08/31/78 LETTER 2 AUTHOR: ADDRESSEE* COPYEE: BESSEMER & LAKE EPA HEINZ HJ US SENATE ERIE RR WACKENHUT JB MARKS ML OPP 30000 26. T E LEPHONE CO N T A C T S TO SOLICIT 2 45T BENEFIT LETTERS TO THE EPA. FORD WH SNYDER 0 HUDDLESTON HD US HSE REPS OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. SCHWEIKER RS US HSE REPS DOCUMENT 1005 ^ 00/00/00 AUTHOR* ADDRESSEE* COPYEE: /' REPORT 4 RAILROADS. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. DOCUMENT 1006 1 07/21/78 AUTHOR* CENTRAL ELECTRIC ADDRESSEE* EPA COPYEE: DANFORTH J LETTER POWER C HAAKE WJ EACH OF MO 2 OPP 30000 26. TELEPHONE TO THE EPA. REPRESENTATIV EAGLETON TF CONTACTS TO SOLICIT US SENATE 245T BENEFIT LETTERS DOCUMENT 1007 AUTHOR* ADDRESSEE* EPA COPYEE* X * 07/27/78 / V DOCUMENT 1008 08/15/78 AUTHOR: KRAUSE M ADDRESSEE: EPA COPYEE: LETTER LETTER KUTTER JP 1 1 TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. PROHIBITION ON USE OF 245T FOR RIGHTOFWAY CLEARANCE. CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. THUMB ELECTRIC COOPERATI TELEPHONE NUMBER . DATE DOCUMENT 1009 * 08/21/78 AUTHORi JAFFRE LE ADDRESSEE* EPA COPYEE* TYPE LETTER PAGES 1 TITLE PAGE 146 PROHIBITION ON USE OF 245T FOR RIGHTOFHAY CLEARANCE. OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. DOCUMENT 1010 08/31/78 LETTER 3 OPP 30000 26. TO THE EPA. AUTHOR* DELAWARE COUNTY ELECTRIC GIFFORD R ADDRESSEE: EPA COPYEE* ASPLUNDH DELAWARE COUNTY ELECTRIC IVES J NRECA PRESCOTT CP TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS KULP F , /DOCUMENT 101 00/ 00/00 AUTHOR* ADDRESSEE* COPYEE: REPORT 17 RURAL E LE CT R IC COOPS. T E L E P H O N E C O N T A C T S T O S O L I C I T 245T BENEFIT LETTERS TO THE EPA. DOCUMENT 1012 v 08/11/78 AUTHOR* WARREN D ADDRESSEE EPA COPYEE* LETTER 1 OPP 30000 26. TO THE EPA. WAYNEWHITE COUNTIES ELEC TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS / DOCUMENT 1013 l/ 09/07/78 LETTER AUTHOR* BOSSIER RURAL ELECTRIC ADDRESSEE* EPA COPYEE* BURGESS JC 2 245T RPAR. OPP 30000 26. T E L E P H O N E CO N T A C T S TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. DOCUMENT 1014 AUTHOR* ADDRESSEE* COPYEE: oo/oo/oo REPORT 19 M I N O R U T I LITIES. T E L E P H O N E C O N T A C T S T O S O L I C I T 24 5 T BENEFIT LETTERS TO THE EPA. DOCUMENT AUTHOR* ADDRESSEE COPYEE: y 1015 05/16/78 METROPOLITAN EDISON EPA DENNO WH JOHNS HR JR R O B I D O U X HL US SENATE LETTER ULRICH ES DUDDLEY RE LANGLEY F ROSSMAN WR YATRON G 2 TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. HEINZ HJ III MANBECK CF SCHWE1KER RS JARMOSKA DR OPAKE MA US HSE REPS SD LP OQ t o NUMBER y DATE DOCUMENT 1016 V 05/26/78 AUTHOR KENNY PJ ADDRESSEE EPA COPYEE TYPE PAGES TITLE PAGE 147 LETTER 1 REGISTRATION PROCEEDINGS CONCERNING PESTICIDE PRODUCTS CONTAINING 245T (OPP 3000036). TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. NEW ENGLAND POWER SERVIC DOCUMENT 1017 05/31/78 AUTHOR JOHNSTONE RA ADDRESSEE COPYEE / LETTER 2 MONONGAHELA POWER TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. DOCUMENT 1018 06/01/78 AUTHOR DETROIT EDISON ADDRESSEE EPA COPYEE EISELE PJ LETTER LEONARD DA GESS N E R JJ 3 245T - NOTICE OF REBUTTABLE PRESUMTION 43FR17116, ET SEO., 780421. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. HEIDRICH A JR KNIGHT JE DOCUMENT 1019 06/02/78 AUTHOR SPANGLER PE ADDRESSEE EPA COPYEE EPA COULTER R GOODLING WF MOORHEAD WS SCHWE1KER RS WALGREN D LETTER 3 WEST PENN POWER AMMERMAN JS DENT JH HEINZ H J III MURPHY AJ SHUSTER EG 245T HERBICIDE REVIEW. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. BECKWITH C DOW J O H N SO N EL MURTHA JP US HSE REPS COSTLE D GAYDOS JM JOHNSTON PH MYERS GA US SENATE DOCUMENT 1020 07/03/78 AUTHOR: ADDRESSEE' COPYEE: RUDDICK I EPA AMCHEM CANNON F KIDDER H LETTER 1 NONRESTRICTIVE USE OF 245T FOR BRUSH CONTROL. OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. ANTRIM LYNN CAPLINGER B NELSON TREE SERVICE ASPLUNDH DEWILDE RC BLUME TREE SERVICES FRITSCH DW DOCUMENT 1021 07/06/78 AUTHOR: IVES JS ADDRESSEE: ASPLUNDH COPYEE: LETTER 1 TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. NATL RURAL ELECTRIC COOP GALVIN MT DOCUMENT 1022 07/07/78 LETTER AUTHOR: POWER AUTHORITY OF THE S SAROKWASH PJ ADDRESSEE: ASPLUNDH SKELTON J COPYEE: 1 9J (" -* 0) -o CO TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. HUMBER / D A T E ___________________________ v . . __________ DOCUMENT 1023 07/07/78 AUTHOR: KG&E ADDRESSEE: ASPLUNDH COPYEE: TYPE PAGES LETTER PICKARTS LA SKELTON J 1 DOCUMENT 1024 07/14/78 AUTHOR: COLEMAN MC ADDRESSEE: EPA COPYEE: ASPLUNDH HOLLAND KL SPENCE F LETTER 2 SC ELECTRIC 8 GAS DAVIS MJ HOLLINGS EF THURMOND STROM DOCUMENT 1025 07/19/78 AUTHOR: GORDON DA ADDRESSEE: COPYEE: DOCUMENT 1026 / , 07/20/78 AUTHOR: HOLLOWAY JE ADDRESSEE-' EPA COPYEE: PERCY CH US SENATE LETTER 1 LETTER 2 S O U T H E R N IL POWER SIMON P DOCUMENT 1027 ^ AUTHOR: MOSS RH III ADDRESSEE: EPA COPYEE: LETTER VEPCO 2 DOCUMENT 1028 ^ 08/01/78 AUTHOR: SOUTHERN CA EDISON ADDRESSEE: ASPLUNDH COPYEE: ECKMAN JR LETTER STLAURENT D SKELTON J 1 DOCUMENT 1029 v 08/11/78 AUTHOR: NOSSE RA ADDRESSEE EPA COPYEE: ASPLUNDH US HSE REPS e f -XL So 41 0 LETTER 3 HOLEWINSKI DE US SENATE TITLE PAGE 148 TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. DERRICK B JENRETTE JW JR US HSE REPS HOLEHINSKI DE MANN JR US SENATE TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. OPP 30000 26. TO THE EPA. COOP TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS STEVENSON AE US HSE REPS R E B U T T A L R E S U M P T I O N A G A I N S T R E G I S T R A T I O N C R P A R 2<*5T>. OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. TELEPHONE CONTACTS TO SOLICIT 2A5T BENEFIT LETTERS TO THE EPA. OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. METZENBAUM HM REGULA R NUMBER /DOCUMENT 1030 DATE 08/14/78 AUTHOR: ADDRESSEE: COPYEE: DAUBERT RL BARTLETT D DANFORTH J RISENHOOVER US SENATE T TYPE PAGES TITLE LETTER 2 245T CHEMICAL. OPP 30000 26. BENEFIT LETTERS TO THE EPA. KAMO ELECTRIC COOPERATIV PAGE 149 T E L E P H O N E CONTACTS TO SOLICIT 245T BELLMON H EAGLETON T SKELTON I YOUNG G BOLLING R ICHORD R TAYLOR G COLEMAN T JONES JR US HSE REPS DOCUMENT 1031 1 / ^ 0 8 / 1 7 / 7 8 AUTHOR: ATLANTIC ELECTRIC ADDRESSEE: EPA COPYEE: LETTER 2 MORGENWECK FE OPP 30000 26. TO THE EPA. DOCUMENT 1032 08/28/78 AUTHOR: ADDRESSEE: COPYEE: ME PUBLIC SERVICE EPA COHEN W US HSE REPS LETTER 2 NORSWORTHY H EMERY D US SENATE OPP 30000 26. THE EPA. HATHAWAY W MUSKIE E DOCUMENT 1033 09/13/78 AUTHOR: ADDRESSEE: COPYEE: BALDWIN MR EPA ASPLUNDH JACOBS A JR LETTER 2 OPP 30000 26. TO THE EPA. INDIANAPOLIS POWER 8 LIG BAYH B LUGAR RG EVANS DW US HSE REPS HOLEWINSKI DE US SENATE DOCUMENT 1034 ' S 08/31/78 AUTHOR: A L T H E I D E WL ADDRESSEE: EPA COPYEE: COLEMAN ET LETTER 1 OPP 30000 26. TO THE EPA. FARMERS ELECTRIC COOPERA TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS EAGLETON TF US HSE REPS US SENATE DOCUMENT 1035 09/18/78 LETTER 2 AUTHOR' EASTERN IA LIGHT 8 POWER SCHWABENLANDER A ADDRESSEE: EPA COPYEE: / OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. DOCUMENT 1036 09/21/78 AUTHOR: POTOMAC EDISON ADDRESSEE: EPA COPYEE: ASPLUNDH LETTER WATSON MR HOLEWINSKI DE OPP 30000 26 - USAGE, ALTERNATIVE AND BENEFITS OF THE HERBICIDE 245T. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. V -C or NUMBER DATE DOCUMENT 1037 10/02/78 AUTHOR BRENNEMAN HS ADDRESSEE EPA COPYEE ADAMS GL MADIGAN ER US SENATE D O C U M E N T 1038 v/ 1 0 / 0 4 / 7 8 AUTHOR MO POWER 8 LIGHT ADDRESSEE EPA COPYEE ASPLUNDH ICHORD R . DOCUMENT 1039 ^ 10/11/78 AUTHOR GILLESPIE JL ADDRESSEE EPA COPYEE DENT JH US SENATE /D O C U M E N T 1040 10/11/78 AUTHOR DELMARVA POWER ADDRESSEE COPYEE / DOCUMENT 1041 10/12/78 AUTHOR MORROW PA ADDRESSEE EPA COPYEE CASH HD VARNUM DF DOCUMENT 1042 * 10/18/78 AUTHOR MI POWER ADDRESSEE EPA COPYEE yD O CUMENT 1043 10/18/78 AUTHOR BROOKS HE ADDRESSEE EPA COPYEE ASPLUNDH WILSON AC TYPE LETTER IL P O W E R ASPLUNDH PERCY C PAGES 2 LETTER QUICK GL DANFORTH J US HSE REPS 2 LETTER 2 PENN LINE SERVICE HEINZ J III LETTER HAMILTON W 1 LETTER 2 NEW BEDFORD GAS 8 DEMATOS AB LETTER SMITH L 1 LETTER 2 IN 8 MI ELECTRIC RUFF DE TITLE PAGE 150 OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. HOLEWINSKI DE STEVENSON A I D L E M A N LL US HSE REPS REREGISTRATION OF THE HERBICIDE 245T. OPP30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. EAGLETON T US SENATE HOLEWINSKI DE OPP 30000 26. T E LEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. SCHWEIKER RS US HSE REPS OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. OPP 30000 26. REGISTRATION PROCEEDINGS CONCERNING 245T. EDISON HARTSHORN JA ROUSSEAU RA OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. SKELTON J WARTZOK DF NMBER DOCUMENT 1044 V DATE 00/00/00 AUTHOR: ADDRESSEE: COPYEE: BOSTON EDISON / DOCUMENT 1045 00/00/00 AUTHOR: ADDRESSEE COPYEE: DOCUMENT 1046 AUTHOR ADDRESSEE COPYEE: 00/00/00 D O C U M E N T 1047 v/ ^ i i / 0 2 / 7 8 AUTHOR: ASPLUNDH ADDRESSEE DON COPYEE: DOCUMENT 1048 02/01/79 AUTHOR ADDRESSEE COPYEE: DOM DOM NORRIS MG s DOCUMENT 1049 v 04/21/78 AUTHOR: BARRONS K ADDRESSEE COPYEE: HESS GE DOCUMENT 1050 y/ 08/02/78 TYPE MEMO PAGES 3 REPORT LITTLE RH REPORT 15 CHART 1 LETTER 1 HOLEMINSKI DE S M ITH LL DISTRB LETTER SMITH LL DAVIDSON JH TRAYNOR MJ 2 NEMS DOM 1 LEGIS 4 AUTHOR: EPA ADDRESSEE COPYEE: J O H N S O N EL TITLE PAGE 151 REBUTTABLE PRESUMTION AGAINST REGISTRATION AND CONTINUED R E G I S T R A T I O N OF PEST I C I D E PROD U C T S C O N T A I N I N G 245T. OPP 30000 26. TELEPHONE CONTRACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. MAJOR UTILITIES. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. SUMMARY OF TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO EPA. ASPLUNDH TELEPHONE SOLICITATION. TELEPHONE CONTACTS TO SOLICIT 245T BENEFIT LETTERS TO THE EPA. FREDERICK DM HILLIAMS CS LENG ML 245T RPAR REVIEW IS NOT A SUSPENSION OF USE. EPA PESTICIDE PROGRAMS REBUTTABLE PRESUMPTION AGAINST REGISTRATION AND CONTINUED REGISTRATION OF PESTICIDE PRODUCTS CONTAINING 245 TRICHLOROPHENOL AND ITS SALTS (FED REGISTER 43(149), 34026-34028, 780802). NUMBER DOCUMENT 1051 DATE 00/00/00 TYPE CHART PAGES 1 AUTHOR: JENSEN DJ ADDRESSEE: COPYEE: / ,D O C UMENT 1052 07/17/78 AUTHOR: DOW ADDRESSEE: DOW GLEESON JG MCCOLLISTER DD COPYEE: MEMO ' LENG ML CRUMMETT WB GRAY JA SCHROETER RH 1 DOCUMENT 1053 AUTHOR: DOW ADDRESSEE: DOW COPYEE: 05/09/78 REPORT KOCIBA RJ DAVIDSON JH 4 D OC U M E N T 1054 L / 01!5 / 3 1 / 7 8 LETTER AUTHOR: DAVI DSON JJH DOW ADDRESSEE: PROPONENTS OF PHENOXY HE COPYEE: 1 DOCUMENT 1055 ^ 08/16/78 AUTHOR: CROSBY DG ADDRESSEE: BLAIR EH COPYEE: LETTER UC DAVIS DOW 2 DOCUMENT 1056 08/16/78 AUTHOR: ASPLUNDH ADDRESSEE EPA COPYEE: DOCUMENT 1057 05/09/78 AUTHOR: DEPT OF TRANS ME ADDRESSEE: EPA COPYEE: DEPT OF/TRANS ME LETTER DALTON CB LETTER M A L L A R RL MAIRS D 1 2 DOCUMENT 1058 AUTHOR: DOW ADDRESSEE COPYEE: 07/05/78 REPORT MORGAN AH 1 CO TITLE PAGE 152 SUMMARY OF RESIDUES OF SILVEX AND 2A5-TRICHL0R0PHEN0L IN TISSUES OF CATTLE FED 300 PPM OF SILVEX IN THEIR DIET FOR 28 DAYS AND THE DISSIPATION OF THOSE RESIDUES. CHARLOTTE TAYLOR RESPONSE TO 2A5T RPAR NO 310 30000/26. DAVIDSON JH J E N S E N DJ S M I T H LL GETZENDANER ME LAFOLLETTE TRAYNOR MJ SUGGESTED STATEMENT TO BE USED FOR RPAR. SMITH LL GROUP MEETING TO COORDINATE EFFORTS ON RPAR FOR 245T. COVER LETTER FOR CA REBUTTAL TO EPA 245T RPAR CTTL. 2A5T RPAR. OPP 30000 26. TELEPHONE CONTACTS TO SOLICIT 2A5T BENEFIT LETTERS TO THE EPA. 2A5T RPAR. TELEPHONE CONTACTS TO SOLICIT 2A5T BENEFIT LETTERS TO THE EPA. RISSEL MC STONE TM PROPOSED COMPILATION SCHEDULE OF 245T RPAR REBUTTAL SUBMISSION NUMBER DATE DOCUMENT 1059 07/05/78 AUTHOR*ADDRESSEE COPYEE DOW DOW MCCOLLISTER DD DOCUMENT 1060 / ; 00/00/78 AUTHOR: DOW ADDRESSEE: COPYEE: DOCUMENT 1061 ^ AUTHOR! DOW ADDRESSEE: COPYEE: 07/1A/78 DOCUMENT 1062 02/28/79 TYPE PAGES LETTER REPORT MORGAN AH DAVIDSON JH TRAYNOR MJ 1 REPORT RAO KS 29 REPORT RAO KS 25 REPORT A AUTHOR: DOW ADDRESSEE: EPA COPYEE: DOCUMENT 1063 AUTHOR: DOW ADDRESSEE! COPYEE: 00/00/00 DOCUMENT 106A AUTHOR: DOW ADDRESSEE: COPYEE: 06/19/78 DOCUMENT 1065 06/19/78 AUTHOR: DOW ADDRESSEE: DOW MCCOLLISTER DD COPYEE: REPORT 8 REPORT 39 MEMO SCHWETZ BA G E H R I N G PJ RAO KS 1 -X. -t CD TITLE PAGE 153 POLICT QUESTIONS ON THE ORGANIZATION OF THE 2431 RPAR REBUTTAL. GRAY JA LENG ML EVALUATION OF THE MUTAGENIC POTENTIAL OF 245T AND TCDD IN RESPONSE TO A RPAR ON 245T. SCHNETZ BA EVALUATION OF THE MUTAGENIC POTENTIAL OF 245T AND TCDD IN RESPONSE TO A RPAR ON 245T. SCHWETZ BA RESPONSE BY DON TO THE EPA'S DECISION AND EMERGENCY ORDER SUSPENDING REGISTRATIONS FOR CERTAIN USES OF 245T AND 2-(245-TRICHL0R0PHEN0XY) PROPIONIC ACID (SILVEX) IN A NOTICE TO REGISTRANTS DATED 790228. RPAR OF 245T; MUTAGENICITY. RPAR OF 245Ti TERATOGENICITY/FETOTOXICITY AS A TRIGGER. RPAR ON 245T. KOCIBA RJ S M I T H LL LENG ML NUMBER JfT E D O C U M E N T 1066 ^' S 0n 5c //1111 / 7 8 AUTHOR: DAY BE OR ST UNIV HITT JM ADDRESSEE AG EXP STATION COPYEE: TYPE PAGES LETTER HOFFMAN GO PURDUE UNIV 2 DOCUMENT 1067 v AUTHOR: DOW ADDRESSEE DOH COPYEE: DOH SMITH 06/13/78 LL, MEMO LENG ML DAVIDSON JH DONALDS JE TRAYNOR MJ 1 DOCUMENT 1068 v 08/02/78 AUTHOR: FED REGISTER ADDRESSEE: COPYEE: LEGIS 26 DOCUMENT 1069 v 05/03/78 NEMS AUTHOR: PEST 8 TOX CHEM NEHS ADDRESSEE COPYEE 1 DOCUMENT 1070 ^ 05/03/78 NEWS AUTHOR PEST 8 TOX CHEM NEHS ADDRESSEE COPYEE: 3 DOCUMENT 1071 V 06/09/78 LEGIS 1A AUTHOR: CITIZENS FOR ENVIRON ADDRESSEE: COPYEE: HOOLEY DR DOCUMENT 1072 AUTHOR: DOH ADDRESSEE: DOH COPYEE: DOH 05/16/78 S DOCUMENT 107 3 S AUTHOR: DOH ADDRESSEE: DOH COPYEE: DOH 07/06/78 LETTER LENG ML HOLDER BB DAVIDSON MEMO LENG ML K I L IA N DJ DN N FL h 'C h 'C T TITLE BACKGROUND INFORMATION ON RPAR PROCESS C T T L . HOLT HA NEWTON M TX ASM UC BERKELEY PAOE 154 USDA STATE UNIVERSITY ROLE IN 245T RPAR. KAYE SCHOLER WESSEL MR MCCOLLISTER DD (FED REGISTER 43(149), 34029-34054). DOW REGISTERS IMMEDIATE WELCOME TO RPAR NOTICE ON 245T (PEST & TOX C H E M NEWS, 4). EACH FOREST SERVICE USE OF TCDD CONTAINING HERBICIDES TO BE PASSED BY CUTLER (PEST & TOX CHEM NEWS, 9-11). CITIZEN COMMENTS REGARDING 245T USE ON TRANSMISSION LINES BEFORE THE EPA OFFICE OF PESTICIDE PROGRAMS REBUTTABLE PRESUMPTION AGAINST REGISTRATION AND CONTINUED REGISTRATION OF PESTICIDE PRODUCTS CONTAINING 245T. SEVESCO AND 245T RPAR. TRAYNOR MJ 245T RPAR CTTL. HOLDER BB MCCOLLISTER DD NUMBER -A- DOCUMENT 1074V AUTHOR: DOM ADDRESSEE* DOM COPYEE: DOM / DATE 08/16/78 DOCUMENT 1075 V AUTHOR: EPA ADDRESSEE: EPA COPYEE: 00/00/00 DOCUMENT 1076 v AUTHOR: DOM ADDRESSEE: DOM COPYEE: DOM SMITH 04/28/78 LL' y DOCUMENT 1077 07/28/78 AUTHOR: DOM ADDRESSEE: DOM COOPER RD EADIE JD GLOMSKI RL HOLDER BB LEHMAN FR MORGAN AH VATNE RD MOODS CD COPYEE: DOCUMENT 1078 v 05/25/78 AUTHOR: SMITH CL ADDRESSEE: DOM COPYEE: / DOCUMENT 1079 ^ 05/31/78 AUTHOR: DOM ADDRESSEE: DOM COPYEE: DOM KAYE SCHOLER MESSEL MR DOCUMENT 1080 J AUTHOR: ADDRESSEE: I^COPYEE: 00/00/76 TYPE PAGES LETTER 1 MCCOLLISTER DD GEHRING PJ DAVIDSON JH MEMO PERTEL R REECE M 2 MEMO LENG ML HOLDER BB DAVIDSON JH TRAYNOR MJ 1 LETTER M U L F ML BLAIR EH DAVIDSON JH FIERO TH GRAY JA JANTZ OK MANSTON JM RO BE R TS DJ HEAVER MA 3 LETTER USDA LENG ML 1 LETTER LENG ML S MIT H LL DAVIDSON JH MCCOLLISTER 1 DD REPORT 2 PbZ b- h or TITLE 2A5T RPAR. KOCIBA RJ LENG ML SCHHETZ BA S M I T H LL 245T STUDIES FURTHER R E V I EH. HARNICK H 2A5T RPAR MUTAGENICITY STUDIES. SCHHETZ BA GEHRING PJ HULF ML GRAY JA 245-TRICHL0R0PHEN0L RPAR POSITION DOCUMENTS. BOEKER RH DAVIS DH GEHRING PJ HAGERMAN RL KENAGA EE MARTIN PS SCHHETZ BA HILLIAMS CS CAPRICCIOSO JM DEVRIEZE JD GETZENDANER ME HEMBREE JD KOCIBA RJ MCCOLLISTER DD TRAYNOR MJ HINQUIST ME PAGE 155 USDA ROLE IN 2A5T RPAR. HEFNER RE MULLISON HR TCDD MUTAGENICITY JONES GG TRAYNOR MJ NUMBER DATE TYPE PAGES DOCUMENT 1081 AUTHOR: EPA ADDRESSEE EPA COPYEE: 03/00/78 / LETTER REPORT PERTEL R REECE M 2 DOCUMENT 1082 V 04/28/78 AUTHOR: DOM ADDRESSEE: DOM COPYEE: DOM S M I T H LL y DOCUMENT 1083 ^ 06/21/78 AUTHOR: DOM ADDRESSEE: TO ALL MHO MANT TO COPYEE: LETTER LENG ML HOLDER BB DAVIDSON JH TRAYNOR MJ LETTER MARREN LE PREVE 1 2 DOCUMENT 1084 ^ 05/31/78 LETTER AUTHOR: DAVIDSON JH DOM ADDRESSEE: PROPONENTS OF PHENOXY HE COPYEE: DOCUMENT 1085 AUTHOR: DOM ADDRESSEE: COPYEE: t / 00/00/74 TELEX DOCUMENT 1086 * 05/08/78 AUTHOR BECKWITH CL ADDRESSEE: COPYEE: / / DOCUMENT 1087* AUTHOR: ADDRESSEE: COPYEE: 00/00/00 LETTER DOM LETTER 1 hCb-cp D O C U M E N T 1 0 8 8 '' 0 5 / 1 5 / 7 8 AUTHOR: DOM ADDRESSEE: DOM CUMMINS DW HAMMOND LE HUNTER SM REGAN JB STEELE RM COPYEE: t ^ D O M H-*- G R A Y JA r n JANTZ OK ^ MULLISON MR LETTER SMITH LL JR BALDWIN DM FEARS RD HARRISON RP JENTES CE RITTY PM UlLOM RE COLBY RM HAMAGUCHI H JONES GG S M I T H LL TITLE 245T STUDIES, FURTHER REVIEW WARNICK H 245T RPAR, MUTAGENICITY STUDIES SCHWETZ BA GEHRING PJ WULF ML GRAY JA BENEFITS FOR 245T RPAR. PAGE 156 GROUP MEETING TO COORDINATE EFFORTS ON RPAR FOR 2A5T. DOW COMMENTS ON EPA ANNOUNCEMENT OF REVIEW OF 2A5T HERBICIDE. 2A5T RPAR. 2A5T RPAR 2A5T RPAR FIELD PLANS. BEAN JN GRUMBLES JB HUFFMAN JR LICHT CT RYDER JC VANDERSCHAAF DAVIDSON JH HEFNER RE LENG ML STEARNS JH P BYRD BC HALE DB HUNTER JH LUDWIG PD SMITH ML HARREN LE GANTZ RL HUNTER RC MCCOLLISTER TRAYNOR MJ DD NUMBER DATE NILLIAMS CS S' DOCUMENT 1089 x / 1 05/22/78 AUTHOR: DON ADDRESSEE: DON COPYEE: DON / TYPE PAGES NRIGHT NG LETTER 1 STEARNS NJ AG DIST SALES MGR DAVIDSON JH DOCUMENT 1090 ^ 06/19/78 AUTHOR DON ADDRESSEE: ALL DIST SALES COPYEE: DON DOYLE JP JANTZ OK MULLISON HR STAMISON PG VRANISH SR / MGR DOCUMENT 1091'' 04/21/78 LETTER 2 REPORT JONES GG ALL FIELD R8D TS8D BOYLE CM DREYER NA LENG ML NILSON A STEARNS HJ HARD HH REPORT 43 \ AUTHOR: EPA ADDRESSEE: COPYEE: DOCUMENT 1092 ^ 07/31/78 PRESENT 25 AUTHOR: DON ADDRESSEE: DON COPYEE: LENG ML s S M ITH LL DOCUMENT 1093 V 04/21/78 AUTHOR: DON ADDRESSEE: COPYEE: BALDNIN DM CUMMINS DN GRUMBLES JB HEFNER RE JANTZ OK LUDNIG PD RITTY PM STEELE RH NARREN LE PROMO 5 BEAN JN DAVIDSON JH HALE DB HUFFMAN JR JENTES CE MCCOLLISTER RYDER JC TRAYNOR MJ NILLIAMS CS DD H-* sj o r -C C O -a TITLE PAGE 157 245T RPAR STATUS. AG SALESPERSONS SMITH LL STAMISON PG INFORMATIONAL MATERIAL 245T RPAR. PERSO DAVIDSON JH GORING CA MACDONALD LA PRIDDY JK TOWNSEND RM WILLIAMS CS DONALDS JE HUNTER RC MOSS RD S M I T H LL TRAYNOR MJ REBUTTABLE PRESUMPTION AGAINST REGISTRATION AND CONTINUED REGISTRATION OF PESTICIDE PRODUCTS CONTAINING 245T(FEDERAL REGISTER 43(78), 17116-17157). RESPONSE OF DOW CHEMICAL U.S.A. TO NOTICE OF REBUTTABLE PRESUMPTION AGAINST REGISTRATION AND CONTINUED REGISTRATION OF PESTICIDE PRODUCTS CONTAINING 245T. WHAT THE 245T RPAR MEANS TO YOU. . BYRD BC FEARS RD HAMMONDLE HUNTER RC LENG ML MOSS RD SMITH ML ULLOM RE WRIGHT WG COLBY RW GRAY JA HARRISON RP HUNTER SM LICHY CT MULLISON WH STEARNS WJ VANDERSCHAAF P NUMBER / DATE DOCUMENT 109A `y 0 5 / 3 0 / 7 8 AUTHOR: DON ADDRESSEE DON COLBY RH GRAY JA HARRISON RP HUNTER SM LICHY CT MULL ISON NH STEARNS NJ VANDERSCHAAF P COPYEE / DOCUMENT 1095 ^ 08/17/78 AUTHOR: DON ADDRESSEE COPYEE: TYPE PAGES LETTER S MIT H LL BALDNIN DM CUMMINS DN GRUMBLES JB HEFNER RE JANTZ OH LUDNIG PD RITTY PM STEELE RN NARREN LE 2 NEHS EADIE JD DOCUMENT 1096 AUTHOR DON ADDRESSEE* COPYEE* 05/01/78 REPORT LENG ML 7 D O C U M E N T 1097 %. 0 5 / 0 1 / 7 8 AUTHOR: DON ADDRESSEE* DON CRUMMETT HB GORING CA HOERGER FD JONES GG MCCOLLISTER DD NORRIS JM PRUITT ME SHADOFF LA STEARNS NJ NILLIAMS CS COPYEE* DON LETTER LENG ML BLAIR EH DAVIDSON JH GRAY JA HOLDER BB KOCIBA RJ MOOLENAAR RJ OCONNOR JN RONE VK SHEETS DP TRAYNOR MJ DON 2 DOCUMENT 1098 07/00/78 REPORT AUTHOR* CA DEPT FOOD AND AG ADDRESSEE* COPYEE: CROSBY DO 13 TITLE \ 245T RPAR-BACK-UP-LITERATURE BEAN JN DAVIDSON JH HALE DB HUFFMAN JR JENTES CE MCCOLLISTER RYDER JC TRAYNOR MJ WILLIAMS CS DD BYRD BC FEARS RD HAMMOND LE HUNTER RC LENG ML MOSS RD SMITH ML ULLOM RE WRIGHT WG PAOE 15 DOW CHEM USA STATEMENT RELATIVE TO EPA RPAR CONCERNING 245T (DOWICIDE 2). DOW 2A5T RPAR-REVIEW OF EPA'S RATIONALE AND THEIR CALCULATIONS FOR EXPOSURE TO 2A5T AND TCDD. 2A5T RPAR - A GAME BY EPA'S RULES. DOM BLAU GE BUMB RB DONALDS JE GEHRING PJ HART RD HFFNER RE JANTZ OK JOHNSON JE LANGNER RR MACDONALD LA MOSS RD MULL ISON WR OREFFICE PF PARK CN SCHROETER RH SCHNETZ BA S M I T H LL STAMISON PG VACCARO JR WESSEL MR REBUTTAL TO EPA'S INTERPRETATION OF DATA REGARDING THE HEALTH HAZARDS OF 245T. KNAAK JB UC DAVIS NUMBER DOCUMENT 1099 DATE 07/25/78 TYPE LEGIS PAGES 11 AUTHOR EPA ADDRESSEE COPYEE / JOH N S O N EL DOCUMENT 1100 ^ AUTHOR EPA ADDRESSEE DOM COPYEE 09/08/78 LETTER 1 JOH N S O N EL MCCOLLISTER DD DOCUMENT 1101 AUTHOR EPA ADDRESSEE COPYEE 04/12/78 REPORT ONEILL 3 D O C U M E N T 1102 1/ AUTHOR ADDRESSEE COPYEE 05/22/78 LETTER 2 DOCUMENT 1103 { / AUTHOR EPA ADDRESSEE EPA COPYEE 08/26/77 MEMO PERTEL R REESE M 1 DOCUMENT 1104 09/08/78 LEGIS 1 AUTHOR EPA ADDRESSEE COPYEE J O H NSO N EL DOCUMENT 1105 04/12/78 NEHS 1 AUTHOR CITZENS NATL FOREST COAL JANSSON E ADDRESSEE COPYEE S OT CT? TITLE PAGE 159 PESTICIDE PROGRAMS NOTICE OF REBUTTABLE PRESUMPTION AGAINST REGISTRATION AND CONTINUED REGISTRATION OF PESTICIDE PRODUCTS CONTAINING 295-TRICHL0R0PHEN0L AND ITS SALTS. EXTENSION OF THE PERIOD FOR THE THE SUBMISSION OF RISK REBUTTAL EVIDENCE FOR 295-TRICHL0R0PHEN0L WAS GRANTED C TTL. FOR IMMEDIATE RELEASE WEDNESDAY 780912 295T PESTICIDE BEING REVIEWED BY EPA (ENVIRONMENTAL NEWS). EFFECTS FROM 295T SPRAYING IN CA CTTL. TCDD DIOXIN MUTAGENICITY. WARNICK H RPAR AND CONTINUED REGISTRATION OF PESTICIDE PRODUCTS CONTAINING 295 TRICHLOROPHENOL AND ITS SALTS(FED REGISTER 93(180), 91269, 780915). CITIZENS NATL FOREST COALTN CALLS UPON THE EPA TO IMMEDIATELY HALT THE SALES AND PRODUCTION OF ALL PRODUCTS CONTAMINATED WITH TCDD DIOXIN, THE MOST DEADLY CHEMICAL EVER SYNTHESIZED. STUBER J LLEN JR NUMBER DATE DOCUMENT 1106 V 07/10/80 AUTHOR FOE ADDRESSEE COSTLE D COPYEE DOCUMENT 1107 v 10/2A/80 AUTHOR ADDRESSEE COPYEE BUMB RR SHADOFF LA HUMMEL RH HOODS JS DOCUMENT 1108 AUTHOR FOE ADDRESSEE COPYEE: 07/10/80 DOCUMENT 1109 AUTHOR: FOE ADDRESSEE FOE COPYEE 01/16/80 DOCUMENT 1110 v 06/00/79 TYPE PAGES LETTER REPORT JANSSON E EPA 2 NEWS REPORT CRUMMETT MB STEHL RH KAGEL RO 7 REPORT JANSSON E 1 LETTER ZEMANSKY GM JANSSON E 3 REPORT 3 AUTHOR ENVIRON SCIENCE 8 TECH ADDRESSEE COPYEE: I LRE DOCUMENT 1111 05/00/78 LETTER AUTHOR: NEH ENGLAND POHER SERVIC VANBOSSUYT R ADDRESSEE COPYEE: DOCUMENT 1112 v 10/26/80 AUTHOR: HOHARD R ADDRESSEE: COPYEE: NEHS 2 TORONTO STAR TITLE PAGE PETITION 2 PICLORAM AND CANCER SLIDE REVIEW STANDARDIZATION. 160 TRACE CHEMISTRIES OF FIREl A SOURCE OF CHLORINATED DIOXINS (SCIENCE 210, 385-390). LAMPARSKI LL DON M I L L E R DL LUOMA EV CUTIE SS NESTRICK TJ SUPPORTING DOCUMENTS TO PETITIONS. DISCUSSION OF THE INADEQUACY OF THE SAFETY INFORMATION IN THE EPA PESTICIDE REGISTRATION FILES CTTL. EPA SUSPENDS THE MAJOR USES OF THO HERBICIDES, A LINK BETHEEN FORESTRY SPRAYINGS AND MISCAR R I A G E S IN W OMEN LIVING IN ALSEA, OR, PROMPTED THE EMERGENCY SUSPENSION OF 2A5T AND SILVEX (ENVIRON SCIENCE 8 TECH 13(6), 6A0-6A1). RPAR AND CONTINUED REGISTRATION OF PESTICIDE PRODUCTS CONTAINING 2 4 5 T . OPP 30000 36. TELEPHONE CON T A C T S TO SOLICIT 2A5T BENEFIT LETTERS TO THE EPA. DIOXINS FOUND IN 24D ALARM OTTAWA (TORONTO STAR). NUMBER DATE DOCUMENT 1115 \ / 02/03/76 AUTHOR! LYNCH RS ADDRESSEE-- COPYEE! TYPE ABSTRACT OU LT PAGES 1 DOCUMENT AUTHOR: ADDRESSEE? COPYEE! 04/22/80 NEWS 8 DOCUMENT 1115 00/00/72 AUTHOR* H U S T O N BL ADDRESSEE COPYEEi REPORT 5 DOCUMENT 1116 c / 03/04/80 AUTHOR: ADDRESSEE! COPYEE! DOW DOW BUMB RR CHAMBERLIN RS CRUMMETT WB FISCHBACK BC GEHRING PJ HANSON RG JANTZ OK KENAGA EE MCKENNON KR NORRIS MG PRUITT ME SINCLAIR TD WATSON AJ DOW REGISTRATION GROUP LETTER 2 REPORT WESELOH JH ASHLEY JH BU RGE SS KL CHARLTON RW DAVIDSON JH FISCHER AC GETZENDANER ME HEFNER RE JENS EN DJ KOCIBA RJ MOOLENAAR RJ OREFFICE PF R O O K E DL THEIS JM WILLIAMS CS GORING CA SCRIVEN JG DOCUMENT 1117 01/00/80 REPORT 4 AUTHOR: DOW ADDRESSEE' COPYEE: / SUSKIND RR DOCUMENT 1118 v/ 00/00/53 AUTHOR: BISKIND MS ADDRESSEE: COPYEE-- (fe. cn <1 REPORT 1 AM JOUR OF DIGESTIVE TITLE PAGE 161 DEGRADATION OF 245T BY MICROORGANISMS (760000 MEETING HSSA 760203 TO 760205). SIKKA HC SYRACUSE UNIV RES 24D FACT SHEET. IDENTIFICATION OF THREE NEUTRAL CONTAMINANTS IN PRODUCTION GRADE 24D(JOUR OF AG & FOOD CHEM 20(3), 724-726). 245T AND SILVEX DEFENSE. BLAIR EH BUZELLI DT COOK RR DISHBURGER HJ FLANNERY RF GOODMAN C HOLDER BB JOHNSON JE LUOMA EV MOSS RD OSBORNE DM SCHMETZ BA VENABLE J MOODS CD HOERGER FD TUCKER MD BRAUN MH CASTILLO L C O U L T E R LL DONALDS JE FRAYER DR HANES JH HUNTER RC JONES J MCCOLLISTER MUELDER MM PRIDDY JK SHADOFF LA VRANISH SR DD LENG ML THE MORTALITY EXPERIENCE OF MORKERS EXPOSED TO TETRACHLORODIBENZODIOXIN IN A TRICHLOROPHENOL PROCESS ACCIDENT JOUR OF OCCUPATIONAL MEDICINE 22(1), 11-14). ZACK JA EXCERPTS FROM PUBLIC HEALTH ASPECTS OF THE NEM INSECTICIDES (AM JOUR OF DIGESTIVE DISEASES 20(11), 331-335). DIS NUMBER DATE DOCUMENT 1119 00/00/50 AUTHOR) WILLIAMS & WILKINS ADDRESSEE COPYEE) / TYPE REPORT PAGES 1 TITLE PAGE 162 245T ON CHILDREN {CLINICAL TOX OF COMMERCIAL PRODUCTS, 3RD EDITION, THERAPEUTICS INDEX, 8 0 H W I L L I A M S 8 WILKINS) C T T L . DOCUMENT 1120 V 00/00/68 AUTHOR: BIONETICS ADDRESSEE) COPYEE) DOCUMENT 1121V 00/00/50 AUTHOR) DRILL VA ADDRESSEE) COPYEE) NEWS 3 WHITESIDE T E X C E R P T S F R O M T H E B I O N E T I C S R E P O R T ( F R O M V O L U M E 3, E V A L U A T I O N OF THE TERATOGENIC ACTIVITY OF SELECTED PESTICIDES AND INDUSTRIAL CHEMICALS IN RATS AND MICE) (DEFOLIATION). REPORT 12 ACUTE AND SUBACUTE ORAL T O X ICITY OF 245T FOR DOGS. WAYNE UNIV COL OF MEDICI DOCUMENT 1122 y / 00/00/50 AUTHOR: MCCOLLISTER DD ADDRESSEE COPYEE: ^ REPORT ROWE VK 5 THE ACUTE ORAL TOXICITY OF 245T TO RATS, MICE, GUINEA PIGS CHICKS. SPENCER HC DOW DOCUMENT 1123 AUTHOR: DOW ADDRESSEE: COPYEE- 08/00/50 DOCUMENT 1124 AUTHOR: DOW ADDRESSEE: COPYEE: X .0 8 / 0 0 / 5 0 REPORT REPORT 5 RESULTS OF TOXICOLOGICAL TESTS ON 245T. 1 RESULTS OF TOXICOLOGICAL TESTS ON 245T. DOCUMENT 1125v' 00/00/50 AUTHOR: ZISCHKALE M ADDRESSEE COPYEE: NEWS 4 EFFECTS OF ROTENONE AND SOME COMMON HERBICIDES ON FISH FOOD ORGANISMS (FIELD & LABORATORY). REPORT SOUTHERN METHODIST UNIV DOCUMENT 1126'/ 00/00/60 AUTHOR: BODENSTEIN G ADDRESSEE: COPYEE: OT 00 NEWS 2 REPORT MULLERBASTGEN G UNTERSUCHUNGEN UBER DIE TOXIZITT EINIGER HERBIZIDE FR FISCHE. BOEHRINGER 8 SOHN NUMBER / DATE DOCUMENT 1127 V 11/00/53 AUTHOR R U D D 1RL ADDRESSEE COPYEE DOCUMENT 1128 12/00/62 AUTHOR: LAWRENCE JM ADDRESSEE: COPYEE DOCUMENT 1129 AUTHOR SNYDER ADDRESSEE: COPYEE: 00/00/65 DOCUMENT 1130 01/01/64 AUTHOR: CLARK DE ADDRESSEE: COPYEE: DOCUMENT 1131 AUTHOR: CLOFT ADDRESSEE COPYEE: DOW SMITH 12/16/54 HF H DOCUMENT 1132 00/00/50 AUTHOR: DRILL VA ADDRESSEE: COPYEE: DOCUMENT 1133 AUTHOR: DOW ADDRESSEE COPYEE: 08/00/50 TYPE PAGES NEWS 4 REPORT UC DAVIS REPORT 135 AUBURN UNIV REPORT OYEN F 110 NEWS REPORT HUNT LM 6 ROC DOW BENDALL T 1 REPORT 12 WAYNE ST UNIV REPORT 5 S S C h -T cn co .TITLE PAGE 163 FIELD REPORTING OF SUSPECTED WILDLIFE POISONING BY AGRICULTURAL CHEMICALS. AQUATIC HERBICIDE DATA. USDA DATA FROM 1 YEAR, 18 MONTH AND 2 Y E A R KUROSOL SL FEEDING STUDIES IN RATS CTTL. BUERGE JF MCKENNON J TOXICOLOGICAL EFFECTS OF SILVEX ON YEARLING CATTLE (J.A.V.M.A. 144(7) 750-755). PAMER JS ESTERON 245 (SALESMANS CALL REPORT H L U C A S TREE EXPERT COMPANY). LAWRENCE AA ROHE VK ACUTE AND SUB ACUTE ORAL TOXICITY OF 245T FOR DOGS (WAYNE ST UNIV). RESULTS OF TOXICOLOGICAL TESTS ON 245T (DOW) NUMBER DOCUMENT 1134 DATE 00/00/68 TYPE LEGAL PAGES 15 AUTHOR BAYLEY ND ADDRESSEE WELLFORD H COPYEE DOCUMENT 1135 AUTHOR ADDRESSEE COPYEE 00/00/69 DOCUMENT 1136 10/29/68 AUTHOR DOW ADDRESSEE COPYEE DOCUMENT 1137 03/00/65 AUTHOR DUNHAM RS ADDRESSEE COPYEE DOCUMENT 1138 AUTHOR ADDRESSEE COPYEE 00/00/60 DOCUMENT 1139 09/07/67 AUTHOR DOW ADDRESSEE COPYEE DOCUMENT 1140 AUTHOR DOW ADDRESSEE COPYEE 00/00/53 $ S' 03 O HARDIN CM CHART REPORT LENG ML NEWS USDA ARS NEWS REPORT WARREN LE REPORT HYMAS 1 9 12 3 23 TITLE PAGE 164 STATEMENT OF THE REASONS UNDERLYING THE DECISION OF THE SECRETARY WITH RESPECT TO THE REGISTRATIONS OF PRODUCTS CONTAINING 245T (ON PETITION FOR REVIEH OF AN ORDER OF THE SECRETARY OF AG) HARRISON W E L L FORD, ET A L . V. C L I F F O R D M. H A R D I N IN T H E U.S. C O U R T OF A P P E A L S FOR THE DISTRICT OF COLUMBIA CIRCUIT. USDA PRESENCE OF CHLORACNEGEN AND TCDD IN 245T FROM VARIOUS MANUFACTURERS. KURON SILVEX) REGISTRATION STATUS REPORT (USE OF SILVEX IN PASTURE AND RANGELAND. REQUEST FOR EXTENSION OF ALL REGISTRATIONS SUBMITTED BY NACA INDUSTRY TASK FORCE FOR PHENOXY HERBICIDE TOLERANCES). LYNN GE MCCOLLISTER DD HERBICIDE MANUAL FOR NONCROPLAND HEEDS (AG HANDBOOK 269 USDA). REDUCTION OF HAZARD BY CONTROL OF TOXICITY. RESIDUES OF HERBICIDES AND IMPACT ON USES BY LIVESTOCK (FOR PRESENTATION AT THE FOREST, RANGE NONCROPLAND HERBICIDE SYMPOSIUM OR ST U N I V S E P T E M B E R 7 T H R O U G H 9, 1967). A C U T E STUDIES (STATEMENT 2). ROWE VK NUMBER DOCUMENT 1141 AUTHOR: PALMER ADDRESSEE COPYEE: DATE 00/00/69 DOCUMENT 1142 04/06/61 AUTHOR: BUCEK OC ADDRESSEE: COPYEE: DOW . HAAGSMA TA I JFK I KWM I TRN DOCUMENT 1143 AUTHOR USDI ADDRESSEE: COPYEE: 00/00/62 DOCUMENT 1144 AUTHOR DOW ADDRESSEE COPYEE: HOWE 05/05/59 DOCUMENT 1145 AUTHOR: ADDRESSEE: COPYEE: 00/00/69 DOCUMENT 1146 10/00/51 AUTHOR: KRATOCHVIL DE ADDRESSEE COPYEE: DOCUMENT 1147 00/00/58 AUTHOR: RADELEFF RD ADDRESSEE: COPYEE: TYPE NEWS RADELEFF PAGES 2 REPORT DOW BARRONS I APB I JS I PDL JOHNSON KC JE 17 REPORT 4 REPORT NATION HA 5 REPORT 18 NEWS 5 REPORT ST COL OF AG SD REPORT USDA 12 lS C h - & H-* CD TITLE 245T. PAGE 165 PROPYLENE GLYCOL, SILVEX, 24D OR 245T FOR FATTENING BEEF CATTLE (DON REPORT TA-176). BLAIR EH I CMS I JNB I RMI LYNN GE BRITTON I CRI I JNV I RPP ROWE VK EC EFFECTS OF PESTICIDES ON FISH AND HILDLIFE A REVIEW OF INVESTIGATIONS DURING 1960 (FISH 8 WILDLIFE SERVICE CIRCULAR 143). RESULTS OF HERBICIDE SCREENING TESTS AGAINST CERTAIN AQUATIC HEEDS AND FISH. SOME SALIENT ASPECTS OF 245T TOXICOLOGY, METABOLISM AND DISSIPATION REACTION OF THE ENVIRONMENT. DETERMINATION OF THE EFFECT OF SEVERAL HERBICIDES OH SOIL MICROORGANISM (WEEDS 1(1),25-31). THE TOXICITY OF INSECTICIDES AND HERBICIDES TO LIVESTOCK ADVANCE VET SCI 4, 265-276). NUMBER DATE DOCUMENT 1148 00/00/59 AUTHOR* LHOSTE J ADDRESSEE) COPYEE: TYPE REPORT PAGES 7 DOCUMENT 1149 00/00/62 REPORT 6 AUTHOR! DAVIS JT ADDRESSEE! COPYEE: HUGHES JS DOCUMENT 1150 00/00/65 AUTHOR! GOLDBERT HS ADDRESSEE COPYEE: ABSTRACT GOODMAN RN 1 DOCUMENT 1151 09/00/55 NEWS 5 AUTHOR! COLMER AR ADDRESSEE: COPYEE! LA ST UNIV DOCUMENT 1152 08/00/58 NEWS AUTHOR: CHESTERFORD PARK RES STA EDSON EF ADDRESSEE! COPYEE-* 3 DOCUMENT 1153 11/25/67 AUTHOR! GALSTON AW ADDRESSEE! COPYEE: NEWS REPORT YALE UNIV 3 DOCUMENT 1154 00/00/65 NEWS AUTHOR! ADDRESSEE! COPYEE: REPORT INST OF WATER EARTH AND KAYSER H 14 tSh jin i<4 05 O TITLE PAGE 166 THE REPERCUSSIONS ON THE AQUATIC FAUNA DUE TO THE USE OF CHEMICAL WEED KILLERS (FEVRIER). COMPARATIVE TOXICITY TO BLUEGILL SUNFISH OF GRANULAR AND LIQUID HERBICIDES (PROCEEDINGS OF THE SIXTEETH ANNUAL CONFERENCE SE ASSN OF GAME AND FISH COMMISSIONERS). LA WILD LIFE FISHERIES C INFLUENCE OF 2A5T ON STAPHYLOCOCCAL PENICILLINASE (JOUR BACTERIOLOGY 89(6), 1621-1622). KUCERA LS THE EFFECT OF HERBICIDES ON SOIL MICROORGANISMS (THE EFFECT OF SOME HERBICIDES ON THE RESPIRATION OF AZOTOBACTER (APPLIED MICROBIOL 3(5), 288-292). MAGEE LA THE RISKS OF PESTICIDES TO FISH (WORLD CROPS). HERBICIDES IN VIETNAM (THE NEW REPUBLIC). CONTRIBUTIONS TO THE TOXICITY OF HERBICIDES TO THE WATER-LIFE C O M M U N I T Y PA R T I, FISH (DAS G A S - U N D W A S S E R F A C H 106(8), 2203). LUEDEMANN D NUMBER DATE DOCUMENT 1155 00/00/69 AUTHORi HILTIBRAN RC ADDRESSEE COPYEE TYPE PAGES ABSTRACT 1 IL NAT U R A L H I S T O R Y DOCUMENT 1156 00/00/61 AUTHOR GRIEPENTROG F ADDRESSEE COPYEE NEWS REPORT 12 DOCUMENT 1157 00/00/62 NEWS 22 AUTHOR BANDT HJ ADDRESSEE COPYEE REPORT NEHRING D DOCUMENT 1158 08/01/6A AUTHOR BOUNDS HC ADDRESSEE COPYEE REPORT COLMER AR 3 DOCUMENT 1159 00/00/62 ABSTRACT 1 AUTHOR ADDRESSEE COPYEE ANDERSSON A WADNE C DAHL S DOCUMENT 1160 05/00/52 AUTHOR ONTARIO AG COLL ADDRESSEE COPYEE DOCUMENT 1161 00/00/59 NEWS REPORT SMITH MV ABSTRACT 1 2 AUTHOR FISH CULTURE RES INST ADDRESSEE C O P Y E E _ PROWSE GA > cn> GO TITLE PAGE 167 OXYGEN AND PHOSPHATE UPTAKE BY BLUEGILL LIVER MITOCHONDRIA IN THE PRESENCE OF VARIOUS PHENOXY COMPOUNDS CWSSA ABSTRACT 27). SURVE A FEW PLANT PROTECTION AGENTS AS EXAMPLES OF WEAK ALLERGENS (MEDIZIN UND ERNHRUNG 2(5) 106-8). INJURIOUS EFFECT AND USE OF HERBICIDES IN FISHERIES (TAGUNGSBERICHT, DEUTSCHE AKADEMIE DER LANDWIRTSCHAFTSWISSENSCHAFTEN, BERLIN 54, 45-58). SCHLTER M RESISTANCE OF STREPTOMYCES TO HERBICIDES (THE SUGAR BULLETIN). LA AG EXP STATION THE TOXICITY OF SOME HERBICIDES TO CHICKS (KGL LANTBRUKSHOOSKOL OCH STATENS LANTBRUKSFORSOK, STATENS HUSDJURSFORSOK, SARTRYCK OCH FERHANDSMEDD 155, 1 8 H C H E M ABSTRACT 59, 5548). INST TECH STOCKHOLM KIVIMAE A WEED KILLING SPRAYS VS BEES (CANADIAN BEE JOUR 60(5), 16-17). NOTES ON THE TOXICITY TO FISH OF SOME COMMON AGRICULTURAL INSECTICIDES AND WEEDICIDES (PEST ABSTRACTS AND NEWS SUMMARY A5 (4), 508-509). NUMBER DOCUMENT 1162 DATE 12/14/67 TYPE NEWS PAGES 4 AUTHOR DAVIS GRF ADDRESSEE: COPYEE: REPORT DEPT OF AG CAN DOCUMENT 1163 00/00/64 AUTHOR: COPE OB ADDRESSEE COPYEE: REPORT 13 FISH-PEST RES LAB DOCUMENT 1164 AUTHOR ADDRESSEE COPYEE: 00/00/63 CHART 16 DOCUMENT 1165 00/00/50 AUTHOR: DRILL VA ADDRESSEE COPYEE: REPORT MAYNE UNIV 11 DOCUMENT 1166 AUTHOR: DOM ADDRESSEE: COPYEE: 08/00/50 REPORT 6 DOCUMENT 1167 00/00/56 REPORT AUTHOR: DEPT FISH 8 GAME CA GENELLY RE ADDRESSEE: COPYEE: 3 DOCUMENT 1168 02/18/63 AUTHOR DAVIS JT ADDRESSEE: COPYEE: CHART REPORT HUGHES JS 4 DOCUMENT 1169 08/00/68 AUTHOR: ADDRESSEE: COPYEE: BIONETICS KOTIN P ABSTRACT 4 CHART BRL NATL CANCER INST TITLE PAGE 168 EFFECTS OF 24D, MALEIC ACID HYDRAZIDE, AND 245T ON SURVIVAL AND GROWTH OF THE PRAIRIE GRAIN WIREWORM, CTENICERA DESTRUCTOR BROWN (COLEOPTERA, ELATERIDAE) (CANADIAN JOUR OF ZO O L O G Y 46, 747-750). SPORT FISHERY INVESTIGATIONS. TOXICITY TESTS OF SELECTED CHEMICALS AT PATUXENT, 1963 (97112). ACUTE AND SUBACUTE ORAL TOXICITY OF 245T FOR DOGS. RESULTS OF TOXICOLOGICAL TESTS ON 245T. HERBICIDES 24D (PESTICIDES AND WILDLIFE). RUDD RL UC DAVIS MEDIAN TOLERANCE LIMITS REPORTED IN PARTS PER MILLION OF BLUEGILL SUNFISH TO HERBICIDES TESTED DURING 1961-62. LA WILD LIFE 8 FISHERIES EVALUATION OF CARCINOGENIC, TERATOGENIC 8 MUTAGENIC ACTIVITIES OF SELECTED PESTICIDES AND INDUSTRIAL CHEMICALS. FALK H NIH HART ER PALOTTA AJ NUMBER DATE DOCUMENT 1170 05/00/57 AUTHOR: SIMON J ADDRESSEE: COPYEE: TYPE REPORT SUND JM PAGES 2 DOCUMENT 1171 AUTHOR: DOM ADDRESSEE COPYEE: DOM I JFK I TAH 08/12/60 ABSTRACT REPORT RAPER JT I CMS I JS I WRM 18 DOCUMENT 1172 AUTHOR DOM ADDRESSEE DOM COPYEE: 08/25/45 REPORT MODARNS C ALLEN MN 9 DOCUMENT 1173 04/25/67 AUTHOR: DOM ADDRESSEE: DOM COPYEE: DOM STAEHLING EC LETTER HIDIGER A COULTER KE BENDER SL 4 DOCUMENT 1174 05/25/65 AUtHOR: BROHN MT ADDRESSEE' COPYEE: DOM FALKENSTEIN HJ KAGY JF NORTON TR REPORT DOH BARRONS KC GORDON HL KILIAN DJ MILSON AM 3 DOCUMENT 1175 AUTHOR: DOM ADDRESSEE: COPYEE: 10/26/54 REPORT 11 MCCOLLISTER DD DOCUMENT 1176 12/13/63 LETTER 2 AUTHOR: DOM ROHE VK ADDRESSEE: MANUFACTURING CHEMISTS A STEPHENSON FG COPYEE: DON ROWE VK 50 H-4* 05 en TITLE PAGE 169 HEEDS CONTAINING NITRATES CAUSE ABORTION IN CATTLE (AGRONOMY JOUR <9(5), 278-279). UNIV OF HI HRIGHT MJ ADDITION OF HERBICIDES OR VERSENES TO BROILER FEEDS. I GEL I KCB I JEJ I RPP T O X I C I T Y OF 2<t5T. ROHE VK VEAZEY HR CHLORACNE RESEARCH PROGRAM. HABERSTROH HH SAUERS RC RESULTS OF A THO Y EAR D I ETARY FEEDING S T U D Y IN DOGS OF KUROSAL SL (POTASSIUM SALT OF SILVEX). MCCOLLISTER DD HHITE LC BOUNDY RH HAKE CL LYNN GE ELSHERE D JOHNSTON RV MULLISON HR RESULTS OF ACUTE AND SEMICHRONIC ORAL TOXICITY TESTS HITH RATS FED SILVEX OR 2(2<i5-TRICHL0R0PHEN0XY) PROPIONIC ACID. ROHE VK REPLY ON INFORMATION ABOUT THE SAFETY IN THE MANUFACTURE OF 245-TRICHLOROPHENOL CTTL. HOYLE HR MCCUTCHEN S NUMBER DATE DOCUMENT 1177 12/06/61 AUTHOR: DOW A D D R ESSEE LO H E JI COPYEE: DON DOCUMENT 1178 AUTHOR: DOW ADDRESSEE COPYEE 02/18/58 DOCUMENT 1179 11/28/61 AUTHOR: DOW ADDRESSEE L O W E JI COPYEE DOCUMENT 1180 AUTHOR: DOW ADDRESSEE: DOW COPYEE: DOW 06/27/62 DOCUMENT 1181 07/00/66 AUTHOR: MEAGHER WR ADDRESSEE: COPYEE: DOCUMENT 1182 00/00/68 AUTHOR: LEE YN ADDRESSEE: COPYEE: DOCUMENT 1183 00/00/66 AUTHOR UC DAVIS ADDRESSEE: COPYEE1 Vi vT So 05 O' 05 p TYPE PAGES LETTER 1 RITTY PM USD1 C O U L T E R LL I MEMO 2 LETTER RITTY PM USDI LETTER 1 RITTY PM WINSTON AW JR KORSMEIER RB REPORT 5 TEST UNI V OF FL REPORT TEST LUH BS 6 REPORT 5 TITLE PAGE 170 I NERT I N G R E D I E N T R E Q U E S T DENIED, FI S H TOXICITY DATA SENT INSTEAD CTTL. SAUNDERS ES HINSTON B TOXIC EFFECTS OF 24D, 245T, MCP, 245T ETHANOL AND DALAPON CTTL. INERT INGREDIENT REQUEST DENIED, FISH TOXICITY DATA SENT INSTEAD CTTL. ATTACHED REPORT ON FISH TOXICITY CTTL. WILTSE M DETERMINATION OF 24D AND 2-(245-TRICHL0R0PHEN0XY)PR0PI0NIC ACID IN CITRUS BY ELECTRON CAPTURE GAS CHROMATOGRAPHY (AG & FOOD CHEM 14(4), 3 7 4 - 3 7 7 ) ( T A 0 5 .01 . P 4 H P P 8 F 0 6 6 9 ) . EFFECT OF CHLOROPHENOXYACETIC ACID GROWTH REGULATOR SPRAYS ON RESIDUES IN C A N N E D APRI C O T S AND G R A P E S (JOUR OF FOOD SCIE N C E 33, 104-108)(TA50.01.P4MPP8F0669). UC DAVIS 660000 ANNUAL REPORT RESIDUE PROGRAM OF THE AGRICULTURAL, T O X I C O L O G Y AND R E S ID UE RES E A R C H LABORATORY, UC D A V I S ( T A 5 0 .0 1 .P4) (P P 8 F 0 6 6 9 ). NUMBER DOCUMENT 1184 DATE 09/00/67 TT PE REPORT PAGES AUTHOR: FISHBEIN L ADDRESSEE COPYEE: ZIELINSKI DOCUMENT 1185 06/06/68 AUTHOR: CORNELL ADDRESSEE DOM COPYEE: LETTER LISK DJ LENG ML DOCUMENT 1186 00/00/62 REPORT AUTHOR CRAFTS AS UNIV OF IL ADDRESSEE: COrYEE: KEY JL YAMAGUCHI DOCUMENT 1187 00/00/66 REPORT AUTHOR MORTON HL ADDRESSEE COPYEE: USDA ARS DOCUMENT 1188 00/00/68 REPORT AUTHOR DAVIS FS TX ASM ADDRESSEE COPYEE TEST DOD USDA ARS DOCUMENT 1189 AUTHOR: DOM ADDRESSEE: COPYEE: 09/12/68 REPORT LENG ML ^h-cr DOCUMENT 1190 06/00/66 REPORT AUTHOR BUR OF COMMERCIAL FISHER BUTLER PA ADDRESSEE COPYEE: .rf* H"* i OE5 <1 12 TITLE PAGE 171 GAS CHROMATOGRAPHIC MEASUREMENT OF DISAPPEARANCE RATES OF 24D AND 245T AND 240 ESTERS IN MICE (JOUR AG FOOD CHEM 15(5), 8 4 1 - 8 4 4 H T A 5 0 . 01 . P 4 H P P 8 F 0 6 6 9 ) . MISTAKE IN CALCULATIONS OF KURON IN COH FEEDING STUDY CONFIRMED (TA50.01.P4)(PP8F0669) C T T L . PENETRATION, TRANSLOCATION, AND METABOLISM OF 24D AND 245T IN MILD AND CULTIVATED CUCUMBER PLANTS (WEEDS 10, 29-35) (TA50.01.P4)(PP8F0669). SLIFE FW UC DAVIS INFLUENCE OF TEMPERATURE AND HUMIDITY ON FOLIAR ABSORPTION, TRANSLOCATION, AND METABOLISM OF 245T BY MESQUITE SEEDLINGS (HEEDS 14, 1 3 6 - 1 4 1 M T A 5 0 . 01.P 4 ) ( P P 8 F 0 6 6 9 ) . RADIOISOTOPIC AND GAS CHROMATOGRAPHIC METHODS FOR MEASURING A B S O R P T I O N A N D T R A N S L O C A T I O N O F 2 4 5 T B Y M E S Q U I T E ( W EED S C I E N C E 16, 88-91 )(TA50.01.P4XPP8F0669) . MERKLE MG MORTON HL REVIEW ON THE METABOLISM OF PHENOXY COMPOUNDS IN PLANTS AND ANIMALS (SUMMARY STATEMENT)(PP8F0669)(TA50.01.P3). COMMERCIAL FISHERIES INVESTIGATIONS (PESTICIDE WILDLIFE STUDIES, A REVIEW OF FISH AND WILDLIFE SERVICE INVESTIGATIONS, CIRCULAR 167). HUMBER DOCUMENT 1191 AUTHOR: DOW ADDRESSEE: COPYEE: DOCUMENT 1192 AUTHOR: DOW ADDRESSEE: COPYEE: DOCUMENT 1193 AUTHOR: DOW ADDRESSEE: COPYEE: DOCUMENT 1194 AUTHOR: DOW ADDRESSEE: COPYEE: DOCUMENT 1195 DATE 11/27/61 TYPE REPORT PAGES 9 08/00/50 REPORT A 00/00/50 REPORT 6 MCCOLLISTER DD 00/00/60 REPORT WILTSE MO 6 09/26/67 LETTER 2 AUTHOR: BEUTEL AP ADDRESSEE: KRATZ WG COPYEE: DOW DOCUMENT 1196 02/15/61 DOW US ARMY STAEHLING EC LETTER 3 AUTHOR: ID EXP STATION ADDRESSEE: USDA COPYEE: HALLER HL DOCUMENT 1197 00/00/53 AUTHOR: DRILL VA ADDRESSEE: COPYEE: VERNER L HARD JC YOST G NEWS REPORT HIRATZKA T 3 05 00 TITLE PAGE 172 RESULTS OF 90 DAY DIETARY FEEDING STUDIES OF DOHANOL 97B ESTER 245T IN RATS. RESULTS OF TOXICOLOGICAL TESTS ON 245T. THE ACUTE ORAL TOXICITY OF 245T TO RATS, MICE, GUINEA PIGS AND CHICKS. ROWE VK SPENCER HC AQUATIC VEGETATION CONTROL WITH KURON (PRESENTED AT 600000 MEETING OF THE WSA DENVER CO). DOW'S DECISION NOT TO BID ON THE U.S. ARMY'S REQUEST FOR PROPOSAL DACA41-68-R-0001, FOR THE DESIGN, CONSTRUCTION AND OPERATION OF AN 8 MILLION GALLON PER YEAR HERBICIDE ORANGE PLANT AT WELDON SPRING, MO CTTL. WHITESELL RA YANKA DE RESIDUE ANALYSES OF EARLY ITALIAN PRUNES SPRAYED WITH 245TP (TAKEN FROM SALMON SECTION OF APPLICATION FOR REGISTRATION OF COLOR SET (USDA REG 464-267) FOR USE ON PRUNES, SUBMITTED TO PEST REGULATION DIV BY DOW ON 610525). TOXICITY OF 24D AND 245T(A REPORT ON THEIR ACUTE AND CHRONIC T O X I C I T Y IN D O G S ) ( I N D U S T R I A L H Y G I E N E A N D O C C U P A T I O N A L M E D I C I N E 7, 61-63). WAYNE UNIV NUMBER DOCUMENT 1198 AUTHOR DOM ADDRESSEE COPYEE DATE 00/ 00/68 DOCUMENT 1199 00/00/69 AUTHOR MINTZ M ADDRESSEE COPYEE DOCUMENT 1200 12/03/64 TYPE PRESENT NEWS LETTER PAGES 23 1 1 AUTHOR HEM ADDRESSEE' COPYEE DOCUMENT 1201 04/07/69 AUTHOR CHEM ENGINEERING ADDRESSEE COPYEE DOCUMENT 1202 AUTHOR: ADDRESSEE: COPYEE: 00/00/65 DOCUMENT 1203 AUTHOR: DOM ADDRESSEE: DOW COPYEE: 10/05/67 DOCUMENT 1204 08/26/64 AUTHOR: DOM ADDRESSEE: COPYEE: PUB HEALTH SERV NEMS REPORT 8 REPORT 4 LETTER 1 SILVERSTEIN LG FERNANDEZ JB CHART MINUTES REPORT HOLMES R 7 02 CO TITLE PAGE 173 DOM EXPERIENCE 640000 TO P R E S E N T (CHLORACNE) AND BRIEF MENTION OF INCIDENCES IN FRANCE AND GERMANY C T T L . WIDELY USED HERBICIDE TIED TO BIRTH DEFECTSiTHE WASHINGTON POST). ALTHOUGH CLAIMS HAVE BEEN MADE THAT LIVER AND SKIN TOXICITY IS DUE TO T C D D R A T H E R T H A N 245T, NO C O N C L U S I V E E V I D E N C E OF THIS IS AVAILABLE SINCE NO ONE HAS SEPARATED THE VARIOUS COMPOUNDS PRESENT IN COMMERCIAL 245T CTTL. PESTICIDES, PRESENT AND FUTURE (CHEM ENGINEERING, 133-140). SUMMARY OF TOXICOLOGICAL AND ANALYTICAL INFORMATION ON THE CHLORACNEGEN IMPURITY FOUND IN SOME SAMPLES OF 245T. CHLORACNE AT THOMPSON HAYHARD COMPANY. MEETING DISCUSSIONS INCLUDE CHLORACNE TREATMENT, CAUSE, PLANS FOR CLEANUP CTTL. OLSON KJ NUMBER DOCUMENT 1205 DATE 11/27/67 AUTHOR: DUNN CL ADDRESSEE HAYS H COPYEE: ANDERSON1 RJ DOCUMENT 1206 04/16/68 AUTHOR FDA ADDRESSEE: DUNN CL COPYEE: USDA ARS DOCUMENT 1207 07/11/68 AUTHOR: DUNN CL ADDRESSEE: BAKER: DM JR COPYEE- USDA DOCUMENT 1208 10/29/68 AUTHOR: DUNN CL ADDRESSEE HAYS H COPYEE: D A N I E L S O N LL DOCUMENT 1209 00/00/66 AUTHOR HUNT LM ADDRESSEE: COPYEE: DOCUMENT 1210 00/00/64 AUTHOR: CLARK DE ADDRESSEE: COPYEE: DOCUMENT 1211 07/00/68 AUTHOR: DOW ADDRESSEE COPYEE: h * O TYPE PAGES TITLE PAGE 174 LETTER NACA IND TASK USDA D A N I E L S O N LL 2 FORCE REQUEST FOR EXTENT10N OF CANCELLATION OF REGISTRATION FOR USE OF PHENOXY HERBICIDE, 24D, 245T, MCPA, AND SILVEX, FOR AT LEAST ONE YEAR BEYOND 671231 CTTL. ON P IRVING GW USDA ARS LETTER HEW NACA IND TASK 2 FORCE REASONS FOR FDA REQUESTED IN PP STOKES W ON P REFUSAL TO ESTABLISH 8F0675 CTTL. TOLERANCES FOR SILVEX LETTER NACA FDA 2 LETTER REGARDING MEETING WITH NACA, USDA, AND DOW CONCERNING PESTICIDE PETITION 8F0669 (245T), 8F0670 (24D), 8F0675 (SILVEX), AND 8F0676 (MCPA), AND ADDING A SECTION FOR THE PETITION REVIEWING SCIENTIFIC LITERATURE WITH RESPECT TO METABOLISM OF PHENOXY HERBICIDES AND EMPHASIZING THE APPLICATION TO RESIDUES CTTL. HEW LETTER REPORT NACA USDA USDA ARS REPORT PALMER JS 11 5 EXTENSIONS OF REGISTERED USES OF 24D, 245T, MCPA, AND SILVEX (P P 8 F 0 6 7 5) CTTL. PRELIMINARY STUDY ON TOXICOLOGIC AND BIOCHEMICAL EFFECTS OF SILVEX ON SHEEP (AM JOUR OF VETERINARY RES 27(116), 172-176) (S A 5 0 .00.01.P I )(PP8F0675). USDA ARS WRIGHT FC REPORT HUNT LM 7 TOXICOLOGICAL EFFECTS OF SILVEX ON YEARLING CATTLE (JOUR OF AM VETERINARY MEDICAL ASSOC 144(7), 750-755)(SA50.00.01.PI) (PP8F0675) PALMER JS USDA REPORT LENG ML 2 REVIEW ON THE METABOLISM OF PHENOXY COMPOUNDS IN PLANTS AND ANIMALS (TAKEN FROM AMENDMENT TO PP 8F0675 FOR SILVEX, SUBMITTED 680900)(SA50.00.P1). NUMBER DOCUMENT 1219 AUTHOR: DOW ADDRESSEE' COPYEE: DATE 11/03/67 DOCUMENT 1220 11/00/62 AUTHOR: DOW ADDRESSEE COPYEE: DOCUMENT 1221 09/00/67 AUTHOR: DUGGAN RE ADDRESSEE: COPYEE: DOCUMENT 1222 02/00/50 TYPE REPORT PAGES 6 REPORT MESLER RJ 10 NEWS REPORT FDA 5 NEWS 8 AUTHOR: ADDRESSEE: COPYEE: AG EXP STATION MI MI ST COLLEGE REPORT BELDING RC DOCUMENT 1223 00/00/62 REPORT AUTHOR: BUR OF SPORT FISHERIES 8 DEWITT JB ADDRESSEE' COPYEE: 5 DOCUMENT 1226 AUTHOR: BUR OF GEORGE ADDRESSEE: COPYEE: 00/00/60 REPORT SPORT FISHERIES S CRAB JL TREE DG 7 DOCUMENT 1225 00/00/62 REPORT AUTHOR: BUR OF SPORT FISHERIES & COPE OB ADDRESSEE: COPYEE: 5 -C SO CT' ro TITLE PAGE ACUTE ORAL, SKIN, EYE AND INHALATION STUDIES:.1.1.1.0) (PA50.01.PI)(PP8F0660)(TORDON) CTTL. 176 7. R E S U L T S OF 6 1 0 0 0 0 A N D 6 2 0 0 0 0 F I E L D T E S T S H I T H T O R D O N IN M I C H I G A N (IN SUPPORT OF REQUEST OF REGISTRATION OF TORDON 101 M I X T U R E ) ( P A 2 .08.S I ). MATSON AJ DIETARY INTAKE OF PESTICIDE CHEMICALS (SCIENCE 157(3792), 1006-1010)(DA50.02.P0)(PP 8F0760). WEATHERWAX JR SOME EFFECTS OF HERBICIDES ON PASTURE AND ON GRAZING LIVESTOCK (MI AG EXP STATION QUARTERLY BULLETIN 32(3), 378-385) (DA50.02.P0)(PP 8F0670). FARWELL ED GRIGSBY BH WILDLIFE STUDIES, PATUXENT WILDLIFE RES CENTER (DA50.02.P0) (PP 8F0670). SPRINGER PF STICKEL WH EFFECTS ON WILDLIFE (DA50.02.PO)(PP 8F0670). DEWITT JB FINLEY RB SPORT FISHERY INVESTIGATIONS (DA50.02.P0KPP 8F0670) NUMBER DOCUMENT 1226 DATE 10/00/54 TYPE NEMS PAGES 8 AUTHORi DOM ADDRESSEE! COPYEE: REPORT HYMAS TA DOCUMENT 1227 AUTHOR! DOM ADDRESSEE! COPYEE! 04/00/65 NEMS REPORT LYNN GE 3 DOCUMENT 1228 12/14/64 AUTHOR DELISLE NG ADDRESSEE: COPYEE: MEMO REPORT DOM 4 DOCUMENT 1229 AUTHOR DOM ADDRESSEE! COPYEE: 00/00/69 CHART 11 TECH FERNANDEZ JB DOCUMENT 1230 AUTHOR: DOM ADDRESSEE: COPYEE! 00/00/69 PRESENT 23 DOCUMENT 1231 12/23/68 LETTER AUTHOR: CH BOEHRINGER SOHN MGERM DOLL 0 ADDRESSEE DOM TRAPP MB COPYEE: 2 DOCUMENT 1232 01/14/65 AUTHOR: DOM ADDRESSEE: COPYEE: DOM GOERGEN G LUECK AF VAUARSDALE JD REPORT MIDIGER AH 3 MIDIGER AH HABERSTROH MH POFFENBERGER N TITLE PAGE 177 SUMMARY OF TOXICOLOGICAL INFORMATION ON 24D AND 2A5T TYPE HERBICIDES AND AN EVALUATION OF THE HAZARDS TO LIVESTOCK ASSOCIATED WITH THEIR USE (AM JOUR VETERINARY RES, 622-629) (DA50.02.P0HPP 8F0670). ROWE VK A REVIEW OF TOXICOLOGICAL INFORMATION ON TORDON HERBICIDES (DTE). CHLORACNE(NOTES PER LUECKHBOEHRINGER PROGIL). PHENOLIC BYPRODUCTS IN 2A5-TRICHL0R0PHEN0L DERIVED FROM IMPURITIES IN TETRACHLOROBENZENE. HABERSTROH WH CHLORACNE, DOW EXPERIENCE. 2A5-TRICHL0R0PHEN0L. 2A5-TRICHL0R0PHEN0L, PROPOSED INTERIM REACTOR. DELISLE NG HOLMES RD SAUERS RC DOEDENS JD HUTCHENREUTHER C TRAPP WB NUMBER DATE DOCUMENT 1233 08/16/66 AUTHOR ADDRESSEE COPYEE DOW DOW DOW ROWE VK TYPE PAGES LETTER 1 SILVERSTEIN LG HIGHHILL CA AMSTUTZ FC STAEHLING EC DOCUMENT 1234 AUTHOR ADDRESSEE COPYEE 00/00/64 NEWS 1 DOCUMENT 1235 05/23/56 REPORT 5 AUTHOR KIMMIG J ADDRESSEE COPYEE SCHULZ KH DOCUMENT 1236 06/00/66 REPORT AUTHOR: ADDRESSEE COPYEE D1V OF OCCUPATIONAL HEAL OAFA F ER WM 5 DOCUMENT 1237 00/00/66 REPORT 9 AUTHOR MENZEE CM ADDRESSEE COPYEE USDI DOCUMENT 1238 00/00/63 NEWS 5 AUTHOR ADDRESSEE COPYEE BUR OF COMMERCIAL REPORT FISHER BUTLER PA DOCUMENT 1239 00/00/63 NEWS 9 AUTHOR PALMER JS ADDRFS5EE COPYEE REPORT RADELEFF RD OL'Cb -, TITLE PAGE ANIMAL TEST WILL DETECT T H E P R E S E N C E OF CHLORACNE P R O D U C I N G COMPOUNDS CTTL. 178 CHASE FI WILSON AW HOLDER BB DOW HERBICIDE HISTORY TRACED. OCCUPATIONAL CHLORACNE CAUSED BY AROMATIC CYCLIC ETHERS (DERMATOLOGICA, 115, 5 4 0 - 5 4 6 H 2 3 R D CONGRESS OF GERMAN DERMATOLOGISTS VIENNA). UNIV CLINIC OF DERMATOLO OCCUPATIONAL DISEASES, HERBICIDES, A GUIDE TO THEIR RECOGNITION (PUB HEALTH SERV). HEW METABOLISM OF PESTICIDES CUSDI FISH AND WILDLIFE SERVICE, BUR OF SPORT FISHERIES AND WILDLIFE, SPECIAL SCIENTIFIC REPORT WILDLIFE 96, 6 1 - 6 9 M S E C T I O N C M E T A BOLISM)(TA50.01 ,P2 PP8F0669 671200). COMMERCIAL FISHERY INVESTIGATIONS, 5-8, 25PEST WILDLIFE STUDIES 630000)(A REVIEW OF FISH AND WILDLIFE SERVICE INVESTIGATIONS DURING THE CALENDAR YEAR, CIRCULAR 199, 6 4 0 8 0 0 H S E C T I O N C M E T A B O L I S M ) ( T A 5 0 . 01.P2 PP8F0669 671200). THE TOXICOLOGIC EFFECTS OF CERTAIN FUNGICIDES AND HERBICIDES ON SHEEP AND CATTLE (ANNALS NY ACADEMY OF SCIENCES, 729-736) (SECTION C METABOLISMMTA50.01.P2 PP8F0669 671200). USDA ARS NUMBER DOCUMENT 1240 AUTHOR! DON ADDRESSEE! COPYEE! DATE 08/00/50 TYPE REPORT PAGES 4 DOCUMENT 1241 AUTHOR! DOM ADDRESSEE! COPYEE: 00/00/50 * REPORT 6 MCCOLLISTER DD DOCUMENT 1242 12/08/67 REPORT 15 AUTHOR ADDRESSEE COPYEE: DOCUMENT 1243 04/00/69 AUTHOR CHANO MC ADDRESSEE' COPYEE: NEMS REPORT GOODIN JR 3 DOCUMENT 1244 00/00/68 NEMS 4 AUTHOR: MCCARTY MK ADDRESSEE: COPYEE REPORT SCIFES CJ DOCUMENT 1245 AUTHOR: ADDRESSEE! C O P Y E E '- 09/00/68 REPORT 6 DOCUMENT 1246 AUTHOR: DOM ADDRESSEE: LUCAS COPYEE: DOM SMITH 06/23/53 TREE EXPERT HL 'O i H-* n ) -vi OT LETTER ROME VK SICKMAN ML BENDALL T 1 TITLE PAGE 179 RESULTS OF TOXICOLOGICAL TESTS ON 245T (SECTION C TOXICOLOGY) CTA50.01.P2 PP8F0669 671200). THE ACUTE ORAL TOXICITY OF 245T TO RATS, MICE, GUINEA PIGS AND CHICKS (SECTION C T O X I C O L O G Y M T A 5 0 . 0 1 .P2 PP8F0669 671200). ROWE VK SPENCER HC FULL REPORTS OF INVESTIGATIONS MADE WITH RESPECT TO THE SAFETY OF THE PESTICIDE CHEMICAL, 245T (SECTION C ) ( T A 5 0 .01.P2 PP8F0669 671200). A NEW SELECTIVE BIOASSAY FOR TORDON IN HATER(DTE 24(9), 4-5 (P P 0 F 0 8 6 3 ) . UC RIVERSIDE SMOOTH BROMEGRASS RESPONSE TO HERBICIDES AS AFFECTED BY TIME OF APP L I C A T I O N IN RELATION TO N I T R O G E N F E R T I L I Z A T I O N W E E D S C I ENCE 16, 443-446)(PP0F0863). METABOLISM IN ANIMALS (DA50.02.01 . P 1MPP8F06 70) . SUGGESTED TREATMENT FOR ANY CHEMICAL CONTAMINATION OF THE EYE CTTL. CLOFT HF GAY HH NUMBER DATE DOCUMENT 1247 06/05/53 AUTHOR: BRYANT CA ADDRESSEE! DOM COPYEE! DOM TYPE PAGES LETTER DOM ROME VK SMITH HL 1 DOCUMENT 1248 06/07/54 AUTHOR JENKINS RE ADDRESSEE! DOM COPYEE: LETTER GAY HH 1 DOCUMENT 1249 04/12/54 LETTER AUTHOR: DOM ADDRESSEE: AG EXTEN SER PURDUE COPYEE: DOM GAY HH VANDEMARK JS ROME VK 1 DOCUMENT 1250 03/24/5!