Document 8VZ68LovD4qB0MKN1dEm6MegB
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7
Johnson
BABY PRODUCTS COMPANY
- RARI N.T J. A 088N 69
February 8 1977
SUBJECT
7
=
Special Talc Studies -- JBP Respirable Particle Measurements
Project 20503.01
During
Adult
Usage
PROTOCOL
Adult Powdering Protocol 2636.01 6429.12
Available TITLE Assessment of the Amount of Respirable Particles
:
Shower Body Powdering with
for Inhalation During After
lL
' JOHNSON'S Baby Powder
TO
Mr. G. Lee
7 Ten adult female and ten adult male users of JBP were tested
The amount of respirable airborne particles to which they
-
were exposed during their normal after shower body powdering
oO
procedure was measured
The measurement was accomplished by sampling the air with a
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10mm nylon cyclone immediately adjacent to the nasal openings
during the actual powdering procedure The mass of respirable
collected by the cyclone was measured with a Thermo
particles 3210A quartz crystal mass monitor
The summarized found in the
Systems
data is presented below
Detail data may be
|
attached appendix
A. Powdering Time Exposure
. 7
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This is the time during which the subject applied the It is also the time during which the respirable
ppaorwtdiecrle concentration measurement was made e.g. the
exposure time
B. Powder Used
This from
is the a full
weight of powder in grams the subject
9 oz container of JBP code 240G
used
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Special Talc Studies- JBP
Adult Powdering Protocol
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C. Average Exposure - Concentration Mg M
This is the average concentration of respirable airborne
particles to which the subject was exposed during powdering It is obtained by dividing the mass of the respirable particles collected by the volume of air sampled
D. Peak Exposure - Concentration M
s
This is the highest average concentration to which subject was exposed during any 10 sec interval of
total exposure time
the the
Summarized Data
10 WOMEN
Average
Mean
|
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10 MEN
Average
ot
Mean
o ~
~
COMBINED
Average
Mean
Powdering Time
'
Exposure
87.1
Powder Grams
Average Exposure
Concentration Mg
8.16
1.27
Peak Exposure
Concentration Mg
95.0
72.2
7.85 1.10
13.02
1.94
2.00
--
58.0
79.7
7.20 1.29
10.59
| 1.61
1.67
87.0
7.85
1.14
2.00
Averages not possible since some readings
of 3.00 mg M3 on the TSI recorder
exceeded
the
range
maximum
Discussion of Data
1 The average adult exposure concentration 1.61 1.61 mg M3
is about times higher than that found for babies
0.21 mg mduring normal powdering and diapering
period Also the adults were exposed for a longer time
;
for babies 80 seconds as compared to 4.6 seconds
the
JNJ 000088302
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Special Talc Studies - JBP Adult Powdering Protocol
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2 The men tended to powder in a shorter time but used
more powder and created higher particle concentrations on an
airborne average
respirable
than the women
A copy of this report is being submitted to J. Sivertson with the request that he use the attached detail data to calculate estimates of the safety factors in the Battelle
Studies when projected to adult usage
by attachment - Appendix I
-- -- ,
R. S. Russell
.
cc W. H. Ashton
R. Marshall
Merz
Seltzer
Semple
B. Sherman Sivertson - attachment - Appendix I & II
Waggoner
.
Kulkarni
-
Health Care
-
-
attachment
Appendix
I
&
II
JNJ 000088303