Document 8RmnK3a9mbEeMQ38v5LK3vEqd

HHeeaalltthh CCoonnssuullttaattiioonn 33MM CHHEEMMOOLLIITTEE PEERRFFLLUUOORROOCHEMMIICAL RELEEAASSEESS AT THE 33MM -- CCOOTTTTAAGGEE GGRROOVVEE FFAACCIILLIITTYY CCIITTYY OOFF CCOOTTTTAAGGEE GGRROOVVEE,, W WAASSHHIINNGGTTOONN CCOOUUNNTTYY,, M MIINNNNEESSOOTTAA EEPPAA FFAACCIILLIITTYY IIDD.:" MMNNDD000066117722996699 FFEEBBRRUUAARRYY 1188,, 22000055 UU..SS.. DDEEPPAARRTTMMEENNTT OOFF HHEEAALLTTHH AANNDD HHUUMMAANN SSEERRVVIICCEESS Agency for ToxPPiuubcbllSiiuccbHHseteaaalntttchhesSSeearrnvvdiiccDeeisease Registry Agency for Toxic Substances and Disease Registry DDiivviissiioonn ooff HHeeaalltthh AAsssseessssmmeenntt aanndd CCoonnssuultltaattiioonn AAttllaannttaa,, GGeeoorrggiiaa 3300333333 Exhibit 2009 22000099..00000011 HHeeaalltthh CCoonnsusultltaattiioonn:: AA NNoottee ooff EExxppllaannaattiioonn ArAennquAAesTTtfSSoDDrRRinhhfeeoaarllmtthahtcciooonnnssuuslblttoaauttiitoonhnesiasltaahvvreeirrsbbkaaslleoolfratwweirdtittoteenn2srrpeeesscppioofnnisscee sffirrtoeom,maAcAhTTeSSmDDicRRalttooraaelsseppaesececi,iffoiiccr cttrhoehenqesuuepplsrrtteeassfteoeinnroccnieenmfoaoorfyfmahhltaeaiazzodaanrrtddaooobuuossspuetcmmihafeatiaetclertrihaiacaltrl.ii.soknIIssnn,reosolruarddcteehedriatsotlooraesppstrrpreeeivvceeetinnliitntcg soouirrtsee,mmoaiiflteiihgogearalmteeriecpeealxxtappcrooiesnlsueguraresweseas.,,teo&arr ccssouounppntppsalulimiletissan;;taioiitnnnettdeemnnmssaaiityffeyryliiienanalgg.d eetnnovviisrrpooenncmmifeeincnttaaalcltissoaanmmsp,pllisiunngcg;h; saesstrreisctriincgtinsigteusaeccoesfs;ororreprleamcoinvginwg attheer. restricting site access; or removing the contaminated material. IIcnnondaaduddcditittiiinoognn,,heccaoolnntshsuulsltutaartvtiieooinnlsslanmmcaeayyactrrieevcicotoimemsmm(ee0nneddvaaaldduddaiittieiooennxaapllosppuuurbbleliicocf hhteeraaellnttdhhs iaanccttaiioodnvnses,r,sessuuhccehhaltaahss coporouuotntcvcdoioudmmcietenissng;;ghccheooaennladdtluuthchcttesiidnunugrgcvaebbtiiilioololalnoonggcifieccoaarallchtiiiennvaddiltiiticcehaasttcootarorrsseeoovffparleeuoxxvappiteodoseseruuxsrrpeeoasssnttuduurddeciieeoossrmmt(toruennaaisdsstsseeysisnssmaeeedxxmvppboeoesrsrsuuserr.eeh;;eTaaahlnnitdhsd. pcocoborotnnavccilildunuieddndeegssbyhtthheAeeaTlhhtSheeaDalelRttdhhuwccchoaointncisoshuu,nllttiaafntotiitroohnneheAppagrrloeothcnceecssycssa'rsffeooorrppirttahohiiivssoindss,eiirttiesen,,daiuuncnnadllteeesscsssoamaanddmdedieuittdniioiottnnoyaarllemviiniensmffoeobrromemrraasatt.piiopoTnennhdiiiss.s ttohhbeetaccioonnnecdclluubssyiiooAnnTssSppDrreeRvviiowouuhssillcyyh,iississnuueetdhd.e. Agency's opinion, indicates a need to revise or append Y`Yoouu MMaayy CCoonn1tt-aac8ct8t 8AA-TT4SS2DADTRRSDTTROOLLLL FFRREEEE aatt Visit our Home P1a-g8e88at-:4oo2hrrAuTp:S/DwRww.asdr.cde.gov Visit our Home Page at: http:llwww.atsdr.cdc.gov 22000099..00000022 "This document summarizes public healthFFcOOoRREEnWWaOOctRReDDharzarndosus waste site in Minnesota Its Tbbfaaohsrsiemesadddlooosnnciutaaemffeeoovnrramtlmuasaaulltmsisioimttnee,aeeraivvzanaehlusuamaptbtuiieobornnliocppfrrheseetppaeaalprtrsheeaddrceobbnnyyectctehhereensssMMaiarintnynan:eehssaoozttaaardDDoeeuppsaawrrtmmaesetnenttsoioftefHHeinaelaMlttihhnn((MeMsDDoItH)a..).ItFFioosrr aa formal site evaluation, a number of steps are necessary: EEevnvavaliluruaoatntiminneggnetexaxlppoocssouunrrdeei::tMMioDDnaHHs hsscceiieesnnitttiiess.ttTsshbbeeeggfiiinnrsbtbytyarrseekvvsiietewwoiinnfgginaadvvaoaiuiltlaabbhlloeewiinmnffuoocrrmhmaacttoiionontnaaambbioonuuatttion eMiissnDppvrriHereossenednnmottg,,esnwwnthahoelerrcceeooniiltdtliieisttiffoiotonususnnawddtnoothnneettnhshvieetiesrs.iiotTtne,m,heeaannnftddiarlshhtoostwawasmkpppeeliooispnptlgoleedfmamintiiadgg.hohRtuabbtteehheoeerwxx,ppMmoossDueecdHdhttocoroeiil.nti.teaUsUmsosuunianalallltyyio,,n M EiinnnffDvooirHrrmmoadantotmiieeoosnnntnpaporlrtoovcPviroioddllteeeeddccbttbiyiytosntthohAewegnM Meineincnnnynveeis(rsooEotntPaamAPPe)onolatlalunultdtisiooaonntmhCpCeorloinngntgotrrovodlelartAAamg.geeRennnatccthyyaeg((reM,PnMcCPiACeDs)AH,,)p,rrettihlhvieeeastUUeoS.Sn.. Ebunsviinreosnsmese,natanldPtrhoetegcetnieornalApguebnliccy.(EPA), and other government agencies, private businesses, and the general public. EEevxvapaloluuscaertdiin--nggtohheehaaallztthahreedffoffeueccsttsss:ubIhsftetahnrecreees,iissMeevvDiidHdeesnncccieettthhiaastttppeewooippllleaaakrreee bbseetiiennpgg teeoxxdppeeotsseeedmdi---~nooerrwcchooeuutllhdderbbee tthehhxeaaptatoleesxxtepphdoo-sst-uuhtraorteehiccsao,ozuutalhlrdddobhbueeeaslhhstaauhrrnbmiasfmftuauplnlaccttooetshoh, unuMmmtDahaennHchhoseecmaaimleltunh.nt.iisM MttsDyDHwaH'ils'lsatwrarheekoppelooresrttt.effpooTscchuuteosseerdsseepootoennrrtmppuiuisbnblbeliaiccwsehdetohner existing scenic informa. health-- that is, the health impact existing scientific information. on the community as a whole. The report is based on DDreeegvvaeerlldooippniignngagnrryeeccpoootmmemnmetneidanaldtahietoiaonlnst:sh:tIIhnnratththepeeovvsaaellduuaabttyiiooansnirrteeeppooarrntt,d, MMofDDfeHHrsooruuettlcliionnmeesmseiitnssdccaootnniccloluunssfiiooornnss rrrWeeeigddtauuhrccdhiinainnzgggaoorarrdnoleyuliispnmoiwitnnaeaanstittiinnaggil thhhesuuammlitasahnnptrheeirxxmeapparaotisslpuuyorreseaedttvdooisbccoyoornnyat.taasmmiFitenirnaanahntndsat.so.frTTfeehharseesorrnrooe,llceteohmooeffmeMMveaDDnludHHaattiiiinononnddseeraeafolpliiornrngtg wwwMiPiilltllChytAhyp.apiziccIafaar,dlllhoyyouwrrseeewvccoeaormsm,tmemaeesnnnitdidemsaamcicesttdiipoiornanimstsetoaohriebblayeeltatthadakkvteeirnsneoabbrtyyy.eooxFtbihoseterrsrt,haaMaggtneDrcneHicacisesows--ni-i,l-intnhiccesllusuedudvieaainnlugpgaubEtEiloPPinAAc rhaaeennpaddlotrht MadPviCsAor.yIft,ohwoawmevpeero, palneiomftmheedidaatnegheeraaltnhdthwirlelatweoxrikstst, MreDsoHlv~evtihll ispsruoeblaemp.ublic health advisory to warn people of the danger and will work to resolve the problem. SSsoollliiiccciiittininnggg accnoodmmmemuvuanlniuittayytiiinnngppuuirt:n:fTTohrhmeeaetevivaoalnluufaarttioioomnnvpparrrooiccoeeusssssgiiossviiennrttenerrmaaeccnttiitvveea.g.eM MncDDieHHs,ssttaahrrettssinbbdyyividuals ootsrhoroelroicsgrtigateian.nnigziAzanaatntyiidoocnneossvnacrrlleeuussapsptiooionnnnsgsisibbianllbeeffoofourormtrtcachltlieeoaansnniiiftnnroaggrmuuppvstahthhraieroeussdisttwe,g,iotaavhnneddtrnhccmooimmennmdmituvnnaingidietutanyylcmsmie,eesmg,mbrtoehbueerprssisn,ldiiavivnviidnindggunanelesaarr toophrrregegpaasannirtiieezz.daa,AttioinMnoyDnscHttohhnasactelppeukrrsosoiovvfniiedsdeeeadddbbttaohhcueekt iitfnhnrffeooormrsmmitateathtieaioropnenu.b.slhOiOcan.nrcecJedefaywannoituheevvhtaahallveuueaaitntqiiduooeinnvsitrrdeieupopaonolrsrsott,rhhgaacrssooubmbpeemseee,nnnatnsd abort phirespraerpeodr,t,MwDeHesenekscfeoeyduobaucrk0cafroongmtatehce us.public. Ifyou have questions or comments about this report, we encourage you to contact us. Please write to: Please write to: CSCiootmemmAmusnusinetistsyymRReeneltlaatatiinoodnnssCCo(~onoosroudrldiainntaaottonorrUnit MM S1i2itin1ennnAEeeassssosottetasaSseDmDveeeepnpnatatrhrattmnPmldeeanncCtteooonSffsuuHHiletetaaaeltlitt2ohhn0U/nBitox 64975 S1t21PEauals,t MSeNve5n5th16P4l-a0c9e7/5Suite 220 / Box 64975 St. Paul, MN 55164-0975 ORcallus a: OR call us at: (((C66ol55l11)f)2e2e15a1-l0l9-5p1r6oeo-srrs11-"0-8480"00o09-n-6655y177o--u33r9690o08u8ch tone phone) (toll free call - press "4" on your touch tone phone) On the web On the web: hhttpp://w:ww.hheeaalltthh.ssttaattee.rmnnn.uuss/ddiivvssi/eehh//hhaazzaarrddo0uuss//iinnddeexx.hhtmmsls 2 22000099..00000033 `TabTleoaoff CbCoonnltteennettss Summary. -- soa 4 Summary...............................................................................................4 Purpose. i. s Purpose ................................................................................................ 