} LETTER AUTHOR: AG EXTEN SER PURDUE ADDRESSEE: DOM COPYEE: VANDEMARK JS ROME VK 1 DOCUMENT 1251 04/01/54 AUTHOR! C A S T R O IJ ADDRESSEE: DOM COPYEE: LETTER HI NATL PARK 1 DOCUMENT 1252 04/23/54 AUTHOR! DOM A D DRESSEE: C A S T R O IJ COPYEE: DOM LETTER ROME VK HI NATL PARK GAY HH 3 DOCUMENT 1253 06/02/54 AUTHOR! HAND EA ADDRESSEE: CONSUMERS POMER COPYEE: LETTER REPORT HOODRUFF JT 1 DOCUMENT 1254 06/15/54 AUTHOR! CONSUMERS POMER ADDRESSEE: DOM COPYEE: LETTER ONEIL RH ROWE VK 1 JU < 1 'vl 0 5 1 TITLE PAGE 180 REPORT OF CALL BY CLOFT, BOSTON OFFICE ON LUCAS TREE EXPERT COMPANY. RESULTS OF EXAMINATION OF JAMES R MAYFIELD'S DERMATITIS ALLEGEDLY CAUSED BY EXPOSURE TO 245T C T T L . COMMENTS AND SUGGESTIONS RELATIVE TO A DERMATITIS ALLEGEDLY CAUSED BY CONTACT WITH 245T CTTL. REQUEST FOR INFORMATION ON TREATMENT OF A SKIN INJURY ALLEGEDLY CAUSED BY 245T CTTL. REPORT OF A WORKER DEVELOPING A RASH AFTER USING ESTERON 245 DILUTED WITH FUEL OIL CTTL. USDI SUMMARY OF INFORMATION ON ESTERON 245 CTTL. USDI SMITH HL WILLIAMS GJ RICHARD OUILLET VS CONSUMERS POWER COMPANY. TRANSMITTAL OF A DERMATOLOGIST'S REPORT ON PATCH TESTS CONDUCTED ON A CONSUMERS POWER EMPLOYEE CTTL. STERLING JN NUMBER DOCUMENT 1255 AUTHOR) DOW ADDRESSEE: DON COPYEEi DATE 07/27/54 TYPE PAGES TELEX 1 STEWART LC GAY HH DOCUMENT 1256 AUTHOR: DOW ADDRESSEE-- DOW COPYEE: DOW 04/07/55 LETTER REPORT ROWE VK MUNSON NH GAY HH 3 DOCUMENT 1257 06/25/55 LETTER AUTHOR: DANIEL HARRELL CLINIC ADDRESSEE! DOW COPYEE: GOESL AG 1 DOCUMENT 1258 07/12/55 LETTER AUTHOR! ADDRESSEE! COPYEE: DOW DANIEL HARRELL DOW WILLIAMS GJ CLINIC ROWE VK GOESL AG CRANDALL RA 2 DOCUMENT 1259 AUTHOR: DOW ADDRESSEE: COPYEE: 08/00/50 REPORT 4 DOCUMENT 1260 00/00/53 NEWS 7 AUTHOR: DRILL VA ADDRESSEE: COPYEE: REPORT HIRATZKA T DOCUMENT 1261 AUTHOR: DOW ADDRESSEE: COPYEE: 00/00/50 REPORT 4 MCCOLLISTER DD TITLE PAGE 181 ESTERON 245 SKIN CONTACT APPEARS TO HAVE BURNED PERSON'S HANDS AND A RECOMMENDED TREATMENT IS REQUESTED C T T L . LUCAS TREE EXPERT COMPANY, ESTERON 245, PERLEY H CHASE. SMITH HL REQUEST FOR TOXICITY DATA ON ESTERON 245 FOLLOWING A REPORT OF A MILD CASE OF HEPATITIS CTTL. REPLY TO A LETTER REQUESTING TOXICITY DATA FOR ESTERON 245 IN CONNECTION WITH A MILD CASE OF HEPATITIS CTTL. GAY HH SMITH HL RESULTS OF TOXICOLOGICAL TESTS ON 245T. TOXICITY OF 24D AND 245T, A REPORT ON THEIR ACUTE AND CHRONIC TOXICITY IN DOGS (IND HYGIENE AND OCCUPATIONAL MEDICNE 7(61), 61-67). THE ACUTE ORAL TOXITY OF 245T TO RATS, MICE, GUINEA PIGS, AND CHICKS. ROWE VK SPENCER HC NUMBER DOCUMENT 1262 DATE 07/12/56 AUTHOR DOM ADDRESSEE< REESE R COPYEE: BOUNDY R DOCUMENT 1263 04/14/67 AUTHOR: DOM ADDRESSEE' COPYEE: DOCUMENT 1264 07/11/68 AUTHOR: DUNN CL ADDRESSEE: BAKER DM JR COPYEE: USDA DOCUMENT 1265 AUTHOR: USDA ADDRESSEE: COPYEE: 06/02/66 DOCUMENT 1266 AUTHOR: DOM ADDRESSEE: COPYEE: 04/21/65 DOCUMENT 1267 AUTHOR: DOM ADDRESSEE: DOM COPYEE: DOM 12/09/49 DOCUMENT 1268 AUTHOR: DOM ADDRESSEE: COPYEE: 10/26/54 TYPE LETTER PAGES 6 REPORT MOLF MA BRADLEY K REPORT 7 LETTER 2 NACA IND TASK FORCE FDA LEGIS 2 REPORT MHITE LC 5 LETTER ROME VK VEAZEY NR ALLEN MM REPORT 1 16* *0 -C CD TITLE PAGE 182 SKIN IRRITATION OF SOME IMPURITIES IN 243-TRICHLOROPHENOL AND TETRACHLOROBENZENE FROM VARIOUS SOURCES. INFORMATION ON THE TOXICOLOGY OF THE HERBICIDAL INGREDIENTS IN TORDON 144 (SUPPLEMENTAL SHEET REFERRING TO ITEMS ON PR FORM 9-228) CTTL . STATUS OF NACA TASK FORCE REPORT ON METABOLISM OF PHENOXY HERBICIDES CTTL. ON P HEM FISH AND WILDLIFE CAUTION STATEMENT (PGBEE 245T 464-272). SILVEX (DESCRIPTION OF TEST MATERIAL). REQUEST FOR AUTHORIZATION TO FINANCE ACUTE AND SUB ACUTE TOXICITY TESTS ON DOGS WITH 24D AND 245T. PUTNAM ME A COMPILATION OF INFORMATION ON THE TOXICOLOGY OF SILVEX (ACUTE AND SEMI CHRONIC TOXICITY OF SILVEX TO LABORATORY RATS). NUMBER DATE DOCUMENT 1269 05/19/65 AUTHORS ADDRESSEE: COPYEE: DOW I REA SKELLY NE TYPE PAGES REPORT 31 GILL HH LUECK AF DOCUMENT 1270 01/13/65 AUTHOR: DOW ADDRESSEE: CH BOEHRINGER SOHN COPYEE: DOW POFFENBERGER N LETTER FARNUM JH WGERM KUDSZUS GOERGENGO SAUERS RC 2 DOCUMENT 1271 04/09/65 LETTER AUTHOR: DOW TRAPP WB ADDRESSEES CH BOEHRINGER SOHN WGERM MERZ H COPYEE: DOW AMOS L A DOCUMENT 1272 04/22/65 LETTER AUTHOR: CH BOEHRINGER SOHN WGERM DOLL 0 ADDRESSEE: DOW COPYEE: 2 DOCUMENT 1273 01/28/65 LETTER AUTHOR: DOW TRAPP HB ADDRESSEE' CH BOEHRINGER SOHN WGERM MERZ H COPYEE: DOW DYLEWSKI SW 3 DOCUMENT 1274 AUTHOR: DOW ADDRESSEE' COPYEE: 12/03/64 DOCUMENT 1275 04/06/61 AUTHOR: BUCEK OC ADDRESSEE: COPYEE: DOW I APB I JWB <0 ^ I RMI LYNN GE s CO REPORT ABSTRACT DOW BARRONS I CMS I JWV I RPP ROWE VK KC 4 2 TITLE PAGE 183 245-TRICHL0R0PHEN0L PROCESS DATA AND PHYSICAL PROPERTIES SUMMARY (REPORT PE 65-22). HARRIS JS HUDBERG RN MILLER N SINKE GC ACKNOWLEDGES RECEIPT OF INFORMATION CTTL. TRAPP WB GRIESS GA SILVERSTEIN L LUECK AF TOXICOLOGICAL STUDIES, GAS CHROMATOGRAPHY AND INFRARED ANALYSES CTTL. GROTE 245T KONTRAKT. MERZ H SUMMARY OF TELEPHONE CONVERSATION HITH DR H MERZ, OF CH BOEHRINGER AND HB TRAPP, L SILVERSTEIN, H TOLKMITH, AND SW DYLEWSKI CTTL. GRIESS GA SILVERSTEIN L PROGIL PARIS, SUMMARY OF CHLORACNE EXPERIENCE. PROPYLENE GLYCOL, SILVEX, 24D OR 2A5T FOR FATTENING BEEF CATTLE (REPORT TA-176). BLAIR EH I JFK I KWM I TRN HAAGSMA TA I JS I PDL JOHNSON JE NUMBER DATE DOCUMENT 1276 07/01/60 AUTHOR: ADDRESSEE: COPYEE: DON DON I CED I JS I TRN WARREN LE DOCUMENT 1277 06/19/62 AUTHOR: DOW ADDRESSEE: COPYEE: DOW COLBY RW GREENE LM K I L I A N DJ NASH HA VANVALKENBURG W DOCUMENT 1278 AUTHOR: DOW ADDRESSEE COPYEE 07/29/59 DOCUMENT 1279 02/19/51 AUTHOR: DOW ADDRESSEE: COPYEE: DOW BRITTON JW HEATH SB NELSON WL DOCUMENT 1280 AUTHOR: DOW ADDRESSEE: COPYEE: 10/26/59 TYPE PAGES ABSTRACT 2 TRUCHELUT GB BARRONS KC I CMS I LJL JOHNSON JE WATSON AJ REPORT 2 MCCOLLISTER DD BARRONS KC DOSSER RC HART A LUCE EN PERKINS RP WRIGHT N REPORT 1 MCCOLLISTER DD REPORT 2 ROWE VK BERHENKE LF DAVIDSON JH HIRSCHKIND W RECHTIN HJ REPORT 1 MCCOLLISTER DD h GO ' 'J (-- 1 (T' Q TITLE PAGE 184 LARGE SCALE HYDROPHYTOTOXIN EXPERIMENTS IN LAKES AND STREAMS* 590000 (REPORT T A - 1 4 7 M 2 1 2872). BLAIR EH I CHH I OHH LYNN GE HOLZSCHU RG I JFK I RPP SCHAFFER AH RESULTS OF 90 DAY DIETARY FEEDING OF PROPYLENE GLYCOL ISOBUTYL ETHER ESTER OF SILVEX (DOHCO 171) TO RATS (K 44181-3). BOUNDY RH FALKENSTEIN JONES GD LYNN GE SHRADER SA HJ BROWN R GAY HH KAGY JF MCINTYRE HH TISDALE HL RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON BUTYL (AND ISOBUTYl) ALPHA-(245-TRICHL0R0PHEN0XY) PROPIONATE. ROGERS F RESULTS OF TOXICOLOGICAL TESTS ON ALPHA-245-TRICHL0R0PHEN0XY PROPIONIC ACID. BRANCH CB DUTTON HJ KELLY JA SOUTHHICK L BRITTON EC HAMMER OH LYNN GE SUNDERLAND HH RESULTS OF ACUTE AND SEMICHRONIC ORAL TOXICITY TESTS WITH RATS FED "SILVEX", OR 2(245-TRICHL0R0PHEN0XY) PROPIONIC ACID (K8690-1). ROHE VK NUMBER DOCUMENT 1281 DATE 12/04/68 AUTHOR! ADDRESSEE* COPYEE: MUTCHLER JE MUTCHLER JE KRMEL KL TREE RM TYPE PAGES CHART LETTER MINUTES 4 BAILEY CZ MORSE DB DOCUMENT 1282 00/00/69 AUTHOR: ADDRESSEE: COPYEE: FDA YANG GC REPORT HANSEN E 27 DOCUMENT 1283 AUTHOR: ADDRESSEE: COPYEE: 10/29/68 CHART REPORT 7 DOCUMENT 1284 05/04/66 AUTHOR: DOM ADDRESSEE: USDA ARS COPYEE: AUTH LEGIS HAMMER OH 3 DOCUMENT 1285 12/17/64 AUTHOR: CH BOEHRINGER SOHN ADDRESSEE! DOM COPYEE: LETTER 1 JAENICKE SILVERSTEIN L DOCUMENT 1286 12/15/64 AUTHOR: CH BOEHRINGER SOHN TRAPP MB ADDRESSEE: DOM COPYEE: LETTER DOM 2 L L th - DOCUMENT 1287 01/13/65 AUTHOR: DOM ADDRESSEE: CH BOEHRINGER SOHN COPYEE: DOM POFFENBERGER N LETTER FARNUM JH KUDSZUS GOERGEN GO SAUERS RC 00 2 TITLE PAGE 185 DOWICIDES PLANT ENVIRONMENTAL CONTROL TASK FORCE MINUTES 681115. DOW ROWE VK KRAMER CG STEHL RH THE PREPARATION AND CHARACTERIZATION OF CHLORINATED DIBENZO-P-DIOXINS. HEW POHLAND AE REQUEST FOR EXTENSION OF USES OF PHENOXY HERBICIDES IN PASTURE & RANGELAND (PP8F0669). M-3060 LIQUID HERBICIDE FORMULATION APPLICATION FOR TEMPORARY PERMIT TO SHIP AN ECONOMIC POISON FOR EXPERIMENTAL PURPOSES ONLY. ENCLOSURE LETTER FOR RABBIT TESTS CONDUCTED IN CONNECTION WITH 550000 PLANT DISINFECTION CTTL. MERZ R E P O R T ON C H L O R A C N E SEN T T O D O W CT.TL. KUDSZUS MERZ REQUEST FOR ADDITIONAL INFORMATION ON 2A5T PRODUCTION CTTL. TRAPP WB GRIESS GA SILVERSTEIN L LUECK AF NUMBER DATE DOCUMENT 1288 07/16/65 AUTHOR> GRUBAUGH K ADDRESSEE: COPYEE: DOM DOCUMENT 1289 AUTHOR: DOW ADDRESSEE! COPYEE! 00/00/68 DOCUMENT 1290 AUTHOR: DOW ADDRESSEE: COPYEE: 11/03/67 DOCUMENT 1291 07/29/63 AUTHOR: ADDRESSEE COPYEE-. DOW ROWE VK DOCUMENT 1292 00/00/63 AUTHOR: DAVIS JM ADDRESSEE: COPYEE: DOCUMENT 1293 00/00/63 AUTHOR: DAVIS JT ADDRESSEE COPYEE: DOCUMENT 129A 12/00/66 AUTHOR: DAVIS JT ADDRESSEE COPYEE: TYPE REPORT PAGES 9 MUTCHLER JE PRESENT 23 REPORT 5 REPORT I JLS WILTSE MG 13 LEGIS REPORT HUGHES JS A LEGIS REPORT HUGHES JS A LEGIS REPORT HUGHES JS 9 Heh-a 00 to TITLE PAGE 186 P R O C E S S S A M P L E S A N D AIR F I L T E R S A M P L E S FROM 2 6 5 B L D G 650716 TO 651117. SILVERSTEIN LG CHLORACNE DOW EXPERIENCE. TOXICITY IN SMALL ANIMALS (PA50.01.01.P1). TORDON A NEW HERBICIDE FOR VEGETATION CONTROL (DEFOLIATION CONFERENCE, US ARMY BIOLOGICAL LABORATORIES, FORT DETRICK, MD 630729 TO 630730). MONROE E MULLISON HR HOLF MA FURTHER OBSERVATIONS ON THE TOXICITY OF COMMERCIAL HERBICIDES TO B L U E G 1 L L S U N F I S H C P R O C E E D I N G S S W C C )( P P 0 F 0 8 6 3 ) ( P A 5 0 . 0 2 . 0 1 . P I ). LA WILD LIFE 8 FISHERIES VARIATIONS IN TOXICITY TO BLUEGILL SUNFISH OF PHENOXY HER B I CIDE S t H E E D S 11, 5 0 - 5 3 ) ( P P 0 F 0 8 6 3 ) ( P A 5 0 . 0 2 . 0 1 . P I ) . LA WILD LIFE 8 FISHERIES TOXICOLOGY OF PESTICIDES TO BLUEGILL SUNFISH TESTED DURING 1961 TO 1966( PP0F0863HPA50.02.01.P1). LA WILD LIFE AND FISHERI >'`277 NUMBER DOCUMENT 1295 DATE 03/00/67 AUTHOR: BOND CE ADDRESSEE: COPYEE: DOCUMENT 1296 AUTHOR DOW ADDRESSEE* COPYEE: 01/26/53 DOCUMENT 1297 01/19/68 AUTHOR: DOW ADDRESSEE) BAKER DM JR COPYEE: HAYS HW DOCUMENT 1298 05/02/61 AUTHOR: DOW ADDRESSEE KELSEY D COPYEE: DOW DOCUMENT 1299 02/11/69 AUTHOR RAY HC ADDRESSEE: COPYEE: DOCUMENT 1300 AUTHOR: ADDRESSEE: COPYEE: 01/10/69 DOCUMENT 1301 12/13/68 AUTHOR: HEW ADDRESSEE: DUNN CL COPYEE: USDA ARS DOCUMENT 1302 AUTHOR: DOW ADDRESSEE: COPYEE: * H-- 1 00 CO 07/00/68 TYPE PAGES LEGIS 16 REPORT MALICK J REPORT SMITH HL 11 CHART LETTER MCCOLLISTER FDA USDA 2 DD LETTER 1 MCINTYRE HH USDA SUNDERLAND WW PRESENT 12 USDI REPORT 8 LETTER 2 ROTHSCHILD A NACA IND TASK FORCE REPORT LENG ML 7 TITLE PAGE 187 PROGRESS REPORT OM AQUATIC WEED RESEARCHCPROJECT 773)DEPT OF F I S H E R I E S A N D W I L D L I F E ( P P 0 F 0 8 6 3 ) ( P A 5 0 . 0 2 . 0 1 . P I >. OR ST UNIV WILSON DC BRUSH AND WEED CONTROL ON RAILROAD RIGHTS OF WAY BY USE OF 24D AND 245T (PRESENTED BEFORE THE TORONTO RAILWAY CLUB TORONTO, CAN). PESTICIDE PETITION SF0675. HEW SEVERAL ITEMS ARE NOTED IN RESPONSE TO THE USDA'S LETTER OF 610A12 REGARDING KUROSAL SL C T T L . OUELLETTE FE REPORT OF THE NATL TECH ADVISORY COMM ON HATER QUALITY CRITERIA THE SAFE USE OF AQUATIC HERBICIDEStWSSA MEETING, LAS VEGAS, NV 690211 TO 690213). NORTHEASTERN HEED CONTROL CONF 690108 TO 690110. PP 8F0669 REQUESTING RESIDUE TOLERANCES FOR 245T CTTL. ON P REVIEW ON THE METABOLISM OF PHENOXY COMPOUNDS IN PLANTS AND ANIMALS (PP 8F0669). NUMBER DATE DOCUMENT 1303 03/16/67 AUTHOR: ALFORD HG ADDRESSEE DOM COPYEE: DOCUMENT 1309 AUTHOR: DOM ADDRESSEE: COPYEE: 00/00/69 DOCUMENT 1305 AUTHOR: NACA ADDRESSEE: COPYEE: 09/00/68 DOCUMENT 1306 06/15/65 AUTHOR: ADDRESSEE: COPYEE: DOM DOM COULTER KE HABERSTROH MH LUNDQUIST JT ROME VK TRAPP MB DOCUMENT 1307 AUTHOR: DOM ADDRESSEE: COPYEE: 07/30/65 DOCUMENT 1308 11/23/69 AUTHOR: DELISLE NG ADDRESSEE: COPYEE: DOCUMENT 1309 AUTHOR: DOM ADDRESSEE'- COPYEE: 11/00/69 TYPE PAGES LETTER USDA ARS SACHS SB 3 LEGIS. 1 REPORT 9 REPORT ERBEL AJ BOSSCHER H DIETZLER AJ HESS TM NORTON TR SAUERS RC MIDIGER AH 3 MEMO 3 CHART MEMO DOM MEMO 2 1 Q8>e -a OD TITLE REDDONIUSDA REO. 464-1801YOUR LETTER OF 0 9 2 3 PAGE 188 PORTION OF SENATE HEARING TRANSCRIPT CTTL. 240 2 45T SILVEX, MCPA RESIDUESiMETABOLISM IN A N I M A L S X P P 8F0676 REFILED AS PP 9F0761) CTTL. EFFECT OF 1245-TETRACHLOROBENZENE PURITY ON FORMATION OF CHL0RACNEGEN3 IN 245-TRICHL0R0PHEN0L PROCESS (SL 151874). BRADLEY KB GILL HH HOYLE H OLSON KJ SILVERSTEIN WOLF RR L CHAMBERLAIN LC GOERGEN GG KALLOS G POFFENBERGER N STAEHLING EC WRIGHT N BOEHRINGER REPORT, EXCERPTS. TCP, ACNE, T A S K F O R C E M E E T I N G 1. TCP CHLORACNE, ANILINE SECTION, PERSONNEL NUMBER DATE DOCUMENT 1310 07/20/53 AUTHOR CHOLAK J YEAGER D ADDRESSEE COPYEE: DOCUMENT 1311 12/00/69 AUTHOR BELL HM SMITH HN ADDRESSEE! COPYEE: DOCUMENT 1312 00/00/63 AUTHOR ARNOLD HR ADDRESSEE: COPYEE: DOCUMENT 1313 AUTHOR: DOH ADDRESSEE DOH COPYEE: 11/01/62 DOCUMENT 1319 08/01/52 AUTHOR DON ADDRESSEE DUXBURY MH COPYEE: GORDON HL DOCUMENT 1315 07/22/52 AUTHOR: DUXBURY MH ADDRESSEE: DOH COPYEE: DOCUMENT 1316 05/31/09 AUTHOR: CRUMMETT HB ADDRESSEE: COPYEE: TYPE PAGES REPORT 15 KEHOE RA TITLE PAGE 189 REPORT ON ENVIRONMENTAL SURVEY CARRIED OUT IN THE 295T PLANT OF MON AT NITRO, WV (PART 2). SCHAFER LJ UN1V OF CINCINNATI REPORT 95 PEDERSON RJ USDA GRASSLAND RESTORATION PART 2 BRUSH CONTROL (PA2.18.S3). POLK DB RECHENTHIN CA REPORT OK ST UNIV 37 THE EFFECTS OF 9-AMIN0-356-TRICL0R0PIC0LINIC ACID ON SEEDLING AND ESTABLISHED NATIVE GRASSES AND PERENNIAL FORBS (PA2.18.S3). LETTER 2 TOXICOLOGICAL INFORMATION ON A NUMBER OF AGRICULTURAL FORMULATIONS SUITABLE FOR SENDING TO RS DUNHAM OF THE USDA. HOL F MA RITTY PM LETTER 2 TOXICOLOGICAL DATA ON 295T IN RESPONSE TO A REQUEST FOR INFORMATION O N THE PHYSIOLOGICAL OR TOXIC EFFECTS OF ESTERON 295 CTTL. ROHE VK VET ADMIN HOSPITAL HA SMITH HL LETTER 1 REQUEST FOR INFORMATION ON PHYSIOLOGICAL AND TOXIC EFFECTS OF ESTERON 295 CTTL. VET ADMIN HOSPITAL HA REPORT DOH 11 FUNDAMENTAL PROBLEMS RELATED TO VALIDATION OF ANALYTICAL DATA ELABORATED ON THE EXAMPLE OF TCDD (TOX AND ENVIRON CHEM REVIEHS (3, 61-71). h"4 00 cn NUMBER DATE TYPE DOCUMENT 1317 00/00/62 REPORT AUTHOR: BUR OF SPORT FISHERIES & COPE OB ADDRESSEE COPYEE: PAGES 5 DOCUMENT 1318 00/00/63 AUTHOR: PALMER JS ADDRESSEE: COPYEE: REPORT RADELEFF RD 8 DOCUMENT 1319 AUTHOR: DOM ADDRESSEE: COPYEE: 00/00/50 REPORT 5 MCCOLLISTER DD DOCUMENT 1320 AUTHOR: DOM ADDRESSEE' COPYEE: 00/00/69 MEMO 2 DOCUMENT 1321 03/17/69 AUTHOR: FOOD CHEM NEMS ADDRESSEE: COPYEE: NEMS 5 DOCUMENT 1322 AUTHOR: ADDRESSEE' COPYEE: 00/00/68 REPORT 10 DOCUMENT 1323 08/29/68 AUTHOR: BALCOM RB CUMMINGS J ENIS HB TIMMONS FL ADDRESSEE! COPYEE: MINUTES BOYLE HD DEA S MCCLURE T AO -c# zh -( 00 CD TITLE PAGE 190 SPORT FISHERY INVESTIGATION (FISH S WILDLIFE SERVICE CIRCULAR 167, PAGES 26, 28, 29, 38 & 42). THE TOXICOLOGIC EFFECTS OF CERTAIN FUNGICIDES AND HERBICIDES ON SHEEP AND CATTLE (ANNALS NEW YORK ACADEMY OF SCIENCES, 729-736). US DA THE ACUTE ORAL TOXICITY OF 245T TO RATS, MICE, GUINEA PIGS AND CHICKS. ROWE VK SPENCER HC NOTES ON 245T REPORT BY BIONETICS CTTL. CARCINOGEN PAPER ON DDT, 245T WITHDRAWN FROM MEETING (FOOD CHEM NEWS, 17-21). DEMOBILIZATION PLANNING PART 1. BR-ARS RESEARCH ADVISORY COMMITTEE MEETING IRRIGATED AGRICULTURE RESEARCH 8 EXTENSION CENTER, PROSSER, H A . BRUNS VF COHAN H DEMINT RJ DEVANEY T MURRAY W OLIVER F NUMBER DOCUMENT 1324 DATE 03/19/59 AUTHOR i KLAUDER JV ADDRESSEE DOW COPYEEi DOW COULTER LL GREENE LM JONES GD LYNN GE TISDALE WL DOCUMENT 1325 11/05/53 AUTHOR: DOW ADDRESSEE COPYEE: DOW DUTTON WC LYNN GE SUNDERLAND NW DOCUMENT 1326 05/20/53 AUTHOR: DOW ADDRESSEE: DOW COPYEE: DOW SMITH HL DOCUMENT 1327 02/17/54 AUTHOR: COPPERS J ADDRESSEE: COPYEE: DOCUMENT 1328 AUTHOR: DOW ADDRESSEE: DOW COPYEE: 02/18/54 DOCUMENT 1329 AUTHOR: DOW ADDRESSEE DOW COPYEE: DOW 12/09/53 DOCUMENT 1330 AUTHOR: DOW ADDRESSEE: COPYEE: 00/00/53 TYPE PAGES CHART 4 LETTER ROWE VK BARRONS KC ELSHERE D HAMMER OH KAGY JF MCINTYRE HH WHITE LC REPORT 4 OYEN F ALLINSON RL GAY HH MACUTCHEON SM WRIGHT P LETTER HYMAS TA ROWE VK BRITTON JW SOUTHWICK L 2 REPORT DOW 1 REPORT OYEN F ROWE VK 1 LETTER HYMAS TA ROWE VK BARRONS KC REPORT WYSE H 1 9 G &eb- QO <1 TITLE PAGE 191 DISCUSSION AND RESULTS OF REPEATED INSULT METHOD OF PATCH TEST HITH KURON ON MALE SUBJECTS. BOUNDY RH GAY HH HART A KILIAN DJ PERKINS RP WRIGHT N COLBY RW GRAY HE HYMAS TA LUCE EN STENGER VA RESULTS OF SKIN, EYE, AND ACUTE ORAL TOXICITY TESTS ON ESTERON BRUSH ILLER. KILLER. BOUNDY RH JONSON JE MARTIN D DAVIDSON JH KAGY JF MELASS VH ACUTE ORAL TOXICITY OF DOW ESTERON BRUSH KILLER FOR CATTLE. IRISH DD VANHORN JG JOHNSON JE ESTERON BRUSH KILLER (TISSUE EXAMINATION). HISTOPATHOLOGIC IMPRESSIONS OF STEER FED DOW ESTERON BRUSH KILLER. ESTERON BRUSH KILLER TOXICITY TO CATTLE. JOHNSON JE LYNN GE BRUSH KILLER T (SKIN IRRITATION). NUMBER DOCUMENT 1331 AUTHOR! DOM ADDRESSEE* COPYEE: DATE 00/00/53 DOCUMENT 1332 AUTHOR: DOM ADDRESSEE COPYEE: 00/00/53 DOCUMENT 1333 04/12/68 AUTHOR: MI ST UNIV ADDRESSEE: COPYEE: DOCUMENT 1334 04/06/68 AUTHOR: DARROH RA ADDRESSEE COPYEE: DOCUMENT 1335 04/03/68 AUTHOR: DARROH RA ADDRESSEE: COPYEE: DOCUMENT 1336 00/00/61 AUTHOR: DOM ADDRESSEE COPYEE: DOCUMENT 1337 AUTHOR: DOM ADDRESSEE: DOM COPYEE: 10/12/66 DOCUMENT 1338 AUTHOR: DOM ADDRESSEE: COPYEE: 10/24/66 TYPE REPORT HYSE H PAGES 3 REPORT MOLF MA 8 REPORT 25 TSCHIRLEY FH REPORT 12 MINARIK CE REPORT MINARIK CE 5 NEHS REPORT LOCKMOOD DT 5 REPORT 1 SILVERSTEIN LG CHASE F REPORT 1 SILVERSTEIN LG h-* 00 00 TITLE BRUSH KILLER T (EYE IRRITATION). PAGE 192 DOW BRUSH KILLER T CACUTE ORAL TOXICITY). WYSE H AN ASSESSMENT OF ECOLOGICAL CONSEQUENCES OF THE DEFOLIATION PROGRAM IN VIETNAM. PERSISTENCE OF HERBICIDES IN SOIL AND HATER (APPENDIX D). US ARMY TOXICITY OF HERBICIDES IN USE IN RVN (APPENDIX C). US ARMY TOXICOLOGIC INFORMATION ON 245-TRICHL0R0PHEN0L (TOX AND APPLIED PHARMACOLOGY 3, 63-70). MCCOLLISTER DD ROWE VK BUTYL ESTER OF 245T, 489 BLDG, DIRECT ESTER PROCESS (REQUEST FOR SCREENING OR APPLICATION TESTING). DIRECT ESTER PLANT 489 BLDG, PROCESS SAMPLES (REQUEST FOR SCREENING OR APPLICATION TESTING). NUMBER DOCUMENT 1339 AUTHOR DOW ADDRESSEE DOW COPYEE: DATE 07/17/67 TYPE REPORT HOYLE HOYLE PAGES 1 DOCUMENT 1340 08/00/68 REPORT 152 AUTHOR BIONETICS RES LAB MD ADDRESSEE COPYEE NATL CANCER INST MD DOCUMENT 1341 AUTHOR DOW ADDRESSEE COPYEE: 02/22/67 REPORT OHARE CP 3 DOCUMENT 1342 AUTHOR: DOW ADDRESSEE COPYEE: 01/25/67 CHART 2 REPORT HURDELBRINK MJ DOCUMENT 1343 AUTHOR: DOW ADDRESSEE: COPYEE: 00/00/65 REPORT PERRY KW 3 DOCUMENT 1344 AUTHOR DOW ADDRESSEE COPYEE: 10/16/64 REPORT SKELLY NE 1 DOCUMENT 1345 AUTHOR: DOW ADDRESSEE: COPYEE: 02/00/65 REPORT OHARE C 16 DOCUMENT 1346 AUTHOR DOW ADDRESSEE: COPYEE: $-> )fe eft H-* 00 CO 02/00/65 REPORT OHARE CP 6 TITLE PAGE 193 2A5T SAMPLES FROM MONSANTO & DIAMOND (REQUEST FOR SCREENING OR APPLICATION TESTING). FERNANDEZ JB EVALUATION OF CARCINOGENIC, TERATOGENIC, AND MUTAGENIC ACTIVITIES OF SELECTED PESTICIDES AND INDUSTRIAL CHEMICALS, VOLUME TWO TERATOGENIC STUDY IN MICE AND RATS (PB-223 160). BONE MARRON SUMMARY (TCDD). SADEK SE HEMATOLOGY SUMMARY (TCDD). SADEK S TCDD (USE TOX. SPL. 127). "TETRACHLORODIBENZO-P-DIOXANS" ISOLATED FROM OIL #658 (REQUEST FOR SCREENING OR APPLICATION TESTING). THE EFFECTS OF REPEATED APPLICATIONS OF SYMMETRICAL TETRACHLORODIBENZODIOXIN ON GUINEA PIG EARS (FILE T36.25-66681-5). OLSEN K ROHE VK THE EFFECTS OF REPEATED APPLICATIONS OF SYMMETRICAL TETRACHLORODIBENZODIOXIN ON THE RAT EAR (FILE T36.25-66681-3). OLSEN K ROHE VK NUMBER DOCUMENT 1347 DATE 03/00/65 TYPE REPORT PAGES 15 AUTHOR DOW ADDRESSEE COPYEE OHARE CP DOCUMENT 1348 AUTHOR DOW ADDRESSEE DOW COPYEE 05/12/58 MEMO WOLF MA HYMAS T 3 DOCUMENT 1349 AUTHOR: DOW ADDRESSEE- COPYEE: 00/00/57 REPORT 1 DOCUMENT 1350 01/24/67 REPORT 17 AUTHOR: ADDRESSEE COPYEE: DEPT OF THE DOW I DDM I ESS I HWL I JT I MAW I RGH I TTT I WRN INTERIOR GA NICHOLSON 1HP I CLM I EEA I FJL I JFK I JWL I MGW I RLG I TWH DOCUMENT 1351 AUTHOR: DOW ADDRESSEE: DOW COPYEE: 12/28/61 LETTER 2 WINSTON AW JR RITTY PM DOCUMENT 1352 AUTHOR: DOW ADDRESSEE: DOW COPYEE: 02/18/58 LETTER 2 WINSTON AW JR JOSEPHS MJ CO o TITLE PAGE 194 THE FORMATION OF FOLLICULITIS IN THE RABBIT EAR FOLLOWING A SINGLE SUBCUTANEOUS INJECTION OF SYMMETRICAL TETRACHLORODIBENZODIOXIN IN BENZENE (ILE T36.25-66681-4). OLSEN K ROME VK TOXICITY INFORMATION ON SOME RECENTLY RELEASED DOW AGRICULTURAL CHEMICALS. (TEXAN REPORT 700900 TO 701100). THE SOUTHEAST MATER LAB AND ITS PROGRAM (20TH ANNUAL MEETING OF SOUTHERN MEED CONFERENCE 670124 TO 670126 LA). I CLS I EHB I HA I JLS I JMV I POL I TAH I VKR I CTL I ERL I HJ I JRF I KCB I RCH I TJP I WPF FISH TOXICITY OF SOME HERBICIDE FORMULATIONS AND THEIR INGREDIENTS. FISH TASTE THRESHOLD AND TOXICITY OF SOME AQUATIC HERBICIDE MATERIALS. NUMBER DOCUMENT 1353 DATE 10/16/50 AUTHOR! DOW ADDRESSEE: DOW COPYEEi DOCUMENT 1354 AUTHOR! DOW ADDRESSEE! DOW COPYEE: DOW 11/21/60 DOCUMENT 1355 00/00/66 AUTHOR: DAVIS JT ADDRESSEE: COPYEE: DOCUMENT 1356 04/00/69 AUTHOR! NORTH TX ST UNIV ADDRESSEE! COPYEE: DOCUMENT 1357 04/00/69 AUTHOR! ALABASTER JS ADDRESSEE: COPYEE: DOCUMENT 1358 AUTHOR: DOW ADDRESSEE: COPYEE: 01/00/54 DOCUMENT 1359 AUTHOR: ADDRESSEE: COPYEE-* 11/00/66 TYPE PAGES LETTER 4 REPORT POWERS TJ ROWE VK LETTER RAYNOR RN WARREN LE COULTER LL REPORT HUGHES JS 2 9 TITLE PAGE ODOR AND TASTE THRESHOLDS AND FISH TOXICITY OF SME ORGANIC COMPOUNDS CTTL. 195 LD50 ON FISH OF VARIOUS HERBICIDES CTTL. RITTY PM SWEZEY AH TOXICITY OF PESTICIDES TO BLUEGILL SUNFISH TESTED DURING 610000 TO 660000. LA WILDLIFE AND FISHERIE NEWS 9 EFFECTS OF FIVE HERBICIDES ON THREE GREEN ALGAE CTX JOUR OF SCIENCE XX(4)* 329-337). REPORT SMITH DL VANCE BD NEWS 7 SURVIVAL OF FISH IN 164 HERBICIDES, INSECTICIDES, FUNGICIDES, WETTING AGENTS AND MISCELLANEOUS SUBSTANCES (INTERNATIONAL PEST CONTROL, 29-35). REPORT MINISTRY OF AG 1FISHERIES REPORT 10 SILVEX (SILVEX TECHNICAL BULLETIN 1). REPORT 4 SUMMARY OF THE BIONETICS TERATOLOGY STUDY ON 24D AND RELATED COMPOUNDS. Uz*b-(T, H*4 CO H-4 NUMBER DOCUMENT 1360 DATE 00/00/69 AUTHOR HEGYI E ADDRESSEE COPYEE DOCUMENT 1361 10/00/63 AUTHOR BASF WGERM ADDRESSEE COPYEE DOCUMENT 1362 04/22/63 AUTHOR DOM ADDRESSEE DELMOR FJ COPYEE DOM USDA ARS DOCUMENT 1363 AUTHOR DOM ADDRESSEE COPYEE 00/00/66 DOCUMENT 1364 AUTHOR DOM ADDRESSEE DOM COPYEE 06/00/65 DOCUMENT 1365 00/00/57 AUTHOR FISHER P ADDRESSEE COPYEE DOCUMENT 1366 AUTHOR DOM ADDRESSEE COPYEE 08/30/50 TYPE PAGES NEMS 12 REPORT LUPTAKOVA A NEMS REPORT OETTEL H 16 LETTER LYNN GE DOD ROME VK REPORT 2 39 REPORT 21 MUTSCHLER JE REPORT 5 HAMBURG EPPENDORF ABSTRACT ROME VK 1 ^4 CO ro TITLE PAGE THE PART OF ALKALI IN THE KERATOOENOUS EFFECT OF TECHNICAL 245-TRICHL0R0PHEN0L CBERUFS-DERMATOSEN 6. 327-337HGERMAN) . STOTA Z 196 NEUERE ERKENNTNISSE UBER 0ESUNDHEITS6EFAHRLICHE QRBEITSSTOFF (MODERNE UNFALLVERHTUNG 8, 3-16MGERMAN). INFORMATION ON TOXICITY OF 240 AND 245T, LACK OF ILL EFFECTS ON DOM WORKERS INVOLVED IN MANUFACTURING 24D AND 245T AND LACK OF COMPLAINTS FROM USERS OF 24D AND 245T CTTL. SHAM HG SUNDERLAND MM 199 BUILDING MIPE SAMPLES. 199 BLDG AIR SAMPLES. OCCUPATIONAL ACNE (SOCALLED CHLORACNE) DUE TO CHLORINATED AROMATIC , CYCLIC ETHER (DERMATOLOGICA 115, 540). UNIV S K1MMIG K SCHULZ KH INTERIM REPORT ON THE ACUTE AND SUBACUTE ORAL TOXICITY OF 245T FOR DOGS (ACETIC ACID (245-TRICHL0R0PHEN0XY) TOXICITY). NUMBER DOCUMENT 1367 AUTHOR: DOW ADDRESSEE COPYEE: DATE 12/31/69 DOCUMENT 1368 00/00/57 AUTHOR: KIMMIG J ADDRESSEE: COPYEE: DOCUMENT 1369 06/00/63 TYPE PAGES ABSTRACT 1 EMERSON JL REPORT SCHULZ KH 5 REPORT 12 AUTHOR: BUTLER PA ADDRESSEE: COPYEE: DOCUMENT 1370 08/00/6A USDI REPORT 5 AUTHOR BUTLER PA ADDRESSEE: COPYEE: DOCUMENT 1371 00/00/53 USDI REPORT 7 AUTHOR: DRILL VA ADDRESSEE COPYEE: HIRATZKA T L>zeb C> CO TITLE PAGE 197 ORAL MEDIAN LETHAL DOSE (LD 50) DETERMINATION ON 245T IN THE FEMALE RAT. CERBIO CG THOMPSON DJ OCCUPATIONAL CHLORACNE CAUSED BY AROMATIC CYCLIC ETHERS (DERMATOLOGICA 115, 540-5A6)(LECTURE DELIVERED AT THE 23RD CONGRESS OF GERMAN DERMATOLOGISTS, VIENNA, 560523 TO 560527). UNIV OF HAMBURG EPPENDOR COMMERCIAL FISHERIES INVESTIGATIONS (PESTICIDE WILDLIFE STUDIES, A REVIEW OF FISH AND WILDLIFE SERVICE INVESTIGATIONS, CIRCULAR 167HPETITION FOR THE ESTABLISHMENT OF TOLERANCES FOR THE PESTICIDE CHEMICAL, 245T ON RAW AGRICULTURAL COMMODITIES, SECTION C, FULL REPORTS OF INVESTIGATIONS MADE WITH RESPECT TO THE SAFETY OF THE PESTICIDE CHEMICAL, 245T). COMMERCIAL FISHERY INVESTIGATIONS (PESTICIDE WILDLIFE STUDIES 630000, A REVIEW OF FISH AND WILDLIFE SERVICE INVESTIGATIONS DURING THE CALENDAR YEAR, CIRCULAR 199)(PETITION FOR THE ESTABLISHMENT OF TOLERANCES FOR THE PESTICIDE CHEMICAL, 245T ON RAW AGRICULTURAL COMMODITIES, SECTION C, FULL REPORTS OF INVESTIGATIONS MADE WITH RESPECT TO THE SAFETY OF THE PESTICIDE CHEMICAL, 245T). TOXICITY OF 24D AND 245T, A REPORT ON THEIR ACUTE AND CHRONIC TOXICITY IN DOGS (IND HYGIENE AND OCCUPATIONAL MEDICINE 7, 61-67HPETITION FOR THE ESTABLISHMENT OF TOLERANCES FOR THE PESTICIDE CHEMICAL, 245T ON RAW AGRICULTURAL COMMODITIES, SECTION C, FULL REPORTS OF INVESTIGATIONS MADE WITH RESPECT TO THE SAFETY OF THE PESTICIDE CHEMICAL, 245T). WAYNE UNIV NUMBER DOCUMENT 1372 DATE 00/00/50 TYPE REPORT PAGES A AUTHOR I DOH ADDRESSEE! COPYEE: DOCUMENT 1373 MCCOLLISTER DD 12/08/67 REPORT 1A AUTHOR DOM ADDRESSEE: COPYEE: DOCUMENT 137A 05/09/62 AUTHOR BAUER H ADDRESSEE! COPYEE! DOM DOCUMENT 1375 00/00/62 REPORT BERGMAN ROHE VK REPORT 19 7 AUTHOR! JONES EL ADDRESSEE! COPYEE: DOCUMENT 1376 AUTHOR: ADDRESSEE: COPYEE: 00/00/57 DOCUMENT 1377 AUTHOR: ADDRESSEE: COPYEE: 00/00/68 DOCUMENT 1378 05/0A/67 AUTHOR: BLUMS ZB ADDRESSEE: COPYEE: j~IA CD KRIZEK H MEMO MEMO REPORT LONDONO F A 1 10 TITLE PAGE 198 THE ACUTE ORAL TOXICITY OF 245T TO RATS MICE, GUINEA PIGS AND CHICKS (PETITION FOR THE ESTABLISHMENT OF TOLERANCES FOR THE PESTICIDE CHEMICAL, 245T ON RAM AGRICULTURAL COMMODITIES, SECTION C, FULL REPORTS OF INVESTIGATIONS MADE WITH RESPECT TO THE SAFETY OF THE PESTICIDE CHEMICAL, 2<*5T). ROME VK SPENCER HC PETITION FOR THE ESTABLISHMENT OF TOLERANCES FOR THE PESTICIDE CHEMICAL, 2<*5T ON RAM AGRICULTURAL COMMODITIES, SECTION C, FULL REPORTS OF INVESTIGATIONS MADE MITH RESPECT TO THE SAFETY OF THE PESTICIDE CHEMICAL 245T. INDUSTRIAL POISONING IN THE MANUFACTURE OF CHLOROPHENOL COMPOUNDS (ARCHIV FR GEHERBEPATHOLOGIE UND GEHERBEHYGIENE 18, 538-555 610000). SCHULZ KH SPIEGEL BERG U A TECHNIC FOR TESTING ACNEGENIC POTENCY IN RABBITS, APPLIED TO THE POTENT ACNEGEN TCDD(JOUR OF INVESTIGATIVE DERMATOLOGY 39, 511-517)(PRESENTED AT THE TMENTY-THIRD ANNUAL MEETING OF THE SOCIETY FOR INVESTIGATIVE DERMATOLOGY INC CHICAGO IL 620626). UNIV OF CHICAGO ROUGH DRAFT REPORT ON CHLORACNE CTTL. BIBLIOGRAPHY CTTL. CLINICAL STUDIES, OCCUPATIONAL ACNE (FABIO LONDONO, MEDICINA CUTANEA 3, 225-232 660000). NUMBER DOCUMENT 1379 AUTHORi ADDRESSEE! COPYEE: DATE 00/00/55 TYPE NEWS REPORT PAGES 22 DOCUMENT 1380 AUTHOR! DOW ADDRESSEE' COPYEEi 02/00/66 CHART REPORT 2 DOCUMENT 1381 AUTHOR! DOW ADDRESSEE COPYEE: DOW 07/16/65 REPORT GILL HH MUTCHLER JE 1 DOCUMENT 1382 05/05/66 AUTHOR HOYLE HR ADDRESSEE COPYEE: DOW LUECK AF REPORT 13 SILVERSTEIN LG DUNKEL BARGER DC WALKER RE DOCUMENT 1383 03/20/68 AUTHOR! DOW ADDRESSEE COPYEE: DOW HUTCHENREUTHER CO RAGER EE REPORT 9 HOYLE HR DUNKEL BARGER DC KREGER WP ROSE R DOCUMENT 1384 AUTHOR: DOW ADDRESSEE COPYEE: 00/00/65 CHART 3 DOCUMENT 1385 AUTHOR: DOW ADDRESSEE COPYEE: 00/00/65 CHART 3 Ib'tb-CL DOCUMENT 1386 AUTHOR: DOW ADDRESSEE: COPYEE: 00/00/65 CHART 3 h-4 CO en TITLE PAGE EXCERPTS FROM ARTICLE, REFERENCES TO PAGES OF ORIGINAL. 199 265 BLDG SPL PT, CATCHALL STORAGE PROCESS SAMPLES. PROCESS SAMPLES FROM 265 BLDG DATED 650708 SAMPLE RECORD AL H9-127. SILVERSTEIN LG 199 BUILDING WIPE SAMPLES FOR CHLORACNE CONTAMINATION 660000 TO DATE (T17.9-12-3). GOERGEN GG WILSON AW GORDON HL WIPE TESTS IN 199 BUILDING DURING TRICHLOROPHENOL PROCESS DISMANTLING (T17.9-12-3). SILVERSTEIN LG HERITIER WJ LOHRKE EE STAEHLING EC HOLDER BB MORSE D 703 BLDG WIPE SAMPLES. WIPE SAMPLESI979 BLDG). 338 BLDG PROCESS SAMPLES N UU MM BB EE RR DOCUMENT 1387 AUTHOR: DOW ADDRESSEE COPYEE: DOCUMENT 1388 AUTHOR: DOW ADDRESSEE COPYEE: DOCUMENT 1389 AUTHOR: DOW ADDRESSEE: COPYEE: DOCUMENT 1390 AUTHOR: DOW ADDRESSEE: COPYEE: DOCUMENT 1391 AUTHOR: DOW ADDRESSEE: COPYEE: DOCUMENT 1392 AUTHOR: DOW ADDRESSEE: COPYEE: DOCUMENT 1393 AUTHOR: DOW ADDRESSEE: COPYEE: DOCUMENT 1394 AUTHOR: DOW ADDRESSEE DOW COPYEE: DATE 00/00/65 TT YY PP EE CHART P A G E SS 6 00/00/65 CHART 3 00/00/65 CHART 3 00/00/65 CHART 12 00/00/65 CHART 3 03/16/65 AUTH 1 SILVERSTEIN LG 05/14/65 CHART 5 00/00/65 REPORT MUTCHLER JE 9 ebth-Q, CO oe TITLE 267 BLDG WIPE SAMPLES. PAGE 200 NA SALT FILTER PRESS CAKEC267 BUILDING) 267 BUILDING!ISOOCTYL ESTER PRODUCT). 267 BUILDINGC2A5T ACID PRODUCT). 267 BUILDINGCAIR SAMPLES). SPIKED SAMPLES OF SILVEX, RONNEL, 2A5T BUTYLESTER (REQUEST FOR SCREENING OR APPLICATION TESTING). 2A5T PROCESS SAMPLEStAGLUKON GESELLSCNAFT). PROCESS SAMPLES FROM 265 BLDG DATED 650708 (AL-H9-127). SILVERSTEIN LG NUMBER DOCUMENT 1395 DATE 00/ 00/68 AUTHOR ADDRESSEE COPYEE CAMPBELL HUANG A AD TYPE NEWS REPORT FDA RESS J PAGES 2 DOCUMENT 1396 03/00/69 AUTHOR HANSEN E " FDA ADDRESSEE COPYEE DOCUMENT 1397 02/19/68 AUTHOR ADDRESSEE COPYEE DON DON LYNN NOLF GE MA REPORT HEN 28 REPORT 8 DUDDLES GA ALEXANDER HC SHANNON ES DOCUMENT 1398 AUTHOR: DON ADDRESSEE: COPYEE: 01/07/60 REPORT 6 DOCUMENT 1399 10/30/53 AUTHOR: DREYER F ADDRESSEE: COPYEE: ADAMS EM BARRONS KC DAVIDSON JH GREENE LM MACCUTCHEON WRIGHT P REPORT 7 ALLEN NN BESHGETOOR AN DON KAGY JF PRESCOTT RF DOCUMENT 1900 10/22/56 AUTHOR: DEPT OF HEALTH VA ADDRESSEE: DOW COPYEE LETTER KAYE S 1 TITLE PAGE 201 CHEMICAL AND TOXICOLOGICAL EVALUATIONS OF ISOLATED AND SYNTHETIC CHLORO DERIVATIVES OF DIBENZO-P-DIOXIN. FIRESTONE D VERRETT J HIGGINBOTHAM GR THE PREPARATION AND CHARACTERIZATION OF CHLORINATED DIBENZO-P-DIOXINS. POHLAND AE YANG GC THE ACUTE FISH TOXICITY OF TORDON FORMULATIONS 144, 155, 202, 212 AND 225. BARRONS KC TEAL JL KENAGA EE WILTSE MO A RESIDUE STUDY OF SILVEX IN FISH LIVING IN KURON CONTAINING HATER. RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON DOH BRUSH KILLER T. ALLINSON RL BOUNDY RH DUTTON HC LUCE EN SUNDERLAND HH ALQUIST FN BRITTON EC GAY HH LYNN GE WHITE L REQUEST FOR INFORMATION CONCERNING POSSIBLE EXPOSURE TO ESTERON 245 AND MORTALITY IN CHILDREN CTTL. ht> v b -< , NUMBER DOCUMENT 1401 AUTHOR) DOM ADDRESSEE DOM COPYEE: DATE 10/26/56 DOCUMENT 1402 AUTHOR: DOM ADDRESSEE COPYEE: 06/21/67 DOCUMENT 1403 04/06/65 AUTHOR) BLEIBERG J ADDRESSEE) DOM COPYEE) DOCUMENT 1404 07/27/56 AUTHOR) DOM ADDRESSEE MILLER MC COPYEE: DOM DOCUMENT 1405 01/04/56 AUTHOR: SHANKS RM ADDRESSEE: COPYEE: DOCUMENT 1406 12/16/55 AUTHOR: CHINBURG H ADDRESSEE: DOM COPYEE: DOCUMENT 1407 AUTHOR) DOM ADDRESSEE) DOM COPYEE: 12/28/55 DOCUMENT 1408 06/17/55 AUTHOR) DOM ADDRESSEE) BIERER BH COPYEE) DOW HYMAS TA h=* CD CO TYPE LETTER ROME VK GAY HH PAGES 2 REPORT GORDON HL 1 LETTER BRODKIN RH HOLDER BB 2 LETTER ROHE VK GAY HH LETTER MEMO 2 2 LETTER DOM GAY HH 1 LETTER GAY HH CHINBURG H 1 LETTER ROME VK ROME VK SMITH HL 1 TITLE PAGE 202 ESTERON 245 INQUIRY OF DR. SIDNEY KAYE OF THE COMMONWEALTH OF VA, DEPT OF HEALTH. ESTERON 245IREP0RT OF TELEPHONE INQUIRIES). TCDD IS PROBABLE CAUSE BEHIND THE CHLORACNE FOUND IN HORKERS AT PLANT MAKING 24D AND 245T CTTL. TOXICOLOGICAL INFORMATION ON ESTERON 99 CTTL. BESSIE SPERRY. CONSUMER LETTER. LETTER DISCOUNTING 24D AND 245T AS THE CAUSE OF HEPATITIS CTTL. 24D AND ALLEGED TURKEY ILLNESS CTTL. BARRONS KC WILLIAMS GJ GORDON HL NUMBER DATE TYPE PAGES DOCUMENT 1409 03^03/53 LETTER 3 AUTHOR: ADDRESSEE: COPYEE: REPORT DON ROWE VK BOURBON COUNTY HOSPITAL KINNARD DOW GAY HH BW TITLE PAGE 203 I N F O R M A T I O N R E G A R D I N G I N J U R I E S W H I C H M I G H T BE C A U S E D TO P E R S O N S HANDLING 24D AND 245T CTTL. DOCUMENT 1410 07/17/51 AUTHOR: DOW ADDRESSEE REAGEL FV COPYEE: DOW SMITH HL LETTER 2 ROWE VK ST HIGHWAY DEPT MO BRANCH CB WILLIAMS GJ SKIN TOXICITY INFORMATION ON 24D, 245T AND SODIUM TCA IN RESPONSE TO REQUEST CTTL. C OULTER LL GAY HH DOCUMENT 1411 07/23/67 LETTER AUTHOR: DOW ROWE VK A DDRESSEE: IL DEPT OF P U B L I C H E A L T H R O S E NJ COPYEE: DOW KRAMER CJ ENCLOSED DATA ON TOXICITY OF 24D AND 245T PRODUCTS CTTL. DOCUMENT 1412 05/09/66 AUTHOR: DOW ADDRESSEE' PRESCOTT C COPYEE: LETTER 2 TOXICOLOGICAL DATA ON 245T ESTERON PRODUCTS CTTL. WOLF MA VT ELECTRIC COOPERATIVE DOCUMENT 1413 AUTHOR: DOW ADDRESSEE:: DOW COPYEE: DOW 09/13/62 LETTER WOLF MA HOLDEMAN WOLF MA TOXICOLOGICAL INFORMATION ON A NUMBER OF HERBICIDE FORMULATIONS FOR TRANSMITTAL TO TURKISH AUTHORITIES. DOCUMENT 1414 10/06/61 LETTER 2 CLAIM 1556026. AUTHOR: DOW ROWE VK ADDRESSEE: HARWARE MUTUALS SENTRY L WANEK WE COPYEE: DOW ROWE VK SINCLAIR R DOCUMENT 1415 02/13/56 AUTHOR: DOW ADDRESSEE:: DOW COPYEE: DOW DOCUMENT 1416 01/26/56 ^ AUTHOR' C O U L T E R LL ADDRESSEE : DOW COPYC^ FLETCHER FW ^ iA LETTER ROWE VK C O U L T E R LL FLETCHER FW LETTER DOW ROWE VK 2 RECOMMENDATION NOT TO USE BACKPACK SPRAYING WHEN APPLYING ESTERON BRUSH KILLER AND ESTERON 245 AS INHALATION OF THE MIST MAY CAUSE RESPIRATORY PROBLEMS CTTL. PAPERS PRESENTED AT THE CHARTER MEETING OF THE WSA, NEW YORK CITY, 560104 AND 560105. -HA NUMBER DATE DOCUMENT 1417 07/06/55 AUTHOR: SINGER RH ADDRESSEE: DOM COPYEE: TYPE PAGES LETTER UNIV OF KY ROWE VK 2 TITLE 24D NEEDED FOR ANALYSIS C T T L . PAGE 204 DOCUMENT 1418 11/20/53 LETTER 2 LETTER REQUESTING INFORMATION ON ESTERON AND COMMENTS ON HERBICIDE CLAIM CTTL. AUTHOR: CAN NATL RAILWAYS M U NR O DJ ADDRESSEE-' DON ROWE VK COPYEE: DOCUMENT 1419 09/01/53 AUTHOR: DON ADDRESSEE: CALLOWAY JB COPYEE: DON LETTER WILLIAMS GJ FARMERS RURAL RONE VK 1 LETTER INDICATE CONCENTRATION OF TWO PARTS FOUR PARTS PER MILLION IS FATAL CTTL. ELECTRIC C SMITH HL PER MILLION IS SAFE AND DOCUMENT 1420 AUTHOR: DON ADDRESSEE: DON COPYEE: 12/23/59 LETTER RONE VK C O U L TE R LL 2 SILVEX. DOCUMENT 1421 AUTHOR: DON ADDRESSEE: COPYEE: 08/00/50 REPORT 4 RESULTS OF TOXICOLOGICAL TESTS ON 245T. DOCUMENT 1422 06/16/64 AUTHOR: ADDRESSEE: COPYEE: DON DON EPSTEIN J HAKE CL JONES GD LYNN GE PAVKA RC REPORT 1 OLSON K BARRONS KC FALKENSTEIN WJ HART A KAGY JF MCINTYRE HH SHRADER SA RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON 245TCCURRENT DOW PRODUCT). OYEN F BOUNDY RH G O R D O N HL HOL DEMAN GE K IL I A N DJ MULL ISON NR WILSON AN ELSHERE D GREENE LM JOHNSTON RV LUCE EN NORTON TR WRIGHT N DOCUMENT 1423 03/22/61 AUTHOR: ADDRESSEE: COPYEE: DON DON DON MCINTYRE HH LETTER RITTY PM LYNN GE COULTER LL 2 COVER LETTER FOR DATA SUPPORTIVE OF HERBICIDAL PROPRTIES OF KUROSAL SL A ND KUROSAL G CTTL. FALSEY WP JOHNSON JE NUMBER DOCUMENT 1424 AUTHOR: ADDRESSEE: COPYEE: DATE 00/00/69 DOCUMENT 1425 AUTHOR: DOM ADDRESSEE: COPYEE: 10/02/50 DOCUMENT 1426 00/00/57 AUTHOR: CHENOWETH MB ADDRESSEE COPYEE: DOCUMENT 1427 AUTHOR: DOM ADDRESSEE: DOM COPYEE: 00/00/64 DOCUMENT 1428 08/17/64 AUTHOR: HOWLAND ML ADDRESSEE: DOM COPYEE DOCUMENT 1429 08/05/52 AUTHOR: DOM ADDRESSEE DUXBURY MH COPYEE: DOM DOCUMENT 1430 04/20/61 AUTHOR: DOM ADDRESSEE: IUKA CLINIC COPYEE: DOCUMENT 1431 03/04/65 AUTHOR: MICKLESON KNP ADDRESSEE: DOM COPYEE: -O ro o ~A TYPE REPORT PAGES 18 ABSTRACT POWERS TJ 1 NEWS REPORT 8 PRESENT I JBC I DBJ LETTER 14 1 LETTER G O R D O N HL VA HOSPITAL ROWE VK 1 LETTER GAY HH SEGARS KS 1 LETTER 1 PALMERSTON NORTH TITLE PAGE 205 NOTES FOR THE PREPARATION OF A LETTER OF INTEREST RELATED TO AIR FORCE BASE MAINTENANCE. INFORMATION ON ORGANIC COMPOUND TASTE ODER & FISH TOXICITY ESTERON BRUSH KILLER TOXICITY TO FISH TASTE & ODOR 3A61-3. INSECTICIDES, RODENTICIDES, AND AGRICULTURAL POISONS61, 875-882). METHODOLOGY OF A REPRODUCTIVE STUDY OF WIVES OF DOW MI DIVISION EMPLOYEES POSSIBLY EXPOSED TO DIOXINS C T T L . POSSIBLE POISONING DUE TO CONSUMPTION OF SPRAYED FRUIT. NO REPORTS OF 245T TOXICITY IN MAN CTTL. 245T MILDLY IRRITATING TO SKIN OVER A LONG PERIOD OF TIME WITH DIRECT, INTIMATE CONTACT CTTL. SUSPECTS 245T POISONING IN PATIENT WITH PERIPHERAL NEUROPATHY, ASKS FOR INFORMATION AND HUMAN TISSUE TEST PROCEDURES. HOSPITA NUMBER DATE DOCUMENT 1432 03/25/65 AUTHOR: GAY HH ADDRESSEE: MICKLESON KNP COPYEE: DOW TYPE PAGES LETTER 1 PALMERSTON NORTH ROWE VK DOCUMENT 1433 06/20/66 LETTER AUTHOR: QUETSCH RM ADDRESSEE: DOW COPYEE: ia POISON INFO CENTER 1 DOCUMENT 1434 AUTHOR: DOW ADDRESSEE: COPYEE: 12/16/65 REPORT SCHABERG DE DOCUMENT 1435 AUTHOR: DOW ADDRESSEE GAY HH COPYEE: 11/11/59 TELEX PRIDDY JK DOCUMENT 1436 AUTHOR DOW ADDRESSEE: DOW COPYEE: 08/15/63 LETTER NIZIO LD GAY HH DOCUMENT 1437 06/14/63 AUTHOR: WILLARD G ADDRESSEE: DOW COPYEE: LETTER DOCUMENT 1438 08/20/63 AUTHOR: DOW ADDRESSEE: WILLARD G COPYEE: FLETCHER FW LETTER GAY HH MCCLURE F 1 DOCUMENT 1439 08/01/61 AUTHOR: LEVINSON B ADDRESSEE: DOW COPYEE: LETTER 1 fcCA-, to o to TITLE 245T NONTOXIC TO THE NERVOUS SYSTEM CTTL HOSPITA PAGE 206 QUESTIONING IF 245T COULD HAVE LEFT RESIDUAL OVER A LONG PERIOD OF TIME CTTL. EXPOSURES BETWEEN 540405 AND 640117 (245T) CTTL. REQUEST FOR TREATMENT OF SKIN IRRITATION ALLEGEDLY DUE TO ACCIDENTAL EXPOSURE TO MIXTURE OF REDDON AND CRUDE OIL CTTL. REQUEST FOR ASSISTANCE IN ANSWERING COMPLAINT OF WILLARD G OF SKIN RASH FROM REDDON CTTL. PENCE CB COMPLAINT OF ITCHING AND BURNING OF ARMS, FACE, HANDS AND LEGS ALLEGEDLY FROM USE OF REDDON CTTL. REPORT OF ALLEGED SKIN REACTION FROM EXPOSURE TO REDDON REQUIRES FURTHER DETAILS CTTL. NIZIO LD PENCE CB INQUIRY REGARDING TOXICOLOGICAL EFFECTS OF ESTERON CTTL. NUMBER DOCUMENT 1440 AUTHOR: DOW ADDRESSEE: COPYEE: DATE 09/21/65 TYPE PAGES TELECON 2 SCHARNWEBER HC DOCUMENT 1941 07/26/55 AUTHOR: DOW ADDRESSEE: COPYEE: G O R D O N HI WILLIAMS GJ REPORT ROWE VK HYMAS TA 3 DOCUMENT 1442 10/26/62 LETTER AUTHOR: EMPLOYERS MUTUAL LIABILI MULLINS GW ADDRESSEE: DOW ROWE VK COPYEE: 1 DOCUMENT 1443 11/02/62 LETTER 2 AUTHOR: DOW ROWE VK ADDRESSEE: EMPLOYERS MUTUALS OF WAS MULLINS GW COPYEE: DOW KOEHLINGER DG DOCUMENT 1444 11/03/61 AUTHOR: DOW ADDRESSEE: SNYDER G COPYEE: MEDREC GAY HH 1 DOCUMENT 1445 AUTHOR: DOW ADDRESSEE: DOW COPYEE: DOCUMENT 1446 08/21/59 TELEX VANHOUTEN R GAY HH 1 10/29/57 LETTER 2 AUTHOR: CHIPMAN CHEM ADDRESSEE: DREESSEN J COPYEE: REED LR NACA DOCUMENT 1447 07/17/57 AUTHOR: DOW ADDRESSEE: BUCHER WH COPYEE: DOW $ O o CO LETTER 2 ROWE VK CHILDRENS HOSPITAL GAY HH TITLE PAGE BOSTON POISON CONTROL CENTER, REPORT OF TELEPHONE INQUIRIES, ESTERON (WHICH FORMULATION NOT SPECIFIED). 207 NOTES REGARDING AN ILLNESS ALLEGEDLY INVOLVING ESTERON 245. SANFORD D SMITH HL COMMUNICATION CONCERNING CLAIM THAT 24D AND 245T SPRAYING CONTAMINATED DRINKING WATER SUPPLY CTTL. COMMUNICATION CONCERNING 24D AND 245T TOXICOLOGICAL INFORMATION CTTL. KRAMER CG WEEDONE POSSIBLE CAUSE OF AGRANULOCYTOSIS IN PREGNANT PATIENT CTTL. LETTER REQUESTING RECOMMENDED TREATMENT FOR 24D, 245T SPRAYING RELATED DERMATOLOGICAL TOXICITY CTTL. IN REFERENCE TO AM MOTORISTS INSURANCE CLAIM, REED SAYS THEY HAVE NOT ENCOUNTERED A BRONCHIAL REACTION TO 24D, 245T, AND MCP SPRAYS CTTL . 24D TOXICITY TO HUMANS CTTL. SOCIE NUMBER DATE DOCUMENT 1448 06/24/57 AUTHOR: DOM ADDRESSEE: K E I T H RL COPYEE: DOM GAY HH DOCUMENT 1449 06/26/57 AUTHOR: RUTLAND RAILMAY ADDRESSEE: DOM COPYEE: DOCUMENT 1450 03/17/66 AUTHOR: DOM ADDRESSEE: ETHERINGTON HALL COPYEE: DOM DOCUMENT 1451 AUTHOR: ADDRESSEE: COPYEE: 00/00/63 DOCUMENT 1452 02/00/55 AUTHOR: DOM ADDRESSEE COPYEE: DOCUMENT 1453 00/00/66 AUTHOR: DURHAM MF ADDRESSEE: COPYEE: DOCUMENT 1454 00/00/69 AUTHOR: ERICHSENJONES JR ADDRESSEE COPYEE: DOCUMENT 1455 06/22/67 AUTHOR: COOK FB ADDRESSEE: DOM COPYEE: DON >0 MOL F MA ro o TYPE PAGES LETTER 2 ROME VK RUTLAND RAILMAY ROME VK LAMRENCE AA LETTER ROME VK LETTER MILLER ME ONTARIO CAN BAKER G CHART REPORT HYMAS TA CHART 1 NASHINGTON ST UNIV REPORT 8 UN I V COL OF M A L E S ABE LETTER DOM GOMELL JH CLOSE GM TITLE PAGE 208 INFORMATION DENYING HEMOLYTIC ANEMIA ALLEGEDLY CAUSED BY HERBICIDES CTTL. C O N N E R DL COON ET A C K NOWLEDGEMENT OF RECEIPT OF TECHNICAL AR T I C L E S TO ASSIST IN CLAIMS CTTL. TOXICOLOGICAL PROPERTIES OF 245T CTTL. VALBERG LS BREMNER NW G ORDON HL TABLE A CRUDE FREQUENCIES AND RATES OR RATIOS PER 1000 LIVE BIRTHS OF PREGNANCY OUTCOMES ACCORDING TO DIOXINS EXPOSURE CATEGORIES CTTL. SUMMARY OF TOXICOLOGICAL INFORMATION ON 24D AND 245T TYPE HERBICIDES AND AN EVALUATION OF THE HAZARDS TO LIVESTOCK ASSOCIATED WITH THEIR USE. ROWE VK ESTIMATED RELATIVE ACUTE TOXICITY HAZARD OF PESTICIDES TO SPRAYMEN. WOLFE HR FISH AND RIVER POLLUTION (FISH TOX, 128-141). :RYS N O R F O L K 8 W E S T E R N R A I L W A Y E S T E R O N 245 OS. GORDON HL SHELDON HW NUMBER DATE DOCUMENT 1456 11/19/58 AUTHOR: DOW ADDRESSEE: GRINVALSKY HT COPYEE: DOW TYPE PAGES TITLE PAGE 209 LETTER 2 TOXICOLOGICAL INFORMATION ON MCP AMINE MEED KILLER AND ESTERON 99 CTTL. WOLF MA ST MICHAELS HOSPITAL WOLF MA DOCUMENT 1457 05/26/67 AUTHOR: DOW ADDRESSEE: MCNAMARA BP COPYEE: DOW LETTER ROWE VK US ARMY ROWE VK 2 TRANSMITTAL OF INFORMATION ON TORDON 101 AND ISOPROPANOL AMINE CTTL. HAMMER OH DOCUMENT 1458 05/00/66 AUTHOR DOW ADDRESSEE: PRESCOTT C COPYEE: LETTER 2 SAFETY FACTS ABOUT ESTERON 245 OS, ESTERON 245 CONCENTRATE AND ESTERON BRUSH KILLER OS CTTL. WOLF MA VERMONT ELECTRIC COOPERA DOCUMENT 1459 AUTHOR: DOW ADDRESSEE:: DOW COPYEE: DOW MARTIN 11/12/63 FB LETTER ROWE VK C O U L T E R LL ROWE VK 2 LIABILITY CLAIM ON ESTERON 245 OS. KOOHLINGER DO LYNN GE DOCUMENT 1460 12/13/56 AUTHOR: COON ET ADDRESSEE DOW COPYEE: DOW LETTER DOW ROWE VK ALLEN WW 1 MR H.F. HILTON, P U B L I C S E R V I C E C O M P A N Y OF IN, P L A I N F I E L D IN. BENDALL TL CORBIN WL DOCUMENT 1461 09/13/56 MINUTES AUTHOR: DOW ADDRESSEE CHEMI TROL CHEM COMPANY COPYEE: DOW ROWE VK KARLEVETZ F ROWE VK 2 RESPONSE TO GRIFFITH COMPLAINT INCLUDING OPINION THAT DESCRIBED CONTAMINATION MAY BE RESPONSIBLE CTTL. C O N N E R DL MCCOY MJ DOCUMENT 1462 08/14/55 LETTER AUTHOR: DOW ROWE VK ADDRESSEE: GRAVENS AND HALK COMPANY GRAVENS J COPYEE: DOW ROWE VK SMITH HL WILLIAMS GJ ALLEGED ILLNESS DUE TO 245T SPRAYING CTTL. GORDON H SANFORD D DOCUMENT 1463 06/15/54 LETTER AUTHOR: CONSUMERS POWER COMPANY ADDRESSEE: DOW $ COPYEE: -C. r o Ld o 0 or ONEIL RH ROWE VK RESULTS OF PATCH TEST SHOWS NO ALLERGIC REACTION TO ESTERON 245T CTTL. STENBERG JN NUMBER DATE TYPE PAGES DOCUMENT 1464 06/10/54 LETTER 1 AUTHOR: CONSUMERS POWER COMPANY WOODRUFF JT ADDRESSEE DOW MCCUTCHEON SD COPYEE: JOHNSON JC SANFORD D TITLE PAGE 210 NO REACTION TO ESTERON 245 IN DERMATOLOGIST'S TEST ON CONSUMER POWER EMPLOYEE CTTL. S M I TH HL WILLIAMS GJ DOCUMENT 1465 AUTHOR: DOW ADDRESSEE! COPYEE: 08/26/64 MEMO TELECON WOLF MA 1 MAX COOLEY CLAIMS AGENT, LONG DISTANCE PHONE CALL. DOCUMENT 1466 09/28/60 LETTER 2 AUTHOR: BECKWITH C ADDRESSEE: CONTINENTAL INSURANCE COPYEE: ASHWORTH RH DOW DAVIS DD KARL KUEMMERLING INC LETTER CONCERNING COMPLAINT CATTLE MORTALITY CTTL. KMEMMERLING INC AGAINST 24D AND KMEMMERLING K 245T TYPE HERBICIDE AND DOCUMENT 1467 01/05/60 AUTHOR: KLAUDER JV ADDRESSEE-* DOW COPYEE: LETTER ROWE VK 2 LETTER FROM JV KLAUDER TO VK ROWE CONCERNING DOW M-1500 AND DDOW ET-394 CTTL. DOCUMENT 1468 12/09/59 AUTHOR: KLAUDER JV ADDRESSEE: DOW COPYEE: LETTER ROWE VK 1 LETTER TO VK ROWE FROM JV KLAUDER REGARDING M-1500 AND ET-394 CTTL. DOCUMENT 1469 10/14/59 AUTHOR: DOW ADDRESSEE: KLAUDER JV COPYEE: DOW LETTER ROWE VK ROWE VK 1 LETTER SUGGESTING SKIN TESTS BE DONE USING DOW ET-394 AND DOW M-1500 CTTL. OLSON KJ DOCUMENT 1470 05/13/69 AUTHOR: DOW ADDRESSEE: CHAMBERLAIN SV COPYEE: DOCUMENT 1471 AUTHOR: DOW ADDRESSEE: CARSON COPYEE: i DOW WELDEN 07/05/60 DJ L LETTER 2 WOLF MA OM SCOTT 8 SONS HEALTH HAZARDS FOR THE HANDLING OF 24D, FORMULA 40 AND KURON CTTL. LETTER 2 24D SHOULD NOT INCREASE SUSCEPTIBILITY TO RESPIRATORY DISEASES CTTL WIFFEN EE VANWATERS 8 ROGERS OF CA BAIRD GK KENNAN JD RITTY PM WILSON JB WOLF MA Z h -(T , ro o 05 NUMBER DOCUMENT 1472 AUTHOR: DOW ADDRESSEE: DOW COPYEE: DOW DATE 06/15/60 TYPE PAGES LETTER RITTY PM NORRIS MG C O U L T E R LL 1 DOCUMENT 1473 AUTHOR: DOW ADDRESSEE: DOW COPYEE: DOW 12/04/56 LETTER ROWE VK MCCOMB JR ROWE VK 1 DOCUMENT 1474 04/17/58 AUTHOR: DOW ADDRESSEE: COPYEE: DOW COLBY RW JOHNSON JE NORTON TR SPALDING J REPORT 3 STEVENSON GT BARRONS KC C O U L T E R LL KAGY JF NUTTING HS VANVALKENBURG JW DOCUMENT 1475 AUTHOR: DOW ADDRESSEE: DOW COPYEE- DOW 12/11/57 LETTER LYNN GE HYMAS TA COULTER LL 1 DOCUMENT 1476 12/14/61 AUTHOR: DOW ADDRESSEE: RISKEN AND HERRON COPYEE: DOW LETTER ROWE VK RISKEN JH ROWE VK 2 DOCUMENT 1477 05/19/53 AUTHOR: DOW ADDRESSEE: MAJOR GB COPYEE: DOW LETTER 2 ROWE VK MO ST HIGHWAY DEPT CRAIN HD DOCUMENT 1478 05/15/53 AUTHOR: DOW ADDRESSEE: HUMES MF COPYEE: BALL HR LETTER MULLISON WR INTL PACKERS MCCASKEY DB 2 Q<ob -(C, DOCUMENT 1479 05/01/53 AUTHOR: CRAIN HD ADDRESSEE: DOW COPYEE: DIETZEL AL 1 ro '~ -I LETTER 1 DOW ROWE VK MO ST HIGHWAY DEPT TITLE PROPOSAL FOR TESTS ON M-1845 CTTL PAGE 211 FLETCHER FH BRUSH KILLER TX IN NO. 2 FUEL OIL. BENDALL TL COON ET INVERTON (BRUSH KILLER) HAY SPRAY CATTLE FEEDING TEST. BLAIR EH GREEN J LIPPIE LJ PERKINS RP BOUNDY RH HYMAN TA LYNN GE ROWE VK PLANS FOR TOXILOGICAL STUDY USING INVERTON CTTL. JOHNSON JE ROWE VK INFORMATION ON THE TOXICITY OF 2AD 245T TOWARD HUMANS CTTL. KOEHLINGER D INFORMATION CONCERNING SKIN IRRITATION OF 24D & 2A5T FORMULATIONS CTTL. 1 DIETZEL AL SMITH HL INFORMATION REPLY ABOUT ESTERON BRUSH KILLER CAUSING NAUSEA IN AN EMPLOYEE CTTL. WOLF MA REQUEST FOR INFORMATION ON 24D 8 245T REGUARDING SKIN EXPOSURE OF ONE OF THEIR EMPLOYEES CTTL. NUMBER DATE DOCUMENT 1ABO 07/22/52 AUTHOR: DON ADDRESSEE HARVEY JT COPYEE: DON DOCUMENT 1A81 02/18/52 AUTHOR SIMSON HA ADDRESSEE COPYEE: DOCUMENT 1A82 AUTHOR: DON ADDRESSEE DON COPYEE: 02/01/52 DOCUMENT 1A83 AUTHOR: DON ADDRESSEE: DON COPYEE: 02/22/61 DOCUMENT 1A8A 09/13/56 AUTHOR: DON ADDRESSEE CHEMITROL COPYEE DON DOCUMENT 1A85 09/30/55 AUTHOR DON ADDRESSEE CHEMITROL COPYEE: DON HYMAS TA DOCUMENT 1A86 08/0A/55 AUTHOR: DON ADDRESSEE COPYEE DON LEASURE K TYPE PAGES LETTER 1 SOUTHNICK L LYON CHEM RONE VK ROC 2 LETTER RONE VK SMITH HL 2 LETTER A NOLF MA OUELLETTE FE LETTER RONE VK KARLEVETZ F RONE VK 2 LETTER RONE VK KARLEVETZ F ROHE VK 5 REPORT RONE VK BARRONS KC NORTON TR 5 TITLE PAGE 212 TOXICITY OF NEW ESTERS IS NOT SIGNIFICANTLY DIFFERENT THAN THE OLD ESTERS CTTL. WALLBERG J LOCAL SPORTS WRITER ACCUSES ESTERON 245 USED BY PA POWER & LIGHT ON RIGHT OF WAY OF KILLING RABBITS(CHEMICAL SALESMAN'S CALL REPORT) CTTL . REQUEST OF TOXIC INFORMATION FOR 5 DIFFERENT HERBICIDES C TTL. TOXICOLOGICAL INFORMATION ON A NUMBER OF PRODUCTS SUITABLE FOR APPLICATION FOR REGISTRATION IN ZEALND. HIGH LEVELS OF ESTERON 10 10 AND ESTERON 245 FOUND IN STREAM CAUSE MORTALITY OF FISH CTTL. CONNER DL MCCOY KW POISONING CASE IN JASPER, IN SEEMS TO BE UNRELATED TO SPRAYING OF ESTERON BRUSH KILLER CTTL. BRYANT CA CONNER D INFORMATION RELATIVE TO ILLNESS TO CATTLE ON THE ALBERT SCHMUCKER FARM THREE MILES NORTH OF HARBOR BEACH MI. HYMAS TA WILLIAMS GJ JOHNSON JE NUMBER DATE TYPE PAGES DOCUMENT 1487 02/04/68 LETTER 2 AUTHORi ASST COUNTY AGENT CHARLO BARBOUR K ADDRESSEE BERRY R STATE CHEMIST COPYEE TITLE PAGE 213 BARBOUR REQUESTS INFORMATION ON THE INGREDIENTS IN 24D AND 245T THAT MAY HAVE CAUSED RESPIRATORY ILLNESS TO HIS WIFE CTTL. DOCUMENT 1488 04/16/58 AUTHOR DOW ADDRESSEE ADLEY FE COPYEE DOW LETTER ROWE VK HANFORD ROWE VK 2 TOXICITY INFORMATION ON TAKE IF EXPOSURE IS FOR ATOMIC PRODUCTS ESTERON 44 TO HUMANS AND PROLONGED PERIODS CTTL. PRECAUTIONS TO DOCUMENT 1489 08/23/57 AUTHOR ADDRESSEE DARGER RJ COPYEE LETTER DOW TOXICITY INFORMATION ON ESTERON 44 AND ESTERON 245 SUITABLE FOR TRANSMITTAL TO ATTORNEYS IN THE CASE OF RADEL VERSUS DOW CTTL. DOCUMENT 1490 AUTHOR DOW ADDRESSEE DOW COPYEE DOW 08/05/59 LETTER ROWE VK MUNSON NH ROWE VK ALLEGED INJURY TO CATTLE FROM THE USE OF DOW ESTERON 245 BRUSH KILLER CTTL. DOCUMENT 1491 AUTHOR DOW A D D R E S S E E : DOW COPYEE 08/03/59 LETTER MUNSON NH ROWE VK ALLEGED INJURY TO CATTLE FROM THE USE OF DOW 245 ESTERON BRUSH KILLER CTTL. DOCUMENT 1492 AUTHOR DOW ADDRESSEE DOW COPYEE DOW WIFFEN 07/17/62 EE LETTER LYNN GE JOHNSON J MCINTYRE HH WILTSE M PERMITS FOR THE AQUATIC USE OF KUROSAL SL CTTL. RITTY PM ROWE VK DOCUMENT 1493 02/08/61 AUTHOR ADDRESSEE COPYEE rf*. O o CD DOW DOW BARRONS KC C O U L T E R LL FLETCHER RO GIBSON JW LEASURE JK MCCOY WJ RAYNOR RN SEEKER B REPORT 10 RITTY PM RITTY PM COLBY RW DOSSER RC FOSTER TS GREENFIELD JE LUTZ EM MCINTYRE HH ROHE VK si-irrii m SUMMARY OF AQUATIC HERBICIDE INFORMATION ON KUROSAL SL CM-1845) AND KUROSAL G (M-1847), ACD STATUS REPORT, DOCUMENT 21529 (FOR DOW PERSONNEL ONLY NOT FOR OUTSIDE DISTRIBUTION). ACD CIRCULATION C O N N E R DL FALSEY WP FURMAN FS HAMMER OH LYNN GE MULL ISON WR SAUNDERS ES SPAI. !'I !IG .11. ALLEN WW CORBIN WL FISHER JR G ANTZ RL JOHNSON JE M A R T U C H LL NATION HA SCHWARTZBECK f.UPOr n>! pv; RA 5*t NUMBER DATE SWEZEY AW WATSON AJ DOCUMENT 1494 AUTHOR DOW ADDRESSEE DOW COPYEE DOW 09/28/59 DOCUMENT 1495 AUTHOR DOW ADDRESSEE DOW COPYEE DOW 09/23/60 DOCUMENT 1496 06/11/51 AUTHOR CORBIN WL ADDRESSEE COPYEE DOW DOCUMENT 1497 01/07/63 AUTHOR ADDRESSEE COPYEE DOW AG RES SERVICE DOW GORDON HL SUNDERLAND WW DOCUMENT 1498 AUTHOR DOW ADDRESSEE DOW COPYEE DOW LUTZ E 12/13/61 DOCUMENT 1499 AUTHOR DOW ADDRESSEE DOW COPYEE DOW 04/02/62 DOCUMENT 1500 AUTHOR DOW ADDRESSEE DOW COPYEE DOW 05/22/59 TYPE PAGES TRUCHELUT GB WIFFEN EE LETTER JOSEPHS MJ ROWE VK LYNN GE 1 LETTER ROWE VK MAXWELL JL ROWE VK 2 ROC DOW ROWE VK 2 LETTER REPORT ROWE VK SCHOUBOE PJ RONE VK KOEHLINGER DG 5 LETTER ROWE VK MCCOY WJ ROWE VK R E E D DL 1 LETTER REED DL WALLBERG JB MCCOY WJ 1 LETTER WOLF MA IRVINE M WOLF MA 2 TITLE VANVALKENBURG JW WILSON JS WARDEN RL WILTSE MC PAGE 214 M-1500 HANDLING HAZARD STUDIES AND SKIN SENSITIZATION TESTS TO BE INITIATED CTTL . TOXICOLOGICAL INFORMATION ON SILVEX AND GARLON CTTL. STAMFORD WATER COMPANY (CHEMICAL SALESMAN'S CALL REPORT). COMPLAINTS CONCERNING DONPON CTTL. USDA ALLEN WW LEARY JS JR GAY HH LYNN GE KURON SORDONI CONSTRUCTION CO MPANY OF KINGSTON PA. JOHNSON JE WALLBERG JH KOEHLINGER D SOND O N C O N S T R U C T I O N C O M P A N Y K I N G S T O N PA. RITTY PM TOXICOLOGICAL INFORMATION ON KURON FOR OUTSIDE DISTRIBUTION. ROWE VK NUMBER DATE DOCUMENT 1501 01/02/59 AUTHOR: DOW ADDRESSEE KLAUDER JV COPYEE-- DOW TYPE LETTER ROWE VK ROWE VK PAGES 2 DOCUMENT 1502 12/05/58 LETTER AUTHOR: DOW ROWE VK ADDRESSEE HOSPITAL OF THE UNIV OF KLIGMAN AM COPYEE: DOW ROWE VK DOCUMENT 1503 12/01/58 AUTHOR DOW ADDRESSEE HYMAS TA COPYEE: DOW ROWE VK LETTER LYNN GE C O U L T E R LL DOCUMENT 1504 12/01/58 AUTHOR: DOW ADDRESSEE DOW COPYEE! DOW MCINTYRE HH LETTER 1 LENG ML GETZENDANER ME C O U L T E R LL ROWE VK DOCUMENT 1505 12/01/58 AUTHOR DOW ADDRESSEE: DOW COPYEE: DOW MCINTYRE HH LETTER LYNN GE ROWE VK COULTER LL 1 DOCUMENT 1506 10/10/58 AUTHOR! C O U L T E R LL ADDRESSEE: DOW COPYEE: MCINTYRE H LETTER DOW ROWE VK OTIS CE 1 DOCUMENT 1507 AUTHOR: DOW ADDRESSEE* DOW COPYEE: DOW CONNER 01/31/58 DL I LETTER ROWE VK C O U L T E R LL ROWE VK FLETCHER FW 3 o "A TITLE PAGE 215 LETTER REGARDING SKIN IRRITATION AND SKIN SENSITIZATION STUDY ON HUMANS WITH KURON CTTL. DISCUSS THE POSSIBILITY OF AM KLIGMAN ON DOING SKIN IRRITATION AND SKIN SENSITIZATION STUDY ON HUMANS WITH KURON CTTL. TOXICITY TEST ON LIVESTOCK AND CHICKENS USING KURON IN DRINKING WATER CTTL. JOHNSON JE MCINTYRE HH OBJECTIVE TO FIND OUT IF FISH AQUIRE THE CONCENTRATION OF SILVEX PRESENT IN THE WATER OR CONCENTRATE IT CTTL. HYMAS TA JOHNSON JE REQUEST FOR WORK TO EVALUATE THE SAFETY OF KURON AS AN AQUATIC HERBICIDE CTTL. HYMAS TA JOHNSON JE REACTION OF SWIMMERS TO KURON. KURON FOR AQUATIC WEED CONTROL. BARRONS KC IRISH DD BRITTON JW r 1ER u u C U M E ni 15Utt AUTHOR: ADDRESSEE: DOM COPYEE: DOM DATE 10/08/57 TYPE LETTER PAGES 1 ROME VK DAVIDSON JH TITLF AGP 16 EVALUATION OF USE HAZARDS IN CONJUNCTION HITH AQUATIC MEED CONTROL MITH KURON. FLETCHER FM DOCUMENT 1509 01/18/67 AUTHOR: IRISH DD ADDRESSEE: COPYEE: PRESENT 28 A T A L K G I V E N BY DR. DON D. IRISH IN B I O C H E M I C A L R E S E A R C H D E P ARTMENT CONFERENCE ROOM, 1701 BUILDING, ON 670118. DOCUMENT 1510 AUTHOR: ADDRESSEE COPYEE: 08/00/69 CHART REPORT 3 TOXICITY OF 29D AND SILVEX COMPOUNDS TO BIRDS IN DIETS(SA3.00 ISOOCTYL ESTERS, SILVEX BEG). DOCUMENT 1511 00/00/53 REPORT AUTHOR: ADDRESSEE: COPYEE: BASF MGERM FLEIG I UNIVERS ITAT DUSSELDORF H 9 CHROMOSOMENANALYSE BEI MITARBEITERN MIT EXPOSITION GEGENBER TCDD (UNFALLGESCHEHEN AM 531117). GOLDMANN P ROHRBORN G DOCUMENT 1512 AUTHOR: ENG ADDRESSEE: COPYEE: 01/29/67 REPORT 9 CHEMICAL COMPOUNDS USED IN AGRICULTURE AND FOOD STORAGE(RECOMMENDATIONS FOR SAFE USE IN GREAT BRITAIN)C295T)(A HERBICIDE)(HOME GARDEN USE)(MINISTRY OF AG, FISHERIES AND FOOD, PEST BRANCH). MINISTRY OF AG FISHERIES DOCUMENT 1513 08/09/55 AUTHOR: BARRONS KC ADDRESSEE: COPYEE: ABSTRACT DOM 3 RESUME OF NEM ADVANCES IN AGRICULTURAL RESEARCH-FIELD RESEARCH (AGRICULTURAL CHEMICAL REASEARCH AND DEVELOPMENT SEMINAR MIDLAND, MI )(ROI 9895). DOCUMENT 1519 AUTHORi DOM ADDRESSEE: COPYEE: 08/15/50 REPORT 5 MCCOLLISTER DD THE ACUTE ORAL TOXICITY OF 295T TO RATS, MICE, GUINEA PIGS AND CHICKS. ROME VK SPENCER HC 0 bi TO o ro > v.i B DOCUMENT 1515 08/00/50 AUTHOR: DON ADDRESSEE: COPYEE: DOCUMENT 1516 07/17/60 AUTHOR: DRILL VA ADDRESSEE: COPYEE: DOCUMENT 1517 03/09/49 AUTHOR: WHITE L ADDRESSEE: COPYEE: DOCUMENT 1518 AUTHOR: ADDRESSEE: COPYEE: 12/27/49 DOCUMENT 1519 AUTHOR: DOW ADDRESSEE: COPYEE: 11/00/49 DOCUMENT 1520 08/23/50 AUTHOR: DOW ADDRESSEE: DOW DOSSER RC LYNN GE COPYEE: DOCUMENT 1521 08/15/78 AUTHOR: BECKWITH C ADDRESSEE: COPYEE: DOCUMENT 1522 AUTHOR: NACA ADDRESSEE: COPYEE: 00/00/66 E REPORT ROWE VK ..,,ES 6 REPORT 14 WAYNE UNIV REPORT 5 REPORT 22 REPORT 4 MCCOLLISTER DD REPORT 4 ROWE VK ALLEN WW DUTTON WC SUNDERLAND WW MEMO DOW 1 REPORT 6 NY ST EXP STATION -J to co P TESTIMONY TO BE PRESENTED AT THE FOOD AND DRUG ADMINISTRATION RESIDUE TOLERANCE HEARING FOR FRESH FRUITS AND VEGETABLES, 500800 (TOXICITY OF 245T). ACUTE AND SUBACUTE ORAL TOXICITY OF 245T FOR DOGS. 245T (K NUMBER 4568-4 BIOCHEM FILE T23K4-23-2). 