Document 91061a916QavEMNOBzoj72mp5

18 2* lb itUiaw* of natetiK aMtoti am apparent aaanc tint rabbits m!i of aUeb sas glean 75 nMtalit oral doaoa of 0.269 gm par kUigm f body wight, an Hh af flu days par rook, w a poriod af 106 days. 3* Bata fad dlata sontalalng 200 p.p.w* 2000 aad 20,000 p.p.n. af San-Malar B-i6 la thair dally dicta ahawd as taalo affaata or Ntudatiw af gnitlu 4* faa dags, aaah (twa a dally aral daaa of UaO m$a, of saatlalaar P-16 far two yaora, dhtaad aa toala affaata or retardstian of growth* IT. tartraatlaw Stadias^ taa-adl palywlayl ahlarlda filaa plaatialaad with tarty! pfathalyl bnty! glyaallata (taatiaiaar Bl6) wara aaat fha 20^ oollda aalatlao la ayslahaaawaaa iaawriHig to tha aathad af Hha, Alfray, Jaaaaa, aad taurh, "Jamal af Palyaar Salhaaa", 2, 179 (April 1*7). tasaarwh raaaalad that tha saatlalaar >-16 aaataat af plastlalaod filaa aawld ha dotaralaod hy infra rad apaataiaihat aaatry. --aaaraaaata aada aa anah filaa aantalwlag Saatlalaar H6v ta 800 shsswd aa afcaorptlaa haad at 1540 1', a rsgtaai did la aaifly *>> fna latsrfsrlag abaarptlaa ofpolyrinyl ahlarlda. lard, aad paaaat ail* it was thara* far* yaaafhli ta satahllah awna af aptlaal daaaity aa. paraaat laatiaiaar M la tha film aa ahaaa la npn XT* Rw thla awna. tha paraamtaga laaa af Saatlalaar B-16 fina tha aatraatad fila aawld ha dlroatly drtintart. ipprwalaotsly 1" dlaaatar poaahlaga fra* tha aaat filanara fhataaad la allp^typa hraaa riap aad tsaplstsly Iwsaraart la tha foUoaiag aaltwwta far 2b Ira** 7 daya. aad 30 dayat Pouat oil at 2^ C*. 08* 0* aad 110* e* para uurd at c*. 80* 0*. aad 136* 0* tartar. pH 5. at e. aad eo* e. taitar. pff T, at C. aad 80* c. tartar. pH10, at fdO c* aad 80* c. tha f--ralaw waa dm la aaah a aaaasr that hath a&daa of tha fila wus la aaaylsts aontaot with tha aalwasts* Aftar raaaliving la tha aolaaat far * haw, tha filaa wara resswad, tha plaatlaiaor aaataat dataralaai aad tha aaaa filaa raplaaad la tha raapaatlwa aaloaats far tha 7 day's taat* Thaaa filaa whish ahaaad aaaaidarahla sartrastlan aftar 7 days *a aat asnHmad far 36 daya* ^Tfels partlda af tha study waa parfarwad hy tha Hasuaato cbanlaal Co*, st. bawls, Klaorui 20458019 -tk. / 4 BFG03539 19 BFG03540 80- thi taffsr solatisas used far the wlaw a^uaoua niatlM w fnpin4 m foil--it 107 _ *i k titrli v* mm add* V *36 ml lAo Bml Diluted te 1000 ml. 0.8 BW% 59.26 ml MB Misled ts 1000 ml. Misted te 1000 is add!ties te the aatraetlan teete deeerihed shews, Ike effSet em tie pfagrsiesl prepsrtlee of Him ehem Is eeataet with ele--rgsrlas tmr k$ hears *t 87*C* ** determined. Snt sswplds 9* leaf. 1" wide, emd sp- frwdMtelj 0*OOU* thleh* sestetslac 90 parte Ip weight WnttiiMT M6^r 100 parts deem reals 008). mere eapeeed te Dslrleh eelered elesemrtnrtae. A twMtp ef the els--rise was epiwad lste class takSso dlah sad the film stripe - previews!? --Itl--I fir leB Users were pissed ea tap. Another leper et ele--uprise wss