5 BackgroundandHistory. -- 6 Background and History ............................................................................ 6 Geo/Hlydroogeoglogyy....... rte - 7 Geology / Hydrogeology..................................................................... 7 SuperfundSiteHistory. m---------- ies Superfund Site History ...................................................................... 8 Areasof PEC ProductionandUse. rn a0 Areas of PFC Production and Use ....................................................... 10 On-SiteGroundwater Monitoringand Use........... LI On-Site Groundwater Monitoring and Use............................................. 11 PEC Monitoringatthe Ste. rll PFC Monitoring at the Site ............................................................... 13 Site Visit. inm--------------g Site Visit..................................................................................... 15 A Public Comments ........................................................................... 17 DISCUSSION... ttn Discussion ............................................................................................ 1188 Summaryof Toxicological INFOTMAION...... cco verre] Summary of Toxicological Information ................................................. 19 Summaryof EpidemiologicalData. A Summary of Epidemiological Data ...................................................... 22 Summaryof Environmental Data 2 Summary of Environmental Data ........................................................ 24 Planned ACUONS......orerorer ee . 2s Planned Actions ............................................................................25 CChhiilldd HHeeaalltthh CONSIAETRHONS........rrer es rrr Considerations .......................................................................227 CCOoMnEcRluIsSiIoOnNsS..............r.o..r....v....e....r....s....e....s..........o..s..r.s..e..s..o.n..o..e..o..s.o..s..e..o..s.o..s..o..r..s.o..s....22]7 RECOMMENAONS..... oon 28 Recommendations....................................................................................28 Public Health Action Plan... 2 Public Health Action Plan .......................................................................... 28 PrepoaftrheeRerposrt... --- 8 Preparers of the Report..............................................................................28 RERSencmmmmommonasmmammmmm-------- References ............................................................................................29 Appendices: Appendices: AAppppeennddiixx II:: DDVeaerlriuivveaasttiifooonrn oPofRf MOMSDDHaHndHHePeaaFlltOthhA--BBaasseedd VVaalluueess aanndd SSooiill RReeffeerreennccee. AAppppeennddiixx III:: PVPuubablluliieccsCCfooormmmPmeFneOntStssRaRencdeecPeiFivvOeedAd 3 22000099..00000044 SSuummmmaarryy 2p233r0M 0Mo00d22ppurrc((otooodsdnnauuwapcceieeprddlieloopptpeterrrssoffccldlaauuulloceoererooodroc,richhinhneeammnffiuudiclclllalaelpldpssr,roo((uddPPusuFFcccCCtdtisisooo))nrn)aa)pt,t,attucuhhsskeeiiainrrngggeCCodaaotnntattteeaallggseeeeeccvttGGerrrroroaofofllvvlueleuooorffcroaaaoccctcihiihlloeeiintmtmysyiicafcftararollotmhmpperrtotohschiceeteees.slslasa.tt.eDeuPP11rFF99i4CC4n00gss until until pp`pWrrrooaosdddtuuuecccstttisifoorwnno,,eamraieitrrhepeemrmoPidsiFsusCsicieoopdnnr,sosdhoouaffcntPPdiFlFoeCndCs,puroocoscecccudeursrrosreerwddp,e,araacennkdddaigmmsepadaoyysaethhdaasevviveeneaeeraxnxlttoeelnnon-ddcseeaiddttioeoofnpffsif,ttahhteaenthdsseiitptesoistppesrr.ioobppDleeyrurttiryynin.ogff-site W laloodccjaaaasttctiieeoosnnntfssrMoaaimssswwsetihleslle.il.PppFW WiCaasRsptitreveoewwdraautftceeotrriodttnrerecepaaatrdtmoemcseee,nnsttnsppdwllaaennsrttleueeddffigffsllepuuoefennsrtetodmccooitnnnhtetaaaniwinnaoiisnnntgg-eswPiPtaFFetCCepsrsit,twwraaaenssadtddmpiiesosnccsthshiaapbrrllggayeentddinattoonodfttfhh-eseite apwpdeoorjnnaeddcsseanltthshtaoaMttuccissooesnnditstaaastiiinpnaepeddiirRPPeFiF-vCtCeassrifnwwoieernrrgdeeeaaacrllaessdaooeodsdn,iissatppnhooedssewesdedlousodtnngsessiiidtfteere.o.omfFFittihrhreeee--fsfwiiitgega.hhstttieinnwggafftoeoaramtmrsseacctoomnntetanaiitnnpiinlnaggntPPFaFnCCdss were also used at a fire-training area on the west side of the site. Ts"Tihhtee irrseescsuuolnltttssaoomfilfniliammtieittdeeddwieetnnhvvipirreoornnlmmueoenrntotaoalcl tmmaononenitistouorlrifinonnggatttooe dd(aaPttFeeOiiSnn)ddiiaccanatdteepttehhraatftlggorrrooouuonncddtwwaanatoteierer bbaeceinndeeaa(ttPhhFttOhhAee), sgiinnirtoessuooinmsmdweceaotllnoeotcrcaa.amttiiionoTnnahssteefaaduttlwllleeivvteeehxlltsspeesnsriitfgglonnufitioffhiricoceaaonncgtttrllayyonueiinnndseeuwxxlacfctoeeenssrssaotcoefofn(ttPthhaFeemOiMMnSDaD)tHaHinodnHHepheaaealsrlttfhlhnu-o-BotBraabosseoececddntaVVinadaoleliuunceiesfasic((ciHddH.BB(PVVMSFsu)O)cAffhoo)rr, ogopfrrfoottdhuhuenecdcctwooinonanttteaawrmm.eilinlnTasah,tteeeaddfnudgglirrlooeuuxpnntreddonwwctaeatsotesefrertdhiisestcchgoorrnoontuutaagniihdnnweehddeataaesnnirddtcecocwoonalltslaletmcceitwieenaddattebbiroyynraaahnnaieesmxxentteeonnnttssbiipvevleeeannsts.yyidssettTenehmtmeifoiopefflda.ntMhauschnot phaHidirssdottidooturriiicocctnaaiollollnyfyawbbeeeleelalnrnsg,aaeabbgnllredeatn1iosulprraerermomcaoocevvtsieesvettadhhteeethdPPrcoFFauCCrgssbhoffnrtrohotmemresttaihthteeemweeenffatffsllustueyeewnsnttta..etemHHrohotawrweseaevetvemferfree,,cnthttihepveelalrryneectcl.eeinnTmttih((ne22a00pt00le4a4d)n)tPhFaCs not adAdidrissedccaihht)iaaorrinsggeenossoftttaooclattahphrteegueMMriegsidrssasibnisysusslitiapphrppeiaipcRRrtioiivvdveauertcr.e.tdiAAocnnanrwabaerroleelnaas,toorfeafansstdhhmaalellilnlkooetwlwsyyggdsrrtoioeumusnncddhwwhaasaatteetrefrrofgetccecohotnsnievttaaeMmmliyisinsneailatistmisioioinpnnpa((itiienRdittvhPheeerF.CDDI1 ATn"Tohrhteeeabee)effefifseneccndttoessttooecfrfampppiaatnsusetrtdedd.diissbccLyhhoaatwhrrggeeelpessvrtfeoooldsttuhhoceeftiM PMoiFnsiCsswssiiessslmsliiaspp,yppaiinaRRdsioilvviekbererelooydnnidsssicuushcrraffhraaagccreeegdewwsataottteoterhr,t,ehssereeiMddvieimirmsebseniyntstsstsi,h,pepoorriadRbbjiiiaoovctteeaarn.hhtaave:e Esgles Point wastewater reatment plant. not been determined. Low levels of PFCs Eagles Point wastewater treatment plant. may also be discharged to the river by the adjacent mSSooaiiyll ddmaaortvaaeffoocrrasPPiFFlCyCsswiwwteherreeinnnfiooltttraaavvtaiainilglaawbballteeefforotrththhroeussgiithtee.s. oBBmeeeccasaouuissleetoyopffettshh,eeiirrresppuhhlyytsisiniccgaalilnppgrrroooppeuernrttdiiwesas,,tePPrFFCCss c`mccaooapnnyattabammlmeiooinnvafaettieieoonannts.e.ilryiTTnhwhgeeigthllriimomiuniinftteidelddwtraannttuuienmmrgbbfewerrroamooteffsrssotttuhuurrddcoiieueessgahrrreeesaggosaamrr(ddseiiunnscgoghiaPlPFFtyCCfpiermmsei,-iggtrrrreaaastituniiloiotnningnssgsuutgigcngsge)egssrtatonuttdhhnaadmttwoPPvaFFitCCenrsgs aalrroeeng cdtdihaissepttaaeabnancslceeteoss.of.fteAAhnnenatealfrlycyisnisigilsstogyofrfodwwuiadnatdteneworrtasstsaaehmmropfpwlrloeetmsshffsoooprruPPrrcFFeeOOaSSsreoaaeannfsddne(isPPctuFhFceeOOhrAAacshfferfrmoiorimecm-atlffro.oauuinrrHippnorrgwiivevsaaviitteeecrsww,)eaeltnlhlldess wmlloeoocclavasttieneaddgrjjeuluossnttgttoo `tcghorecomueponaldsetmwteaodtpfaetarhlsesifieglgfnoanwitc.ififilieicctTaaydhnne:dt idddaiibssnsttoaeatnnncccseheeoobbfweellPotohFwweCspggrrroeionsuuentnndhdce,,seaaeonnwddfeelaailrrtseehediirnnoceaahssseinimddoetei-c-rgagurlr.laaeddHioieeuonntwttteddhivierreeeprcc,ottstiishooiennbiwiilnnetlttyleoesrrfmamrssePooFfCf gcscoouronbntustaaenmmqdiuwinenaanatttteiiornonfnflloiir~nnavggt. rrioToouunhnneiddnawwtbaoasttegeenrrrocuooennnodowofarrPotofFeffrCof.soffitTnthhhteiehsessstiietretawnaasessploaalsrtrrdeemssoueuelclstthnooaoffntaaircesurrmliaealliosdduteethpptooohusseigithtpiitooonstnsoioohbffailPPviFteFyCCososcfcaauPnnrFddrCed (andi beinginvestigated) at other PFC facilities in the US. subsequent infiltration into groundwater. This transport mechanism (and is being investigated) at other PFC facilities in the US. is thought to have occurred f`WaWcooirlrkkiteeyrr'sss aawttattthheeersssiiuttpeephhlyaa.vvee3bbMeeeennhaeesxxmppooonssieetddottrooedPPFFwCCorsskttehhrrrsoouautgghhthttehheefiairrciwwlioetrryfkkoraactctthiivveiittpiieressesaaennnddcettohhfrroouPuggFhhCstthheien thtcfhaeoecinicirrlebibntlytloor'sooatddwisaositninenscorceefstuthphPepeFlyO11.99A77o030sfMs..uhpSSattstuuoddmii1eeo1ssn5iootpfofarPPretFFdsCCwpeccoroornnkmciceelernlsntitraoratnattt(iihopoepnnmfssa).icinnilibbEtllypooiofododdermsstieheoreruluompmgriehhcsaaeavvnleecsestshuhodoofiwwcPsnnFoCfs in wmwcoooorrntrkackleeeirnrtsstyr.aaatttioECCponoirstdttoeaamggfieePoFGGlOorrgooAivvceeoalhfhaaudvvpaeettaosshhf1ooo1rww5tnnhpelalsiirtetttsllceephaaeepprmppimacararielellnnistotniiimm(lpppaapaccmcktit)n.oogfffEoPPprFFiCCdteheemexxgippoeoolnsoseuugrrariecelaooplnonsptwuwulodoaritrekkiseoernro.f mortality. Epidemiological data for these a chemicals is lacking for the general population. 22000099..00000055 SuStbtuiudqdiuieeists oooufsf PPiFnFCChssumiinnanbblloboloooddodss,aaammpplcleeosnscfferrnootmrmattthhieeogngesenmnereuarcalhlppolopoupwluealratttiihooannn hhaavvee seen sshhoowwnn in PFC tthhaatt PPFFCCss aarree production work er s, uaannbddiqaaurrieteonnuoostt iaangghee-u-ddmeepapenenndbdelneotno.td., aTTthhceeoeenssctteiimnmtaarttaeetdidonhhasallmff--lluiicvvheessoloofwf PPerFFtOOhSaSnaasnneddenPPFFinOOPAAFCiinn humans is on the production workers, humans is on the ooisrrddTeiekrroeolfyfstseehvvereroraaullgayyheeaanrrss..uTThhmoeefsspbooauurtrcecheewaoorfyfesexxpiponocssluuurrdeeinttgoo fPPoFFoCdC.swiianntetthrhe,e gguesenenoeerrfaalcloppnoosppuuulmlaaettriioopnnrioissudunuccntlcsel,eaaorrr,,obbtuuhtter eeoisfnnvvlwiiiikrrleoodlnnlyimmfteheenrntfotaraulolgmpphaaaattrhhnowwuuaanmyydsbs.t.ehrePPoFFwfoCCprslsadthh.haawvTvaeehyaaesllssihonoicgbblheueeeedsnnitnffgcoooufunoncnoedddnt,iinrnwatttahhiteeeornbb,sllouohosoaeddvoeaafnnbddceoeitninsssssouuubmeessseoerrofvpfvervaodardriiuinoocbuutsass,lsdsoppreeeaoccgitihleeessesr and mink in the of wildlife from and mink in the Midwestern U.S. around the world. Midwestern U.S. PFOS has been shownto bioconcentrae in fish The highest concentrations have been observed PFOS has been shown to bioconcentrate in fish. in bald eagles TTcoaoxnxiihccoaolvloeoggaiidccvaaellrrrseeesseeeafafrrcecchhtsoonnonPPFFthCCessliiissveoornngagonoidinngog.t.heAArnnoirimmgaaalnlse,exxappnoodssuuhrraees ttcooaPuPsFFeCCdsstaahte hhdiieggahhthccooonfntcceeesnntttrraaanttiiioomnnassls c(o(cfacynyPnnhFooamOmvoAoellgagoduuvvsesermmrolsoeonnnkekgefefydyeuscsr))tastffioooorrnnrrsteehaahessaolosinnvbsseerttehhanaanttsdaahroroeetwhnnneoortttoeernncgtataiiunrrseesell,yycaccnallndeecaahrer.ar.siEEcnxxaspupoosomsesuedurrtteehesetttohdaheiniaiggtmhhhaloccsoof,nntceaceslenttnthatrornaauittgmiihooannlsss oagfaPiFnOthAe omveecrhalonnigsmdsuarraetionnosthclaesarb.eeDnesvheolwopnmteontcaaluseeffceacntscehraivnesaolmsoebteesetnaonbismearlvse,dalitnhothuegh aoofgfffassippnrritinhngegomoffeppcrrheeaggnnniasanmnttsrraaatrsse exposed to PFCs, not clear. Developmental exposed to PFCs. e.ffects have also been observed in the TG`Trhhoeevppeootfteeancntitliiiaatlly iicmmappnaanccotttss booennfppuuulblblyliiaccsshheeeasalslttehhd ffbrryoomM m ppeerraffD lltuuotorhroioscctH hhieemmmeii,ccaabllecrreeallueesaaesseetssheffrrroeomamrtcthhneeot33MsMuf--fiCCcooitetttnaatggee Genrvoivreonfamceinltitaylcdaantnaoatvabielafubllleyraesgsaersdsiendg bPyFMC DimHpaactttshifsrtoimmteh,ebfeaccaiulistey tihnesreila,regrnooutndsuwafftiecrie,nt esisnuunvrrveffiasurtccoieengmwawtaeaitntoeentrra,,tl sasdekeadedtiiapmmleaaenvcneta.tsisl,,aUbaanlnneddderrbbeisigoottataara.nd.diniFFgnoogrrPtttFhhhCeiisscirrmoeenaaptssraooicnnbt,su, tMfMirooDDnmHHofthhhieaanssdfiarrvceeiiclcdoiuotmyamlmminseeonsnuoddriecel,eddsgottrhhfoaauttPnaaFdddCwddisaitttiiteooornn,taahlle einnvveisrtoignamteinotn itsakiemppolratcaen.t,Ugnidveernsttahnedliancgk tohfeicnofnotrrmiabtuitoionnavoafiilnadbliveiadbuoaultsohuorwcetsheofgPenFeCraslto the ptpeoonoxpvpiuiuclriloatantytiimobonaensniietssdieesoxxinppmooapssneeoiddrmtaattonlotPsP,tFFguCdCivissee,s,n.tththheeMellDoloannHcggkhwhoaiallflflf-i-nclliiofffoneetrmioonffautPPeioFFtnCCossawvioinanrihkhlauubwmmliaetanhnasbst,,ohaaeunntMddhPotthwhCeeAiitrrhpapeonotgdteeennn3tetiMiraaalltloffoorr tiionnxvveiecssitttiiyggaabttaeesaaendnddoaansssaseenssisms PPalFFCsCturrdeeilleeesaa.sseeMss fDfrroHommwttihhlele c33oMMnti--nCCuoeotttttoaaggweeoGGrrkroowvveeithffaatcchiileliittMyy..PCA and 3M to 11.. PPuurrppoossee The manufacture and disposal of PFCs at the site has resulied in documented contamination of tgTghrrheooeuuamnnddjdaawwncaueatnfteeatrrcMtaauittsrtteshhieaesnsssidtiptee.dp.iispPRPoiootvsteeeannrlttioriaaefllmPaccFiooCnnntsstaaatmmotibitnnheaaettiiisnooivntneeosofthifsagssoaotirieelld,s.uaalnntddeWodaofsiftsnesuudwrraofftcaaeuccrmeesewwcnaaotttneeetdrraicaanonninddntgassmeePddiFiinmCmaesteinnowttnessroiiennf twddheiieslsclcashhd,aajrraaggnceededdnitttnooMttthhihesewesairrstiisvveieeprrr.p.siuPPRpFFpiCvClyessrhshrayaevsvmeteaebbimneeseesnnetorddvbeeitenteegiscntttveheededsfitianincgimmaluittuelydtl.ti.ippTlW leeheaoosnnMt--eisswinittnaeeetemmsroosontnicaitotoPnoortrlaiinlinnuggtiniaaognnnddPCFpporrCnootsddruuwoclcettriieoonn aAwAcgtegeilevlnnsic,tciyyaens((;dMMbiPPnecCCtahAAue)s)weSSoauuftppeoeertrrshffuueuprnnpddclyoPPnrrstooyaggsmrrtiaeanmmmathhsiaeaosrsnvbbiineesgeseunntehsooevvtefehraerscseieslieeittiieynn.wggaTsssiihteeoeriiiMnngvviienensasntlteiilgsgyoaaatttiaidoodPnneodaalnnltuddoticctollhneeeaaCPnneuourpnpmtraonlent aLiLicnisvtsitetvsooitftPfiiregPisaro;tiriobioretnictisiaeeasusn,s,detthhroeeefsssoptttaaohttneeesreSScuuaopcpnetetirraoffmnuusnnindduanLLtdiiioesstnrt,, aiiisnncsuo11ne99ss88e5t5.nh.te o33srMiMdteehrhwaawassisbtboheereetinnghieccnooMannlPlddyuCucacAtdtiidnnseggidnvvctaaeorriittohohuuetssPtiemrem. anTehnet eM iMnnPvvPeiCCsrAtAoinsgmtsaatetaifnofftfnarsrleeaqqmnuuodeenssirttteeeosddpriotthhnnaagsttecMMoanDcDdtiIuHocntrrseeevduviineaedtwwetrhssiaeitteesctoddenoo,sccaeuunnmmtdeeoninrtndtssfeorpprrrwmeeaippttahairroetenhddeavttoMoaiddPlaaaCtebeAl,,ettsohhienencrrtecehssetuuhltlatotstsxitooicmffitey. The of ePPrneFEvcCCiosrsmoamanennmndddettnahhtteaeiiliromnbbseeohhnraaievtvgoiiaroorirrndigiinnncgttohhpneeodteeeunnncvtvtiieiarrdloonanpmtumbteehlnniettcsiiihnnteeaoo,lrratddnheedrrimtitonopfaddoceertvmvseealfltooripoponmccooatnnvhceaclilsuluiasscbii.oloennssonaanntdhde toxicity of recommendations regarding potential public health impacts from the site. 5 22000099..00000066 