245T (X NUMBER 4568-4 BIOCHEM FILE T2314-23-3). THE ACUTE ORAL TOXICITY OF 245T TO RATS, MICE, GUINEA PIGS AND CHICKS. ROWE VK SPENCER HC RESULTS OF TOXICOLOGICAL TESTS ON 245T. BRITTON IRISH DD BRITTONS DIV KAGY JF DIAMOND SHAMROCK CLEVELAND, OH RON DEZEMBER 660000 ANNUAL REPORT PHENOXY HERBICIDES IN PASTURE AND RANGELAND OR ALONG ROADSIDES. NUMBER DOCUMENT 1523 AUTHOR: NACA ADDRESSEE: COPYEE: DATE 00/00/66 3 DOCUMENT 1524 AUTHOR: DOW ADDRESSEE: COPYEE: 09/28/65 DOCUMENT 1525 02/26/65 AUTHOR: GROTH DH ADDRESSEE: THA COPYEE: DOCUMENT 1526 AUTHOR: ADDRESSEE: COPYEE: 08/02/67 1 DOCUMENT 1527 AUTHOR: ADDRESSEE: COPYEE: 06/02/67 DOCUMENT 1528 AUTHOR: ADDRESSEE: COPYEE-' 10/02/67 DOCUMENT 1529 AUTHOR: ADDRESSEE: COPYEE 05/12/67 DOCUMENT 1530 AUTHOR: DOW ADDRESSEE: COPYEE: 03/10/65 TYPE REPORT PAGES 25 CHART OHARE C 1 LETTER HEW UPTON ET REPORT 1 9 REPORT 2 REPORT 2 REPORT TEST 2 REPORT 17 SILVERSTEIN LG 0 ih - g >* to Hr* NU TITLE PAGE 218 TOXICOLOGY. ACUTE STUDIES. ORAL AND INTRAPERITIONEAL ADMINISTRATION RATS, MICE, GUINEA PIGS, RABBITS, AND MONKEYS; INTRAVENOUS ADMINISTRATION RABBITS. TOXICOLOGICAL RESULTS OF APPLIED TORDON 101, WEEDAR 245T AMINE, VEON 245T AND VEON BRUSH KILLER CTTL. 570000 DERMATOLOGICA ARTICLE BY KIMMIG REPRESENTS PRESENT HEW KNOWLEDGE OF TOXICITY OF 245T AND ITS TOXIC CONTAMINANTS CTTL. METHODS AND RESULTS IN TESTING SEVERAL DIFFERENT LAB ANIMALS CTTL. TCDD SINGLE DOSE ORAL TOXICITY TO RATS. TCDD SINGLE DOSE ORAL TOXICITY TO MALE GUINEA PIGS. TCDD SINGLE DOSE ORAL TOXICITY TO MALE GUINEA PIGS. THE CHLORACNE PROBLEM BIOCHEM'S CONTRIBUTION. NUMBER DOCUMENT 1531 AUTHOR: DOM ADDRESSEE: COPYEE: DATE 00/00/69 TYPE CHART MEMO PAGES 1 DOCUMENT 1532 AUTHOR: ADDRESSEE: COPYEE: 00/00/69 MEMO DOCUMENT 1533 04/06/65 LETTER 2 AUTHOR: ADDRESSEE: COPYEE: DOM DOM DOM STEARNS JCH OTIS CE COON ET HOLDEMAN GE THAYER G DOCUMENT 1534 10/17/57 AUTHOR: ALLAN PF ADDRESSEE DOM COPYEE: DOM LETTER CORNELL MRIGHT ML BORELL AE 1 DOCUMENT 1535 04/00/69 REPORT 12 AUTHOR: ADDRESSEE: COPYEE: BUR OF COMMERCIAL UNIV OF MD FISHER DAVIS HC DOCUMENT 1536 00/00/68 REPORT 14 AUTHOR: ADDRESSEE: COPYEE: BATES RR GART JJ LITTON INDUS PETERS J BIONETICS HART ER MITCHELL I PETRUCELLI L DOCUMENT 1537 AUTHOR: DOM ADDRESSEE: COPYEE: 08/00/68 CHART 2 "5 h-* cn TITLE PAGE 219 TABLE OF RESULTS OF 245T AMD TRICHLOROPHENOL TOXICITY TESTS CTTL. CHRONOLOGY OF CHLORACNE TESTING IN A R L . SPECIFICATIONS ALLOWING NIL AMOUNTS OF ACNEGFN IN 245T SHOULD BE RIGIDLY ADHERED TO IN ORDER TO AVOID PRESENTING A SERIOUS HEALTH HAZARD TO THE PUBLIC CTTL. C O U L T E R LL HUTCHENREUTHER C MULHOLLAND R ROWE VK AQUATIC WEED TREATMENTS(ROI 13861) CTTL. WILTSE MG EFFECTS OF PESTICIDES ON EMBRYONIC DEVELOPMENT OF CLAMS AND OYSTERS AND ON SURVIVAL AND GROWTH OF THE LARVAE (FISHERY BULLETIN 67(2), 393-404). HIDU H U.S. FISH & WILDLIFE SER BIOASSAY OF PESTICIDES IN MICE; A PRELIMINARY 1101-1114, 690600). FALK HL INNES JRM NATL CANCER INST ULLAND BM AND INDUSTRIAL CHEMICALS FOR TUMORIGENICITY NOTE (JOUR OF NATL CANCER INST, 42(6), FISHBEIN L KLEIN M PALOTTA AJ VALERIO MG DOWICIDE PRODUCT SAMPLES HUMBER DOCUMENT 1538 AUTHOR: DOW ADDRESSEE: COPYEE: DATE 03/21/69 TYPE PAGES REPORT 8 HOYLE HR DOCUMENT 1539 05/00/69 AUTHOR: SILVERSTEIN LG ADDRESSEE" DOW COPYEE: CHART DOW FERNANDEX JB 1 DOCUMENT 1540 AUTHOR: ADDRESSEE: COPYEE: 00/00/68 REPORT 25 DOCUMENT 1541 00/00/69 REPORT AUTHOR: MONKS WOOD EXP STATION E WAY JM ADDRESSEE COPYEE: 26 DOCUMENT 1542 00/00/68 AUTHOR: BATES RR HOGAN MD ADDRESSEE: COPYEE: REPORT COURTNEY KD MITCHELL I 14 DOCUMENT 1543 02/21/69 AUTHOR: TSCHIRLEY FH ADDRESSEE: COPYEE: REPORT USDA 8 DOCUMENT 1544 00/00/68 AUTHOR: EDWARDS NT ADDRESSEE: COPYEE: ABSTRACT 1 OAK RIDGE NATL LAB DOCUMENT 1545 00/00/67 AUTHOR CHEM ABSTRACTS ADDRESSEE: COPYEE: ABSTRACT DERMER OC 1 V Z h -(^ to h-* 05 TITLE PAi>^ 220 CHLORACNE PROBLEM AT FORT SASKATCHEWAN P L A N T , DON CAN. RESEARCH LABORATORY FILE T21-18-2. SILVERSTEIN LG BIOCHEMICAL BIOCHEMICAL RESEARCH RABBIT EAR TESTING OF CERTAIN DOWICIDES FOR CHLORACNE PRODUCING ACTIVITY CTTL. CHLORACNE DOM EXPERIENCE. TOXICITY AND HAZARDS TO MAN, DOMESTIC ANIMALS, AND WILDLIFE FROM SOME COMMONLY USED AUXIN HERBICIDES (RESIDUE REVIEWS 26, 37-62). TERATOGENIC EVALUATION OF 245T. FALK HL GAYLOR DW NATL CANCER INST NIEHS DEFOLIATION IN VIETNAM (SCIENCE 163, 779-786). METABOLISM OF HERBICIDES IN ECOSYSTEMS (U.S. AT ENERGY COMM 6 7 0 0 0 0 K N U C L SCI ABSTR 22(8), 14913). VANDYNE GM EFFECT OF THE HERBICIDE 245T ON BREEDING BIRD POPULATIONS (PROCEEDINGS OK ACAD SCI 46, 2 3 5 - 7 H C H E M ABSTRACTS 67). MARTIN RP OK ST UNIV NUMBER DOCUMENT 1546 DATE 00/00/63 TYPE ABSTRACT PAGES 1 AUTHOR: DAVIS JT ADDRF3SEE: COPYEE: HUGHES JS DOCUMENT 1547 00/00/62 ABSTRACT 1 AUTHOR: ADDRESSEE: COPYEE: ANDERSON A KIVIMAE A CHEM ABSTRACTS WADNE C DOCUMENT 1548 00/00/60 ABSTRACT 1 AUTHOR: BODENSTEIN G ADDRESSEE: COPYEE: CHEM ABSTRACTS DOCUMENT 1549 11/14/55 LETTER AUTHOR: MUNICIPAL HOSPITAL KASSE SCHMIDT ADDRESSEE: BOEHRINGER KNECHT COPYEE: WILDHIRT 3 DOCUMENT 1550 02/13/68 AUTHOR: ALFORD HG ADDRESSEE:' DON COPYEE: LETTER USDA 1 DOCUMENT 1551 12/08/64 REPORT 14 AUTHOR: ADDRESSEE: COPYEE: SKELLY NE BRADLEY KB GILL HH HESS TM KALLOS GJ NORTON TR ROWE VK SHRADER SA TRAPP WB WRIGHT N COULTER KE GOERGEN GG HOLMES RD KEY M NYQUIST RA SAUERS RC SILVERSTEIN WALKER RE L TITLE PAGE 221 FURTHER OBSERVATIONS ON THE TOXICITY OF COMMERCIAL HERBICIDES TO BLUEGILL S U N F I S H ( P R O C E E D I N S S O U T H E R N W E E D C O N F 16, 337-60)(BIOCHEMISTRY). LA WILDLIFE & FISHERIES LEGATSKI E THE TOXICITY OF SOME HERBICIDES TO CHICKS (KGL LANTBRUKSHOGSKOL OCH STATENS LANTBRUKSFORSOK STATENS HUSDJURSFORSOK SARTRYCK OCK FORHANDSMEDD 155, 1 8 H C H E M ABSTRACTS 39). DAHL S INST TECH TOXICITY OF PRESENT DAY PESTICIDES FOR FISH. THE TOXICITY OF SOME HERBICIDES TO FISH (Z P F L ANZENKRANKH U PFL A N Z E N S C H U T Z 67, 1 5 0 - 3 M C H E M ABSTRACTS 53). G R E E N EL MULLERBASTGEN G SUMMARY OF OBSERVATIONS OF SIX CASES OF TRICHLOROPHENOL INTOXICATION CTTL. ESTERON T6 OS USDA REG 666-220 YOUR LETTER OF 680102. ISOLATION AND IDENTIFICATION OF POSSIBLE ACNEGENS FROM THE CAUSTIC INSOLUBLE PORTION OF THE PRODUCTS FROM THE 265-TRICHL0R0PHEN0L PROCESS 1 (REPORT ALS 57-676). DELISLE NG GREENE LM HOYLE HR LUCE EN OLSON KJ SCHLTEN HG SWIM LE WESTOVER LB DOW HABERSTROH JOHNSON RL LUECK AF POTTS WJ SEXTON AR THORSBERG TF W1DIGER AH NUMBER DATE DOCUMENT 1552 00/00/57 AUTHOR KIMMIG J ADDRESSEE-- DOM COPYEE: DOCUMENT 1553 04/06/65 AUTHOR: DOM ADDRESSEE-- DOM COPYEE: DOM STEARNS JCH DOCUMENT 1554 AUTHOR: DOM ADDRESSEE: DON COPYEE: DON 07/25/67 DOCUMENT 1555 05/20/65 AUTHOR: TIFFANY PA ADDRESSEE: COPYEE: DOCUMENT 1556 04/14/65 AUTHOR: DOM ADDRESSEE: DON COPYEE: DOM HUTCHENREUTHER C DOCUMENT 1557 03/28/57 AUTHOR: DOM ADDRESSEE COPYEE: CHRI S T I A N HJ HILLIAMS RT DOCUMENT 1558 AUTHOR: ADDRESSEE: COPYEE: 07/29/64 TYPE PAGES REPORT 6 SCHULZ KH TORKELSON T LETTER OTIS CE COON ET HOLDEMAN GE THAYER G 2 LETTER ROME VK MCCOY NJ ROHE VK 1 TEST 7 LETTER 1 MULHOLLAND RS OTIS CE COON ET ROHE VK REPORT RAYNOR RN HILL JM 2 LETTER 2 1 to 00 TITLE PAi>_ OCCUPATIONAL CHLORACNE CAUSED BY AROMATIC CYCLIC ETHERS (DERMATOLOGICA 115 (A) 5A0-5A6). 2cc ESTABLISHING SPECS FOR 1 PPM MAXIMUM OF ACNEGEN IN 2A5T AND OTHER DOM TRICHLOROPHENOL PRODUCTS CTTL. COULTER LL HUTCHENREUTHER C MULLHOLLAND RS ROHE VK 2A5T FORMULATIONS. CORBIN ML THE DETERMINATION OF TCDD IN 2A5T BY GAS LIQUID CHROMATOGRAPHY. REQUEST FOR SPECIFICATIONS ON PRODUCTS MADE FROM TCP CTTL. COULTER LL TRAYER G HOLDEMAN CE RANGE MANAGEMENT RESEARCH (ROI 6207). PRENDERGAST DT UNDERHILL RH EVALUATION OF DATA FOR HR REGISTRATION FOR 24D AND 2A5T ON BLUEBERRIES SUBMITTED BY DOM 6A0715. NUMBER DOCUMENT 1559 DATE 09/12/68 TYPE REPORT PAGES 6 AUTHOR) DON ADDRESSEE: COPYEE: DOCUMENT 1560 AUTHOR! ADDRESSEE! COPYEE: 07/00/58 DOCUMENT 1561 07/28/58 AUTHOR: M C F A R L A N D FJ ADDRESSEE: COPYEE: I DF I RSR DOCUMENT 1562 AUTHOR: DOW ADDRESSEE: USDA COPYEE: 02/24/49 DOCUMENT 1563 04/25/67 AUTHOR: ADDRESSEE: COPYEE: WIDIGER A COULTER KE BE N D E R SL SILVERSTEIN L DOCUMENT 1564 AUTHOR: DOW ADDRESSEE: COPYEE: 01/19/65 DOCUMENT 1565 AUTHOR: ADDRESSEE: COPYEE: 00/00/69 MEMO 1 LETTER 2 I DP LETTER WARD JC 2 LETTER 4 DOW DOW DOW STAEHLING EC CHART 29 MEMO 6 to CO TITLE PAGE 223 SUPPLEMENT TO PP 8F0670 24D SECTION C METABOLISM VOLUME 2 PETITIONS FOR THE ESTABLISHMENT OF TOLERANCES ON RAM AGRICULTURAL COMMODITIES FOR THE PESTICIDE CHEMICALS 245T (PP 8F0669) 24D CPP 8F0670) 2-C245-TRICHL0R0PHEN0XY) PROPIONIC ACID COMMON NAME SILVEX CPP 8F0675) 2-METHYL-4-CHL0R0PHEN0XYACETIC ACID CPP 8F0676). SUGGESTED AGENDA MEETING OF USDA, FDA AND NACA ON USE OF 24D AND 245T ON GRAZING LANDS (PESTICIDE PETITION 162). MEMORANDUM OF CONFERENCE USE OF 24D AND 245T ON GRAZING LAND (PESTICIDE PETITION 162). I EPS I FAV S U M M A R Y OF T O X I C I T Y F I G U R E S ON 2<t5T A N D I S O P R O P Y L P H E N O L CARBAMATE(IPC) CTTL. HISTORY OF CHLORACNE INCIDENCES AT DOM (CHLORACNE RESEARCH P R O G R A M K L A B REPORT NO. PL-2172-1). HABERSTROH MH SAUERS RC DOM HERBICIDES FISH TOXICITY IN EEK TABLES. THIRTY-EIGHT REFERENCES CITED CTTL NUMBER DATE DOCUMENT 1566 00/00/59 AUTHOR: RALPH MCELROY CO ADDRESSEE: COPYEE: DOCUMENT 1567 AUTHOR: DOH ADDRESSEE COPYEE: 02/12/65 DOCUMENT 1568 04/01/6A AUTHOR CLARK DE ADDRESSEE: COPYEE: DOCUMENT 1569 12/13/54 AUTHOR: DOW ADDRESSEE COPYEE: DOCUMENT 1570 AUTHOR: ADDRESSEE: COPYEE: 03/17/65 DOCUMENT 1571 04/21/65 AUTHOR ADDRESSEE COPYEE: BROWN MT DOW FALKENSTEIN HJ KAGY JF NORTON TR TYPE REPORT PAGES 17 REPORT OYEN F 1 REPORT HUNT LM 7 REPORT 9 MCCOLLISTER DD REPORT 95 DISTRB 2 REPORT DOW BARRONS KC G O R D O N HL KILIAN DJ PITMAN-MOORE =5ieA-(T, At to to O TITLE PAGE 224 THE CYTOSTATIC ACTION OF CERTAIN AUXINS PRELIMINARY REVIEW CPRESSE MEDICALE 67(6), 207-209, 590000). SUMMARY OF PATHOLOGY ON MALE AND FEMALE RATS FED K 39291 IN THE DIET FOR 18 MONTHS ( T 6 0 .14-39291-5). APPENDIX EIGHT TOXICOLOGIC EFFECTS OF SILVEX ON YEARLING CATTLE (JAVMA 144 (7), 7 50-75 5)(PROTOCOL 015 ABSORPTION OF SILVEX ESTERS THROUGH THE SKIN OF HUMAN VOLUNTEERS). PALMER JS APPENDIX SIX RESULTS OF RANGE FINDING TOXOLOGICAL TESTS ON M-213 (SILVEX AMINE FORMULATION)(PROTOCOL 015 ABSORPTION OF SILVEX ESTERS THROUGH THE SKIN OF HUMAN VOLUNTEERS). WOLF MA RESULTS OF TWO Y EAR DIETARY F EEDING S TUDY IN RATS OF KUROSAL SL ( P OTASSIUM SALT OF S I L V E X H A P P E N D I X 3). APPENDIX THREE, RESULTS OF TWO YEAR DIETARY FEEDING STUDY IN RATS OF KURASOL SL (POTASSIUM SALT OF SILVEX)(PROTOCOL 015 ABSORPTION OF SILVEX ESTERS THROUGH THE SKIN OF HUMAN VOLUNTEERS). MCCOLLISTER DD BOUNDY RH HAKE CL LYNN GE WILSON AW ELSHERE D JOHNSTON RV MULLISON HR NUMBER DOCUMENT 1572 DATE 01/18/66 AUTHOR: ADDRESSEE: COPYEE: DOCUMENT 1573 AUTHOR: DOM ADDRESSEE: COPYEE: 02/20/56 DOCUMENT 1574 AUTHOR: ADDRESSEE: COPYEE: ! DOCUMENT 1575 01/31/56 03/23/56 AUTHOR ADDRESSEE* COPYEE: DOM DOM BRITTON EC HART A MARTIN D DOCUMENT 1576 AUTHOR: DON ADDRESSEE C O P Y E E ' 04/03/61 DOCUMENT 1577 AUTHOR: DOM ADDRESSEE: COPYEE: 03/21/61 DOCUMENT 1578 AUTHOR: DOM ADDRESSEE: COPYEE: 07/04/61 TYPE REPORT PAGES 17 TEST LOCKMOOD D 4 TEST 1 DISTRB 7 TECH MCCOLLISTER DD ALL I N S O N RL ELSHERE D KILIA N DJ SUNDERLAND MM DATA TEST TOMPSON E 2 TEST OLSON KJ 2 TECH TOMPSON E 1 to to TITLE PAGE 225 APPENDIX ONE SOME TOXICOLOGICAL ASPECTS OF SILVEX (PRESENTED AT THE SOUTHERN HEED CONFERENCE 660118, JACKSONVILLE, FLHPROTOCOL 015 ABSORPTION OF SILVEX ESTERS THROUGH THE SKIN OF HUMAN VOLUNTEERS). ACETIC ACID. (245-TRICHL0R0PHEN0XY)- 6 -METHYL-HEPTYL ESTER (EYE CONTACT TEST). ACETIC ACID. (245-TRICHL0R0PHEN0XY)-, 6 -METHYL-HEPTYL ESTER (ACUTE ORAL TOXICITY). RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON ACETIC ACID (245 TRICHLOROPHENOXY)-, 6-METHYL-HEPTYL ESTER (FILE T25.14-302-1). OLSON KJ BESHGETOOR AW GAY HH LUCE EN WHITE LC BOUNDY RH GREENE LM MACCUTCHEON WRIGHT N DOWANOL PIB MIX ESTERS OF 245T (SKIN CONTACT - IRRITATION). DOWANOL PIB MIX ESTERS OF 245T (EYE CONTACT TEST). DOWANOL PIB MIX ESTER OF 245T (ACUTE ORAL TOXICITY). nnrijM EPT 70 r.v-..OR DOL. ADDRESSEE! COPYEE: 0* ' V 6 1 TEC" I OMPj u i i E DOCUMENT 1580 06/06/61 AUTHOR: TOMPSON E ADDRESSEE: COPYEE: TECH 1 DOCUMENT 1581 AUTHOR: DOW ADDRESSEE' COPYEE: 03/24/61 TECH TOMPSON E 1 DOCUMENT 1582 AUTHOR: ADDRESSEE: COPYEE- 06/12/61 TECH 2 DOCUMENT 1583 AUTHOR: ADDRESSEE' COPYEE: 09/28/61 TECH 1 DOCUMENT 1584 00/00/66 REPORT 4 AUTHOR ADDRESSEE: COPYEE: DARTMOUTH MEDICAL SMITH RP SCHOOL GLEASON MN UNIV OF ROCHESTER DOCUMENT 1585 00/00/61 AUTHOR: BOLLEN WB ADDRESSEE: COPYEE: REPORT OR ST UNIV 24 DOCUMENT 1586 AUTHOR: ADDRESSEE: COPYEE: 00/00/65 REPORT 133 O O ro jour' p i X E "'~i O F ")T ( *~"TE I--- T O ---- TYJ DOHANOL PIB MIX ESTER OF 2A5T (ACUTE ORAL TOXICITY). DOWANOL PIB MIX ESTERS OF 2Q5T (ACUTE ORAL TOXICITY). DOHANOL ESTER 245T (REQUEST FOR SCREENING OR APPLICATION TESTING) DOHANOL PIB MIX ESTER OF 2A5T (TOXICOLOGY HORK SHEET). 24D (CLINICAL TOXICOLOGY OF COMMERCIAL PRODUCTS)(ACUTE POISONING)(SECTION 3 THERAPEUTICS INDEX, 79-81). GOSSELIN RE HODGE HC INTERACTIONS BETHEEN PESTICIDES AND SOIL MICROORGANISMS (ANN. REV MICROBIOL. 15, 69-92). RESULTS OF TCDD EFFECT ON RABBIT EARS CTTL NUMBER DATE DOCUMENT 1587 12/00/67 AUTHOR: EDWARDS NT ADDRESSEE COPYEE: EDWARDS NT BELL F CORDEN M DAHLMAN RC EGLER F HOFFMAN G KAYE SV LARSON CE MORGAN KZ OLSON JS PATTEN BC REITEMEIER RF SHINN AF TANNER JT VANDYKE GM WOLFE JN TYPE PAGES REPORT 37 OAK RIDGE NATL LAB ANDREWS H BLAYLOCK BG CROSSLEY DA JR DAVIS JJ FRIBOURG H HOLTON RH KELLY JM LIVE R MA N JL NATL SCIENCE FOUND OPSTRUP PA PETERS LN RICH S SHOUP CS THOMAS WA WEINBERG AM DOCUMENT 1588 00/00/57 REPORT AUTHOR: PURDUE AG EXP LAFAYET ADDRESSEE: COPYEE ROBERTS RE 3 DOCUMENT 1589 AUTHOR: TINKER ADDRESSEE: COPYEE: 06/28/67 BP REPORT 12 DOCUMENT 1590 AUTHOR ADDRESSEE COPYEE 00/00/59 LEGAL 10 DOCUMENT 1591 03/22/66 REPORT AUTHOR ACTA VET SCAND STOCKHOLM ERNE K ADDRESSEE: COPYEE: 17 DOCUMENT 1592 09/00/67 REPORT A AUTHOR BIONETICS ADDRESSEE: COPYEE: FISHBEIN L to to CO TITLE PAGE 227 METABOLISM OF HERBICIDES IN ECOSYSTEMS. A REVIEW (ORNL-TM-2042). VANDYNE GM ATON FOREST CLEBSCH EE CT AG EXP DESELM HR GORE AJ HUNT G KITCHINGS JT MACPHERSON HG N E L S O N DJ OR ST UNIV REED JR RUTGERS UNIV STORY JD U.S. ATOMIC ENERGY COMM WITHERSPOON JP AUERBACH SI CO ST UNIV CURLIN JW DUNAWAY PB HABER AH JOSEPH A KOHAL NE MALONE CR NIERING W OSBURN W REICHLE DE SEATZ L STRUXNESS EG UNIV OF TN WITKAMP M T H E EF F E C T O F 2A5T B R U S H S P R A Y ON T U R K E Y S ( P O U L T R Y S C I E N C E 36, 703-705, 570000). ROGERS BJ TCDD. EXCERPTS FROM TESTIMONY REGARDING POSSIBLE PENTACHOLOPHENOL POISONING OF MI DAIRY HERDS C T T L . DISTRIBUTION A ND ELIMINATION OF C H L O R I N A T E D PHENOXYACETIC ACIDS IN A N I M A L S (ACTA VET S C A N D 7, 2 A 0 - 256). NATL VETEINARY INST SWED GAS CHROMATOGRAPHIC MEASUREMENT OF DISAPPEARANCE RATES OF 2AD AND 245T ACIDS AND 2AD ESTERS IN MICE (JOUR AG FOOD CHEM 15(5), 8A1-8A4). ZIELINSKI WLJR NUMBER DOCUMENT 1593 DATE 04/12/66 AUTHOR ERNE K ADDRESSEE COPYEE DOCUMENT 1594 AUTHOR ADDRESSEE COPYEE 00/00/61 DOCUMENT 1595 01/00/53 AUTHOR AMA ADDRESSEE COPYEE DOCUMENT 1596 AUTHOR ADDRESSEE COPYEE 03/22/67 DOCUMENT 1597 AUTHOR ADDRESSEE COPYEE 04/20/67 DOCUMENT 1598 07/06/64 AUTHOR BLEIBERG J ADDRESSEE COPYEE DOCUMENT 1599 04/25/67 AUTHOR DOM ADDRESSEE DOW COPYEE DOW SILVERSTEIN LG DOCUMENT 1600 06/04/69 AUTHOR DOW ADDRESSEE DOW COPYEE DOW ROWE VK to O TYPE PAGES NEWS 8 REPORT NATL VETERINARY IN REPORT 4 REPORT DRILL VA 8 REPORT 2 REPORT 2 REPORT BRODKIN RH 1 LETTER MIDIGER A COULTER KE BENDER SL STAEHLING EC 4 LETTER 2 SILVERSTEIN LG ASADORIAN AA DUNN FL SCHOBER AE TITLE PAGE 228 STUDIES ON THE ANIMAL METABOLISM OF PHENOXYACETIC HERBICIDES (ACTA V E T S C A N D 7, 264-271). ST SHE CHRONIC EFFECTS OF HERBICIDES. TOXICITY OF 24D AND 245T, A REPORT ON THEIR ACUTE AND CHLORIC TOXICITY IN DOGS (AMA ARCHIVES OF INDUS HYGIENE AND OCCUPATIONAL M E D I C I N E 7, 61-67). HIRATZKA T TCDD SINGLE DOSE ORAL TOXICITY TO RATS. TCDD SINGLE DOSE ORAL TOXICITY TO MALE GUINEA PIGS. PESTICIDES, CHLORACNE, AND PORPHYRIA CUTANEA TARDA. HILLARD JR CHLORACNE RESEARCH PROGRAM. HABERSTROH HH SAUERS RC TCDD, A POTENT ACNEGEN C T T L . LEAVITT FC SOLEM RH MILLS JF NUMBER DATE DOCUMENT 1601 11/00/61 AUTHOR: DOW ADDRESSEE-* COPYEE: DOW GREENE LM KILIAN DJ MCINTYRE HH WRIGHT N TYPE PAGES DATA 79 GREENHOE NC BOUNDY RH HART A LUCE EN PERKINS RP DOCUMENT 1602 AUTHOR: ADDRESSEE COPYEE: 00/00/69 REPORT 5 DOCUMENT 1603 04/09/62 AUTHOR: DOW ADDRESSEE* COPYEE* DOW C O U L T E R LL KAGY JF SWEZEY AW REPORT SEYMOUR KG BARRONS KC HANSON RG L I PP IE LJ WATSON AJ 26 DOCUMENT 1604 08/00/64 REPORT 4 AUTHOR: USDI ADDRESSEE: COPYEE DOCUMENT 1605 01/00/68 AUTHOR: COPE OB ADDRESSEE: COPYEE REPORT SANDERS HO 7 DOCUMENT 1606 04/00/66 AUTHOR: COPE OB ADDRESSEE COPYEE: REPORT SANDERS HO 6 i'c h - a : DOCUMENT 1607 04/00/64 AUTHOR: ADDRESSEE: COPYEE: AG EXP >& to to CH WOOSTER OH REPORT KING CC 5 TITLE PAGE 229 RESULTS OF 90 DAY DIETARY FEEDING STUDIES OF DOWANOL 97B ESTER 245T IN RATS. ELSHERE D JONES GD LYNN GE SHRADER SA GAY HH KAGY JF MARTIN D TISDALE ML SILVEX PESTICIDE DATA REPORT. CROSSLINKED POLY (POTASSIUM ACRYLATE) FOR SPRAY DRIFT CONTROL STATUS REPORT (TA-200). BROWN JH HARPER BG RITTY PM WILTSE MG COLBY RW JOHNSON JE SHIGLEY CM PESTICIDE WILDLIFE STUDIES, 630000. A REVIEW OF FISH AND WILDLIFE SERVICE INVESTIGATIONS DURING THE CALENDAR YEAR (FISH AND WILDLIFE SERVICE CIRCULAR 199). THE RELATIVE TOXICITIES OF SEVERAL PESTICIDES TO NAIADS OF THREE SPECIES OF STONEFLIES (LIMNOLOGY AND OCEANOGRAPHY 13(1), 112-117). SPORT FISHERIES AND WILD TOXICITIES OF SEVERAL PESTICIDES OF TWO SPECIES OF CLADOCERANS (TRANSACTIONS OF THE AM FISHERIES SOCIETY 95(2), 165-169). SPORT FISHERIES AND WILD EFFECTS OF HERBICIDES ON HONEYBEES (GLEANINGS IN BEE CULTURE 230-233). NUMBER DATE DOCUMENT 1608 01/10/57 AUTHOR: SPRINGER PF ADDRESSEE: COPYEE TYPE PAGES REPORT 11 US FISH AND MILDLIFE DOCUMENT 1609 01/22/60 AUTHOR: DREESSEN1 J ADDRESSEE: BUGH M COPYEE: LETTER 4 NACA IN ST HIGHMAY DEPT DOCUMENT 1610 00/00/61 AUTHOR: BAUER H ADDRESSEE: COPYEE: REPORT BERGMAN 27 DOCUMENT 1611 11/16/68 AUTHOR ADDRESSEE COPYEE: CAMPBELL AD HUANG A REPORT FIRESTONE D RESS J 2 DOCUMENT 1612 07/09/59 REPORT 18 AUTHOR: DOM ADDRESSEE COPYEE: DOM OYEN F BOUNDY RH DOCUMENT 1613 AUTHOR: DOM ADDRESSEE: COPYEE: 05/07/63 SPEC 1 DOCUMENT 1614 00/00/63 AUTHOR: DEMITT JB ADDRESSEE: COPYEE: REPORT MENZIE CM 5 -H 3 2 . 3 - DOCUMENT 1615 MAUTHOR: BUR OF w GEORGE ADDRESSEE: COPYEE: 00/00/60 REPORT SPORT FISHERIES A CRABTREE JL DG to to <T> 6 TITLE PAGE 230 EFFECTS OF HERBICIDES AND FUNGICIDES ON WILDLIFE CNC PESTICIDE MANUAL NC ST COL, 87-106). SER ALLEGED EFFECTS ON HUMANS WHEN EXPOSED TO 24D OR SIMILAR PRODUCTS CTTL. INDUSTRIAL POISONING IN THE MANUFACTURE OF CHLOROPHENOL COMPOUNDS (ARCHIV FR G E W E R B E P A T H O L O G I E UND G E W E RBEHYGIENE, 18, 538-555). SCHULZ KH SPIEGELBERG U CHEMICAL AND TOXICOLOGICAL EVALUATIONS OF ISOLATED AND SYNTHETIC CHLORO DERIVATIVES OF DIBENZO-P-DIOXIN (NATURE, 220, 702-703). HEW HIGGINBOTHAM GR VERRETT J R E S U L T S OF C O M P A R A T I V E S K I N T E S T S ON 1. E S T E R O N B R U S H K I L L E R OS 2. F O R R O N B R U S H K I L L E R 3. E S T E R O N 2 4 5 OS 4. F O R R O N 245 AT U S E CONCENTRATIONS. WOLF MA C O U L T E R LL VANVALKENBURG JW ESTERON 245 CONCENTRATE. EVALUATION OF CHEMICALS (TOXICITY TESTS ON BIRDS). SPANN JW VANCE C EFFECTS ON WILDLIFE DEWITT JB FINLEY RB NUMBER DATE TYPE DOCUMENT 1616 00/00/62 REPORT AUTHOR: BUR OF SPORT FISHERIES A COPE OB ADDRESSEE COPYEE: PAGES 2 DOCUMENT 1617 00/00/62 REPORT AUTHOR: DALGAARDMIKKELSEN S POULSON E ADDRESSEE: COPYEE: 26 DOCUMENT 1618 04/00/65 REPORT AUTHOR: CHESTERFORD PARK RES STA EDSON EF ADDRESSEE: COPYEE: 7 DOCUMENT 1619 AUTHOR: ADDRESSEE: COPYEE: 00/00/62 REPORT 2 DOCUMENT 1620 AUTHOR: DOW ADDRESSEE: COPYEE: 05/29/58 REPORT HYMAS TA 8 DOCUMENT 1621 03/05/65 LETTER 3 AUTHOR* ADDRESSEE COPYEE: DOW DOW DOW HOLDER BB SILVERSTEIN LG REPORT OHARE CP G ORDON HL OLSON KJ HOYLE HR STEWART RD DOCUMENT 1622 AUTHOR: DOW ADDRESSEE: DOW COPYEE: 03/29/65 LETTER 1 SILVERSTEIN LG ROWE VK DOCUMENT 1623 AUTHOR: ADDRESSEE: YEE: 07/23/65 CHART 1 r h '( z CO CO <1 TITLE SPORT FISHERY INVESTIGATIONS. PAGE 231 T O X I C O L O G Y OF H E R B I C I D E S ( P H A R M A C E U T I C A L R E V I E W 14, 225-250). ROYAL VETERINARY AND AG ACUTE TOXICITY DATA FOR PESTICIDES (640000) (WORLD REVIEW OF PEST CONTROL 4(1), 36-41). NOAKES DN SANDERSON DM THE TOXICITY TO FISH OF DIFFERENT FORMULATIONS OF 245T, 2124-DP) AND SILVEX (PROC SO WEED CONF, 265-266). TOXICITY OF HERBICIDES TO DOMESTIC ANIMALS. THE INEFFECTIVENESS OF WASHING AS A PREVENTIVE MEASURE IN THE FORMATION OF FOLLICULITIS IN THE RABBIT EAR FOLLOWING REPEATED APPLICATIONS OF SYMMETRICAL TETRACHLORODIBENZO-DIOXIN. OLSON KJ ADAMS EM KRAMER CG GAY HH ROWE VK RESULTS OF THE RABBIT EAR TEST USING PURE SYMMETRICAL TETRCHLOROBENZODIOXIN CTTL. WIPE TESTS ON RENTED SPARKLER FILTERS 199 BUILDING. . UMfl. DOCUMENT 1624 AUTHOR: DON ADDRESSEE COPYEE: ---- : 04/02/54 DOCUMENT 1625 07/09/59 AUTHOR: ADDRESSEE: COPYEE: DON WOLF MA DOW DOCUMENT 1626 AUTHOR: DOW ADDRESSEE: DOW COPYEE: 05/21/58 DOCUMENT 1627 00/00/67 AUTHOR: BLACK WD ADDRESSEE: COPYEE DOCUMENT 1628 AUTHOR: DRILL ADDRESSEE COPYEE*- 00/00/47 VA DOCUMENT 1629 00/ 00/66 AUTHOR: BJORKLUND NE ADDRESSEE COPYEE DOCUMENT 1630 02/00/50 AUTHOR: FARWELL ED ADDRESSEE: COPYEE: DOCUMENT 1631 01/00/53 AUTHOR: DRILL VA ADDRESSEE: COPYEE: y 5 to p to oo . . E .-JS DATA 238 MCCOLLISTER DD REPORT MOORE V 5 BOUNDY RH REPORT 3 MCCOLLISTER DD C O U L T E R LL REPORT CRAWFORD LM 3 REPORT HIRATZKA T 15 REPORT ERNE K 14 REPORT GRIGSBY BH 8 REPORT HIRATZKA T 8 TI',.. p2 SILVEX SODIUM SALT 90-DAY DIET-RAT (K-8690-(1))CT60.19-39-1). RESULTS OF COMPARATIVE SKIN TESTS ON ESTERON BRUSH KILLER OS PORRON BRUSH KILLER ESTERON 295 OS FORRON 295. OYEN F RONE VK C O U L T E R LL VANVALKENBURO JW RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON WEED KILLER FORMULATION M-1099 CONTAINING A 295T ESTER. OLSON KJ HERBICIDE TOXICITY TO DOMESTIC ANIMALS (362-369). UNIV OF GA ACUTE AND CHRONIC TOXICITY OF 29D AND 295T IN DOGS. NAYNE UNIV COL TOXICOLOGICAL STUDIES OF PHENOXACETIC HERBICIDES IN ANIMALS (AETA VET SCAND 660000 369-390). NATL VETERINARY INST STO ROYAL VETERINARY COL SOME EFFECTS OF HERBICIDES ON PASTURE AND ON GRAZING LIVESTOCK (MICHIGAN QUATERLY BULLETIN 32 (3) 378-385). TOXICITY OF 29D AND 295T. A REPORT ON THEIR ACUTE AND CHRONIC TOXICITY IN DOGS (AMA ARCHIVES OF INDUSTRIAL HYGIENE AND O C C U P A T I O N A L M E D I C I N E 7, 61-67). NUMBER DATE DOCUMENT 1632 00/00/63 AUTHORi HAYES WJ ADDRESSEE COPYEE DOCUMENT 1633 AUTHOR DOW ADDRESSEE DOW COPYEE 10/21/52 DOCUMENT 1634 02/27/59 AUTHOR: DOW ADDRESSEE KLAUDER JV COPYEE DOCUMENT 1635 01/02/59 AUTHOR: DOW ADDRESSEE: COPYEE: DOW COLBY RW GRAY HE HYMAS TA LUCE EN STENGER VA DOCUMENT 1636 06/22/61 AUTHOR KLAUDER JV ADDRESSEE DOW COPYEE: DOCUMENT 1637 AUTHOR: DOW ADDRESSEE COPYEE: 00/00/69 DOCUMENT 1638 AUTHOR: DOW ADDRESSEE DOW COPYEE: DOW JOHNSON 03/05/62 JE TYPE REPORT HEW PAGES 5 LETTER ROWE VK BRITTON JW 1 LETTER ROWE VK 1 REPORT ROWE VK WHITE LC C O U L T E R LL GREENE LM JONES GD LYNN GE T ISDALE WL LETTER ROWE VK 2 2 REPORT KENAGA EE 5 LETTER LYNN GE MCCOLLISTER BARRONS KC KAGY JF 1 DD 7lCu * t\> \ t o co ' TITLE CLINICAL HANDBOOK ON ECONOMIC POISONS TREATING POISONING. PAGE 233 EMERGENCY INFORMATION FOR ACUTE AND CHRONIC TOXICITY OF 24D AND 245T IN DOGS. SMITH HL WILLIAMS GJ KURON. KURON (REQUEST FOR SCREENING OR APPLICATION TESTING) (LOT 500458). WHITE LC BARRONS KC ELSHERE D HAMMER OH KAGY JF MCINTYRE HH WRIGHT N BOUNDY RH GAY HH HART A KILIAN DJ PERKINS RP A COMPILATION OF INFORMATION ON THE TOXICOLOGY OF SILVEX (REPEATED INSULT PATCH TEST WITH 1 PER CENT AQUEOUS SOLUTION KUROSAL. SL). TORDON HERBICIDES EVALUATION OF SAFETY TO FISH AND BIRDS (DTE 25, 5-9). DIETARY FEEDING STUDY IN RATS AND DOGS C T T L . COLBY RW RITTY PM COUL T E R LL NUMBER DOCUMENT 1639 AUTHOR DOM ADDRESSEE DOM COPYEE DOM DATE 02/19/63 TYPE PAGES LETTER HAMMER OH WIFFEN EE LYNN GE 1 DOCUMENT 1690 10/29/67 AUTHOR OLSON KJ ADDRESSEE PROCTER AND GAMBLE COPYEE LETTER SNYDER FH 2 DOCUMENT 1691 02/22/60 AUTHOR ADDRESSEE C O P YE E DOM DOM COLBY RN HAMMER OH KAGY JF MCINTYRE HH WRIGHT N REPORT JOSEPHS MJ JOSEPHS MJ ELSHERE D HART A K I L I A N DJ PERKINS RP 18 DOCUMENT 1692 AUTHOR I HCS ADDRESSEE COPYEE 08/20/59 CHART 7 DOCUMENT 1693 AUTHOR DOM ADDRESSEE DOM COPYEE DOM 09/26/60 LETTER JOSEPHS MI ROME VK FALSEY M 1 DOCUMENT 1699 05/02/60 AUTHOR DOM ADDRESSEE DOM COPYEE DOM VANVALKENBURG JM LETTER LYNN GE JOSEPHS MJ HYMAS VK 3 DOCUMENT 1695 09/19/61 AUTHOR COPELAND JR ADDRESSEE COPYEE DOM EPSTEIN J KAGY JF y PITMAN MOORE S LETTER DOM 2 LYNN GE FALKENSTEIN K I L I A N DJ WHITE L WJ TITLE CHRONIC TOXICITY OF SILVEX TO LABORATORY RATS. PAGE 23A MCCOLLISTER DO DESCRIBES DON'S USE OF BIOASSAY ON RABBITS' EARS TO DETERMINE ACNEGENS CTTL. RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON AGRICULTURAL CHEMICAL FORMULATION M1500 (SOLUTION OF SODIUM SALT OF SILVEX) OLSON K OYEN F BARRONS KC GAY HH HYMAS TA LUCE EN STENGER VA BOUNDY RH GREENE LM JONES GD LYNN GE TISDALE ML (2-(245-TRICHL0R0PHEN0XY) PROPIONATE) (SILVEX ESTER). PLANS TO DROP M-1500 FOR M-1845. LYNN GE RITTY PM POTASSIUM SALT OF SILVEX. RITTY PM ROWE VK KURSAL SL (POTASSIUM SALT OF SILVEX). LYNN GE BOUNDY RH G O R D O N HL MULLISON NR WILSON AW COLBY RW HAKE CL NORTON TR NUMBER DATE DOCUMENT 1646 12/13/54 AUTHOR! ADDRESSEE: COPYEE: DOW DOW BARRONS KC COLBY RW KAGY JF MACCUTCHEON SM TYPE PAGES REPORT 10 MCCOLLISTER DD ALLINSON RL BESHGETOR AW DAVIDSON JH KELLY JA SUNDERLAND WW DOCUMENT 1647 09/20/51 AUTHOR: ADDRESSEE! COPYEE: ADAMS DOW BRITTON JW HEATH SB NELSON WL REPORT 32 DOW BERHENKE LF DAVIDSON JH HIRSCHKIND W RECHTIN HJ DOCUMENT 1648 AUTHOR: ADDRESSEE: COPYEE: DOCUMENT 1649 00/00/51 MEMO 07/20/62 LETTER 1 2 AUTHOR! DOW ADDRESSEE: DOW COPYEE: DOW ROWE VK WIFFEN EE C O U LT ER LL DOCUMENT 1650 AUTHOR: ADDRESSEE: COPYEE: 00/00/69 REPORT 18 DOCUMENT 1651 AUTHOR: ADDRESSEE: COPYEE: 09/12/66 REPORT DOCUMENT 1652 00/00/66 REPORT AUTHOR: NY ST EXP STATION AT GEN ADDRESSEE: COPYEE: 9 5 & TO 5U C O TITLE PAGE 235 RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON M-213 CSILVEX AMINE FORMULATION). HOLF MA ALQUIST FN BOUNDY RH GAY HH LUCE EN WRIGHT N BACON KD BRITTON EC GREENE LM LYNN GE WRIGHT P RESULTS OF TOXICOLOGICAL TESTS ON ALPHA 245 TRICHLOROPHENOXY PROPIONIC ACID. RONE VK BRANCH CB DUTTON WC KELLY JA SOUTHWICK L BRITTON EC HAMMER OH LYNN GE SILVEX. A COMPILATION OF INFORMATION ON THE TOXICOLOGY OF SILVEX (LETTER FROM VK ROHE TO EE HIFFEN DOW SUMMARIZING TOXICOLOGICAL INFORMATION ON KUROSAL SL AND KUROSAL G INCLUDING WORK ON HUMANS). LYNN GE ANALYSIS OF LABORATORY FINDINGS AND HEALTH HISTORY RESPONSES AMONG MEN EXPOSED TO 245T. PHENOXY HERBICIDES IN PASTURE RANGELAND OR ALONG ROADSIDE AND 24D RESIDUES IN MILK C T T L . PHENOXY HERBICIDES IN PASTURE AND RANGELAND OR ALONG ROADSIDE. NUMBER DATE DOCUMENT 1653 01/20/60 AUTHORi GOLDSTEIN HE ADDRESSEE: COPYEE: DOCUMENT 1654 AUTHOR: USDI ADDRESSEE: COPYEE: 09/30/66 DOCUMENT 1655 AUTHOR: USDI ADDRESSEE: COPYEE: 00/00/65 DOCUMENT 1656 09/07/60 AUTHOR: ADDRESSEE: COPYEE: DOW DOM DOH F A L S E Y 1WP LEASURE JK ROWE VK DOCUMENT 1657 03/17/55 AUTHOR: ADDRESSEE: COPYEE: DOW DOW BESHGETOOR GAY HH LYNN GE WRIGHT P AW DOCUMENT 1658 08/30/50 AUTHOR: ADDRESSEE* COPYEE: DOW WAYNE DOW UNIV DOCUMENT 1659 AUTHOR: DOW ADDRESSEE: \COPYEE : 00/00/49 TYPE PRESENT LONG JF PAGES 9 REPORT 5 REPORT 25 REPORT 3 WINSTON AW JR JOSEPH MJ BARRONS KC G ANTZ RL LIPPIE LJ TRUCHELUT GB REPORT 5 MCCOLLISTER DD A L L I N S O N RL BOUNDY RH GREENE LM MACCUTCHEON SM REPORT DRILL VA 1 BRITTON JW REPORT 4 MCCOLLISTER DD $ ro OJ to TITLE PAGE 236 OBSERVATIONS ON CATTLE SHEEP AND SWINE EXPOSED TO 24D 245T AND DALAPON HERBICIDES (PROC SWCC 13(5), 1-9) C T T L . OH DEPT OF AG SPORT FISHERY RESEARCH (QUARTERLY PROGRESS REPORTS). PROGRESS IN SPORT FISHERY RESEARCH, 650000. RESULTS OF FISH TOXICITY AND TASTE EXPERIMENTS ON TWO POTASSIUM SALT OF SILVEX FORMULATIONS. C O U L T E R LL HAMMER OH LYNN GE VANVALKENBURG JW DOSSER RC JOHNSON JE RITTY PM RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON PENTAERYTHRITOL TETRAKIS, 2-(245-TRICHL0R0PHEN0XY)PR0PI0NATE (CRI 125192). OYEN F ALQUIST FN BRITTON EC KAGY JF SUNDERLAND WW BACON KD COLBY RW LUCE EN WRIGHT N INTERIM REPORT ON THE ACUTE AND SUBACUTE ORAL TOXICITY OF 245T FOR DOGS. ROWE VK SPENCER HC THE ACUTE ORAL TOXICITY OF 245T TO RATS, MICE, GUINEA PIGS AND CHICKS. ROWE VK SPENCER HC NUMBER DATE DOCUMENT 1660 12/00/54 AUTHOR DOBSON N ADDRESSEE * COPYEE: TYPE REPORT PAGES 4 DOCUMENT 1661 10/09/56 AUTHOR: DAVIDSON JH ADDRESSEE: COPYEE: DOW SMITH H REPORT DOW BECKWITH C 4 DOCUMENT 1662 11/13/68 AUTHOR: DOW ADDRESSEE: COPYEE: DOW DIETER CE KAGY JF PERKINS RP WARREN LE REPORT WATSON AJ BARRONS KC HAMMER OH IIP P I E LJ SPALDING J 15 DOCUMENT 1663 09/10/58 REPORT AUTHOR: ADDRESSEE: COPYEE: AL P O L Y T E C H N I C I N S T I T U T E D O W LIPPIE LJ WATSON AJ DOW COLBY RW JOHNSON JE NUTTING HS VANVALKENDURG JW BARRONS KC DIETER CE KAGY JF PERKINS RP WARREN LE 42 DOCUMENT 1664 02/15/60 AUTHOR: ADDRESSEE: COPYEE: DOW DOW HAMMER OH JOSEPHS ME NORTON TR VANVALKENBURG JW ABSTRACT STEVENSON GT BARRONS KC HINMAN CN KAGY JF PERKINS RP 1 ro CO CO TITLE PAGE CHEMICAL SPRAYS AND POULTRY (THE JOURNAL OF THE MINISTRY OF AGRICULTURE 61(9), 415-418). 237 15TH ANNUAL OH HIGHWAY SHORT COURSE (ROI 12355). COON ET MCCOMB JH A FIELD EVALUATION OF SEVERAL EXPERIMENTAL AQUATIC HERBICIDES SUPPLEMENT TO SH REPORT 391 (SH 393) (206567). BLAIR EH HANSON RG LYNN GE SWEZEY AW COLBY RW JOHNSON JE NORTON TR VANVALKENBURG A FIELD EVALUATION OF SEVERAL EXPERIMENTAL AQUATIC HERBICIDES (SH REPORT 391)(206565). HAMMER OH LAWRENCE JM BLAIR EH HANSON RG LYNN GE SPALDING J BOUNDY RH HINMAN CW NORTON TR SWEZEY AW SILVEX ADDED TO THE DRINKING WATER OF CATTLE, SHEEP, SWINE, TURKEYS, DUCKS AND CHICKENS (GH 480)(144818). BLAIR EH HYMAS TA L I P P I E LJ RAPER JT COLBY RW JOHNSON JE LYNN GE SPALDING J NUMBER DATE DOCUMENT 1665 12/27/68 AUTHOR: ADDRESSEE! COPYEE: BARRONS KC GRIFFIN JD I EHB I CWH DOCUMENT 1666 11/09/65 AUTHOR! ADDRESSEE! COPYEE! DOW DOW G ORDON HL KAGY JF MULLISON WR DOCUMENT 1667 AUTHOR: ADDRESSEE* COPYEE! 02/11/59 DOCUMENT 1668 02/00/50 AUTHOR! FARWELL ED ADDRESSEE: COPYEE: DOCUMENT 1669 AUTHOR: DOW ADDRESSEE! COPYEE: 05/17/60 DOCUMENT 1670 AUTHOR: DOW ADDRESSEE*. COPYEE! DOW 05/01/61 DOCUMENT 1671 AUTHOR DOW ADDRESSEE: COPYEE: 02/00/52 TYPE PAGES REPORT 15 BLAIR EH I CWH HENMAN CW DOW REPORT O'HARE CP BARRONS KC GOWELL JH KIL I A N DJ WILSON AW REPORT 8 5 REPORT GRIGBY BH 5 REPORT NORRIS MG 1 REPORT NATION HA WALKER REPORT ROWE VK 2 6 TITLE PAGE 238 WHAT ARE THE ECOLOGICAL BENEFITS OF HERBICIDES CONTROL? (B-14281 H118076). DAVIS H DOW I JLS I JS GRIFFEN JD BLAIR EH FOR WOODY PLANT SKIN IRRITATION AND ACNEGENIC PROPERTIES OF VEON BRUSH KILLER, VEON 245T, TORDON 101 AND WEEDAR 245T AMINE. OLSON KJ OVEN F BOUNDY RH JOHNSTON RV LYNN GE WILTSE MG ELSHERE D JONES GD MOSS RD TOXICITY TO FISH (ROI 30731). SOME EFFECTS OF HERBICIDES ON PA S T U R E AND ON GR A Z I N G LIVESTOCK (MI AG EXP STATION QUARTERLY BULLETIN 32(3), 3 7 8 - 3 8 5 K R 0 I 30712). PRELIMINARY RESULTS OF TOXICOLOGY TESTS WITH HERBICIDE FORMULATIONS (ROI 43531). NORRIS MG JR I FISH TOXICITY OF SEVERAL CHEMICAL FORMULATIONS (ROI 41626). HEALTH HAZARDS ASSOCIATED WITH HANDLING AND USE OF HERBICIDES (AGRICULTURAL CHEMICALS) (NE WEED CONTROL CONFERENCE NY CITY) NUMBER DATE TYPE PAGES DOCUMENT 1672 00/00/65 REPORT 5 AUTHOR.- BUR OF C O M M F I S H E R I E S FL B U T L E R PA ADDRESSEE COPYEE: DOCUMENT 1673 00/00/63 REPORT AUTHOR CA INST OF TECHNOLOGY ADDRESSEE COPYEE MCKEE JE 3 DOCUMENT 1674 AUTHOR ADDRESSEE COPYEE 02/27/69 REPORT 8 DOCUMENT 1675 AUTHOR DOW ADDRESSEE DOM COPYEE 03/21/69 MEMO 1 LENG ML GETZENDANER ME DOCUMENT 1676 AUTHOR DOM ADDRESSEE COPYEE 03/27/69 REPORT LENG ML 4 DOCUMENT 1677 00/00/69 AUTHOR RODGERS C ADDRESSEE COPYEE REPORT STALLING 9 DOCUMENT 1678 AUTHOR DON ADDRESSEE DOM , COPYEE 03/13/69 LETTER 1 KENAGA EE MCCOLLISTER DD ieeh-(Ti DOCUMENT 1679 11/11/59 AUTHOR: HAERTL EJ ADDRESSEE COPYEE: HAERTL EJ BIRON RA C O L L I E R BL FOSTER T HAMMER OH JOHNSTON H LYNN GE ^ NUTTING HS ca or REPORT 17 ALLEN MM BOUNDY RH DOM GETZENDANER HANSON RG JOSEPHS M MARTIN D O H S CE ME TITLE PAGE 239 EFFECTS OF HERBICIDES ON ESTUARINE FAUNA (SOUTHERN WEED CONTROL C O N F E R E N C E P R O C E E D I N G S 18, 576-80. WATER QUALITY CRITERIA (CA STATE WATER QUALITY CONTROL BOARD P U B L I C A T I O N 3 - A ). PUB HEALTH SERV WOLF HW METABOLISM, ABSORPTION, AND EXCRETION OF 2A5T IN SHEEP C T T L . REQUEST FOR DATA AND INFORMATION ON RESIDUES OF 2AD IN MEAT CTTL. 24D RESIDUES IN SHEEP TISSUE (GHP551). ANNUAL PROGRESS REPORT 690000. FISH-PE S T I C I D E RES LAB COLUMBIA MO. R I C H A R D A. SCHOETTGER, DIRECTOR. R8D HIGHLIGHTS. VERSENE AND VERSENOL IN FERTILIZERS (ROI 21291). BARRONS KC BRITTON FALSEY W GIBSON JW IRVINE MB JW MULLISON WR PEARSE FS BENDALL TL COLBY RW FISHER JR GULL1KSON G JOHNSON JE KAGY JF NATION HA RAYNOR RN NUMBER DATE RITTY PM SWEZEY AM WATSON AJ DOCUMENT 1680 06/09/52 AUTHOR: BARRONS KC ADDRESSEE: COPYEE: DOCUMENT 1681 08/18/55 AUTHOR: DOW ADDRESSEE: GARMHAUSEN WG COPYEE: DOW JOHNSON JE DOCUMENT 1682 05/21/57 AUTHOR: C O U L T E R LL ADDRESSEE: COPYEE: DOW BRYANT CA DAVIDSON JH FOSTER T KELLY JA MULLISON WR RAYNOR RN SHELDON HW WARDEN RL DOCUMENT 1683 01/10/57 AUTHOR: C O U L T E R LL ADDRESSEE: COPYEE: C O U L T E R LL BENDALL TL BROWER HH COON ET GIBSON JW LEASURE JK PAGE TJ RICHARDS WF SEEKER B WATSON AJ TYPE PAGES RONE VK VANHORN JC WILSON JW REPORT DOM 6 LETTER 2 REPORT ROME VK ST OF OH DEPT BARRONS KC KARLEVETZ F OF REPORT DOW ALLEN WW COLBY RW FALSEY WP GIBSON JW LEASURE JK NATION HA RITTY PM SMITH GN WARREN LE 11 REPORT 12 DOW DOW BLAIR EH BRYANT CA DAVIDSON JH GULLIKSON GE MULLISON WR PEARSE FS RITTY PM SMITH HL WILTSE MG we/,-r to CO 02 TITLE SHIGLEY CM VANVALKENBURG N WILTSE MG SPALDING JL HARDEN RL PAGE 240 HILDLIFE AND HEEDKILLERS (OUTDOOR HRITERS ASSN OF AMERICA AT MIAMI, FL ON 5 2 0 6 0 9 H R O I 13573). CALVES THOUGHT TO HAVE DIED FROM 24D POISONING FOUND TO HAVE DIED FROM LEAD SPRAYED IN THE PASTURE (ROI 9915) C T T L . HIGHNAY CHEMI TROL NORTON TR HYMAS TA S M I T H HL "HHAT ABOUT KURON!" (ROI 12850). BENDALL TL C O N N O R DL FAYERHEATHER GREEN J LYNN GE PEARSE FS ROHE VK S M I T H HL HATSON AJ BL BRITTON JH COON ET FISHER JR GULLIKSON GE MADDOX JF PRESCOTT RF SEEKER B SOUTHWICK L HILTSE MG ACD PROJECT STATUS REPORT HILDLIFE HABITAT MANAGEMENT AND DOH HERBICIDES (ROI 12611). ALLEN HH BRITTON EC COLBY RH FISHER JR JOHNSON JE NATION HA PRESCOTT RF RONE VK HARDEN RL ASHUORTH RH BRITTON JH C OLLIER BL FOSTER T KELLY JA NUTTING HH RAYNOR RN SANFORD DH HARREN LE NUMBER DATE DOCUMENT 1684 0 2 /0 0 /5 0 AUTHOR: FARWELL ED ADDRESSEE: COPYEE: DOCUMENT 1685 AUTHOR: DOM ADDRESSEE' COPYEE: 00/00/68 DOCUMENT 1686 AUTHOR: DOM ADDRESSEE COPYEE: 05/24/60 DOCUMENT 1687 AUTHOR: DOM ADDRESSEE DOM COPYEE DOM 05/25/60 DOCUMENT 1688 05/11/60 AUTHOR: COULTER LL JOHNSON JE ADDRESSEE DOM COPYEE: ONDRUS M DOCUMENT 1689 02/26/65 AUTHOR: GROTH DH ADDRESSEE: THOMPSON -HAYWRD COPYEE: DEATLEY LS DOCUMENT 1690 03/24/67 AUTHOR: DOD BDSA ADDRESSEE: DOM COPYEE: DOCUMENT 1691 00/00/57 AUTHOR: HAMBURG- EPPENDO ADDRESSEE: COPYEE: SCHULZ KH y 4 to CO U) vw <1 TYPE PAGES REPORT 8 GRIGSBY BH REPORT KENAGA EE 5 REPORT JOSEPHS MJ 14 LETTER HOLF MA RITTY PM COULTER LL 2 REPORT DAVIS H MONROE E RITTY PM PLUMMER DM 13 LETTER 1 HEM PATHOLOGY UPTON ET GILL H LETTER ZEPP MJ HICKMAN RA 1 REPORT KIMMIG J 5 TITLE PAGE 241 SOME EFFECTS OF HERBICIDES ON PASTURE AND ON GRAZING LIVESTOCK (MI AG EXP STATION QUARTERLY BULLETIN 32(3), 378-385). MI ST UNIV TORDON HERBICIDES-EVALUATION OF SAFETY TO FISH AND BIRDS. POTASSASIUM SALT OF SILVEX FOR AQUATIC HEED CONTROL (GH-498)(144836). COMMENTS ON BULLETIN ENTITLED 'AQUATIC VEGETATION CONTROL WITH KURON' BY MARK G HILTSE (110141). HILTSE MG AQUATIC VEGETATION CONTROL WITH KURON (110141). DOH I TM HILTSE MG WOLF MA UPDATE ON TECHNIQUE INFORMATION CTTL. ROHE VK ACCELERATED DELIVERY OF ORANGE CTTL. OCCUPATIONAL CHLORACNE CAUSED BY AROMATIC CYCLIC ETHERS (DERMATOLOGICA, 115 (1957) 540-546). NUMBER DOCUMENT 1692 DATE 11/30/69 AUTHOR: DOM ADDRESSEE: COPYEE * DOCUMENT 1693 AUTHOR: DOM ADDRESSEE: COPYEE: 00/00/69 r DOCUMENT 1699 03/26/65 AUTHOR: DOM ADDRESSEE: DOM COPYEE: ADAMS EM KRAMER CG SILVERSTEIN LG DOCUMENT 1695 03/20/67 AUTHOR: DOM ADDRESSEE: COPYEE: DIXON HR PLETCHER DE DOCUMENT 1696 05/29/67 AUTHOR: DOM ADDRESSEE: DOM COPYEE: BEUTEL AP EVERSON JM MILLS KA SMITH A DOCUMENT 1697 09/25/67 AUTHOR: DOM ADDRESSEE: DOM COPYEE: BEUTEL AP EVERSON JM MILLS KA SMITH LR TYPE TEST PAGES 6 REPORT 3 LETTER 3 OHARE CP GORDON HL GAY HH OLSON KJ STEHART RD ROC 3 HICKMAN RA GOMELL JH SUNDERLAND MM REPORT HICKMAN RA BALLMAN DK COFFEY HH GUNN FJ PATTERSON RM MILLIAMS GJ 3 REPORT HICKMAN DK BALLMAN DK COFFEY MH GUNN FJ PATTERSON RM MILLIAMS GJ 3 ro CO -t 00 TITLE PAGE 242 THE DETERMINATION OF COMPOUNDS CAPABLE OF CAUSING CHLORACNE IN 2,4,5-TRICHLOROPHENOL PROCESS SAMPLES BY GAS-LIQUID CHROMATOGRAPHY (MLW.64.19 ). CHRONOLOGY OF CHLORACNE TESTING IN BRL. THE INEFFECTIVENESS OF WASHING AS A PREVENTIVE MEASURE IN THE FORMATION OF FOLLICULITIS IN THE RABBIT EAR FOLLOWING REPEATED APPLICATIONS OF TCDD IN CORN OIL. HOLDER BB ROWE VK HOYLE HR SADEK SE REPORT OF CALL BETWEEN THE GOVERNMENT AND DOW DISCUSSING DOWS CAPACITY AND POSSIBLE EXPANSION OF FACILITIES TO PRODUCE HERBICIDES FOR GOVERNMENT USE CTTL. HANSON KY YANKA DE KEIL RM MONTHLY REPORT FOR MAY, 1967. CRAWFORD RF HUGHES CB ROBERTSON CD YANKA DE DOUGLAS B KNAUP LR RYAN WJ MONTHLY REPORT FOR APRIL, 1967. CRAWFORD RF HUGHES CB ROBERTSON CD YANKA DE DOUGLAS B KNAUP LR RYAN WJ NUMBER DATE DOCUMENT 1698 11/20/67 AUTHOR) DOM ADDRESSEE) DON COPYEE) BEUTEL AP EVERSON JH PATTERSON RM RYAN HJ DOCUMENT 1699 AUTHOR) DOH ADDRESSEE) COPYEE) 07/07/65 DOCUMENT 1700 03/30/67 AUTHOR) MARRONE S ADDRESSEE) COPYEE: BARRONS K LEDLIE RB . MULL ISON HR YANKA D DOCUMENT 1701 0A/20/67 AUTHOR) DOH ADDRESSEE: COPYEE) HANES JH LEDLIE RB MULLISON HR HRIGHT RH DOCUMENT 1702 00/00/63 AUTHOR: DOH ADDRESSEE) COPYEE) COHEN S DOCUMENT 1703 08/30/67 AUTHOR) DON ADDRESSEE) DOH COPYEE: BEUTEL AP EVERSON JH PATTERSON RM SMITH A TYPE PAGES REPORT HICKMAN RA BALLMAN DK COFFEY WH FOSTER PS QUIGLEY FK SMITH A 2 TEST A CONTRACT 75 US ARMY BIO LAB BOUNDY RH MAASBERG AT PLETCHER DE CONTRACT 1 HANES JH BARRONS K MAASBERG AT PLETCHER DE YANKA D CHART 3 LYNN GE REPORT HICKMAN RA BALLMAN DK COFFEY HH GUNN FJ ROADS DC HILLIAMS GJ 2 fO CO IN CD \ TITLE MONTHLY REPORT FOR NOVEMBER 1967 PAGE 2A3 CRANFORD RF GUNN FJ ROADS DC YANKA DE DOUGLAS B KNAUP LR ROBERTSON CD ANALYTICAL METHOD THE DETERMINATION OF TCDD IN TRICHLOROPHENOL (GAS CHROMATOGRAPHIC METHOD) (MLW 65.10). CONTRACT DAAA13-67-C-0137 NEGOTIATED CONTRACT APRIL 13, 1967. DIXON W MATHEHS C SCHAMBRA NS HANES JH MORRISON IG NRIGHT RN RESEARCH AGREEMENT NO. DAAAA13-67-C-0137 ON FORMULATION AND TESTING FOR BIOLOGICAL ACTIVITY, A GROUP OF SOLUABLE DNBP COMPOSITIONS. DIXON N MATHENS C ROTH HL HANMER AP MORRISON IG SCHAMBRA NS SUMMARY OF ACUTE ORAL TESTS (BY INTUBATION) ON 24D AND 245T AND A NUMBER OF THEIR DERIVATIVES. MCNAMARA B NOLF MA MONTHLY REPORT FOR AUGUST 1967. CRANFORD RF HUGHES CB ROBERTSON CD YANKA DE DOUGLAD B KNAUP LR RYAN NJ '"''UMr"'- r' " *1/6" uiHOfc- DOm ADDRESSEE' DOM COPYEE : BEUTEL AP EVERSON JW PATTERSON RM SMITH A DOCUMENT 1705 07/19/66 AUTHOR i NAVL PUBLICATI ADDRESSEE' COPYEEi LAPOINTE LD DOCUMENT 1706 04/19/63 AUTHOR' DOM ADDRESSEE' COPYEE' COHEN S DOCUMENT 1707 09/15/65 AUTHOR' BARRONS KC ADDRESSEE' COPYEE' DDC DOCUMENT 1708 12/27/67 AUTHOR' DOM ADDRESSEE DOM COPYEE' DEUTEL AP EVERSON JM PATTERSON RM RYAN MJ DOCUMENT 1709 10/11/65 AUTHOR' ADDRESSEE' ABELES FB DOM FRANK JR HURTT W LEE MM MON RIDDELL JA UNIV OF CA WILCOX R HICKMAN RA BALLMAN DK COFFEY MH GUNN FS ROADS DC WILLIAMS GJ Al RI T F ULY .7. CRAWFORD RF HUGHES CB ROBERTSON CD YANKA DE DOUGLAS B KNAUP LR RYAN MJ SPEC US ARMY 7 MILITARY SPECIFICATION. HERBICIDE) N-BUTYL 245-TRICHl.OROPHENOXYACETATE (MIL-H-51148A(MU) 661107). AMENASSN OF OFFICIAL AG CHEMISTS; AM SOCIETY FOR TESTING & MATERIALS) US PHARMACOPEIAL CONVENTION)MACK PUBLISHING) UNIFORM CLASSIFICATION COMM;US GOVT PRINTING OFF) NAVAL PUBLICATIONS & FORMS CENTER)LAPOINTE LD;DOM NAVAL PUBLICATIONS AND F CHART 3 SUMMARY OF ACUTE ORAL TESTS (BY INTUBATION) ON 24D AND 245T AND A NUMBER OF THEIR DERIVATIVES. LYNN GE MCNAMARA B WOLF MA REPORT DOM 40 FINAL CONTRACT REPORT COVERING THE PERIOD FROM MARCH 1964 TO 15 SEPTEMBER 1965 (CONTRACT NO. DA 18-064-AMC-222(A)). U.S. ARMY BIO LABS MD REPORT HICKMAN RA BALLMAN DK COFFEY WH FOSTER PS QUIGLEY FK SMITH A MONTHLY REPORT FOR DECEMBER 1967. CRAWFORD RF GUNN RJ ROADS DC YANKA DE DOUGLAS B KNAUP LR ROBERTSON CD PRESENT ADDICOTT FT ETHYL CORP HART MJ KLINGMAN DL LEOPOLD AC MORRE DJ RIFKIN EB US RUBBER MILLARD J REPORT OF PAPERS PRESENTED AT THE THIRD CONFERENCE ON DEFOLIATION HELD AT THE U.S. ARMY BIOLOGICAL LABORATORIES, FT. DETRICK, MARYLAND, AUGUST 10-11, 1965 (GH-P278). AM CYANAM1D DEMAREE K FMC CORP FOY CL HKR HOLM RE KOCH SD LEASURE JK MAGEE RJ MINARIK CE PENNSALT CHEM PURDUE RES FOUND RUHET VL TRUCHELUT GB USDA NEIL ED WI5HESSER MJ Jh -(T ro o NUMBER DATE COPYEE1 CHAMPLAIN CE HUTCH DJ RGH WILCOX RD DOCUMENT 1710 07/12/67 AUTHOR: MARRONE S ADDRESSEE: COPYEE: BARKER RW GROENING WA DOCUMENT 1711 03/17/67 TYPE PAGES EHB JOHNSTON H RHB WR CONTRACT 78 US ARMY BIO LAB BARRONS KC HANES JH REPORT 32 AUTHOR: BRUYNSHAYLETT JP ADDRESSEE: COPYEE: AWS DAVIDSON JH JHD JS RCH DOCUMENT 1712 02/05/53 AUTHOR: DOW ADDRESSEE COPYEE: ECB SOUTHWICK L DOCUMENT 1713 01/04/67 AUTHOR: DOW ADDRESSEE COPYEE: AJS DOAN LA GERONIMO JO KCB TRN DOCUMENT 1714 06/16/58 AUTHOR: COULTER LL ADDRESSEE: COPYEE: ALLEN WW COON ET FOSTER T KELLY JA MCINTYRE HH r o RAYNOR RN SEEKER B DOW SAFRICA CAB EEK JHG KCB RGH REPORT NATION HA NUTTING HS TODD C 11 REPORT NAULT JD CEO EEK I ERL PDL TWH 9 REPORT 8 DOW BRITTON JW DOSSER B GENDREGSKE SA LEASURE JK MULLISON WR RICHARD WF SMITH HL * c< b - ( T ' TITLE GORING CA KCB TRN HAMAKER JH NORTON FH TNH PAGE 245 CONTRACT DAAA13-67-C-0218 AWARD/CONTRACT. BOUNDY RH LEDLIE RB GRAHAM EL WRIGHT RM FIELD TRIALS FOR THE CONTROL OF AMERICAN BRAMBLE (RUBUS CUNEIFOLIUS) AND LANTANA (LANTANO CAMARA) IN SOUTH AFRICA USING TORDON ALONE AND IN COMBINATION WITH 24D 245T DURING 1963 TO 1966 (CRI 146334) (GHP-467). CAG CTL EHB ERL JLS JPB LLC MGW TWH WPF CHEMICAL BRUSH CONTROL ON DITCH BANKS ALONG FENCE ROWS AND IN PASTURES. ROWE VK SMITH A HERBICIDAL ACTIVITY OF HERBICIDE IMIDAZOLE SALTS (REPORT NO. GS-809) (CRI 14 8626). CTL DEP EHB GEL JDE JWV RCH RLG WRD AQUATIC VEGETATION CONTROL WITH KURON (ACD PROJECT STATUS REPORT ROI 16793). COLBY RW FAYERWEATHER BL GIBSON JW LUTZ EM NATION HA RITTY PM SWEZEY AW CONNER DL FISHER JR JOHNSON JE MADDOX JF PEARSE FS ROWE VK VANVALKENBURG W 8 h NUMBER DATE HARDEN RL DOCUMENT 1715 03/12/62 AUTHOR ANDERSON1 LD TODD FE ADDRESSEE COPYEE DOCUMENT 1716 AUTHOR DOW ADDRESSEE COPYEE DOW 03/01/54 DOCUMENT 1717 10/13/55 AUTHOR ALQUIST FH COHEN SI DOH KELLY BE NALE TW SOUTHWICK L US RUBBER ADDRESSEE COPYEE DOW COLBY RW GIBSON JH KAGY JF RAYNOR RA DOCUMENT 1718 01/26/56 AUTHOR SPURRIER EC ADDRESSEE COPYEE DOCUMENT 1719 AUTHOR DOW ADDRESSEE COPYEE DOW 02/10/59 DOCUMENT 1720 07/09/65 AUTHOR ROWE VK ADDRESSEE UNIV OF PA COPYEE GORDON HL PETERSON JE y to to TYPE PAGES WATSON AJ REPORT ATKINS ELJR MCGREGOR SE 2 REPORT SWEZEY AW FISHER JR A REPORT 32 AM CYANAMID COLUMBIAN SOUTHERN Cf DUPONT KELLY JA PACIFIC COAST BORAX STAMLER LM WEEKS DC ALQUIST FN COLLIER B GRAY HE LEMBRIGHT H WARDEN RL PRESENT REPORT 2 REPORT WARDEN RL CRAIN HD 1 LETTER 2 DOW KLIGMAN AM HOLDER BB SILVERSTEIN L TITLE WILSON JS WILTSE MG TOXICITY OF PESTICIDES TO HONEY BEES UNIV OF CA USDA PAGE 246 SIXTH ANNUAL CALIFORNIA NEED CONFERENCE SACRAMENTO (ROI 4005). FRAUCHER RS NARREN LE HANDBOOK OF BIOLOGICAL DATA HERBICIDES. (11593). PHYSICAL CHEMICAL & TOXICOLOGICAL DATA ON HERBICIDES FOR THE HANDBOOK BIOLOGICAL DATA, AMERICAN INSTITUTE OF BIOLOGICAL SCIENCES. BERHENKE LF CARSIDE AND GANNON CHEM (EM C O X TR DESSER RC DUTTON WC GALLOWHUR CHEM KROEGER AP MON ROWE VK SICILIANO NJ TRASK AD UNION CARBIDE & CARBON WHITE LC WITMAN ED OF BARRONS KC DAVIDSON JH HEATH SB NATION HA WATSON AJ BOUNDY RH DIETER CE JOHNSON JE NORTON TR LIVESTOCK POISONING FROM HEED CHEMICALS (ROI 11541). TOXICOLOGY KURON, BARON AND RADAPON (ROI 20750). THORSON SE HUMAN & RABBIT TEST WITH TCDD CTTL. ROME VK HOYLE HR KRAMER NUMBER DATE TYPE DOCUMENT 1721 00/00/69 REPORT AUTHOR: DOM ADDRESSEE: EASTERN REGIONAL RENEGOT COPYEE: PAGES 31 DOCUMENT 1722 AUTHOR: DOM ADDRESSEE COPYEE: 12/30/64 SPEC 1 DOCUMENT 1723 00/ 00/66 NENS 18 AUTHOR: ADDRESSEE: COPYEE: PENNER D GUNTHER FA REPORT ASHTON FM DOM DOCUMENT 1724 00/ 00/68 AUTHOR: CHESTERFORD PARK ADDRESSEE: COPYEE*. NEMS REPORT RES STA JONES KH 5 DOCUMENT 1725 AUTHOR: DOM ADDRESSEE: COPYEE: DOM 02/01/69 REPORT HOPKINS J 1 DOCUMENT 1726 AUTHOR: DOM ADDRESSEE: DOM COPYEE: DOM 03/13/53 LETTER ROME VK SMITH HL BRITTON JM 4 DOCUMENT 1727 03/15/54 ABSTRACT 1 AUTHOR: DOM ADDRESSEE: COPYEE: HYMAS TA U e h -(Z ro CO TITLE PAGE SUPPLEMENTAL REPORT TO THE RENEGOTIATION BOARD ON 670000 RENEGOTIABLE SALES AND PROFITS. 