pissed seer Iks tap ef the film, time exposla* hath sides af the film te the eslrsstln sffiste ef the sla--rgarlne. Os dlih wh them pissed Is the --test te--raters ream (87* c.) far itO hears. The films were nested, ell <s> sees ele--rpertoe wiped eff. ead demdltleaed hr til hears at 87* fa The tensile strength, msdwlas. ead elamcptUs were detsrataed em the a--ead fils sad eeapared te elsilar data ef --spsssl film. t. asewlte The remits ef aapeslac Ike 1" disaster fils p--hints te werises eelwwsta seder the sendItI-- ae netUsed ahswe. mere ee fell--i Selwrat Bsgrss ef kc--etlas * ISrstst if OrifMsl plsstleissr esetsat ef film estrastede TS-- *c. After fill hears After T dsrs 10 d-- mast ou fsaaat Otl fssaat Oil Pare Urd Pars lard Pars isrd nstsr-pH 9 mster-pH 9 interns 7 kkh*H7 mstwr-palO satar-*H 10 t^e. *e 110* c. a#c. *c. U0*c *6* c. ao* c. tdh c. *c. ado e. 00c. IkJO m IW m m ifloo % % fTsset m to* ttsf* I0Q* W( ws 50.# 13.# oat m < a* *# *# m ** Initial plaatieleer eastant sf fllme waa 80? asmtleiear B-16 in oaaa 80S. BFG03541 20458021  ei Aam ro*aU abav that at c. aad 100* C. paaant oil aad lard offaot NtMtteUr a fatal mtraotian of Saa&lalaar B46 fro* tfco fil* attar alt baara. At *4* c* tba aaaoat mtraatad by paoznt all aad lard daaa mat appaar to Va aaattlM was aftar 30 daya* AMv data not barn aa aarlaua aa offaat oa Saatlalaar B"l6 aa do tba altar olront*, aad tba pX daaa Ml ppaar to bo * oitalflooat fbotor. Imrmood tonporatwa tlpilflauiMy laaroaoaa da artmUM by ntor bat aa* aa iaoroaoo la not lrtttelly aa affiwdM aa la tho aaat f paaaat all aad lard* Aa rawlta of mpaatng tba film taat atrlpa lantafilat 30 porta saatlaiaar Hi to ilaowrpniM aara t fallaaai Mm ifw Hrta a?J-SSg------- flaatl- x Bad* r.s. X bad. ??. x art. asfgM&y *2s~c*. 1 el. jcl_I as. bL i ML rtatlalaar fr*6 5O9M179a0UQOllO115l9t9 Aaaa film aara tatbar poor duo to tba dlfflaalty af aaatJj kUanU polyvinyl ablarlda aalvtlaan. bwat, A* data ladlaata ibma Aat palyvlayi ablarlda film plaatlalsad ilth aaatlaltar H6 daaa aat Idaa ita phyalaal proyartlaa rttaa oapaaad to tliirprlb. e. caaalaalaaa Aa a raaalt af tba aatraatlan atudlm tba fallaalac aaaelmlam aaa ba aadat _ UAtMr c.. tba aatraoAbility af saatlaiaar Hi by paosat ail. lard* aad aatar la valatltaly laa. X. At C. aad us* o. virtually all af tba flaatialaar B4i la aatraatad by tba paaaat all aad lard la % baara. 3* At OB* o. tba aatraatlaa af bttlalMr Hi by aatar la aaab raaar tbaa at t# bat 1M|C aatraatlan rafrtraa la aaaaaa af 7 daya 1--ralnai U. Aa pX af tba aatar daaa aat appaar ta bam a aiprtAaant afftat aa tba aattaatabUlty af Saatlalaar Hii 5. film aantalalaa saatlalaar Hi atill ratal* caad pbyoiaal yryirtlM aftar U* baara aapaaura ta alaaaupfvlaa at ST* 6. 6. A Ala aoatolalag "ostialir Hi abanad aa laaraam la tamila otronjtb aad aadalaa altb practicably aa nhanga la alanpitlm aftar oxpoowo A daamriarim far US baara at S7* c. 20458022 BFG03542 /I BFG03543