I1I.. BBaacckkggrroouunndd aanndd HHiissttoorryy "oTTnhheeap33pMMroCCxioommmaptpaealnnyyy8((6ff5oorrammcerererllsyyiM MnitinhnnenecesisototyotaafM MiCionntiitnnagggaaennGddroM Mvaean,nuufMafiacnctntueursroiintnagg.CCooTmmhpepaanfnayyc)i)liootppyeerhraaatsteebsseaaenffaaiccniilliittyy oopneraaptpiroonxisminacteely194876.5 aTchreessoinutthheeasctiteyrnofpoCrotittoanogeftGhreovper,oM peirntnyehsaostab.eeTnheusfeadcilfiotrya vhaarsibeeteynoifn roiinenpfddeluuresascttttrriiioivaanell oosrpiopneaecrdreaatst1iiiog9onnn4ss7m.ssauutTccehhhaerasissoattuhlhateesnhd,emmaaafsnontuerufrrfanaeccsptetouuarrrrteecioohonfafonaaddfdhthdheeeessviipvevrleeoopppprermooredtdynuuctchtotassfs,, sbiinienmddeiuunlsstautrrrsiipeaalrdloppfdoooulrclyytammseve(rarBsrsa,i,eratraynn1ddo9f91). "arTetThhfteleheifcfsaatcicaviinlleiidttryyooataalhdlsesoorsi3giinnMcnmlufaadccteielsliratiaaiupelpsse.e,rdrmamTinethdittetsfeeodrdrehhmraeaazszieaanarrddrdecoorhuuossafnwwtdahasedsttepeevreiionnlpocceipirnnmteeyrreaahnttetoosrrobfuuessseeeimndd tiutloosatertrdrpeerafaototdrwwuracaestsctstreee(ssaBtggaieeronrnnee1arr9naa9tdtee1dd). fGafaatrrrtomhmviiiesnnggaC,,nodoerrsonsithimmaetpnrpldel3yytMhrlleeefffatt3ciiMinnlitaaCiehnnseaa.tmtuuoTrrlaahilletssertteaaCtmteeen..atienTTrdh.heeerTssoihittfeeethhhleoaacsspabrtboieeopeenennrotkkyfnntohohwawesnnsbivvteeaaerrniiisoousuushssellodyywfanaossrittnrhheeeFcir33geMuMartieCCoon1ot.ttataaangngdede. ttsGhhyreesotssvieiettmeeCfllaeoarynyototeuhurtetaiivnssadsrsihhtohoouewwsn3nbMoounniCaahlrredeemcciaeeonntnltitttgheaaesreCiriefaaanllctiepplrhhi.tooytt;ToothhiienenlFFbouicigiaglutudiroier2nne2g.o. nfNNutohmotebteeesrittthsheaaftitso33rsMMthhoueuwssaenersseianaasFnndiuuigsmmucbrbueeesrsri1ie,nndaggnind this report system for this report arethe are shown in Figure 2, various buildings at shown in Figure 2. the facility; the building numbers for the areas discussed in PaPeemrrmffloluunooirrouoccmhheepmmeriifcclaaullossr((oPPoFFcCtCsas)n),c,apptrreiimm(aAarPriiFllyOy)pp,eerraffslluwuoeorlroloooaccsttaalnneoosisicceraaaccmiiddou((nPPtFFsOOofAAr))eaalnnaddteoodnnPeeFooCff iiptssrossdaalulttcsst,,s daademperprmiirvvooeexdndiimuffarmrotomempleyppreef1rrl9uffll4ouu7roootrroohocorotcocatutnaagonnhaeetasseunull(fefAbloPnencyyFtllOrffo)ll,cuuhaooesrrmiiwiddceeeal(l(lPPalOOsoSuSlFreFis))nseahhrtaaivvaoeemnbbopeeureenonntcsemmsoasafnnkuruefnlfaoaactwctetnduurraPeesFddtCaahttepthrShoeiedmsosuiincttsete.sssiinnccee p`aprAproolpcecrexeosasxsnsidm((eArAatbb2eee0ly0aa1nn1;dd9O4NN7EaagCtgahDasrsoeeu,2,0g011h299)8a8.2n2;;e3GGleiMilcllltviriloolalacnunhnddetmaaarnniiddclayMMlacfanelnoadduseerelildn1a1p99tri99oo33dn;;ucpOOtrloilssoceenennsosecfttkPaanlFloCw11s99n99a88ta;;st33hthMeMesiS11ei99m99i99nosan2;;s002 (aA(EtEloReRmxGGsan22cd00oe0m0r4p4;l2;e033t0MeM1l;y22O00r0E0e0p0Cala)Da.)c.e2PP0teeh0rre2ff)lhl.uyuodo3rrrMoooccghhveeeonmmliuaicnctaatolalmssrsilaaytrrheecateaacaaclsrleaeadsstssypoporfiofcodaorulrglcgaytainnoaiintcctoacccfhhhPeeemmFditCicocsaoalrlasstgatiihnnneiwwcshhiithieccyhhdinrffoll2uuc0ooa0rrri2ibnneoe:n `maimtnooohmlelecrsceeunuctlloelemyss ((sp3tl3aeMbMtlee2l2,y000n0r1oealnp)arl.)ea.acceBBteitehcvceeaa,uuhssayeenddoroofftrgtheheene vavseteorrimyytoshhsdiitegghgthhartssaaattdrrraeeentnntiggytottphhnicoo(aftf3llthMyheea1ctc9taa9arr9cbb)hoo.ennd--ffTtllohuueooorrrPiignnFaeenCibsbcoomnhnadyd,nd,urPPfoFFacCcCatsrsburoaarrcneed b`biyncyhom33eprMMaenniaattletystt,hhseetianssbicilttleeeu,dwwnieoenrrngeerseuutaasscieentdidvirieenn,peaaalnvlvdeaanrrrtiiesetst(iyyssotuoafcnfhctcoaotmosmmSdemcerogectrricacaidhalagltaiaaornndnddTMi(n)i3nd,Mudssutusr1rtif9raai9alc9tlpaaprn)r.toosd,TduuhfccietrtsesPbrFbyeyCtas33rMmdMaanaatnnnsuddfaaonoctdtthhueerrred fire-fighting foams, and other chemical products. companies, including stain repellents (such as ScotchgardXVt), fire-fighting foams, and other chemical products_ surfactants, fire retardants and "TPTOhhSeeFPP,OOaSlSFonppgrroowdduuccitatiioomntnixpptrruhoorcceeeossssfbtthyhrprorouuoggdhhuceetlleseccattrnroodcchwheeammsiticceaapll rffllooouudrrsiinnoaatftiiovoannryyiiaieeblllddess caaobbmoopuuo!t.s3i3t55i%%o-n-44(003%%M Pb11aO99t99Sc99hF0a;,;par33olMoMcnesg22s00w00(0i063tb)hM.)a.20mPP0FFi0xOcOtu;AArEeaaPnonAddf bi2ity0ssp02ssr)aaol.ldttssucaVatorrsleaatttynyidpplieiwccawaalalsllsytyteepppsrrrooaoddnduuduccceebtddyspoiirnnfoaadvuasscriiitmmasibillwlaaeerrrcffeoaamssvhhepiinoootnnseidtttihhotrronooutu(gh3gehhMaa abatthtamemtcoPohssFppphChreoerpcreree,o,sdsaaunnc(3ddtMissooon2mm0peer0o0bbccyye;ppsrErsooPwddAeuucrct2etss0a0wwt2ete)rir. eemeVrrseeo--dluuiasssteieplddeosiiwenndattshhiteeenasmmnaaannnoudnuf-bfasaycicttpteuruorpridiinn,uggcotpprsrrlwooaccteeeersrsessi..vnecW Winnateeasrsdtatteeteodtta.atrrhsse ffrroomm tW `RhiWevaaessPrtt.FeewwCaAatlpteterrorhssdouuccgoocnhtnitwtoaaaniisnnptiinernogwgcaPPetFsFesCCrswfsfrerfroroeommmatthooteippmeesreriaastttiiidosoinsnrpssoouaasttteettddhheeitnhssiriattoneeuohhgnahavv-aseeintbbeoeenpee-innsti, tddoeiirsswcclaahhstaaetrrrgegewiendadctittenoorettrhrhaezeteaMMdti.msiesssniitssssiippppii Rppclhliaavennmettipr.crpairAiloorlrsttthtaooobdiuldigiisthsycc.hwhaOaarrnsggteeeeowttoofattttehhhreeefirrbiovvymeeprrr,t,ohmdmeuaacsnnittyyseoPPfisFFtrCChosesutaaeprrdreeotrrdheeursscoiitssuittgaoahnnnttoatonfo PottrnOree-SasatFitmtmeieewnntptaebsbrteefecclwaauuuaostsreeeoroooctfrftteathahneteemiirrent cssaulhusllefofmoobnniecaatatpeelrs((otPPdaFFubOOcileSiStd)y),,.bwywOhhtinihcceehhosiiufssbthususeesuuqbaualyelllpnyytrorrcedehssueiicssmtttisaacnnoattlftttooohreffuueprrnttrhzohyeedmrruaddcteteiiggocrrnaahddoyaadfttriPioooOlnnySsniFnisttihsoheefpeeePrnnOfvSvliuFirr.ooornnomm3oecneMttna.ten.setIIittmccaaatnned tatthhhlsaaeottwddbauuesrrtpiiennrsgogdgPPeuOOnceeSSrdFFatbppeyrrdootwhddueeucrcstetuiioboinnnsetaaqthtuettehhfneeotiirrrcmhDDoeefecmscaalitctuiuarrld,,oAAwrlaleaasnbtbzeaaysmmma(aaippnticrrcioondhdeuyurcdcatttriieooodlonnyrsppdillsiaansontptf,,oPaasOppeppSdrrFoo.ixxnii3mlmMaaatnteeedllsfyytiiml99l00a9s%t%e)%d,ooff toohffetthhweeawwstaeassstteegssenwweeerrareetedddiiswsccehhraaerrggineeddthaaess wastewater, and 1% form of solid wastes wastewater, and 1% in the formof air missions (3M 20030). (incinerated or disposed in landfills), 9% in the form of air emissions (3M 2003b). 66 22000099..00000077 Geology/Hydrogeology `GToTfhehseeoaln33odMgM,y/CgCHrooatytvttdeaarlggoleegyeGGsorarlnooodvvg,ee7affnaadcciillgiirttayyveiissl uutnnedrdererarlclaeaiidnnepbboyysiffitillsll ammsaastoteecrriiiaaatllsesdaanwniddtuuhnntcchooennsasodoljliaiddceaantteteddMigglslaascicisiaasllipddpeeippoossiittss oRRmiofivvrseeaerrn..tdhTT,ahhgneera2ttv0hhe0iiclclkfkyenneesetassnassotdof,tfhaettnhhdseeossgueetradhdveeepreponlostseieitnrtssrdarrcoaaefntnggdheeeessposffrstroieotmsmaanaasdppsipporrcooitxaxhitieemmdasattwtreeelilatyyhm.22t-h00ceuftfeaeredeatjvaiiincnnettenhhsteeaMnnloooisrnrsttghihstwwsheieepssptetiattsootern maannoddrewwetehsstatenerr2nn0bb0oorfrdedeeertrssaotfotfththeheesoppurrtoohppeeerrrnyty.e.ndIInnottfhhteeherraasvviiitenneeassn,, dtthhieen upper bedrock the stream-cut upper bedrock formations have been ravines along the eastern formations have been ppaarrttiiaallllyy oorr ccoommppleletteellyy rreemmoovveeddbbyy eerroossiioonn.. `BBceeonnmeepaaottshhedtthoheefggdllaaoccliioaamlliddteeeppo(osasimittsas,g, nttheheseiffuiirrmss.ttrbbieecddhrroofccokk:rmffooofrrmmlaiatmteiiosotnnoniise)tth.hee