247 245 TRICHLOROPHENATE BOEHRINGER (ANALYTICAL LABORATORIES REPORT). BIOCHEMICAL AND METABOLIC CHANGES IN PLANTS INDUCED BY CHLOROPHENOXY HERBICIDES (FATE OF HERBICIDES IN PLANTS, AND EXTENSIVE BIBLIOGRAPHY)(RESIDUE REVIEWS 14, 83-113). UC DAVIS NACA SPRINGER VERLAG ACUTE TOXICITY DATA FOR PESTICIDES. NOAKES DN SANDERSON DM 245T COMPETITIVE SAMPLE ANALYSIS. DISCUSSION OF TOXICOLOGICAL INFORMATION RELATIVE TO DOW ESTERON BRUSH KILLER. JOHNSON JE SOUTHWICK L SUMMARY OF TOXICOLOGICAL INFORMATION ON 24D AND 245T TYPE HERBICIDES AND AN EVALUATION OF THE HAZARDS TO LIVESTOCK ASSOCIATED WITH THEIR USE (ACETIC ACID (245-TRICHL0R0PHEN0XY) TOXICITY OF ESTERS). ROWE VK NUMBER DOCUMENT 1728 AUTHOR: DOW ADDRESSEE: COPYEE: DATE 06/15/64 DOCUMENT 1729 AUTHOR: ADDRESSEE: COPYEE: 07/03/69 DOCUMENT 1730 AUTHOR: ADDRESSEE: COPYEE: 07/07/69 DOCUMENT 1731 07/30/69 AUTHOR: FLEISCHMANN WJ ADDRESSEE: COPYEE: DOCUMENT 1732 02/12/60 AUTHOR: AZ RECORD ADDRESSEE: COPYEE: DOCUMENT 1733 AUTHOR : USDA ADDRESSEE: COPYEE: 00/00/64 DOCUMENT 1734 02/26/65 AUTHOR: GROTH DM ADDRESSEE: UPTON ET COPYEE: DOCUMENT 1735 00/00/65 AUTHOR: ROMANCIER RM ADDRESSEE: COPYEE: TYPE PAGES ABSTRACT 1 OLSON KJ TITLE PAGE R E S U L T S OF R A N G E F I N D I N G T E S T S ON 245T, METHYL SULFOXIDE, POLYPROPYLENE GLYCOLS. TAYLOR ML 248 NEWS 1 COMMITTEE MAILS PETITIONS TO HALT PINAL DEFOLIATION. REPORT 4 SPRAY DAMAGE COMPLAINTS 690624 TO 690707. REPORT 6 USDA'S USE OF 24D, 245T AND SILVEX IN ARIZONA C T T L . NEWS 1 HEALTH ORGANIZATION REITERATES CALL FOR CONGRESSIONAL PROBE. REPORT 15 ROMANCIER RM 24D, 245T AND RELATED CHEMICALS FOR WOODY PLANT CONTROL IN THE SOUTHEASTERN U.S. (REPORT 16). GA FOREST RES CNCL LETTER HEW THA 1 THANK YOU TO THA FOR SAMPLES TO BE USED IN TESTING FOR CONTAMINANTS OF 245T CTTL. REPORT 4 24D, 245T AND RELATED CHEMICALS FOR WOODY PLANT CONTROL IN THE SE U.S. (REPORT 16). SE FOREST EXP STATION USDA GA FOREST RES CNCL -C U) to o HUMBER DATE DOCUMENT 1736 00/00/64 AUTHOR: PALMER JS ADDRESSEE COPYEE TYPE PAGES REPORT 8 RADELEFF RD DOCUMENT 1737 00/00/69 REPORT AUTHOR AG EXP STATION HUNTINGDO WAY JM ADDRESSEE: COPYEE: 26 DOCUMENT 1738 00/00/57 REPORT AUTHOR: AG EXP STATION PURDUE ADDRESSEE COPYEE: ROBERTS RE 3 DOCUMENT 1739 00/00/68 REPORT 7 AUTHOR: COURTNEY KD ADDRESSEE: COPYEE NIEHS DOCUMENT 1740 00/00/69 REPORT 37 AUTHOR: ADDRESSEE: COPYEE: FDA POSSICK P HEW SMITH D DOCUMENT 1741 AUTHOR: ADDRESSEE: COPYEE 01/20/60 REPORT 9 DOCUMENT 1742 12/08/67 ABSTRACT 20 I h *(T AUTHOR ADDRESSEE: COPYEE: to O! TITLE PAGE 249 THE TOXICOLOGIC EFFECTS OF CERTAIN FUNGICIDES AND HERBICIDES ON SHEEP AND CATTLE (NY ACAD SCI ANN 3,729-736). USDA TOXICITY AND HAZARDS TO MAN DOMESTIC ANIMALS AND WILDLIFE FROM SOME COMMONLY USED AUXIN HERBICIDES (RESIDUE REVIEWS 26, 37-62). THE EFFECTS OF 245T BRUSH SPRAY ON TURKEYS (POULTRY SCIENCE 36,703-705). ROGERS BJ 245T IN THE RAT EXCRETION PATTERN, SERUM LEVELS, PLACENTAL TRANSPORT, AND METABOLISM (PESTICIDES SYMPOSIA)(INTER AMERICAN CONF ON TOX AND OCCUPATIONAL MEDICINE, UHIV OF MIAMI, 277-283). A HEALTH SURVEY OF WORKERS IN A 24D AND 245T PLANT, WITH SPECIAL ATTENTION TO CHLORACNE, PORPHYRIA CURANEA TARDA AND PSYCHOLOGIC PARAMETERS. METTER G POLAND AP EFFECTS OF HERBICIDES ON LIVESTOCK (SOUTHERN WEED CONF 600120) CT T L . PETITION FOR THE ESTABLISHMENT OF TOLERANCES FOR THE PESTICIDE C H E M I CAL, (2 4 5 T ) ON RAW A G R I C U L T U R A L C O M MODITIES, SEC C, FULL REPORTS OF INVESTIGATIONS RE 245T(V0LUME 2 M 2 4 5 T CANCELLATION P R O C E E D I N G S , S U M M A R I E S OF D O W ' S S U B M I S S I O N S TO T H E EPA, 1). NUMBER DATE DOCUMENT 17A3 00/00/57 AUTHORi SCHULZ KH ADDRESSEE COPYEE DOCUMENT 1799 12/00/67 AUTHOR: ADDRESSEE COPYEE DOCKTER MIDWEST RES INST DEPT OF THE ARMY DOCUMENT 1795 AUTHOR ADDRESSEE! COPYEE 00/00/69 DOCUMENT 1796 00/00/65 AUTHOR! SCULTZ KH ADDRESSEE COPYEE DOCUMENT 1797 09/27/68 AUTHOR: ADDRESSEE COPYEE: CAMPBELL HUANG A AD DOCUMENT 1798 09/19/66 AUTHOR: BIRMINGHAM DJ ADDRESSEE COPYEE: DOCUMENT 1799 02/11/67 AUTHOR! WEYLAND ADDRESSEE COPYEE TYPE PAGES TITLE PAGE 250 REPORT 26 CLINCAL AND EXPERIMENTAL INVESTIGATIONS C O N C E R N I N G THE ETIOLOGY OF CHLORACNE (ARCH KLIN EXP. DERM 206, 589-596). SLA TRANSLATIONS CENTER AUTH REPORT GADBERRY HM 20 PHENOXY HERBICIDE RESIDUES AND THEIR PERSISTENCE. GOODMAN LH HOUSE MB CHART 1 PRESENCE OF CHLORACNEGEN AND TCDD IN 295T FROM VARIOUS MANUFACTURERS. REPORT 6 CLINICAL PICTURE AND ETIOLOGY OF CHLORACNE. STS SCIENTIFIC TRANSLATI UNIV DERMATOLOGY CLINIC NEWS REPORT FDA RESS J 2 CHEMICAL AND TOXICOLOGICAL EVALUATIONS OF ISOLATED AND SYNTHETIC CHLORO DERIVATIVES OF DIBENZO-P-DIOXIN. FIRESTONE D VERRETT J HIGGINBOTHAM GR REPORT HEW 9 OCCUPATIONAL CHLORACNE (PROCEEDINGS INTL CONGRESS ON OCCUPATIONAL HEALTH, 753-755)(VIENNA, 660919 TO 660929). KEY MM WAYNE ST UNIV PROC 2 PREPARATION OF TRICHLOROPHENOXY ACETIC ACID AVOIDING THE FORMATION OF CHLORAKNE EXCITERS. to U) -C. 0 5 %> D n*TC rvnj: DOCUMENT 1750 02/11/67 AUTHOR: CH BOEHRINGER SOHN ADDRESSEE: DON COPYEE: LETTER DOCUMENT 1751 05/20/61 REPORT n r*rr<j 1 10 AUTHOR: BAUER H ADDRESSEE COPYEE DOCUMENT 1752 02/15/57 AUTHOR: DON ADDRESSEE: DON COPYEE: DON MCCOY HJ DOCUMENT 1753 AUTHOR: DON ADDRESSEE: DON COPYEE: DON 02/22/65 DOCUMENT 1754 AUTHOR: ADDRESSEE: COPYEE: 00/00/69 DOCUMENT 1755 AUTHOR: ADDRESSEE: COPYEE: 00/00/69 DOCUMENT 1756 AUTHOR: ADDRESSEE: COPYEE: 00/00/53 HAMBURG LETTER RONE VK DIXON NR CORBIN NL PLETCHER DE 2 LETTER PLETCHER DE GILL HH PLETCHER DE 3 REPORT 3 REPORT 15 REPORT 2 C . <S ^ 3 TIT*THE CHLORAKNE. PREPARATION OF TRICHLOROPHENOL PAGE 251 OCCUPATIONAL INTOCICATION OCCURINO IN THE PRODUCTION OF CHLOROPHENOL COMPOUNDS (EFFECTS OF 245T ON MAN AND THE ENVIRONMENTKHEARINGS BEFORE THE SUBCOMMITTEE ON ENERGY, NATURAL RESOURCES, AND THE ENVIRONMENT OF THE COMMITTEE ON COMMERCE UNITED STATES SENATE NINETYFIRST CONGRESS SECOND SESSION ON EFFECTS OF 245T ON MAN AND THE ENVIRONMENT. 700407 AND 700415. SERIAL 91-60, 241-249). SHULZ KH SPIEGELBERO U INFORMATION GIVEN TO TCC ST LOUIS, MO ON CHLORACNE, TCDD, CLEAN-UP AFTER PLANT ACCIDENT CTTL. COWELL JH HOLDER BB "EXCITER" PROBLEM MEETING 650222. LYNN GE DOEDENS JD CHRONOLOGY OF CHLORACNE TESTING IN B RL. THE TERATOGENIC POTENTIAL OF 245T. TCDD UNLIKELY TO BE ENCOUNTERED BY ANIMAL OR MAN IN SUFFICIENT DOSAGE TO CAUSE TOXIC REACTION CTTL. NUMBER DOCUMENT 1757 AUTHOR ADDRESSEE: COPYEE: DAATTEE 00/00/69 TT YY PPEE MEMO PAGES 21 DOCUMENT 1758 00/00/65 REPORT AUTHOR SCIENTIFIC TRANSLATION S SCULTZ KH ADDRESSEE COPYEE 6 DOCUMENT 1759 AUTHOR: ADDRESSEE COPYEE 06/00/63 NEWS REPORT 5 DOCUMENT 1760 06/26/62 REPORT 5 AUTHOR J O N E S EL ADDRESSEE: COPYEE: DOCUMENT 1761 00/00/68 AUTHOR: BLUMENTHAL R ADDRESSEE COPYEE: DOCUMENT 1762 09/00/60 AUTHOR: D A N I E L S O N LL ADDRESSEE: COPYEE DOCUMENT 1763 00/00/69 AUTHOR BERG GG ADDRESSEE COPYEE KRIZEK H REPORT REPORT SHEETS TJ REPORT MILLER MH 3 10 <\ TITLE PAGE 252 SUMMARY AND CONCLUSIONSAPPENDIX 2)(REPORT OF THE ADVISORY PANEL ON TERATOGENICITY OF P E S T H E F F E C T S OF 245T ON MAN AND THE ENVIRONMENT). CLINICAL PICTURE AND ETIOLOGY OF CHLORACNE (EFFECTS OF 245T ON MAN AND THE ENVIRONMENT). UNIV DERMATOLOGY CLINIC INDUSTRIALLY ACQUIRED PORPHYRIA!EFFECTS OF 245T ON MAN AND THE ENVIRONMENT). A TECHNIC FOR TESTING ACNEGENIC POTENCY IN RABBITS, APPLIED TO THE POTENT ACNEGEN TCDD (PRESENTED AT THE TWENTY-THIRD ANNUAL MEETING OF THE SOCIETY FOR INVESTIGATIVE DERMATOLOGY)(EFFECTS OF 2A5T ON MAN AND THE ENVIRONMENT). UNIV OF CHICAGO U.S. SHOWS SIGNS OF CONCERN OVER EFFECT IN VIETNAM OF 9 YEAR DEFOLIATION PROGRAM (EFFECTS OF 245T ON MAN AND THE ENVIRONMENT). HERBICIDES IN SOILS (ARS 20-9, 170-181)(EFFECTS OF 245T ON MAN AND THE ENVIRONMENT). USDA SOIL PERSISTENCE OF 2A5T (CHEMICAL FALLOUT CURRENT RESEARCH ON PERSISTENT PESTICIDES). NUMBER DOCUMENT 1764 AUTHOR: DOM ADDRESSEE COPYEE: DATE 01/00/61 TYPE PAGES PRESENT 9 REPORT RITTY PM DOCUMENT 1765 AUTHOR DOW ADDRESSEE: COPYEE: 00/00/69 REPORT 7 DOCUMENT 1766 AUTHOR: ADDRESSEE: COPYEE: 00/00/69 REPORT 27 DOCUMENT 1767 10/03/63 REPORT AUTHORS GEWERBEHYGIENISCH PHARMA OETTEL H ADDRESSEE! COPYEE: 16 DOCUMENT 1768 00/00/60 AUTHOR: CORNELL U AG DP ADDRESSEE-* COPYEE: ALEXANDER M REPORT 10 WHITESIDE JS LICHY CT DOCUMENT 1769 AUTHOR: DOW ADDRESSEE: COPYEE: 09/28/64 REPORT LUECK AF 1 DOCUMENT 1770 01/12/65 AUTHOR-- GROTH DH ADDRESSEE HEW PUB HLTH COPYEE: CHRISTIAN D REPORT 10 HEW PUB HLTH HEW PUB HLTH SERV KRAUS GE DOCUMENT 1771 AUTHOR: DOW ADDRESSEE: rnpv[f: 00/00/69 REPORT KENAGA EE 5 sbeb'cr TO TITLE PAGE 253 WHAT HAPPENS TO PHENOXY HERBICIDES WHEN APPLIED TO A WATERSHED AREA CNE WEED CONTROL CONF). WINSTON AW DEFOLIATION, THE COSTS THAT LINGER. SUPPLEMENTAL REPORT TO THE RENEGOTIATION BOARD ON 670000 RENEGOTIABLE SALES AND PROFITS. NEUERE ERKENNTNISSE UBER GESUNDHEITSGEFAHRLICHE ARBEITSSTOFFE ( M O D E R N E U N F A L L V E R H T U N G H E F T 8 ). MEASUREMENT OF MICROBIOLOGICAL EFFECTS OF HERBICIDES (WEEDS 8/204-213, 1960). LYNN GE ROWE VK CHLORACNE STATUS REPORT 640700 TO 640900. IDENTIFICATION OF THE TOXIC FACTOR IN 245T. TORDON HERBICIDES-EVALUATION OF SAFETY OF FISH & BIRDS (DTE 25(1) 5-9). "J. DOCUMENT 1772 10/00/51 AUTHOR i DOH ADDRESSEE COPYEE DOCUMENT 1773 AUTHOR DOM ADDRESSEE' COPYEE 09/20/55 DOCUMENT 1774 AUTHOR: DOH ADDRESSEE COPYEE: 08/18/54 DOCUMENT 1775 00/00/69 AUTHOR BELYAVSKAYA LI ADDRESSEE' COPYEE DOCUMENT 1776 11/09/65 AUTHOR DOM OYEN F ADDRESSEE' COPYEE DON ELSHERE D JONES GD MULLISON HR DOCUMENT 1777 05/19/60 AUTHOR DOH ADDRESSEE: COPYEE: DON COLBY RM HAMMER OH KAGY JF MCINTYRE HH HRIGHT N REPORT HYMAS TA 8 TECH 1 TECH 2 ABSTRACT 1 IZD SARATOV UNIV REPORT 11 LYNN GE LYNN GE G O RDO N HL KAGY JF MILSON AH REPORT OLSON KJ RITTY PM ELSHERE D HART A K I LIA N DJ PERKINS RP 12 ) b h `( T TO cn o PAGE 254 TIT SUMMARY OF TOXICOLOGICAL INFORMATION ON 24D 245T TYPE HERBICIDES & AN EVALUATION OF THE HAZARDS TO LIVESTOCK ASSOCIATED WITH THEIR USE (AMERICAN JOURNAL OF VETERINARY RESEARCH 15(57), 622-629). ROHE VK ISOPROPYLESTER 24D, ISOPROPYL ESTER. ACID SLURRY. PETERSON J TOXIC EFFECT OF SOME HERBICIDES ON FISH AND AQUATIC INVERTEBRATES(VIDOVOI SOSTAV EKOL PROD GIDROBIONTOV VOLGOGRAD VODOKHRAN 93(8)) (CHEMICAL ABSTRACTS, VOL. 72, 1970, PG 240) KONSTANTINOV AS KONSTANTINOVA NS SKIN IRRITATION AND ACNEGENIC PROPERTIES OF VEON BRUSH KILLER, VEON 245T, TORDON 101 AND MEEDAR 245T AMINE (BIOCHEMICAL RES LAB) (BC T2.2-139-2). OHARE CP OLSON KJ BARRONS KC GOHELL JH KILIAN DJ HILTSE MG BOUNDY RH JOHNSTON RV MOSS RD RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON AGRICULTURAL CHEMICAL FORMULATION M-1677 (BIOMEDICAL RES LAB) (BC T 2 .30-180-1). OYEN F RITTY PM BARRONS KC GAY HH HYMAS TA LUCE EN STENGER VA BOUNDY RH GREENE LM JONES GD LYNN GE TISDALE HL NUMBtK DOCUMENT 1778 DATE 03/09/65 AUTHOR ADDRESSEE COPYEE DOM OYEN F DOM ELSHERE D JONES GD MULLISON MR DOCUMENT 1779 AUTHOR DOM ADDRESSEE DOM COPYEE 07/06/59 DOCUMENT 1780 AUTHOR DOM ADDRESSEE' COPYEE 05/10/57 DOCUMENT 1781 AUTHOR DOM ADDRESSEE COPYEE: 05/20/57 DOCUMENT 1782 AUTHOR DOM ADDRESSEE COPYEE 05/20/57 DOCUMENT 1783 11/20/57 AUTHOR ADDRESSEE COPYEE DOM DOM COLBY RM GREENE LM K I L I A N DJ MUSSELL DR MRIGHT N TYPE REPORT PAGES 10 LYNN GE LYNN GE GORDON HL KAGY JF MILSON AM LETTER MOLF MA COULTER LL 2 REPORT 1 REPORT I DB REPORT 1 1 REPORT HOYLE HR A L L I N S O N RL ELSHERE D HART A LUCE EN PERKINS RP 5 y ro U) -c NI TITLE Pt 2 SKIN IRRITATION AND ACNEGENIC PROPERTIES OF VEON BRUSH KILLER, VEON 245T, TORDON 101 AND WEEDAR 245T AMINE (BIOCHEMICAL RES LAB) (BC T2.2-139-2). OHARE CP OLSON KJ BARRONS KC GOMELL JH K I L I A N DJ MILTSE MG BOUNDY RH JOHNSTON RV MOSS RD ESTERON FORMULATIONS MIXED WITH FUEL OIL CONSIDERED MORE IRRITATING THAN FORRON OR ESTERON FORMULATIONS DILUTED WITH WATER CTT L . SAMPLE 2 M-1116.DILUTION T2.30-101-1 SKIN CONTACT IRRIGATION. SAMPLE 2 M-1116 DILUTION(T2.30-101-1)(EYE CONTACT TEST). S A M P L E 2, M-1116, D I L U T I O N C - 1 - 1 4 - 1 0 0 ( T 2 . 3 0 - 1 0 1 - 1 ) ( T O X I C O L O G Y WOR K SHEET). M-1116 DILUTION Cl-14-100 (DATA SHEET OF PROPERTIES, HEALTH, AND PRECAUTIONS FOR SAFE HANDLING OF MATERIALS). MCCOLLISTER DD OLSON KJ BESHGETOOR GAY HH HYMAS TA LYNN GE SCOLES GW AW BOUNDY RH GRAY HE KAGY JF MCINTYRE HH TISDALE WL NUMBER DOCUMENT 1784 AUTHOR: DOM ADDRESSEE: COPYEE: DATE 11/30/57 TYPE PAGES REPORT 2 MCCOLLISTER DD DOCUMENT 1785 AUTHOR: DOM ADDRESSEE: DOM COPYEE: DOM 04/07/60 MEMO MOLF MA MCINTYRE HH MOLF MA 1 DOCUMENT 1786 10/00/54 NEMS 8 AUTHOR DOM ADDRESSEE COPYEE: REPORT HYMAS TA DOCUMENT 1787 08/10/67 AUTHOR BUERGE J SADEK SE ADDRESSEE COPYEE REPORT DUNN FL TINKER B 33 DOCUMENT 1788 00/00/65 TEST 1 AUTHOR: DOM ADDRESSEE: COPYEE ROHE VK DOCUMENT 1789 07/09/65 LETTER AUTHOR: ADDRESSEE: COPYEE DOM HOSPITAL DOM HOYLE HR OF UNIV OF PA ROME VK KLIGMAN AM ROHE VK KRAMER CG 2 DOCUMENT 1790 AUTHOR: DOM ADDRESSEEt COPYEE: 06/22/67 CHART REPORT ELLIS SD 1 TITLE PAGE RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON INVERTON (M-l116)(DILUTION Cl-lA-lOO)( T 2 .30-101-1). OLSON KJ 256 COMMENTS ON THE LETTER FROM WEIL CONCERNING ESTERON 99 CONCENTRATE AND DOW 245T AMINE WEED KILLER. SUMMARY OF TOXICOLOGICAL INFORMATION ON 24D AND 2A5T TYPE HERBICIDES AND AN EVALUATION OF THE HAZARDS TO LIVESTOCK ASSOCIATED WITH THEIR USECAM JOUR OF VETERINARY RES 15(57), 622-629). ROWE VK REPORT ON HISTOPATHOLOGIC EXAMINATION OF RAT TISSUES TCDD. L MYER MOSS M SUGGESTED PROTOCOL FOR STUDIES ON HUMAN SUBJECTS TO DETERMINE THE ACNEGENIC POTENTIAL OF TCDD AND TO STUDY THE PATHOGENESIS OF CHEMICALLY INDUCED ACNE. COVER LETTER FOR PROTOCOL ON TCDD STUDIES WITH HUMAN SUBJECTS C T T L . STUDIES ON HUMAN SUBJECTS C T T L . GORDON HL PETERSON JE HOLDER BB SILVERSTEIN L CLINICAL CHEMISTRYiTCDD)(66681-1). NUMBER DATE DOCUMENT 1791 08/08/67 AUTHOR BUERGE JF ADDRESSEE: COPYEE: DOCUMENT 1792 08/10/67 AUTHOR! BUERGE JF ADDRESSEE: COPYEE: DOCUMENT 1793 AUTHOR: DON ADDRESSEE! COPYEE: 06/19/67 DOCUMENT 1799 AUTHOR: ADDRESSEE: COPYEE: 00/00/67 DOCUMENT 1795 AUTHOR: DOM ADDRESSEE: COPYEE: 00/00/67 DOCUMENT 1796 AUTHOR: DOM ADDRESSEE: COPYEE: 12/ 02/66 DOCUMENT 1797 AUTHOR: DOM ADDRESSEE: COPYEE: 01/10/67 DOCUMENT 1798 AUTHOR: DOM ADDRESSEE: COPYEE: 01/10/67 TYPE CHART REPORT DOM PAGES 1 REPORT DOM 1 CHART REPORT TINKER BP 2 CHART REPORT 8 REPORT 9 CHART REPORT OHARE CP 3 REPORT OHARE CP 1 REPORT OHARE CP 1 TITLE SUMMARY OF HEMAT0L0GY(TCDDH66681-1) . PAGE 257 HEMATOLOGY SUMMARY(TCDD)(CLASS D C R A B B I T S , ACUTE ORAL) (66681-1). OYEN F TCDDC66681--1 ). SUMMARY OF HEMATOLOGY(TCDD)(66681-1) CTTL. SUMMARY OF EFFECT OF TCDD ON RABBITSACUTE ORAL)(66681-1). SUMMARY OF HEMATOLOGY(TCDD)(66681-1). BONE MARROW SUMMARYCTCDDM66681-1). HEMATOLOGY SUMMARY(TCDD)C66681-1). SADEK. S NUMBER DOCUMENT 1799 AUTHOR: DON ADDRESSEE: COPYEE: DATE 11/07/66 DOCUMENT 1800 AUTHOR: DON ADDRESSEE: COPYEE: 10/28/66 DOCUMENT 1801 AUTHOR: DON ADDRESSEE: COPYEE: 10/27/66 DOCUMENT 1802 AUTHOR: DON ADDRESSEE: COPYEE: 11/04/66 DOCUMENT 1803 11/04/66 AUTHOR CRANER EN ADDRESSEE: COPYEE: DOCUMENT 1804 AUTHOR: DON ADDRESSEE: COPYEE: 11/04/66 DOCUMENT 1805 AUTHOR: DON ADDRESSEE: COPYEE-' 11/04/66 DOCUMENT 1806 AUTHOR: DON ADDRESSEE' COPYEE' ti U) r o c/i rf* 04/21/67 TYPE PAGES CHART REPORT ELLIS SD 1 REPORT OYEN F 2 REPORT SADEK SE 1 CHART REPORT OYEN F 3 CHART REPORT DON 2 REPORT OYEN F 1 CHART REPORT TINKER BP 13 REPORT TINKER BP 1 TITLE CLINICAL CHEMISTRY(TCDD)(66681-1) KOSES AA PAGE 258 MICRO PATHOLOGICAL FINDINGS(TCDD)(66681-1) CTTL. S U M M A R Y O F G R O S S M I C R O P A T H O L O G I C A L F I N D I N G S ( T C D D K 6 6 6 8 1 - 1 ). S U M M A R Y OF G R O S S 8 M I C R O P A T H O L O G Y ( T C D D ) ( 6 6 6 8 1 - l ). ORGAN WEIGHT SUMMARY(TCDD)(66681-1). TCDDC66681-1). TCDDC66681-1). TCDD(66681-1) NUMBER DOCUMENT 1816 AUTHOR: DON ADDRESSEE' COPYEE: DATE 12/03/64 DOCUMENT 1817 08/10/67 AUTHOR: SADEK SE ADDRESSEE' COPYEE: DOCUMENT 1818 AUTHOR: DON ADDRESSEE: COPYEE 02/27/61 DOCUMENT 1819 AUTHOR: DON ADDRESSEE: COPYEE: 00/00/61 DOCUMENT 1820 AUTHOR: DON ADDRESSEE' COPYEE: 03/06/61 DOCUMENT 1821 05/03/54 AUTHOR: ADDRESSEE COPYEE: DON DON BARRONS KC COLBY RN JOHNSTON H LYNN GE NHITE LC DOCUMENT 1822 00/00/69 AUTHOR: BELYAVSKAYA LI ADDRESSEE! COPYEE: TYPE TECH PAGES 1 DATA REPORT 159 REPORT OLSON K 1 REPORT 6 STEVENSON HJ REPORT OLSON K 1 REPORT 35 MCCOLLISTER DD A L L I N S O N RL BESHGETOOR DAVIDSON JH KAGY JF MACCUTCHEON NRIGHT N SM ABSTRACT 1 KONSTANTINOV AS -C r o ) o r cn TITLE TCDD(TOXICOLOGY WORK SHEETK66681-1) PAGE 260 REPORT ON HISTOPATHOLOGIC EXAMINATION OF RABBIT TISSUES TCDD (T36.25-66681-1). DOWANOL PIB MIX ESTERS OF 245T(EYE CONTACT TEST). DOWANOL PIB MIX ESTER OF 245T(ACUTE ORAL TOXICITY). TOMPSON E DOWANOL PIB MIX ESTER OF 245T (TOXICOLOGY WORK SHEET). RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON BUTYL (AND ISOBUTYL)(245 TRICHLOROPHENOXY) ACETATE. OYEN F ALQUIST FN BOUNDY RH GAY HH KELLY JA MARTIN D WRIGHT P BACON KD BRITTON EC GREENE LM LUCE EN SUNDERLAND WW TOXIC EFFECT OF SOME HERBICIDES ON FISH AND AQUATIC INVERTEBRATES (VIDOVOI SOSTAV EKOL PROD GIDROBIONTOV VOLGOGRAD VODOKHRAN 93(8)(RUSS). KONSTANTINOVA NS USSR NUMBER DOCUMENT 1823 AUTHOR: BT ADDRESSEE: COPYEE: DOM DATE 11/23/66 DOCUMENT 1824 AUTHOR: DOM ADDRESSEE COPYEE 11/09/66 DOCUMENT 1825 11/17/54 AUTHOR: BARRONS KC LYNN GE ADDRESSEE COPYEE: BARRONS KC ALQUIST FN BRUST HF FAYERMEATHER BL KAGY JF NORTON TR SOUTHMICK L DOCUMENT 1826 AUTHOR: JOHNSON ADDRESSEE ROWE VK COPYEE BARRONS KAGY JF 08/24/53 JE KC DOCUMENT 1827 00/00/57 AUTHOR: DERMATOLOGICA ADDRESSEE: COPYEE: DOCUMENT 1828 AUTHOR DOM ADDRESSEE: COPYEE: 12/00/59 DOCUMENT 1829 AUTHOR: DOM ADDRESSEE: COPYEE: 06/01/55 TYPE PAGES REPORT 5 DOM SILVERSTEIN LG REPORT I BT 3 REPORT C O U L T E R LL 33 DOM BOUNDY RH COLBY RM GIBSON JM KELLY JA NUTTING HS SMEZEY AM LETTER DOM DOM LYNN GE ALQUIST FN 1 ABSTRACT 1 IND HYGIENE DIGEST REPORT 3 TECH I HRH 1 TITLE PAGE 261 DIRECT ESTER PLANT 489 BLDG PROCESS SAMPLES (REQUEST FOR SCREENING AND APPLICATION TESTING). BUTYL ESTER OF 245T 489 BLDG DIRECT ESTER PROCESS. ERBON SOIL STERILANT DOW JOHNSON JE JOHNSON JE BRITTON EC COLLIER BL GRAY HE MADDOX JF RAYNOR RN WATSON AJ LYNN GE BRITTON JW DAVIDSON JH HEATH SB NATION HA ROWE VK POTENTIAL USES OF NEW AGRICULTURAL PRODUCT Kll,354. SPENCER HC DOW OCCUPATIONAL ACNE (SO CALLED CHLORACNE) CAUSED BY AROMATIC CYCLIC ETHERS (DERMATOLOGICA 115, 540-546) (INDUSTRIAL HYGIENE DIGEST 590100). KIMMIG J SCHULZ KH ESTERON 245 OS SUMMARY OF TOXICOLOGICAL INFORMATION ON AND PRACTICAL CONSIDERATIONS IN ITS HANDLING AND USE (BIOCHEM RES LAB). 245T DOWANOL 97B ESTER (T25.14-106-1) WOLF MA NUMBER DOCUMENT 1830 AUTHOR DOM ADDRESSEE COPYEE DATE 04/26/57 DOCUMENT 1831 10/10/50 AUTHOR ADDRESSEE COPYEE ADAMS DM SPENCER HC DOM DUTTON MC DOCUMENT 1832 AUTHOR DOM ADDRESSEE COPYEE 05/17/49 DOCUMENT 1833 AUTHOR DOM ADDRESSEE: COPYEE 04/01/49 DOCUMENT 1834 AUTHOR DOM ADDRESSEE COPYEE 03/21/49 DOCUMENT 1835 AUTHOR DOM ADDRESSEE COPYEE 04/12/49 DOCUMENT 1836 03/09/49 AUTHOR DOM ROME VK ADDRESSEE: COPYEE DOCUMENT 1837 AUTHOR DOM ADDRESSEE COPYEE 12/00/49 TYPE PAGES TECH HOYLE HR 1 REPORT DOM STREETER LE ALLEN MM IRISH DD 5 REPORT MYSE H 1 REPORT MYSE H 4 REPORT NYSE H 1 REPORT 1 AUTH I HAS HHITE L 1 REPORT ROME VK 17 TITLE DOWANOL ESTER OF 265T. ROWE VK PAGE 262 RESULTS OF SKIM IRRITATION AND SKIN SENSITIZATION TESTS CONDUCTED ON HUMAN SUBJECTS WITH 26D DOWANOL 97B ESTER (T25.16-97-1). MCCOLLISTER DD ROWE VK BRITTON JW KAGY JF DOSSER RC LYNN GE K7559-2 MIXED AMYL ESTER OF 245T (SINGLE ABSORPTION EXPOSURE RECORD). K7559-2 MIXED AMYL ESTER OF 265TSKIN IRRITATION). MIXED AMYL ESTER OF 265T. K7559-2 MIXED AMYL ESTER OF 265T (ACUTE ORAL TOXICITY). MIXED AMYL ESTER OF 265T. IRISH MCCOLLISTER DD K-6277-6(265T ISOPROPYL E S T E R K A C U T E ORAL TOXICITY). WYSE H NUMBER DOCUMENT 1838 AUTHOR: DOW ADDRESSEE: COPYEE: DATE 05/17/49 TYPE REPORT WYSE H PAGES 1 DOCUMENT 1839 AUTHOR: DOW ADDRESSEE: COPYEE: 03/21/49 REPORT WYSE H 3 DOCUMENT 1840 AUTHOR: DOW ADDRESSEE: COPYEE: 04/14/49 REPORT WYSE H 1 DOCUMENT 1841 02/25/49 AUTHOR: DOW MCCOLLISTER DD ADDRESSEE COPYEE: AUTH I HCS R O W E VIC 1 DOCUMENT 1842 02/00/50 REPORT AUTHOR DEPT OF BOTANY & PLAINT ADDRESSEE COPYEE: FARWELL ED 8 DOCUMENT 1843 06/10/49 AUTHOR: DOW ADDRESSEE MI STATE COLLEGE COPYEE: CONTRACT 5 DOCUMENT 1844 07/01/49 AUTHOR: DOW ROWE VK ADDRESSEE COPYEE REPORT I DDM 1 DOCUMENT 1845 01/20/48 TECH 2 AUTHOR: ADDRESSEE" COPYEE o ro cn oo -JX ADAMS CM DOW TITLE SINGLE ABSORPTION EXPOSURE RECORD PAGE 263 i s o p r o p y l Es t e r o f 2a s t . K6277-A ISOPROPYL ESTER OF 245T (ACUTE ORAL TOXICITY). ISOPROPYL ESTER OF 245T. I RM WHITE L IRISH SOME EFFECTS OF HERBICIDES ON PASTURE AND ON GRAZING L I V E S T O C K S AG EXP STATION QUARTERLY BULLETIN 32(3), 378-385). GRIGSBY BH MI STATE COLLEGE COOPERATIVE RES AGREEMENT. WEED KILLERS (REQUEST FOR BIOLOGICAL TEST). I EWA I HCS RESULTS OF ACUTE ORAL TESTS ON (1) METHYL ESTER OF 245T, (2) ETHYL SALICYLATE, (3) DELTA-HYDROXY QUINOLINE, (A) ALPHA-BROMONAPHTHALENE (T2.2-27-2). ROWE VK NUMBER DOCUMENT 1846 DATE 00/00/69 TYPE ABSTRACT PAGES 1 AUTHOR: B E L Y A U S K A Y A LI ADDRESSEE* COPYEE: KONSTANTINOV AS DOCUMENT 1847 00/00/69 REPORT AUTHOR: MONKS WOOD EXPERIMENTAL ADDRESSEE: COPYE: WAY JM 26 DOCUMENT 1848 08/00/68 AUTHOR: DUNSCOMBE WK ADDRESSEE COPYEE: ABSTRACT 1 DOCUMENT 1849 04/00/52 REPORT 7 AUTHOR: FDA ADDRESSEE! COPYEE: DOCUMENT 1850 10/00/51 AUTHOR FDA ADDRESSEE: COPYEE DOCUMENT 1851 AUTHOR: ADDRESSEE: COPYEE: 10/02/50 DOCUMENT 1852 10/21/52 AUTHOR: DOW ADDRESSEE: BRITTON JW .COPYEE : (j O . LEHMAN AJ REPORT LEHMAN AJ REPORT LETTER ROWE VK SMITH HL 8 1 1 TITLE PAGE 264 TOXIC EFFECT OF SOME HERBICIDE OH FISH AMD AQUATIC INVERTEBRATES (VIDOVOI SOSTAV, EKOL PROD GIDROBIONTOV V O LGOGRAD VODOKHRAN, 93-98)(RUSSIAN). KONSTANTINOVA NS USSR TOXICITY AND HAZARDS TO MAN, DOMESTIC ANIMALS, AND WILDLIFE FROM SOME COMMONLY USED AUXIN HERBICIDES (RESIDUE REVIEWS 26, 37-62). OCCUPATIONAL ACNE, 5 CASES CAUSED BY WEEDKILLERS (MEDICINA CUTANEA 1(3), 225-231 6 6 0 0 0 0 ) . CHEMICALS IN FOODS, A REPORT TO THE ASSOCIATION OF FOOD AND DRUG O F F I C I A L S ON C U R R E N T D E V E L O P M E N T S , P A R T 2, P E S T I C I D E S , S E C T I O N 3, SUBACUTE AND CHRONIC TOXICITY (ASSN OF FOOD & DRUG OFFICIALS OF THE U.S. 16 (2), 47-53). CHEMICALS IN FOODS, A REPORT TO THE ASSOCIATION OF FOOD AND DRUG OFFICIALS ON CURRENT DEVELOPMENTS (PART 2 PESTICIDES)(ASSN OF FOOD 8 DRUG OFFICALS OF THE U.S. 15(4)). ODOR THRESHOLDS, FISH TOXICITY AND PROPERTIES OF WATER AS FOLLOWING CONCENTRATIONS OF 245T CTTL. PAPER ENTITLED "ACUTE AND CHRONIC TOXICITY OF 24D AND 245T IN DOGS" BY DRILL AND HIRATZKA. WILLIAMS GJ NUMBER DATE DOCUMENT 1853 12/15/49 AUTHOR: DON ADDRESSEE: DRILL VA COPYEE* DOCUMENT 1854 AUTHOR: DOW SPENCER ADDRESSEE: COPYEE: 02/24/49 HC DOCUMENT 1855 08/31/50 AUTHOR: DOW ADDRESSEE: BRITTON JW COPYEE: DOW DOCUMENT 1856 07/17/50 AUTHOR: REEVES FC ADDRESSEE: COPYEE: DOCUMENT 1857 00/00/46 AUTHOR: DRILL VA ADDRESSEE COPYEE DOCUMENT 1858 AUTHOR: DOW SPENCER ADDRESSEE: COPYEE: 03/10/49 HC DOCUMENT 1859 02/02/50 AUTHOR: MCCOLLISTER DD ADDRESSEE COPYEE: DOCUMENT 1860 AUTHOR: ADDRESSEE: COPYEE'- DOW WYSE H ro 05 O 12/29/49 TYPE PAGES LETTER 5 ROWE VK WAYNE UNIV AUTH DRILL VA 1 REPORT DRILL VA SPENCER HC LEGAL 2 1 REPORT WAYNE UNIV 12 AUTH IRISH SPENCER HK 6 REPORT ROWE VK 9 AUTH 7 MCCOLLISTER DD TITLE PAGE 265 TOXICITY OF 24D AND 245T (SUGGESTED PROCEDURES FOR TESTING TOXICITY IN DOGS) CTTL 245T REQUEST FOR BIOLOGICAL TEST TO BIOCHEMICAL RESEARCH LABORATORY. MCCOLLISTER DD ROHE VK INTERIM REPORT ON THE ACUTE AND SUBACUTE ORAL TOXICITY OF 2A5T FOR DOGS. ROWE VK NOTARY WITNESSES VICTOR DRILL AS AUTHOR OF RESEARCH REPORT CTTL. ACUTE AND SUB-ACUTE ORAL TOXICITY OF 245T FOR DOGS. 245T (REQUEST FOR BIOLOGICAL TEST). MCCOLLISTER DD ROME VK WHITE L WYSE H THE ACUTE ORAL TOXICITY OF 245T TO RATS, MICE, GUINEA PIGS AND CHICKS CTTL. SPENCER HC THE ACUTE ORAL TOXICITY OF 245T TO RATS, MICE, GUINEA PIGS AND CHICKS CTTL. ROWE VK SPENCER HC 5 h -( NUMBER DOCUMENT 1861 AUTHOR! DOM ADDRESSEE: COPYEE DATE 08/15/50 DOCUMENT 1862 AUTHOR: DOM ADDRESSEE: COPYEE: 08/15/50 DOCUMENT 1865 AUTHOR: ADDRESSEE: COPYEE: 00/00/50 DOCUMENT 1864 AUTHOR: FARMELL ADDRESSEE: COPYEE: 00/00/50 ED DOCUMENT 1865 08/08/45 AUTHOR: DOM ADDRESSEE: ALLEN MM COPYEE: DOM DOCUMENT 1866 AUTHOR: DOM ADDRESSEE: DOM COPYEE: 01/06/53 DOCUMENT 1867 04/30/58 AUTHOR: DOM ADDRESSEE: COPYEE: DOCUMENT 1868 09/20/51 AUTHOR: ADDRESSEE: COPYEE: . ^ tO 05 DOM DOM BRITTON EC HAMMER OH LYNN GE SUNDERLAND WW TYPE REPORT ROME VK PAGES 8 REPORT 4 MCCOLLISTER DD REPORT 3 REPORT GRIGSBY BH 2 REPORT GEISEL C VEAZEY HR ADAMS CM 11 LETTER 2 ROME VK SUNDERLAND MM LABEL 1 REPORT 32 MCCOLLISTER DD ADAMS A BRITTON JH HEAIH SB NELSON ML TITLE PAGE 266 THE ACUTE ORAL TOXICITY OF 245T TO RATS, MICE, GUINEA PIGS AND CHICKS CTTL. SPENCFR HC THE ACUTE ORAL TOXICITY OF 245T TO RATS, MICE, GUINEA PIGS AND CHICKS. ROME VK SPENCER HC DOM 245T (ESTERON 245). PROGRESS REPORT ON DAIRY CATTLE HERBICIDE FEEDING EXPERIMENT. JENSEN JM MI AG EXPERIMENT STATION TOXICITY OF 245T. ROME VK 24D AND 245T LABELS. 24D AND RELATED TYPE HERBICIDEStTOXICOLOGICAL INFORMATION AND SUGGESTIONS REGARDING TREATMENT FOR PERSONS SHALLOMING 24D AND RELATED TYPE HERBICIDES). RESULTS OF TOXICOLOGICAL TEST ON ALPHA 245 TRICHLOROPHENOXY PROPIONIC ACID (T23.14-15-1). ROHE VK BERHENKE L DAVIDSON JH HIRSCHKIND H RECHTIN HJ BRANCH CB DUTTON HC KELLY JA SOUTHMICK L NUMBER DATE DOCUMENT 1869 06/00/64 AUTHOR: APPLEBAUM IL ADDRESSEE: COPYEE: DOCUMENT 1870 10/01/65 AUTHOR ALEXANDER HC ADDRESSEE: COPYEE: ALEXANDER HC BEK CM HAMILTON CE SCHAFFER RB WAAS WE DOCUMENT 1871 00/00/69 AUTHOR: ADDRESSEE: COPYEE: DOCUMENT 1872 AUTHOR: DOW ADDRESSEE: COPYEE: 02/20/65 DOCUMENT 1873 AUTHOR DOW ADDRESSEE: COPYEE: I PJG 07/24/68 DOCUMENT 1874 06/26/50 AUTHOR: IND TOX LAB ADDRESSEE: DOW COPYEE: DOCUMENT 1875 02/01/63 AUTHOR: DOW ADDRESSEE: BAVER LD COPYEE: DOW L E G A S S E Y DJ ro 05 ro TYPE PAGES ABSTRACT BLEIBERG J TITLE PAGE 267 INDUSTRIALLY ACQUIRED PORPHYRIN (ARCH DERMAT 89(6), 795-797). BRODKIN R HALLEN M REPORT DOW 4 THE POLLUTIONAL EVALUATION OF COMPOUNDS WITH 'RED FLAG' DESIGNATIONS. MAXEY JS ADAMS EM CRI MIDLANDTX WESTERN ILGENFRITZ EM SERCU CL BAKER R DYLEWSKI SW KELLY JA SHANNON ES BATCHELDER TB GRUBE JR NOVAK RG TEAL JL DATA REPORT 21 RESULTS OF 78 WIPE TESTS PERFORMED AT 265 8 636 BUILDINGS AND ON SEVERAL PESTICIDE RELATED COMPONDS. REPORT 4 REPORT ON EXAMINATION OF RABBIT EAR SKIN AND LIVERS. SADEK SE MEMO GEHRING PJ CONFIRMATION OF DOG POISONING FOLLOWING ORAL INGESTION OF 24D AND 245T CTTL. LETTER SHELANSKI HA ROWE VK 3 2JD AND 245T PROVEN NOT TO BE SKIN SENSITIZERS IN PATCH TEST WITH 100 MALES AND 100 FEMALES CTTL. LETTER 7 ROWE VK EXPERIMENT STATION ROWE VK INFORMATION ON DIFFERENT TOXICOLOGICAL STUDIES PERFORMED ON PENTACHLOROPHENOL, 24D, 245T CTTL. ALLEN WW FURMAN FS NUMBER DATE TYPE PAGES DOCUMENT 1876 11/02/62 LETTER AUTHOR: DOM ROME VK ADDRESSEE: EMPLOYERS MUTUAL OF MAUS MULLINS COPYEE: DOM ROME VK GM 2 DOCUMENT 1877 10/26/62 LETTER AUTHOR: EMPLOYERS MUTUAL OF MAUS MULLINS G ADDRESSEE: DOM ROME VK COPYEE: 1 DOCUMENT 1878 03/31/58 AUTHOR: DOM ADDRESSEE: KOHN CM COPYEE:. DOM LETTER 1 ROME VK PROFESSIONAL BLDG ROME VK DOCUMENT 1879 AUTHOR: DOM ADDRESSEE: COON ET COPYEE: DOM BENDALL 06/11/56 TR LETTER ROME VK ROME VK C O U L T E R LL 5 DOCUMENT 1880 00/00/50 AUTHOR: ONTARIO AG COL ADDRESSEE: COPYEE- NEMS SMITH MV 2 DOCUMENT 1881 03/03/53 LETTER AUTHOR: DOM ADDRESSEE: BOURBON COUNTY HOSPITAL COPYEE: DOM ROME VK KINNAIRD BM ROME VK 2 DOCUMENT 1882 12/19/52 AUTHOR: DOM ADDRESSEE USDA COPYEE: SUNDERLAND MM LETTER ROMK VK HARD JC 2 DOCUMENT 1883 12/16/50 AUTHOR: MILLARD CJ ADDRESSEE: COPYEE- REPORT 5 iseb'Ct ro CO CO TITLE PAGE INFORMATION REGUARDING THE TOXICITY OF 24D 8 245T CTTL. 268 KOEHLINGER DG KRAMER CG INFORMATION REQUEST ON THE TOXICITY OF 24D 8 245T TO AID IN THE DEFENSE OF AN INSURANCE CLAIM CTTL. LABORATORY DATA ON 24D AND 245T SHOWED A FEW CASES OF DERMATITIS CTTL. TOXICITY OF 24D TO BEES. BARRONS KC DAVIDSON JH BECKWITH CL MCCOMB JR WEED KILLING SPRAYS VS BEES (CANADIAN BEE JOUR). IDENTIFICATION AND TREATMENT OF INJURIES CAUSED TO PERSONS HANDLING 24D AND 245T CTTL. GAY HH EFFECT OF DOW HERBICIDES ON EYES CTTL. INDIRECT EFFECTS OF HERBICIDES (NORTH CENTERAL WEED CENTERAL CONTROL CONF 501212 TO 501214). NUMBER DATE TYPE PAGES DOCUMENT 1884 07/18/51 LETTER AUTHOR: DON SOUTHMICK L ADDRESSEE: EASTERN STATES FARMERS E HOVEY CL COPYEE: DON ALLEN MM 2 DOCUMENT 1885 AUTHOR: DOM ADDRESSEE: MO ST COPYEE: DOM SMITH 04/17/51 HIGHMAY DEPT HL LETTER ROME VK REAGEL FV BRANCH CB MILLIAMS GJ 2 DOCUMENT 1886 04/02/51 AUTHOR: MO ST HIGHMAY DEPT ADDRESSEE C O U L T E R LL COPYEE; LETTER REAGEL FV DOM 1 DOCUMENT 1887 02/00/50 AUTHOR: MI L L A R D CJ ADDRESSEE COPYEE: REPORT 7 DOCUMENT 1888 12/09/49 AUTHOR: DOM ADDRESSEE: SMITH HL COPYEE: DOM LETTER ROME VK SOUTHMICK L 2 DOCUMENT 1889 AUTHOR: ADDRESSEE COPYEE 09/08/49 CHART 2 DOCUMENT 1890 05/05/49 AUTHOR DOM ADDRESSEE: DEPT OF HEALTH CAN COPYEE: ALLEN MM LETTER 3 ROME VK SUTHERLAND RB FERGUSON RM DOCUMENT 1891 12/14/65 AUTHOR: DOM ADDRESSEE: BILLINGS CE JR COPYEE: DOM LETTER ROME VK OH ST UNIV ROME VK 1 tO 05 TITLE INDIRECT POISONING EFFECT OF 24D SPRAYING C T T L . PAGE 269 BRYANT C ROME VK 24D, 2A5T AND TCA NOT RESPONSIBLE TO SKIN IRRITATIONS CTTL. COULTER LL GAY HH TOXICITY OF 2AD, 2A5T AND TCA IN RELATION TO SKIN IRRITATION CTTL. INDIRECT EFFECTS OF HERBICIDES. TOXICITY OF 2AD * 245T. TOXICOLOGY TESTS CTTL. TOXICITY OF 2AD AND RELATED MATERIALS. REFERENCES FOR ADDITIONAL SOURCES OF DETAILED INFORMATION CTTL. HILLIAMS GJ DISAGREEMENT OF CLAIMS THAT CASUAL EXPOSURE TO 24D OR 245T CAUSED SEVERE BURNS CTTL. G O R D O N HL NUMBER DOCUMENT 1892 AUTHOR: DOM ADDRESSEE: DOM COPYEE: DOM DATE 10/31/58 TYPE PAGES LETTER 1 MULLISON MR MCCOLLISTER DD C O U L T E R LL DOCUMENT 1893 04/09/51 AUTHOR: C O U L T E R LL ADDRESSEE: MO ST HIGHMAY DEPT COPYEE: DOM LETTER DOM REAGEL FV LYNN GE 1 DOCUMENT 1894 AUTHOR: DOM ADDRESSEE: DOM COPYEE: 10/24/67 LETTER 2 OLSON KJ PROCTER & GAMBLE DOCUMENT 1895 11/12/65 AUTHOR: BILLINGS CE JR ADDRESSEE DOM COPYEE: LETTER OH ST UNIV ROME VK 1 DOCUMENT 1896 AUTHOR: DOM ADDRESSEE: DOM COPYEE: DOM 03/22/65 LETTER MOLF MA G O R D O N HL HOLF MA 1 DOCUMENT 1897 AUTHORi DOM ADDRESSEE: DOM COPYEE: DOM 09/08/58 LETTER 2 TATTERSHALL JT ASHHORTH RH TATTERSHALL JT DOCUMENT 1898 07/11/58 AUTHOR: HYMAZ TA ADDRESSEE DOM COPYEE DOM LETTER NATION HA COULTER LL 1 DOCUMENT 1899 04/09/51 AUTHOR: C O U L T E R LL ADDRESSEE MO ST HIGHMAY DEPT COPYEE: DOM LETTER DOM REAGEL FV LYNN GE 1 /geh*ex DOCUMENT 1900 04/02/51 AUTHOR: MO ST HIGHMAY DEPT ADDRESSEE*- C OULTER LL COPYEE: LETTER REAGEL FV DOW 1 4265 TITLE 24D AND 2A5T WEEDKILLERS AS SNAKICIDES SANTAMARIA R SMITH FB TOXICITY OF 2AD AND 2A5T CTTL. PAGE 270 ACNEGENS AND LABORATORY METHODS FOR EVALUATING THEM CTTL. ROWE VK SNYDER FH REQUEST FOR TOXICOLOGICAL RESPONSES TO CASUAL EXPOSURE TO 24D AND 2<*5T CTTL. TOXICOLOGICAL INFORMATION ON 24D AND 245T FOR G.E. OLESON. 24D AND 245T TOXICITY ON SHEEP. FOSTER WH L E T T E R O F J U N E 16 TO DR K.M. AUT E R Y , T H E E F F E C T O F I N S E C T I C I D E S A N D HERBICIDES ON THE RUMEN OF CATTLE. OTIS CE ROWE VK REGARDING REQUEST FOR TOXICITY INFORMATION ON 24D AND 2 4 5 T CTTL. MATERIALS HANDLING HERBICIDES. NUMBER DOCUMENT 1901 AUTHOR: DON ADDRESSEE* DOM COPYEE: DATE 11/09/56 TYPE ROC JONES MP COON RT PAGES 1 DOCUMENT 1902 AUTHOR: DOM ADDRESSEE! DOM COPYEE: DOM 09/03/54 LETTER ROME VK CLOFT HF ROME VK 1 DOCUMENT 1903 06/21/50 AUTHOR: INGALLS ML ADDRESSEE! FENSTERMAKER PE COPYEE: LETTER 1 DOCUMENT 1904 AUTHOR: DOM ADDRESSEE! DOM COPYEE! 06/29/49 LETTER ROME VK SOUTHMICK L 2 DOCUMENT 1905 07/06/48 AUTHOR: MONONGAHEKA POMER ADDRESSEE! AG CHEM SECTION COPYEE: LETTER RUSSELL SS DOM 1 DOCUMENT 1906 AUTHOR: DOM ADDRESSEE DOM COPYEE: 07/14/48 LETTER ROME VK ROEHM LS 1 DOCUMENT 1907 06/26/50 AUTHOR: IND TOX LAB ADDRESSEE DOM COPYEE: LETTER SHELANSKI HA ROME VK 3 DOCUMENT 1908 06/28/50 AUTHOR: KLAUDER JV ADDRESSEE! IND TOX LAB COPYEE: LETTER SHELANSKI HA 1 DOCUMENT 1909 AUTHOR: DOM ADDRESSEE: DOM COPYEE: DOM KELLY 10/19/53 JA LETTER ROME VK COULTER ROME VK LYNN GE LL 1 O 05 05 TITLE TOXIC EFFECTS OF 245T ON TURKEYS CTTL SMITH HL WALLBERG JH 24D, 245T OFF FLAVORS IN MILK. BENDALL F SMITH HL SHEEP MAY HAVE DIED FROM INGESTING 245T CTTL. PAGE 271 TOXICITY OF 245T. VEGATATION CONTROL. DEATH OF CHICKENS FROM SPRAYING BRUSH HITH ESTERON 44 AND 245. REPORT ON PATCH TEST CTTL. PATCH TEST ON COMPOUNDS REPORT CTTL. K9151 AND K12894. BARRONS KC JOHNSON JE NUMBER DOCUMENT 1910 AUTHOR: DOM ADDRESSEE-- NAS COPYEE: DOM DATE 07/21/66 TYPE PAGES LETTER ROME VK HANDS RC LYNN GE 2 DOCUMENT 1911 09/07/49 AUTHOR' DOM ADDRESSEE: FERGUSON RM COPYEE: DOM LETTER ROME VK ATKEY JM 1 DOCUMENT 1912 03/16/49 LETTER AUTHOR: DOM ROWE VK ADDRESSEE: AM MUTUAL LIABILITY INSU THOMPSON EM COPYEE: ALLEN MM 1 DOCUMENT 1913 AUTHOR: DOM ADDRESSEE: COPYEE: DOM 07/24/68 MEMO GE H R I N G PJ GEHRING PJ 1 DOCUMENT 191A 07/26/68 AUTHOR: DOM ADDRESSEE: CUTTING ME COPYEE: DOM LETTER KENAGA EE ROME VK 1 DOCUMENT 1915 08/02/57 AUTHOR: DOM ADDRESSEE AG CHEM SALES COPYEE DOM LETTER WOLF MA BRYANT C ROME VK 2 DOCUMENT 1916 06/25/64 AUTHOR: DOM ADDRESSEE-' D I N M A N 1BD COPYEE: DOM LETTER ROME VK OH ST UNIV ROME VK 2 DOCUMENT 1917 AUTHOR: DOM ADDRESSEE: DOM COPYEE: DOM 09/13/63 REPORT MOLF MA C O U L TE R LL MOLF MA 3 9^a; DOCUMENT 1918 AUTHOR: DOM ADDRESSEE: DOW COPYEE: 03/18/55 LETTER WOLF MA SOUTHWICK L 2 O 05 -v i TITLE INFORMATION ON THE ISO-OCTYL ESTER OF 245T CTTL. PAGE 272 TOXICITY OF 24D ESTERS. CLOSS RC SOUTHWICK L ESTERON A4 AND ESTERON 245 POSE NO HEALTH HAZARDS CTTL. M E M O C O N F I R M I N G D O G 'S C O N D I T I O N W A S C O N S I S T E N T W I T H 2 4 D A N D 245T POISONING CTTL. 245T TOXICITY TO FISH CTTL. TOXICITY OF 24D AND 245T TO TROUT. R E P L Y TO D I N M A N 'S 640 6 1 6 L E T T E R I N Q U I R I N G A B O U T T H E T O X I C I T Y OF 245T CTTL. INFORMATION FOR DR. J.A. SPENCE, STA N D A R D OIL CO. OF CA. TOXICOLOGICAL COMPARISON OF 24D, 245T, AND SILVEX. NUMBER DATE DOCUMENT 1919 04/12/54 AUTHOR: GAY HH ADDRESSEE: PURDUE UNIV COPYEE: TYPE PAGES LETTER 1 VANDEMARK JS DOCUMENT 1920 04/02/54 AUTHOR: ADDRESSEE: COPYEE: DOW PURDUE UNIV DOW WILLIAMS GJ LETTER ROWE VK VANDEMARK JS ROWE VK 1 DOCUMENT 1921 03/24/54 AUTHOR: PURDUE UNIV ADDRESSEE DOW COPYEE: LETTER VANDEMARK JS ROWE VK 1 DOCUMENT 1922 07/27/53 AUTHOR: DOW ADDRESSEE' MARX EE JR COPYEE: DOW SOUTHWICK L LETTER ROWE VK BENDAL TL WILLIAMS GJ 5 DOCUMENT 1923 06/23/53 LETTER 1 AUTHOR' DOW ADDRESSEE: LUCAS TREE EXPERT COPYEE: BENDALL T ROWE VK SICKMAN WL CLOFT HF DOCUMENT 1924 04/17/51 LETTER 2 AUTHOR: ADDRESSEE: COPYEE: DOW MO ST HIGHWAY DOW SMITH HL DEPT ROWE VK REAGEL FV BRANCH CB WILLIAMS GJ DOCUMENT 1925 07/13/50 AUTHOR: OH ST UNIV ADDRESSEE' DOW COPYEE: DOW WILLIAMS GJ LETTER WILLARD CJ SOUTHWICK L ALLEN W 2 b^Zh-a ro 05 -00 TITLE PAGE IN REGARDS TO MAYFIELDS DERMATOSIS REACTION TO 2A5T C T T L . 273 IN REGARDS TO MR MAYFIELDS DERMATITIS ALLEGEDLY DUE TO CONTACT WITH 245T CTTL. GAY HH SMITH HL NEED TREATMENT FOR TOXICOLOGICAL REACTION TO SKIN FROM 2A5T CTTL. TOXICOLOGICAL PROPERTIES OF 245T AND 24D CTTL. KRINER RH SMITH HL EYE CONTACT WITH A 245T SOLUTION REQUIRES IMMEDIATE FLUSHING OF THE EYE AND ADDITIONAL MEDICAL ATTENTION TO MINIMIZE EYE IRRITATION AND ACCELERATE HEALING CTTL. GAY HH SMITH HL SODIUM TCA IS MORE LIKELY TO CAUSE SKIN IRRITATION THAN 2AD OR 245T BECAUSE IT IS USED IN HIGHER CONCENTRATIONS AND IT IS INHERENTLY MORE IRRITATING CTTL. COULTER LL GAY HH 24D USE ON VEGETATION IS DETERMINED NOT TO BE THE CAUSE BEHIND THE DEATH OF GRAZING SHEEP CTTL. DOUST AF ROWE VK NUMBER DATE DOCUMENT 1926 07/24/50 AUTHORi DON ADDRESSEE-' FISCHER PJ COPYEE: SHELL K DOCUMENT 1927 11/28/49 AUTHOR: DOM ADDRESSEE DEE WE COPYEE: ROWE VK DOCUMENT 1928 AUTHOR DOW ADDRESSEE: DOW COPYEE: 06/29/49 DOCUMENT 1929 AUTHOR: DOW ADDRESSEE: DOW COPYEE: DOW 04/28/48 DOCUMENT 1930 AUTHOR: DOW ADDRESSEE: COPYEE: 06/01/55 DOCUMENT 1931 AUTHOR DOW ADDRESSEE COPYEE: 12/21/65 DOCUMENT 1932 AUTHOR: ADDRESSEE COPYEE: 00/00/65 DOCUMENT 1933 AUTHOR: DOW ADDRESSEE: COPYEE: 01/23/69 TYPE PAGES LETTER 2 SOUTHWICK L SOUTH CENTRAL RURAL LETTER SOUTHWICK L USDA 1 LETTER ROWE VK SOUTHWICK L 2 LETTER 2 SOUTHWICK L SISSON HA JR IRISH DD TECH WOLF MA 2 REPORT 5 REPORT 14 REPORT NORRIS JM 16 TITLE PAOE 27A 24D AND 245T SPRAYED VEGETATION DOES NOT INJURIOUS EFFECT WHEN EATEN BY LIVESTOCK CT T L . ELEC LITTLE HAZARD FROM THE USE OF 245T IN PASTURES WHEN USED AS RECOMMENDED CTTL. TESTS REVEAL 245T TO BE LOW IN TOXICITY BUT EVIDENCE DOES NOT SHOW IT TO BE SAFE FOR USE ON FOOD PRODUCTS (TOXICITY OF 245T) CTTL. DETAILS ABOUT VARIOUS HERBICIDES TO MIX FOR EFFECTIVE APPLICATION AND THOSE HERBICIDES NOT TO MIX CTTL. ESTERON 245. CHEMICALS 245T ISOOCTYL ESTER REQUEST FOR SCREENING OR APPLICATION TESTING. TOXICITY OF CHLORINATED PHENOXYALKYL ACIDS TO MAN AND EXPERIMENTAL ANIMALS CTTL. TOXICOLOGICAL PROPERTIES OF TORDON 124V BRUSH KILLER. NUMBER DOCUMENT 1934 AUTHOR: ADDRESSEE: COPYEE: DATE 00/00/68 DOCUMENT 1935 AUTHOR: DOW ADDRESSEE: COPYEE-' 01/17/67 DOCUMENT 1936 01/17/67 AUTHOR DOW ADDRESSEE: GILMAN H COPYEE: DOCUMENT 1937 02/15/67 AUTHOR: ADDRESSEE: COPYEE: DIXON WR DOW MCCOY WJ DOCUMENT 1938 07/01/54 AUTHOR: ADDRESSEE: COPYEE: BUCKLEY WR SUSKIND R DOCUMENT 1939 00/00/68 AUTHOR: CHRISTOFANO EE 1ND BIOTEST LAB ADDRESSEE: COPYEE: 0 DOCUMENT 1940 00/00/66 AUTHOR: BLUMS ZB ADDRESSEE: COPYEE: TYPE MEMO PAGES 1 CHART SILVERSTEIN 1 LETTER 1 SILVERSTEIN LG IA ST UNIV LETTER 2 DOW CORBIN WL PLETCHER DE REPORT 22 KEHOE RA UNIV OF CINCINNATI ABSTRACT FANCHER OE KEPLINGER ML 2 NEWS 17 REPORT CENTRO DERMATOLOGICA s to <r> o S' TITLE T O X I C I T Y ( V O L U M E 1) PAGE 275 FOLLICULITIS RESPONSE OF THE RABBIT EAR TO SINGLE APPLICATION OF TCDD (TC) AND TCDD (TB). TABLE. BRIEF REVIEW OF BIOASSAY RESULTS USING TCDD AND 2378-TETRABR0M0DIBENZ0-P-DI0XIN CTTL. TRICHLOROPHENOL ACCIDENT AT TCC, ST LOUIS, MO, INCIDENTS OF CHLORACNE, AND CLEANUP EFFORTS CTTL. COWELL JH HOLDER BB THE CUTANEOUS AND TOXICOLOGICAL APPRAISAL OF PRODUCTS EVOLVED IN T H E 2<*5T S Y N T H E S I S S U B M I T T E D BY MON, NITRO, WV. KETTERING LAB MON WALKER M INFLUENCE OF DIOXIN ON LIVER FUNCTION IN THE RABBIT. FRAWLEY JP HER SCHOENIG GP C L I N I C A L S T U D I E S O C C U P A T I O N A L A C N E ( M E D I C I N A C U T A N E A 3, 225-232) FED LONDONO F iet'CC, NUMBER DOCUMENT 1941 DATE 00/00/67 AUTHOR C&EN NEWS ADDRESSEE COPYEE DOCUMENT 1942 07/28/67 AUTHOR CHRISTOFANO EE ADDRESSEE DOM COPYEE DOCUMENT 1943 08/10/67 AUTHOR CHRISTOFANO EE ADDRESSEE DOM COPYEE DOCUMENT 1944 00/00/48 AUTHOR FAREMELL ED ADDRESSEE COPYEE DOCUMENT 1945 06/02/49 AUTHOR ALLEN MM ADDRESSEE DOM COPYEE IRISH DD DOCUMENT 1946 AUTHOR DOM ADDRESSEE COPYEE 03/09/49 DOCUMENT 1947 08/29/50 AUTHOR ADDRESSEE COPYEE DOM DOM BRITTON JM KAGY JF DOCUMENT 1948 AUTHOR: DOM ADDRESSEE COrYEE 03/09/49 ro TYPE ABSTRACT NEWS PAGES 1 LETTER HER ROME VK 1 LETTER HER ROME VK 1 REPORT GRISBY BH 14 LETTER DOM BALLMAN DK 5 TEST 8 MCCOLLISTER DD REPORT ROME VK ALLEN MM DOSSER RC LYNN GE 2 TEST 24 MCCOLLISTER DD TITLE PAGE SEARCH FOR CHICK EDEMA FACTOR (1356. CHICK EDEMA FACTOR BREAKTHROUGH)(C&EN 45(5), 10KBIBRA INFO BULLETIN 6, 97). 276 CHICK EDEMA STUDIES WITH TCDD CTTL. SOURCES OF CHLORINATED DIBENZODIOXIN IN CHICKEN FEED CTTL. SOME EFFECTS OF HERBICIDES ON GRAZING LIVESTOCK. AUTHORIZATION FOR THE STUDY OF POSSIBLE TOXICITY OF DOW WEEDS AND GRASS KILLERS TO FARM ANIMALS TO BE CONDUCTED BY MICHIGAN STATE EXPERIMENT STATION. MIXED AMYL ESTER OF 245T REQUEST FOR BIOLOGICAL TEST. SPENCER HC RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON THE MIXED AMYL ESTER OF 245T. SPENCER HC BARRONS KC BRITTON DIV DUTTON WC IRISH DD ISOPROPYL ESTER OF 245T REQUEST FOR BIOLOGICAL TEST. SPENCER HC 8ieh-<z NUMBER DATE DOCUMENT 1949 08/28/50 AUTHOR: DOM ADDRESSEES DOW DOSSER RC LYNN GE COPYEEs DOCUMENT 1950 AUTHORS DOW ADDRESSEE COPYEEs 01/19/48 DOCUMENT 1951 AUTHORS 1 BLP ADDRESSEE: COPYEEs 06/26/46 DOCUMENT 1952 AUTHOR: ADDRESSEE COPYEEs 10/02/50 DOCUMENT 1953 AUTHOR: DOW ADDRESSEE DOW COPYEEs 01/06/53 DOCUMENT 1954 03/26/64 AUTHOR: HOYLE HR ADDRESSEE: COPYEEs DOCUMENT 1955 04/04/64 AUTHOR: DOW TAYLOR ML ADDRESSEE: COPYEEs DOW GORDON HL HOLDMAN GE KOERKER FW NORTON TR WRIGHT N ro TYPE PAGES DISTRB REPORT ROME VK ALLEN WW DUTTON WC 4 REPORT ROWE VK 3 TEST 1 HAS 2 REPORT 1 LETTER 2 ROWE VK SUNDERLAND WW REPORT OLSON KJ 15 DISTRB REPORT HOLDEMAN GE 4 BOUNDY RH GREENE LM JONES GD LUCE EN PITMAN MOORE TITLE PAGE RESULTS OF TOXICOLOGICAL TESTS ON 245T ISOPROPYL ESTER. SPENCER HC BARRONS KC IRISH DD BRITTON JW KAGY JF 277 RESULTS OF ACUTE ORAL TESTS ON METHYL ESTER OF 2A5T ETHYL SALICYLATE 8-HYDROXY QUINOLINE A-BROMONAPHTHALENE. REQUEST FOR BIOLOGICAL TEST (BIOCHEM FILE T2514-11). I JB 245T. 24D AND 2A5T LABELS. 2A5T DATA SHEET OF PROPERTIES, HEALTH HAZARDS, AND PRECAUTIONS FOR SAFE HANDLING OF MATERIALS. OYEN F TAYLOR ML RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON 245T. OLSON KJ OYEN F ELSHERE D HAKE CL KAGY JF LYNN GE SHRADER SA EPSTEIN J HART A KILIAN DJ MCINTYRE HH WILSON AW NUMBER DOCUMENT 1956 AUTHOR: DON ADDRESSEE: DON COPYEE: DATE 07/06/59 TYPE 1PAGES LETTER WOLF MA COULTER LL 2 DOCUMENT 1957 12/21/64 AUTHOR: KLIGMAN AM ADDRESSEE DON COPYEE: REPORT .UNTV OF PA ROWE VK 4 DOCUMENT 1958 03/15/65 LETTER 4 AUTHOR? DOW ADDRESSEE: DOW COPYEE: DOW HOLDER BB SILVERSTEIN LG REPORT OHARE CP GORDON HL OHARE CP HOYLE HR STEWART RD DOCUMENT 1959 AUTHOR: DOW ADDRESSEE: COPYEE: 09/29/65 CHART OHARE C 1 DOCUMENT 1960 AUTHOR: DOW ADDRESSEE: TIMM W COPYEE: 02/25/65 LETTER 1 DOCUMENT 1961 00/00/67 AUTHOR: CORNELL ADDRESSEE: COPYEE: REPORT LISK DJ 4 DOCUMENT 1962 04/10/68 LETTER AUTHOR: KRAUSCHE KK NACA ADDRESSEE: NACA IND TASK FORCE ON P COPYEE: 1 O -a CO TITLE RABBIT TOX TEST SUMMARY REPORT CTTL. PAGE 278 PATHOGENESIS OF CHEMICALLY INDUCED ACNE. THE FORMATION OF FOLLICULITIS IN THE RABBIT EAR FOLLOWING A SINGLE SUBCUTANEOUS INJECTION OF SYMMETRICAL TETRACHLORODIBENZODIOXIN IN BENZENE. OLSON KJ ADAMS EM KRAMER CG GAY HH ROWE VK TOXICOLOGICAL TEST OF APPLIED VEON BRUSH KILLER, VEON 245T, TORDON 101, AND WEEDAR 245T AMINE CTTL. STATUS OF DIRECT ESTER PROCESS. FATE OF ATRAZINE, KURON, SILVEX, AND 245T IN THE DAIRY COW (JOUR DAIRY SCIENCE W 1 , 1267-1270K T A 5 0 .01 .P4HPP8F0669). S T J O H N LE JR WAGNER DG FDA LETTER ON PESTICIDE PETITION REQUESTING TOLERANCES FOR RESIDUES OF 265T. NUMBER DOCUMENT 1963 DATE 02/21/65 AUTHOR! KLINGMAN DL ADDRESSEE COPYEE: DOCUMENT 1964 10/00/54 AUTHOR! DOM ADDRESSEE COPYEE: DOCUMENT 1965 10/00/54 TYPE PRESENT PAGES 10 REPORT USDA ARS REPORT HYMAS TA 10 REPORT 9 AUTHOR: DOM ADDRESSEE: COPYEE: HYMAS TA DOCUMENT 1966 02/00/50 AUTHOR: AG EXP STATION MI ADDRESSEE: COPYEE REPORT FARMELL ED 9 DOCUMENT 1967 00/00/66 AUTHOR: ENVIRONMENT ADDRESSEE COPYEE: NEMS 1 DOCUMENT 1968 00/00/66 AUTHOR: SUND JM ADDRESSEE: COPYEE: REPORT 2 DOCUMENT 1969 00/00/68 AUTHOR! KLINE JR ADDRESSEE: COPYEE! REPORT 8 U.S. ATOMIC ENERGY ro nU TITLE PAGE 279 RESEARCH ON CONTROL OF WEEDS AND BRUSH ON RANGELAND (TX AG AVIATION CONF AND SHORT COURSE ON PEST CONTROL 650221 TO 650223HTORDON 101 MIXTURE TI COMPILATION PA2.08.S6). SUMMARY OF TOXICOLOGICAL INFORMATION ON 24D AND 245T TYPE HERBICIDES AND AN EVALUATION OF THE HAZARDS TO LIVESTOCK ASSOCIATED WITH THEIR USE (AM JOUR OF VETERINARY RES 15(57), 622-629). ROWE VK SUMMARY OF TOXICOLOGICAL INFORMATION ON 24D AND 245T TYPE HERBICIDES AND AN EVALUATION OF THE HAZARDS TO LIVESTOCK ASSOCIATED WITH THEIR USE(AM JOUR OF VETERINARY RES 15(57), 622-629HDA 1.00SL). ROWE VK SOME EFFECTS OF HERBICIDES ON PASTURE AND ON GRAZING LIVESTOCKIMI AG EXP STATION QUARTERLY BULLETIN 32(3), 378-385) (DA 1.00SL). GRIGSBY BH DIOXIN IN 245T MAY CAUSE LIVER CANCER AND COURT ORDERS EPA TO MAKE DECISION ON BAN OF 245T IN RICE (ENVIRONMENT 14(7), 24) CTTL. MYSTERY OF ABORTIONS IN CATTLE SOLVED WITH HERBICIDES. TESTIMONY ON USE OF THE HERBICIDE 245T FOR VEGETATION MANAGEMENT IN COOK TRANSMISSION CORRIDORS. COMM NUMBER DATE DOCUMENT 1970 07/00/59 AUTHOR: SUND JM ADDRESSEE COPYEE: BARRONS KC GEHRING P TYPE PAGES REPORT 4 WI AG EXP STATN BLAIR E GORING C DOCUMENT 1971 00/00/69 REPORT AUTHOR: MONKS WOOD EXP STATION E WAY JM ADDRESSEE: COPYEE: 26 DOCUMENT 1972 06/00/69 AUTHOR: ADDRESSEE: COPYEE: BATES RR HART ER MITCHELL I PETRUCELLI L REPORT 14 FALK HL INNES JRM NATIONAL CANCER INST ULLAND BM DOCUMENT 1973 00/00/11 AUTHOR: DOW SPARSCHU GL ADDRESSEE: COPYEE: REPORT DUNN FL 24 DOCUMENT 1974 00/00/68 REPORT 3 AUTHOR NEWTON M ADDRESSEE COPYEE: NORRIS LA DOCUMENT 1975 AUTHOR: ADDRESSEE COPYEE: 00/00/69 REPORT 2 DOCUMENT 1976 04/16/68 AUTHOR: HEW ADDRESSEE DUNN CL COPYEE: USDA ARS LETTER 2 STOKES H NACA IND TASK FORCE TITLE PAGE 280 CONTROL WEEDS TO PREVENT LOWLAND ABORTION IN CATTLE (DOWN TO EARTH 10-13, 1959). DAVIDSON J WRIGHT MJ DONALDS J TOXICITY AND HAZARDS TO MAN, DOMESTIC ANIMALS, AND WILDLIFE FROM SOME COMMONLY USED AUXIN HERBICIDES (RESIDUE REVIEWS 26, 37-62). BIOASSAY OF PESTICIDES AND INDUSTRIAL CHEMICALS FOR TUMORIGENICITY IN MICE PRELIMINARY NOTE (JOUR OF THE CANCER INST 92(6), 1101-1119). FISHBE1N L GART JJ KLEIN M LITTON INDUSTRIES PALLOTA AJ PETERS J VALERIO MG THE EFFECTS OF VARIOUS DOSES OF TCDD ADMINISTERED WITH 295T ON RAT FETAL DEVELOPMENT. LISOWE RW ROWE VK HERBICIDE RESIDUES IN BLACKTAIL DEER FROM FORESTS TREATED WITH 295T AND ATRAZINE (PROCEEDINGS FROM SOUTHERN SOCIETY OF WEED SCIENCE 680000). OR ST UNIV 295T, 2-ETHYLEXYL ESTER. PESTICIDE PETITION 8F0675 REQUESTING TOLERANCES FOR RESIDUES OF HERBICIDE SILVEX CTTL. NUMBER DATE TYPE DOCUMENT 1977 04/18/68 LETTER AUTHOR KRAUSCHE KK NACA ADDRESSEE: MEMBERS OF IND TASK FORC COPYEE: PAGES 2 DOCUMENT 1978 04/08/68 AUTHOR: BAKER DM JR ADDRESSEE: DUNN CL COPYEE: USDA ARS LETTER 2 HEM NACA IND TASK FORCE DOCUMENT 1979 AUTHOR: DOM ADDRESSEE! COPYEE: 00/00/50 REPORT 5 MCCOLLISTER DD DOCUMENT 1980 00/00/50 AUTHOR: DRILL VA ADDRESSEE: COPYEE: REPORT 12 HAYNE UNIV COL OF MEI DOCUMENT 1981 AUTHOR: DOM ADDRESSEE: COPYEE: 08/00/50 REPORT 5 DOCUMENT 1982 AUTHOR: DOM ADDRESSEE: COPYEE: 07/00/63 MEMO 1 DOCUMENT 1983 AUTHOR: DOM ADDRESSEE: DOM COPYEE: DOM 07/20/62 LETTER ROME VK MIFFEN EE COULTER LL 3 DOCUMENT 1984 AUTHOR: DOM ADDRESSEE: DOM COPYEE: DOM 05/13/60 LETTER HARDY JL JOSEPHS MJ FALSEY WP 2 r-zg/r^r: ro os TITLE PAGE 281 FDA LETTERS ON PESTICIDE PETITIONS REQUESTING TOLERANCES FOR RESIDUES OF 24D, SILVEX, MCPA, AND 245T. PESTICIDE PETITION 8F0669 REQUESTING TOLERANCES FOR RESIDUES OF HERBICIDE 245T CTTL. THE ACUTE ORAL TOXICITY OF 245T TO RATS, MICE, GUINEA PIGS AND CHICKS. ROWE VK SPENCER HC ACUTE AND SUBACUTE ORAL TOXICITY OF 2A5T FOR DOGS. DICI RESULTS OF TOXICOLOGICAL TESTS ON 2A5T. A COMPILATION OF TOXICOLOGICAL INFORMATION REGARDING 245T. TOXICOLOGICAL INFORMATION CONCERNING KUROSAL SL AND KUROSAL G. LYNN GE TOXICITY OF M-1845 CPOTASSIUM D-(245-TRICHL0R0PHEN0XY)-PR0PI0NATE TO LAKE EMERALD SHINERS. KENAGA EE RITTY PM NUMBER DOCUMENT 1985 AUTHOR: DOH ADDRESSEE COPYE: DATE 12/00/64 DOCUMENT 1986 AUTHOR: DOH ADDRESSEE: COPYEE: 12/00/64 DOCUMENT 1987 AUTHOR: DOH ADDRESSEE: DOH COPYEE: DOH 10/21/53 DOCUMENT 1988 11/21/60 AUTHOR: RAYNOR RN ADDRESSEE DOH COPYEE: DOH DOCUMENT 1989 06/12/62 AUTHOR: LOHE JI ADDRESSEE: DOH COPYEE: DOCUMENT 1990 06/21/68 AUTHOR: DAVIDSON JH ADDRESSEE DOH COPYEE: DOH RIDNER JM DOCUMENT 1991 10/16/68 AUTHOR: DAVIDSON JH ADDRESSEE DOH COPYEE: DOH DOCUMENT 1992 10/18/68 AUTHOR: DOH ADDRESSEE DOH COPYEE: DOH HELTON JD TYPE REPORT REPORT PAGES 13 8 LETTER 2 HINSTON AH JR DRESSEL GF BRITTON JH LETTER HARREN LE COULTER LL 2 LETTER SDI RITTY PM 1 LETTER DOH FERGUSON H BRYANT CA HATSON JA 1 LETTER 1 DOH MCCOLLISTER DD HANSON RG LETTER HAMMER OH DAVIDSON JH HANSON RG HILTSE MG 2 >1 Id to <1 TITLE PAGE 282 ACUTE AND SEMICHRONIC TOXICITY OF "SILVEX" TO LABORATORY RATS. COMPILATION OF INFORMATION CONCERNING THE TOXICOLOGY AND PERSISTENCE OF SILVEX (2-(2A5-TRICHL0R0PHEN0XY) PROPIONIC ACID). MINNOW TOXICITY OF MATERIAL USED IN WEED KILLERS. HARLOW IF ROWE VK TOXICITY DATA ON 24D AND RELATED MATERIALS CTTL. RITTY PM SWEZEY AW REQUEST FOR INFORMATION ON FISH TOXICOLOGY STUDIES DONE BY DOW, RESULTS OF USDI TESTS CTTL. ENCLOSES SEVERAL PIECES OF LITERATURE DEALING WITH TOXICOLOGICAL ASPECTS OF SILVEX. HAMMER OH WILTSE MG MCCOY WJ DIA REGISTRATION FOR SILVEX. WELTON JD WILTSE MG SILVEX TOXICITY TO FISH INQUIRY BY DIA. I CJS KENAGA EE MCCOLLISTER DD NUMBER DATE DOCUMENT 1993 12/23/69 AUTHOR: DOWNARD GM ADDRESSEE: DOM COPYEE: TYPE PAGES LETTER 1 USDA ARS SACHS SB DOCUMENT 1999 12/29/66 AUTHOR: DON ADDRESSEE: DOM MCCOY MJ COPYEE: MEMO REPORT LENG ML BARRONS KC WATSON AJ 7 DOCUMENT 1995 03/26/60 AUTHOR: DOM ADDRESSEE COPYEE: DOW I GEL I UL I RWC RITTY PM ABSTRACT 1 GETZENDANER ME BARRON KC I JFK I MJJ I TRN DOCUMENT 1996 03/18/69 LETTER 1 AUTHOR: DOM ADDRESSEE DUNN CL COPYEE: DOM LYNN GE MCCOLLISTER DD HER BLAIR EH MOSS RD DOCUMENT 1997 03/09/69 AUTHOR: KLINGMAN DL ADDRESSEE DUNN CL COPYEE: DANIELSON LL LETTER USDA ARS HER RADELEFF R DOCUMENT 1998 09/26/68 MINUTES AUTHOR: NACA IND TASK FORCE ON P ADDRESSEE: COPYEE: 1 DOCUMENT 1999 11/27/67 AUTHOR: DUNN CL ADDRESSEE: HAYS H COPYEE'- ANDERSON RJ LETTER HER USDA DANIELSON 2 TITLE PAGE 283 KURON BRUSH KILLER REGISTRATION NUMBER 464-162 WITH LETTER OF 641110. KURON BRUSH KILLER NO RESIDUE REGISTRATIONS. GETZENDANER ME WILTSE MG LYNN GE A RESIDUE STUDY OF SILVEX IN FISH LIVING IN KURON CONTAINING WATER (REPORT GH-490). BLAIR EH I JS I OHH JOHNSON JE I CWH I JWV I RPP LYNN GE THOUGTS ON THE PROTOCOL FOR THE STUDY IN CATTLE AND SHEEP TO SUPPORT THE RANGELAND AND PASTURE GRASS USE OF PHENOXY HERBICIDES CTTL. NACA BYRD BC DAVIDSON JH FEEDING TRIAL OF HERBICIDE TREATED GRASSES TO TEST ANAIMALS CTTL. USDA INDUSTRY TASK FORCE MEETING OF 680926 CTTL. NACA REQUESTS EXTENSION ON PHENOXY REGISTRATION CTTL. IRVING GW USDA ARS NUMBER DATE DOCUMENT 2000 11/27/67 AUTHOR: DUNN CL ADDRESSEE: HAYS H COPYEE: ANDERSON1 RJ TYPE PAGES LETTER HER USDA DANIELSON LL 2 DOCUMENT 2001 10/29/68 AUTHOR: DUNN CL ADDRESSEE: HAYS H COPYEE: USDA ARS LETTER HER USDA ARS DANIELSON LL 3 DOCUMENT 2002 01/09/69 LETTER MINUTES AUTHOR: DUNN CL NACA ADDRESSEE: NACA IND TASK FORCE ON P COPYEE: 2 DOCUMENT 2003 AUTHOR: ADDRESSEE COPYEE: 01/28/69 MINUTES 3 DOCUMENT 2004 03/04/69 AUTHOR: KLINGMAN DL ADDRESSEE DUNN CL COPYEE: DANIELSON LL LETTER USDA HER RADELEFF R 2 DOCUMENT 2005 03/11/69 AUTHOR: DOM ADDRESSEE DOM COPYEE: DOM MOSS RD LETTER 3 GETZENDANER ME MCCOLLISTER DD BYRD BC DOCUMENT 2006 01/20/69 AUTHOR: DOM ADDRESSEE: LISK DL COPYEE: DOM LETTER 2 LENG ML NY ST COL OF AG MCCOLLISTER DD DOCUMENT 2007 AUTHOR: DOM ADDRESSEE: HEM COPYEE: DOM 06/09/55 LETTER LYNN GE RANKIN MB DREESSEN J 2 co CO TITLE PAGE NACA REQUESTS EXTENSION OF PHENOXY REGISTRATION CTTL. NACA IRVING GW USDA ARS 284 NACA ASKS FOR RESIDUE TOLERANCES FOR MEAT INSTEAD OF GRASS CTTL. NACA TASK FORCE MEETING, WASHINGTON 690128. ITFPHT MEETING OF 690128 CTTL. DISCUSSION OF PROPOSED FEEDING TESTS OF PHENOXIES ON LIVESTOCK CTTL. USDA ARS MEAT STUDY FOR PHENOXY HERBICIDES. DAVIDSON JH LYNN GE REQUEST DATA TO SUPPORT TOLERANCE PETITIONS FOR 24D, 245T, MCPA AND SILVEX FOR TREATMENT OF GRASSES CTTL. RESIDUES OF 24D, 245T, AND MCP ON PASTURE AND RANGE FORAGE RESULTING FROM WEEDKILLING APPLICATIONS CTTL. KOEHLER HC SUNDERLAND WW NUMBER DATE lOCUMENT 2008 10/13/58 iUTHOR* DREESSEN J ADRESSEE NACA :OPYEE* )OCUMENT 2009 03/26/65 AUTHOR ! AG EXTEN SER ID \DDRESSEE* 'OPYEE: JOCUMENT 2010 AUTHOR* DOW \DDRESSEE! DOW :OPYEE: 04/02/65 DOCUMENT 2011 AUTHOR* DOW ADDRESSEE! :0PYEEs 09/27/67 DOCUMENT 2012 08/00/68 AUTHOR* COURTNEY KD ADDRESSEE* COPYEE: DOCUMENT 2013 11/27/61 AUTHOR* ADDRESSEE COPYEE* DOW DOW ELSHERE D HART A LUCE EN SHRADER SA DOCUMENT 201A AUTHOR* DOW ADDRESSEE* DOW COPYEE* DOW 12/06/66 DOCUMENT 2015 AUTHOR* DOW ADDRESSEE* COPYEE* <n ro G* Q O , o 07/00/68 TYPE PAGES LETTER 5 NACA HITCHNER NEWS UNIV OF ID 1 LETTER 1 SUNDERLAND WW LYNN GE REPORT LENG ML 1 REPORT 7 REPORT 10 GREENHOE NC BARRONS KC FALKENSTEIN WJ JONES GD LYNN GE TISDALE WL LETTER 1 GETZENDANER ME BROWN FG DAVIDSON JH REPORT LENG ML 58 TITLE PAGE 285 JULY 28 CONFERENCE WITH USDA AND FDA ON THE USE OF 24D AND 245T ON GRAZING LANDS. NEW RULING ON 24DTHE WEED FIGHTER NO. 43). 24D ON PASTURES. INTERPRETATION OF DATA ON TOXICITY OF 24D FOR LIVESTOCK. 245T IN THE RAT EXCRETION PATTERN SERUM LEVELS PLACENTAL TRANSPORT AND METABOLISM (PESTICIDES SYMPOSIA 277-283HINTERAMERICAN CONFERENCES ON TOXICOLOGY AND OCCUPATIONAL MEDICINE MIAMI FL). RESULTS OF 90 DAY DIETARY FEEDING STUDIES ON DOWANOL 97B ESTER 245-T IN RATS. MCCOLLISTER DD BOUNDY RH GAY HH KAGY JF MCINTYRE HH WRIGHT N COLBY RW GREENE LM KILIAN DJ PERKINS RP TCDD TOXICITY. LENG ML MCCOLLISTER DD REVIEW ON THE METABOLISM OF PHENOXY COMPOUNDS IN PLANTS & ANIMALS NUMBER DOCUMENT 2016 AUTHOR: DOW ADDRESSEE COPYEE: DATE 06/03/68 DOCUMENT 2017 05/24/68 AUTHOR DOW ADDRESSEE CORNELL COPYEE! DOW DOCUMENT 2018 AUTHOR: DOW ADDRESSEE COPYEE: 08/29/68 DOCUMENT 2019 AUTHOR DOW ADDRESSEE COPYEE: 07/00/68 DOCUMENT 2020 AUTHOR*' DOW ADDRESSEE'* COPYEE: 07/00/68 DOCUMENT 2021 AUTHOR: DOW ADDRESSEE COPYEE: 07/00/68 DOCUMENT 2022 08/00/68 TYPE TELECON LENO ML PAGES 1 LETTER 2 LENG ML STJOHN LE JR MCCOLLISTER DD MEMO LENG ML 1 REPORT LENG ML 4 REPORT LENG ML 4 REPORT LENG ML 31 CHART 5 AUTHOR COURTNEY KD ADDRESSEE*' COPYEE: *3 -C TO GO NJ PRESENT REPORT TITLE PAGE 286 PHONE CALL FROM DON LISK STATING THE 306 MG HE RECOVERED WAS IN TERM OF SILVEX, THEREFORE HE RECOVERED 1021 PERCENT OF THE ESTER. LETTER REQUESTING FURTHER INFORMATION TO CLARIFY ARTICLE ON FATE OF KURON IN THE DAIRY COW CTTL. CHANGES IN MANUSCRIPT ON METABOLISM OF PHENOXY COMPOUNDS. REVIEW ON THE METABOLISM OF PHENOXY COMPOUNDS IN PLANTS AND ANIMALS. 3. RECENT RESIDUE STUDIES BY NEWER METHODS. REVIEW ON THE METABOLISM OF PHENOXY COMPOUNDS IN PLANTS AND ANIMALS. 2. METABOLISM IN ANIMALS. REVIEW ON THE METABOLISM OF PHENOXY COMPOUNDS IN PLANTS AND ANIMALS. 1. METABOLISM IN PLANTS. PESTICIDES SYMPOSIA 245T IN THE RAT EXCRETION PATTERN, SERUM LEVELS, PLACENTAL TRANSPORT, AND METABOLISM (COLLECTION OF PAPERS PRESENTED AT INTER-AMERICAN CONFERENCES ON TOXICOLOGY AND OCCUPATIONAL MEDICINE UNIVERSITY OF MIAMI SCHOOL OF MEDICINE, MIAMI, FL) (SIXTH CONFERENCE 680800) (SEVENTH CONFERENCE 700800). NUMBER DOCUMENT 2023 AUTHOR DOM ADDRESSEE COPYEE DATE 12/00/68 DOCUMENT 2024 03/04/69 AUTHOR KLINGMAN DL ADDRESSEE DUNN CL COPYEE DANIELSON LL DOCUMENT 2025 AUTHOR ADDRESSEE COPYEE 06/00/69 DOCUMENT 2026 09/00/68 AUTHOR BYRD BC KENAGA EE ADDRESSEE COPYEE DOCUMENT 2027 AUTHOR DOM ADDRESSEE COPYEE 06/28/67 DOCUMENT 2028 06/29/54 AUTHOR DOM ADDRESSEE COPYEE DOCUMENT 2029 11/13/58 AUTHOR ADDRESSEE COPYEE DOM DOM DIETER CE KAGY JF NORTON TR VANVOLKENBURG JM TYPE REPORT LENG ML PAGES 1 LETTER US DA HERCULES RADELEFF R REPORT 2 4 REPORT 19 DAVIDSON JH LENG ML DATA TINKER BP 12 REPORT 7 MCCOLLISTER DD REPORT 15 MATSON AJ BARRONS KC HAMMER OH LAWRENCE JM PERKINS RP WARREN LE Vu vi fO 00 IO TITLE PAGE 287 DEFICIENCIES IN RESIDUE DATA FOR SILVEX LISTED BY REVIEWERS (1) AND (2 ). POSSIBLE CHANGE IN FEEDING TEST OF PGBE ESTERS OF SILVEX DUE JO THE DIFFERENCE IN MOISTURE CONTENT OF THE HAY CTTL PROTOCOL FOR PHENOXY HERBICIDE ANIMAL FEEDING STUDY. A CRITIQUE OF PICLORAM IN VIETNAM (SCIENTIST AND CITIZEN). DOW HANSEN JC LD50 TCDD TOXICITY STUDIES ON RATS CTTL. RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON ALPHA-(245-TRICHL0R0PHEN0XY) PROPIONIC ACID (MONO, DI, TRIPROPYLENE GLYCOL BUTYL ETHER (B)) ESTER (T25.14-184-1). OYEN F A FIELD EVALUATION OF SEVERAL EXPERIMENTAL EQUATIC HERBICIDES. SUPPLEMENT TO SH-REPORT 391 (SH-393). BLAIR EH HANSON RG LIPPIE LJ SPALDING J COLBY RW JOHNSON JE LYNN GE SWEZEY AW NUMBER DOCUMENT 2030 DATE 10/00/54 AUTHOR DOW ADDRESSEE COPYEE DOCUMENT 2031 00/00/61 AUTHOR UDUALL SL ADDRESSEE COPYEE DOCUMENT 2032 00/00/62 AUTHOR: HUGHES JS ADDRESSEE COPYEE DOCUMENT 2033 03/07/60 AUTHOR DOW ADDRESSEE DOW COPYEE DOW JOSEPHS MJ DOCUMENT 2034 04/16/62 AUTHOR DAVIS JT ADDRESSEE COPYEE DOCUMENT 2035 00/00/64 AUTHOR CORNELL UNIV ADDRESSEE COPYEE DOCUMENT 2036 03/08/63 AUTHOR ADDRESSEE COPYEE <0 BRISCOE JR DOW JARVIS AE SHEA PJ WILTSE MG 3W TYPE REPORT PAGES 8 HYMAS TA TITLE PAo*. 288 SUMMARY OF TOXICOLOGICAL INFORMATION OF 24D AND 245T TYPE HERBICIDES AND AN EVALUATION OF THE HAZARDS TO LIVESTOCK ASSOCIATED WITH THEIR USE (AMERICAN JOURNAL OF VETERINARY RESEARCH 15(57), 622-629) ROWE'v K CHART 8 PESTICIDE WILDLIFE STUDIES A REVIEWOF FISH AND WILDLIFE SERVICE INVESTIGATIONS DURING 610000 AND 620000. REPORT US DEPT OF THE INTERIOR REPORT 2 TOXICITY TO FISH OF DIFFERENT FORMULATIONS OF 245T, 2-(24-DP) AND SILVEX. LA WILDLIFE & FISHERIES LETTER REPORT WINSTON AW JR RITTY PM COULTER LL LYNN GE REPORT HUGHES JS 4 FURTHER STUDY ON THE FISH TOXICITY OF AQUATIC WEED KILLER MATERIALS. DOSSER RC TRUCHELUT GB JOHNSON JE VANVALKENBURG JW VARIATIONS IN TOXICITY TO BLUEGILL SUNFISH OF PHENOXY HERBICIDES (WEEDS 11, 50-53). LA WILD LIFE 8 FISHERIES REPORT LISK DJ FATE OF ATRAZINE, KURON, SILVEX, AND 245T IN THE DAIRY COW (JOURNAL OF DAIRY SCIENCE, 1267-1270). STJOHN LE JR WAGNER DG ABSTRACT DOW CHENOWETH MB JOHNSON JE STOCK B A PHARMACOTOXICOLOGIC PROFILE OF PROPIONIC ACID 2-(245-TRICHLOROPHENOXY) (K39291). WARREN LE FLETCHER RO LYNN GE SWEZEY A HINMAN CW RITTY PM TOMITA M o&eb- NUMBER DOCUMENT 2037 AUTHOR: DOW ADDRESSEE: COPYEE DATE 05/28/59 DOCUMENT 2038 AUTHOR DOW ADDRESSEE COPYEE DOW 01/17/62 DOCUMENT 2039 04/15/63 AUTHOR: DOW ADDRESSEE: COPYEE: DOW BROWN R GREENE LM KILIAN DJ MULLISON WR SHRADER SA DOCUMENT 2040 04/08/65 AUTHOR: BROWN MT ADDRESSEE COPYEE: DOCUMENT 2041 06/06/68 AUTHOR: LISK DJ ADDRESSEE DOW COPYEE: DOCUMENT 2042 00/00/66 AUTHOR: BOWERS JB ADDRESSEE: COPYEE DOCUMENT 2043 00/00/66 AUTHOR: MENZIE CM ^ADDRESSEE' COPY||: lO GO 4^ TYPE REPORT PAGES 2 TECH OLSEN KJ LYNN GE REPORT OLSON KJ OLSON KJ ELSHERE D HART A LUCE EN NASH HA WILSON AW CHART REPORT DOW 4 2 50 LETTER 1 NY STATE COL OF AG LENG ML REPORT CROSY DG A REPORT 9 TITLE PAGE 289 KURON TOXICOLOGICAL INFORMATION AND SUGGESTIONS REGARDING TREATMENT FOR PERSONS SWALLOWING KURON. RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON AGRICULTURAL CHEMICAL FORMULATION M-2121 CONTAINING 50 PERCENT SILVEX EQUIVALENT. OYEN F RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON AGRICULTURAL CHEMICAL FORMULATION M-2303 (CONTAINS DISODIUM ENDOTHAL AND POTASSIUM SALT OF SILVEX ON ATTACLAY). OYEN F BARRONS KC FALKENSTEIN WJ JONES GD LYNN GE NORTON TR WILTSIE M BOUNDY RH GAYHH KAGY JF MCINTYRE HH SCOLES G WRIGHT N RESULTS OF A TWO YEAR DIETARY FEEDING STUDY IN DOGS OF KUROSAL SL (POTASSIUM SALT OF SILVEX). MCCOLLISTER DD ACKNOWLEDGEMENT OF CORRECTIONS NEEDED IN COW FEEDING STUDY CTTL. DETERMINATION OF 24D RESIDUES IN ANIMAL PRODUCTS (BULLETIN OF ENV CONTAMINATION AND TOXICOLOGY 1(3), 104-107). UC DAVIS METABOLISM OF PESTICIDES (USDI FISH AND WILDLIFE SERVICE BUREAU OF SPORT FISHERIES AND WILDLIFE SPECIAL SCIENTIFIC REPORT WILDLIFE 96, 61-69). NUMBER DOCUMENT 2044 AUTHOR: ADDRESSEE COPYEE DATE 00/00/68 DOCUMENT 2045 01/00/53 AUTHOR DRILL VA ADDRESSEE COPYEE DOCUMENT 2046 00/00/69 AUTHOR BARRONS KC UNIV MT ADDRESSEE COPYEE DOCUMENT 2047 07/13/50 AUTHORS BEGIN LE ADDRESSEE COPYEE DOW THURBER WS DOCUMENT 2048 00/00/54 AUTHOR DOW ADDRESSEE COPYEE DOCUMENT 2049 11/29/60 AUTHOR DOW ADDRESSEE COPYEE DOCUMENT 2050 10/00/54 AUTHOR DOW ADDRESSEE COPYEE HYMAS TA w ro JS oo or TYPE REPORT PAGES 10 REPORT HIRATZKA T 8 LETTER REPORT CHESSIN M WILLIS EO 1 REPORT 40 BERHENKE LF DANKERT LJ REPORT HYMAS TA 4 PRESENT REPORT RITTY PM 5 REPORT ROWE VK 4 TITLE PAGE 290 REVIEW ON THE METABOLISM OF PHENOXY COMPOUNDS IN PLANTS AND ANIMALS. TOXICITY OF 29D AND 295T. A REPORT ON THEIR ACUTE AND CHRONIC TOXICITY IN DOGS CAMA ARCHIVES OF INDUSTRIAL HYGIENE AND OCCUPATIONAL MEDICINE 7, 61-67). WAYNE UNIV CONTROVERSIAL USES OF HERBICIDES (SCIENCE 166, 310). DOW OBERLIN COL THE PREPARATION OF ARYLOXYACETIC, ARYLOXYPROPIONIC AND ARYLOXYBUTYRIC ACIDS (REPORT NO. 1981). DOW WILLIAMS BM DOSSER RC HIRSCHKIND W SUMMARY OF TOXICOLOGICAL INFORMATION ON 29D AND 295T TYPE HERBICIDES AND AN EVALUATION OF THE HAZARDS TO LIVESTOCK ASSOCIATED WITH THEIR USE. ROWE VK HORMONE HERBICIDES (NC CONFERENCE ON WOODY PLANT CONTROL, RALEIGH, NC). SUMMARY OF TOXICOLOGICAL INFORMATION ON 29D AND 295T TYPE HERBICIDES AND AN EVALUATION OF THE HAZARDS TO LIVESTOCK ASSOCIATED WITH THEIR USE (DOWN TO EARTH, FORM IN 978-255). NUMBER D A T EE DOCUMENT 2051 00/00/64 AUTHOR : CLARK DE ADDRESSEE* COPYEE TYPE REPORT HUNT LM PAGES 6 TITLE PAGE 291 TOXICOLOGIC EFFECTS OF SILVEX ON YEARLING CATTLE (JAVMA 144 (7), 750-755). PALMER JS DOCUMENT 2052 07/00/68 REPORT 57 REVIEW ON THE METABOLISM OF PHENOXY COMPOUNDS IN PLANTS AND ANIMALS. AUTHOR* DON LENG ML ADDRESSEE* COPYEE < DOCUMENT 2053 05/00/69 REPORT AUTHOR: AG RESEARCH SERVICE, USD PALMER JS ADDRESSEE COPYEE: 27 THE TOXICITY OF SOME ORGANIC HERBICIDES TO CATTLE, SHEEP, AND CHICKENS. PRODUCTION RESEARCH REPORT NO. 106 (USDA). RADELEFF RD DOCUMENT 2054 12/07/53 AUTHOR: DOW ADDRESSEE: COPYEE: DOW COLLIER BL FAYERWEATHER BL MULLISON WR REPORT WATSON AJ ALQUIST FN COULTER LL GIBSON JW NATION HA 18 THE RESPONSE OF COTTON TO ALPHA(245-TRICHL0R0PHEN0XY) PROPIONIC ACID AND SEVERAL OTHER GROWTH REGULATORS (SH-348). BOUNDY RH DAVIDSON JH KAGY JF RAYNOR RN BRITTON EC DUTTON WC KELLY JA SOUTHWICK L DOCUMENT 2055 00/00/65 AUTHOR: MARTIN RP ADDRESSEE: COPYEE REPORT OK ST UNIV 3 EFFECTS OF THE HERBICIDE 245T ON BREEDING BIRD POPULATIONS (PROC. OKLA. ACAD. SCI., 235-237). DOCUMENT 2056 00/00/69 REPORT 26 TOXICITY AND HAZARDS TO MAN, DOMESTIC ANIMALS, AND WILDLIFE FOR SOME COMMONLY USED AUXIN HERBICIDES (RESIDUE REVIEWS 26, 37-62). AUTHOR: MONKS WOOD EXPERIMENTAL MONKS WOOD EXPERIMENTAL NATURE CONSERVANCY WAY JM ADDRESSEE COPYEE DOCUMENT 2057 03/26/69 AUTHOR: CLARK DE ADDRESSEE COPYEE REPORT USDA 3 DETERMINATION OF 245T ACID AND ITS PROPYLENE GLYCOL BUTYL ETHER ESTERS IN ANIMAL TISSUE, BLOOD, AND URINE (JOUR AG FD CHEM 17(6) 1168-1170, 691100). NUMBER DATE DOCUMENT 2058 00/00/68 AUTHOR BATES RR HOGAN MD ADDRESSEE COPYEEs DOCUMENT 2059 09/14/51 AUTHOR: ADAMS EH ADDRESSEE: COPYEE: DOH BRITTON JH HEATH SB RECHTIN HJ DOCUMENT 2060 06/19/62 AUTHOR: CALANDRA JC ADDRESSEE DOW COPYEE DOCUMENT 2061 12/18/58 AUTHOR: DOW ADDRESSEE COPYEE: DOCUMENT 2062 10/30/63 AUTHOR: DOW ADDRESSEE COPYEE: DOCUMENT 2063 10/26/61 AUTHOR: OLSON KJ ADDRESSEE BARRONS KC ELSHERE D HART A LUCE EN SHRADER SA COPYEE 0 4L to 00 <1 TYPE PAGES REPORT 14 COURTNEY DK MITCHELL I TEST 5 DOW BERHENKE LF DAVIDSON JH HIRSCHKIND W SOUTHWICK L REPORT 67 INDUSTRIAL BIOTEST CHART REPORT LOCKWOOD DT 7 CHART REPORT 25 DISTRB 18 REPORT OYEN F BOUNDY RH FALKENSTEIN W JONES GD LYNN GE TISDALE WL TITLE TERATOGENIC EVALUATION OF 2A5T. FALK HL GAYLOR DH NATL CANCER INST NIEHS PAGE 292 RESULTS OF TOXICOLOGICAL TESTS ON ALPHA-295-TRICHL0R0PHEN0XYPR0PI0NIC ACID. ROWE VK BRANCH CB DUTTON WC KELLY JA SUNDERLAND WW BRITTON EC HAMMER CH NELSON WL RESULTS OF 90 DAY DIETARY FEEDING OF THE PROPYLENE GLYCOL ISOBUTYL ETHER ESTER OF SILVEX (DOWCO 171) TO RATS. LABS KAY JH RESULTS OF 90 DAY DIETARY FEEDING STUDIES OF DOWANOL 97B ESTER OF SILVEX (KURON) TO RATS (K 9151-1KCRI 125185). MCCOLLISTER DD RESULTS OF 89 DAY DIETARY FEEDING STUDIES KUROSAL SL IN BEAGLE HOUNDS. RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON POLYPROPYLENE GLYCOL ISOBUTYL ETHER MIX ESTERS OF SILVEX (K NO. 4A181-1). COLBY RW GAY HH KAGY JF MCINTYRE HH WHITE LC DOW GREENE LM KILIAN DJ PERKINS RP WRIGHT N NUMBER DOCUMENT 2064 AUTHOR: ADDRESSEE* COPYEE* DATE 10/26/54 DOCUMENT 2065 AUTHOR* ADDRESSEE* COPYEE* 01/06/54 DOCUMENT 2066 AUTHOR* ADDRESSEE* COPYEE* 01/06/54 DOCUMENT 2067 AUTHOR* ADDRESSEE* COPYEE* 12/30/53 DOCUMENT 2068 AUTHOR* DOM ADDRESSEE* COPYEE* 01/06/54 DOCUMENT 2069 03/19/59 AUTHOR* KLAUDER JV ADDRESSEE* DOM COPYEE* DOCUMENT 2070 AUTHOR* ADDRESSEE* COPYEE* 00/00/61 DOCUMENT 2071 02/27/69 AUTHOR* ADDRESSEE* COPYEE* i. go r o oo 00 DOM DOM BIDLACK HD HANSEN RG I FHD I PDL I VKS MUSSELL DR SHAVER RJ TYPE CHART REPORT PAGES 14 CHART 9 CHART 3 CHART 3 CHART MOLF MA LETTER ROME VK MEMO 6 6 1 REPORT KENAGA EE ABLARD KD BYRD BC I AJB I JFK I RDM LENG ML RIDNER JM SHELDON HW 2 TITLE PAGE 293 ACUTE AND SEMI-CHRONIC TOXICITY OF SILVEX TO LABORATORY RATS. M-213 (SKIN IRRITATION). M-213. M-213 (ACUTE ORAL TOXICITY). M-213 (ACUTE ORAL TOXICITY). RESULTS OF REPEATED INSULT METHOD OF PATCH TEST WITH KURON CTTL. RESPONSE OF HUMANS TO KURON AND OTHER FORMULATIONS OF SILVEX. THE TOXICITY OF 24D 2A5T SILVEX MCPA DALAPON ERBON TCA PICLORAM DNBP AND THEIR DERIVATIVES AND FORMULATIONS TO FISH AND OTHER AQUATIC ORGANISMS (GH-P-581). MCCOLLISTER DD ALEXANDER H DAVIDSON JH I AWS I JHG I RVJ LYNN GE RITTY PM SOUTHWICK L BARRONS KC DUDDLES G I ERL I MAW I TAH MCCOY WJ SHANNON E SURGEON DK NUMBER DATE TEAL J DOCUMENT 2072 00/00/69 AUTHOR! ADDRESSEE COPYEE: BATES RR FISHBEIN L KLEIN M PETERS J DOCUMENT 2073 10/21/68 AUTHOR: DOM ADDRESSEE COPYEE: DOM HEALY MJ I DDD I GDJ I MRB KENAGA EE RAYNOR RN DOCUMENT 2074 AUTHOR: ADDRESSEE COPYEE 11/27/69 DOCUMENT 2075 01/07/59 AUTHOR DECKER E ADDRESSEE COPYEE DOCUMENT 2076 00/00/59 AUTHOR CAIN SA ADDRESSEE COPYEE DOCUMENT 2077 09/17/53 AUTHOR: ADDRESSEE: COPYEE w\ ^ oo CO DOM DOM DUTTON WC NUTTING HS TYPE PAGES MATSON AJ REPORT 14 BIONETICS GART JJ MITCHELL I PETRUCELLI L REPORT 59 LENG ML BARRONS KC I AJB I DMO I GNS IREN LANING ER SOUTHMICK L NEHS REPORT MESTMORELAND REPORT LEONARD JH REPORT NORTON TR BOUNDY RH FAYERWEATHER TITLE MILLIAMS CS MILLIAMS RT PAGE 294 BIOSSAY OF PESTICIDES AND INDUSTRIAL CHEMICALS FOR TUMORIGENICITY IN MICE A PRELIMINARY NOTE (JOUR NATL CANCER INST 42, 1101-1114). BIONET1CS RESEARCH LABOR FALK HL HART ER INNES JRM NATL CANCER INST PALLOTTA AJ ULLAND BM VALERIO MG REVIEM ON THE METABOLISM OF PHENOXY COMPOUNDS IH PLANTS AND ANIMALS (GH-P 551). MCCOLLISTER DD DAVIDSON JH I CEC I EHB I JHG JENSEN DJ LYNN GE MATSON AJ GETZENDANER ME I CMH I FHD I RJS JOHNSON JE MOSS RD MILLIAMS CS PINAL PEOPLE PLAN SUIT OVER HERBICIDES (TUCSON DAILY CITIZEN, 2) THE USE OF HERBICIDES IN NATURE SANCTUARY MANAGEMENT (PROCEEDINGS OF THE THIRTEENTH ANNUAL MEETING OF THE NE HEED CONTROL CONFERENCE 590107, 590108 AND 590109). THE ROLE OF HERBICIDES IN WILDLIFE MANAGEMENT (HERBICIDES IN VEGETATION MGNT 1422-1426). MI DEPT OF CONSERVATION UNIV OF MI HERBICIDAL ACTIVITY RESULTING FROM VOLATILITIES OF SEVERAL CHLOROPHENOXY ACID ESTERS (REPORT NO. 196). TOORNMAN BV BRITTON BC KAGY JF DAVIDSON JH KELLY JA NUMBER DATE DOCUMENT 2078 08/02/51 AUTHOR: ADDRESSEE: COPYEE: DON DON BRITTON JN FAYERNEATHER SOUTHHICK L BF DOCUMENT 2079 10/00/60 AUTHOR: FLETCHER NN ADDRESSEE COPYEEs DOCUMENT 2080 00/00/66 AUTHOR: ERNE K ADDRESSEE COPYEE: DOCUMENT 2081 01/05/51 AUTHOR: BARRONS KC ADDRESSEE COPYEE: DOCUMENT 2082 01/22/60 AUTHOR: DREESSEN J ADDRESSEE BUGH M COPYEEs DOCUMENT 2083 01/07/53 AUTHOR CORNELL ADDRESSEE COPYEEs DOCUMENT 2089 00/00/65 AUTHOR: HILTIBRAN RC ADDRESSEE COPYEE: ro 9 CO O' o TYPE PAGES REPORT 13 GREENHAGEN RH ALQUIST FN C O N N ER DL KAGY JF TITLE PAGE 295 AN EVALUATION OF 29D VOLATILITY AS A SOURCE OF 29D CONTAMINATION TO DESIRABLE PLANTS. MULLISON NR BRANCH CB DAVIDSON JH KELLY JA BRITTON EC DUTTON WC SMITH H REPORT 23 THE EFFECT OF HERBICIDES ON SOIL MICROORGANISMS (HERBICIDES 8 THE SOIL 601000). NEST OF SCOTLAND AG COL REPORT 17 DISTRIBUTION AND ELIMINATION OF CHLORINATED PHENOXYACETIC ACIDS IN ANIMALS (ACTA VET SCAND 7, 290-250). NATL VETERINARY INST SNE REPORT 11 COULTER LL COMPARATIVE HERBICIDAL EFFECTIVENESS OF CERTAIN ALKYL AND GLYCOL ESTERS OF 29D AND 295T (NORTHEASTERN NEED CONTROL CONFERENCE, NEN YORK, 510103 TO 510105). DON MULLISON HR LETTER 9 NATL AG CHEM ASSN IN ST HIGHHAY DEPT NACA'S NEGATIVE RESPONSE TO MAYO CLINIC DOCTORS STATEMENT RE ALLEGED EFFECTS OF 29D ON HUMANS CTTL. REPORT FERTIG SN 9 HERBICIDAL POISONING OF LIVESTOCK (PROCEEDINGS OF THE SEVENTH ANNUAL MEETING SUPPLEMENT OF THE NORTHEASTERN NEED CONTROL CONFERENCE 530107, 530108, 530109). REPORT 3 EFFECTS OF SOME HERBICIDES ON FERTILIZED FISH EGGS AND FRY (TRANSACTIONS OF THE AMERICAN FISHERIES SOCIETY 96(9), 919-916). IL NATURAL HISTORY SURVE NUMBER DOCUMENT 2085 AUTHOR: DOW ADDRESSEE: COPYEE: DATE 00/00/56 DOCUMENT 2086 01/29/52 AUTHOR: DUPONT ADDRESSEE: COPYEE* DOCUMENT 2087 AUTHOR: DUPONT ADDRESSEE: COPYEE 10/00/51 DOCUMENT 2088 AUTHOR: DUPONT ADDRESSEE COPYEE: 02/00/50 DOCUMENT 2089 05/00/53 AUTHOR: FERTIO SN ADDRESSEE COPYEE: DOCUMENT 2090 09/00/67 AUTHOR: ERICKSON LC ADDRESSEE: COPYEE DOCUMENT 2091 06/29/66 AUTHOR: BJORKLUND NE ADDRESSEE: COPYEE: DOCUMENT 2092 00/00/53 AUTHOR DRILL VA ADDRESSEE: COPYEE: -c O Ou C O 09 TYPE PAGES REPORT WARDEN RL 5 ABSTRACT 2 PRESENT GRASSELLI CHEM ABSTRACT 1 GRASSELLI CHEM ABSTRACT FARWELL ED 1 REPORT 7 NY ST COL OF AG REPORT HIGGINS RE 9 REPORT ERNE K 19 REPORT HIRATZKA T 7 TITLE TOXICITY OF 24D TO BEES PAGE 296 SUMMARIES OF PRESENTATIONS (FOURTH IL CUSTOM SPRAY OPERATIONS TRAINING SCHOOL, 520124 TO 520125, URBANA IL). STAHLER LM (ASSOC FOOD & DRUG OFFICE OF U.S. 15, 122-133). LEHMAN AJ MI QUARTERLY BULLETIN 32, 378-385. GRASSELLI CHEM GRIGSBY BH HERBICIDAL POISONING OF LIVESTOCK (REA BULLETIN 169-7). HERBICIDES (HOW POISONOUS ARE THEY) (CURRENT INFORMATION SERIES). ID AG EXTENSION SERVICE SEELY Cl TOXICOLOGICAL STUDIES OF PHENOXYACETIC HERBICIDES IN ANIMALS (ACTA VET. SCAND. 7, 364-390). NATL VETERINARY INSTITUT ROYAL VET COL SWEDEN TOXICITY OF 24D AND 245T. A REPORT ON THEIR ACUTE AND CHRONIC TOXICITY IN DOGS (INDUSTRIAL HYGIENE AND OCCUPATIONAL MEDICINE, 61-67) . WAYNE UNIV COL OF MEDICI NUMBER DOCUMENT 2093 AUTHOR: DON ADDRESSEE: COPYEE DATE 05/29/58 TYPE PAGES PRESENT HYMAS TA 8 DOCUMENT 2099 09/29/69 AUTHOR: ADDRESSEE COPYEE: BATES RR GART JJ MITCHELL I PETRUCELLI L REPORT 19 BIONETICS HART ER NATL CANCER INST ULLAND BM DOCUMENT 2095 AUTHOR: ADDRESSEE COPYEE: 00/00/57 CHART DOCUMENT 2096 09/01/68 REPORT AUTHOR: FED WATER POLLUTION CONT ADDRESSEE COPYEE: DOCUMENT 2097 01/25/60 AUTHOR: ADDRESSEE: COPYEE* DOW DOW ELSHERE D HART A KILIAN DJ PERKINS RP REPORT WOLF MA BARRONS KC GAY HH HYMAS TA LUCE EN STENGER VA DOCUMENT 2098 AUTHOR: DOW ADDRESSEE COPYEE DOW 08/30/50 REPORT DRILL VA BRITTON JW 2 DOCUMENT 2099 08/23/50 AUTHOR: ADDRESSEE: COPYEE: r-\ DOW DOW DUTTON WC LYNN GE to REPORT 9 ROWE VK ALLEN WW HIRSCHFIELD SUNDERLAND WW TITLE PAGE TOXICITY OF HERBICIDES TO DOMESTIC ANIMALS (ACD FILE HG-51). 297 BIOASSAY OF PESTICIDES AND INDUSTRIAL CHEMICALS FOR TUMORIGENICITY IN MICE. A PRELIMINARY NOTE. FALK HL FISHBEIN L INNES JRM KLEIN M PALLOTTA AJ PETERS J VALERIO MG RELATIVE TOXICITY OF SOME HERBICIDES TO RATS. MATER QUALITY CRITERIA!REPORT OF THE NATL TECH ADVISORY COMM TO THE SECRETARY OF THE INTERIOR). RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON ESTERON 295 OS CM-1257). (BC T2.30-167-DC12 2182). BOUNDY RH GREENE LM JONES GD LYNN GE TISDALE ML COLBY RM HAMMER OH KAGY JF MCINTYRE HH MRIGHT N INTERIM REPORT ON THE ACUTE AND SUBACUTE ORAL TOXICITY OF 295T ACID FOR DOGS (BC T23.19-23-9K12 5105). ROME VK MAYNE UNIV RESULTS OF TOXICOLOGICAL TESTS ON 295T (12 5109)(BC T23.19-23-2 8 3). BRITTON JM IRISH DD DOSSER RC KAGY JF NUMBER JOCUMENT 2100 AUTHOR DOW ADDRESSEE ;OPYEE AJW GEL JKL LAD OHH RWC DATE 04/06/62 TYPE PAGES REPORT 19 LANING ER AWS HJ JLS LEW RGH TRN DOCUMENT 2101 \UTHOR \DDRESSEE :o p y e e 00/00/67 NEWS 1 DOCUMENT 2102 00/00/66 AUTHOR: CHEM ABSTRACTS RYAN RW ADRESSEE :o p y e e ABSTRACT 1 INST WASSER BODEN DOCUMENT 2103 00/00/65 AUTHOR CHEM ABSTRACTS ADDRESSEE COPYEE ABSTRACT KAYSER H 1 DOCUMENT 2104 00/00/62 ABSTRACT 1 AUTHOR ANDERSON A KIVIMAE A ADDRESSEE COPYEE CHEM ABSTRACTS WADNE C DOCUMENT 2105 00/00/63 ABSTRACT AUTHOR CHEM ABSTRACTS COLLIER C LA WILD LIFE & FISHERIES ADDRESSEE COPYEE 1 -C . co O "A CD CO TITLE PAGE 298 WOODY PLANT CONTROL WITH THREE CHLOROPICOLINIC ACIDS (CRI 148317) CGS-503). EHB FHN JAK JEJ JWV KCB LJL LTW RHB RPP WR VIETNAM DEFOLIATION GETS RIGHT OF WAY CHEMICALS. TOXICITY OF HERBICIDES TO AQUATIC LIFE. ANIMALS USED AS FISH FOOD (GAS-WASSERFACH 107(10), 256-260)CCHEM ABSTRACTS). LUFTHY KAYSER H LUEDEMANN D TOXICITY OF HERBICIDES TO AQUATIC LIFE. TOXICITY TO FISH (GAS-WASSERFACH 106(8), 220-223MCHEM ABSTRACTS 62, 13778). LUEDEMANN D RYAN RW THE TOXICITY OF SOME HERBICIDES TO CHICKS (KGL LANTBRUKSHOGSKOL OCH ST LANTBRUKSFORSOK, ST HUSDJURSFORSOK SARTRYCK OCH FORHANDSMEDD 155, 1 8 H C H E M ABSTRATS 59, 5547-5548, 630000). DAHL S INST TECHNOL STOCKHOLM VARIATIONS IN TOXICITY TO BLUEGILL SUNFISH OF PHENOXY HERBICIDES (WEEDS 11(1), 50-53)(CHEM ABSTRACTS 58, 10553). DAVIS JT HUGHES JS NUMBER OCUMENT 2106 DATE 00/00/61 UTHOR* CHEM ABSTRACTS DDRESSEE > OPYEE * OCUMENT 2107 00/00/61 UTHOR* BAKER BR SKINNER MA DDRESSEE* OPYEE* OCUMENT 2108 00/00/61 UTHOR* CHEM ABSTRACTS OH DEPT OF AGR DDRESSEE* OPYEE* lOCUMENT 2109 00/00/60 UTHOR* BODENSTEIN G MULLERBASTGEN G ADRESSEE* OPYEE* lOCUMENT 2110 00/00/54 \UTHOR * CHEM ABSTRACTS SEIDEN R ADDRESSEE* :o p y e e * )OCUMENT 2111 00/00/53 AUTHOR* CAMPBELL CL WAYNE UNIV IDDRESSEE* :o p y e e * -*.0 V*J O to CO TYPE ABSTRACT PAGES DYBING 0 TITLE PAGE 299 TOXICITY OF INSECTICIDES USED FOR PARASITE CONTROL IN PLANT PROTECTION (FINSK VETERINARSTIDSKR 67(1), 7-8, 13-18, 21-26XCHEM ABSTRACTS 58, 3813). LAAKSO TM NORGES VETERINAERHOGSKUL ABSTRACT 1 POTENTIAL ANTICANCER AGENTS. NONCLASSICAL ANTIMETABOLITES. SOME FACTORS IN THE DESIGN OF EXOALKYLATING ENZYME INHIBITORS PARTICULARLY OF LACTIC DEHYDROGENASE (JOUR MED PHARM CHEM 11, 633-657, 600000)(CHEM ABSTRACTS 55, 12662). CHEM ABSTRACTS LEE MW MARTINEZ AP STANFORD RESARCH INST CA TEERI AE TONG E ABSTRACT 2 GOLDSTEIN HE OBSERVATIONS ON CATTLE SHEEP AND SMINE EXPOSED TO 24D 245T AND DALAPON HERBICIDES (PROC SOUTHERN WEED CONF, 13TH, 600000, 5-ll)(CHEM ABSTRACTS 55, 8740-8741). JACOBSON M LONG JF ABSTRACT 1 CHEM ABSTRACTS TOXICITY OF PRESENT DAY PESTICIDES FOR FISH. THE TOXICITY OF SOME HERBICIDES TO FISH (PLANZENKRANKH PHLANZENSCHUTZ 67, 150-153)(CHEM ABSTRACT 54, 25535). FIRMA CH BOEHRINGER SOHN GREEN EL ABSTRACT DOW 1 SUMMARY OF TOXICOLOGICAL INFORMATION ON 24D AND 245T TYPE HERBICIDES AND AN EVALUATION OF THE HAZARDS TO LIVESTOCK ASSOCIATED WITH THEIR USE (AM JOUR VET RES 15, 622-629KCHEM ABSTRACTS 49, 1974). HYMAS TA ROWE VK ABSTRACT 1 CHEM ABSTRACTS TOXICITY OF 24D AND 245T. A REPORT ON THEIR ACUTE AND CHRONIC TOXICITY IN DOGS (ARCH IND HYG OCCUPATIONAL MED 7, 61-67)(CHEM ABSTRACTS 47, 12618). DRILL VA HIRATZKA T NUMBER DOCUMENT 2112 DATE 00/00/52 AUTHOR CHEM ABSTRACTS ADDRESSEE* COPYEE* TYPE ABSTRACT FDA PAGES 3 TITLE PAGE 300 CHEMICALS IN FOODS. A REPORT TO THE ASSOCIATION OF FOOD AND DRUG OFFICIALS ON CURRENT DEVELOPMENTS (ASSOC FOOD 8 DRUG OFFICIALS U.S. QUART BULL 15, 82-89, 510000HCHEM ABSTRACTS 46, 2701-2704). LEHMAN AJ SUMERFORD WT DOCUMENT 2113 02/00/68 AUTHOR* SCHULTZ KH ADDRESSEE* COPYEE0* DOCUMENT 2114 00/00/57 AUTHOR* COLOMB L ADDRESSEE* COPYEE* REPORT 13 CLINICAL PICTURE AND ETIOLOGY OF CHLORANCE ARBEITSMEDIZIN-SOZIALMEDIZIN-ARBEITSHYGIENE 3(2), 25-29). UNIV DERMATOLOGY CLINIC NEWS 9 REMARKS ON HALOGEN ACNE (LE JOUR DE MEDECINE DE LYON 38, 899-903). REPORT DUGOIS P DOCUMENT 2115 08/00/68 REPORT 74 AUTHOR* BIONETICS HART RE NIEHS FALK H ADDRESSEE* COPYEE* INNES JRM PALLOTTA AJ EVALUATION OF CARCINOGENIC, TERATOGENIC, AND MUTAGENIC ACTIVITIES OF SELECTED PESTICIDES AND INDUSTRIAL CHEMICALS VOLUME 1 CARCINOGENIC STUDY. KOTIN P NIEHS DOCUMENT 2116 AUTHOR* USDA ADDRESSEE* COPYEE* 05/00/65 REPORT 48 AERIAL APPLICATION OF AGRICULTURAL CHEMICALS (USDA AG HANDBOOK 287). DOCUMENT 2117 00/00/66 AUTHOR* ERNE K ADDRESSEE* COPYEE* REPORT 9 STUDIES ON THE ANIMAL METABOLISM OF PHENOXYACETIC HERBICIDES (ACTA VET. SCAND. 7, 264-271). NATL VETERINARY INST SHE DOCUMENT 2118 00/00/66 AUTHOR* ERNE K ADDRESSEE* COPYEE* REPORT 20 DETERMINATION OF PHENOXYACETIC HERBICIDE RESIDUES IN BIOLOGICAL MATERIALS (ACTA VET. SCAND. 7, 77-96). NATL VETERINARY INST SWE -G to CD Crt NUMBER DATE DOCUMENT 2119 00/00/66 AUTHOR * ERNE K ADDRESSEE COPYEE DOCUMENT 2120 12/01/67 AUTHOR DOCKTER KM MIDWEST RES INST ADDRESSEE DOD COPYEE DOCUMENT 2121 12/01/67 AUTHOR ADDRESSEE COPYEE DAY BE JENKINS JH UC RIVERSIDE DOD DOCUMENT 2122 12/01/67 AUTHOR ADDRESSEE COPYEE DAY BE GOODSON LH MCFARLANE JO UNIV OF GA DOD DOCUMENT 2123 12/01/67 AUTHOR: DAY BE GOODSON LH MCFARLANE JO UNIV OF GA ADDRESSEE DOD COPYEE TYPE PAGES REPORT 39 NATL VETERINARY INST ABSTRACT 2 GADBERRY HM CHART 3 REPORT GERRISH OB MCFARLANE JO UNIV OF GA REPORT 37 DOCKTER KM HENDERSON NC MIDWEST RES INST UNIV OF MO REPORT 6 DOCKTER KM HENDERSON NC MIDWEST RES INST UNIV OF MO I ro C> <T> TITLE PAGE 301 STUDIES ON THE ANALYTICAL CHEMISTRY AND TOXICOLOGY OF PHENOXY HERBICIDES. SHE ASSESSMENT OF ECOLOGICAL EFFECTS OF EXTENSIVE OR REPEATED USE OF HERBICIDES (DOCUMENT CONTROL DATA, RSD). GOODSON LH HOUSE HB SOIL ORGANISMS WHICH DECOMPOSE HERBICIDES (TABLE A-6) (ASSESSMENT OF ECOLOGICAL EFFECTS OF EXTENSIVE OR REPEATED USE OF HERBICIDES, FINAL REPORT). HENDERSON NC MIDWEST RES INST UNIV OF MO HOUSE HB RINGLE DA ECOLOGICAL CONSEQUENCES OF HERBICIDE USE (ASSESSMENT OF ECOLOGICAL EFFECTS OF EXTENSIVE OR REPEATED USE OF HERBICIDES, FINAL REPORT). GADBERRY HM GERRISH OB HOUSE HB JENKINS JH RINGLE DA UC RIVERSIDE SOME FACTORS DETERMINING THE FATE OF HERBICIDES, TEMPERATURE (ASSESSMENT OF ECOLOGICAL EFFECTS OF EXTENSIVE OR REPEATED USE OF HERBICIDES, FINAL REPORT). GADBERRY HM GERRISH OB HOUSE HB JENKINS JH RINGLE DA UC RIVERSIDE NUMBER DOCUMENT 2124 DATE 12/01/67 AUTHOR ADDRESSEE COPYEE DAY BE GOODSON LH MCFARLANE JO UNIV OF GA DOD DOCUMENT 2125 12/01/67 TYPE REPORT PAGES 3 DOCKTER KW HENDERSON NC MIDWEST RES INST UNIV OF MO REPORT 7 AUTHOR ADDRESSEE COPYEE DAY BE GOODSON LH MCFARLANE JO UNIV OF GA DOD DOCUMENT 2126 12/01/67 AUTHOR ADDRESSEE COPYEE DAY BE GOODSON LH MCFARLANE JO UNIV OF GA DOD DOCUMENT 2127 12/01/67 AUTHOR ADDRESSEE COPYEE DAY BE GOODSON LH MCFARLANE JO UNIV OF GA DOD DOCUMENT 2128 12/01/67 AUTHOR ADDRESSEE COPYEE . DAY BE GOODSON LH MCFARLANE JO UNIV OF GA DOD Vii t o -o CO <dv) -si DOCKTER KW HENDERSON NC MIDWEST RES INST UNIV OF MO REPORT 3 DOCKTER KW HENDERSON NC MIDWEST RES INST UNIV OF MO REPORT 3 DOCKTER KW HENDERSON NC MIDWEST RES INST UNIV OF MO CHART 1 DOCKTER KW HENDERSON NC MIDWEST RES INST UNIV OF MO TITLE PAGc 302 HERBICIDE RESIDUES AND THEIR PERSISTENCE IN VEGETATION, CHLOROPHENOXY ACIDS (ASSESSMENT OF ECOLOGICAL EFFECTS OF EXTENSIVE OR REPEATED USE OF HERBICIDES, FINAL REPORT). GADBEKRY HM GERRISH OB HOUSE HB JENKINS JH RINGLE DA UC RIVERSIDE TOXIC EFFECTS OF HERBICIDES (MUTAGENIC EFFECTS ON PLANTS, INSECT DEVELOPMENT, CONCENTRATION IN FOOD CHAINS, HERBICIDE SPRAYING EFFECTS ON MAN) (ASSESSMENT OF ECOLOGICAL EFFECTS OF EXTENSIVE OR REPEATED USE OF HERBICIDES, FINAL REPORT) CTTL. GADBERRY HM GERRISH OB HOUSE HB JENKINS JH RINGLE DA UC RIVERSIDE EFFECTS OF HERBICIDES ON MICROORGANISMS (ASSESSMENT OF ECOLOGICAL EFFECTS OF EXTENSIVE OR REPEATED USE OF HERBICIDES, FINAL REPORT). GADBERRY HM GERRISH OB HOUSE HB JENKINS JH RINGLE DA UC RIVERSIDE TOXICOLOGICAL EFFECTS OF HERBICIDES, SILVEX (ASSESSMENT OF ECOLOGICAL EFFECTS OF EXTENSIVE OR REPEATED USE OF HERBICIDES, FINAL REPORT). GADBERRY HM GERRISH OB HOUSE HB JENKINS JH RINGLE DA UC RIVERSIDE TOXICITY OF HERBICIDES TO ESTUARINE ORGANISMS (ASSESSMENT OF ECOLOGICAL EFFECTS OF EXTENSIVE OR REPEATED USE OF HERBICIDES FINAL REPORT). GADBERRY HM GERRISH OB HOUSE HB JENKINS JH RINGLE DA UC RIVERSIDE NUMBER DOCUMENT 2129 DATE 1 2 /0 1 /6 7 AUTHOR DAY BE GOODSON LH MACFARLANE JO UNIV OF GA ADDRESSEE DOD COPYEE DOCUMENT 2130 12/01/67 AUTHOR DAY BE GOODSON LH MACFARLANE JO UNIV OF GA ADDRESSEE DOD COPYEE DOCUMENT 2131 AUTHOR DON ADDRESSEE COPYEE 08/00/50 DOCUMENT 2132 AUTHOR DOM ADDRESSEE COPYEE' 00/00/50 DOCUMENT 2133 '12/08/67 TYPE REPORT PAGES 22 DOCKTER KM HENDERSON NC MIDMEST RES INST UNIV OF MO REPORT 70 DOCKTER KM HENDERSON NC MIDMEST RES INST UNIV OF MO REPORT 9 REPORT 5 MCCOLLISTER DD REPORT 15 AUTHOR ADDRESSEE COPYEE DOCUMENT 2139 00/00/57 REPORT AUTHOR INTL INFORMATION CLEARIN KIMMIG J ADDRESSEE DOM SAUERS R COPYEE 5 ro CO GO TITLE PAGE 303 HERBICIDE APPLICATION ON WATERWAYS, PONDS, LAKES AND RESERVOIRS (ASSESSMENT OF ECOLOGICAL EFFECTS OF EXTENSIVE OR REPEATED USE OF HERBICIDES, FINAL REPORT). GADBERRY HM GERRISH OB HOUSE WB JENKINS JH RINGLE DA UC RIVERSIDE HERBICIDE APPLICATION ON VARIOUS LAND AREAS (ASSESSMENT OF ECOLOGICAL EFFECTS OF EXTENSIVE OR REPEATED USE OF HERBICIDES, FINAL REPORT). GADBERRY HM GERRISH OB HOUSE WB JENKINS JH RINGLE DA UC RIVERSIDE RESULTS OF TOXICOLOGICAL TESTS ON 2A5T. THE ACUTE ORAL TOXICITY OF 2A5T TO RATS, MICE, GUINEA PIGS AND CHICKS. ROWE VK SPENCER HC PETITION FOR THE ESTABLISHMENT OF TOLERANCES FOR THE PESTICIDE CHEMICAL, 2A5T ON RAW AGRICULTURAL COMMODITIES. SECTION C FULL REPORTS OF INVESTIGATIONS MADE WITH RESPECT TO THE SAFETY OF THE PESTICIDE CHEMICAL, 2A5T. CHLORINATED AROMATIC CYCLIC ETHER AS CAUSE OF SO CALLED CHLORACNE (NATURWISSENSCHAFTEN AA, 337-338). SCHULZ KH UNIV SKIN CLINIC WGERM HUMBER DATE TYPE PAGES DOCUMENT 2135 00/00/69 REPORT A AUTHOR* DARTMOUTH MEDICAL SCHOOL GOSSELIN RE ADDRESSEE* COPYEE DOCUMENT 2136 05/20/61 REPORT 9 AUTHOR BAUER H ADDRESSEE COPYEE SCHULZ KH DOCUMENT 2137 00/00/57 AUTHOR SCHULZ KH ADDRESSEE* COPYEE* REPORT WGERM 8 DOCUMENT 2138 00/00/53 REPORT 7 AUTHOR DRILL VA ADDRESSEE* COPYEE* HIRATZKA T DOCUMENT 2139 00/00/53 AUTHOR* CROKER BH ADDRESSEE* COPYEE REPORT 10 UNIV OF SHEFFIELD DOCUMENT 2140 00/00/69 AUTHOR ANH TK TRA DX ADDRESSEE COPYEE* REPORT BA HV TUNG TT 16 DOCUMENT 2141 06/18/80 REPORT 45 AUTHOR HAZARD ALERT SYSTEM CA DEPT OF HEALTH CA ADDRESSEE COPYEE* to CO CO TITLE PAGE 24D(24D)(CLINICAL TOXICOLOGY OF COMMERCIAL PRODUCTS, ACUTE POISONING SECTION 3 THERAPEUTICS INDEX, 79-81). SMITH RP 304 BERUFLICHE VERGIFTUNGEN BEI DER HERSTELLUNG VON CHLORPHENOL-VERBINDUNGENCARCHIV FR GEWERBEPATHOLOGIE UND GEWERBEHYGIENE 18, 538-555). SPIEGELBERG U UNIVERSITATS KRANKENHAUS UNTERSUCHUNGEN ZUR TIOLOGIE DER CHLORACNE(ARCHIV FR KLINISCHE UND EXPERIMENTELLE DERMATOLOGIE 206, 589-596). TOXICITY OF 24D AND 245T. A REPORT ON THEIR ACUTE AND CHRONIC TOXICITY IN DOGS (IND. HYGIENE AND OCCUPATIONAL MEDICINE 7C61), 61-67). WAYNE UNIV COL OF MEDICI EFFECTS OF 24D AND 245T ON MITOSIS IN ALLIUM CEPA (BOTANICAL GAZETTE 114, 274-283). ENG LES EFFETS CLINIQUES DE LUTILISATION MASSIVE ET CONTINUE DE DEFOLIANIS SUR LA POPULATION CIVILE (ETUDE LIMINAIRE). DELEGATION DE LA RDVN HUYEN NX TUYEN BQ 24D EVALUATION OF THE HUMAN HEALTH HAZARDS. DEPT OF IND RELATIONS CA NUMBER DATE DOCUMENT 2142 08/22/80 AUTHOR BEZUGLYI VP ADDRESSEE COPYEE DOCUMENT 2143 08/00/68 AUTHOR COURTNEY KD ADDRESSEE COPYEE DOCUMENT 2144 04/00/52 AUTHOR KNIGHT GF ADDRESSEE* COPYEE DOCUMENT 2145 00/00/65 AUTHOR* FLETCHER WW ADDRESSEE COPYEE* DOCUMENT 2146 07/20/66 AUTHOR COLLINS L SALAS F ADDRESSEE COPYEE* DOCUMENT 2147 05/20/55 AUTHOR ADDRESSEE* COPYEE* DOW DOW BARRONS KC COLBY RW KAGY JF LYNN GE WRIGHT N TYPE PAGES TITLE PAGE 305 MEMO 9 CLINIC FOR DELAYED CONSEQUENCES OF ACUTE CONTAMINATION FROM 24D. REPORT INST FOR HYGIENE 8 TOX 0 PRESENT REPORT 7 245T IN THE RAT EXCRETION PATTFRN, SERUM LEVELS, PLACENTAL TRANSPORT, AND METABOLISM (PESTICIDES SYMPOSIAUINTER AMERICA^ CONFERENCE ON TOXICOLOGY AND OCCUPATIONAL MEDICINE, UNIV OF MIAMI). REPORT 15 WHAT ARE PESTICIDES DOING TO HUMAN BEINGS? (MODERN NUTRITION MAGAZINE 1-14, 520400, 520900, AND 521200). PRICE-POTTENGER NUTRITIO REPORT SHENNAN JL THE GROWTH IN VITRO OF MICRO-ORGANISMS IN THE PRESENCE OF SUBSTITUTED PHENOXYACETIC AND PHENOXYBUTYRIC ACIDS (WEED RES 5; 266-274). UNIV OF STRATHCLYDE SCOT REPORT DOW TARKOWSKI D REPORT ON THE FORMATION OF CHLORACNE EXCITERS IN THE PRODUCTION OF 245 TRICHLOROPHENOL (CRI 183451). JOHNSON RL RAVKOVITZ H HIDIGER AH REPORT MCCOLLISTER DD ALLINSON BESHGETEER AW DAVIDSON JH KELLY JA MACCUTCHEEN WRIGHT P RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON 245T DOWANOL 97B ESTER (T25.14-106-1) (CRI 125180). WOLF MA ALQUIST FN BOUNDY RH GAY HH KILIAN DJ SUNDERLAND WW BACON KD BRITTON EC GREENE LM LUCE EN WHITE LC :.o o- o NUMBER DATE DOCUMENT 2148 08/24/50 AUTHOR: ADAMS DM ADDRESSEE: DOM DOSSER RC LYNN GE COPYEE: DOCUMENT 2149 06/19/62 AUTHOR: CALANDRA JC MCCOLLISTER DD ADDRESSEE: COPYEE: DOW COLBY RW GREENE LM KILIAN DJ NASH HA VANVALKENBURG M DOCUMENT 2150 12/16/49 AUTHOR: DOM ADDRESSEE: DOM COPYEE: DOM BOUNDY FH KELLY JA DOCUMENT 2151 07/29/54 AUTHOR: DOM ADDRESSEE-' COPYEE: DOM BESHGETOOR AM GREENE LM LYNN GE WRIGHT P DOCUMENT 2152 00/00/54 AUTHOR DOW ADDRESSEE: COPYEE: TYPE PAGES REPORT 4 DOW ALLEN MM DUTTON WC REPORT DOM 67 BARRONS KC DOSSER RC HART A LUCE EN PERKINS RP WRIGHT N REPORT DRILL VA BRITTON JW BRITTON JW DOSSER RC LYNN GE 16 REPORT 9 MCCOLLISTER DD ALLISON RL BOUNDY RH KAGY JF MACUTCHEON SM REPORT HYMAS TA 8 TITLE PAGE 306 RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON ESTERONS 245T AND 24D (BRUSH KILLER) (T25.14-86-1) (CRI 125176). ROWE VK BARRONS KC BRITTON JW IRISH DD KAGY JF RESULTS OF 90 DAY DIETARY FEEDING OF PROPYLENE GLYCOL ISOBUTYL ETHER ESTER OF SILVEX (DOWCO 171) TO RATS (CRI 125199). IND BIOTEST LAB KAY JH BOUNDY RH FALKENSTEIN WJ JONES GD LYNN GE SHRADER SA BROWN R GAY HH KAGY JF MCINTYRE HH TISDALE ML INTERIN REPORT ON THE ACUTE AND SUBACUTE ORAL TOXICITY OF 245T FOR DOGS (T23.14-23-4) (CRI 125105). ROWE VK WAYNE UNIV ALQUIST FN GAY HH MACCUTCHEN SM BARRONS KC KAGY JF SUNDERLAND WW RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON BUTYL (AND ISOBUTYL) ALPHA (245TRICHL0R0PHEN0XY) PROPIONATE (T25.14-236-1MCRI 12 5187). OYEN F ALQUIST PN BRITTON EC KELLY JA SUNDERLAND WW BACON KD GAY HH LUCE EN WRIGHT N SUMMARY OF TOXICOLOGICAL INFORMATION ON 24D AND 245T TYPE HERBICIDES AND AN EVALUATION OF THE HAZARDS TO LIVESTOCK ASSOCIATED WITH THEIR USE (AM JOUR OF VETERINARY RES 15(57), 622-629). ROWE VK NUMBER DOCUMENT 2153 DATE 00/00/65 AUTHOR: DON ADDRESSEE* COPYEE* DOCUMENT 2154 AUTHOR* DON ADDRESSEE* COPYEE* 00/00/65 DOCUMENT 2155 AUTHOR: DON ADDRESSEE* COPYEE* 10/25/65 DOCUMENT 2156 AUTHOR* DOW ADDRESSEE* COPYEE* 05/00/69 DOCUMENT 2157 07/08/57 AUTHOR* COULTER LL ADDRESSEE COPYEE: DOW BOUNDY RH HAMMER OH LANG HC DOCUMENT 2158 02/26/68 AUTHOR: BOEHRINGER W TOLKMITH H ADDRESSEE* TRAPP W COPYEE: DOCUMENT 2159 02/15/67 AUTHOR: DOW ADDRESSEE* DOW COPYEE* CORBIN WL PLETCHER DE TYPE REPORT OYEN F PAGES 20 REPORT OYEN F 15 REPORT DUNN FL 20 CHART 2 REPORT 15 DOW LYNN GE BRITTON JW JOHNSON JE MULLISON WR LETTER 2 CH BOEHRINGER SOHN LETTER ROWE VK DIXON WR GOWELL JM 2 TITLE PAGE 307 REPORT OF INDIVIDUAL MICROSCOPIC EXAMINATION OF TISSUES FROM MALE AND FEMALE RATS MAINTAINED FOR TWO YEARS ON DIETS CONTAINING KUROSAL SL. SUMMARY OF PATHOLOGY ON MALE AND FEMALE RATS FED KUROSAL SL IN THE DIET FOR 18 MONTHS. TCDBD. I JPM TINKER B COMPARISON OF ACUTE ORAL TOXICITIES OF HERBICIDE FORMULATIONS IN SMALL ANIMALS. INVERT EMULSION FORMULATIONS OF HALOPHENOXY AKLYL ACIDS AND ESTERS FOR WEED AND BRUSH CONTROL, REVIEW OF STATUS FOR ADVANCEMENT TO STAGE A (REPORT AD-20). LYNN GE ALLEN WW COLBY RW KAGY JF PRESCOTT RF BARRONS KC FAYERWEATHER BL KELLY JA ROWE VK CH BOEHRINGER SOHN PROGRESS CONCERNING CHLORACNE ACTIVE MATERIALS CTTL. DOW MERZ H TCC (ST LOUIS, MO) PHONED DOW ASKING FOR ADVICE ON PLANT SAFETY FOLLOWING A CHLORACNE OUTBREAK CTTL. HOLDER BB MCCOY WJ NUMBER DOCUMENT 2160 AUTHOR< DOW ADDRESSEE COPYEE DOCUMENT 2161 AUTHOR DOW ADDRESSEE COPYEE DOCUMENT 2162 AUTHOR DOW ADDRESSEE COPYEE DOCUMENT 2163 AUTHOR DOW ADDRESSEE COPYEE DOCUMENT 2164 AUTHOR DOW ADDRESSEE COPYEE DOCUMENT 2165 AUTHOR DOW ADDRESSEE COPYEE DOCUMENT 2166 AUTHOR DOW ADDRESSEE COPYEE DOCUMENT 2167 AUTHOR DOW ADDRESSEE COPYEE DATE 05/12X65 TYPE PAGES REPORT 1 OHARE CP 04/01/65 REPORT OHARE CP 1 05/12/65 REPORT OHARE CP 1 04/01/65 REPORT OHARE CP 1 04/15/65 REPORT OHARE CP 1 03/26/65 REPORT OHARE CP 1 06/01/65 REPORT OHARA CP 1 05/12/65 REPORT OHARE CP 1 TITLE 245 CL3PHEN0L (CHCL3 EXTRACT) 3-2-'65 O.OI PPM SYM. DIOXIN CONC). PAGE 308 DIOXIN (1*1 245 CL3PHEN0L (CHCL3) EXTRACT 3-2-65 0.01 PPM. SYM. DIOXIN 1*1 DIOXIN CONC. 245 CL3PHEN0L (DISTILLED) 3-2-*65 0.01 PPM SYM. DIOXIN. 245 CL3PHEN0L (DISTILLED) 3/2/65 0.01 PPM SYM DIOXIN (ENTRIE SAMPLE). 245T ACID (10AW13) SOLID 1.0 PPM SYM. DIOXIN (ENTIRE SAMPLE). 245T ACID CHCL3 EXTRACT (10AW13) 0.20 PPM SYM. DIOXIN 1*1 DIOXIN CONC. 245T ACID (10AW13) SOLID 0.04 PPM SYMMETRICAL DIOXIN (ENTIRE SAMPLE). 245T ACID (10AW13) SOLID 0.01 PPM SYM. DIOXIN (ENTIRE SAMPLE). NUMBER DOCUMENT Z168 AUTHORi DON ADDRESSEE* COPYEEs DATE 04/01/65 DOCUMENT 2169 AUTHORS DON ADDRESSEES COPYEEs 03/30/65 DOCUMENT 2170 AUTHOR! DON ADDRESSEE DOM COPYEEs 07/01/65 DOCUMENT 2171 AUTHORS DOM ADDRESSEE DOM COPYEEs 06/17/65 DOCUMENT 2172 AUTHOR: ADDRESSEE DOM COPYEEs 06/24/65 DOCUMENT 2173 05/04/65 AUTHOR DOM ADDRESSEE* COPYEEs DOSSER RC DOCUMENT 2174 02/16/65 AUTHOR* DOEDENS JD ADDRESSEE* DOM HUTCHENREUTHER C SMILEY RN COPYEEs DOCUMENT 2175 AUTHOR: DOM ADDRESSEE* COPYEEs 00/00/69 TYPE PAGES REPORT 1 OHARE CP REPORT OHARE CP 1 REPORT 1 MUTCHLER JE SILVERSTEIN LG REPORT 1 MUTCHLER JE SILVERSTEIN LG LETTER 1 MULHOLLAND R MINUTES MHITE LC SMITH HA 2 LETTER DOM FEINAUER HM OTIS CE STAEHLING EC 2 REPORT 3 ^ oCO TITLE 2A5T ACID (10AN13) SOLID. SAMPLE). PAGE 309 0.01 PPM SYMMETRICAL DIOXIN (ENTIRE 2A5T ACID CHCL3 EXTRACT (10AW13) STARTING MATERIAL (1*1 DIOXIN CONC.). 2A5T FROM 267 BLDG (REQUEST FOR SCREENING OR APPLICATION TESTING). 2A5T FROM 267 BLDG (REQUEST FOR SCREENING OR APPLICATION TESTING). 245-TRICHL0R0PHEN0L, THE "T" ACIDS AND ASSOCIATED ACNEGENS. 245T PRODUCT SPECIFICATION. 2A5-TRICHL0R0PHEN0L. GRANT LB RILEY FH TUCKER JC HARRIS JW SILVERSTEIN L CHRONOLOGY OF CHLORACNE TESTING IN BRL NUMBER DATE DOCUMENT 2176 03/10/65 AUTHOR: DOW ADDRESSEE* DOW DEODENS JD HANSEN KY HUTCHENREUTHER CO PALSEY WB SMILEY RN COPYEE TYPE PAGES LETTER 2 SILVERSTEIN LG AMSTUTZ FC FEINAUER HW HARRIS JW LYNN GE PLETCHER DE STAEHLING EC DOCUMENT 2177 03/16/49 AUTHOR: DOW ADDRESSEE AM MUTUAL LIABI COPYEE: ALLEN WW LETTER ROWE VK THOMPSON EW 1 DOCUMENT 2178 AUTHOR: DOW ADDRESSEE DOW COPYEE: 05/11/50 LETTER 1 ROWE VK BROADBENT RW DOCUMENT 2179 . 09/13/56 AUTHOR: DOW ADDRESSEE CHEMI TROL CHEM COPYEE: CONNER DL LETTER ROWE VK KARLOVETZ F MCCOY KW 2 DOCUMENT 2180 09/30/55 AUTHOR: DOW ADDRESSEE: CHEMI TROL CO COPYEE BRYANT CA DOCUMENT 2181 03/25/54 AUTHOR BECKWITH C ADDRESSEE DOW COPYEE: KARLOVETZ F YEST FH LETTER ROWE VK KARLOVETZ F CONNER D 5 LETTER DOW SMITH H ROWE VK 2 DOCUMENT 2182 01/19/62 AUTHOR DOW ADDRESSEE DENTE J COPYEE: MCCOY WJ LETTER 1 REED DL SORDONI CONSTRU RITTY PM CO Oo cn TITLE HAZARD OF MONSANTO T ACID BARRONS KC GILL WH HOFF RC MCCOY WJ RILEY FH TUCKER JC CORBIN ML GRANT LB HOYLE HR OTIS CE ROWE VK HILTSE MG EXPERIMENTAL STUDIES ON LABORATORY ANIMALS CTTL. PAGE 310 REQUEST FOR SAMPLES TO BE SENT TO MI ST COL FOR TESTS ON MILK CATTLE CTTL. CONTAMINATION OF GRIFFITH STREAM BY CHEMITROL SPRAYING FROM TRUCK CTTL. CHEMITROL CHEM HERBICIDAL POISONING CTTL. HYMAS TA CHEMI-TROL CHEMICAL COMPANY. SANFORD D S0UTHW1CK L DOW FEELS NO RELATION BETWEEN KURON WATER MIXTURE EXPOSURE AND TRACHEITIS CTTL. SORDONI CONSTRUCTION ROWE VK WALLBERG JH NUMBER DATE DOCUMENT 2183 07/09/65 AUTHOR: DON ADDRESSEE! HOSPITAL UN PA COPYEEs GORDON PJ PETERSON JE DOCUMENT 2184 08/07/62 AUTHOR: DON ADDRESSEE PETERS DJ COPYEE: COULTER LL SURGEON D DOCUMENT 2185 AUTHOR: DON ADDRESSEE: COPYEE: 05/09/56 DOCUMENT 2186 03/29/65 AUTHOR: DON ADDRESSEE: DON COPYEE: RONE VK DOEDENS JD GRANT LB HOFF RC IRISH DD PETERSON JE SMILEY RN DOCUMENT 2187 AUTHOR: DON ADDRESSEE: COPYEE 06/06/65 DOCUMENT 2188 AUTHOR: DON ADDRESSEE: COPYEE: 04/06/65 DOCUMENT 2189 AUTHOR: DON ADDRESSEE COPYEE: 04/06/65 DOCUMENT 2190 AUTHOR: DON ADDRESSEE: COPYEE: CO 03/25/65 TYPE PAGES LETTER 2 RONE VK KLIGMAN AM HOLDER BB SILVERSTEIN L LETTER 3 HAMMER OH VA ELECTRIC PON HUNT M NILTSE MG MINUTES 3 MCCOLLISTER DD MINUTES 6 SILVERSTEIN LG RONE VK AMSTUTZ FC FALSEY NP HABERSTROH W HOLDER BB LYNN GE PLETCHER DE STAEHLING EC REPORT OHARE CP 1 REPORT OHARE CP 1 REPORT OHARE CP 1 REPORT OHARE CP 1 TITLE TCDD SAMPLE AND TOXICITY INFORMATION CTTL. UNIV OF PA HOYLE HR KRAMER CG GARLON USE ON VEGETATION AT POWER DAM CTTL. VA ELECTRIC POWER MCCOLLISTER DD SCHWARTZBECK RA STATUS OF SILVEX CTTL. PAGE 311 REPORT ON THE CHLORACNE PROBLEM MEETING ON 650324. BARRONS KC FEINAUER HW HANSEN KY HOYLE NR MCCOY WJ RILEY FH TUCKER JC CORBIN WL GILL WM HARRIS JW HUTCHENREUTHER C OTIS CE SADEK SE WILTSE MG BUTYL ESTER OF 245T C10AW13). BUTYL ESTER OF 245T (10AW13). BUTYL ESTER OF 245T C10AW13). 245-TRICHLOROPHENOL (CHLOROFORM EXTRACT). NUMBER DOCUMENT 2191 AUTHOR: DON ADDRESSEE: COPYEEs DATE 09/01/65 DOCUMENT 2192 AUTHOR: DON ADDRESSEE COPYEEs 05/12/65 DOCUMENT 2193 AUTHOR: DOM ADDRESSEE? COPYEEs 00/00/65 DOCUMENT 2199 AUTHOR: DOM ADDRESSEE: COPYEEs 06/01/65 DOCUMENT 2195 08/16/56 AUTHOR: DOM ADDRESSEE: DOM C0PYEE-' KARLOVETZ F DOCUMENT 2196 09/30/55 AUTHOR: DOM ADDRESSEE: CHEMI- TROL CO COPYEE: BRYANT CA DOCUMENT 2197 08/09/55 AUTHOR: DOM ADDRESSEE COPYEE: BARRONS KC NORTON TR DOCUMENT 2198 AUTHOR: DOM ADDRESSEE DOM COPYEEs 08/03/59 TYPE PAGES REPORT OFFANE CP 1 REPORT OHARE CP 1 REPORT OHARE CP 1 REPORT OHARE CP 1 LETTER MCCOY KM ROME VK 2 LETTER ROHE VK HARLEVETZ F CONNER P 5 REPORT ROHE VK HYMAS TA MILLIAMS OJ 5 LETTER MUNSON NH ROME VK 1 i. co Eo < 245-TRICHL0R0PHEN0L (SKIN CONTACT IRRITATION). 245-TRICHLOROPHENOL CDISTILLED)(SKIN CONTACT IRRITATION). 2A5-TRICHL0R0PHEN0L (SKIN CONTACT IRRITATION). 245-TRICHL0R0PHEN0L (SKIN CONTACT IRRITATION). COMPLAINT OF FISH POND POISONING AFTER ESTERON TEN-TEN AND ESTERON 2A5 ROM SPRAYING CTTL. ESTERON BRUSH KILLER ALLEGED CASE OF LIVESTOCK POISONING CTTL. HYMAS TA INFORMATION RELATIVE TO ILLNESS TO CATTLE ON THE ALBERT SCHMUCKER FARM THREE MILES NORTH OF HARBOR BEACH, MICHIGAN. JOHNSON JE LEASURE K ALLEGED INJURY TO CATTLE FROM USE OF 2A5 BRUSH KILLER CTTL. NUMBER DATE DOCUMENT 2199 11/17/55 AUTHOR: DON ADDRESSEE: DON COPYEE: BARRONS KC DOCUMENT 2200 08/06/64 AUTHOR: DON ADDRESSEE: DON LYNCH B COPYEE: DOCUMENT 2201 09/16/54 AUTHOR: DOUGLAS CM ADDRESSEE: DOW COPYEE: DOCUMENT 2202 09/01/54 AUTHOR: DOW ADDRESSEE DOUGLAS CM COPYEE CRANDALL HA DOCUMENT 2203 08/27/54 AUTHOR: CRANDALL RA ADDRESSEE DOUGLAS CM COPYEE: RONE VK DOCUMENT 2204 07/13/54 AUTHOR: CONNER DL ADDRESSEE LAMBETH NL COPYEE: ROWE VK DOCUMENT 2205 07/12/54 AUTHOR DON ADDRESSEE: DOW COPYEE: SMITH HL DOCUMENT 2206 09/01/53 AUTHOR: DOW ADDRESSEE: CALLOWAY JB C O P Y E E : ^ RONE VK CO o < 00 TYPE PAGES MINUTES 2 LYNN GE RONE VK IRISH DD LETTER MCCOY NJ COULTER LL OCONNOR JN 1 LETTER 1 IL CNTY ELECTRI ROWE VK LETTER 1 ROWE VK IL CNTY ELECTRI SMITH HL LETTER 1 DOW IL CNTY ELECTRI LETTER 1 DON N AMERICA COMP SMITH H LETTER ROWE VK CONNER D 1 LETTER 1 WILLIAMS GJ RURAL ELECTR KY SMITH HI TITLE PAGE 313 MEMORANDUM ON CONFERENCE CONCERNING TOXICOLOGICAL WORK REQUIREMENTS FOR AGRICULTURAL CHEMICAL RESEARCH - NOVEMBER 2, 1955. JOHNSON JE THREE DEAD HOGS AFTER RIGHT OF WAY SPRAYING WITH ESTERON BRUSH KILLER CTTL. HYMAS TA ROWE VK JOHNSTON RV WILTIE M MONROE COUNTY ELECTRIC COOPERATIVE REQUESTS INFORMATION ON ESTERON BRUSH KILLER ON SKIN AND LUNG TISSUES OF HUMAN BEINGS CTTL. MONROE COUNTY ELECTRIC C STATES THAT NO COMPLAINTS HAVE BEEN RECEIVED FROM ESTERON BRUSH KILLER SPRAY DRIFT UPON SKIN AND LUNG TISSUE OF CATTLE CTTL. MONROE COUNTY ELECTRIC C REQUESTS INFORMATION ON POSSIBLE INJURIES TO SKIN AND LUNG TISSUE FROM DRIFT OF ESTERON BRUSH KILLER CTTL. MONROE COUNTY ELECTRIC 936L1690-A VAN WORMER BLACK, INC. E.W GAY - PD AUGUST, 1953. NORTH AM CO REGARDING 936L1690-A, VAN WORMER AND BLACK, INC. E.W GAY - PD, AUGUST, 1953. ASSURES OF THE SAFETY OF ESTERON BRUSH KILLER ON FISH AND LIVESTOCK BASED ON EXTENSIVE LABORATORY TESTS CTTL. FARMERS RURAL ELECTRIC C NUMBER DATE DOCUMENT 2207 07/17/53 AUTHOR: DON ADDRESSEE BARRICK FP COPYEE QUARLES JP DOCUMENT 2208 05/01/53 AUTHOR: CRAIN HD ADDRESSEE* DOW COPYEE* DIETZEL AL DOCUMENT 2209 06/25/52 AUTHOR* DOW ADDRESSEE* DOW COPYEE BRITTON JW DOCUMENT 2210 02/18/52 AUTHOR* DOW ADDRESSEE* COPYEE* ROWE VK DOCUMENT 2211 AUTHOR: DON ADDRESSEE DON COPYEE* 02/01/52 DOCUMENT 2212 10/12/59 AUTHOR* DOW ADDRESSEE: DON COPYEE* ROWE VK DOCUMENT 2213 02/13/56 AUTHOR* DOW ADDRESSEE* DOW COPYEE* FLETCHER FW DOCUMENT 2219 11/29/59 AUTHOR: DOW ADDRESSEE* DOW COPYEE* COULTER LL TYPE PAGES LETTER 1 ROWE VK CSO RAILROAD SMITH HL LETTER DON ROWE VK 1 LETTER ROWE VK SANFORD D PETERSON FC 2 ROC SIMSON HA SMITH HL 2 LETTER RONE VK SMITH HL 2 LETTER GORDON HL MILLER DN WIFFEN EE LETTER RONE VK COULTER LL 1 1 ABSTRACT WINSTON AW JOSEPHS MJ ROWE VK 1 CO o ZD. v\ TITLE PAGE 314 ASSURES THERE IS NO HAZARD TO LIVESTOCK FROM DRIFT OF DOW ESTERON BRUSH KILLER AFTER RIGHT OF WAY SPRAYING CTTL. MISSOURI STATE HIGHWAY DEPARTMENT, KANSAS CITY, MISSOURI. I DEATH OF SHEEP AND CATTLE ALLEGEDLY DUE TO BRUSH KILLER. WILLIAMS GJ PA POWER & LIGHT CO (CHEM SALESMANS CALL REPORT). RESPONSE TO INQUIRY ABOUT THE TOXICITY OF VARIOUS PRODUCTS CTTL. NO EVIDENCE THAT ESTERON BRUSH KILLER MAY CAUSE PANCREATIC TOXICITY CTTL. RECOMMEND THAT APPLICATION PROCEDURE PROPOSED SHOULD NOT BE USED BECAUSE OF POSSIBLE HEALTH HAZARDS CTTL. ONE MONTH EXPOSURE OF FISH TO M-1500 SALT. DOW DOW DOW FORMULATION OF SILVEX, SODIUM NUMBER DATE DOCUMENT 2215 11/02/62 AUTHOR: DOH ADDRESSEE COPYEE* HUNT FM ROHE VK DOCUMENT 2216 02/16/65 AUTHOR DOEDENS JD ADDRESSEE* DOH GRANT LB OTIS CE STAEHLING EC COPYEE* DOCUMENT 2217 03/02/65 AUTHOR: DOH ADDRESSEE* COPYEE* BARRONS KC DOCUMENT 2218 07/29/54 AUTHOR* ADDRESSEE* COPYEE* DOH ALLINSON RL BOUNDY RH KAGY JF MACCUTCHEON HRIGHT P SM DOCUMENT 2219 08/30/50 AUTHOR: DRILL VA ADDRESSEE: DOW BIOCHEM RES COPYEE: ALQUIST FN CRI KELLY JA TEXAS FILE A DOCUMENT 2220 AUTHOR! OLOF ADDRESSEES COPYEE 00/00/64 DOCUMENT 2221 07/13/59 AUTHOR: DOH ADDRESSEE: COPYEE: MCCOLLISTER DD TYPE PAGES REPORT HCA 1 JSM SURGEON DK LETTER DOH BAILEY C HARRIS JH RILEY FH TUCKER JC 2 TITLE VEON BK LOT 880412. DOH KOEHLINGER DG HILMETH P RITTY PM HINSTON AH PAuE 315 DECISION TO INFORM CUSTOMERS OF THE CONTAMINANTS IN TRICHLOROPHENOL COSGEN G HOFF R SILVERSTEIN L FEINAUER HH HUTCHENREUTHER CO SMILEY RN MINUTES LYNN GE CORBIN HL 2 REPORT 9 OYEN F ALQUIST FN BRITTON EC KELLY JA MCCOLLISTER DD MINUTES OF "EXCITER" PROBLEM MEETING, FEBRUARY 24, 1965. HOYLE HR RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON BUTYL (AND ISOBUTYL) A - (2,4,5-TRICHLOROPHENOXY) PROPIONATE CT25.14-236-1). BACON KD GAY HH LUCE EN SUNDERLAND HH BESHGETOOR AH GREENE LM LYNN GE HRIGHT N REPDRT 14 ACUTE AND SUB-ACUTE ORAL TOXICITY OF 245T FOR DOGS. HAYNE U MEDICIN ROHE VK BARRONS KC BOUNDY RH BRITTON EC DOSSER RC GAY HH KAGY JF LYNN GE MACCUTCHEON SM SUNDERLAND HH HESTERN CENTRAL RES FILE REPORT 6 DEFOLIATING AGENT - OUR NEH THREAT TO THE ENVIRONMENT! RESEARCH UNCERTAIN. SCIENTIFIC TRANSLATION S PROC HOLF MA RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON FORRON 245T. CO S' NUMBER DOCUMENT 2222 AUTHORi DOM ADDRESSEE COPYEEs DATE 00/00/69 DOCUMENT 2223 02/27/69 AUTHOR: DOM ADDRESSEE: COPYEE: BLAIR EH JOHNSON JE SHELDON HM DOCUMENT 2224 03/04/69 AUTHOR: KLINGMAN DL ADDRESSEE: DUNN CL COPYEE: DANIELSON LL DOCUMENT 2225 08/25/45 AUTHOR: DOM ADDRESSEE COPYEE: ADAMS M VEAZEY MR DOCUMENT 2226 08/23/50 AUTHOR: DOM ADDRESSEE: COPYEE: ALLEN MM HAUS DM SUNDERLAND MM DOCUMENT 2227 00/00/57 AUTHOR: ARCH KLIN EXP ADDRESSEE: COPYEE-' DOCUMENT 2228 00/00/50 AUTHOR DOW ADDRESSEE: COPYEE: MCCOLLISTER DD TYPE REPORT PAGES 1 SPEC 1 GOMELL JH LINDSAY D WILLIAMS RT LETTER USDA HER RADELEFF 20 REPORT GEISEL C ALLEN MM 9 REPORT ROME VK BRITTON JM IRISH DD 7 NEWS SCHULZ KH 9 REPORT ROME VK SPENCER HC 4 CO TITLE PAGE PRESENCE OF CHLORACNEGEN AND TCDD IN 245T FROM VARIOUS MANUFACTURERS. 