PPTrrhaaeiirriiueeppddeuurCCphhoirieetnnioFFnooofrrmtmahatetiiooPnnr,,arie cdBdoeuunmCCephahoitieeshenndthhheaoassfsdiaatobb,uluontnmhddeaiatnnbetet(dssaroolomluuctatkiigoohnnnaesscciaabuvveimiteti-ineersisuc,,phbbliufuofterttmdhheeoollfonoawlwimeseerrerpsipetooosorrnttifeoo)fnn.auttTelehntnesddssaun(tpo0dpebboreenplmmyooortrtriheeoenmmlaooaswssfesitrivhv,eee.m.Porraeirie BmJmoaearsnsdsseaiianvvteehSapptnhoodrerstttsiiooiotnnnee,.ootfthfethGhrebeoePPudrnrraaodiicwrrkiiaeethddeauurs gCCbehehnieieeenrnnauliiplsslyippfdrrteeeossdeeesnnot.nnt.otaTTfshheleeroiwePPsrrraaeoiiarrfdiiifecalyuddulutfsrCCoahhnmiideetnnhoeFnFmlooyrormmrthaeaettimilooaonnswsooeivrvv,eeerm,rlliboiearssseatthlhee JPPBorreaarindirreaiianeetddShuuatnhCCdehhsitJioeeonnnredii.annnttGooSrttaohhnueednsJJdtooowrrnddaeaat,nenrtSShgaaeennsnddhsesatrtlaooelnnlyeye,,1d.eeoxxeLccseaepnwptort tewwnfhhlceoeerwreefrottehrhameedarrieteliyaaorrnfeeroaffcmrrtaascctahttusuerree@mssooo"rrrceossnmooflliauunsttisiinioovgnnel,ccaaabyvveairtsiti"aieless.. "ttBhThhaaetetniciennrahhotishibbsit-ithtssseectthJthoeierodddnaooinwwnnnSFwwaiangarudrrdsdetomm3niiegig,rlrlatauhttseiitoorsnanhoteoafslfgetgyrhroeoSuugtn.endLodwlawaowatgrteyeerrnuctnoedettfhrholeerymuuinnnadgtdieeotrrnhlleyyaiiscninttgegs. FaFsrraaanncc"ocononiniaafiSnSaiannndgdsstltaooynneee.r." The cross-section in Figure 3 illustrates the geology underlying the site. T"eTdwwgoaesddoeefeetpplhlyye iisnintcce.iisseeIddnggtlleaaccriimaalel nrritivveesrrtrvveaalalllmeesyyrssurrnuunnthffrrroooummghnnotorhretthhvattloolessyoosuu.tthhEaarllooosnniggontthhaeeleoeanasgsttetehrrnensaaennsddtrwweeeassmtteerrnn eccstdhhuagadnneynsneebollyssf tMhhhoaaessssscciltrreeeer.aatt2Ieend0dt0ess3rttme)eeeipipttnerrdanaivvctiiasntnteeersessaotomhnnesttphrhureeenssstooehunurtctohheoueeagfashsttataahsnneeddivessasoololuuefttyhhfswwa.euelsEstttrsosssoiidirdoeiensesnooatflefodttnhnhgoeertffthaahceciesilaleiitstyyst.t.sreoAAaumtrrheewcceeensnttt istnutdhiysbpyorMtioosnsioefr W(a2s0h0i3n)gitnodnicCatoeusntthye, pwrietshenacsseoocifaatesdermieisnoorf ffaauullttss oorriieenntteedd nnoorrtthhweeasstt--ssoouutthhewasets.t AinpathiirsopforitniotenrsoefcW tinagshfainulgttson Creopuonrttye,dlwyitphreassesnotcibaetneedamthintohr fsaituelt(sseoeriFeingteurden4o).rthAwnealsty-ssiosutohfeast. Attvhehreeptssaieecirafflaaouuofllttifnsstyfyessr-ttsoeeesmncmttsesihnbtbegyyffaBBauaualrlrttrrssoEEinsnngtgriehinpneeoeeer3rtreiiMndnglgpyr((opBBparaeerrrrsr,et, yn22t(00b00se33en))eFssaiuutgghguggrteehesset5t)sss. ittthTehehe(rreseeenemmoaFaryytighbbuweereesuut4pp-)s.t1oo0Au55tn00haefflaeyescesttitsoorfoefnfding vfaeurltticoanl othffe-ssietteoanpptheearfsatuoltcsonotnrtohle t3hMe lporcoatpieorntoyf(tsehee Fsitgrueraem5v)a.lTlehye inotrhthewsoeustt-hseoausttherenasptotrrteinodninogf ftthaheuelsstiiotteen,, twwhhheeersrieetetthaheepprraeavavriinsneetottuucrronnnsstraaobblrruuthpptetllylyosscooautuittohhneeaaossfttbtbheeeffosortrreeeaddmiissccvhhaaalrrleggyiinniggn tttoohetthhseeoMMuithsissesiaisssstseiipprnppiipRRoirivvteieorr.n. of Ts"Tuhhreefasscuuerrffaaanccdeeogofefnttehhreealgglrryooufuonnlddlowwwaastteetrrh,,eoorsruwrwaftazetceerrtttoaapbbolleeg,r, arrpaahnnygg.eessTffhrreoommw6a6t0e0rttoota11bl00e00 iffseeeefttoubbneedllooiwwn ttthhheee ggglrraoocuuiannldd dFsdueoeprrpfomoasascitiettissaonnnneedafaurgrrettthnhheeeerrrraiiflvvlryeeorr,mf,oiitlnnlhottehwhreeisvJJetoohr.rreddasaTunnhrefSSaaagcnnreddostsu~itnopodnonweegartnnaeeeparahrryitt.nhhTteehherreiivvvweaerrraitbboelluruusfftafffsb,o,lreaamnnaidsdtifiioonnnuttsnhhdeeisiPPnirrnaatthircreirieecgoddlnanuuceisCCathlheiidee.nn Fapannuoddmrmpiisisaneteisgsossneewnenftltuiilarastllhlloyeynr-oosfnnireoteem)uunniittish.t.etoTrTwihvhaeeerrd.nnsooTtrrhmhmeaealMlgiggrsorrsouoiunsusndniddwpwwpaaitatetRereirrivneffrllto.howewGvddriaiorrreueioccntutdiisowonanfot(Greicm.re..amtwwoiohdhneeeslnniisnnnoogitntbtiieynnrffcBllouaurneernnncec(ece2ddt0e0dbb3yy) S`psuugugrgmgogeupesnistndtsswgattwthheeeerlfflfasaouulolllttnsso-wsaasinntedda)sffirirstaactmcotituwugrrraeearsstdeiisnsnttththoheiiwssMaaarrirdseesaatishmmseaiapryyipviehhrRaa.vviveeTeshsro.eommGmeeordoiinneufflnlluduiewednnacctneeeorootnnmsptothehdceeeilfppiiaancttgahhlwwblayyayyesBv.saalrrua(t2e003) gffitaaruuolliluttksnseldeoywnnfattlhtheoeewrs33foMpMlalroppawrlroolseppleaertsrottyyitt,,hmhheoiogfwwareuaelvtvteeesrrratociittew.wwaoorudulltddhebbeerieevxxeppr.eeccTtteehdde ttmhhaaottdooennlccdeeidggrnrooouutnnsddpwweacatitfeeircraeelnnlytteererssvatthlhueeaffteaauullttss,, iHtolwikeevleyrf,logwrosupnadrwaallteelrtofltohwe fbaeunletattrhacteh.e sit s heavily influenced by the facility's high-capacity 20pHpr0rooo2wdd,uuecc3vtteMiiroo,nnrgewwrpeoeloullrlsnts.de. wd SSapootuemmmrepefilooonffwgtthhjbeeuesssnteeeowwaveteehllrlltsshoerrneeesppioboterirlttlieesiddohllnyyegahhavaalivvllyoeenibbsnoeeffeleunweaiinntnceeoorpdpeefrbrrayatottiimhooentnhfsseaiincpncircleoeitdtytuhh'cseethi11oi99gn44hw00se-s.lc.laspIIannocnity 2002, 3M reported pumping just over one billion gallons of water from the production wells on 7 22000099..00000088 ttthhheee papqrruooippfeeerrrttsyy b((eDDnNeNaRRth220t00h03e3))s.i.te.IInn pprreevviioouuss yyeeaarrss,, aann eevveenn llaarrggeerr aammoouunnttooffwwataerwwtaassppeuummprpeedd ffrroomm the aquifers beneath the site. IIfnnroffaamccttt,,hemmodosestvtoeoflfottphheeedggprroooruutinnoddnwwaoafttteehrreffrrsoiomtmc,bbaeepnnpeeeaaattrhhsttthhoeebmmeaajcjoaorpritittuyyroeofdf tbthhyeet88h6e655a--caatccirroeenoisfitteet,,haaennpddreeossdppuecectciiiaaollnllyy wsfwireotelelmllsdsetaahvsseeslsdhohepoovewwednnlofpiionnredFF3iMpgi.ourrgteTio6h6une((orEEsfoRReuthGGrece22so00i0tf0e44)t, .)ha.eppTTmhehoiadisrseslffti,iogguaubrnreeedcsitsahpfeftrruodormaemtdaaaabppnyaadsstthtaeggsrrsaooucuumtinnpodtdnwiwaooantftseetrhruempmoopondrdoewedllhuiffcooctrrihottnhihtee wwksiantaesos wdccnerreveaawetthleeoeddpt,,ehwdweerefrroteehr enn3ooMmtt e.aavvlTaaihilleiaanbbscloloeeurrpaactoterttahhoteefettdtihimpemueemmttphohiiidssendldg,ooeaccfnuufdmmeetcehntnettfdwwraaoatmass awwnrridittttaeesnns..umFFpoortrioeenxxsaammuppploleen,, wiitthiisiscnnhootitt the numerous nearby residential wwk"enTelohlllewsssneoorrfwaiichnnteccotllrhuuseddmreedadthyggeaeefmooflelooocdggteiitclchifefneecaapottauruprtreeohssrwsaasutuyeccdohhfpaaugssmrttohhpueeinndiignwntaeeetrfrfsesecreccctfttsliinofnrgwgo,ffmaabuuutltlhttessirrnieeusccmeelinnekttrellolyyyuisitddhneeannettatiimrffboiiesyedtdreiginnsriottdhhueiinnssdtaaiarreelaa,. wwpToaarhttteeeisrroetnthhfamaattcatmmyoiridgsgirrmsaacttaheeyassrabbgfeeefnnetcecoaattttthhhheetthhMpeeiastssshiiitweessaisiyspccpoaaifppRgttiuurvorreeeurddn. dbbwyOynatthteheeereffxfaalcocceiwiplliit,ttiyybounpptrraooitpddpuiuseccatltriiikosoenn{lyw0webtlehellalststhamaennosddosutootngnhlrleyyoausaanstdesmmranla.lll pmampooopsrstetitaopprnootrmrottiiabooyenndwooiifsfttcthhhhieeanrsstgiihettee,t,cowwathphhteeeurrrMeee SSizsiiosttneiessessoiDDfpI1tphiaaeRnnddipvrDDeor22d. uaacOrrteenieolldoneccxwaaectteleedlpdst((iaosseenneedabbtpeehplleooewgaw)rr.)so.utonTTdhbhwieisastthaaerrereeaasboeddunooteeheassetanhnsootttethrins- arca likely discharges to the Mississippi River. appear to be within the capture zone of the production area likely discharges to the Mississippi River. wells and the groundwater beneath this