316 SALES SPECIFICATION 245T. HAYS HN LYNN GE . HOLDEMAN GE NAEGELE RE DISCUSSION OF THE AMOUNT OF SILVEX THAT HILL BE REQUIRED TO ACHIEVE THE CONCENTRATIONS REQUIRED IN THE FEEDING STUDIES. TOXICITY OF 245T. CG ROHE VK RESULTS OF TOXICOLOGICAL TESTS ON 245T. DOSSER RC KAGY JF DUTTON HC LYNN GE CLINICAL AND EXPERIMENTAL INVESTIGATIONS CONCERNING THE ETIOLOGY OF CHLORACNE (ARCH KLIN EXP DERM 206, 589-596). THE ACUTE ORAL TOXICITY OF 245T TO RATS, MICE, GUINEA PIGS AND CHICKS. h h ( NUMBER DOCUMENT 2229 AUTHOR: DON ADDRESSEE: DON COPYEE DATE 03/15/95 DOCUMENT 2230 10/26/59 AUTHOR: DON ADDRESSEE COPYEE OYEN F DOCUMENT 2231 AUTHOR: DON ADDRESSEE: DON COPYEE 03/29/59 DOCUMENT 2232 09/27/59 AUTHOR: DON ADDRESSEE* COPYEE MCCOLLISTER DD DOCUMENT 2233 10/26/59 AUTHOR: ADDRESSEE COPYEE DON ALQUIST FN DOSSER RC LYNN GE SUNDERLAND NN DOCUMENT 2239 11/19/61 AUTHOR: DON ADDRESSEE COPYEE MCCOLLISTER DD DOCUMENT 2235 AUTHOR: DON ADDRESSEE COPYEE: DUNN L 03/05/69 DOCUMENT 2236 AUTHOR: DON ADDRESSEE' DON COPYEE 08/23/61 TYPE PAGES REPORT GEISEL C ALLEN NN 10 REPORT 13 MCCOLLISTER DD RONE VK LETTER LYNN GE RONE VK 1 REPORT NHITE L RONE VK 1 REPORT 12 MCCOLLISTER DD BARRONS KC GAY HH MACCUTCHEON SM REPORT OYEN F 21 AUTH MCCOY NJ RONE VK LETTER LYNN GE ROWE VK 1 1 TITLE TOXICITY OF 2A5T. ROWE VK VEAZEY WR PAGE 317 RESULTS OF ACUTE AMD SEMI-CHRONIC ORAL TOXICITY TESTS WITH RATS FED "SILVEX," OR 2A5TP. RECOMMENDS 245TP FEEDING TESTS TO DETERMINE CHRONIC TOXICITY RELATIVE TO USE ON RICE CTTL. 295TP. RESULTS OF ACUTE AND SEMI-CHRONIC ORAL TOXICITY TESTS WITH RATS FED "SILVEX" OR 245TP. BOUNDY RH KAGY JF OYEN F BRITTON EC KELLY JA ROWE VK SUMMARY OF PATHOLOGY ON ANIMALS FED DOWANOL ESTER OF 2A5T IN THE DIET FOR 90 DAYS. BUTOXY ETHANOL ESTER-2A5T ACID. STAGE FILE - SILVEX. NUMBER DATE \ DOCUMENT 2237 06/22/61 AUTHOR KLAUDER JV ADDRESSEE DOW COPYEE DOCUMENT 2238 06/09/61 AUTHOR KLAUDER JV ADDRESSEE DOW COPYEE DOCUMENT 2239 05/22/61 AUTHOR KLAUDER JV ADDRESSEE DOW COPYEE DOCUMENT 2240 05/12/61 AUTHOR DOW ADDRESSEE KLAUDER JV COPYEE DOCUMENT 2241 05/03/61 AUTHOR KLAUDER JV ADDRESSEE DOW COPYEE DOCUMENT 2242 AUTHOR DOW ADDRESSEE DOW COPYEE 04/05/61 DOCUMENT 2243 04/11/61 AUTHOR DOW ADDRESSEE DOW COPYEE JOHNSON JE DOCUMENT 2244 04/24/61 AUTHOR DOW ADDRESSEE KLAUDER JV COPYEE DOCUMENT 2245 07/06/59 AUTHOR' OYEN F ADDRESSEE COPYEE MCCOLLISTER DD TYPE REPORT ROWE VK PAGES 2 REPORT ROWE VK 1 REPORT ROWE 1 LETTER ROWE VK 1 LETTER ROWE VK 1 LETTER ROWF VK LYNN GE 1 LETTER LYNN GE ROWE VK LEASURE JK LETTER ROWE VK 1 1 REPORT 15 CO TITLE PAGE REPORTS FINAL RESULTS OF KUROSAL SL SKIN TESTS CTTL. 318 KUROSAL SL SKIN APPLICATIONS CTTL. KUROSAL SL PATCH TEST STUDY CTTL. KUROSAL SL IRRITATION STUDY CTTL. KUROSAL SL SKIN STUDIES CTTL. 2A5TP SKIN SENSITIZATION STUDIES DONE ON HUMANS CTTL. REQUESTS KUROSAL SL SAMPLE FOR HUMAN SKIN SENSITIZATION STUDIES CTTL. RITTY PM VANVALKENDURG JH KUROSAL SL SKIN IRRITATION 8 SENSITIZATION STUDIES CTTL. SUMMARY OF PATHOLOGY ON MALE AND FEMALE RATS FED DOWANOL 97B ESTER OF SILVEX IN THE DIET FOR THREE MONTHS. NUMBER DATE DOCUMENT 2246 11/05/59 AUTHOR ADDRESSEE COPYEE DOW BARRONS K GAY HH HYMAS TA LUCE EN PERKINS RD DOCUMENT 2247 AUTHOR DOM ADDRESSEE COPYEE AJM EHB JFK LEM PR TAH 12/27/60 DOCUMENT 2248 02/27/61 AUTHOR DOH ADDRESSEE DOM COPYEE* DOSSER RC DOM DOCUMENT 2249 AUTHOR DOM ADDRESSEE DOM COPYEE* 08/18/61 DOCUMENT 2250 04/26/62 AUTHOR ADDRESSEE* COPYEE* IND BIOTEST BARRONS K COLBY RH GREENE LM KILIAN DJ MCINTYRE HH TISDALE ML LAB DOCUMENT 2251 03/04/69 AUTHOR KLINGMAN DL ADDRESSEE DUNN CL COPYEE* DANIELSON LL "ft. C O -t TYPE PAGES REPORT LOCKWOOD DT BOUNDY RH GREENE LM JONES GD LYNN GE STENGER VA REPORT JOSEPHS MJ AMS GEL JS LJL RGH TRW 15 LETTER LYNN GE ROHE VK JOHNSON JE 1 AUTH ROHE VK LYNN GE 1 REPORT 69 KAY JH BOUNDY RH DOSSER RC HART A LUCE EN NASH HA VANVALKENBURGI W LETTER 2 USDA AR HERCULES INC RADELEFF R TITLE PAGE 319 RESULTS OF 90 DAY DIETARY FEEDING STUDIES OF DOWANOL 97B ESTER OF SILVEX (KURON) TO RATS. COLBY RW HAMMER OH KAGY JF MCCOLLISTER DD TISDALE WL ELSHERE D HART A KILIAN DJ MCINTYRE HH WRIGHT N POTASSIUM SALT OF SILVEX FOR AQUATIC WEED CONTROL. CED CWH JAK JEJ JWV KCB LLC OHH RPP RWC VKR WRM REQUEST FOR MORE TOXICITY TESTS CTTL. SOUTHWICK L VANVALKENBURG W PROPYLENEGLYCOL ISOBUTYL ETHER ESTER OF SILVEX. REPORT TO DOW CHEMICAL COMPANY 90-DAY SUBACUTE ORAL TOXICITY OF DOWCO 171 ALBINO RATS. DOW IND BIO TEST LAB BROWN R FALKENSTEIN WJ JONES GD LYNN GE PERKINS RP WRIGHT N CALENDRA JC GAY HH KAGY JF MCCOLLISTER DD SHRADER SA DOW CONSIDERATION OF MOSITURE PERCENTAGE IN HAY NECESSARY TO CORRECTLY CALCULATE MG PER KG SILVEX CTTL. NUMBER DATE DOCUMENT 2252 05/24/68 AUTHOR! DOW ADDRESSEE CORNELL UNIV COPYEE CLARK DE DOCUMENT 2253 06/06/68 AUTHOR CORNELL UNIV ADDRESSEE DOM COPYEE CLARK DE DOCUMENT 2254 08/20/65 AUTHOR DOM ADDRESSEE DOM COPYEE! GOMELL JH DOCUMENT 2255 AUTHOR: DOM ADDRESSEE COPYEE BAILEY LUECK 03/11/65 DOCUMENT 2256 10/24/67 AUTHOR DOM ADDRESSEE PROCTOR&GAMBLE COPYEE: ROME VK DOCUMENT 2257 00/00/57 AUTHOR: DOM ADDRESSEE DOM COPYEE DAVIDSON JH DOCUMENT 2258 00/00/67 AUTHOR DOM ADDRESSEE DOM COPYEE: BURGER EJ ROBINSON VB DOCUMENT 2259 AUTHOR: ADDRESSEE COPYEE: 03/01/65 TYPE PAGES LETTER 2 LENG ML STJOHN LE GETZENDANER ME LETTER LISK DJ LENG ML EPAPA 1 LETTER LYNN GE ROME VK LOUIE 1 REPORT 17 SILVERSTEIN L GOERGEN SCULAT LETTER OLSON KJ SNYDER FH 2 PRESENT 17 NORRIS JM NESSEL M REPORT 4 JOHNSON JE ROME VK REPORT 2 - C O TITLE AGE QUESTIONS CALCULATION OF THE AMOUNT OF SILVEX EXCRETED IN METABOLISM STUDY CTTL. 320 LISK DJ MCCOLLISTER DD LETTER OF APOLOGY FOR MISTAKE IN CALCULATING PERCENT SILVEX EXCRETED IN COM FEEDING STUDY CTTL. GETZENDANER ME MCCOLLISTER DD REQUEST FOR SKIN TOXICITY TESTS IN RESPONSE TO CUSTOMER COMPLAINT OF SKIN RASH WHEN USING A 2PR0DUCT MIXTURE CTTL. DON DOM HILTSE MG DOM THE CHLORACNE PROBLEM - BIOCHEM'S CONTRIBUTION. HUTCHENREUTHER STAEHLING KELLY J RESPONSE TO QUESTIONS ON ACNEGENS AND LABORATORY METHODS CTTL. TOXICOLOGY STUDIES ON CHLORINATED DIBENZO-P-DIOXINS IN LABORATORY ANIMALS DRAFT PREPARED AT THE REQUEST OF COUNSEL FOR THE PURPOSE OF HEARING PREPARATION. TCDD SINGLE DOSE ORAL TOXICITY. LYNN GE MCCOLLISTER DD TRICHLOROPHENOL SUMMARY Ul DOCUMENT 260 08/27/50 AUTHOR DOM ADDRESSEE COPYEE ALLAN MW DUTTON WC DOCUMENT 2261 01/17/56 AUTHOR DOM ADDRESSEE COPYEE ALLINSON RL BOUNDY RH GAY HH KAGY JF MCCOLLISTER DD DOCUMENT 2262 06/22/61 AUTHOR KLAUDER JV ADDRESSEE DOM COPYEE LENG ML DOCUMENT 2263 06/17/65 AUTHOR DOM ADDRESSEE DOM COPYEE BAUMAN WC DOCUMENT 2264 12/22/64 AUTHOR DOM ADDRESSEE COPYEE' COULTER KE GREENE LM KALLOS GJ SAUERS RC THORSBERG TF DOCUMENT 2265 05/04/65 AUTHOR DOM ADDRESSEE DOW COPYEE BAUMAN WC U ._ Cj REPORT 6 ROME VK BARRONS KP IRISH DD REPORT 9 TORKELSON TR ALQUIST FN BRITTON EC GREENE LM KILIAN DJ MCCUTCHEON SM REPORT 2 ROWE VK AUTH MONROE E GREENE LM KOERKER FM 2 REPORT 7 GILL HH ERBLE R HABERSTROH WH KEY M SHRADER SA NIDIGER AH AUTH 2 MONROE E GREENE LM GILL HH " f l h h. 03 RE. TS OF RANDOM FINDING TOXICOLOGICAL TESTS ON THE t. .ED AMYL ESTER OF 245T. BRITTON JW KAGY JF DOSSER RC LYNN GE RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON 4-(2,A,5-TRICHL0R0PHEN0XY) BUTYRIC ACID. BEGIN L COLBY RW HART A LUCE EN SUNDERLAND WW BESHGETOOR AH ELSHERE D HOYLE HR LYNN GE WRIGHT N KUROSAL SL PATCH TEST SHOWED NO PRIMARY IRRITANT, FATIGUEING, OR ALLERGENIC ACTION CTTL. DOW THE ANALYTICAL METHOD, THE DETERMINATION OF TCDD IN 2A5T BY GAS LIQUID CHROMATOGRAPHY, IS APPROVED FOR OUTSIDE DISTRIBUTION CTTL. WOLF M THE ANALYSIS OF CAUSTIC INSOLUBLE OILS AND PROCESS SAMPLES FROM THE 2A5-TRICHL0R0PHEN0L PROCESS FOR COMPOUNDS CAPABLE OF CAUSING CHLOROACNE, PRINCIPALLY TCDD ARW.6A.6. ERLEY DS HOLMES RD LUCE KN SILVERSTEIN L WRIGHT N GOERGEN GG HOYLE HR OLSON KJ SKELLY NE THE DETERMINATION OF COMPOUNDS CAPABLE OF CAUSING CHLORACNE IN 2A5-TRICHLOROPHENOL PROCESS SAMPLES BY GLC (ROUTING SHEET FOR THE RELEASE OF TECHNICAL INFORMATION AND LETTER OF APPROVAL) CTTL. KOERHER FW NUMBER DOCUMENT 2266 AUTHOR DOW ADDRESSEE: COPYEE DATE 04/07/65 TYPE TEST GILL HH PAGES 5 DOCUMENT 2267 00/00/65 AUTHOR DOW ADDRESSEE* COPYEE* COULTER LL MURPHY A CHART LENG ML HAMAGUCHI H 1 DOCUMENT 2268 03/10/65 AUTHOR: DOW ADDRESSEE COPYEE AMSTUTZ F KELLY J SCULATTI REPORT 17 SILVERSTEIN L BAILEY LUECK AF SHANNON DOCUMENT 2269 AUTHOR: DOW ADDRESSEE: COPYEE 04/17/78 TEST 14 DOCUMENT 2270 07/08/63 AUTHOR IND BIOTEST LAB ADDRESSEE: DOW COPYEE* REPORT KAY JH 6 DOCUMENT 2271 01/08/63 AUTHOR* HILL TOP RES INST ADDRESSEE: DOW COPYEE REPORT 8 DOCUMENT 2272 00/00/78 AUTHOR: HARRIS MW NIEHS ADDRESSEE: COPYEE* REPORT HASEMAN JK 22 ?> h h DOCUMENT 2273 01/00/79 AUTHOR* GIVAUDAN RES SAMBETH J ADDRESSEE: COPYEE. ^ CO REPORT 81 HOFFMAN LAROCHE WIPF H TITLE PAGE 322 THE DETERMINATION OF COMPOUNDS CAPABLE OF CAUSING CHLOROACNE .(CHLORACNE) IN 245-TRICHL0R0PHEN0L PROCESS MLW 64.19. SUMMARY OF TOXICOLOGICAL DATA ON SILVEX IN RATS AND DOGS. DON JANTZ OK MCCOLLISTER DD EARLY DOW HISTORY OF THE CHLORACNE PROBLEM-BIOCHEM'S CONTRIBUTION. GOERGEN LYNN GE STAEHLING EC HUTCHENREUTHER CO SCULATI ANALYTICAL METHOD TORDON 155 MIXTURE HERBICIDE (METHOD 87125B). HUMAN REPEATED INSULT PATCH TEST ON TORDON 22K. QUACK BM REPEATED INSULT PATCH TEST OF M-2431 AND THREE OTHER UNRELATED MATERIALS. THE COMPARATIVE TOXICITY OF CHLORINATED DIBENZO-P-DIOXINS IN MICE AND GUINEA PIGS (TOX AND APPLIED PHARMACOLOGY 44, 335-356). MCCONNELL EE MOORE JA THE SEVESO ACCIDENT ITS NATURE, EXTENT AND CONSEQUENCES. HOMBERGER E REGGIANI G NUMBER DATE DOCUMENT 2274 00/00/00 AUTHOR NH COALTN ALT PEST ADDRESSEE COPYEE TYPE PROMO PAGES 2 DOCUMENT 2275 06/17/79 AUTHOR HORNBLOWER M ADDRESSEE COPYEE NEWS 1 LA TIMES WA POST DOCUMENT 2276 06/24/80 AUTHOR LOS ANGELES TIMES ADDRESSEE COPYEEi DOCUMENT 2277 AUTHOR ADDRESSEE COPYEE 10/26/66 NEWS TAYLOR RB CHART 1 4 DOCUMENT 2278 AUTHOR USDA ADDRESSEE COPYEE 00/00/78 REPORT 5 DOCUMENT 2279 00/00/57 REPORT 5 AUTHOR KIMMIG J ADDRESSEE COPYEE DOCUMENT 2280 00/00/00 AUTHOR CROW KD ADDRESSEE COPYEE DOCUMENT 2281 06/12/79 AUTHOR SEARS JG ADDRESSEE SCHROETER RH COPYEE SCHULTZ KH REPORT LETTER DOW LAFOLLETTE 3 1 CO 00 hibb( TITLE BOYCOTT DOM (NM COALTN ALT TO PEST). PAGE 323 ENVIRONMENTAL FORCES GROM, GAIN STRENGTH (THE SUNDAY OREGONIAN, A13). SERVICE STATE MARNING ON 2AD HERBICIDE EXPOSURE ISSUED (LOS ANGELES TIMES). CHROMATOGRAMS FROM SILVEX DETERMINATIONS CTTL. VEGETATION MANAGEMENT MITH HERBICIDES; PACIFIC NORTHMEST REGION FOREST SERVICE, USDA, VOL 1 (TOXICITY OF TCDD). OCCUPATIONAL ACNE SO CALLED CHLORACNE DUE TO CHLORINATED AROMATIC CYCLIC ETHERS (DERMATOLOGICA 115 5A0-546, GERMAN)(TRANSLATED FOR THE TRANSLATION BRANCH TECHNICAL SERVICES DIVISION SCHOOL OF AEROSPACE MEDICINE, BROOKS AFB, TX). DR CRON'S RESULTS OF STUDIES. FINAL DOCUMENTS IN RESPONSE TO SHOECRAFT REQUEST CTTL. NUMBER DATE DOCUMENT 2282 06/07/79 AUTHOR: SEARS JG ADDRESSEE* SCHROETER RH COPYEE* DOCUMENT 2283 00/00/79 AUTHOR* TAYLOR JS ADDRESSEE* COPYEE* DOCUMENT 2284 AUTHOR: DOW ADDRESSEE COPYEE* 07/09/75 DOCUMENT 2285 AUTHOR: DOW ADDRESSEE COPYEE 02/00/53 DOCUMENT 2286 AUTHOR: DOW ADDRESSEE COPYEE: 02/00/53 DOCUMENT 2287 AUTHOR* DOW ADDRESSEE* COPYEE* 07/00/64 DOCUMENT 2288 AUTHOR* DOW ADDRESSEE COPYEE* 07/00/66 DOCUMENT 2289 AUTHOR: DOW ADDRESSEE COPYEE: 11/00/67 DOCUMENT 2290 AUTHOR* DOW ADDRESSEE* COPYEE* DOW 03/00/66 TYPE PAGES LETTER DOM LAFOLLETTE 2 REPORT 7 CLEVELAND CLINIC SPEC 1 LABEL 1 LABEL 1 LABEL DOW 4 LABEL DOM 4 LABEL DOW 2 LABEL 1 MCINTYRE HH TITLE BILLIE SHOECRAFT ENVIRONMENTAL CHLORACNE UPDATE AND OVERVIEW. FOUND 24D (SALES SPECIFICATION 20683). BRUSH KILLER 50-50. BRUSH KILLER T. ESTERON BRUSH KILLER O.S. ESTERON BRUSH KILLER O.S. MICHIGAN BK 1 BRUSH KILLER. SILVEX. PAGE 32A lhh tf NUMBER DATE DOCUMENT 2291 01/00/72 AUTHOR'- ATKINS LM WALKER EM JR ADDRESSEE: COPYEE* DOCUMENT 2292 AUTHOR: DOW ADDRESSEE COPYEE 00/00/50 DOCUMENT 2293 08/23/71 AUTHOR BRADY TP RAINS RC ADDRESSEE COPYEE DOW BOWMAN CW DEMOTT DN FREVEL LK GUM WF HOYLE HR KELLY ME MCCOY CE NUMMY WR PRUITT ME SHADOFF LA STEHL RH DOCUMENT 2293 10/13/71 AUTHOR: DOW ADDRESSEE: COPYEE DOW BREDEWEG RA FAUVER VA JEZIC Z LANGER HG MCGEE TW NORRIS JM PIPER WN ROSE JQ SHADOFF LA STEHL RH ^ VANREMOORTERE FP CO ro o TYPE PAGES REPORT 6 GADSDEN RH REPORT 5 MCCOLLISTER DD REPORT BRIGGS PR 50 AERSTIN FG COKER WP DONALDS JE GASKA RA HAKE CL JOHNSON NE LAKE DE MOSS RD OSBORNE DW PUMPELLY CT SHEETZ DP TREE RM ABSTRACT 1 ENS LA BLAIR EH BRIGGS PR GEHRING PJ JOHNSON JE LYNN GE MUELDER WW NORTH PP PUMPELLY CT ROWE VK SHEETZ DP STRUTHERS JA WILKE E TITLE PAGE 325 SOME EFFECTS OF 24D AND 245T ON EHRLICH ASCITES TUMOR CELLS IN VIVO AND IN VITRO (IND MEDICINE 41(1), 22-27). GALE GR MEDICAL UNIV OF SC THE ACUTE ORAL TOXICITY OF 245T TO RATS, MICE, GUINEA PIGS AND CHICKS. ROWE VK SPENCER HC THERMAL CHEMISTRY OF 24D AND 245T (NVA-16KCRI 713986). DOW LANGER HG BLAIR EH CRUMMETT WB ENGIBOUS DL GEHRING PJ HINMAN CW JOHNSON RL LEAVITT FC MUELDER WW PETERSON LI ROWE VK SILVERSTEIN LG WHITE HC BLUE RD DELINE DD FERNANDEZ JB GILL HH HOUTMAN T KEITH JR LYNN GE NAEGELE RE PLEPYS RA SEIDEL EM SNYDER RE ORIGIN AND FATE OF THE CHLORODIOXINS, ABSTRACTS FROM A SYMPOSIUM AT THE 162ND NATIONAL ACS MEETING, WASHINGTON, D.C., 710916 TO 710917 (OC 710005-3)(715305). PIERCE JK BOER FP CRUMMETT WB GLEDHILL JR JOHNSON RL MAROUCHOC SR NELSON DA PAPENFUSS RR RINN HW SCHWETZ BA SNYDER RE THEIS JM WOODWARD RE BRADY TP DALMAN GW GUM WF KEITH JR MATALON R NEUMANN MA PETERSON LI ROBERTS RW SEIDEL EM SPARSCHU GL TREE RM YOUNG AE NUMBER DOCUMENT 2295 DATE 10/13/71 AUTHOR* DOH ADDRESSEE* COPYEE* DOH FAUVER VA LANGER HG PIPER HN YOUNG AE DOCUMENT 2296 06/27/73 AUTHOR* DOH ADDRESSEE* EPA COPYEE* DOH MCCOLLISTER DD DOCUMENT 2297 00/00/00 AUTHOR* ADDRESSEE* COPYEE* DOCUMENT 2298 00/00/00 AUTHOR* ADDRESSEE* COPYEE* DOCUMENT 2299 AUTHOR* DOH ADDRESSEE* COPYEE* DOCUMENT 2300 AUTHOR* DOH ADDRESSEE* COPYEE* DOCUMENT 2301 AUTHOR* DOH ADDRESSEE* COPYEE* 08/00/67 00/00/00 07/00/65 TYPE REPORT PAGES 16 ENS LA BLAIR EH GEHRING PJ MUELDER HH ROHE VK LETTER MULLISON HR MOUNTFORT RF FLANNERY RF MCCUTCHEN LR 2 MEMO 1 LEGAL MEMO LABEL LABEL LABEL 8 2 2 A IXbWG w ro TITLE PAGE 326 ORIGIN AND FATE OF THE CHLORODIOXINS, ABSTRACTS FROM A SYMPOSIUM AT THE 162ND NATIONAL ACS MEETING, WASHINGTON, D.C., 710916 TO 710917 (OC 710005-3H715305). PIERCE JK BOER FP JOHNSON JE PAPENFUSS RR SPARSCHU GL CRUMMETT WB JOHNSON RL PETERSON LI STEHL RH KURON WEED AND BRUSH KILLER, EPA REG 464-162, YOUR LETTER OF 730501. KENAGA EE SOUTHWICK L LENG ML COLOR SLIDE PRINTS TAKEN BY DOCTOR WAYNE BINNS DURING INSPECTION IN FEBRUARY, 1970 (700200) AT HERBICIDE SPRAY PROJECT AREA NEAR GLOBE, AZ. COLOR SLIDE PRINTS OF BILLIE AND WILLARD SHOECRAFT PROPERTY ON ICE HOUSE CANYON ROAD SOUTH OF GLOBE, AZ (TAKEN BY DOCTOR CHESTER R LEATHERS ON DATES INDICATED. KURON (WEED AND BRUSH KILLER). ESTERON 99 (CONCENTRATE WEED KILLER). KURON BRUSH KILLER. NUMBER DOCUMENT 2308 DATE 05/13/75 AUTHOR: DOW ROSE JQ ADDRESSEE COPYEE: DOW FREVEL LK KILIAN DJ MCCOLLISTER DD PULLIN T DOCUMENT 2309 04/20/71 AUTHOR: DOW ADDRESSEE COPYEE: DOW BLAIR EH GORDON HL JOHNSON JE MCCOLLISTER DD ROWE VK DOCUMENT 2310 02/09/76 AUTHOR: BLAU GE LEBEAU JE ADDRESSEE COPYEE BRAUN WH SAUERHOFF MW DAVIDSON JH GORDON HL HEFNER RE JENSEN DJ KOCIBA RJ MCKENNA MJ OLSON KJ RAMPY LW SCHARNWEBER HC SOUTHWICK L WATANABE PG DOCUMENT 2311 12/11/70 AUTHOR ANILINE 0 ADDRESSEE COPYEE: ANILINE 0 BURGERT BE GORDON HL KILIAN DJ MCCOLLISTER DD ROBINSON VB IO ro TYPE REPORT PAGES 48 GEHRING PJ WENT2LER TH BLAIR EH GORDON HL RIMMEL CE MOOLENAAR RJ RINZEMA L REPORT GEHRING PJ GEHRING PJ BURGERT BE GORING CA KILIAN DJ MCINTYRE MM SCHWARZ AJ 1 REPORT 19 BRAUN WH SAUERHOFF MW DOW BLAIR EH DISHBURGER HJ GORING CA HINMAN CW JERSEY GC LANGNER R MULLISON WR OLSON RD RAMSEY JC SCHOBER AE SWANK MG WATSON AJ REPORT DOW DOW CLEGG DH GORING CA KIMMEL CE MCINTYRE HH SCHWARZ AJ 1 TITLE PAGE 328 THE FATE OF TCDD FOLLOWING SINGLE AND REPEATED ORAL DOSES TO THE RAT (NBK 110KPRESENTED TO SOCIETY OF TOX, FOURTEENTH ANNUAL MEETING, 750300, WILLIAMSBURG, VA). HUMMEL RA RAMSEY JC BURGERT BE HOLDER BB LEAVITT FC OLSON RD ROBINSON VB CARLETON RE HORVATH B MACCUTCHEON SM PRUITT ME SHAVER RJ CHLORACNE STUDY CONDUCTED ON TCDD (NB T36 25-66681-17HCRI 71-1805) NORRIS JM NORRIS JM EDWARDS H HOLDER BB KIMMEL CE PITCHFORTH L SILVERSTEIN L AXE ED FREVEL LK HORVATH B MACCUTCHEON SM ROBINSON VB THE FATE OF 24D FOLLOWING ORAL ADMINISTRATION TO MAN(K-002372). DOW GEHRING PJ GEHRING PJ BROWN S FIKE R GROVES KO HOYLE HR JOHNSTON CV LENG ML MURRAY FJ PULLIN T RAPP DE SCHWETZ BA THOMPSON CF WOLF MA LEBEAU JE DANIEL RL GETZENDANER ME HEEG JF HUMISTON CG KILIAN DJ MCCOLLISTER DD NORRIS JM QUAST JF ROWE VK SCORY LK TORKELSON TR YOUNG JD CHLORACNE STUDY CONDUCTED ON HEXACHLORODIBENZO-P-DIOXIN (BC T 3 6 .25-84763-3). GEHRING PJ NORRIS JM BARTON J EDWARDS H HOLDER BB LLOYD BH MORSE D BLAIR EH FREVEL LK JOHNSON JE MACCUTCHEON SM PITCHFORTH L NUMBER DATE DOCUMENT 2312 11/03/70 AUTHOR * ANILINE 0 ADDRESSEE COPYEE ANILINE 0 BURGERT BE GORDON HL KILIAN DJ MCCOLLISTER DD ROBINSON VB DOCUMENT 2313 09/10/70 AUTHOR DOW ADDRESSEE COPYEE DOW BURGERT BE GORDON HL KILIAN DJ MCCOLLISTER DD ROBINSON VB DOCUMENT 2314 11/04/70 AUTHOR ANILINE 0 ADDRESSEE COPYEE ANILINE 0 BURGERT BE FREVEL LK JOHNSON JE MACCUTCHEON SM PITCHFORTH BH DOCUMENT 2315 02/19/71 AUTHOR DOW ADDRESSEE DOW KRAMER CG COPYEE DOCUMENT 2316 09/02/70 AUTHOR* DOW BOURNE JE ADDRESSEE COPYEE BOURNE JE NORRIS JM TYPE PAGES REPORT 1 DOW DOW CLEGG DH GORING CA KIMMEL CE MCINTYRE HH SCHWARZ AJ REPORT GEHRING PJ PLEPYS RA CLEGG DH GORING CA KIMMEL CE MCINTYRE HH SCHWARZ AJ 1 REPORT 1 DOW DOW CLEGG DH GORDON HL KILIAN DJ MCCOLLISTER DD ROBINSON VB LETTER GEHRING PJ GORDON HL ROWE VK 1 REPORT VK GEHRING PJ GEHRING PJ SHADOFF L 25 U bh'd CO to CO TITLE PAGE 329 CHLORACNE STUDIES CONDUCTED ON HEXACHLORODIBENZO-P-DIOXIN (BC T36.25-89763-2). GEHRING PJ NORRIS JM BARTON J EDWARDS H HOLDER BB LLOYD BH MORSE D BLAIR EH FREVEL LX JOHNSON JE MACCUTCHEON SM PITCHFORTH L CHLORACNE STUDIES CONDUCTED ON HEXACHLORO-DIBENZO-P-DIOXIN (BC T36.25-89763-1). NORRIS JM PLEPYS RA BARTON J EDWARDS H HOLDER BB LLOYD BH MORSE D BLAIR EH FREVEL LK JOHNSON JE MACCUTCHEON SM PITCHFORTH L ACUTE ORAL LETHALITY AND CHLORACNE STUDIES CONDUCTED ON OCTOCHLORODIBENZO-P-DIOXIN (BC T36 25-59762-9). GEHRING PJ NORRIS JM BARTON J EDWARDS H GORING CA KIMMEL CE MCINTYRE HH ROWE VK BLAIR EH FERNANDEZ JB HOLDER BB LLOYD BH MORSE D SCHWARZ AJ SUGGESTED PROTOCOL FOR THE CONSUMPTION OF 29D AND 295T CTTL. HINMAN CW JOHNSON JE TCDD. DOW NORRIS JM KOCIBA RJ SPARSCHU GL SPARSCHU GL MUELDER WW oehh`(X NUMBER DATE DOCUMENT 2317 08/20/79 AUTHOR DOM SHARMA RP SCHWEIZ BA ADDRESSEE COPYEE DOM BARNARD S BUREK JD DELINE DD HEFNER RE JOHNSON RL LENG ML NORRIS JM RINZEMA LC THOMPSON DJ WATANABE PG DOCUMENT 2318 08/20/79 AUTHOR ADDRESSEE COPYEE DOM SHARMA RP SCHWEIZ B DOM BARNARD S BUREK JD DELINE DD HEFNER RE LANGNER RR MANSTON J OLSON RD ROME VK TRAYNOR MJ DOCUMENT 2319 02/27/78 AUTHOR ADDRESSEE COPYEE* W ro BLOGG CD MURRAY FJ SMITH FA BLOGG CD MURRAY FJ BARNARD S DAVIDSON JH GEHRING PJ HENRY H KOCIBA RJ LENG ML MURRAY JS PILNY MK SCHARNWEBER HC ULRICH JR TYPE PAGES REPORT GEHRING PJ SHARMA RP DOW GEHRING PJ BETSO JE CRUMMETT MB DISHBURGER 1 HENRY H LANGNER RR MANSTON J OLSON RD ROME VK TRAYNOR MJ REPORT GEHRING PJ SHARMA RP DOM GEHRING PJ BETSO JE CRUMMETT MB DISHBURGER 1 HOLDER BB LAPE RL MCCOLLISTER RAMSEY JC SCHARNMEBER ULRICH JR REPORT 172 DOM NITSCHKE DD DOM RAO KS BLAIR EH DAVIS RA GETZENDANER ME HOLDER BB LANGNER RR MANSTON J NITSCHKE KD RAMSEY JC SCHLACHTER MM VERSCHUUREN HG TITLE PAGE IMMUN0T0XIC0L0GIC STUDIES INVOLVING TCDD IN MICE AND RABBITS (REPORT HET-K-66681-(36))(CRI 795145). KOCIBA RJ SCHHETZ BA KOCIBA RJ GEHRING PJ 330 KOCIBA RJ BLAIR EH DAVIDSON JD GETZENDANER ME HOLDER BB LAPE RL MCCOLLISTER DD RAMSEY JC SCALACHTER MM ULRICH JR SCHHETZ BA BLOGG CD DAVIS RA GLEESON JG JOHNS DB LEBEAU JE NITSCHKE KD RAO KS SCHARNWEBER VRANISH SR REVERSAL OF IMMUNOLOGIC TOXICOLOGIC EFFECTS OF A SINGLE EXPOSURE OF TCDD IN MICE (R&D REPORTSK794930). KOCIBA RJ SCHHETZ BA KOCIBA RJ GEHRING PJ KOCIBA RJ BLAIR EH DAVIDSON JH GETZENDANER ME JOHNS DB LEBEAU JE NITSCHKE KD RAO KS SCHLACHTER MM VERSCHUUREN HG SCHHETZ BA BLOGG CD DAVIS RA GLEESON JG JOHNSON RL LENG ML NORRIS JM RINZEMA LC THOMPSON DJ WATANABE PG THREE GENERATION REPRODUCTION STUDY OF RATS INGESTING TCDD (R&D REPORTMHET K-66681-(29))(CRI 783984). HUMISTON CG JOHN JA RAO KS SCHHETZ BA HUMISTON CG SCHHETZ BA CRAWFORD AA DELINE DD GLEESON JG JOHNS DB LAPE RL MCCOLLISTER DD NORRIS JM RINZEMA L THOMPSON DJ WATANABE PG JOHN JA SMITH FA CRUMMETT WB DISHBURGER HJ HEFNER RE JOHNSON RL LEBEAU JE MURPHY PM OLSON RD ROWE VK TRAYNOR MJ NUMBER DATE DOCUMENT 2320 00/00/73 AUTHOR DOW NORRIS JM ADDRESSEE COPYEE DOCUMENT 2321 09/00/73 AUTHOR DOW NORRIS JM ADDRESSEE COPYEE DOCUMENT 2322 00/00/73 AUTHOR DOW ROWE VK ADDRESSEE COPYEE, DOCUMENT 2323 11/00/73 AUTHOR DOW ROWE VK ADDRESSEE COPYEE DOCUMENT 2324 01/16/76 AUTHOR DOW SMITH FA ADDRESSEE COPYEE DOW CRUMMETT WB HEFNER RE JOHNSON JE KILIAN DJ LEAVITT FC MINTZ MJ PARSEY ES ROBINSON VB THOMPSON DJ TYPE PAGES NEWS REPORT EMERSON JL ROWE VK REPORT EMERSON JL ROWE VK NEWS REPORT GEHRING PJ SCHWETZ BA REPORT GEHRING PJ SCHWETZ BA ABSTRACT GEHRING PJ BLAIR EH DAVIDSON JH HOLDER BB JOHNSON RL KIMMEL CE LENG ML MOOLENAAR RJ PRUITT ME ROWE VK WARNER SB TITLE PAGE 331 TOXICOLOGY OF CHLORINATED DIBENZO-P-DIOXINS (ADVANCES IN CHEMISTRY SERIESC120) 721024). GEHRING PJ SCHWETZ BA GERBIG CG SPARSCHU GL TOXICOLOGY OF CHLORINATED DIBENZO-P-DIOXINS (ENVIRONMENTAL HEALTH PERSPECTIVES (5), 730900). GEHRING PJ GERBIG CG SCHWETZ BA SPARSCHU GL THE FATE OF 245T FOLLOWING ORAL ADMINISTRATION TO MAN CTOX A APPLIED PHARMACOLOGY 26(3), 352-361). KRAMER CG ROSE JQ THE FATE OF 245T FOLLOWING ORAL ADMINISTRATION TO MAN (JOUR OF TOX AND APPLIED PHARMACOLOGY 26(3), 352-361). KRAMER CG ROSE JQ TERATOGENICITY OF TCDD IN CF-1 MICE(TOX RES LAB). NITSCHE KD SCHWETZ BA BURGERT BE DISHBURGER HJ HORVATH B JOHNSTON RV KOCIDA RJ LYNN GE MUELDER W PULLIN T SCHARNWEBER HC WESSEL MR CRI GORDON HL HOUSE RJ KAYE SCHOLER LANGNER RR MCCOLLISTER DD OLSON RD RINZEMA L SPENCER HC YATES WM DUMBER DATE DOCUMENT 2325 08/24/71 AUTHOR: DOW SPARSCHU GL ADDRESSEE COPYEE DOW BLAIR EH GORDON HL JOHNSON JE MCCOLLISTER DD SCHWARZ AJ DOCUMENT 2326 02/27/78 AUTHOR ' BLOGG CD KOCIBA RJ SCHWETZ BA ADDRESSEE' COPYEE BLOGG CD KOCIBA RJ SMITH FA BEARDEN CR BROWER HH CAPUTO R CRUMMETT WB DAVIS RA ENGIBOUS DL GRAHAM DL HENRY H HYDE MA JOHNSON RL KIMMEL CE LEBEAU JE MACGOWAN CF MCCOLLISTER DD MOOLENAAR RJ MURRAY N NOLAN RJ OLSON KJ PRUITT ME RAMPY LW ROBERTS DJ SCHAFFER AW SERCU CL THOMPSON DJ VERSCHUUREN HG WATANABE PG TYPE PAGES ABSTRACT 1 GEHRING PJ GEHRING PJ BURGERT BE GORING CA KII.IAN DJ MCINTYRE HH SHAVER RJ ABSTRACT 173 REPORT DOW MURRAY FJ SMITH FA DOW MURRAY FJ AXE RD BLAIR EH BUREK JD CARLETON RE DAIGRE GW DEGESERO RD GEHRING PJ GRIESS GA HOERGER FD JACKSON L JOHNSTON RV LANGNER RR LENG ML MACKEY JC MCFEDRIES R JR MOORE JH NICHOLS JL NORRIS JM OLSON RD PUMPELLY CT RAMSEY JC ROBINSON VB SCHARNWEBER HC SHAVER RJ TODD LM VRANISH SR YOCUM RH CO O 05 -c i TITLE PAGE 332 THE EFFECTS OF 24D AND ESTERS OF 24D ON RAT EMBRYONAL, FETAL AND NEONATAL GROWTH AND DEVELOPMENT. LYNN GE SCHWETZ BA LYNN GE EDWARDS H HOLDER BB KIMMEL LE PITCHFORTH L SILVERSTEIN L AXE FD FREVEL LK HORVATH B MACCUTCHEON SM ROBINSON VB WILLIAMS CS THREE GENERATION REPRODUCTION STUDY OF RATS INGESTING TCDD (HET K-66681-(29>). HUMISTON CO NITSCHKE DD JOHN JA RAO KS HUMISTON CO RAO KS BARNARD S BRAUN WH BURGERT BE CARLSON RG DANIEL RL DELINE DD GETZENDANER ME HALPHEN CE HOLDER BB JERSEY GC KELLY ME LAPE RL LIU G MANSTON J MCINTIRE OR MURPHY PM NIELSEN WH NOWAK RM PILNY MK QUAST JF REUVERS H ROGERS WA SCHLACHTER MM SHEETZ DP TRAYNOR MJ WACHOB WW YOUNG DJ JOHN JA SCHWETZ BA BEAMER WH BRUNLICH FH CALDWELL CE CRAWFORD AA DAVIDSON JD DISHBURGER HJ GLEESON JG HEFNER RE HORVATH BS JOHNS DB KILIAN DJ LEAVITT FC MAASBERG AT MCCLURE HH MCKENNA MJ MURRAY JS NITSCHKE KD NUMMY WR POTTS WJ RABOLD CP RINZEMA L ROWE VK SCHNEIDER JA THOMPSON CF ULRICH JR WARNER SD YOUNG JD bh'( NUMBER DATE DOCUMENT 2327 06/21/73 AUTHOR: DOW ADDRESSEE DOW COPYEE: GEHRING PJ DOCUMENT 2328 11/21/73 AUTHOR: DOW ADDRESSEE DOW COPYEE BLAIR EH GEHRING PJ HORVATH BS LEAVITT FC MOOLENAAR RJ ROBINSON VB DOCUMENT 2329 11/21/73 AUTHOR DOW ADDRESSEE DOW COPYEE BLAIR EH GEHRING PJ * HORVATH BS LEAVITT FC MOOLENAAR FJ ROBINSON VB DOCUMENT 2330 AUTHOR DOW ADDRESSEE DOW COPYEE 02/25/74 DOCUMENT 2331 11/21/73 AUTHOR DOW ADDRESSEE COPYEE BLAIR EH GEHRING PJ HORVATH B LEAVITT FC MCINTYRE HH RINZEMA L DOCUMENT 2332 00/00/78 AUTHOR COOK RR TOWNSEND JC ADDRESSEE COPYEE: CO CO ^3 TYPE PAGES REPORT SCHWETZ BA LENG ML NORRIS JM 2 REPORT 16 SCHWETZ BA BURGERT BE GORDON HL HOUSE RJ MACCUTCHEON SM OLSON RD SHAVER RJ ABSTRACT SCHWETZ BA 1 BURGERT BE GORDON HL HOUSE RJ MACCUTCHEON SM OLSON RD SHAVER RJ PRESENT 101 SCHWETZ BA REPORT 17 SCHWETZ BA BRGET BE GORDON HL HOUSE RJ LENG ML MOOLENAAR RJ ROBINSON VB REPORT DOW 3 TITLE LETTER REPORT LD50 OF TCDD IN GUINEA PIGS PAGE 333 ROWE VK PLACENTAL TRANSFER OF 24D AND 245T IN PREGNANT RATS. DOW EDWARDS H GORING CA KILIAN DJ MCCOLLISTER DD PRUITT ME FREVEL LK HOLDER BB KIMMEL CE MCINTYRE HH RINZEMA LC PLACENTAL TRANSFER OF 24D AND 245T IN PREGNANT RATS. DOW EDWARDS H GORING CA KILIAN D MCCOLLISTER DD PRUITT ME DOW FREVEL LK HOLDER BB KIMMEL CE MCINTYRE HH RINZEMA LC TESTIMONY FOR 2A5T HEARING TERATOGENIC POTENTIAL OF 245T AND CHLORINATED DIBENZO-P-DIOXINS. PLACENTAL TRANSFER OF 24D AND 2A5T IN PREGNANT RATS NBT 23.14-ll-(16) NBT 23.14-Z3-(Z). EDWARDS H GORING CA KILIAN DJ MCCOLLISTER DD OLSON RD SHAVER RJ FREVEL LK HOLDER BB KIMMEL CE MCCUTCHEON SM PRUITT ME MORTALITY EXPERIENCE OF EMPLOYEES EXPOSED TO TCDD. OTT MG SILVERSTEIN LG I' h'Zhh 'C NUMBER DATE DOCUMENT Z333 11/12/59 AUTHOR: ADDRESSEE COPYEE' COULTER: LL HILTON HF MONROE E DOCUMENT 2334 AUTHOR: DOM ADDRESSEE COPYEE 07/00/71 DOCUMENT 2335 AUTHOR DOM ADDRESSEE COPYEE 01/10/55 DOCUMENT 2336 AUTHOR DOM ADDRESSEE COPYEE 07/01/52 DOCUMENT 2337 00/00/00 AUTHOR DOM ADDRESSEE COPYEE: HINMAN CM DOCUMENT 2338 AUTHOR DOM ADDRESSEE COPYEE 03/27/72 DOCUMENT 2339 AUTHOR DOM ADDRESSEE COPYEE 01/08/80 DOCUMENT 2340 07/01/78 AUTHOR ADDRESSEE: COPYEE ALBRECHT KEELER P MCCOLLISTER STEARNS MJ MOODS CD DD TYPE PAGES REPORT 10 DAVIDSON JH I APF PUBLIC SERVICE REPORT JOHNSON JE 7 REPORT JOHNSON JE 6 REPORT 13 JOHNSON JE REPORT 12 JOHNSON JE TECH 2 TECH 3 AUTH TECH DOM KEENEY N MULL ISON MR TAITS SR 4 TITLE PAGE 334 PRELIMINARY OBSERVATIONS ON THE USE OF SILVEX GRANULES FOR BRUSH CONTROL ON RIGHTS OF WAY C109824). DOW HAERTL EJ I JLS JOHNSON JE SAFETY IN THE DEVELOPMENT OF HERBICIDES!DTE 27ill), 1-7). THE RESPONSE OF COTTON TO LOW RATES OF 24D, 245T, MCP AND SILVEX. WATSON AJ WEED CONTROL IN SOYBEANS (REPORT 314). LYNN GE WATSON AJ HUMAN TOLERANCE OF 24D AND 245T. ESTERON 245 BRUSH KILLER (MATERIAL SAFETY DATA SHEET). ESTERON 245 BRUSH AND WEED KILLER(PRODUCT CODE 28749MMATERIAL SAFETY DATA SHEET). ESTERON 245 BRUSH AND WEED KILLER!PRODUCT CODE 28749MMATERIAL SAFETY DATA SHEET). GOLD W KING EJ SMITH LL VACARRO J JANTZ OK LANHAM J SPF.ER LH WOLF MA NUMBER DATE TYPE PAGES DOCUMENT 2341 AUTHOR DOW ADDRESSEE* COPYEE: 04/01/78 DOCUMENT 2342 AUTHOR: DOW ADDRESSEE' COPYEE: 12/01/77 DOCUMENT 2343 03/21/79 AUTHOR: DOW ADDRESSEE ST DEPT OF AG COPYEE: DOCUMENT 2344 AUTHOR: DOW ADDRESSEE* COPYEE: 08/27/82 DOCUMENT 2345 02/09/76 AUTHOR* DOW ADDRESSEE* COPYEE* DOW GERONIMO J HEFNER RE MOSS RD WRIGHT WG DOCUMENT 2346 AUTHOR: DOW ADDRESSEE COPYEE: 05/16/73 DOCUMENT 2347 03/31/76 AUTHOR-' ADDRESSEE' COPYEE: BYRD BC GERONIMO J HEFNER RE MOSS RD RYDER JC C O WILLIAMS CS ro CO TECH 2 TECH 2 LETTER TALCOTT AT 2 TECH 1 REPORT 16 WARREN LE WILLIAMS CS GORING CA LINCE M REGAN JB REPORT 3 REPORT 11 COLBY RW GORING CA HOLMSEM TW PRUITT ME SAUNDERS ES WRIGHT WG Cbh-d TITLE PAGE 335 ESTEROH 245 BRUSH AND WEED KILLERtPRODUCT CODE 28749HMATERIAL DATA SAFETY SHEET). ESTERON 245 BRUSH AND WEED KILLERtPRODUCT CODE 28749)(MATERIAL SAFETY DATA SHEET). SUPPLEMENTAL LABELING 245T AND SILVEX PRODUCTS. EMERGENCY RESPONSE INFORMATION SHEET. ESTERON 245 BRUSH KILLER. CONTROL OF WOODY PLANT BY BASAL APPLICATIONS OF TRICLOPYR, PICLORAM AND 245T (REPORT GH-P 940)(761266). WILLIAMS CS BYRD BC GRUMBLES JB LUDWIG PD RITTY PM FEARS RD HANSON RG MCCOLLISTER DD RYDER JC ESTERON BRUSH KILLER (REGISTRATION STATUS REPORT). EVALUATION OF TORDON 155 MIXTURE AND TRICLOPYR (M-4021) APPLIED AS A BASAL APPLICATION FOR WOODY PLANT CONTROL IN WS AND MN IN 740000. DOW GRUMBLES JB LICHY CT REGAN JB SMITH LL FEARS RD HANSON RG MCCOLLISTER DD RITTY PM HARREN LE 1+ & NUMBER DATE DOCUMENT 2348 AUTHOR DOW ADDRESSEE COPYEE 03/18/78 DOCUMENT 2349 AUTHOR DOW ADDRESSEE* COPYEE: 03/22/79 DOCUMENT 2350 05/31/78 AUTHOR: CHENOWETH MB ADDRESSEE: COPYEEs DOCUMENT 2351 AUTHOR DOW ADDRESSEE COPYEE: 08/09/71 DOCUMENT 2352 03/22/76 AUTHOR DOW ADDRESSEE EPA COPYEE ROSS RT DOCUMENT 2353 08/08/81 AUTHOR: NORRIS JM KEELER P ADDRESSEE* COPYEE CALDWELL B DOCUMENT 2354 06/24/80 AUTHOR* DOW ADDRESSEE COPYEE DOCUMENT 2355 10/21/80 AUTHOR: MAYER A ADDRESSEE COPYEE: TYPE PAGES REPORT 1 FISHBECK WA REPORT 2 REPORT DOW 4 REPORT NORRIS JM 2 LETTER REPORT LENG ML MOUNTFORT RF 2 MEDREC MEMO TELECON DOW LANHAM JM LEE B REPORT TECH KEELER P 10 2 NEWS 1 EDMONTON JOUR TITLE ESTERON 2A5 BRUSH KILLER (MEDICAL INFO). KEELER P PAGE 336 ESTERON 2A5 BRUSH KILLER (EMERGENCY RESPONSE INFORMATION SHEET) ESTERON BRUSHKILLER (MEDICAL INFORMATION)(M03507). FISHBECK WA KEELER P ESTERON BRUSH KILLER M3507. PESTICIDE PETITION 8F0675 FOOD ADDITIVE PETITION 2H5001. EXPOSURE TO ESTERON 2A5 & MEDICAL INFORMATION CTTL. BLACKHURST B HEED JM ZHEIGLE R GONDEK HOYLE HR KOLESAR TOXICOLOGY ANTICIPATED HUMAN RESPONSE ESTERON 2A5 BRUSH & HEED KILLER (M 3506KMEDICAL INFORMATION). LANHAM JM FARM CHEMICALS SAFETY TESTS FAULTY (EDMONTON JOUR). NUMBER DOCUMENT 2356 DATE 00/00/79 AUTHOR* GIVAUDAN SAMBETH J ADDRESSEE* COPYEEs TYPE PAGES LEGAL AA REPORT HOFFMANN LAROCHE WIPF HK DOCUMENT 2357 10/25/80 NEWS AUTHOR! HAMILTON SPECTATOR ADDRESSEE* COPYEE STEWART B 1 DOCUMENT 2358 08/22/78 AUTHOR: ADDRESSEE* COPYEE* BRAUN WH SMITH FA BRAUN WH BLAIR EH DAVIDSON JH GEHRING PJ HENRY H JOHNS DB LEBEAU JE MCKENNA MJ OLSON RD RINZEMA L TRAYNOR MJ WATANABE PG REPORT DOW 21 DOW BUREK JD DAVIS RA GETZENDANER ME HOLDER BB JOHNSON RL LENG ML MURPHY FJ QUAST JF ROWE VK ULRICH JR YOUNG JD DOCUMENT 2359 AUTHOR* DOW ADDRESSEE* COPYEE* 01/00/80 REPORT HOLDER BB A DOCUMENT 2360 05/00/69 AUTHOR* PALMER JS ADDRESSEE* COPYEE* REPORT RADELEFF RD 8 DOCUMENT 2361 00/00/70 AUTHOR: LEA 8 FEBIGER ADDRESSEE: COPYEE: -C. SU 4331 ~4 REPORT RADELEFF RD 3 TITLE PAGE 337 THE SEVESO ACCIDENT ITS NATURE, EXTENT AND CONSEQUENCES (ANN OCCUP HYG, 22, 327-368). HOMBERGER E REGGIANI G MINISTRY TESTING DEADLY CHEMICAL FOUND IN 24D WEEDKILLER (HAMILTON SPECTATOR). TCDD TISSUE DISTRIBUTION AND EXCRETION FOLLOWING A SINGLE ORAL DOSE IN FEMALE GUINEA PIGS R&D REPORT K-66601-137 (CRI 791735). HEFNER JG NOLAN RJ NOLAN RJ CRUMMETT WB DELINE DD GLEESON JG HUMISTON CG LANGNER RR MANSTON J MURPHY PM RAMPY LW SCHARNWEBER HC VERSCHUUREN HG BARNARD S DAVIDSON JD DISHBURGER HJ HEFNER RE JERSEY GC LAPE RL MCCOLLISTER DD NORRIS JM RAMSEY JC SCHWETZ BA WARNER SD A MORTALITY ANALYSIS OF EMPLOYEES ENGAGED IN THE MANUFACTURE OF 245T (JOUR OF OCCUPATIONAL MEDICINE 22(1), 47-50). OLSON RD OTT MG THE TOXICITY OF SOME ORGANIC HERBICIDES TO CATTLE, SHEEP AND CHICKENS (PRODUCTION RES REPORT 106)(SA50.00.01.PIKPP8F0675). USDA ARS SILVEX KURON (VETERINARY TOX, 269-271)(SA50.00.01.PI). (PP8F0675). NUMBER DOCUMENT 2362 DATE 09/10/70 TYPE REPORT PAGES 18 AUTHOR* DOW ADDRESSEE* COPYEE* DOCUMENT 2363 00/00/61 AUTHOR* MONARCA G ADDRESSEE* COPYEE* DOCUMENT 2364 01/23/68 AUTHOR* KLIGMAN AM ADDRESSEE* DOW COPYEE* DOCUMENT 2365 04/23/59 AUTHOR* DOW ADDRESSEE* COPYEE* DOW COLBY RW GREENE LM JONES GD LYNN GE STENGER VA DOCUMENT 2366 12/20/57 AUTHOR* DOW ADDRESSEE* COPYEE* DOW COLBY RW GRAY HE JONES GD LYNN GE SCOLES GW DOCUMENT 2367 AUTHOR* DOW ADDRESSEE* COPYEE* 03/25/53 LENG ML REPORT DIVITO G 6 REPORT 2 U PA HOSPITAL ROWE VIC REPORT 20 WOLF MA ATHAY RM ELSHERE D HAMMER OH KAGY JF MCCOLLISTER DD TISDALE WL REPORT 9 MCCOLLISTER DD ALLINSON RL COULTER LL GRFENE LM KAGY JF MCINTYRE HH TISDALE WL TEST I HCS 21 CO CO TITLE PAGE 338 PETITION FOR THE ESTABLISHMENT OF TOLERANCES FOR THE PESTICIDE CHEMICAL 22A5-TRICHL0R0PHEN0XY) PROPIONIC ACID ON RAW AGRICULTURAL COMMODITIES (FULL REPORTS OF INVESTIGATIONS MADE WITH RESPECT TO THE SAFETY OF THE PESTICIDE CHEMICAL 2(245-TRICHL0R0PHEN0XY) PROPIONIC ACID (SA50.00.01.P1)(PP8F0675). ACUTE POISONING FROM WEED KILLER 2AD (FOLIA MEDICA A4, 480-A85). UNIV DI PAVITA FOLIA MEDICA FOLLOW UP INFORMATION ON STUDY OF CHLORACNE BY DR KLIGMAN CTTL. RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON FORRON BRUSH KILLER(M-1368) (T2.30-123-1). BARRONS KC GAY HH HART A KILIAN DJ MCINTYRE HH VANVALKENBURG W BOUNDY RH GRAY HE HYMAS TA LUCE EN PERKINS RP WRIGHT N RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON INVERTON (BRUSH KILLER). T2.30-101-1. OLSON KJ BESHGETOOR AW ELSHERE D HART A KILIAN DJ MUSSELL DR WRIGHT N BOUNDY RH GAY HH HYMAS TA LUCE EN PERKINS RP TOXICITY OF DOW BRUSH KILLER 50-50 (T2.30-28-1). ROWE VK WOLF MA ferfl(>,, NUMBER DATE DOCUMENT 2368 10/29/53 AUTHORS ADDRESSEE COPYEE ADAMS EM OYEN F DON BARRONS ICC DAVIDSON JH KAGY JF PRESCOTT RF DOCUMENT 2369 AUTHOR: DOW ADDRESSEE: COPYEE: 04/12/56 DOCUMENT 2370 04/15/69 AUTHOR: BEAUCHAMP RR ADDRESSEE COPYEEs BEAUCHAMP RR BLAIR EH GORDON HL KILIAN DJ MCCOLLISTER DD SCHWARZ AJ DOCUMENT 2371 AUTHOR DOW ADDRESSEE COPYEE 04/17/69 DOCUMENT 2372 01/26/60 AUTHOR HOYLE HR ADDRESSEE COPYEE: DOCUMENT 2373 02/23/60 AUTHOR: ADDRESSEE COPYEE: CO CO CO DOW DOW ELSHERE D HART A KILIAN DJ PERKINS RP WRIGHT N TYPE REPORT DOW PAGES 7 ALLEN WW BESHGETOOR AW DUTTON WC LUCE EN SUNDERLAND WW TECH 2 REPORT DOW DOW BURGERT BE HOLDER BB KIMMEL CE MCINTYRE HH WRIGHT N 2 REPORT NORRIS JM 6 REPORT OYEN F 2 REPORT OLSON KJ BARRONS KC GAY HH HYMAS TA LUCE EN SCOLES GW 19 TITLE PAGE 339 RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON DOW BRUSH KILLER 50-50. ESLUNN E MAXEY JS ALLINSON RL BOUNDY RH GAY HH LYNN GE WHITE LC ALQUIST FN BRITTON EC GREENE LM MACCUTCHEON SM WRIGHT P ESTERON BRUSH KILLER OS M-726 (T2.30-71-1) . M-3401 BRUSH KILLER A TORDON ACID FORMULATION (BC T2.MO-3401-2). NORRIS JM TORKELSON TR AXE FD EDWARDS H JOHNSON JE LLOYD BH MORSE D BARRON J ELSHERE D KAGY JF MACCUTCHEAN SM ROBINSON VB TOXICOLOGICAL PROPERTIES OF M-3A01 BRUSH KILLER-A TORDON ACID FORMULATION. M-168A ESTERON BRUSH KILLER TYPE (DATA SHEET OF PROPERTIES, HEALTH HAZARDS, AND PRECAUTIONS FOR SAFE HANDLING OF MATERIALS). OLSON KJ DOW RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON AGRICULTURAL CHEMICAL FORMULATION M-1684 (ESTERON BRUSH KILLER TYPE). OYEN F BOUNDY RH GREENE LM JONES GD LYNN GE STENGER VA COLBY RW HAMMER OH KAGY JF MCINTYRE HH TISDALE WL NUMBER DOCUMENT 237A DATE 05/06/59 TYPE REPORT PAGES 26 AUTHOR: DOW ADDRESSEE* COPYEE* DOW ELSHERE D HAMMER OH KAGY JF MCINTYRE HH VANVALKENBURG JW MCCOLLISTER DD BARRONS KC GAY HH HART A KILIAN DJ PERKINS RP WRIGHT N DOCUMENT 2375 07/02/56 AUTHOR* DOW ADDRESSEE* COPYEE* DOW BESHGETOOR AW ELSHERE D KAGY JF LYNN GE REPORT 21 MCCOLLISTER DD ALLINSON RL BOUNDY RH GAY HH KELLY JA MACCUTCHEON SM DOCUMENT 2376 10/30/53 AUTHOR* ADAMS EM ADDRESSEE* COPYEE* ALLEN WW BESHGETOOR AW DOW KAGY JF PRESCOTT RF REPORT OYEN F 28 ALLINSON RL BOUNDY RH DUTTON WC LUCE EN SUNDERLAND WW DOCUMENT 2377 AUTHOR* ADDRESSEE COPYEE* 00/00/78 DOCUMENT 2378 11/22/57 AUTHOR* DOW ADDRESSEE* COPYEE* DOW BOUNDY RH GAY HH JONES G D MCINTYRE HH WHITE LG REPORT 17 REPORT 23 MCCOLLISTER DD ALLINSON RL COLBY RW GREENE LM KILIAN DJ MUSSELL DR WRIGHT N CO a? TITLE PAGE 340 RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON M-1447 AND M-1A43 WEED KILLER FORMULATIONS (SIMILAR TO ESTERON 2A5 OS AND ESTERON BRUSH KILLER OS RESPECTIVELY). WOLF MA BOUNDY RH GRAY HE HYMAS TA LUCE EN STENGER VA COLBY RW GREENE LM JONES GD LYNN GE TISDALE WL RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON ESTERON BRUSH KILLER O.S. (M-726). OLSON KJ ALQUIST FN BRITTON EC GREENE LM KILIAN DJ SUNDERLAND WW BARRONS KC COLBY RW HART A LUCE EN WRIGHT N RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON DOW BRUSH KILLER T. ALQUIST FN BRITTON EC GAY HH LYNN GE WHITE L BARRONS KC DAVIDSON JH GREENE LM MACCUTCHEON SM WRIGHT P AN EVALUATION OF 24D DATA. RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON BRUSH KILLER X, WEED KILLER X, AND BRUSH KILLER TX. OLSON KJ ATHAY RM DOSSER RC HART A LUCE EN PERKINS RP BESHGETOOR AW ELSHERE D HYMAS TA MARTIN D TISDALE WL  -ilBER DOCUMENT 2379 AUTHOR: DOW ADDRESSEE COPYEE: DATE 01/22/59 DOCUMENT 2380 12/27/61 AUTHOR DOW ADDRESSEE: COPYEE HOYLE HR DOCUMENT 2381 07/06/79 AUTHOR ADDRESSEE COPYEE: BOHL RW DOW HEINZE BA MELCHER RG RAMPY DOCUMENT 2382 12/30/81 AUTHOR: DOW LANHAM JM ADDRESSEE COPYEE: DOCUMENT 2383 11/29/53 AUTHOR: DOW ADDRESSEE COPYEE ADAMS EM BARRONS KC DAVIDSON JH KAGY JF PRESCOTT RF DOCUMENT 2384 01/10/78 TYPE PAGES TECH 2 HOYLE HR TECH i OLSON KJ OYEN F 2 REPORT 38 DAVEY KF BRADLEY TD KMETKO MOREHOUSE DS RAPP MEDREC KEELER P 3 REPORT OYEN F 7 ALLEN WW BESHGETOOR AW DUTTON WC LUCE EN SUNDERLAND WW REPORT 7 AUTHOR: ARSTILA AU ADDRESSEE1 COPYEE * SORVARI TE CO CO or Tl 'AGE 341 FORRON BRUSH KILLER (DATA SHEET OF PROPERTIES HEALTH HAZARDS AND PRECAUTIONS FOR SAFE HANDLING OF MATERIALS). MCCOLLISTER DD WOLF MA SILVEX ACID M-2121. DATA SHEET OF PROPERTIES, HEALTH HAZARDS, AND PRECAUTIONS FOR SAFE HANDLING OF MATERIALS. 1 COMPREHENSIVE SURVEY OF EMPLOYEES EXPOSURES TO AIRBORNE CONTAMINANTS IN THE MI DIV 24D PLANT, 489 BUILDING, 771000 TO 790300 CHEH23.14-11-2(8)). DOW BUZZELLI DT KOLESAR RC OLSON RD SCHNEIDER EJ DERSNAH BE LANGNER RR OWEN PW SILVERSTEIN MEDICAL INFORMATION ON ESTERON 245 CTTL. FISHBECK WA SCHARNWEBER HC RESULTS OF RANGE FINDING TOXICOLOGICAL TESTS ON DOW BRUSH KILLER T ALLINSON RL BOUNDY RH GAY HH LYNN GE WHITE L ALQUIST FN BRITTON EC GREENE LN MACCUTCHEON SM WRIGHT P AN EPIDEMIOLGICAL FEASIBILITY STUDY ON THE EFFECTS OF TCDD ON FINNISH FORESTRY, ROAD AND RAILWAY WORKERS (PRELIMINARY FINDINGS)(IARC MTG ON DIBENZODIOXINS AND DIBENZOFURANS, 780110 TO 780111, LYON, FRANCE). UNIV OF JYVASKYL FIN NUMBER DATE TYPE DOCUMENT 2385 OO/OO/OO NEWS AUTHOR: CANADIAN UNION OF PUBLIC ADDRESSEE COPYEEs PAGES 1 DOCUMENT 2386 10/27/80 AUTHOR! CBC RADIO ADDRESSEE! COPYEE NEWS SAFE S 2 DOCUMENT 2387 10/24/80 MEMO 1 AUTHOR CANADIAN AG CHEM ASSN CHEVALIER J ADDRESSEE! CANADIAN AG CHEM ASSN BD DF DIRECTORS COPYEEs DOCUMENT 2388 AUTHOR DOW ADDRESSEE COPYEEs 1 00/00/00 DOCUMENT 2389 10/24/80 AUTHOR* DEPT OF AG CAN ADDRESSEE COPYEEs NEWS NEWS ORMROD W 1 2 DOCUMENT 2390 10/12/73 AUTHOR: DOW ADDRESSEE EPA COPYEE HEIN ND STRINGER WM LETTER MULLISON WR MOUNTFORT RF LENG ML WATSON AJ 1 DOCUMENT 2391 AUTHOR DOW ADDRESSEE COPYEE: 00/00/00 LABEL 2 DOCUMENT 2392 AUTHOR: ADDRESSEE COPYEE 07/11/66 LABEL 1 DOCUMENT 2393 10/30/80 AUTHOR: STEPHENS R ADDRESSEE: COPYEE: NEWS 1 GLOBE AND MAIL Vhb-(L 4336 TITLE PAGE 342 BEWARE OF THE WEED KILLER Z45T AND 245TP (HEALTH & SAFETY ALERT 3). DIOXIN LEVELS IN 24D AND 245T (CBC 'RADIO NOON'). UNIV OF GUELPH 24D ISSUE. MEMBERSHIP PROVINCIAL CNCL EXECUTIV 24D TESTS. KURON BRUSH KILLER EPA REG <464-162 YOUR LETTER OF 730813. MCCOLLISTER DD SOUTHWICK L KURON BRUSH KILLER. KURON PROPOSED REVISIONS. EMPLOYERS WITHHOLD TRUTH ABOUT TOXICS, MD WARNS WORKERS (THE GLOBE AND MAIL MAIL). NUMBER DOCUMENT 2394 DATE 12/00/79 TYPE ABSTRACT PAGES 1 AUTHOR ELO HA ADDRESSEE COPYEE DOCUMENT 2395 00/00/77 PRINT YLITALO P ABSTRACT 1 AUTHOR ELO H ADDRESSEE COPYEE DOCUMENT 2396 12/00/77 PRINT YLITALO P ABSTRACT 1 AUTHOR AHMED FE ADDRESSEE COPYEE DOCUMENT 2397 12/00/77 PRINT LEWIS NJ ABSTRACT 1 AUTHOR YOUNG JF ADDRESSEE COPYEE DOCUMENT 2398 00/00/77 PRINT HALEY TJ ABSTRACT AUTHOR PARK J ADDRESSEE COPYEE $ ,Vv3 U> CO CO Vi PRINT DARRIEN I TITLE PAGE 343 DISTRIBUTION OF 2-METHYL-4-CHLOROPHENOXYACETIC ACID AND 24D IN MALE RATS EVIDENCE FOR THE INVOLVEMENT OF THE CENTRAL NERVOUS SYSTEM IN THEIR TOXICITY CTOX APPL PHARMACOL 51(3), 439-446)(THIS IS AN OFFLINE BIBLIOGRAPHIC CITATION LIST GENERATED BY MEDLARS 2 N.L.M.'S NATL INTERACTIVE RETRIEVAL SERVICE). TOX APPL PHARMACOL SUBSTANTIAL INCREASE IN THE LEVELS OF CHLOROPHENOXYACETIC ACIDS IN THE CNS OF RATS AS A RESULT OF SEVERE INTOXICATION (ACTA PHARMACOL TOX (KBH) 41(3), 280-284KTHIS IS AN OFFLINE CITATION LIST GENERATED BY MEDLARS 2 N.L.M.'S NATL INTERACTIVE RETRIEVAL SERVICE) ACTA PHARMACOL TOX PESTICIDE INDUCED OUABAIN RESISTANT MUTANTS IN CHINESE HAMSTER V79 CELLS (CHEM BIO INTERACT 19(3), 369-374KTHIS IS AN OFFLINE BIBLIOGRAPHIC CITATION LIST GENERATED BY MEDLARS 2 N.L.M.'S NATL INTERACTIVE RETRIEVAL SERVICE). HART RW CHEM BIO INTERACT PHARMACOKINETIC STUDY OF A PATIENT INTOXICATED WITH 24D AND 2-METH0XY-36-DICHL0R0BENZ0IC ACID (CLIN TOX 11(5), 489-500MTHIS IS AN OFFLINE BIBLIOGRAPHIC CITATION LIST GENERATED BY MEDLARS 2 N.L.M.'S NATL INTERACTIVE RETRIEVAL SERVICE). CLIN TOX PHARMACOKINETIC STUDIES IN SEVERE INTOXICATION WITH 24D AND MECOPROP (CLINICAL TOXICOLOGY AMSTERDAM, EXCERPTA MEDICA, 154-155) (W3 EX89 417 1976KTHIS IS AN OFFLINE BIBLIOGRAPHIC CITATION LIST GENERATED BY MEDLARS 2 N.L.M.'S NATL INTERACTIVE RETRIEVAL SERVICE) PRESCOTT LF EXCERPTA MEDICA NUMBER DOCUMENT 2399 DATE 12/00/76 TYPE ABSTRACT PAGES 1 PRINT AUTHOR CENCI P CAVAZZINI G NUOVI ANN IG MICROBIO ADDRESSEE COPYEEs S TITLE PAGE 344 EFFECTS OF 24D (SODIUM SALT) ON REPRODUCTIVE PROCESSES IN MICE (NUOVI ANN IG MICROBIO 27(6), 569-584KTHIS IS AN OFFLINE BIBLIOGRAPHIC CITATION LIST GENERATED BY MEDLARS 2 N.L.M.'S NATL INTERACTIVE RETRIEVAL SERVICES). CORRADINI L MARCATI F DOCUMENT 2400 00/00/74 AUTHOR: ELINA VA ADDRESSEES COPYEEi ABSTRACT 1 EFFECT OF PRODUCTS OF ORGANOCHLORINE HERBICIDE OF PRODUCTION ON SPECIFIC FUNCTIONS OF THE FEMALE BODY (GIG TR SOSTOYANIA SPETSIFICHESKIKH FUNKTS RAB NEFTEKHIM KHIM PROM STI 187-190). UFIM INST GIG PROFZABOL DOCUMENT 2401 01/00/80 AUTHOR HOFFMANN LAROCHE ADDRESSEE! COPYEEs NEWS REPORT REGGIANI G 20 ACUTE HUMAN EXPOSURE TO TCDD IN SEVESO, ITALY (JOUR OF TOX AND ENVIRON HEALTH 6(1), 27-43). DOCUMENT 2402 02/10/62 NEWS AUTHORS ADDRESSEE COPYEEs DESI I MED UNIV BUDAPEST REPORT SOS HUNGAR J 8 NEW EVIDENCE CONCERNING THE NERVOUS SITE OF ACTION OF A CHEMICAL HERBICIDE CAUSING PROFESSIONAL INTOXICATION (ACTA PHYSIOLOGIA 22, 73-80). NIKOLITS I INST OF PATHOPHYSIOLOGY DOCUMENT 2403 09/12/68 AUTHOR! LENG ML ADDRESSEE COPYEEs REPORT DOW 27 PETITIONS FOR THE ESTABLISHMENT OF TOLERANCES ON RAW AGRICULTURAL COMMODITIES FOR THE PESTICIDE CHEMICALS (SUPPLEMENTKSECTION C; METABOLISM). DOCUMENT 2404 00/00/73 AUTHOR! BRADY TP LANGER HG ADDRESSEE COPYEEs REPORT BRIGGS PR SHANNON TW 7 THERMAL CHEMISTRY OF CHLORINATED PHENOLS CHLORODIOXINS ORIGIN AND FATE (ADVANCES IN CHEMISTRY SERIES (120), 26-32). DALTON LA DOW b b b '( , 4338 ---I AU IHR I KEARNEY PC ADDRESSEt* COPYEE: 0 ' .' ..f DOCUMENT 2406 09/18/80 LEGIS 3 AUTHOR* BREINHOLT MM ADDRESSEE* DOW COPYEE JACKSON TG SUPPLEMENTAL SUBMISSION OF PHILIP C. KEARNEYS APPENDIX I ON BEHALF OF THE SECRETARY OF AGRICULTURE FOR THE U.S. CDOW, ET AL., PETITIONERS)(DOCKET NO. 415, ET A L .)(EPA BEFORE THE ADMINISTRATOR)(PHILIP KEARNEY EXHIBITS). USDA HENKER JA DOCUMENT 2407 00/00/00 AUTHOR* LYMAN FL ADDRESSEE* LAFOLLETTE JOHN COPYEE* QUES 14 LAFOLLETTE JOHNSON SYMPTON SILVEX TCDD. DOCUMENT 2408 00/00/00 AUTHOR* LYMAN FL ADDRESSEE* COPYEE* REPORT 1 COMMENTS ON SILVEX AND TCDD SYMPTOMS. DOCUMENT 2409 07/13/83 AUTHOR* STEVENS KM ADDRESSEE* COPYEE* MEMO 11 REPORT STATE UNIV OF NY AGENT ORANGE TOXICITYj A QUANTITATIVE PERSPECTIVE (HUMAN TOX 1, 31-39). DOCUMENT 2410 11/26/77 REPORT 18 EMBRYO PROBLEMS POSED BY THE SEVESO ACCIDENT. AUTHOR* FISHER P LAB OF EMBRYOLOGY PARI TUCHMANNDUPLESSIS H ADDRESSEE* LECONCOURS MEDICAL, PARI COPYEE* DOCUMENT 2411 12/21/71 AUTHOR* DOW ADDRESSEE* DOW ROWE VK COPYEE* REPORT 11 MCCOLLISTER DD GEHRING PJ FDA TERATOLOGY STUDIES ON 245T AND SILVEX. LYNN GE ROBINSON VB CO CO CO NUMBER DOCUMENT 2412 DATE 12/13/76 AUTHOR: BLAU GE SAUERHOFF MW ADDRESSEE COPYEE! DOCUMENT 2413 AUTHOR: DOW ADDRESSEE COPYEE 00/00/79 DOCUMENT 2414 AUTHOR ERNE K ADDRESSEE COPYEE: 04/00/73 DOCUMENT 2415 00/00/00 TYPE REPORT PAGES 26 BRAUN WH REPORT 18 REPORT 10 NORDKVIST M REPORT 8 AUTHOR: PALMER JS ADDRESSEE COPYEE DOCUMENT 2416 12/00/80 AUTHOR BIBRA BULLETIN ADDRESSEE COPYEE DOCUMENT 2417 07/28/78 AUTHOR DOW ADDRESSEE: COPYEE: DOW GARFIELD EL DOCUMENT 2418 AUTHOR: DOW ADDRESSEE! COPYEE: 03/21/78 -i -C. ^ CO CO 6s o RADELEFF RD NEWS LAKE BG 3 REPORT GANTZ RL BRAUN WH LENG ML REPORT HOLDER BB 10 17 TITLE PAGE 346 THE FATE OF SILVEX FOLLOWING ORAL ADMINISTRATION TO HUMANS (JOUR OF TOX & ENVIRON HEALTH)(PRESENTED ANNUAL MEETING SOCIETY OF TOX, TORANTO, 770300M770164). DOW GORDON HL AN EVALUATION OF 2AD. TOXICITY STUDIES WITH PHENOXY HERBICIDES ON REINDEER (HORMOSLYR RESEARCH WITH REINDEER). THE TOXICOLOGIC EFFECTS OF CERTAIN FUNGICIDES AND HERBICIDES ON SHEEP AND CATTLE (ANNALS NY ACADEMY OF SCIENCES, 729-736)(PETITION FOR THE ESTABLISHMENT OF TOLERANCES FOR THE PESTICIDE CHEMICAL, 245T ON RAW AGRICULTURAL COMMODITIES, SECTION C, FULL REPORTS OF INVESTIGATIONS MADE WITH RESPECT TO THE SAFETY OF THE PESTICIDE CHEMICAL, 2A5T). USDA DIOXIN, INDUCTION OF XENOBIOTIC METABOLISM 2(BIBRA BULLETIN, 503-505). DETERMINATION OF PHENOXY HERBICIDES IN URINE AND BLOOD SAMPLES FROM 2A5T PLANT PERSONNEL TWO (ANALYTICAL REPORT, AL 78-50668). LANGHORST ML CHENOWETH MB MCCARTY LP CRUMMETT WB SAUNDERS JH A LONGEVITY SURVEY OF EMPLOYEES EXPOSED TO 245T. OLSON RD OTT MG NUMBER DATE DOCUMENT 2419 12/19/78 AUTHOR ADDRESSEE COPYEE DAVIDSON JH JOHNSON R WARREN LE TYPE REPORT PAGES 21 DOM KOCIBA RJ DOCUMENT 2420 11/00/80 NEWS 21 AUTHOR HUFF JE SARACCI R ADDRESSEE COPYEE REPORT INTL AGENCY FOR RES TOMATIS L DOCUMENT 2421 AUTHOR DOW ADDRESSEE COPYEE 01/00/80 NEWS HOLDER BB 4 DOCUMENT 2422 01/28/80 AUTHOR NATL FARMERS UNION ADDRESSEE COSTLE D COPYEE REPORT EPA 3 DOCUMENT 2423 AUTHOR DOW ADDRESSEE COPYEE 01/00/80 REPORT HOLDER BB 4 DOCUMENT 2424 AUTHOR FOE ADDRESSEE EPA ,, COPYEE 08/28/78 LETTER JELLENICK S 1 DOCUMENT 2425 AUTHOR OU LT ADDRESSEE COPYEE 12/00/76 REPORT SIKKA HC 5 CO V TITLE PAGE 347 ASSESSMENT OF HAZARDS ASSOCIATED WITH THE USE OF 245T, 24D AND SILVEX IN REFORESTATION PRACTICES. HOLDER B MORGAN A HOLDER BB SCHWETZ B LONG-TERM HAZARDS OF POLYCHLORINATED DIBENZODIOXINS AND POLYCHLORINATED DIBENZOFURANS (ENVIRON HEALTH PERSPECTIVES 36, 221-240). ON C MOORE JA NATL TOX PROGRAM A MORTALITY ANALYSIS OF EMPLOYEES ENGAGED IN THE MANUFACTURE OF 245T (REPRINTED FROM JOURNAL OF OCCUPATIONAL MEDICINE 22(1), 47-50) OLSON RD OTT MG RESOLUTION ON CONSOLIDATED HEARINGS ON CANCELLATION OF THE EPA REGISTRATION OF 245T AND SILVEX HERBICIDES (FIFRA DOCKET 415 ET A L ) A MORTALITY ANALYSIS OF EMPLOYEES ENGAGED IN THE MANUFACTURE OF 245T (JOUR OF OCCUPATIONAL MEDICINE 22(1), 47-50). OLSON RD OTT MG EPA SHOULD TAKE PUBLIC HEALTH ACTION CTTL. EXTENSIVE DEGRADATION OF SILVEX BY SYNERGISTIC ACTION OF AQUATIC MICROORGANISMS. SYRACUSE UNIV RES CORP N &hh'(Z NUMBER DOCUMENT 2426 AUTHOR: ADDRESSEE COPYEE DATE 04/21/72 DOCUMENT 2427 AUTHOR' DOW ADDRESSEE EPA COPYEE DOW 11/09/77 DOCUMENT 2428 AUTHOR! ADDRESSEE COPYEE: 09/26/78 DOCUMENT 2429 10/25/71 AUTHOR DOW ADDRESSEE COPYEE DOW EDWARDS; H GORING CA KILIAN DJ MCINTYRE SHAVER RJ DOCUMENT 2430 AUTHOR DOW ADDRESSEE COPYEE! DOW 03/01/71 DOCUMENT 2431 03/19/75 AUTHOR DOW ADDRESSEE COPYEE: DOW CARL ETON RE HORVATH B KOCIBA RJ MOOLENAAR RAMPY LW DOCUMENT 2432 05/11/80 AUTHOR: BRINEY WF ADDRESSEE' COPYEE: CO ro TYPE NEWS REPORT PAGES 1 LETTER 1 MULL ISON WR MOUNTFORT RF COOK COL REPORT 65 ABSTRACT NORRIS JM 1 AXE FD FREVEL LK HOLDER BB KIMMEL CE PITCHFORTH L SILVERSTE1N L AUTH 1 GEHRING PJ REPORT KEELER PA VACCARO J FREVEL LK HUMISTON C LEAVITT FC OLSON RD RINZEMA L 1 NEWS 1 TITLE DOW REDEFINES WORD IT DOESN'T LIKE (SCIENCE 176, 262) PAGE 3A8 IR4 PETITION 4E1476 REGARDING THE USE OF SILVEX ON CITRUS. LENG ML MARKLE GM REPORT OF THE CONSULTATIVE COUNCIL ON CONGENITAL ABNORMALITIES IN THE YARRAM DISTRICT. EYE IRRITATION STUDY ON TCDD (CHEM BIO RES). BLAIR EH GEHRING PJ HORVATH B MACCUTCHEON SM ROBINSON VB BURGERT BE GORDON HL JOHNSON JE MCCOLLISTER DD SCHWARZ AJ TCDD (REQUEST FOR PRELIMINARY TOX STUDIES). I VK NORRIS JM WIPE SAMPLES FROM 1803 BUILDING TCDD FEEDING STUDY (TOX PROPERTIES AND IND HANDLING HAZARDS OF). OLSON KJ VACCARO J BLAIR EH GORDON HL KILIAN DJ MACCUTCHEON SM PRUITT ME ROBINSON VB BURGERT BE HOLDER BB KIMMEL CE MCCOLLISTER DD PULLIN T SHAVER RJ DONT SPRAY POISON (PRESCOTT COURIER 800511). NUMBER DATE DOCUMENT 2433 05/01/80 AUTHOR HAMMOND VINDICATOR ADDRESSEE COPYEE TYPE PAGES NEWS MCMAHON BT 1 DOCUMENT 2434 07/10/80 REPORT AUTHOR FRIENDS OF THE EARTH ADDRESSEE COPYEE JANSSON E 6 DOCUMENT 2435 00/00/00 ABSTRACT AUTHOR GAINES TB HIGHMAN B UNIV OF AR COL OF MEDICI ADDRESSEE COPYEE 1 DOCUMENT 2436 00/00/78 NEWS 12 REPORT AUTHOR ENGEL HWB JANSEN LMV NATL INST OF PUBLIC HEAL VOS JG ADDRESSEE COPYEE DOCUMENT 2437 09/01/80 AUTHOR GRAPEVINE ADDRESSEE COPYEE NEWS WRIGHT T 2 DOCUMENT 2438 00/00/77 REPORT AUTHOR DEPT OF ONCOLOGY UMEA ADDRESSEE COPYEE HARDELL L 7 DOCUMENT 2439 AUTHOR DOW ADDRESSEE COPYEE 04/27/78 REPORT GLAS RD 15 v CO CO TITLE POISON HITS PARISH (HAMMOND VINDICATOR). PAGE 349 PETITION AGAINST THE USE OF 24D BECAUSE OF IS TOXIC NATURE AND HAZARD TO PUBLIC HEALTH CTTL. RENAL ALKALINE PHOSPHATASE ACTIVITY IN FETAL OFFSPRING OF MATERNAL MICE GIVEN 245T (ABSTRACTS FIFTEENTH ANNUAL MEETING, 145). NATL CENTER FOR TOX RES SCHUMACHER HJ STUDIES ON TCDD INDUCED IMMUNE SUPPRESSION AND DECREASED RESISTANCE TO INFECTION, ENDOTOXIN HYPERSENSITIVITY, SERUM ZINC CONCENTRATIONS AND EFFECT OF THYMOSIN TREATMENT (TOX 9, 75-86). KREEFTENBERG JG MINDERHOUD A CONFESSIONS OF AN EXLAWN SPRAYER (GRAPEVINE, 50). MALIGNANT MESENCHYMAL TUMORS AND EXPOSURE TO PHENOXY ACIDS A CLINICAL OBSERVATION (LAKARTIDNINGEN 74(33), 2753-2754). DETERMINATION OF RESIDUES OF MCPA TRICLOPYR 24D, 245T AND SILVEX IN BLOOD AND URINE BY ELECTRON CAPTURE GAS CHROMATOGRAPHY. NUMBER DATE DOCUMENT 2440 09/00/76 AUTHOR: HONOROF I ADDRESSEE* COPYEE: TYPE NEWS PAGES 4 DOCUMENT 2441 00/00/78 REPORT 13 AUTHOR* BOSSHARDT HP SWISS FED RES STATION ADDRESSEE* COPYEE* BUSER HR UNIV OF UMEA DOCUMENT 2442 AUTHOR* NFPA ADDRESSEE* COPYEE: 08/14/80 NEWS 4 DOCUMENT 2443 00/00/78 REPORT 28 AUTHOR* AG ENVIRON QUALITY INST BEALL ML JR ADDRESSEE* COPYEE* DOCUMENT 2444 00/00/78 AUTHOR* ISENSEE AR ADDRESSEE COPYEE* ABSTRACT USDA 1 DOCUMENT 2445 08/24/74 AUTHOR DONNELL HD ADDRESSEE COPYEE* REPORT 1 MO DEPT HEALTH AND DOCUMENT 2446 02/07/77 REPORT 8 AUTHOR RAMEL C ADDRESSEE COPYEE* CO TITLE PAGE THE MOMENTUM OF IGNORANCE (REPORT TO THE CONSUMER 6(134). 350 FORMATION OF POLYCHLORINATED DIBENZO-P-DIOXINS (PCDDS) AND DIBENZOFURANS (PCDFS) BY BURNING OR HEATING CHLOROPHENATES (CHEMOSPHERE 2, 269-281)(PESTICIDES ABSTRACTS 3, 269-281). MARKLUND S RAPPE C FOREST CHEMICALS NEWS 2(6). FINAL REPORT ON TCDD APPLIED WITH SILVEX TO TURF IN MICROAGROECOSYSTEMS (AN INTERAGENCY AGREEMENT BETWEEN THE EPA AND THE USDA). NASH RG BIOACCUMULATION OF TCDD (ECOL BULLETIN 27, 255). ILLNESS ASSOCIATED WITH TCDD CONTAMINATED SOIL MO (COMMUNICABLE DISEASE CENTER MORBIDITY AND MORTALITY WEEKLY REPORT). WELFA CHLORINATED PHENOXY ACIDS AND THEIR DIOXINS. MODE OF ACTION HEALTH RISKS AND ENVIRONMENTAL EFFECTS (ECOLOGICAL BULLETINS 27)(SHEDISH NATURAL SCIENCE RESEARCH COUNCIL). NUMBER DOCUMENT 2454 DATE 00/00/70 AUTHOR COURTNEY KD ADDRESSEE COPYEE DOCUMENT 2455 00/00/77 AUTHOR KEARNEY PC UNIV OF MD ADDRESSEE COPYEE DOCUMENT 2456 01/10/78 AUTHOR MOORE JA ADDRESSEE COPYEE DOCUMENT 2457 00/00/74 AUTHOR BOHME C RALPH MCELROY CO ADDRESSEE COPYEE DOW DOCUMENT 2458 12/00/74 AUTHOR DOW ADDRESSEE COPYEE DOCUMENT 2459 08/17/79 AUTHOR GUNBY P ADDRESSEE COPYEE DOCUMENT 2460 06/12/79 AUTHOR REUBER MD ADDRESSEE COPYEE TYPE ABSTRACT CHART EPA PAGES 8 REPORT MENZER RE USDA 5 REPORT 8 REPORT 23 FED HEALTH OFF WGERM GEHRING PJ REPORT 2 LENG ML NEWS JAMA 4 REPORT 24 I h h h ( 00 or TITLE PAGE PRENATAL EFFECTS OF HERBICIDES, EVALUATION BY THE PRENATAL DEVELOPMENT INDEX (ENVIRON CONTAMINATION 8 TOX 5(A). 352 TCDD IN VITRO BINDING TO RAT LIVER MICROSOMES(BULLETIN OF ENVIRON CONTAMINATION & TOX 18(1), 9-13). NELSON JO PLIMMER JR COMPARATIVE TOXICITY OF DIBENZODIOXINS AND DIBENZOFURANS (IARC MEETING ON DIBENZODIOXINS AND DIBENZOFURANS 780110 TO 780111 LYON, FRANCE). THE METABOLISM OF 2A5T AND 24D IN RATS AND MICE(ARCHIVES OF TOX 32, 217-225) (WGERM). GRUNOW W MCELROY R AMENDMENT TO PP 8F0675 REQUESTING TOLERANCES FOR SILVEX 2-245-TRICHL0R0PHEN0XY) PROPIONIC ACID IN FOOD AND FORAGE CROPS MEAT AND MILK. PLENTY OF FUEL FOR AGENT ORANGE DISPUTE MEDICAL NEWS (JAMA 242(7), 593-597). CARCINOGENICITY OF 24D. NUMBER DATE DOCUMENT 2467 03/01/78 AUTHOR DOW ADDRESSEE COPYEE BEACHELL J DISHBURGER HJ GRAY JA JANTZ OK MCCOLLISTER DD SHADOFF LA WARD WH TYPE PAGES REPORT 4 LENG ML BLAIR EH DONALDS JE HANSEN JC JENSEN DJ MOSS RD SMITH LL WARREN LE TITLE PAGE 354 SYMPOSIUM ON USE OF HERBICIDES IN FORESTRY (24D, 245T, SILVEX, TCDDMUSDA/EPA/CITIZENS GROUPS). CRUMMETT WB GEHRING PJ HEFNER RE KARWAL JH MULL ISON WR STEARNS WJ WESSEL MR DAVIDSON JH GETZENDANER ME HOERGER FD KOCIBA RJ SEWARD WB TRAYNOR MJ DOCUMENT 2468 09/21/76 REPORT 24 COMPARATIVE METABOLISM OF PHENOXY HERBICIDES IN ANIMALS. AUTHOR DOW LENG ML ADDRESSEE COPYEE DOCUMENT 2469 00/00/70 AUTHOR BELYAVSKAYA L RAMAN SK ADDRESSEE COPYEE ABSTRACT 1 CHEM ABSTRACTS TOXIC EFFECT OF SOME HERBICIDES ON FISH AND AQUATIC INVERTEBRATES (VIDOVOI SOSTAV EKOL PROD GIDROBIONTOV VOLGOGRAD VODOKHRAN 690000, 93-98KCHEM ABSTRACTS 72, 240). KONSTANTINOV AS KONSTANTINOVA NS DOCUMENT 2470 00/00/77 AUTHOR BERRY DL NAMKUNG MJ WILSON NM ADDRESSEE COPYEE REPORT 6 BRACKEN WM OAK RIDGE NATL LAB ZACHARIAH PK TRANSPLACENTAL INDUCTION OF MIXED FUNCTION OXYGENASES IN EXTRA HEPATIC TISSUES BY TCDD (BIOCHEMICAL PHARMACOLOGY 26, 1383-1388) EAST TN RES CENTER JUCHAU MR SLAGA TJ UNIV WA DOCUMENT 2471 06/16/80 REPORT 45 24D. AUTHOR DEPT OF HEALTH SERVICES DEPT OF IND RELATIONS ADDRESSEE COPYEE EVALUATION OF THE HUMAN HEALTH HAZARDS. DOCUMENT 2472 AUTHOR DOW ADDRESSEE COPYEE 11/09/70 REPORT DUNN FL 9 STUDY OF THE TERATOGENICITY OF TCDD IN THE R A K F D COSMET TOX 9, 405-412). ROWE VK SPARSCHU GL T h hh-(T, CO cn NUMBER DATE TYPE DOCUMENT 2473 06/25/80 LETTER AUTHOR DEPT OF HEALTH SERVICES/ LAPPE M ADDRESSEE* LOS ANGELES TIMES COPYEE* PAGES 1 DOCUMENT 2474 00/00/78 AUTHOR* HUFF JE PISA UNIV ADDRESSEE* COPYEE* REPORT 44 INTL AGENCY FOR RES MASSON JS DOCUMENT 2475 00/00/00 AUTHOR* DOM WALKER RE ADDRESSEE* COPYEE* REPORT HOLMES RD 3 DOCUMENT 2476 09/22/67 MEMO 1 AUTHOR* DOW ADDRESSEE* COPYEE* HERITIER WJ DOCUMENT 2477 11/08/67 AUTHOR* COLLINS B ADDRESSEE* DOM COPYEE* LETTER DOM ARGYLE B 1 DOCUMENT 2478 AUTHOR* DOM ADDRESSEE* DOM COPYEE* 10/26/67 LETTER HOLDER BB HERITIER WJ 1 DOCUMENT 2479 AUTHOR* DOM ADDRESSEE* COPYEE* 12/27/67 MINUTES 5 HERITIER WH DOCUMENT 2480 AUTHOR* DOM ADDRESSEE* COPYEE* 09/22/67 MINUTES 1 HERITIER WJ Bbhh'^T CO <1 TITLE PAGE 355 WOULD LIKE TO CORRECT ERRONEOUS IMPRESSION ABOUT 2AD LEFT LOS ANGELES TIMES ARTICLE CTTL. A REVIEW OF THE GENETIC TOXICOLOGY OF CHLORINATED DIBENZO-P-DIOXINS. ON C LOPRIENO N OAK RIDGE NATL LAB CHLORACNE PROBLEM IN 199 BUILDING. LUECK AF SILVERSTEIN LG ALL FINISH PRODUCT LINES OR EQUIPMENT CAN BE SALVAGED WHEN DEMOLISHING 199 BLDG BUT ANY LINES OR EQUIPMENT THAT HANDLED CRUDE PRODUCT OR PHENATE OIL MUST BE BURIED CTTL. REMOVAL OF TRICHLOROPHENOL EQUIPMENT 199 BUILDING. CHLORACNE 199 BUILDING DEMOLITION. REMOVAL OF TRICHLOROPHENOL PROCESS EQUIPMENT AT 199 BUILDING. MEETING 199 BUILDING FRIDAY 670922 ONE O'CLOCK PM. NUMBER DOCUMENT 2481 AUTHOR* DOW ADDRESSEE* COPYEE* DATE 00/00/00 TYPE REPORT PAGES 1 DOCUMENT 2482 AUTHOR* DOW ADDRESSEE* DOW COPYEE* 09/11/67 MEMO F DICK F DAN 2 DOCUMENT 2483 00/00/75 NEWS 21 REPORT AUTHOR* DELVAUX EL DESART F UNIVERSITE CATHOLIQUE DE VERSTRAETE J ADDRESSEE* COPYEE* DOCUMENT 2484 00/00/00 AUTHOR* ADDRESSEE* COPYEE* BLACK C CRUMMETT W FREDERICK D JOHNS H MAIN R ROSS R TSCHIRLEY F WOLCOTT 0 REPORT 2 BLAIR E DAVIDSON JH GEHRING P JONES G MCCREDIE B ROWE VK VRANISH S DOCUMENT 2485 04/16/58 AUTHOR* DOW ADDRESSEE* COPYEE* DOW COLBY RW LIPPIE LJ ROWE VK REPORT HYMAS TA BARRONS KC COULTER LL LYNN GE SPALDING J 3 DOCUMENT 2486 AUTHOR* DOW ADDRESSEE* DOW COPYEE* 09/23/60 LETTER ROWE VK MAXWELL JL 2 DOCUMENT 2487 03/13/53 AUTHOR* DOW ADDRESSEE* DOW COPYEE* BRITTON JW LETTER ROWE VK SMITH HL JOHNSON JE 4 h -hhh'fT 4348 TITLE TCP REMOVAL PLAN JOB 71790. PAGE 356 199 BUILDING REMOVAL TRICHLOROPHENOL EQUIPMENT!JOB NO 7 1 7 9 0 ). LES POLYCHLORO DIBENZO-P-DIOXINS (TOX 3 ( 2 ) , 1 8 7 -2 0 6 ). GOFFIN G HAUTFENNE A TWELVE WISE MEN GIVE 24D AND 245T A CLEAN BILL OF HEALTH. BYRD B DAY B GRAHAM D KEARNEY P MORGAN A SCHWETZ B WARREN L COLBY R DONALDS J HOERGER F LENG M MOSS R TRAYNOR M WESELOH J INVERTON (BRUSH KILLER) HAY SPRAY, CATTLE FEEDING TEST (GH REPOT Ni 397). STEVENSON GT BLAIR EH JOHNSON JE NORTON TR VANVALKENBURG JW BOUNDY RH KAGY JF NUTTING HS TOXICOLOGICAL INFORMATION ON SILVEX AND GARLON CTTL. DISCUSSION OF TOXICOLOGICAL INFORMATION RELATIVE TO DOW ESTERON BRUSH KILLER. SOUTHWICK L NUMBER DATE DOCUMENT 2488 0 6 /2 7 /5 2 AUTHOR DOW ADDRESSEE BRYAN HL COPYEE TYPE PAGES LETTER 2 ROWE VK WEST MERCANTILE DOCUMENT 2489 AUTHOR DOW ADDRESSEE COPYEE 0 4 /0 0 /5 9 NEWS SEEKER B 3 DOCUMENT 2490 0 5 /0 6 /7 5 AUTHOR DOW ADDRESSEE COPYEE BRAUN WH HEEG KOCIBA RJ MCKENNA MJ POTTS WJ ROWE VK YOUNG REPORT 10 SAUERHOFF MW DAVIDSON JH HOOVER LEBEAU JE MURRAY FJ QUAST JF SCHWETZ BA DOCUMENT 2491 0 5 /2 1 /7 4 AUTHOR DOW ADDRESSEE DOW COPYEE BLAIR EH THEIS JM REPORT LENG ML DAVIDSON JH FE1GELSON MC TRAYNOR MJ 9 DOCUMENT 2492 0 6 /2 8 /7 7 AUTHOR DOW ADDRESSEE COPYEE BLAIR EH OLSON RD REPORT OTT MG 20 GLEESON JO 5CHARNWEBER HC DOCUMENT 2493 0 3 /0 2 /6 5 AUTHOR DEPT OF HEALTH MI ADDRESSEE DOW COPYEE LETTER 1 SCOVILL RG SILVERSTEIN L Vm s CO CD TITLE PAGE COMPOSITION OF DOW ESTERON BRUSH KILLER AND REQUEST FOR ALL INFORMATION REGARDING PENDING LAWSUIT CTTL. WESTERN MERCANTILE 357 END TO WATER WEEDS KURON OFFERS A CONTROL FOR UNWANTED VEGETATION IN LAKES AND PONDS (DOW DIAMOND). PHARMACOKINETIC STUDIES OF SILVEX IN MAN. GEHRING PJ HUMISTON CG LENG ML NORRIS RAMPY LW WATANABE PG GORDON HL JERSEY GC LEONG OLSON RAMSEY JC WOLF SILVEX AND ERBON DOW DOW LYNN GE WESSEL MR REGISTRATION AND TOXICOLOGY MCCOLLISTER DD WILLIAMS CS A LONGEVITY SURVEY OF EMPLOYEES EXPOSED TO 2A5TP 7 7 - 7 - 5 i 01. HOLDER BB WALKER S JOHNS DB EMPLOYEE MANAGEMENT MEETING ON 650119 CONCERNING PRECAUTIONS TO M INIM IZE TRICHLOROPHENOL CONTAMINANT EXPOSURE CTTL. 4350 JMBER DATE 2494 1 0 /0 3 /7 7 AUTHOR* BEYER JE ADDRESSEE* COPYEE* AXE RD BLAIR EH BROKER HH CAPUTO R DANIEL RL DELINE DD GEHRING PJ GRIESS GA HOERGER FD HYDE MA JOHNSON RL KIMMEL CE LEAVITT FC MAASBERG AT MCCLURE HH MCKENNA MJ MURRAY FJ NOLAN RJ OLSON KJ PUMPELLY CT RAMSEY JC ROBINSON VB SCHARNMEBER HC SHAVER RJ TRAYNOR M MACHOB MM YOUNG DJ DOCUMENT 2495 0 8 /1 0 /7 6 AUTHOR* DOM ADDRESSEE* DOM COPYEE* BLAIR EH GEHRING PJ SCHMETZ BA DOCUMENT 2496 0 8 /2 0 /7 9 AUTHOR* DOM ADDRESSEE* COPYEE* AXE RD BETSO JE BRAUNLICH FH CALDMELL CE CRUMMETT MB DAVIS RA ENGIBOUS DL GRAHAM DL HENRY H HYDE MA JOHNS DB KELLY ME TYPE PAGE REPORT 2 DOM BARNARD S BLOGG CD BUREK JD CARLETON RE DAVIDSON JD DIAGRE GM GETZENDANER M HALPHEN CE HOLDER BB JACKSON L JOHNSTON RV KOCIBA RJ LEBEAU JE MACGOMAN CF MCCOLLISTER DD MOOLENAAR RJ MURRAY N NORRIS JM OLSON RD QUAST JF REUVERS H ROGERS HA SCHNEIDER JA SHEETZ DP ULRICH JR MARNER SD YOUNG JD REPORT LENG ML SAUERHOFF MM BLAU GE GORDON HL REPORT SHARMA RP 4 BARNARD S BLAIR EH BROKER HH CAPUTO R DAIGRE GM DEGESERO RD GEHRING PJ GRIESS GA HOERGER FD JACKSON L JOHNSON RL KIMMEL CE TITLE PAGE 358 AN ULTRASTRUCTURAL EVALUATION OF LIVER CELLS ON DIETS CONTAINING TCDD. BEAMER WH BRAUN WH BURGERT BE CARLSON RG DAVIS RA DISHBURGER H GLEESON J HEFNER RE HORVATH BS JERSEY GC KELLY ME LANGNER RR LENG M MACKEY JC MCFEDRIES R MOORE JH NICHOLS JL NOWAK RM POTTS WJ RABOLD GP RINZEMA L ROWE VK SCHWETZ BA THOMPSON CF VERSCHUUREN H WATANABE PG BEARDEN CR BRUNLICH FH CALDWELL CE CRUMMETT WB DEGESERO RD ENGIBOUS DL GRAHAM DL HENRY H HUMISTON CO JOHNS DB KILIAN DJ LAPE RL LIU G MANSTON J MCINTIRE OR MURPHY PM NIELSEN WH NUMMY WR PRUITT ME RAMPY LW ROBERTS DJ SCHAFFER AW SERCU CL TODD LM VRANISH SM YOCUM RH REPORT ON SILVEX IN HUMANS. . CHENOWETH MB LEBEAU JE DAVIDSON JH MCCOLLISTER DD IMMUNOTOXICOLOGIC STUDIES INVOLVING TCDD IN MICE AND RABBITS. BEAMER WH BI.OGG CD BUREK JD CARL ETON RE DANIEL RL DELINE DD GETZENDANER ME HALPHEN CE HOLDER BB JERSEY GC JOHNSON S KOCIBA RJ BEARDEN CR BRAUN WH BURGERT BE CARLSON RG DAVIDSON JD DISHBURGER HJ GLEESON JG HEFNER RE HORVATH BS JOHN JA JOHNSTON RV LANGNERRR NUMBER DATE LAPE RL LIU G MANSTON J MCKENNA MJ NICHOLS JL NORRIS JM OLSON RD QUAST LF RAO KS ROBINSON VB SCHARNWEBER HC SERCU CL THOMPSON DJ VERSCHUUREN H WATANABE PG DOCUMENT 2497 0 2 /1 2 /7 3 AUTHOR: BOSSHARDT HP ADDRESSEE COPYEEi BLAIR EH LYNN GE STEHL RH DOCUMENT 2498 0 1 /1 8 /7 2 AUTHOR WILSON JG ADDRESSEE COPYEE DOCUMENT 2499 1 0 /0 6 /7 2 AUTHOR* DOW ADDRESSEE* COPYEE DOCUMENT 2500 1 2 /0 1 /7 5 AUTHOR DOW ADDRESSEE DOW COPYEE* SAUERHOFF MW DANIEL RL GEHRING PJ HEEG JF HUMISTON CG KILIAN DJ LENG ML MURRAY FJ PULLIN T RAPP DE SHOBER AE TORKELSON TR 4351 TYPE PAGES LEAVITT FC MAASBERG AT MCCLURE HH MOOLENAAR RJ NIELSEN WH NOWAK RM POTTS NJ RADOLD CP REUVERS H ROGERS WA SCHLACHTER MM SHAVER RJ TODD LM VRANISH SM YOCUM RH NEWS 9 NEUE ZRCHER ZT DAVIDSON JH OCONNOR JN WESSEL MR REPORT 5 ABSTRACT LEGAL REPORT SCHWETZ BA 4 REPORT 39 SAUERHOFF MW BLAIR EH BRAUM WH DAVIDSON JH GORDON HL HEFNER RE JENSEN DJ KOCIBA RJ MCCOLLISTER DD NORRIS JM QUAST JF ROWE VK SKORY LK WATANABE PG TITLE LEBEAU JE MACGONAN CF MCCOLLISTER DD MOORE JH NITSCHKE KD NUMMY HR PRUITT ME RAMPY LW RINZEMA LC ROWE VK SCHNEIDER JA SHEETZ DP TRAYNOR MJ HACHOB WW YOUNG DJ LENG ML MACKEY JC MCFEDRIES R MURRAY N NOLAN RJ OLSON KJ PUMPELLY CT RAMSEY JC ROBERTS DJ SCHAFFER AW SCHWETZ BA THOMPSON CF ULRICH JR WARNER SD DIOXINS - INSIDIOUS POISONS IN OUR ENVIRONMENT. FISHER P ROHE VK HANSEN JC SCHOBER AE PAGE 359 TERATOLOGICAL POTENTIAL OF 295T (DOWN TO EARTH 2 8 C9 ) 730900) (SOUTHERN HEED SCIENCE SOCIETY, DALLAS T X ). SUMMARY TERATOLOGY. THE DOSE - DEPENDENT PHARMACOKINETIC PROFILE OF SILVEX FOLLOHING INTRAVENOUS ADMINISTRATION IN RATS. BRAUN HH DISHBURGER HJ GORING CA HINMAN CH JERSEY GC LANGNER R MCKENNA MJ OLSON KJ RAMPY LH SCHARNWEBER HC SOUTHHICK L WATSON AJ BROWN S FIKE R GROVES K HOYLE HR JOHNSTON CV LEBEAU JE MULLISON HR OLSON RD RAMSEY JC SCHWETZ BA SHANK MG WOLF MA NUMBER DATE DOCUMENT 2505 0 8 /2 5 /7 1 AUTHOR* DOW ADDRESSEE COPYEE* BLAIR EH DUNN EE HUMISTON CG KOCIBA RJ MCCOLLISTER DD NUMMY WR REITZ RH SCHWETZ BA TORKELSON TR DOCUMENT 2506 0 9 /0 9 /7 0 AUTHOR: BOURNE JE ADDRESSEE COPYEE GEHRING PJ DOCUMENT 2507 1 0 /0 2 /7 0 AUTHOR ROWE VK ADDRESSEE COPYEE GEHRING PJ DOCUMENT 2508 1 1 /0 8 /7 8 AUTHOR: DOW ADDRESSEE* MT SINAI SCH MD COPYEE* BLAIR EH GEHRING PJ DOCUMENT 2509 0 5 /0 0 /7 8 AUTHOR* DOST FN ADDRESSEE* USDA FS COPYEE BETSO J LENG ML TRAYNOR MJ DOCUMENT 2510 0 2 /0 0 /7 8 AUTHOR* DOST FN ADDRESSEE* USDA FS COPYEE* DAVIDSON JH MORGAN A DOCUMENT 2511 0 6 /0 3 /7 4 AUTHOR: DOW ADDRESSEE* DOW COPYEE* BLAIR EH TRAYNOR MJ TYPE PAGES REPORT PIPER WN 1 BLUE RD GEHRING PJ JOHNSON JE LENG ML MCCOLLISTER SB ORIEL PJ RILEY WH SMITH GN WOLF MA REPORT DON NORRIS JM A AUTH 2 LETTER ROWE VK SELIKOFF IJ CRUMMETT WB HOLDER BB 2 REPORT 139 OR STATE UNIV DAVIDSON JH MCCOLLISTER DD REPORT 73 OR STATE UNIV HOLDER B SCHWETZ B REPORT WOLF MA LYNN GE CRUMMETT WB WESSEL MR 5 f i- k f t f r ( , 4352 TITLE PAGE EXCRETION AND TISSUE DISTRIBUTION OF TCDD IN THE RAT 1. 361 BRANSON DR HINMAN CH JOHNSTON C LEONG BK MCDERMOTT RD OSBORNE DH ROSE J SPENCER HC CHENOHETH MB HOLMSEN TH JOHNSTON RV MCCARTY LP MOSS RD PRUITT ME ROHE VK STRYCKER SJ PROPOSED ACUTE ORAL LD50 FEEDING STUDY ON THO SAMPLES OF TCDD. ROHE VK TCDD (REQUEST FOR PRELIMINARY TOXICOLOGICAL STUDIES) CTTL. SEMINAR ON PHENOXY HERBICIDES BACKGROUND PLANNING CTTL. DAVIDSON JH KOCIBA RJ DONALDS JE SCHHETZ BA TOXICOLOGY OF PHENOXY HERBICIDES AND HAZARD ASSESSMENT OF THEIR USE IN REFORESTATION. USDA KOCIBA RJ SCHHETZ BA LEISZ DR SMITH LL TOXICOLOGY OF PHENOXY HERBICIDES AND TCDD. JOHNSON R HARREN LE KOCIBA R TOXICOLOGY OF POSSIBLE CONTAMINANTS IN 2A5T. DON DON DAVIDSON J GEHRING PJ DOH  ftfr /r-< . NUMBER DOCUMENT 2512 DATE 0 0 /0 0 /7 3 AUTHOR ALLEN JR UNIV OF HI ADDRESSEE* COPYEE* DOCUMENT 2513 0 8 /2 0 /7 9 AUTHOR* DOH ADDRESSEE* COPYEE* AXE RD BETSO JE BRUNLICH FH CALDWELL CE CRUMMETT WB DAVIS RA ENGIBOUS DL GRAHAM DL HENRY H HYDE MA JOHNS DB KELLY ME LAPE RL LIU G MANSTON J MCKENNA MJ NICHOLS JL NORRIS JM OLSON RD QUAST JF RAO KS ROBINSON VB SCHARNWEBER HC SERCU CL THOMPSON DJ VERSCHUUREN H WATANABE PG DOCUMENT 2514 1 0 /0 8 /7 1 AUTHOR* BLOSSER K MOSS RD ADDRESSEE* COPYEE* DOCUMENT 2515 AUTHOR* DOW ADDRESSEE* COPYEE* 0 0 /0 0 /6 7 TYPE REPORT PAGES FIRESTONE D REPORT SHARMA RP BARNARD S BLAIR EH BROWER HH CAPUTO R DAIGRE GW DEGESERO RD GEHRING PJ GRIESS GA HOERGER FD JACKSON L JOHNSON RL KIMMEL CE LEAVITT FC MAASBERG AT MCCLURE HH MOOLENAAR RJ NIELSEN WH NOWAK RM POTTS WJ RABOLD CP REUVERS H ROGERS HA SCHLACHTER MM SHAVER RJ TODD LM VRANISH SM YOCUM RH REPORT TEST DOH WOLF MA LABEL TITLE PAGE 362 STUDIES OF THE CHICK EDEMA DISEASE TOXICITY OF CHICK EDEMA FACTORS IN THE CHICK CHICK EMBRYO AND MONKEY (POULTRY SCIENCE 52, 1637-1641). FLICK DF RESS J REVERSAL OF IMMUNOLOGIC AND TOXICOLOGIC EFFECTS OF A SINGLE EXPOSURE OF TCCD IN MICE. DOM BEAMER MH BLOGG CD BUREK JD CARL ETON RE DANIEL RL DELINE DD GETZENDANER M HALPHEN CE HOLDER BB JERSEY GC JOHNSON S KOCIBA RJ LEBEAU JE MACGOMAN CF MCCOLLISTER DD MOORE JH NITSCHKE KD NUMMY HR PRUITT ME RAMPY LH RINZEMA LC ROME VK SCHNEIDER JA SHEETZ DP TRAYNOR MJ MACHOB MH YOUNG DJ BEARDEN CR BRAUN MH BURGERT BE CARLSON RG DAVIDSON JD DISHBURGER HJ GLEESON JG HEFNER RE HORVATH BS JOHN JA JOHNSTON RV LANGNER RR LENG ME MACKEY JC MCFEDRIES R MURRAY N NOLAN RJ OLSON KJ PUMPELLY CT RAMSEY JC ROBERTS DJ SCHAFFER AH SCHMETZ BA THOMPSON CF ULRICH JR MARNER SD ANALYTICAL METHOD REDDON BRUSH KILLER (METHOD 7 0 8 4 9 ). KOERKER FM LOUCKS MF KURON MEED AND BRUSH KILLER NUMBER DATE DOCUMENT 2516 0 0 /0 0 /0 0 AUTHOR: CHIPMAN ADDRESSEE COPYEE DOCUMENT 2517 AUTHOR THA ADDRESSEE COPYEE 0 0 /0 0 /0 0 DOCUMENT 2518 0 0 /0 0 /7 1 AUTHOR BJORKLUND N ADDRESSEE COPYEE DOCUMENT 2519 0 0 /0 0 /6 6 AUTHOR ERNE K ADDRESSEE: COPYEE DOCUMENT 2520 0 0 /0 0 /6 3 AUTHOR ERNE K ADDRESSEE COPYEE DOCUMENT 2521 AUTHOR: DOW ADDRESSEE COPYEE 0 3 /2 9 /7 8 DOCUMENT 2522 AUTHOR: DOW ADDRESSEE COPYEE DOCUMENT 2523 AUTHOR DOW ADDRESSEE COPYEE 0 2 /1 4 /7 4 1 1 /0 2 /7 8 TYPE LABEL PAGES 1 TITLE PAGE LOW VOLATILE BRUSH KILLER NO. 2 ( CHIPMAN)(PRODUCT 1 1 2 ). 363 LABEL 1 DED-2 LV-9 BRUSH KILLER. REPORT ERNE K 15 PHENOXY-ACID-INDUCED RENAL CHANGES IN THE CHICKEN. 1. ULTRASTRUCTURE (ACTA VET. SCAND. 1 2, 2 4 3 -2 5 6 ). NATL VETERINARY INST SWE ROYAL VETERINARY COL SWE REPORT 18 DISTRIBUTION AND ELIMINATION OF CHLORINATED PHENOXYACETIC ACIDS IN ANIMALS (ACTA VET SCAND 7 , 2 4 0 -2 5 6 ). NATL VETERINARY INST SWE REPORT 15 DETECTION AND DETERMINATION OF CHLOROPHENOXYACETIC ACID DERIVATIVES IN WATER. (ACTA CHEM. SCAND. 1 7 ( 6 ) , 1 6 6 3 -1 6 7 6 ). ST VETERINARY MED INST S CHART WHITE RW 1 FINNIGAN 400 MASS SPECTROMETER L S I-1 1 BACK PANEL LAYOUT. TEST 14 DETERMINATION OF TCDD IN FISH AND SOIL. TEST 32 STACK GAS SAMPLING PROCEDURE FOR THE DETERMINATION OF CHLORINATED DIOXIN EMISSIONS FROM STATIONARY SOURCES (ML-AM 7 8 - 6 4 ). OS/r/rrf CO err NUMBER DOCUMENT 2524 AUTHOR DON ADDRESSEE DNR MI COPYEE DATE 0 6 /0 9 /7 8 DOCUMENT 2525 AUTHOR DOW ADDRESSEE COPYEE 0 4 /0 0 /7 1 DOCUMENT 2526 AUTHOR DOW ADDRESSEE COPYEE DOW 0 2 /2 2 /6 5 DOCUMENT 2527 1 0 /1 0 /7 8 AUTHOR DOW ADDRESSEE COPYEE: DOCUMENT 2528 0 6 /2 2 /7 8 AUTHOR: ADDRESSEE COPYEE DOCUMENT 2529 AUTHOR: DOW ADDRESSEE COPYEE: 1 1 /2 8 /7 7 DOCUMENT 2530 1 2 /3 0 /6 4 AUTHOR: DOW ADDRESSEE DOWNARD GM COPYEE DOW DOCUMENT 2531 AUTHOR: DOW ADDRESSEE COPYEE: 1 1 /0 0 /6 7 TYPE PAGES LETTER 16 GLEDHILL JR HESSE J NEWS WILLIAMS CS 6 MINUTES PLETCHER DE DOEDENS JD 3 TEST 25 REPORT 5 TEST 7 LETTER HAMMER OH USDA LYNN GE LABEL 1 1 J )- W S! 4355 TITLE PAGE 364 REPORT ON STUDIES RELATED TO THE QUESTION OF POSSIBLE PRESENCE OF CHLORODIOXINS IN TITTABANASSEE RIVER SEDIMENTS & FISH CTTL. THE STATUS OF 24D, 245T, SILVEX AND MCPA HERBICIDES (DOWN TO EARTH 26(4) 12-15, 1971). EXCITER PROBLEM MEETING 650218. DETERMINATION OF TETRA, HEXA, HEPTA, AND OCTACHLORODIBENZO-P-DIOXINS IN SOL SOIL, DUST, AND PARTICULATE SAMPLES. ENVIRONMENTAL SAMPLING AND ANALYSIS PLAN FOR THE EVALUATION OF ORGANIC RESIDUES IN FISH OF THE TITTABAWASSEE AND SAGINAW RIVERS AND THE SAGINAW BAY. DETERMINATION OF TCDD IN WIPE TEST'SAMPLES ANALYTICAL METHOD (ML-AM 77-51). PROPOSED USE OF KURON ON SUGAR CANE IN FL (KURON REGISTRATION 464-162). SACHS SB SUNDERLAND WW KURON WEED AND BRUSH KILLER. NUMBER DATE DOCUMENT 2576 07/14/82 AUTHOR SCHOBER AE ADDRESSEE EPA COPYEE* ROSS E TYPE PAGES LETTER 1 DOH MOUNTFORT R BUZZELLI D DOCUMENT 2577 06/14/82 AUTHOR EPA ADDRESSEE SCHOBER AE COPYEE LETTER MOUNTFORT RF DOW 1 DOCUMENT 2578 05/30/80 AUTHOR KOCIBA RJ OLSON KJ ADDRESSEE COPYEE CHART DATA REPORT DOW RAO KS 30 DOCUMENT 2579 05/30/80 AUTHOR KOCIBA RJ OLSON KJ ADDRESSEE WESELOH JW COPYEE KOCIBA RJ CAPUTO R HENK JW LOCKWOOD DD CHART DATA REPORT DOW RA 0 KS SCHWETZ BA CHENOWETH MB KOLESAR RC MORRISON LG 3 DOCUMENT 2580 02/08/72 AUTHOR JOHNSON JE ADDRESSEE COPYEE REPORT DOW 40 DOCUMENT 2581 AUTHOR DOW ADDRESSEE' COPYEE 08/03/82 PROC TECH MUJICA ML 8 DOCUMENT 2582 08/08/83 LEGAL AUTHOR DOW ADDRESSEE REPUBLICA COSTA RICA COPYEE FALLA EC 1 -t$ b b CO or en TITLE PAGE ESTERON 245 BE, EPA REG 464-574, YOUR LETTER OF MAY 13, 1982 (820513). 371 CONYERS E DESCRIPTION OF ANALYTICAL METHOD FOR TCDD, ESTERON 245 BE EPA REGISTRATION 464-574, YOUR SUBMISSION OF JULY 14, 1982 (820714). TCDD ACUTE ORAL TOXICITY IN HAMSTERS. HENCK JH NEW MA TCDD ACUTE ORAL TOXICITY IN HAMSTERS. HENCK JH NEW MA BOHL RA DOMBROHSKI SA KOPPELMANN H OLSON RA BRANSON FISHBECK H LANHAM JM RAMPY LW HERBICIDES. ANALYTICAL METHOD ESTERON 245C HERBICIDE. CERTIFICATE FOR DIOXIN CONTENT IN ESTERON 245, ESTERON C, ESTERON 50-25 CTTL. CARLSON KS NUMBER DATE DOCUMENT 2583 04/00/83 AUTHOR DOM ADDRESSEE* PERCOSSI H COPYEE* DOCUMENT 2584 AUTHOR* DOM ADDRESSEE* COPYEE* 00/00/83 DOCUMENT 2585 AUTHOR* DOM ADDRESSEE* COPYEE* 07/28/83 DOCUMENT 2586 AUTHOR* DOM ADDRESSEE* COPYEE* 08/03/83 DOCUMENT 2587 AUTHOR* DOM ADDRESSEE* COPYEE* 00/00/83 DOCUMENT 2588 12/09/80 AUTHOR* BRAUN MH HERMANN EA ADDRESSEE* DOM COPYEE* BRAUN MH MCCOLLISTER DD SHEETZ DP DONALDS JE LUOMA EV SCHMETZ BA DOCUMENT 2589 12/09/80 AUTHOR* NOLAN RJ RAMSEY JC ADDRESSEE* DOM COPYEE* LOOK AT MCCLURE HH 1 MOOLENAAR RJ NUMMY HR RAMPY LH CO REUVERS or SAUNDERS JH TALCOTT AT TYPE PAGES MEMO MESTRE S 1 MEMO 1 TELECON 1 HOODHARD RE SPEC TEST CERASO JM 1 LEGAL 1 REPORT TEST NOLAN RJ RAMSEY JC 34 CRUMMETT HB NOLAN RJ VERSCHUUREN HG; GEHRING PJ SCHAFFER AM MATSON AJ ABSTRACT DOM 1 LYONS KL MCDANIELS GD NENDY HE OLSON KJ RAMSEY JC RINZEMA SCHNEIDER EJ THOMPSON CF TITLE COMMENTS ON ESTERON 245 & TORDON 225E CTTL. COMMENTS ON TORDON 225E & ESTERON 245 CTTL. COMMENTS ON SAMPLE OF ESTERON 245 C CTTL. CERTIFICATE OF ANALYSIS FOR ESTERON 245 CTTL PAGE 372 CERTIFICATE FOR DIOXIN CONTENTS IN ESTERON 245 CTTL. PHARMACOKINETICS OF 24D IN FISCHER 344 RATS DOW HOOVER WE SMITH FA HEFNER RE NORRIS JM VRANISH SR; KOCIDA RJ SCHARNWEBER HC WESELOH JW HOERGER FD OLSON RD DAVIDSON JH LENG ML SCHOBER AE PHARMACOKINETICS OF 24D IN FISCHER 344 RATS SMITH FA HERMANN EA MACGOWAN CF MCFEDRIES R JR NICHOLS JL PARENTI F RAO KS ROGERS WA SHELTON LG TOD LM MACKEY JC MCKENNA MJ NOWAK RM PUMPELLY CT RAUSCH DA ROZAS EA SWANK MG VENABLE JR NUMBER DATE WARNER SD YOCUM RH GORZINSKI SJ HOOVER ME KAGEl RO LANCINI G LEHMAN FR BEARDEN CR BURGESS KL CORSON FP DICKSON G FISHBECK HA TYPE PAGES HATANABLE YOUNG DM GRAHAM DL HYLTON DB KELLY ME LANGNER RR LIU G BRADLEY TD CALDWELL BG CURRIER MF DOSTAL RL FLORES GF DOCUMENT 2590 00/00/82 AUTHOR KOCIBA RJ ADDRESSEE COPYEE NEWS REPORT SCHWETZ BA 20 DOCUMENT 2591 AUTHOR DOM ADDRESSEE COPYEE 11/09/81 LABEL 2 DOCUMENT 2592 AUTHOR ADDRESSEE COPYEE* 11/09/81 AUTH LABEL 1 DOCUMENT 2593 AUTHOR ADDRESSEE COPYEE* 11/09/81 AUTH 1 DOCUMENT 259A 11/09/81 AUTHOR* SCHOBER AE ADDRESSEE* EPA COPYEE LANINO ER LETTER DOM MOUNTFORT R MOODS CD 1 DOCUMENT 2595 03/02/82 LETTER AUTHOR MARSHALL FARMERS COOP HOLLIDAY V ADDRESSEE COPYEE 1 5 AAv 07 CO TITLE WRIGHT LF GAY PC HALPHEN CE JACKSON JE KLUMB GA LANHAM JM ADCOCK LD BRUNLICH FH CAPUTO R DANIEL RL EILERS RJ WROBLEWSKI DJ GERARDO RA HERMANN EA JERSEY GC KOLESAR RC LEE JR AXE FD BURGERT BE CHEN WC DAVIS KR ENGIBOUS DL PAGE 373 TOXICITY OF TCDD (DRUG METABOLISM REVIEWS 13(3), 387-406). DOW ESTERON 245 HERBICIDE. ESTERON 245BE LABEL TECHNICAL DATA. ESTERON 245BE CERTIFICATION STATEMENT. ESTERON 245BE APPLICATION FOR NEW REGISTRATION. GOODMAN CH YTZEN GL NOTICE OF SUSPENSION FROM SALE. ESTERON 245T. DEPT AG & IND AL NUMBER DATE TYPE PAGES DOCUMENT 2596 03/2A/82 LETTER AUTHOR* DOW CONTINO JG ADDRESSEE* MARSHALL FARMERS CO-OP COPYEE* 1 DOCUMENT 2597 02/19/82 AUTHOR* SAFE S BANDIERA S ADDRESSEE* COPYEE* REPORT 13 ROBERTSON L SAFE L DOCUMENT 2598 00/00/00 AUTHOR* POIGER H ADDRESSEE* COPYEE* BRAUN WH WATANBE P REPORT TECH BUSER HR GEHRINO PJ RAO KS 11 DOCUMENT 2599 11/00/81 AUTHOR* DRENCKPOHL JW ADDRESSEE* COPYEE* SPEC YTZEN J 1 DOCUMENT 2600 03/25/82 AUTHOR* DRENCKPOHL JW YTZEN GL ADDRESSEE* COPYEE* SPEC GANTZ RL SCHULTZ J 1 DOCUMENT 2601 09/23/80 AUTHOR* ADDRESSEE* COPYEE* COOK RR SCHOBER AE ISENBARGER B SPEC 3 DRENCKPOHL JW WOODS J KING EJ DOCUMENT 2602 OA/16/82 AUTHOR* WOODS J ADDRESSEE* COPYEE* SPEC 2 DOCUMENT 2603 10/16/81 , AUTHOR* DOW W \ ADDRESSEE* \J COPYEE* DRENCKPOHL JW A SKURSKI M SPEC WOODS J GANTZ RL ISENBARGER B 1 & SS \ CO TITLE PAGE 374 STICKER & COPY OF LATEST SPECIMEN LABEL FOR ESTERON 245 CTTL. PCDDS 8 RELATED COMPOUNDS - METABOLISM AND BIOCHEMISTRY. SAWYER T PARKINSON A CAMPBELL M STRUCTURE ELUCIDATION OF MAMMALIAN TCDD METABOLITES. SCHWETZ BA RAMSEY J SALES SPECIFICATION. ESTERON 245 BE HERBICIDE. ISENBARGER B SALES SPECIFICATION. ESTERON 245 BE HERBICIDE. CONTINO J WOODS JS PRODUCTION SPECIFICATION. ESTERON 245 BE HERBICIDE. GANTZ RL TICHON J GLEDHILL JR SKURSKI M MFG SPECIFICATION. ESTERON 245 BE HERBICIDE. MFG SPECIFICATION. ESTERON 245 BE HERBICIDE. GLEDHILL JR TICHON J HUMBER DATE DOCUMENT 2604 04/13/82 AUTHOR DRENCKPOHL JW SCHULTZ J ADDRESSEE COPYEE DOCUMENT 2605 03/00/82 AUTHOR GLEDHILL JR ISENBURGER B ADDRESSEE COPYEE DOCUMENT 2606 05/24/82 AUTHOR DRENCKPOHL JW DOW SKURSKI MJ ADDRESSEE COPYEE DOCUMENT 2607 04/05/83 AUTHOR DELISLE NG ADDRESSEE COPYEE DOCUMENT 2608 04/05/83 AUTHOR DRENCKPOHL JW ADDRESSEE* COPYEE DOCUMENT 2609 AUTHOR DOW ADDRESSEE* COPYEE 02/02/82 DOCUMENT 2610 04/08/82 AUTHOR* DRENCKPOHL JW ROLDAN J RUIZ A ADDRESSEE* COPYEE TYPE PAGES SPEC 2 GANTZ RL CONTINO J SPEC DOW 2 SPEC GANTZ RL GOLD WL WOODS JS 2 PRINT 1 SPEC DRENCKPOHL JW PRINT SPEC DOW 1 SPEC 1 PRINT SPEC GOLD WL RAMIREZ C ORLANDI A 2 CO 05 O TITLE QUALITY ASSURANCE PRODUCTION SPECIFICATION. HERBICIDE. SCHOBER AE DOW I DWD PAGE ESTERON 245 BE 375 QUALITY ASSURANCE PRODUCTION SPECIFICATION. ESTERON 245 BE HERBICIDE. TICHON JM SHURSHI MJ QUALITY ASSURANCE PRODUCTION SPECIFICATION. HERBICIDE. GLEDHILL JR SCHOBER AE ISENBARGER B TICHON JM SCHULTZ JA CONTINO JG ESTERON 245 BE ESTERON 245 BE HERBICIDE RAW MATERIAL SPECIFICATION CTTL. DOW GOLD WL ESTERON 245 BE HERBICIDE RAW MATERIAL SPECIFICATION CTTL. GOLD WL PRODUCTION SPECIFICATION FOR ESTERON 245C HERBICIDE. ESTERON 245C HERBICIDE PRODUCT SPECIFICATION CTTL. WOODS JS DEMUJICA MLB GILCHRIST J CASTRO A K^.iBER DATE DOCUMENT 2611 07/27/82 AUTHOR DRENCKPOHl JW HOODS JS DEMUJICA MLB ADDRESSEE' COPYEE DOCUMENT 2612 AUTHOR ADDRESSEE COPYEE 03/01/83 DOCUMENT 2613 00/00/81 AUTHOR FAGAN ADDRESSEE KOCIBA RJ COPYEE DOCUMENT 2614 AUTHOR ADDRESSEE COPYEE 08/00/83 DOCUMENT 2615 08/00/83 AUTHOR CHARLTON RM ADDRESSEE COPYEE DOCUMENT 2616 00/00/77 AUTHOR NAS LOMERRE RH ADDRESSEE COPYEE DOCUMENT 2617 AUTHOR' DOM ADDRESSEE COPYEE 04/22/83 DOCUMENT 2618 03/19/82 AUTHOR DOM ADDRESSEE SCHOBER AE COPYEE GOODMAN CH TYPE PAGES PRINT SPEC FRASER JM GILCHRIST J CASTRO A 3 LABEL 1 REPORT POLLAR JK 49 REPORT 33 REPORT DOM 2 REPORT KARCH NJ MCCRAY LE 6 TEST GIRARDlN D 1 LETTER BUZZELLI DT DOM TICHON J 2 /A-CL CO cn GE 376 Tn ESTEROM 245C HEARBICIDE QACACI SPECIFICATION CONFIRMATION CTTL DOW ROLDAN J RUIZ A GOLD ML RAMIREZ C ORLANDI A ESTERON 245 BE LABEL CTTL. THE EFFECT OF THE PHENOXYACETIC ACID HERBICIDES 245T 24D AS ASCERTAINED BY DIRECT EXPERIMENTATION. UNIV OF SYDNEY AUSTRAL DIOXIN & HUMAN HEALTH. DOM HEALTH ENVIRONMENTAL INFORMATION DIOXIN * HUMAN HEALTH EXECUTIVE SUMMARY. DECISION MAKING IN THE EPA. BURT RE KASPER RG ARNOLD JR DETERMINATION OF TCDD IN ESTERON 245 BRUSH MEED KILLER. I JMC ESTERON 245 BE-TCDD ANALYSIS. NUMBER DATE DOCUMENT 2619 11/05/81 AUTHOR GANTZ RL ADDRESSEE TOWNSEND J COPYEE DOCUMENT 2620 02/21/83 AUTHOR DOM ADDRESSEE GANTZ RL COPYEE SCHOBER. AE DOCUMENT 2621 02/16/83 AUTHOR GANTZ RL ADDRESSEE DOM COPYEE LANING ER DOCUMENT 2622 02/23/83 AUTHOR GANTZ RL ADDRESSEE DOW COPYEE DOCUMENT 2623 AUTHOR DOM ADDRESSEE COPYEE 05/19/82 DOCUMENT 2624 04/21/78 AUTHOR EPA ADDRESSEE COPYEE DOCUMENT 2625 07/00/72 AUTHOR LENG ML ADDRESSEE COPYEE DOCUMENT 2626 02/00/79 AUTHOR LENG ML i , ADDRESSEE VJ COPYEE TYPE MEMO DOM PAGES 1 MEMO 1 HAVEL JJ DOW 1 MEMO DOM HAVEL JJ SCHOBER AE MEMO DOM YTZEN GL 1 1 TECH 3 LEGIS 36 NEWS DOM REPORT DOM 9 2 ^ CO oe,' to TITLE PAGE CONCERNS MATERIAL SAFETY DATA SHEET FOR ESTERON 245 CTTL. 377 USE DIRECTIONS FOR ESTERON 245BE (EARLY 1982 C820000) PRODUCTION). FIELD SOLUTION TO PRESCRIBE FOR ESTERON 245 BE HERBICIDE QUALITY COMPLAINTS. TICHON JM YTZEN GL MIXING GUIDELINES FOR UTILIZING PREVIOUSLY UNRETURNED ESTERON 245 BE HERBICIDE IF QUALITY COMPLAINTS ARISE IN 1983 (830000). ESTERON 245BE HERBICIDE MATERIAL SAFETY DATA SHEET. PESTICIDES PROGRAMS REBUTTABLE PRESUMPTION AGAINST REGISTRATION 8 CONTINUED REGISTRATION OF PESTICIDE PRODUCTS CONTAINING 245T (FED REGISTER 43(78), 17116-17147). RESIDUES IN MILK 8 MEAT 8 SAFETY TO LIVESTOCK FROM THE USE OF PHENOXY HERBICIDES IN PASTURE 8 RANGELAND (DTE 28(1), 12-20). SUMMARY OF DOM'S RESPONSE TO ERA'S RISK ANALYSIS ON THE USE OF 245T HERBICIDE. NUMBER DOCUMENT 2627 AUTHOR: ADDRESSEE COPYEEs DATE 10/25/81 TYPE ABSTRACT PAGES 1 DOCUMENT 2628 00/00/69 AUTHOR: LENG ML ADDRESSEE COPYEE NEWS 1 MCCOLLISTER DD DOCUMENT 2629 00/00/81 AUTHOR: REUBER MD ADDRESSEE COPYEE NEWS 1 DOCUMENT 2630 05/20/81 LETTER AUTHOR JOUR OF TOXICOLOGY 8 ENV ZWEIG G ADDRESSEE KOCIBA RJ DOW COPYEEs 1 DOCUMENT 2631 AUTHOR LE ADDRESSEE COPYEE 04/29/81 MEMO 1 DOCUMENT 2632 AUTHOR ACS ADDRESSEE COPYEE 08/26/80 PRESENT 1 DOCUMENT 2633 00/00/81 AUTHOR HUMMEL RA DOW ADDRESSEE COPYEE NEWS JENSEN DJ HIGGINS HS 1 DOCUMENT 2634 11/00/79 AUTHOR POIGER H ADDRESSEE COPYEEs NEWS SCHLATTER C 1 -i. CO cn> TITLE SEVESO-AN ENVIRONMENTAL ASSESMENT. AGE 378 TOXICOLOGY OF PICLORAM 8 EVALUATION OF TORDON HERBICIDES. DOM CARCINOGENICITY OF PICLORAM. CONFLICTING VIEWS ON PICLORAM TOXICITY CTTL. MCCUTCHEON RS REPLY OF THE FEDERAL GOVERNMENT RELATING TO 2A5T HERBICIDES CTTL. THE RESPONSIBILITY OF THE CHEMIST TO SOCIETY. RESIDUE STUDY ON BEEF CATTLE CONSUMING 2378 TCDD. KOCHER CM MAHLE NH INFLUENCE OF SOLVENTS & ADSORBENTS ON DERMAL 8 INTESTINAL ABSORPTION OF TCDD. UNIV OF ZURICH SMITZ FED-INST OF TECH SHITZ NUMBER DATE DOCUMENT 2635 00/00/72 AUTHOR: LENG ML ADDRESSEE* COPYEE* DOCUMENT 2636 02/00/82 AUTHOR* BRAUN WH LAVY TL ADDRESSEE* COPYEE* DOCUMENT 2637 04/29/81 AUTHOR* LENG ML ADDRESSEE* COPYEE* DOCUMENT 2638 AUTHOR* ADDRESSEE* COPYEE* 00/00/73 DOCUMENT 2639 05/30/74 AUTHOR* GEHRING PJ ADDRESSEE* COPYEE* BLAIR EH JOHNSON JE LYNN GE ROBINSON VB TRAYNOR MJ K1MMEL CE SHAVER RJ RINZEMA L ROSE JQ DOCUMENT 2640 05/30/74 AUTHOR* GEHRING PJ ADDRESSEE* COPYEE* TYPE NEWS DOW PAGES TITLE PAGE 379 RESIDUES IN MILK * MEAT & SAFETY TO LIVESTOCK FROM THE USE OF PHENOXY HERBICIDES PASTURE 8 RANGELAND. DTE REPORT LENG ML UNIV OF AR REVIEW OF STUDIES WITH 245T IN HUMANS INCLUDING APPLICATORS UNDER FIELD CONDITIONS. DOW RAMSEY JC PRESENT 1 MCCOLLISTER DD PRODUCT REGISTRATIONS 8 NOTIFICATIONS-PESTICIDES. DOW DATA REPORT 10 TERATOGENICITY OF PESTICIDES, THEIR METABOLITES AND CONTAMINANTS. r REPORT KOCIBA RJ 3 2378-TETRACHL0R0DIBENZ0-P-DI0XIN (TCDD), RESULTS OF A 13 WEEK ORAL TOXICITY STUDY IN RATS. KEELER RJ DAVIDSON JH KILIAN DJ MCCOLLISTER DD ROWE VK WESSEL MRjKAYE SCHOLER FREVEL LK HOUSE RJ MOOLENAAR RJ YATES WM GORDON HL LENG ML NORRIS JM SCHWETZ BA PRUITT ME BURGERT BE LEAVITT FC PULLIN T MCCUTCHEON SM HOLDER BB LICHY CT OLSON RD SPENCER HC MCINTYRE HH HORVATH B CARLETON R KIN S CHART REPORT KOCIBA RJ 97 2378-TETRACHL0R0DIBENZ0-P-DI0XIN (TCDD), RESULTS OF 13 WEEK ORAL TOXICITY STUDY IN RATS. DOW KEELER PA o)}th-, CO CD NUMBER DOCUMENT 2641 DATE 00/00/78 TYPE REPORT PAGES 7 AUTHOR HARDELL L ADDRESSEE COPYEE DOCUMENT 2642 AUTHOR DOM ADDRESSEE COPYEE 03/00/82 SANDSTROM A LABEL 2 DOCUMENT 2643 03/24/82 AUTHOR SCHOBER AE ADDRESSEE EPA COPYEE LANING ER ROSS E LETTER DOM ADAMCZYK TE BUZZELLI DT 2 DOCUMENT 2644 AUTHOR ADDRESSEE COPYEE 00/00/00 REPORT 3 DOCUMENT 2645 00/00/00 REPORT 6 AUTHOR ADDRESSEE COPYEE DOCUMENT 2646 12/13/82 AUTHOR KILPATRICK R ADDRESSEE MALKER D COPYEE LETTER DOCUMENT 2647 02/07/83 NEMS AUTHOR MINISTRY OF AO FISHERIES ADDRESSEE COPYEE 4 2 TITLE PAGE 380 CASE CONTROL STUDY. MALIGNANT MESENCHYME SOFT TISSUE TUMOUR EXPOSE TO PHENOXY ACIDS OR CHLOROPHENOLS (LAKARTIDNINGEN 75(40) 1978 (780000). ESTERON 245BE HERBICIDE. ESTERON 245BE EPA REG 464-574 YOUR LETTER OF MARCH 16, 1982 (820316). GOODMAN C CONYERS E PROPOSALS FOR EPIDEMIOLOGICAL INVESTIGATIONS OF MORBIDITY ASSOCIATED WITH HERBICIDES. SUMMARY OF EPIDEMIOLOGICAL & CLINICAL STUDIES CONTRIBUTING ORIGINAL OBSERVATIONS CONCERNING A POSSIBLE ASSOCIATION BETWEEN CHEMICAL EXPOSURE & SOFT TISSUE SARCOMAS. EVIDENCE CONCERNING THE SAFETY OF 245T HERBICIDES CTTL. ADVISORY COMMITTEE ON PESTICIDES, REPORT ON PHENOXYL ACID HERBICIDES. NUMBER DATE DOCUMENT 2648 06/09/81 AUTHOR* HUNTER HCD KELLY J ADDRESSEE* COPYEE* DOCUMENT 2649 08/28/80 AUTHOR* WARREN LE ADDRESSEE* SWEELEY JB COPYEE* ALLISON WE HUNT DD DOCUMENT 2650 AUTHOR* ADDRESSEE* COPYEE* 06/23/72 DOCUMENT 2651 05/01/80 AUTHOR* DOW ADDRESSEE* COPYEE* LANING ER DOCUMENT 2652 AUTHOR* ADDRESSEE* COPYEE* 06/24/80 DOCUMENT 2653 AUTHOR* ADDRESSEE* COPYEE* 06/24/80 DOCUMENT 2654 10/07/77 AUTHOR* LENO ML ADDRESSEE* ALBERG COPYEE* DAVIDSON JH SEWARD WB DAAK D TYPE PAGES TITLE REPORT 42 A REPORT ON 24D, 245T 8 HUMAN HEALTH. TEST RATHUS E DONOHUE J OXENHAM B LAND ADMIN COMM AUSTRAL PAGE 381 LETTER SPEC DOW MASONITE DAVIDSON JH JONES J 2 REPORT TEST 40 REMARKS ON 24D & 245T IN RELATION TO CHLORACNE C T T L . NORRIS MG ANDERSON M WATSON AJ PARKER N DOW EPA HEARING. SUBMISSIONS RE* CANCELLATION - VOLUME 2 2 4 5 T . REPORT 37 24D. EVALUATION OF THE HUMAN HEALTH HAZARDS. DEPT OF HEALTH SERVICES NEWS 1 STATE WARNING ON 24D HERBICIDE EXPOSURE ISSUED. NEWS 2 24D MAY CAUSE LONG LASTING NERVE DAMAGE CTTL. LETTER 2 SAFETY OF HANDLING DOW 24D AND MCP PRODUCTS CTTL. DOW MIDLAND COOPERATIVES DRENCKPOHL JW HEIN ND JANTZ OK SMITH LL TRAYNOR MJ WILLIAMS CS 'O bb' O 05 NUMBER DATE RINZEMA L IRON HATKINS DOCUMENT 2670 03/07/83 AUTHOR DOW MOOLENAR RJ ADDRESSEE COPYEE GANTZ RL DOCUMENT 2671 05/21/82 AUTHOR DOW ADDRESSEE HOLZSCHU RG SCHULTZ JA COPYEE DOW DOCUMENT 2672 08/25/81 AUTHOR GANTZ RL FLANNERY RF ADDRESSEE COPYEE DOW DOCUMENT 2673 01/12/82 AUTHOR BLACK MD ADDRESSEE COLBY RW COPYEE EPA DOCUMENT 2674 01/22/82 AUTHOR EPA ADDRESSEE SCHOBER AE COPYEE DOCUMENT 2675 08/22/78 AUTHOR ADDRESSEE COPYEE BRAUN WH SMITH FA TYPE PAGES MARTIN JB M I L L I G A N DJ REPORT 25 ALEXANDER HC SCHOBER AE LETTER HAVEL J LANING ER SKURSKI MJ OSBORNE DW 2 REPORT 1 DOW MEMO FOOD DEPT CA DOW BISHOP F 1 LETTER 2 MOUNTFORT RF DOW REPORT DOW 1 i*fr'(L to CD <1 TITLE MCDONALD K TOMKE JA MERCER C WILSON JD PAGE 384 THE ACUTE TOXICITY OF 24D TO REPRESENTATIVE AQUATIC ORGANISMS (ES-584). MAYES MA GERSICH FM DOW MEETING REGARDING ESTERON 245BE QUALITY AND OPTIONS. DOW WOODS J TICHON JM EISCHER RL YTZEN GL ESTERON 245 BE HERBICIDE (DOW RANGELAND BRUSH KILLER T (XRM-4498) (Z45T BUTOXYETHYL ESTER, EMULSIFIABLE CONCENTRATE CONTAINING 4.0 LB. AE/TAL.) (DEVELOPMENTAL PRODUCT TRANSFER TO COMMERCIAL STATUS). EHRMANTRAUT JW WOOD CR SPECIAL LOCAL NEED REGISTRATIONS, ESTERON BRUSH KILLER, CA-780065, ESTERON 245 HERBICIDE, CA-780066. ESTERON 245 BE, EPA FILE SYMBOL 464-LTU, YOUR SUBMISSION OF NOVEMBER 9, 1981 (811109). TCDD TISSUE DISTRIBUTION AND EXCRETION FOLLOWING A SINGLE ORAL DOSE IN FEMALE GUINEA PIGS (CRI 791735HR8D REPORT HET K-66681-(37 )). HEFNER JG NOLAN RJ NUMBER DATE DOCUMENT 2676 00/00/66 AUTHOR BJORKLUND NE ADDRESSEE COPYEE DOCUMENT 2677 AUTHOR BAGE G ADDRESSEE COPYEE 00/00/73 DOCUMENT 2678 10/05/60 AUTHOR DON ADDRESSEE COPYEE DOW ELSHERE D HAMMER OH KAGY JF MCINTYRE HH TISDALE NL DOCUMENT 2679 02/09/78 AUTHOR CALHOUN LL ADDRESSEE COPYEE DOW FISHBECK W JOHNS D LEAVITT FC OLSON KJ RINZEMA L VOGEL A DOCUMENT 2680 06/18/70 TYPE REPORT ERNE K PAGES 28 REPORT CEKANOVA E 5 DISTRB 16 REPORT OLSON KJ BARRONS KC FALKENSTEIN WJ HART A KILIAN DJ PERKINS RP WRIGHT N REPORT DOW BLAIR EH GEHRING PJ KILIAN DJ MADRID E OLSON RD ROBINSON VB 2 LEGIS 8 AUTHOR DUBRIDGE LA ADDRESSEE HART P COPYEE HART PA US SENATE -t S'' CO 03 CO TITLE PAGE 385 TOXICOLOGICAL STUDIES OF PHENOXYACETIC HERBICIDES IN ANIMALS (ACTA VET SCAND, 7, 364-390). NATL VETERINARY INST SHE ROYAL VETERINAY COL SWED TERATOGENIC AND EMBRYOTOXIC EFFECTS OF THE HERBICIDES 24D AND 245T (ACTA PHARMACOL ET TOX 32, 408-416). KAROL1NSKA INSTITUTET SW LARSSON KS RESULTS OF RANGE FINDING TOXICOLOGICAL DATA ON M-1845 AND M-1847 AGRICULTURAL CHEMICAL FORMULATIONS OF THE POTASSIUM SALT OF SILVEX (T60.14-39291-1 T2.30-190-1). OYEN F BOUNDY HH GAY HH HYMAS TA LUCE EN SCOLES G COLBY RW GREENE LM JONES GD LYNN GE STENGER VA ACUTE TOXICITY AND CHLORACNE POTENTIAL OF TARS FROM THE 24D(HET K-2372-(18)). KEELER PA LOCKWOOD DD CAPUTO R HOLDER BB LANGNER RR MCCOLLISTER DD PINKERTON M SCHWETZ BA DEGESERO RA HUMBERT DK LANHAM JM MOOLENAAR RJ PRUITT ME TALCOTT TA STATEMENT OF DR. LEE A. DUBRIDGE SCIENCE ADVISOR TO THE PRESIDENT AND DIRECTOR, OFFICE OF SCIENCE AND TECHNOLOGY ACCOMPANIED BY DR. EDWARD J. BURGER JR, TECHNICAL ASSISTANT (EFFECTS OF 245T AND RELATED HERBICIDES ON MAN AND THE ENVIRONMENT). BICKWIT BURGER NUMBER DATE DOCUMENT 2681 0 2 /0 7 /7 0 AUTHOR * NEW YORKER ADDRESSEE* COPYEE* DOCUMENT 2682 0 0 /0 0 /8 1 AUTHOR* VAINIO H ADDRESSEE* COPYEEi DOCUMENT 2683 0 0 /0 0 /8 2 AUTHOR* SHIVERICK KT ADDRESSEE* COPYEE* DOCUMENT 2684 1 1 /0 0 /7 3 AUTHOR* DOW ROSE J9 ADDRESSEE* COPYEE* DOCUMENT 2685 0 3 /0 4 /8 2 AUTHOR* DOW ADDRESSEE* DOW COPYEE* GANTZ RL DOCUMENT 2686 0 0 /0 0 /0 0 AUTHOR* IMPERIAL ADDRESSEE* COPYEE* DOCUMENT 2687 1 2 /0 0 /6 6 AUTHOR* BYRD BC PA ELECTIC ADDRESSEE* COPYEE* TYPE PAGES REPORT 17 WHITESIDE T REPORT NICKELS J 14 NEWS REPORT MUTHER TF 7 REPORT GEHRING PJ 14 LETTER WOODS CD ROSS EM DOW LABEL 1 1 REPORT DOW 13 <r^ CO CT> CD TITLE PAGE 386 A REPORTER AT LARGE, DEFOLIATION(NEW YORKER)(EFFECTS OF 245T ON MAN AND THE ENVIRONMENT). PHENOXY ACID HERBICIDES CAUSE PEROXISOME PROLIFERATION IN CHINESE HAMSTERS (SCANDINAVIAN JOUR OF WORK & ENTIRON HEALTH). LINNAINMAA K INST OF OCCUPATIONAL HEA EFFECTS OF TCDD ON SERUM CONCENTRATIONS AND THE UTEROTROPHIC ACTION OF EXOGENOUS ESTRONE IN RAIS (TOX & APPLIED PHARMACOLOGY 65, 170-176). UNIV OF FL THE FATE OF 245T FOLLOWING ORAL ADMINISTRATION TO RATS AND DOGS (JOUR OF TOX AND APPLIED PHARMACOLOGY 26(3), 339-351). LENG ML PIPER WN ESTERON 245BE HERBICIDE. YTZEN GL 2 PLUS 2 BRUSH KILLER (EPA REG A6A-20A-A07). HELICOPTER APPLICATIONS OF EXPERIMENTAL FORMULATIONS CONTAINING TORDON FOR COMPARISON WITH TORDON 101 MIXTURE BRUSH KILLER (PA2.11) CTTL . LITTLE S NORTHEASTERN FOREST EXP NUMBER DOCUMENT 2688 AUTHOR* DOW ADDRESSEE* COPYEE* DATE 09/01/71 TYPE PAGES REPORT 7 JOHNSON JE DOCUMENT 2689 03/00/77 AUTHOR KIMBROUGH RD HEW ADDRESSEE* COPYEE* NEWS REPORT CARTER CD PHILLIPS PE 9 DOCUMENT 2690 10/00/54 REPORT 8 AUTHOR* ROHE VK ADDRESSEE* COPYE* HYMAS TA DOCUMENT 2691 09/00/73 NEWS REPORT AUTHOR* ENVIRON HEALTH PERSPECTI GUPTA BN NIH VOS JG ADDRESSEE* COPYEE* 5 DOCUMENT 2692 09/00/73 REPORT 8 AUTHOR* GUPTA BN ZINKL JG ADDRESSEE* COPYEE* DOCUMENT 2693 09/00/73 AUTHOR* DOW NORRIS JM ADDRESSEE* COPYEE* MOORE JA REPORT EMERSON JL ROWE VK 13 T' GO O TITLE PAGE 387 THE PUBLIC HEALTH IMPLICATIONS OF WIDESPREAD USE TO THE PHENOXY HERBICIDES AND PICLORAM (BIOSCIENCE 21(17), 899-905). EPIDEMIOLOGY AND PATHOLOGY OF A TCCD POISONING EPISODE (ARCHIVES OF ENVIRON HEALTH, 77-85). LIDDLE JA DIV OF HEALTH MO CLINE RE SUMMARY OF TOXICOLOGICAL INFORMATION ON 29D ABD 295T TYPE HERBICIDES AND AN EVALUATION OF THE HAZARDS TO LIVESTOCK ASSOCIATED WITH THEIR USE AMERICAN JNL VET RSCH XV(57)622-629, 1959. POSTNATAL EFFECTS OF MATERNAL EXPOSURE TO TCDD (ENVIRON HEALTH PERSPECTIVES 81-85). MOORE JA ZINKL JG NIEHS HEMATOLOGIC AND CLINICAL CHEMISTRY EFFECTS OF TCDD IN LABORATORY ANIMALS (ENVIRON HEALTH PERSPECTIVES 5, 111-118)(730900 CONFERENCE ON DIBENZODIOXINS AND DIBENZOFURANS SPONSORED BY NIEHS, RESEARCH TRIANGLE PARK NC). NIEHS VOS JG TOXICOLOGY OF CHLORINATED DIBENZO-P-DIOXINS (ENVIRONMENTAL HEALTH PERSPECTIVES 87-99M730900). GEHRING PJ GERBIG CG SCHWETZ BA SPARSCHU GL NUMBER DOCUMENT 2694 DATE 09/00/75 AUTHOR BRADY TP ADDRESSEE COPYEE DON DOCUMENT 2695 08/00/72 AUTHOR EPA ADDRESSEE* COPYEE* DOCUMENT 2696 11/00/72 AUTHOR* ELLINGTON CP JR ADDRESSEE* COPYEE DOCUMENT 2697 00/00/69 AUTHOR* ISENSEE AR WOOLSON EA ADDRESSEE* COPYEE* DOCUMENT 2698 AUTHOR* DON ADDRESSEE* COPYEE* 04/15/70 DOCUMENT 2699 AUTHOR* DOM ADDRESSEE* COPYEE* 06/22/65 DOCUMENT 2700 01/00/41 AUTHOR* ADAMS EM SPENCER HC ADDRESSEE* COPYEE* TYPE REPORT PAGES 5 BRIGGS PR LANGER HG REPORT 7 KIMBROUGH RD REPORT KEARNEY PC 3 REPORT KEARNEY PC 13 MEMO 2 TEST 6 REPORT DOW 4 TITLE PAGE 388 FORMATION OF DIBENZODIOXINS AND OTHER CONDENSATION PRODUCTS FROM CHLORINATED PHENOLS AND DERIVATIVES (ENVIRON HEALTH PERSPECTIVE, 3-7). TOXICITY OF CHLORINATED HYDROCARBONS AND RELATED COMPOUNDS(A REVIEW INCLUDING CHLORINATED DIBENZODIOXINS AND CHLORINATED DIBENZOFURANSHARCH ENVIRON HEALTH 25, 126-131). PERSISTENCE AND METABOLISM OF CHLORODIOXINS IN SOILS (ENVIRONMENTAL SCIENCE & TECH, 6(12), 1017-1019). USDA WOOLSON EA DECONTAMINATION OF PESTICIDES IN SOILS (RESIDUE REVIEWS 29MEFFECTS OF 245T ON MAN AND THE ENVIRONMENT, 38<-396). PLIMMER JR USDA LIST OF REFERENCES ON DEGRADATION OF PHENOXY HERBICIDES, INCLUDING 245T (EFFECTS OF 2A5T ON MAN AND THE ENVIRONMENT, 382-383). THE DETERMINATION OF TCDD IN 245T BY GAS LIQUID CHROMATOGRAPHY (EFFECTS OF 2A5T IN MAN AND THE ENVIRONMENT, 367-372). THE RESPONSE OF RABBIT SKIN TO COMPOUNDS REPORTED TO HAVE CAUSED ACNEFORM DERMATITIS (EFFECTS OF 2A5T ON MAN AND THE ENVIRONMENT, 362-365). IRISH DD ROWE VK NUMBER DOCUMENT 2701 DATE 04/15/70 TYPE LEGIS PAGES 45 AUTHOR* BICKHIT L HART PA US SENATE ADDRESSEE COPYEE DOCUMENT 2702 AUTHOR: DOW ADDRESSEE COPYEE 00/00/72 DOCUMENT 2703 AUTHOR: DOH ADDRESSEE COPYEE 06/23/71 DOCUMENT 2704 01/00/80 AUTHOR KNAKE EL ADDRESSEE COPYEE: DOCUMENT 2705 00/00/81 AUTHOR ERIKSSON M AXELSON 0 UNIV HOSPITAL LINKPING ADDRESSEE COPYEE DOCUMENT 2706 AUTHOR: DOH ADDRESSEE COPYEE' 00/00/00 BLAIR EH JOHNSON JE NEHS REPORT HILLIAMS CS 7 REPORT GEHRING PJ 18 NEHS HEEDS TODAY 1 NEHS 8 REPORT HARDELL L UNIV HOSPITAL LUND SWEDEN PRESENT 1 TITLE PAGE 389 STATEMENT OF DR JULIUS E JOHNSON, VICE PRESIDENT AND DIRECTOR OF RESEARCH, DOW ACCOMPANIED BY ETCHYL BLAIR, DIRECTOR OF DOW AG CHEM RES VK ROWE DIRECTOR OF THE DOW TOX LAB AND GEORGE LYNN, DIRECTOR OF GOVERNMENT REGULATORY RELATIONS OF DOW (EFFECTS OF 245T ON MAN AND THE ENVIRONMENT, 360-404). COMM ON COMMERCE DOW LYNN GE ROWE VK THE CURRENT STATUS OF PHENOXY HERBICIDES!IVM 4(1), 6-11). THE EFFECT OF 24D (24D) AND ESTERS OF 24D ON RAT EMBRYONAL, FOETAL AND NEONATAL GROWTH AND DEVELOPMENT (FD COSMET TOX 9, 801-817). SCHWETZ BA SPARSCHU GL THE BURIAL OF THE TWO MILLION DOLLAR TEASPOON, EDITORIAL (WEEDS TODAY). SOFT-TISSUE SARCOMAS AND EXPOSURE TO CHEMICAL SUBSTANCES, A CASE-REFERENT STUDY (BRITISH JOUR OF IND MEDICINE (38, 00-00). BERG NO UMEA SWEDEN MOLLER T SWEDEN UNIV HOSPITAL PRODUCT TORDON RTU, TORDON 101R FORESTRY HERBICIDE, TORDON 225E KURON, TORDON 10K PELLETS, GARLON, TORDON 2E. NUMBER DOCUMENT 2707 DATE 09/29/67 TYPE LETTER PAGES 1 AUTHOR* BEUTEL AP DOW ADDRESSEE* RENEGOTIATION BOARD USA SEMPLE PT COPYEE* DOCUMENT 2708 00/00/80 NEWS A REPORT AUTHOR* FANELLI R CASTELLI MG ISTITUTO DI RICHERCHE FA MARTELLI A ADDRESSEE* COPYEE* DOCUMENT 2709 09/00/73 NEWS 15 AUTHOR* MOORE JA ADDRESSEE* COPYEE* REPORT NIEHS DOCUMENT 2710 00/00/78 AUTHOR* HARDELL L ADDRESSEE* COPYEE* REPORT 22 SANDSTROM A DOCUMENT 2711 03/03/78 REPORT 12 AUTHOR* BAUGHMAN R ADDRESSEE* COPYEE* HARVARD DOCUMENT 2712 02/22/57 AUTHOR* DOW ADDRESSEE* CH BOEHRINGER SOHN COPYEE* DOW KNAPP ROWE VK LETTER 1 SMITH FB WEY B GRISWOLD AM KRAHN 0 VANDERWEELE JC O "v j -Ci co TITLE PAGE 390 APPLICATION FOR COMMERCIAL EXEMPTION FOR THE YEAR 660000 OF THE PHENOXY BASE WEED AND BRUSH KILLERS IN ACCORDANCE WITH THE PROVISIONS OF SECTION 106 OF THE RENEGOTIATION ACT OF 510000 (REFERENCE LPI 10581 12) CTTL. PRESENCE OF TCDD IN WILDLIFE LIVING NEAR SEVESO, ITALY A PRELIMINARY STUDY (BULLETIN OF ENVIRON CONTAMINATION 8 TOX 24, (460-463)). NOSEDA A GARATTINI S EFFECT OF TCDD ON THE IMMUNE SYSTEM OF LABORATORY ANIMALS (ENVIRON HEALTH PERSPECTIVES)(PRESENTED AT NIEHS CONFERENCE ON CHLORODIBENZO DIOXINS, RESEARCH, 730402 TO 730403). VOS JG ZINKL J CASE CONTROL STUDY SOFT TISSUE SARCOMAS AND EXPOSURE TO PHENOXYACETIC ACIDS OR CHLOROPHENOLS. UNIV HOSPITAL SWEDEN THE EVALUATION OF POSSIBLE HEALTH HAZARDS FROM TCDD IN THE ENVIRONMENT (PRESENTATION FOR SYMPOSIUM ON THE USE OF HERBICIDES IN FORESTRY ARLINGTON, VA 780221 TO 780222). MESELSON M OKEEFE P PREPARATION OF TRICHLOROPHENOL TO AVOID CHLORACNE. HOYLE H MELCHING WA KLEINE MYERS JR HUMBER DOCUMENT 2713 AUTHOR: DOM ADDRESSEE DOW COPYEE DOM DATE 07/28/75 DOCUMENT 2714 AUTHOR: DOW ADDRESSEE COPYEE 05/00/78 DOCUMENT 2715 05/20/61 AUTHOR: BAUER H ADDRESSEE COPYEE DOCUMENT 2716 12/26/74 AUTHOR DISHBURGER HJ ADDRESSEE* COPYEE* DISHBURGER HJ BJORK CK HEFNER RE LENG ML MOSS RD SEYMOUR KG WILLIAMS CS DOCUMENT 2717 07/19/78 AUTHOR* DOW MAHLE NH ADDRESSEE* COPYEE DOW DONALDS JE HANSON RG JANTZ OK MITCHELL MK PRUITT ME SPEER LH WILLIAMS CS DOCUMENT 2718 AUTHOR DOW ADDRESSEE COPYEE: 08/04/76 TYPE PAGES LETTER REPORT FRASER JM DAVIDSON JH HOFF RC 2 LABEL 1 REPORT SCHULTZ KH 23 REPORT DOW DOM COULTER LL HYMAS TA LINCE M NAEGELE RE SHAVER RJ 41 REPORT HUMMEL RA 20 BROOKENS RG FERGUSON RH HEBBOURN RG KENAGA EE MOSS RD SAUNDERS ES THEIS JM LEGIS SHADOFF LA 5 CO TITLE KURON BRUSH AND HEED KILLER, LOT MM 501048. PAGE 391 KURON. OCCUPATIONAL INTOXICATION OCCURRING IN THE PRODUCTION OF CHLOROPHENOL COMPOUNDS. SPIEGELBERG U RESIDUE STUDY; DISSIPATION OF SILVEX AND 245-TRICHL0R0PHEN0L IN TISSUES OF CATTLE FED SILVEX (R&D REPORT GH-C 7 7 4K 75 0052). JENSEN DJ MILLER PH BARRONS KC GETZENDANER ME KARHAL JH LYNN GE OSBORNE DH SHELDON HH BAURIEDEL HR HANSON RG KENAGA EE MCCOLLISTER DD PRUITT ME WATSON AJ A RESIDUE STUDY ON BEEF CATTLE CONSUMING TCDD JENSEN DJ KOCHER CW COULTER LL GORING CA HUNTER RC LENG ML MULLISON WR SEYMOUR KG VRANISH SR DISHBURGER HJ HAAGSMA TA HYMAS TA MCCOLLISTER DD OSBORNE DW SMITH LL WESELOH JW STATEMENT OF LEWIS A SHADOFF ON TCDD IN THE ENVIRON. SHADOFF LA NUMBER DOCUMENT 2719 DATE 07/00/75 AUTHOR THALKEN CE ADDRESSEE COPYEE DOCUMENT 2720 00/00/57 AUTHOR KIMMIG VJ ADDRESSEE COPYEE DOCUMENT 2721 00/00/77 AUTHOR: b l a u GE SAUERHOFF MH ADDRESSEE COPYEE DOCUMENT 2722 AUTHOR: DOW ADDRESSEE COPYEE 00/00/80 DOCUMENT 2723 AUTHOR DOW ADDRESSEE COPYEE 00/00/00 DOCUMENT 2724 00/00/79 AUTHOR CRUMMETT WB STEHL RH ADDRESSEE COPYEE 1 DOCUMENT 2725 00/00/74 AUTHOR AXELSON 0 ADDRESSEE COPYEE TYPE ABSTRACT REPORT USAF PAGES 42 NEHS REPORT SCHULZ KH 7 REPORT BRAUN WH 9 REPORT 17 SHADOFF LA LEGAL TALCOTT AT 6 REPORT DOW 43 NEWS REPORT SUNDELL L 8 TITLE PAGE 392 ABSENCE OF TCDD TOXICITY TO A RODENT POPULATION FOLLOWING MASSIVE FIELD APPLICATIONS OF 245T HERBICIDEU AM VET MED ASSOC 167, 861). WARD WE YOUNG AL BERUFLICHE AKNE (SOG CHLORAKNE) DURCH CHLORIERTE AROMATISCHE ZYKLISCHE THER (DERMATOLOGICA 115, 5A0). UNIV HAUTKLINIK HAMBURG THE FATE OF 24D FOLLOWING ORAL ADMINISTRATION TO MAN (TOXICOLOGY). DOW GEHRING PJ THE DETERMINATION OF TCDD IN HUMAN MILK. TESTIMONY OF AT TALCOTT SHOECRAFT ET AL VS DOW. A SEARCH FOR CHLORINATED DIOXINS IN THE ENVIRONMENT. HUMMEL RA SHADOFF LA HERBICIDE EXPOSURE MORTALITY AND TUMOR INCIDENCE AN EPIDEMIOLOGICAL INVESTIGATION ON SWEDISH RAILROAD WORKERS (WORK ENVIRONMENT AND HEALTH 11,21-28). YRKESMEDICINSKA KLINIKEN DOCUMfcn; I/2b AUTHOR: ADDRESSEE COPYEE uu/oo/oo DOCUMENT 2727 00/00/78 AUTHOR KATER L VOS JG ADDRESSEE COPYEE DOCUMENT 2728 00/00/77 AUTHOR HARDELL L ADDRESSEE* COPYEE DOCUMENT 2729 00/00/78 AUTHOR* DOW ADDRESSEE* COPYEE DOCUMENT 2730 01/06/79 AUTHOR* HARDELL L ADDRESSEE* COPYEE* DOCUMENT 2731 00/00/80 AUTHOR AXELSON ADDRESSEE* COPYEE DOCUMENT 2732 12/00/75 AUTHOR* FAITH RE THIGPEN JE ADDRESSEE* COPYEE KcPURT 19 MC LITY OF PERSuMS EXPOSED TO DIOXIN DURING AN ACCI r WHICH OC^KRED IN THE BASF AG ON 531117. REPORT 7 KREEFTENBERG JG IMMUNE SUPPRESSION BY TCDD (DIOXIN, TOXICOLOGICAL AND CHEMICAL ASPECTS, 163-175). NATL INST OF PUBLIC HEAL UNIVERSITY HOSPITAL NETH NEWS 2 MALIGNA MESENKYMALA TUMORER OCH EXPOSITION FOR FENOXISYROR, EN KLINIK OBSERVATION (LAKARTIDNINGEN 79(33), 2753-2759). REPORT REGIONAL HOSPITAL SWEDEN NEWS REPORT HUMMEL RA 8 THE DETERMINATION OF TCDD IN BIOLOGICAL EXTRACTS BY GAS CHROMATOGRAPHY MASS SPECTROMETRY (BIOMEDICAL MASS SPECTROMETRY 5(1), 7-13). SHADOFF LA NEWS 2 MALIGNANT LYMPHOMA OF HISTIOCYTIC TYPE AND EXPOSURE TO PHENOXYACETIC ACIDS OR CHLOROPHENOLS (THE LANCET, 55-56). REPORT UNIV HOSPITAL SWEDEN REPORT 19 ERIKSSON M MALIGNANT LYMPHOMA AND EXPOSURE TO CHEMICAL SUBSTANCES, ESPECIALLY ORGANIC SOLVENTS, CHLOROPHENOLS AND PHENOXY ACIDS (LAKARTIDNINGEN 77(9), 208-210). HARDELL L LENNER P REPORT 6 MCCONNELL EE INCREASED SUSCEPTIBILITY TO BACTERIAL INFECTION AS A SEQUELA OF EXPOSURE TO TCDD (INFECTION AND IMMUNITY 12(6), 1319-1329). MOORE JA NIEHS 05 P 1 NUMBER DOCUMENT 2733 DATE 04/17/70 AUTHOR CROW KD ADDRESSEE COPYEE DOCUMENT 2734 00/00/79 AUTHOR* BISANTI L FARA GM MONTESARCHIO E VOLPATO C ADDRESSEE* COPYEE* DOCUMENT 2735 00/00/77 AUTHOR* DOW ADDRESSEE* COPYEE* DOCUMENT 2736 05/06/80 AUTHOR* DOW SHADOFF LA ADDRESSEE* COPYEE* DOW GEHRING PJ VRANISH SR DOCUMENT 2737 00/00/79 AUTHOR* HARDELL L ADDRESSEE* COPYEE* DOCUMENT 2738 00/00/79 AUTHOR* HARDELL L ADDRESSEE* COPYEE* TYPE REPORT PAGES 21 PRINCESS MARGARET REPORT 33 BONETTI F FAVARETTI C PUCCINELLI V ZAMBRELLI E CALCS REPORT OTT MG 18 REPORT KNOLL FJ 13 COOK RR SCHWETZ BA REPORT 7 SANDSTROM A NEWS REPORT SANDSTROM A 7 TITLE PAGE 394 CHLORACNE, A CRITICAL REVIEW INCLUDING A COMPARISON OF TWO SERIES OF CASES OF ACNE FROM CHLORNAPHTHALENE AND PITCH FUMES (DOWLING ORATION DELIVERED AT ST THOMAS' HOSPITAL). HOSPIT EXPERIENCE OF THE ACCIDENT OF SEVESO (PROCEEDINGS OF THE 6TH ETS CONF 790904 TO 790907 HUNGARY). CARAMASCHI F DELCORNO G GIAMBELLUCA S MARNI E REGIONE LOMBARDIA ITALY REMOTTI G ANALYSIS OF SELECTED LABORATORY TESTS AMONG EMPLOYEES PRESUMABLY EXPOSED TO TCDD (EXAM PERIOD 640900 TO 650300). DETERMINATION OF DIOXINS HUMAN MILK SAMPLES FROM RESIDENTS OF WASHINGTON (ML AL 80-50246). LANGHORST ML LOOMIS T CRUMMETT WB SCRIVEN JG DAVIDSON JH VENABLE J CASE CONTROL STUDY SOFT TISSUE SARCOMAS AND EXPOSURE TO PHENOXYACETIC ACIDS OR CHLOROPHENOLS (BR JOUR CANCER 790000 39, 711). UNIV HOSPITAL UMEA SWEDE CASE CONTROL STUDY SOFT TISSUE SARCOMAS AND