AAonssessmhhioolwweonnfootnnheFFiigg3uuMrreep7r7,o, ptthehreetrreyeabaroreeunaadppapprryroo.xxiimmMaoatsteetllyypri11v00a00tepprraiinvvdaattepeuwwbalaittceerrwessluulppspplliyyntwwheeellllassrelloaoccfaaottreeddwhwwiiictthhhiitnnhere oiifssnlgogeweemsoollipoolreggiiiomccafriitnihnlffeoyor3rtmmMoaattthpiieoroonnspoaaeuvvrtatahyii-llsaabobboulluteenhaaedraraeesrtycc.ootmmoMpwplaolerestdtteeptddhreiiivnnMatitthesheesaiJJnsoodsrriddppaapunniblSRSiicaavnnweddrses,tltlooisnneaien.p.ptheBBaeeerccasaareuutahssaeeftoggnrrroowouuphrnniiddcvwhwaatattehteeeorrrre pcfpluouobnbwltliiasccmpiwwrnaiamattneeatrrrisssluyuopuptprpolclyeythawwereeelsalolsl.ssutoohnn-sttohhueethnneoorartsthth tssoiiwddeearoodffttthhheee river re located in areas downgradient of Mississippi River, it appears that no private river are located in areas downgradient of or contaminant source areas. ``STuhSpeeiurnfvupensdetSiiSgrtaitteefiHoHiunsitsanotnorddryy.remediation activities conducted at the ste under the MPCA Superfund pTpMrrhPooegCgrirAnaamvmaesnhhtdaaigvv3aeetMiggoee(nnneMearPrnaadlClllAryyemcc1ee9enn9dtt8eie)arr.teeidodTnaharreaooscuuetinnvaddictttitieeevnsnitcwwioeaasns,stdteweuhcdditiiecssdhppooawsstaeatlrlheeaarrcseeoiaatnessdouourrnciitdggeieinndraatlulhllneyydM eiidrdPeeannCtctiAioffniieSseddeunpbbteyyrofttrhuhdeneedr csMsiiuggPrnneCeendAdtlbbayeenttndwwegee3oeeMtnniat(thtMhieenPMMgCaPPAnCCa1AAd9d9aa8enn)ndd.d33uTMMmhetiisonnet11ah99ce88ti5e5vx,,iitwswieteeisrrn,eegwnnchoootintcshffeoonwcctuuessoreeerdddceooornnntdhPPuaFFtcCCtswes.id.luTTnfhhodeeceurMMsaPoPcnCCoAAtnhseaeannnddt o33rMdMeraarree 2ciin0un0vvr4ere)ess.tntiitgglTyaathtniieooenngexoooitffisatPPteFiFnnCcgCesaoiinnfntaaahdllledwmmeaenseddtdiueiamadaaitttsotpthhtoheseassliiettxeeairs((cDtDianaasvgv(iincddootDDnosaouleulgnogltflaaoswsr,h,dieMMrcPPthChCawAAte,w,reppileelrrrefssloooacnntuaealsdl octcoonommPtmhFmueCnuinciactaitioonn,, om2mfa0atn0nhu4ufe)wfa.acacTtstuhutrereeede))ixswwipsaaotsessnaaaclpperraoiirmmfeaaathrsryyearwrreeeaaasssshtooeonnwdttnihshepeionsssiiFattieelgwawuraraeessas8aa.dd(nddToeehtddeayttloolaottrhhfeeewassshttaaifcttoeehllSSwouuwepspr:eeerrffrueulnnaddtelldissttt..o TPThFheCe llooccaattiioonnss of the waste disposal areas are shown in Figure g. They are as follows: SS"TiihtteiesDDsI:iIt:e wHHayydsdruroosffellduuootrroiiccneAAutccriiaddliNNzeeeuuthrtyradalrlioizzfaalttuiiooornnicPPiiattcid tas (containing unspecified fluoroshemical bycTpporrhnooicddsruuseccitttteess apwainntaddsohrhuyysvdedardurolofttfol,luubnoouerrtiuictcthriaaasclciiizhddea))shwwyinitodthhtrolblfiielmumeeoen..rcicoNNneaefucuitirrtdrmaaeltladiir.zzsaatt(Tiicoohonnenwtwtaaaairnssimnttahhgtooeuuurgnigahshltptsettcooi itfhhihaaeevvdeefplbbiuteeoeewrnneorcddehooennnmeeeviiicennarala bydcdpiorirroneeccccetrtsellysytewsspeaaimrmteppollraeenvddaalaauynnlztdd,edbaannutaatolltydhyezzisteeeddhraffmsooirrnnPeoPEtFifCtCbSehs;e;enyiinncsswottneeafaiddremahhhyyeadddrrz.roaofTrflldhuueooeourrtisiaccrwaamaccsiiatddteettraaairsrassldsfferirfoniomnmthetdtehhepueniPPtdFCFweCrerfpeperrdnooeeddrvuaulcectrtaiionodnn pstsattraraottmceeaertrseeesggruwiulalaealtrtieiiootnasnsens.la.flywTTzarresaadccceetoonccsoodinnedctceeeenrrnmtetrdriatantoteiibooiennfssnthoooenffy-mmhweaetzetaaarlerlssdaowwuheesarr.zeeariiAdddleeonntuthtsiioffwiuieegaddhstiiePnn FatthCsheesdttewaaferrissnr,,eebbdduuetuttnttehdhceeetrenndfeeeuuidtntreraartalhlieilzzaeenddd tar material itself was considered to be non-hazardous. Although PFCs were detected in the 8 22000099..00000099 PggrrEooCuunncddowwnataattmeeirrniianntitthohiniss.aarreeaa,, ssiittee DDI1 hhaass nnoott bbeeeenn ffuullllyy cchhaarraacctteerriizzeedd aassttoo tthhee mmaagngitnudieotorreuexxtdteenentt ooff PFC contamination. SS"TiihtteiesDDa2r2:e:a SSwllauusddggueeseDDdiissfppoorosstaalhl SSdiiittseeposal of sediments and sludge dredged from on-site wastewater tstTrrleheuaiadsttgmamereeemnnaatttwpperooainnsaddlsus,s,feoaadunnnddfodmmreatlahyeyebvbadeteiuesudpppocsottaonolcffeooonfuutrrsreaaadtcciirrmoeenssesniinontssfisazinzneued.m. esLLlruaoadbbugooserrafadtltruooeorrdryyignaaeanndtaaelfldyyrosscimiossomoofpnfso-sausaimnmtepdplswlee(assiosntofecflwttuhahdeetienrg sslTillikukuededllggyyeebbmsyy-h-appotrrewoorediddauulcclfttoossowueonfrfdttlheheeleveePPvlasFFotCCefdsppecrrovooeddnruucacecltntiitovoronanltaipptorrinoolcsceeesoossrfs)g).na.unmSiScaaemmrcpooplumlesepssfoloouuffontrdthhisneea(tsseVlludOudCdcSggo)eem.aapnnToddhussinoosdiillsarbb(eeieannncehelaaautstdhhinnttohhgtee: been characterized with respect to PFCs. slndge showed lower levels of several volatile been characterized with respect to PFCs. organic compounds (VOCs). This area has not Site D3: Ash Disposal Area STihtee Dlo3c:atiAosnohfDtihsipsossiatleAwraesa investigated using ground-penetrating radar, and no evidence of waste materials was found. The location of this site was waste materials was found. investigated using ground-penetrating radar, and no evidence of S"STiihtteiessDDi4t4:e: wPPahhseeunnosoleliidccfWWoaraststhteeePPdiiittsposal ofa small process wastewater stream from Buildin7g foar Tpehriisosdoiteftwharseeusyeedarfso.r tThheedwisapsotseawlatoefrasstmreaallmpcrooncteasisnwedasptheewnoalteransdtrepaomssifbrolymfBorumialdlidneghy7defo.r Paart opoWfehfBriBiulouiedlildidotiifwnntagghsr22e6n6eewwyvaeearassrsfbb.ouuirilTmlttahlooelnnywttooianppsvoteefoswttfhiatightaseitsrediss,itttree,,ilat imlwimmaicstiotiinbnnetggaliiiinennefvfdieilldttprrthaahtteiainootnosnloooamffnewwdabaitptoeoedrsresttgihbhrrrlaoyoduuafggothhrimotthnhaoeeldfffeoohtrrhymmedeeerwr.appsiPit.ta.erst W wohuilled ihtawveasoncevceur frorramneadltdlyh,eincvoensstiigruactetdio,nitowf atshbbeluiie~ldviendgthovatersotmheesbitieodweogurladdasteirovneoafsthane wastes weeffoffeeuccldttiivvheeavcceaappopcprcreeuvvrreeenndtt,iinnaggndhhuuthmmeaancnoccnoosnnttrtuaaccctttiooornr mmoifiggtrhraaettiiboounnoilodffinaagnnyyovrreeemrmatahiienniisnnitgge contaminants would serve as contaminants. an SS"iTithteiesDDaS5r:e:a SSiosolaliiddcssonBBcururerntnePPipitittAAarrpeepaaroximately 10 feet deep and 350 feet in diameter. 3M used the pit tTtoooihlbbiysuusarmlnruedooagfffefis--smsapapetececcornippacrrlroo,eddtuepuclcapttsssittissacuuspcc,phhraoanaxssdiggmrlleaaassstisesn,,lsy.ttaa1ppT0eeh,,eferrubeububt brbdeneerire,,npgaadadwhnhaedesssi3iovv5cee0cssa,,fserrieaaotggnssian,,llppdyaaiappfemeurrc,e,ltewwerdoo.owod3id,tM,hffiiwubbaseeserrdtggleltaahssess,,pit oSasoorillelyvvaeensfntloustsu.d.ngdeTThthmheeeaaatperrrreeeiaaaslehh,naapcssleassosiifntnicwcceeas,sbbtaeeeneesdnn,rccesooslvviunedesrgr.eee,ddTawwhsieihtthhbaunssrdeenvvcieenirrngaadlelwrffsaee.seettoLoocfofciafwlisll.illo.envSSaeololilsiyllobfbfuooeVrrliiOennCdggsssw,ddirtrsihiulllclweehddaasiistnnetthhiiss atoreluaefnoe,unedthtyhlebpenrezseenne,cetiocfhwloarsoteetsh,yslleundeg,e,anadshmaentdhyclienndeercsh.loLroiwde lweevreelsdoetfeVctOeCd si,nssuecvheraasl soil tsoalmupelnees, ceothllyelbcteendzefnreo,mtrtihcehlboorroiengths:yltehneea, raenadwmasestuhbysleenqeuecnhtlloyrgidievwenereredgeulteacttoerdy icnlosseuvreerablystohiel MPCA. samples MPCA. collected from the borings; the area was subsequently given regulatory closure by the SSTihittieesDDa6r6:e:a AAicsctatiinvveeinAAacssthhivDDei,issMppPoosCsaAal-l pAAerrreemaaitted waste disposal area or boiler ash and incinerator rTehsiisduaerse.a iDsuaen tionaictstipveer,mMitPteCdAs-tpateursm, iitttehdaswnaosttebedeisnpionsvaelsatiregaatfeodrubnodielerrtahsehSaunpderifnucnindeprartoogrram. residues. Due