EXPOSURE TO PHENOXYACETIC ACIDS OR CHLOROPHENOLS!BR J CANCER 39, 711-717). UNIV HOSPITAL SWEDEN NUMBER DOCUMENT 2739 DATE 00/00/80 AUTHOR: ANDERSSON K KLING H ADDRESSEE COPYEE: DOCUMENT 27A0 ` 00/00/79 AUTHOR MONSANTO ADDRESSEE COPYEE: DOCUMENT 27Al 00/00/73 AUTHOR FISHER P ADDRESSEE COPYEE-' DOCUMENT 27A2 01/11/78 TYPE NEWS PAGES 7 REPORT AXELSON 0 SUNDELl L 1 REPORT SUSKIND RR 19 NEWS REPORT TUNG TT 30 REPORT 17 AUTHOR: ASP S RIIHIMAKI V ADDRESSEE COPYEE: GEPPAIAINEN AM DOCUMENT 27A3 00/00/79 NEWS 20 REPORT AUTHOR AXELSON A BERG NO LITERATURE RESEARCH MLLER T ADDRESSEE: COPYEE: DOCUMENT 27AA 01/11/78 REPORT 1A AUTHOR AXELSON 0 ADDRESSEE: COPYEE: REGIONAL HOSPITAL 4378 TITLE PAGE 395 HERBICIDE EXPOSURE AND TUMOR MORTALITY CAN UPDATED EPIDEMIOLOGIC INVESTIGATION ON SWEDISH RAILROAD WORKERS)(SCAND J WORK ENVIRON HEALTH 6(1980) 73-79). EDLING C HOGSTEDT C THE MORTALITY EXPERIENCE OF WORKERS EXPOSED TO TETRACHLORODIBENZODIOXIN IN A TRICHLOROPHENOL PROCESS ACCIDENT. UNIV OF CINCINNATI MEDIC ZACK JA PRIMARY CANCER OF THE LIVER IN VIETNAM (CHIRURGIE 99(7), A27-A36). COORDINATION OF EPIDEMIOLOGICAL STUDIES ON THE LONG TERM HAZARDS OF CHLORINATED DIBENZODIOXINS AND CHLORINATED DIBENZOFURANS (SYMPTOMATOLOGY MORBIDITY AND MORTALITY EXPERIENCE OF CHLORINATED PHENOXYACID HERBICIDE 24D 2A5T SPRAYERS IN FINLANDHA CLINICAL AND EPIDEMIOLOGICAL STUDY). HERNBERG S INST OF OCCUPATIONAL HEA CASE CONTROL STUDY ON MALIGNANT MESENCHYMAL TUMORS OF THE SOFT PARTS AND EXPOSURE TO CHEMICAL SUBSTANCES (LAKARTIDNINGEN 76, 3872-3875). ERIKSSON M SWEDEN HARDELL L A REVIEW ON SWEDISH EPIDEMIOLOGICAL STUDIES WITH RELATIONS TO CHLORINATED DIBENZODIOXINESfWORKING PAPER TO THE IARC MEETING 780110 TO 780111 ON COORDINATION OF EPIDEMIOLOGIC STUDIES ON THE LONG TERM HAZARDS OF CHLORINATED DIBENZODIOXINES AND CHLORINATED DIBENZOFURANES). SWEDEN NUMBER DOCUMENT 27*45 DATE 00/00/79 TYPE REPORT PAGES 3 AUTHOR HOGSTEDT C HOGSTADT C ADDRESSEE COPYEE HESTERLUND B DOCUMENT 2746 09/00/76 AUTHOR GOLDMANN P ADDRESSEE* COPYEE* REPORT THEISS AM 5 DOCUMENT 2747 00/00/73 AUTHOR GOLDMAN PJ ADDRESSEE* COPYEE DOCUMENT 2748 09/00/77 REPORT 9 LITERATURE RES REPORT 11 AUTHOR NATL BD OF HEALTH AND ME ADDRESSEE* COPYEE* DOCUMENT 2749 AUTHOR* ADDRESSEE* COPYEE* 00/00/00 MEDREC 1 DOCUMENT 2750 11/14/78 REPORT 4 AUTHOR COOK RR ADDRESSEE COPYEE DOCUMENT 2751 AUTHOR* BASF ADDRESSEE* COPYEE* 00/00/00 DOM REPORT 13 FRENTZELBEYME R TITLE PAGE 396 COHORT STUDY OF DEATH CAUSES AMONG TIMBER WORKERS WITH AND WITHOUT EXPOSURE TO PHENOXY ACID PREPARATIONSCEPA TRANSLATION) (SELECTED PAPERS ON 295T AND TCDD). WESTERLUND B LITERATURE RES FOLLOW UP REPORT ON THE TRICHLOROPHENOL-DIOXIN ACCIDENT AT BASF AG ON 531113(EPA TRANSLATION)(SELECTED PAPERS ON 2A5T AND TCDD). LITERATURE RES SEVERE ACUTE CHLORACNE, A MASS INTOXICATION BY 2367-TETRACHL0R0DIBENZ0DI0XIN(SELECTED PAPERS ON 2A5T AND TCDD). CONGENITAL MALFORMATIONS AND PERINATAL DEATH IN A SWEDISH COUNTY, A STUDY OF THE RELATION TO EXPOSURE TO 245T (REPORT FROM THE SWEDISH NATIONAL BOARD OF HEALTH AND WELFARE). KAUKO SATAMA LABORATORY TEST RESULTS (SHOEMAKER VS DOW). REVIEW OF THE TRANSLATED ARTICLE HARDELL L AND SANDSTROM A CASE-CONTROL STUDY MALIGNANT MESENCHYME SOFT TISSUE TUMOUR AND EXPOSE TO PHENOXY ACIDS OR CHLOROPHENOLS (LAKARTIDNINGEN 75N40) 780000) . MORTALITY STUDY OF PERSONS EXPOSED TO DIOXIN AFTER AN ACCIDENT WHICH OCCURED IN THE BASF ON 531113. THIESS AM NUMBER DATE TYPE PAGES DOCUMENT 2752 01/00/72 REPORT 7 AUTHOR AUS DER RZTLICHEN ABTEI GOLDMAN PJ ADDRESSEE* COPYEE* DOCUMENT 2753 01/30/79 REPORT AUTHOR* CHETOCK JJ GREAVES RD U. S. FOREST SERVICE ADDRESSEE* COPYEE* 65 DOCUMENT 275A 00/00/79 AUTHOR* ANDERSON K KLING H ADDRESSEE* COPYEE* ABSTRACT REPORT AXELSON 0 SUNDELL L 17 DOCUMENT 2755 02/00/70 AUTHOR* BINNS W HEGGESTAD HE SAND PF ADDRESSEE* COPYEE* REPORT 31 CUETO C HEPTING GH STEPHENSi RF DOCUMENT 2756 00/00/71 REPORT 12 AUTHOR* ARCH ENVIRON HEALTH SMITH D ADDRESSEE* COPYEE* METTER G DOCUMENT 2757 11/10/76 AUTHOR* DAVIDSON JH ADDRESSEE* DOW MINTZ MJ SCHWETZ BA COPYEE* LETTER REPORT DOW CRUMMETT MB MUELDER WW SEWARD WB 2 CO GO 6'' O TITLE PAGE 397 SCHWERSTE AKUTE CHLORAKNE DURCH TRICHLORPHENOLZERSETZUNGSPROPUKTE CARBEITSMEDZIN SOZIALMEDIZIN ARBEITSHYGIENE 7C1), 12-18). FORESTRY RELATED IMPACTS OF 245T IN OR. KNAPP WH OR ST DEPT OF FORESTRY HERBICIDE EXPOSURE AND TUMOR MORTALITY AN UPDATED EPIDEMIOLOGICAL INVESTIGATION ON SWEDISH RAILROAD WORKERS. EDLING C UNIV HOSPITAL SWEDEN HOGSTEDT C INVESTIGATION OF SPRAY PROJECT NEAR GLOBE, AZ. ELIASON BC FREEMAN B MI ST UNIV PIMENTEL D TSCHIRLEY FH A HEALTH SURVEY OF WORKERS IN 2AD AND 2A5T PLANT WITH SPECIAL ATTENTION TO CHLORACNE, PORPHYRIA CUTANEA TARDA, AND PSYCHOLOGIC PARAMETERS (ARCH ENVIRON HEALTH 22, 316-327). POLAND AP POSSICK P CHLORINATED DIOXIN ISSUE MANAGEMENT TEAM MEETING 761117. HOLDER BB OLSON RD JOHNSON RL PARSEY ES NUMBER DATE DOCUMENT 2758 11/19/80 AUTHOR ROSS RT ADDRESSEE COPYEE USDA ARNOLD 8 PORTER EPA LAUTERBACH AA PATTON D VERTAC WHELAN E DOCUMENT 2759 AUTHOR* DOW ADDRESSEE* DOW COPYEE* DOW 07/28/75 DOCUMENT 2760 07/00/74 AUTHOR* AGEE JL ADDRESSEE* COLLEAGUE COPYEE DOCUMENT 2761 AUTHOR* DOW ADDRESSEE* COPYEE* 03/11/65 DOCUMENT 2762 02/05/68 AUTHOR* SCOTT RA JR ADDRESSEE* COPYEE* DOCUMENT 2763 AUTHOR* ADDRESSEE* COPYEE* 00/00/00 DOCUMENT 2764 10/24/78 AUTHOR* THORNTON PL ADDRESSEE* AREA DIRECTORS COPYEE* TYPE PAGES TITLE PAGE 398 LEGIS USDA 3A DIRECT TESTIMONY OF DR RALPH T ROSSIIN RE DOH ET AL)(REFERENCE 15)(WERNER H BRAUN EXHIBITS AND REFERENCES). AM CNCL ON SCIENCE 8 HEA AM FARM BUR FEDN BREINHOLT MM BUTLER WA GILLHAM M JACKSON TG MAYFIELD CD NFPA PRICE WR JR RADEMACHER JJ WARREN JM WENKER JA ZACKRISON JA ANDERSON S ENVIRON DEFENSE FUND KIRK RS JR NW COALTN ALT PEST STEVENS JE JR WERTHEIMER RJ LETTER FRASER JM DAVIDSON JH HOFF RC 1 KURON BRUSH AND WEED KILLER, LOT NO MM 501048. LETTER REPORT EPA 82 DIOXIN IMPLEMENTATION PLAN. REPORT SILVERSTEIN L EARLY DOW HISTORY OF THE CHLORACNE PROBLEM(BIOCHEM'S CONTRIBUTION) CTTL. ABSTRACT 2 CORPS OF ENGINEERS NEW AQUATIC PLANT CONTROL PROGRAM (ABSTRACTS 680000 MEETING OF WSSA NEW ORLEANS LA 680205 TO 680208). US CORP OF ENGINEERS MEMO 1 ACTIVE SERVICE LIST FOR RISKS. REPORT USDA FS DUBBELS W PESTICIDE USE COORDINATING COMMITTEE ADVISORY MEMORANDUM 206. REGIONAL FORESTERS STATION DIRECTORS -4 CO - 4 QO NUMBER DOCUMENT 2765 DATE 12/05/80 TYPE REPORT PAGES 18 AUTHOR HOPES CONSULTINO ADDRESSEE COPYEE DOCUMENT 2766 10/27/80 AUTHOR HARDY TS ADDRESSEE EPA COPYEE EPA ARNOLD 8 PORTER GILLHAM M LAUTERBACH AA PATTON D USDA WERTHEIMER RJ DOCUMENT 2767 05/13/63 AUTHOR DOW ADDRESSEE DOWNARD GM COPYEE DOCUMENT 2768 06/26/63 AUTHOR DOWNARD GM ADDRESSEE DOW COPYEE DOCUMENT 2769 AUTHOR DOW ADDRESSEE COPYEE 01/12/78 DOCUMENT 2770 11/10/64 AUTHOR DOW ADDRESSEE DOWNARD GM COPYEE DOW MCILNAY CQ LEGIS 53 REGGIANI 0 AM CNCL SCI & HEALTH BREINHOLT MM JACKSON TO MAYFIELD CD PRICE WR JR VERTAC WHELAN EM LETTER MCINTYRE HH USDA 1 LETTER USDA MCINTYRE HH 1 REPORT SHADOFF LA 6 LETTER SACHS SB USDA HAMMER OH 1 CO 00 to TITLE PAGE 399 AN INVESTIGATION OF THE POSSIBLE EFFECTS OF PESTICIDE EXPOSURES ON REPRODUCTIVE MORTALITY AND MORBIDITY, PART 1 PRELIMINARY REPORT COMPARISONS BETWEEN POPULATIONS OF AGRICULTURAL PILOTS AND THEIR SIBLINGS MHO ARE NOT OCCUPATIONALLY EXPOSED TO PESTICIDES (REPORT SUBMITTED TO NATL AG AVIATION ASSN, FOR RELEASE ON 801203). ROAN CC DIRECT TESTIMONY OF DR G REGGIANI(EXHIBIT 861)(D0W, ET AL.). AM FARM BUR FEDERATION BUTLER HA KIRK RS JR NFPA RADEMACHER JJ WARREN JM ANDERSON S ENVIRON DEFENSE FUND LATHROP KOONTZ RIGHTER C NW COALTN ALT PEST STEVENS JE JR WENKER JA OUELLETTE FE REVISED LABEL FOR KURON BRUSH KILLER REGISTRATION 969-162 HITH LETTER OF 630515. STATEMENT OF LEWIS A SHADOFF FOR THE COMMITTEE OF ENVIRONMENTAL PROTECTION ASSEMBLY BILL 1093. ESTERON 76BE REG 969-279. DOWFUME W-85 REG 969-121. DOW GENERAL WEE KILLER REG 969-098. KURON REG 969-162. VERTIFUME REG 966-188. SUNDERLAND WW NUMBER DATE TYPE PAGES DOCUMENT 2771 00/00/79 REPORT 41 AUTHOR: GIVAUDAN RES CENTER SAMBETH J ADDRESSEE COPYEE HOFFMANN LAROCHE WIPF HK DOCUMENT 2772 AUTHOR: DOW ADDRESSEE COPYEE 00/00/00 LABEL 3 DOCUMENT 2773 03/06/72 REPORT AUTHOR: AZ COMUNITY PEST STUDIES MORGAN DP ADDRESSEE COPYEE 7 DOCUMENT 2774 12/23/64 AUTHOR: DOWNARD GM ADDRESSEE DOW COPYEE LETTER USDA SACHS SB 1 DOCUMENT 2775 AUTHOR DOW ADDRESSEE COPYEE 10/00/69 LABEL 2 DOCUMENT 2776 AUTHOR DOW ADDRESSEE COPYEE 07/00/72 REPORT LENG ML 9 DOCUMENT 2777 AUTHOR: REA JM ADDRESSEE DOW COPYEE 11/04/70 LETTER USDA 1 DOCUMENT 2778 06/25/78 REPORT 22 AUTHOR DAVIDSON JH ADDRESSEE COPYEE: DOW DESAI P GEHRING PJ HOLDER BB CO LAFOLLETTE QO CO DOW AM FARM BUR ASSN DISHBURGER HJ GREFRATH B JOHNS D LAWRENCE B TITLE PAGE 400 THE SEVESO ACCIDENT; ITS NATURE, EXTENT AND CONSEQUENCES!AN OCCUP HYG VOL22 3273-70). HOMBERGER E REGGIANI G KURON BRUSH KILLER. ALLEGED EFFECTS ON HUMAN HEALTH OF THE USE OF HERBICIDES IN THE AREA AROUND GLOBE AZ. ROAN CC KURON BRUSH KILLER REGISTRATION 464-162 HITH LETTER OF 641110. KURON LOW VOLATILE WEED AND BRUSH KILLER. RESIDUES IN MILK AND MEAT AND SAFETY TO LIVESTOCK FROM THE USE OF PHENOXY HERBICIDE IN PASTURE AND RANGELAND (DTE 28(1), 12-20). KURON BRUSH KILLER USDA REG 464-162 YOUR APPLICATION OF 700717. THE ESTIMATION OF THE TCDD TOXIC POTENTIAL IN THE LIGHT OF THE SEVESO ACCIDENT (PRESENTED 20TH CONGRESS OF THE EUROPEAN SOCIETY OF TOXICOLOGY BERLIN 780625 TO 780628). F HOFFMANN LA ROCHE 8 CO REGGIANI G BLAIR EH DOST F HEALY M JOHNSON SR LENG ML DAY B DOWNS T HEBBOURN R KOCIBA RJ MAIN RE NUMBER DATE MCCOLLISTER DD MOSS RD OR ST UNIV SCHROETER RH TRAYNOR MJ WALSTAD J YOUNG AL DOCUMENT 2779 AUTHOR: DOW ADDRESSEE COPYEE: 04/11/60 DOCUMENT 2780 AUTHOR* DOW ADDRESSEE COPYEE 02/19/60 DOCUMENT 2781 00/00/00 AUTHOR: BLAU GE ADDRESSEE COPYEE: DOCUMENT 2782 05/31/60 AUTHOR: LA ST UNIV ADDRESSEE DOW COPYEE* DOCUMENT 2783 00/00/72 AUTHOR GOLDMAN PJ ADDRESSEE* COPYEE* DOCUMENT 2784 AUTHOR* DOW ADDRESSEE USDA COPYEE* DOW 06/15/60 TYPE PAGES MELVIN W NEWTON M ROSS WURM ASSOC SCHWETZ BA TSCHIRLEY FH WITT J REPORT 1 REPORT 8 REPORT DOW 154 LETTER STAMPER ER SOUTHWICK L 1 REPORT 27 RALPH MCELROY CO LETTER MCINTYRE HH WHITE RO LYNN GE 1 4 CO C* 00 TITLE MI ST UNIV NORRIS LA ROWE VK SMITH LL USAF WULF M MILLER G NORRIS MG SCHARNWEBER C THOMPSON T VRANISH SR WURM R KURON USE RECOMMENDATION IN SUGAR CANE. PAGE 401 A RESIDUE STUDY OF KURON IN SUGAR CANE. PHARMACOKINETIC STUDIES IN EVALUATION OF THE TOXICOLOGICAL AND ENVIRONMENTAL HAZARD OF CHEMICALS. GEHRING PJ WATANABE PG CRITICALLY ACUTE CHLORACNE CAUSED BY TRICHLOROPHENOL DECOMPOSITION PRODUCTS (ARBEITSMEDIZIN SOZIALMEDIZIN ARBEITSHYGIENE 7(1), 12-18 720000). RECOMMENDATIONS FOR USE OF KURON CTTL. OUELLETTE FE SOUTHWICK L WIFFEN EE NUMBER DATE DOCUMENT 2785 03/29/65 AUTHOR ' DON ADDRESSEES ROWE VK COPYEEs AMSTUTZ FC FALSEY WP GRANT LB HOLDER BB LYNN GE PLETCHER DE STAEHLING EC DOCUMENT 2786 AUTHOR- DOW ADDRESSEE COPYEEs 00/00/00 DOCUMENT 2787 02/10/64 AUTHOR BAKER G I OHH ADDRESSEE COPYEEs DOCUMENT 2788 02/27/64 AUTHOR: DOW ADDRESSEES DOWNARD GM COPYEEs DOW DOCUMENT 2789 AUTHOR! DOW ADDRESSEE COPYEEs 00/00/69 DOCUMENT 2790 AUTHOR DOW ADDRESSEE COPYEEs 11/00/00 DOCUMENT 2791 03/02/65 AUTHORS DOW ADDRESSEE COPYEEs BARRONS KC TYPE PAGES REPORT 6 SILVERSTEIN LG BARRONS KC FEINAUER HH HANSEN KY HOYLE HR MCCOY WJ RILEY FH TUCKER JC LABEL 4 MEMO DAVIS H LYNN GE 1 LETTER SACHS SB USDA HAMMER OH MEMO 1 3 LABEL 2 MINUTES LYNN GE CORBIN WL 2 CO QO or TITLE REPORT ON THE CHLORACNE PROBLEM MEETING ON 650324 CORBIN HL GILL HH HARRIS JH HUTCHENREUTHER CO OTIS CE SADEK SE WILTSE MG DOEDENS JD GILL HM HOFF RC IRISH DD PETERSON JE SMILEY RN KURON BRUSH KILLER. PAGE 402 LABEL COPY FOR KURON BRUSH KILLER. DOH HOLDEMAN GE SACHS SB HOLF MA KURON REGISTRATION 464-162. SUNDERLAND HH CHRONOLOGY OF CHLORACNE TESTING IN BRL. KURON BRUSH KILLER. MINUTES OF "EXCITER" PROBLEM MEETING, 650204, DISPOSITION OF THE MONSANTO 245T CTTL. HOYLE HR NUMBER DATE DOCUMENT 2792 04/09/64 AUTHOR DOWNARD GM ADDRESSEES DOW COPYEEs TYPE PAGES LETTER 1 USDA MCINTYRE HH DOCUMENT 2793 AUTHORS DOM ADDRESSEES COPYEEs 12/30/64 LABEL 3 SOUTHWICK L DOCUMENT 2794 AUTHORS DOW ADDRESSEES DOW COPYEEs 07/30/64 LETTER REPORT HOLMES R HOYLE HR 3 DOCUMENT 2795 AUTHORS DOW ADDRESSEES DOW COPYEEs DOW 12/10/64 LETTER SOUTHWICK L HAMMER OH LICHY CT 2 DOCUMENT 2796 03/02/65 AUTHOR DEPT OF HEALTH MI ADDRESSEES DOW COPYEEs LETTER 1 SCOVILL RG SILVERSTEIN LG DOCUMENT 2797 12/15/64 AUTHORS DOW SACHS SB ADDRESSEE COPYEE' MEMO HAMMER OH 1 DOCUMENT 2798 06/24/65 AUTHOR: DOW ADDRESSEE DOW COPYEEs DOW G0ER6EN G SILVERSTEIN L LETTER ROWE VK MULHOLLAND R ROWE VK HOLDEMAN G 2 DOCUMENT 2799 12/23/64 AUTHOR! AG EXP STATION FL ADDRESSEE COPYEE LETTER ORSENIGO JR 1 v0 C0O0 CF) TITLE PAGE 403 AMENDED LABEL FOR KURON BRUSH KILLER REGISTRATION 464-16Z RECEIVED ON 640302. KURON BRUSH KILLER. MANUFACTURE OF TRICHLOROPHENOL AT 199 BLDG. KURON FOR FL SUGARCANE. LYNN GE WILTSE MG PRECAUTIONS INSTITUTED TO MINIMIZE TRICHLOROPHENOL "CONTAMINANT" EXPOSURE CTTL. LABEL COPY FOR KURON BRUSH KILLER. HOLDEMAN GE LYNN GE 245-TRICHL0R0PHEN0L, THE T ACIDS, AND ASSOCIATED ACNEGENS. AMSTUTZ FC HOYLE H FALSEY N OTIS C UNIV OF FL NUMBER DOCUMENT 2800 AUTHOR: DON ADDRESSEE* COPYEE* DOW DATE 05/04/65 TYPE PAGES LETTER 2 WHITE LC JR DOSSER RC DOCUMENT 2801 05/04/65 AUTHOR* DOW ADDRESSEE* DOW SCULATI, JJ COPYEE* LETTER 2 HOFF RC AMSTUTZ FC SILVERSTcIN LG DOCUMENT 2802 AUTHOR* DOW ADDRESSEE* COPYEE* 05/04/65 LABEL 4 DOCUMENT 2803 04/28/65 AUTHOR* DEPT OF HEALTH MI ADDRESSEE* DOW COPYEE* LETTER 1 SCOVILL RG SILVERSTEIN L DOCUMENT 2804 07/14/65 AUTHOR* DOW ADDRESSEE* SACHS SB COPYEE* LETTER DOWNARD GW 4 DOCUMENT 2805 03/01/65 AUTHOR* DOEDENS JD ADDRESSEE* COPYEE* DOW REPORT DOW ROWE VK DOCUMENT 2806 AUTHOR* DOW ADDRESSEE* COPYEE* 11/24/65 LABEL DOCUMENT 2807 02/18/65 AUTHOR* DOEDENS JD ADDRESSEE* DOW COPYEE* DOW HUTCHENREUTHER C J* CO ^ 00 .<1 LETTER DOW RILEY FH FEINAUER HW OTIS CE TITLE 245T ACID PRODUCT SPECIFICATION. SMITH HA 245-TRICHLOROPHENOL AND 245T ANALYSIS FOR TCDD. BAILEY CZ STAEHLING EC GILL HH WHITE LC KURON BRUSH KILLER. PAGE 404 C SUGGESTION OF UV LIGHT TO DETERMINE PRESENCE OF CONTAMINANT IN TRICHLOROPHENOL PRODUCTION AREA CTTL. KURON BRUSH KILLER REGISTRATION 464-162 WITH LETTER OF 650601. USDA TRICHLOROPHENOL SUMMARY. KURON BRUSH KILLER. 245-TRICHLOROPHENOL. SMILEY RN GRANT LB SILVERSTEIN L TUCKER JC HARRIS JW STAEHLING EC NUMBER DATE DOCUMENT 2808 12/02/65 AUTHOR: DOMNARD GM ADDRESSEE: DOM COPYEE TYPE LETTER USDA SACHS SB PAGES 1 DOCUMENT 2809 07/11/66 AUTHOR: DOM MATSON AJ ADDRESSEE: COPYEE* LABEL MEMO I OHH 2 DOCUMENT 2810 AUTHOR: DOM ADDRESSEE* DOM COPYEE* DOM 11/23/65 CHART 6 LETTER TEST GETZENDANER ME GOMELL GE LYNN GE DOCUMENT 2811 07/08/66 LETTER AUTHOR* AM SUGAR CANE LEAGUE LAUDEN LL ADDRESSEE* DOM HAMMER OH COPYEE* AG EX SERVICE LA LA ST UNIV STAMPER ER USDA 2 DOCUMENT 2812 AUTHOR* DOM ADDRESSEE* COPYEE* 11/00/65 LABEL 2 DOCUMENT 2813 10/05/66 AUTHOR* DOMNARD GM ADDRESSEE* SUNDERLAND MM COPYEE* LETTER USDA 1 DOCUMENT 2819 AUTHOR* DOM ADDRESSEE* COPYEE* 10/17/73 LABEL 6 DOCUMENT 2815 AUTHOR* USDA ADDRESSEE* DOM COPYEE* 10/17/73 LEGAL HOERGER FJ 2 CO 00 00 TITLE I ..JE DOW HURON BRUSH KILLER REG 464-162 WITH LETTER OF 651102. 405 LABEL COPY FOR HURON SUGAR CANE USERS. LYNN GE SACHS SB SUGAR CANE JUICE FROM HURON TREATMENTS. SOUTHWICK L LOUPE D HURON BRUSH KILLER. MILLHOLLON R USE OF SUGARCANE DOW HURON BRUSH KILLER REGISTRATION 464-162 WITH LETTER OF 660808. WEED CONTROL IN SUGARCANE IN LA. TANK MIX RECOMMENDATIONS. PROPOSED LABELING. HURON. APPLICATION FOR AMENDED REGISTRATION OF ECONOMIC POISONS. NUMBER DOCUMENT 2816 AUTHOR* DOW ADDRESSEE* COPYEE* DATE 08/00/66 DOCUMENT 2817 AUTHOR* DOW ADDRESSEE* COPYEE* 06/00/67 DOCUMENT 2818 AUTHOR* ADDRESSEE* DOW COPYEE* 07/20/66 DOCUMENT 2819 AUTHOR* DOW ADDRESSEE* COPYEE* 08/00/67 DOCUMENT 2820 10/00/68 AUTHOR* DOW ADDRESSEE* COPYEE* MCINTYRE: HH DOCUMENT 2821 09/01/71 TYPE LABEL PAGES 3 LABEL 3 AUTH ROWE VK LABEL 1 3 LABEL 3 REPORT 7 AUTHOR* DOW ADDRESSEE* COPYEE* DOCUMENT 2822 09/00/69 AUTHOR* DOW ADDRESSEE* COPYEE* MCINTYRE HH DOCUMENT 2823 AUTHOR: DOW ADDRESSEE* COPYEE* AJJ 12/00/70 JOHNSON JE LABEL LABEL 3 1 CO 00 CO TITLE KURON WEED AND BRUSH KILLER (12107-010-1) PAGE 406 KURON WEED AND BRUSH KILLER (12107-010-2). CONTINUING RESEARCH ON CHLORACNE USING HUMAN SUBJECTS. KURON WEED AND BRUSH KILLER (1207-010-2). KURON WEED AND BRUSH KILLER (1207-010-3). THE PUBLIC HEALTH IMPLICATIONS OF WIDESPREAD USE OF THE PHENOXY HERBICIDES AND PICLORAM(BIOSCIENCE 21(17), 899-905) (PRESENTED AT THE SYMPOSIUM ON POSSIBLE PUBLIC HEALTH IMPLICATIONS OF WIDESPREAD USE OF HERBICIDES, AM INST OF BIOLOGICAL SCIENCES, BLOOMINGTON, IN 700826). KURON LOW - VOLATILE WEED AND BRUSH KILLER (1207-010-4). KURON LOW - VOLATILE WEED AND BRUSH KILLER. NUMBER DATE DOCUMENT 2824 00/00/78 AUTHOR: BETSO JE ADDRESSEE COPYEE DOCUMENT 2825 09/00/71 AUTHOR: DOM ADDRESSEE COPYEE MCINTRYRE HH DOCUMENT 2826 00/00/79 AUTHOR KITCHIN KT ADDRESSEE COPYEE DOCUMENT 2827 AUTHOR DOW ADDRESSEE COPYEE: 09/00/73 DOCUMENT 2828 00/00/77 AUTHOR FAITH RE ADDRESSEE COPYEE DOCUMENT 2829 AUTHOR: DOW ADDRESSEE COPYEE: 05/00/74 DOCUMENT 2830 00/00/79 AUTHOR: HINSDILL RD ADDRESSEE: COPYEE TYPE REPORT DOW LABEL PAGES 7 1 REPORT NIEHS LABEL 10 2 NEWS REPORT MOORE JA 14 LABEL 2 NEWS REPORT THOMAS PT 22 " ' CO CO . TITLE PAGE 407 PHENOXY ACIDS. EFFECTS AND FATE IN MAMMALS (CHLORINATED PHENOXY ACIDS AND THEIR DIOXINS ECOL BULL (ST0CKH0LM)27, 122-133). GEHRING PJ KURON LOW - VOLATILE WEED AND BRUSH KILLER (1207-010-6). TCDD EFFECTS ON HEPATIC MICROSOMAL CYTOCHROME P-448-MEDIATED ENZYME ACTIVITIES (TOX AND APPLIED PHARMACOLOGY 47, 537-546). WOODS JS KURON LOW - VOLATILE BRUSH AND WEED HERBICIDE (SPECIFICATION 101586-021-6). IMPAIRMENT OF THYMUS DEPENDENT IMMUNE FUNCTIONS BY EXPOSURE OF THE DEVELOPING IMMUNE SYSTEM TO TCDD (JOUR OF TOX AND ENVIRON HEALTH 3, 451-464). NIEHS KURON LOW - VOLATILE BRUSH AND WEED HERBICIDE (SPECIFICATION 12107-010-8). THE EFFECT OF PERINATAL EXPOSURE TO TETRACHLORODIBENZO-P-DIOXIN ON THE IMMUNE RESPONSE OF YOUNG MICE (DRUG AND CHEM TOX 2(182), 77-98). UNIV OF MI NUMBER DATE DOCUMENT 2831 00/00/00 AUTHOR FAITH RE ADDRESSEE* COPYEE* DOCUMENT 2832 05/00/77 AUTHOR* NIEHS ADDRESSEE* COPYEE* DOCUMENT 2833 03/24/59 AUTHOR* LA AO EXP STA ADDRESSEE* COPYEE* DOCUMENT 2834 00/00/74 AUTHOR* MOORE JA ADDRESSEE* COPYEE* DOCUMENT 2835 00/00/78 TYPE PAGES REPORT 16 LUSTER MI NEWS REPORT VOS JO 4 REPORT 24 STAMPER ER NEWS 22 REPORT NATL INST OF ENVIRON NEWS 28 AUTHOR* HOFFMAN LAROCHE ADDRESSEE* COPYEE* DOCUMENT 2836 00/00/79 AUTHOR* BEYER JE KEYES DG ADDRESSEE* COPYEE* REPORT REGGIANI G NEWS REPORT CARREON RM KOCIBA RJ 5 CO <x> TITLE PAGE 408 INVESTIGATIONS ON THE EFFECTS OF TCDD ON PARAMETERS OF VARIOUS IMMUNE FUNCTIONS. NIEHS ORAL ROBERTS UNIV IMMUNE SUPPRESSION AS RELATED TO TOXICOLOGY (CRITICAL REVIEWA IN ROX 5, 67-101). CHEMICAL WEED CONTROL REPORT OF THE DEPT OF PLANT PATHOLOGY LA AG EXP STATION, BATON ROUGE, LA, TO THE CONTACT COMMITTEE OF THE AM SUGARCANE LEAGUE FOR THE YEAR 1958. SUPPRESSION OF CELLULAR IMMUNITY IN RATS AND MICE BY MATERNAL TREATMENT WITH TCDD (INT ARCH ALLERGY 47, 777-794). HEA NIH VOS JG MEDICAL PROBLEMS RAISED BY THE TCDD CONTAMINATION IN SEVESO, ITALY (REVIEW ARTICLE)!ARCH. TOX. 40, 161-188MPRESENTED AT THE 5TH INTERNATIONAL CONFERENCE ON OCCUPATIONAL HEALTH IN THE CHEMICAL INDUSTRY (MEDICHEM) SAN FRANCISCO, CA, 770905 TO 770910). LONG TERM TOXICOLOGIC STUDIES OF TCDD IN LABORATORY ANIMALS (ANNALS NEW YORK ACADEMY OF SCIENCES PART 5 CARCINOGENICITY 397-404). DOW GEHRING PJ NUMBER DOCUMENT 2837 DATE 03/12/57 TYPE REPORT PAGES 12 AUTHOR* CHILTON SJ ADDRESSEE* COPYEE* STAMPER ER LA AG EXP STA DOCUMENT 2838 02/15/59 AUTHOR* LA AG EXP STA ADDRESSEE* COPYEE* CHILTON SJ REPORT STAMPER ER DOCUMENT 2839 00/00/80 REPORT 17 AUTHOR* ERIKSSON M ADDRESSEE* COPYEE* HARDELL L DOCUMENT 2840 00/00/77 REPORT 15 AUTHOR* BRAUN WH ADDRESSEE* COPYEE* DON DOCUMENT 2841 12/00/55 AUTHOR * EXPERMNT STAT HSPA ADDRESSEE* COPYEE* BRYANT CA HANSON NS PENDERGAST DT REPORT 8 EXPRMT STA HSPA COULTER LL KAGY JF SMITH HL DOCUMENT 2842 AUTHOR* DOW ADDRESSEE* COPYEE* 01/00/60 REPORT 56 DOCUMENT 2843 09/26/76 REPORT AUTHOR* CENTER FOR BIO NATURAL S COMMONER B ADDRESSEE* COPYEE* 30 CO CD ro TITLE PAGE WEED CONTROL REPORT OF THE DEPT OF PLANT PATHOLOGY LA AG EPS STATION, BATON ROUGE, LA, TO THE CONTACT COMMITTEE OF THE AM SUGARCANE LEAGUE FOR THE YEAR 1956. $09 RECOMMENDATIONS FOR JOHNSON GRASS SEEDLING AND JOHNSON GRASS CONTROL IN SUGARCANE. MALIGNANT LYMPHOMA AND EXPOSURE TO CHEMICAL SUBSTANCES ESPECIALLY TO ORGANIC SOLVENTS, CHLOROPHENOLS AND PHENOXY ACIDS (A CASE CONTROL STUDY) (LAKARTIONINGEN 77($) 208-210) UMEA DOSE DEPENDENT PHARMACOKINETIC PROFILE OF SILVEX FOLLOWING INTRAVENOUS ADMINISTRATION IN RATSUOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 2, 605-618). LEBEAU JE SAUERHOFF MW COMPARISON OF SILVEX AND DCMU WITH OTHER COMMONLY-USED HERBICIDES FOR PRE-EMERGENCE WEED CONTROL (SPECIAL RELEASE 13$). FITZGERALD CD LYNN GE SOUTHWICK L FLETCHER FW OTIS CE KURON IN SUGAR CANE - PERFORMANCE DATA AND USE RECOMMENDATIONS. ACCIDENTAL CONTAMINATION OF SOIL WITH DIOXIN IN MISSOURI EFFECTS AND COUNTERMEASURES. SCOTT RE NUMBER DOCUMENT 2844 AUTHOR DOM ADDRESSEE* COPYEE* DATE 06/00/67 TYPE LABEL / PAGES 1 DOCUMENT 2845 AUTHOR DOM ADDRESSEE* COPYEE* 02/00/69 LABEL 1 DOCUMENT 2846 00/00/79 REPORT 7 AUTHOR F HOFFMANN LAROCHE SMITZ REGGIANI G ADDRESSEE COPYEE DOCUMENT 2847 AUTHOR DOM ADDRESSEE COPYEE 05/00/69 LABEL 2 DOCUMENT 2848 AUTHOR DOM ADDRESSEE COPYEE 07/00/67 LABEL 1 DOCUMENT 2849 06/00/70 AUTHOR BEAN J ADDRESSEE HORTON J COPYEE REPORT 1 DOCUMENT 2850 02/00/70 AUTHOR BINNS M HEGGESTAD HE STEPHENS RF ADDRESSEE COPYEE REPORT CUETO C HEPTING GH 32 DOCUMENT 2851 08/04/71 AUTHOR* AZ ADDRESSEE* HAND EL COPYEE* REPORT SMART RM TX 6 0 CO CO CO TITLE ESTERON 99 CONCENTRATE PAGE A10 ESTERON 99 CONCENTRATE. ESTIMATION OF THE TCDD TOXIC POTENTIAL IN THE LIGHT OF THE SEVESO ACCIDENT (MECHANISM OF TOXIC ACTION ON SOME TARGET ORGANS, ARCH TOXICOL, SUPPL 2, 291-302). KURON HEED AND BRUSH KILLER. VEON 2A5. KURON. INVESTIGATION OF SPRAY PROJECT NEAR GLOBE, AZ (INVESTIGATION CONDUCTED 700200). ELIASON BC FREEMAN B PIMENTEL D SAND PF EXHIBIT E KURON COMPLAINTS NUMBER DATE DOCUMENT 2532 03/00/58 AUTHOR EXPRMT STA HSPA ADDRESSEE COPYEE ANDERSON F DOCUMENT 2533 00/00/00 AUTHOR ALLEN JR VANMILLER JP ADDRESSEE COPYEE* DOCUMENT 2539 00/00/00 AUTHOR BERRY DL SLAGA TJ ADDRESSEE COPYEE DOCUMENT 2535 00/00/00 AUTHOR HOLMES PA SHEFNER AM ADDRESSEE COPYEE DOCUMENT 2536 00/00/00 AUTHOR BEYER JE KEYES DG ADDRESSEE COPYEE DOCUMENT 2537 00/00/72 AUTHOR HUNTER JH ADDRESSEE* # COPYEE* DOCUMENT 2538 00/00/76 AUTHOR ARNOLDS EL ADDRESSEE COPYEE* TYPE PAGES REPORT 9 HANSON NS BIRON RA ABSTRACT BARSOTTI DA 1 ABSTRACT 1 DIGIOVANNI J UNIV WA ABSTRACT 1 IIT RES INST AND ABSTRACT CARREON RM KOCIBA RJ 1 ABSTRACT USAF 1 ABSTRACT USAF 1 CO CO TITLE PAGE 365 COMPARISON OF SIMAZIN AND OTHER NEWER HERBICIDES FOR PRE-EMERGENCE WEED CONTROL (SPECIAL RELEASE 165). SMITH HL SOUTHWICK L REPRODUCTIVE EFFECTS OF HALOGENATED AROMATIC HYDROCARBONS ON NONHUMAN PRIMATES. LAMBRECHT LK UNIV HI STUDIES WITH CHLORINATED DIBENZO-P-DIOXINS, POLYBROMINATED BIPHENYLS AND POLYCHLORINATED BIPHENYLS IN A TWO STATE SYSTEM OF MOUSE SKIN TUMORIGENESIS POTENT ANTI CARCINOGENIC EFFECTS. JUCHAU MR OAK RIDGE NATL LAB LONG TERM EFFECTS OF TCDD AND HCDD IN MICE AND RATS. UNIV CH RICHTER WR RUST JH LONG TERM TOXICOLOGIC STUDIES OF TCDD IN LABORATORY ANIMALS. DOW GEHRING PJ CHEMICAL ANALYSIS FOR DIOXIN AND DEFOLIANT RESIDUES IN SOIL FROM TEST AREA C-52A EGLIN AFB, FL. WOOLSON EA YOUNG AL FIELD STUDIES OF THE SOIL PERSISTENCE AND MOVEMENT OF 2AD, 2A5T AND TCDDCPRESENTATION TO WSSA ABSTRACT NO 206). WACHINSKI AM YOUNG AL NUMBER DOCUMENT 2539 AUTHOR USAF ADDRESSEE COPYEE DATE 00/00/74 DOCUMENT 2540 09/00/73 AUTHOR BENEZET HT ADDRESSEE COPYEE DOCUMENT 2541 00/00/72 AUTHOR ELLINGTON CP JR ADDRESSEE* COPYEE DOCUMENT 2542 00/00/76 AUTHOR UNIV OF NI ADDRESSEE COPYEE* DOCUMENT 2543 00/00/76 AUTHOR GARCIA JD ADDRESSEE COPYEE* DOCUMENT 2544 10/25/79 AUTHOR* AGRESTI A OR ST UNIV USDA ADDRESSEE* COPYEE DOCUMENT 2545 05/04/73 AUTHOR ALLEN JR ADDRESSEE* COPYEE* TYPE ABSTRACT YOUNG AL PAGES 1 ABSTRACT MATSUMURA F 1 ABSTRACT KEARNEY PC 1 ABSTRACT WARD CT 1 ABSTRACT GONTANEK B 1 REPORT HIGGINS JE ORTIZ M JR WAGNER SL 119 NEWS 14 REPORT CARSTENS LA A. ^ CO CO C J\ TITLE PAGE 366 ECOLOGICAL STUDIES ON A HERBICIDE EQUIPMENT TEST AREA (NATL TECH INFORM. SERV, 140)(ABSTRACT 76-0357). STUDIES ON THE BIOACCUMULATION AND MICROBIAL DEGRADATION OF TCDD (ENVIRON HEALTH PERSPECTIVES S, 253-258). PERSISTENCE AND METABOLISM OF CHLORODIOXINS IN SOILS (ENVIRON SCI TECH 6(12), 1017-1019). WOOLSON EA STUDIES ON THE DEGRADATION OF TCDD IN LAKE HATER AND SEDIMENTS. TX TECH UNIV NOXIOUS BRUSH AND WEED CONTROL RESEARCH HIGHLIGHTS VOL 7. HARRIS B RHODES MJ A SCIENTIFIC CRITIQUE OF THE EPA ALSEA II STUDY AND REPORT WITH THE 791116 SUPPLEMENT. NM ST UNIV NORRIS LA UNIV OF FL UNIV OF SC WITT JM LIGHT AND ELECTRON MICROSCOPIC OBSERVATIONS IN MACACA MULATTA MONKEYS FED TOXIC FAT (AM JOUR VET RES 28(126, 1513-1526). UNIV OF WI NUMBER DOCUMENT 2546 AUTHOR * DON ADDRESSEE COPYEE DATE 00/00/61 DOCUMENT 2547 AUTHOR DOW ADDRESSEE COPYEE 00/00/60 DOCUMENT 254S AUTHOR DOW ADDRESSEE COPYEE 00/00/73 DOCUMENT 2549 AUTHOR DOW ADDRESSEE COPYEE 00/00/00 DOCUMENT 2550 AUTHOR DOW ADDRESSEE COPYEE 04/00/59 DOCUMENT 2551 00/00/72 AUTHOR BUUHOI NP SAINTRUF 0 ADDRESSEE COPYEE DOCUMENT 2552 AUTHOR WHO ADDRESSEE COPYEE 02/07/83 TYPE PAGES PRESENT 6 WILTSE MO PRESENT WILTSE M6 6 REPORT 8 SOUTHWICK LS REPORT LICHY CT 4 REPORT 2 NEWS 2 REPORT CHANH PH CENTRE NATIONAL REPORT 47 'CbM CD CD 05 TITLE PAGE 367 AQUATIC VEGETATION CONTROL IN RECREATIONAL AREAS (ACD FILE HA-26)(PRESENTED AT THE 1961 MI FORESTRY AND PARK ASSN ANNUAL CONF). AQUATIC VEGETATION CONTROL WITH KURON (ACD FILE HA-23)(PRESENTED AT 1960 MEETING OF THE WEED SOCIETY OF AM). KURON SILVEX HERBICIDE CONTINUES TO GAIN ACCEPTANCE (DOWN TO EARTH 28(4)26-32, 1973). PROGRAM YOUR AQUATIC WEED CONTROL NEEDS. END TO WATER WEEDS KURON OFFERS A CONTROL FOR UNWANTED VEGETATION IN LAKES AND PONDS (DOW DIAMOND, APRIL 1959). ORGANS AS TARGETS OF "DIOXIN" CTCDD) INTOXICATION (JG HEFT 4, 174-175). SESQUE G LA RE AZUMGELADE MC MRS ENVIRONMENTAL HEALTH CRITERIA 24D. NUMBER DATE DOCUMENT 2553 02/15/80 AUTHOR * LENG ML ADDRESSEE* DAVIDSON JH NORRIS MG CASTILLO L COPYEE* TYPE PAGES MEMO 1 DOW FISCHER AC THEIS JM TUCKER MD DOCUMENT 2554 - 08/05/81 AUTHOR* WEED JM ADDRESSEE* HEITZIG W COPYEE* CALDWELL B DOWNS L REPORT LEE B 1 DOCUMENT 2555 05/18/82 AUTHOR* EPA ADDRESSEE* SCHOBER AE COPYEE* LETTER 1y MOUNTFORT RF DOW DOCUMENT 2556 05/19/82 AUTHOR* SCHOBER AE ADDRESSEE* DOW COPYEE* GLEDHILL GR CONYERS ES MEMO DOW BUZZELLI D LANINO ER 1 DOCUMENT 2557 09/00/81 NEWS 7 REPORT AUTHOR* EPA HRYHORCZUK DO POLLUTION CONTROL BD IL HESSE CS ADDRESSEE* COPYEE* DOCUMENT 2558 02/06/81 AUTHOR* SANDERSON CA ADDRESSEE* COPYEE* NEWS ROGERS LJ 3 DOCUMENT 2559 AUTHOR* ADDRESSEE* COPYEE* % 02/12/81 NEWS 1 b b h -g J CD -a TITLE PAGE 368 LABELS FOR ESTERON 245, ESTEROH BRUSH KILLER AMD KURON APPROVED CTTL. FREDERICK DM WATSON AJ WOODS CD MULLISON WR WESELOH JW WINE LM ESTERON 245 ROBINSON, ILLINOIS. ZWEIGLE R SHAFER G TCDD ANALYSES ESTERON 245BE EPA REGISTRATION 464-574 FOLLOWUP TO OUR REGISTRATION NOTICE OF MARCH 29, 1982 C820329). ESTERON 245BE, TCDD ANALYSIS. GOODMAN CH WOODWARD RE A WIRE RECLAMATION INCINERATOR AS A SOURCE OF ENVIRONMENTAL CONTAMINATION WITH TCDD & TETRACHLORODIBENZOFURANS CARCHIVES OF ENVIRON HEALTH 36(5), 228-234). UNIV OF IL BEASLEY VR WITHROW WA 245T CAUSES BEHAVIORAL EFFECTS IN CHICKENS AT ENVIRONMENTALLY RELEVANT DOSES. HERBICIDE IS REAL-RISK TO BIRDS 8 PEOPLE NUMBER DATE DOCUMENT 2560 03/12/82 AUTHOR: LEN6 ML ADDRESSEE* COPYEE DOCUMENT 2561 03/00/83 AUTHOR* VET ADMIN ADDRESSEE* COPYEE* DOCUMENT 2562 06/25/83 AUTHOR* SCHMIDT B ADDRESSEE* COPYEE DOCUMENT 2563 AUTHOR* DOW ADDRESSEE* COPYEE* 03/11/82 DOCUMENT 2564 00/00/00 AUTHOR* HUMMEL RA DOM ADDRESSEE* COPYEE* DOCUMENT 2565 AUTHOR* ADDRESSEE* COPYEE* 00/00/00 DOCUMENT 2566 AUTHOR* ADDRESSEE* F DICK COPYEE* 09/30/83 DOCUMENT 2567 10/26/83 AUTHOR* COOK RR ADDRESSEE* WHEATER RH COPYEE* MAY VT TYPE NEWS DOM PAGES 2 REPORT HOBSON LB 21 MEMO TELECON 1 LABEL 4 CHART TEST JENSEN DJ 11 REPORT 10 MEMO 2 LETTER 1 DOM AM MEDICAL ASSN VOSTAL TITLE JUMPING CHICKENS; RELEVANCE TO HAZARD IN HUMANS. ROGERS LJ SANDERSON CA PAGE 369 EPIDEMIOLOGY OF SOFT-TISSUE SARCOMA RELATED HUMAN RESEARCH AS RELATED TO HERBICIDE EXPOSURE. ALLEGED COMPLAINT ON SPRAYING ESTERON 2A5 CTTL. ESTERON 245BE. THE GAS CHROMATOGRAPHIC-MASS SPECTOMETRIC DETERMINATION OF TCDD IN FAT FROM CATTLE FED RONNEL INSECTICIDE. MAHLE NH SHADOFF LA TOXICOLOGICAL EVIDENCE OF A HEALTH HAZARD. DON OFFICAL CORRESPONDENCE CONCERNING AM MEDICAL ASSN ADVISORY PANEL CTTL. DOH CORRESPONDENCE NITH AN MEDICAL ASSN OFFICIAL CONCERNING DIOXIN SYMPOSIUM IN AUSTRIA CTTL. GENERAL MOTORS RES LAB NUMBER DOCUMENT 2568 AUTHOR ADDRESSEE COPYEE* DATE 11/02/83 DOCUMENT 2569 02/03/82 AUTHOR SCHOBER AE ADDRESSEE EPA COPYEE LANING ER FAIRBAIRN D DOCUMENT 2570 03/02/82 AUTHOR SCHOBER AE ADDRESSEE EPA COPYEE LANING ER GOODMAN CH DOCUMENT 2571 02/03/82 AUTHOR EPA ADDRESSEE SCHOBER AE COPYEE DOCUMENT 2572 03/03/82 AUTHOR EPA ADDRESSEE SCHOBER AE COPYEE DOCUMENT 2573 03/19/82 AUTHOR DOW ADDRESSEE SCHOBER AE COPYEE DOCUMENT 257A 03/18/82 AUTHOR SCHOBER AE ADDRESSEE COPYEE DOCUMENT 2575 03/29/82 AUTHOR EPA ADDRESSEE SCHOBER AE COPYEE TYPE ABSTRACT PAGES 2 LETTER DOM MOUNTFORT R GOODMAN C ROSS E 1 LETTER DOW AKERMAN EPA ROSS ER 1 LETTER MOUNTFORT RF DOM 1 LETTER ADAMCZYK TE DOM 1 MEMO BUZZELI D DOM 1 LEGIS DOM 1 LETTER 1 MOUNTFORT RF DOM CO CO CO TITLE COMMENTS ON ANIMAL TOXICITY SEGMENT OF AMA DOCUMENT. PAGE 370 ESTERON 245BE. EPA FILE SYMBOL 464-LTU. YOUR LETTER OF JANUARY 13* 1982 (820113). YTZEN GL ARNOLD S ESTERON 245BE. EPA FILE SYMBOL 464-LTU. GRAY EC YTZEN GL CONYERS ES ESTERON 245 BE. EPA FILE SYMBOL 464-LTU. RESUBMISSION FEBRUARY 3, 1982 (820203). ESTERON 245 BE. EPA FILE SYMBOL 464-LTU. RESUBMISSION, MARCH 3, 1982 (820303). ESTERON 245 BE-TCDD ANALYSIS. CONFIDENTAL STATEMENT OF FORMULA. ESTERON 245 BE HERBICIDE. EPA MOUNTFORT RF TCDD ANALYSES, ESTERON 245 BE. EPA REGISTRATION 464-574. FOLLOW UP TO OUR REGISTRATION NOTICE OF MARCH 29, 1982 (820329). 4400 'V 'VVt * f* f ol -- pp ^ (o 0 3 5^ p rf 2- -5 SOUTH OKANAGAN ENVIRONMENTAL COALITION We believe that only through the preservation of a vital and diverse environment can human beings hope to survive on this planet. By understanding our role in the complex ecosystems which we inhabit, we can learn to live in harmony with all other species over the mil lennia. Our purpose is to educate people as to the need for careful examination of our activities, to see that they will not damage our environment and to take action where necessary to ensure the integrity of our ecosystems. For additional copies of "The Other Face of 2,4-D; A Citizens' Report," send $7.00 to: South Okanagan Environmental Coalition P.0. Box 188, Penticton, B. C. V2A 6K3 The South Okanagan Environmental Coalition is a non profit, voluntary organization. The price of this report only covers costs already incurred, plus mailing. We would greatly appreciate contributions to further our efforts to protect the environment of the Okanagan Basin lake system. -4 1 0 I as i 'i DOW CHEMICAL LATIN AMERICA August 3, 1982 ANALYTICAL METHOD R.O. BOX 340400 CORAL GABLES. HORIOA 33134 U/S.A. LA-AMC-82-001 QA Number 1961 ESTERON* 245 C Herbicide This is a file copy. For O utside Distribution Obtain Copies W ith lia b ility Clause 1. Scope and W ithout Dow Reference. ^ X This method is applicable to the analysis of ESTERON* 245 C Herbicide. A procedure Is given for the determination of the active ingredient as the acid equivalent. The concentrations of the butyl ester of 2,4,5-tr1chlorophenoxyacetlc acid (2,4,5-T) 1s calculated from the acid equivalent concentrations. Calculations are given for the pounds of 2,4,5-T per gallon and grams of 2,4,5-T per liter. The inert ingredients a w c V- C t * |J calculated by difference. 11 : <" 2 ' U t S 2 2. Safety Precautions M IDLM D ZICM 2.1 ESTERON 245 C must be handled with care. It 1s capable of causing skin and eye irritation or possibly a mild burn. Avoid skin and eye contact. Wear safety glasses and gloves. If contact occurs, wash affected area with plenty of water. For eye contact, see a physician. 2.2 Acetonitrile 1s a flammable and toxic solvent. Do not breathe its vapors. Work only 1n a well-ventilated area away from any source of ignition. Avoid skin and eye contact. 2.3 2-Propanol is a flammable solvent. Work only In a well-ventilated area away from any source of ignition. 2.4 Phosphoric acid is a corrosive acid. Wear chemical workers' goggles and impervious gloves to prevent skin and eye contact. 2.5 Sodium hydroxide 1s a corrosive base. Wear chemical workers' goggles and Impervious gloves to prevent skin and eye contact. 2.6 Good laboratory practices dictate that each analyst should be thoroughly acquainted with potential hazards of the reagents, products, and solvents before commencing laboratory work. For Information on the product being analyzed, consult the current Dow Material Safety Data Sheet supplied to Dow customers. Safety Information on reagents may be obtained from the supplier. Disposal of reagents, reactants, and solvents must be 1n compliance with local, state, and federal laws and regulations. fitW i l l 1261 Trademark of The Dow Chemical Company AN OPERATING UNIT OF THE DOW CHEMICAL COMPANY p - H fo 'l 008210 August 3, 1982 2 of 8 pages LA-AMC-82-001 3. Acid Equivalent 3.1 Principle The sample is saponified and the sample components together with an Internal standard are analyzed by liquid chromatography with an ultra violet absorption detector. Peak height measurement 1s used and the 2,4,5-T acid 1s quantitated by comparison to a standard of known purity. 3.2 Apparatus a) UV Detector: LDC Model 1203 with 280 nm conversion kit, available from Laboratory Data Control Company, 5000 Park Street, St. Petersburg, FL 33733, or equivalent. b) Pump: Milton Roy Instrument, M1ni-Pump Model 2396, available from Milton Roy Company, 5000 Park Street, St. Petersburg, FL 33733. c) Pressure Gauge: 0>5000 ps1g, Cat.' No. 9220 of Alltech Associates, available from the Anspec Company Inc., P.0. Box 7044, Ann Arbor, MI 48107. d) Sample Injection Valve: Rheodyne Model 70-10 with 10 ul sample loop, available from Alltech Associates Inc., 202 Campus Drive, Arlington Heights, IL 60004. e) Syringes: 100 u l , available from Hamilton Company, P.0. Box 10030, Reno, NV 89510, or equivalent. f) Recorder: Linear Model 155, available from Alltech Associates Inc., or equivalent. ro ro N g) Pre-Column: 4.6 mm I.D. x 50 mm stainless steel packed with.Whatman Co: Pell ODS, available from Whatman Inc., 9 Bridewell Place, Clifton, NJ, or equivalent. h) Column: 4.6 mm I.D. x 250 mm Partlsll 10-25 ODS, available from Whatman Inc. 1) Flow-through Bourdon tube: 1/4 Inch O.D. x 8 feet 316 stainless steel tubing, partially flattened and coiled. Available from Alltech Associates Inc., or equivalent. j) Reducing unions: 1/4 Inch to 1/16 Inch, available from Whatman Inc., or equivalent. ' k) Integrator: Hewlett-Packard 3380A, available from Hewlett-Packard, Route 41, Avondale, PA 19311, or equivalent. 3.3 Reagent 4609 a) Acetonitrile (non-spectro): distilled-ln-alass grade, Burdick and Jackson Laboratories, Inc., Muskegon, MI 49442, or equivalent.______ _ 0008211 M t FOR OUTSIDE 3 - H lo i DISTRIBUTION J August 3, 1982 3 of 8 pages LA-AMC-82-001 b) Hater, urn filtered, deionized. c) Phosphoric acid: 86%, ACS reagent grade, available from J. T. Baker Chemical Company, Phillipsburg, NJ 08865, or equivalent. d) Sodium hydroxide solution: 50%, ACS reagent grade, available from J. T. Baker Chemical Company, or equivalent. e) Eluent: To a 1-11 ter volumetric flask, add 200 ml acetonitrile, 600 ml of filtered deionized water, 34.2 g of 861 phosphoric acid, 18 g of 501 sodium hydroxide, and shake to dissolve. Add more water to the l-11ter mark and shake. Adjust pH to 2.95 0.05 using 50% sodium hydroxide or 86% phosphoric acid. Degas eluent prior to use. CAUTION: Do NOT add concentrated phosphoric acid and 50% sodium hydroxide together. Add each to the acetonltrile/water mixture separately. f) 2,4,5-Trlchlorophenoxyacetic Acid Analytical Standard: available from the Sample Coordinator, Agricultural Products Dept., P.0. Box 1706, Midland, MI 48640, U.S.A. Store 1n a desiccator over drying reagent. g) p-Bromophenol: available from Eastman Kodak Company, Rochester, NY 14650. h) 2-Propanol: ACS reagent grade, available from J.T. Baker Chemical Company, or equivalent. 1) Internal Standard Solution. Dissolve 13 g of potassium hydroxide and 4 g of p-bromophenol *1n one liter of 2:1 v/v (2-propanol:water). 3.4 Chromatographic Conditions -- r* o> o 3.41 Pre-Column: 4.6 mm ID x 50 mm, packed with Whatman Co: Pell ODS. (Note 3.94). Analytical Column: 4.6 mm ID x 250 mm Whatman Partlsil 10-25 ODS (Note 3.94). Eluent: 200 ml acetonitrile per liter of aqueous 0.3 M sodium dihydrogen phosphate-phosphoric acid buffer at pH 2.95. (Note 3.93). Flow rate: 2.67 ml/min. (Milton-Roy pump). Dtection: LDC Model 1203 at 280 nm. 0.512 absorbance unlts fui1 scale. Injection Volume: 10 ul (Rheodyne valve). 3.42 Typical Integration Parameters for the Hewlett-Packard 3380A .. S 55 T 5 O start delay: stop timer: area reject: slope sensitivity: attenuation: 1 minute 60 minutes 100 1.00 mV/nrinute 16 0008212 A August 3, 1982 4 of 8 pages LA-AMC-82-001 DOM 211 I 2 6 4 3.5 Calibration 3.51 Weigh about 70 mg of 2,4,5-T acid analytical standard to the nearest 0.1 mg Into a 10 dram vial. Pipet 25 ml of internal standard solution (Note 3.91). Shake to dissolve. 3.52 Analyze a 10-ul aliquot of the calibration standard prepared in 3.51 under the conditions listed in section 3.4 (Note 3.92). 3.53 Calculate the response factors (R.F.) for 2,4,5-T as follows (Note 3.95): a) R.F. A x 0 x P B' r C T I O T Where A B r~> C T\ 0 0P peak area for Internal standard, grams p-bromophenol/25 ml internal standard solution In calibration standard, peak area of the analytical standard, grams of analytical standard 1n the calibration standard. percent purity of the analytical standard. - 3 . 6 Procedure ^ 3 . 6 1 Weigh about 0.29 g of E5TER0N 245 C Herbicide Into a 10-dram vial. "=P1pet 25 ml of Internal standard solution (Note 3.91). Shake to dissolve. 3.62 Analyze a 10-ul aliquot of the sample solution under the conditions listed in Section 3.4. 3.7 Calculations 3.71 Calculate the percent 2,4,5-T for the sample as follows: nrsE x R.F. x H x 100 % 2,4,5-T acid equivalent Where E F G H R.F peak area of the 2,4,5-T peak for the sample solution. grams of sample. peak area of Internal standard. grams p-bromophenol/25 ml Internal standard solution. response factor. 3.8 Precision The data obtained by this procedure Indicate a relative standard devi ation of 1.02% for a sample containing 44.7% 2,4,5-T. The values obtained may be expected to vary from the average by -not more than 2.03% relative (2 sigma relative) at the 95% confidence level. 4611 I W* ei*'i> \ . ^ Z l !>:37R3,.jTGi4 j ^ 0 0 8 2 1 i. ----- :---------- H ' H f o l S August 3, 1982 5 of 8 pages LA-AMC-82-001 3.9 Notes 3.91 The use of a bulk Internal standard 1s convenient. However, valid results are Insured only when all standards and samples are prepared at the same time using the same Internal standard solution and the same plpet. 3.92 The calibration standard solution should be replaced with a freshly made solution after one month. 3.93 The fluent can be recirculated for 100 Injections. The eluent reservoir must be stirred continuously while it Is recycled. 3.94 Repack the Inlet of a fresh pre-column and/or analytical column with Whatman Co: Pell 00S after four days' use and thereafter if the chromatographic peaks tail. Replace the pre-column Inlet filter when the pressure gauge reads 3,500 psig or greater. 3.95 Best precision will be obtained 1f the column temperature is held constant. R.F. changes by about IS per 1C. . 4. Percent 2,4,5-Trlchlorophenoxyacetlc Acid Butyl Ester % 2,4-,5-T butyl ester (% 2,4,5-T acid) x 312 it- 1 5 5 where 256 * molecular weight of 2,4,5-trlchlorophenoxyacetlc acid 312 * molecular weight of 2,4,5-trlchlorophenoxyacetlc acid butyl ester 5. Pounds of 2,4,5-Tr1chlorophenoxyacet1c Acid Equivalent per U.S. Gallon 5.1 Principle The pounds of 2,4,5-T acid equivalent per gallon of ESTERON 245 C Herbicide are calculated from the percent acid equivalent, the specific gravity of the sample and the weight per gallon of water at 25C. A procedure 1s given for the determination of the specific gravity. 5.2 Procedure The specific gravity 1n air 1s determined by weighing a known volume of the sample 1n a pycnometer at 25C. The procedure used Is Method C of ASTM Designation D 891-59 except for one modification. The water bath 1s set at 25C. rs> 09 cn distribution 4612 0008214 August 3, 1982 6 of 8 pages LA-AMC-82-001 5.3 Calculation A x B x C pounds of 2,4,5-T acid equivalent per U.S. gallon where A X 2,4,5-T acid equivalent from 3.7 B * weight per gallon of water at 25C, which 1s 8.32 pounds per gallon C specific gravity of the sample as determined 1n 5.2 89*I I il H00 6. Grams of 2,4,5-T Acid Equivalent Per Liter E x 119.83 grams of 2,4,5-T acid equivalent per liter where E * pounds of 2,4,5-T acid equivalent per U.S. gallon calculated 1n Section 5.3 c;; 119.83 conversion factor from pound/gallon (U.S.) to grams/liter tm 7. Percent Inert Ingredients X Inerts 100% - (X 2,4,5-T butyl ester from Section 4) o*; ' l l 8. Literature References American Society for Testing and Materials, 1916 Race Street, Philadelphia, PA 19103, ASTM Designation 0 891-59, "Specific Gravity of Industrial Aromatic Hydrocarbons and Related Materials." 9. Dow References 9.1 Stevens, T. S., and W1ederr1ch, D. J., "Direct Injection Assay of T0R00N 101 - A Fully Automated Analyzer," ML-AL 78-00452. 9.2 Kracht, W. R . , ed, "TOROON 101 Mixture Weed and Brush Killer," Analytical Method No. 87120E. 9.3 Mujlca, M. L., "T0RD0N 101 M Herbicide - Validation of Assay," LA-ALM-80-001. 9.4 Roldan, J., "ESTERON 245-C Herbicide - Validation of Assay," - LA-ALC-82-001, March 17, 1982. AUTHOR M. L. MUJICA Mexico City nct fc.'.c distcibutsh " 0008215 t " - H l o t t August 3, 1982 "-- _. r- I J 7 of 8 pages FIGURE 1 LA-AMC-82-001 Calibration Standard Chromatogram pre-colunn: column: packing: eluent: flowrate: detection: injection volume: 4.6mm IS X 50mm s.s. v/ Co: Pell ODS 4.6mm IS X 250mm stainless steel Partisil 10-25 OSS (Whatman) 200mL acetonitrile/ liter aqueous 0.3M potassium dihydrogen phosphate/ phosphoric acid buffer pH2.95 2.67 mL/min uv at 280nm 0.512 ADFS LBC-1203 10 uL retention <fr tinea: p-bromophenol 10.0 minutes 2,4,5-T acid 32.0 minutes es es ft f ? 0008216 D '+ f i I August 3, 1982 e p-bromophenol 8 of 8 pages FIGURE 2 Sample Solution Chromatogram LA-AMC-82-001 pre-column: column: packing: eluent: .flowrate: detection: injection volume: retention times: 4.6mm ID X 50mm s.s w/ Co: Pell ODS 4.6mm ID X 250mm stainless steel Part is11 10-25 ODS (Whatman) 200mL acetonitrile/liter aqueous 0.3M potassium dlhydrogen phosphate/ phosphoric acid buffer pH-2.95 2.67mL/mln uv at 280nm 0.512 AUFS LDC-1203 10 uL p-bromophenol 2,4,5-T acid 10.0 minutes ' 32.0 minutes DOH 2111268 'O v i K V* ' r. T .. 7Vf Rfith L 1 L ? 26 22 r 1 Z - T I- rj /: .. z t r i iy r e* t4 i L' = rtPi 1 : U >r . L .1 . -I fsor ro.ici-rsics distribution 0008217 4 6 1 - V7// a -s* 4616 UNITED STATES ENVIRONMENTAL PROTECTION AGENCY W A S H IN G T O N . D .C . Z04S0 RtCEIVL L - 2 2 9a^ r - . > REGISTRATION iq P ? DON 2 1 1 5 8 2 2 Arthur E. Schober Dow Chemical Company P.O. Box 1706 Midland, MI 48640 Dear Mr. Schober: Subject: Description of the Analytical Method for TCDD ESTERON 245 BE EPA Registration No* 464-574 Your Submission of July 14, 1982 O > We have concluded that the analytical method for 2,3,7,8-TCDD in the butoxyethyl ester of 2,4,5-T is valid. The two analyzed samples of the technical contained 2 ppb and 9 ppb TCDD (0.002, 0.009 ppm). Sincerely yours. Richard F. Mountfort j Product Manager (23) Fungicide-Herbicide Branch Registration Division (TS-767) -f 00083:3 'JH.. if 713 July 14, 1982 DOW CHEMICAL U.S.A. MIDLAND. MICHIGAN 48040 D0H 2 1 1 3 8 2 3 Mr. Richard Mountfort Product Manager (23) Registration Division (TS-767C) U.S. Environmental Protection Agency 401 M Street, S.W., Rm. 237 Washington, D.C. 20460 * * 0 ^ Subject: ESTERON 245 BE EPA Reg. No. 464-574 Your Letter of May 13, 1982 Dear Mr. Mountfort: Attached is a description of the method and recovery data (chromatograms) of 2,3,7,8 TCDD spiked samples as you requested. Please note these data are stamped Trade Secret. We have decided not to offer the 16,500 lb. of material in 55-gallon drums for sale or use in the U.S. at this time. Thank you for your continued assistance. Sincerely, Arthur E. Schober Product Registration Manager Agricultural Products Department nbe Attach: bcc: Eva Ross (attachment) D. Buzzelli - 834 Bldg. E. Conyers - 9001 (attachment) AN OPERATING U N IT OP THE OOW CH EM ICAL COM PANY 0008340 UNITED STATES ENVIRONMENTAL PROTECTION AGENCY W A S H IN G T O N . O .C . 2 0 4 *0 RECjvt '" W 1 7 AKSISTRATlOh MAY 1 3 1982 Mr. Arthur E. Schober Dow Chemical Company P.O. Box 1706 Midland, MI 48640 Dear Mr. Schobert Subject: TCDD Analyses Esteron 245 BE EPA Registration Humber 464-574 Followup to our Registration Notice of March 29,1982 MN071991 ,, ,, 2 1 15831 He have completed review of your additional data on this subject submltte March 24, 1982. You are reporting TCDD concentrations within the Mwiimim (0.008 ppm) stipulated In your formula statement of Mirch 18. Since you have described this method as unvalldated, however, submit a method description an recovery data (Including chromatograms) of TCDD-spiked samples. He note that you also plan to submit further analyses of the 16,500 lb of material package in 55-gallon drums as they became available. He appreciate your cooperation in this matter. Sincerely Yours, Product Manager (23) Fungicide-Herbicide Branch Registration Division (TS-767) 0008341 ^ FIDENTIAL BUSINESS INFORMATION -DOES NOT CONTAIN NA TIQ&AL SECURITY INFORMA TION (E.O. 120651 Form Ap^.ovr.d OMB AJq. 2000 0 0 12 U.S. C N V IR O N M E ^ iA . ..,\o T E C T IO N A GENCY O FFIC E O F FESTICMVir, R O G R A M S |T S-77| Wa s h i n g t o n . O .c. 104*0 Q CONFIDENTIAL STATEMENT OF FORMULA ` BASIC FORMULATION a l t e r n a t e fo r m u la tio n See InstructInns on back of lost page. 1. N A M E A N D A D D R E S S O F A P P L I C A N T / N E G I S T I , A N T In clu d e i l l ` C o d e ) " " " a. 3. R E G IS T R A T IO N N U M O E R /F IL E SYMBOL 4. P R O O U C T M A N A G L H Dow Chemical U.S.A. P. 0. Box 1706 PAGE 1 OF 1 464-574 R. F. Mountfort Midland, MI 48640 S. P R O O U C T N A M E Attn: Arthur E. Schober S. N A M E A N D A D D R E S S O F P R O D U C E R (Include ZIP to d ) The Dow Chemical Company Michigan Division Midland, Michigan 48640 ESTER0N 245 BE Herbicide 7. W EIG H T/G A LLO N DENSITY 9.42 lb/gal. 0. pH . FLA SH PO IN T/FLA M E fcXTCNSION 2.8 diluted 10.1 with water 175F (TCC) 10. C O U N TR Y W H ER E FO R M U L A T C O USA C O M M E R C I A L C O M P O N E N T (L itt each a actu a lly In tro d u c e d In to th h form ulation. Give Trade S am e (If an y ). N am e o f Supplier, and SPA H eentratian Num ber If applicable.) ti. supplier 13. CPA R E O . NO. 14. W E IG H T O F EACH COMPONENT* 19. P E R C E N T io . p u r p o s e : in BY W EIGH T FO R M U L A T IO N 2,4,5-T, butoxyethyl ester associated Impurities max. (2,3,6-T butoxy ethyl ester max. 0.8% 2.4- D butoxyethyl ester, max. 0.4% 2, methoxy-4,5-d1chlorophenoxyacet1c acid butoxy ethyl ester, max. 0.2%; 4-methoxy2.5- d1chlorophenoxyacet1c acid, butoxy ethyl ester, max. 0.2; 5-methoxy-2,4dlchlorophenoxyacetlc acid, butoxyethyl ester max. 0.2%; 2,3,7,8-TCDD less than 0.008 ppm) GAFAC RE 610 GAFAC PE 510 Aromatlc/allphatlc petroleum solvent Dow Chemical GAF Inc. Il II Many sources 464-491 60,900 2,300 3,500 33,300 59.1 1 .8 Al Impurities 2.3 3.5 33.3 CO emulsifiers "a solvent tv v / h ' O CD CD TXT CO II liquid measure, give specific gravity or pounds per gallon. I. T ^PJO n a Mc o f a p p r o v in g OFFI Arthur E. Schober ERA Form 8570-4 (Rev. 10-811 p r e v io u s e d it io n is o b s o l e t e . T66t0M" cn <30 CO I 7. T O T A L W EIG H T O F BATCH 100,000 lbs. I*. TITLE 1 0 . T E L E P H O N E N O . (Include Product Registration Mgr. lf5T7')-636-6277 21.' BATE---- March 18, 1982 O RIGIN A L COPV TO EPA APPLICANT RETAIN S SECOND COPV U * I / m 8 8SI IZ moo 1 DOW CHEMICAL U.S.A. MICHIGAN DIVISION March 19, 1982 midland. -Michigan asmo A. E. Schober H&E Sciences 1803 Building cc: C. H. Goodman, 2030 ESTERON 2,4,5 BE-TCOO ANALYSIS Currently our inventory of BEE 2,4,5-T technical ester is made up of one bulk tank which contains about 635,000 pounds of product and 16,500 pounds of product packaged in 55 gallon drums. The bulk tank was sampled on March 2, 1982, and was analyzed and found to contain 2 ppb of 2,3,7,8 TCDO. The analytical research method used is an unvalidated research method with a detection limit of 1 ppb. I have attached the raw analytical data which includes the chromatograms. All of the product in 55 gallon drums is from one production lot and will be sampled and analyzed next week. I will communicate the results as soon as they are available. D. T. Buzzelli Ag Chemicals Production Environmental Services r Attachment AN OPERATING UNIT OP THE DOW CHEM ICAL COM PANY f ? P,53 S"3 4622 Q-Hfl*