to its permitted status, it has not been investigated under the Superfund program. S"SiTittheee DDh7i7:s:torPPyiiott fBBtuuhmrinisinnaggreAAarrieesaaunclear. Three borings advanced i this area did not encounter waste Tmahteerhiiasltso,ryanodf sthoiils saaremapliseuanncalleyasri.s iTdhreneotbdoertiencgts tahdevparnecseedncienotfhhiseaarveya dmiedtanlost oerncVoOuCnst.er waste materials, and soil sample analysis did not detect the presence of heavy metals or VOCs. SS"iTithteeisDDa8gr:e:aWWisaaslsottceeatDDeiidssppaoolsosaanllgAAtrhreeebaaluff leading down to the Mississippi River. A variety of cTohnisstraurectaiiosnlodecbarteisd aanlodnogththeer wbalustffelmeaatdeinrgiadlo,winnctloudthinegMnuismseisrsoipupsidRruivmesr,. wAerveardiiestpyoosefd here by construction debris and other waste materials, including numerous drums, were disposed here by 99 22000099..00001100 ddinuuvmmoplpivinneggd ttthhheeemrmeoomvvoeevrraltthhoeefaeepddpggreeoooxfiftmthhaeetebblluuyfff.2.00AAndnrIIunnmtteserriaimnmdRRdeemrmeudemdicaiaallrcAAaccsttsiieoosnn(((rIoIRtRtMMed))daarttuSmSisit)tee. DDST8he dddinrrrvuuuommmlssvsewswdehertorheeweedddriiessmnppoooossvVeeaOddlCiiosnnf,ttahhpbeeuptoornonp-x-ossilimiytteceaht33leMolMyri2iinnn0acct0iiennddeerrrbuaaitmtoporshr..eannAyAdlsccdoo(rmmuPpmpCoosEcsi)aittreecwaesssarasmmeepspfllo(eeruonootdftfeattdhtheederlssuoeoimvillastbb)ee.ednnTeelaaehvtteehhlstt.hhee A cdcnooorumtmmpkposnosoissitwhteeonwissfaaesmdmapmpnllpoeeolVoeffOsttChwheees,rwwebaausasttnteepaolmmylayzateeteehdrrliiofaaorllrissnlaiiunnteottrdhhoeebchiddperrhmuueimmcnsasyllccssoo.(nnPttaCaDiiBnnueesdd) owvvtaaehrrreiieooeufuoxssutVVnrdOeOmCCaeststeaoalennpvoddagPPtreCCadBpBhslsey..voeIfltsS.iiisstAe nDoS,t knnootwalnloifftshame pwlaesstweserweeraenarleymzoevdefdo,r aflnudortohcehsetme iwcaalss.coDveureetdo athnde erexptrleamnteedt.~pography of Site D8, not all of the wastes were removed, and the site was covered and replanted. Boiler Ash Fil Area: BT"fiTohrheiiislsefaairrgrAeheatasihinissgFllipooleclcraaAsttroeeenddan."ooelnn atthnheed wwfeeossttteeerrsnntieenddgggfeeirooef-ffttihhgeehtffiaanccgiillpiirttyyo,,duiinnctaasnn(aasrrceeeaaFttihhgaauttrieiss 8uu).sseeddBoffioolrretrrraaaiisnnhiinnfggrooomnn--assiittee fciciloorlaealli-f-nfifgiitrrhheeitddsinbabgoroiepilaleeerrr(s,,Boauunrssnreeedd1l9ttao9on1pdp).rrofoodSdruouticelcesbtssionttregeiaanmfmgifrsfeood-rfrrihhgieeheaatdtitnaaignnndpdtrhvoivsaadrruaiircooetuusassi(snsihdneuodeswutFesritdigraiulatrlhpeepbr8orooi)c.lceeesBrsssoeeisssl,e,hrwfwalaaslssh1uufssroeebdmed. ffaoorr ftaaihpplelpprribnoooxxitilhimemirsaataateserlhelywyaaoo(Bsnneeeuxrffrpooo1oot9ts9eiin1nd)tt.hhaitiScctkokhinneleebsgssosr,,roiuaannnngddds sttdhuhrreeifvlavloecoeldl.uuimmnLeetahbwwiosarasaasrteeeoassrttyisimhmaoaanwtateeleddydsaaittsh88eo55fba00occisluueabbrmiiapccslyyheaarfordidfslls.s.tuorSSfbooaemcmeee of of twnwhiaeactkteeberrlo,tithlhaeaanrttdahhsvaahaddnwppaaodosiooullemeex.ddpoii nTstehthhdeeeaaaatsrrthcehaaewassgshhrooodwuwenetededdrseemullierenfvvaeaacdtteeet.ddo Llbleeaevvbeenollossrnaoo-tfohframmyzeaetartanadllaossl,u,yssii,ninsccallonuudfddaiitnnhsggeamaaanrnpettliaiemmwoooanfnsyys,u,croaafrvrasseceerenneiidcc,, wnwiiicttkhheccl,lleeaaannndffviillallnaaanndddiuvvmeegg.eetTtaathteeedd.a.sh was determined to be non-hazardous, and the area was covered AAIdncerOrvyclltiicocbAdeecriiddoRfRel1e9lee7aa3s,see3AAMrreedaa:i:scovered that approximately 17.000 gallonsof acrylic acid had been "IrrneTehlleOeeaacUssteSeoddbTeffrrtrohoomamtf awa1nn9a7suu3nnt,dhd3eeeMrrsggorrduooirusuccnneooddfvsstettrhooerredaaggtrheeealttteaaananspkkep(w(rUoaUxsSSiTTma))baalltoeonccldyaaottnee1ded7d,aa0ddi0jnj0aac1cg9eea8nn6lttl.ottnooTsBBhouiufisillaaddcriirneynaggliwc77aa((scBBiaiudrnrrvrhea11sdt99i99bg11ea))et..ned Tbyhe3MU,STantdhantowfausrtthheer saocutircone woafsthreerqeulieraesdebwyatsheabMaPndCoAnebdecinau1s9e86t.heTahcrisylairceaacwidaswainsvtehsotiuggahttedto hbhayavv3eeMdde,eggarnraadddeneddo naturally further action naturally. was required by the MPCA because the acrylic acid was thought to ArPA`AesrearsastsaotooeffdPPpFdFrCCevuiPoruocsdluy,cttPioFinCaanpnodrdoUUdnsusceetion began (on a pilot scale) atthe site round 1947; full-scale `AcbcoesomgmsammtnaeteriercndciitapahllreePPv1FF9io6OO0uAsAs.lypp,rrTooPhddFeuuCmccattpiiiorononndarrueercppetoaoirorfttnoeerddbllPeyygFabbCneeggp(raaoonnnduiiannctp11ii99lo7o7n6t,6..ssctaPPolOOreaS)SgFeaF.,t-dtdaehenrerdiisvvtieeteeddstacicrnhhogeeummwniadiccsaa1lcl9epp4nrr7too;eddrfuueucdcltlt-iiasoorcnnoaulend bBBwueauigsilalddpniihnnianggsssethd77e,,ou1115l59,,6a0t11s66t.,,haeaTnnehddn2ed25m5o,,afwiwhn2i0hac0ir2che.haaarfWroeearsssPthhFeoosCwwfnnprriioonnmdFFutiichgetguiouPrnerE,e22Cst((poEErrRaoRgdGGuec,22ta00in00o4dn4).)tp.ersoTTtichnheeegssppwrrwaooesddruuceccetdtniiitooesnnrpoeoodfsfeaPPdrFFoiCCunsnsd wSwSiaiattsesetpDeDwhI1aatsaaeenndrddtoppruooetssassatiitmbbetllhnyyetSSpeiilnttaedenDDtobSef8..f2o0W W0ra2eas.stdteiW eswwcaahatsatetererrgsssetfccroooomnntathaiteihnneriiinnvPgegFr.PCPFFSpCClrssuoddwwgueeecrrteefiorrrnooomuupttrteeohddceettwhshasrrosowtuuegegwrhheatttdhehieerspootnorn-es-seasiitdttmeeiennt wplaasnttewwaastedritsrepaostmedenatt opnlaentt ibmeefoirneSdiiescDh2a.rgePFtoCthceonrtivaienr.inSglfuidregefifgrhotmingthcehewmaisctaelwsawteerrtereaaltsmo ent tpelsatnetdwoanstdhiespwoessetdsiadteoonfetthime efaicniliStiyteinDt2h.eaPrFeCa ocfonBtuaiilndinigngfi4r3e. fighting chemicals were also tested on the west side of the facility in the area of Building 43. tI1nhne220w00a01s,1t,tetwhhaeetcechhreetmmrieiccaatalmlsesenetwweperlrlainlitnnewesserrrueunnunnpiignnrggadffrerodommanvvdaarrriioeoupulssaccchheedemm(iiEccaRallGpp2rr0oo0dd3uu)c.cttiiooEnnxcaaarrveeaaatssiooofnftthohfee tsshiteteeotltood Stspheeiewpweewesrrawpspetiierppweeessaactaoetrrtrthhtoreedeneanodtromtratehnhnedeatahspsatltdaccnooltrerwannkeeeerrdr.eooffuTpBBhguuieriallddsdoiieinndlggs1ai1n55ndt((hrtteehhpeeblaaPPcsFFeeCCdan(ppEdrrooRsddGiuudcce2ttwi0iaoo0lnn3l)spp.lloaafEnntxtt))hcearreveevvaxeetciaaaollveneaddtoittfhohtanahttehttahohdeelda pssVttiOrproeoCnnssggwpp(ehrhreieencnohcollolioirccrroooocdddteoohdrer..naenAAd(TcchCooamEmdp)ploeoasansikidtteeed1.ss,aa1Tm-mdhppilelceehsoloofoiflrtsothheieenthstsahiindedeee)bwwaaaaslnleldl asspnoihdilelnsssoihhldooiewcwweecaddollmsllpoooowwufntllhdeeevsve.eellxssc3ooafMfvmmaeateitlotsaanollssh,,ad a VreOmCosv(etradichpolortroioenthoefntehe(iTnCteEr)ioarnfdlo1o,r1f-driocmhlotrhoeenthoartnhee)aastndcoprhneenroolficBuciolmdipnogun1d5s.in3rMespaolsnose to removed a portion of the interior floor from the 10northeast corner of Building 15 in response to 10 22000099..00001111 concems over possible damage othe buildin foundation from lees ofhdfc acid. concerns over possible damage to the building foundation from releases of hydrofluoric acid. Soil samples were cllcted rom borings placed around th inci tench: Anlyss of he sil Soil samples were collected from borings placed around the interior trench. Analysis of the soil Sampls Showed very low levels of mat, nd ons seve sompound {oo bl ppshahtmthhapallaleatsete)s).h. oTTwhheeedaavccettirivvyiittliioeewss rrleeellvaaettelesddottfoomtthheeetasslees,wweaenrrdrreeoppnlleaaccseeemmmeeinn-tvtoiilnnataainnleddcaaorromouupnnoddunBBduuii(llbdduiintnyggl 1b155eniiznnyddiliccaattee: hat release tothe soil (and possibly roundvater)of hemicals ued nth PFC production that releases to the soil (and possibly groundwater) of chemicals used in the PFC production proces did accu whit the PFC productionplan was in operation No analyses for PFC process did occur while the PFC production plant was in operation. No analyses for PFCs themselves were conducted however 50 is not clea If PFCs ae prsent insol and themselves were conducted, however, so it is not clear if PFCs are present in soil and roumdvate i Building 15 groundwater at Building 15. 101991,anai dispersion model was developed or VOC and inorganic emissions tthe M - In 1991, an air dispersion model was developed for VOC and inorganic emissions at the 3M Cottage Grove acy Pace 1991 The emission points modeled eluded wo 4b-o0t Stacks at Cottage Grove facility (Pace 1991). The emission points modeled included two 48-foot stacks at Dulin 15, the PFC production plant hee ydrogen fuori emissions aceure. The Building 15, the PFC production plant, where hydrogen fluoride emissions occurred. The `eemmiissssiioonn rraattee uusseedd iinn tthhee mmooddeell wwaass 00..3388 ppoouunnddssooff hhyyddrrooggeenn fflluuoorriiddee ppeerr hhoouurrooffooppeerraattiioonn,, Wiha stack exit vlosity of 14D fot pa mina t ambient (10F) emperais. Toe host with a stack exit velocity of 1,440 feet per minute at ambient (70 F) temperature. The horizontal ent and he cmt concentrationsofhydrogen aoe (si the 1956 amma verge nd extent and the estimated concentrations of hydrogen fluoride (both the 1986 annual average and The second Highest 34-hour erage in microgram pe cubic mete) predicted by he model re the second highest 24-hour average in micrograms per cubic meter) predicted by the model are Shown Figures 9 and 3 The rel fthe sie dispersion mode ict hat hydrogen shown in Figures 9a and 9b. The results of the air dispersion model indicate that hydrogen Horde smsions axtended off i n 1986 fluoride emissions cxtcnded off-site in 1986. "TaTthhmeeoPPsFEpChCeprprerooaddsuuccmtteiiorotnnipporrnooeccdeesspssrewwvoioouuulslddlyla.lsso3hMhaavevestrrieemssauutllettdeeddthniantt thhLee55rree0lleepaaossueenoodffssosoofmmPee OPPFAECCscottoomptthoheeunds waeetraemreseoeserpsehlleeoardssece,sadarsrttoemdthehbneettiiaowirneeefFrdnoopm1r0eve0veni(ont0ut2sss0ltaya0c.ckkas3syMastpethehserteimCCyaooottraetadg(gte3eh1aGGtr2ro1o0v0,v90ee500)fF.apcloiPluirytnyedssniunmoa11fb99Pl99Fy77.,O, ataAnnddlcaothshmitatptsottohhumenedsof trwSwhheeieeelresreeaPPshFFppeOerrsOooAAyoddcuucccoccouoeemrmdmr.p,epodhhohauaubennnneddddvtllwaeeerrddeeie,le,oenaoouasrss1euuos0sssp0etterodt.ao.tthh2oFFe0nuua0gsaigii,idrttaiiSwwvyvueeeescreheapemmeffirrisosoyrssmemiiauoorBnnBnss(uu3oiiioMlfldfndiPPni2gFFng0O0O.110AA55ce,,)((0.osbrorotPtnetrhhoeerasvvSruaabaymppmyooparbblrbuiulnaynlinlgd,ddd.iainnpptagagalnesrrsdtaiiwwsccrthuuhieslleaornirtmeeeeg))ePPwwFFoeCCefrsrsee aooTplppsedeorrraaoltitgkiioooennnlyssTf((ar33orMmMde22t,h00e00n00vc0da).r.iohTTeuthhseeobppphyheeSryaivsticiicoaaonllsapp,nrrsoocupepceehrrrttaiisleessdosorfuPfmPFoFtlOoOhaAAedinaaagnntadd, rraoeettahceeetrrolrPPyFsFaCCm0sspadarlirdifenfigedf,riefa5frneder4enrdntrtysffirnrogomm hHHnyododwwr5oeegvrees,nrg, fgthlhueeeotiraiittdrheGad,tiiaspPpneFedrrOstshiiAooeninerimmboseodihdeaoelvlnirrsoeers(suobulnotstcsheffooprrerlahheyyarsdderrldoogegteeonnathnffelduuoaovriarriipddaoeerreeeplmmhiikaisessssleyii)ootnnfossodssmihfhfootbwwrhnnaBsiiunnaiFFrleiidgsgiuuunrlrtee.s1s559.a and 9b suggest that PFOA emissions (both particulate and vapor phase) from the Building 15 rCemassmoanysiasoyhaavles ehxatveendoecdcuofrtehde site property. Deposition of PFOAfo he sil from these area may also have extended offthe site property. Deposition of PFOA to the soil from these emissions may also have occurred. OOSnniS-eSititieenvGGersrootuiungndadwtwiaotanetrearctMoinvoiintteitsroitrinntg~hsaannsddieUUbssoeega,a est21 permanent mitring wels have ben Since investigation activities at the site began, at least 21 permanent monitoring wells have been idennsiteerdsa,t aannd aurowuenl tahme bteer,o edevpatlhu,ataengdrgoeunnedrwaaltceartqiuoalnistys(rFi2gurfeol1l0o)w.s The monitoring wel installed at and around the site to evaluate groundwater quality (Figure 10). The monitoring well identifiers, unique well numbers, depth, and general locations are as follows: [wan |yom Ther | Monitoring Well Gener Location Well ID [tw mse | a0 Noremsie ondary MW-1 Eas sideofsie 1 MW-2 0 Centro sic MW-3 Unique Well Number 233567 233568 233569 Depth (feeO 200 192 210 11 Monitoring Well General Location Northern site boundary East side of site Center of site 22000099..00001122 [CMMWW-4 T253253375700 1 220000 |SSoouuth-hce-ntcraleamrearoaf sliteareaofsie| MW-5 233571 210 Northwest comer of site MW-6 233572 Norbess comofeirc MW-7 233573 [MW MW-8 T3527 3354 74 MW-9 233575 27 Southeast arenof ste MW-IO 233554 [E Cowaz|asosi | E MW-11 233950 Sout ge of sie MW-12 233951 Soutien aren oie sr ponds | MW-13 MW-14 233952 442211770055 219 West-central area of site 146 Northeast corner of site [171373 |SSoouutthhwweessttaarreeaaooffssiittee | 104 West-central area of site 237 Southeast area of site 200 Southeast area of site 126 Southern edge of site 126 Southeast area of site, near ponds | 6600 | DD88 AArrceaa,, ssoouutthheerrnn eeddggeeofosfistitee,, nneeaarr PPW W--66 [MWoM MiW W--61156 | 31238| 140 431237 186 431238 140 |Sowhemedgeofsic Southern edge of site Southern edge of site | [MWe [7025[91 |Wesccenmlarrorate| MW-17 MW-18 570322 570323 112 West-central area of site 91 West-central area of site MW-19 [MWoiOT 630685 | 100 |DIArs,southeastcomerofsie | MW-IO1 [owei0 | so6ss 96 TDIAressoutheastcomer sie | MW-102 612713 680685 680686 62 West-central area of site 100 D1 Area, southeast corner of site 96 D 1 Area, southeast corner of site Since the facility opened in 1947 3M has installed sgh production wells 0 sre the fuciy's Since the facility opened in 1947, 3M has installed eight production wells to serve the facility's otal water Supply and provid wae or vaiows dil opraons (gr 10). Thy ae potable water supply and to provide water for various industrial operations (Figure 10). They are iollows: as follows: T Cine Bue Dep | CasingDiameter WelllD Unique Date Depth Casing Diameter Well Number Completed (feet) (inches) al Hise 1017 ww PW-1 231867 1947 205 20 ww ase [ew|e 0] [ PPPWW W---3[ 32 ms22e 3311886689 1948 Tse 1956 | 202 20 222a4 [1616 | [w[a ew v om[i e e] PW-4 231870 1958 275 16 PW-5 231871 c. 1960s 113 24 Ps 117 1070 15 3 PW-6 229117 1970 143 24 PT PW-7 233576 c. 1980s 200 Unk. -- PW-8 424131 1986 208 8 FFoouurroofftthhee eeiigghhtt pprroodduuccttiioonn wweellllss ((PPWW--22 ttoo PPWW--55)) sseerrvvee tthhee ppoottaabbllee wwaatteerr ddiissttrriibbuuttiioonn ssyysstteemm,, teens is eo 2 ese bas for ve sapptat (PW md a oe while two wells are used on a periodic basis for fire suppression (PW-1) and to supply nonContact Coomgwie 11h Sh wists ninror (W-61 ERG 2009 OF he remain two contact cooling water to the 3M waste incinerator (PW-6; ERG 2004). Of the remaining two ell, PW-7 sd oxasoally ate ose ap range and PU. suppl de guard wells, PW-7 is used occasionally at the 3M on-site trap range and PW-8 supplies the guard poshack. Inthe ast low Ives ofVOCs including TCE, 1.1 2-ichroshae, |.I-dihlorothane, In the past, low levels of VOCs including TCE, 1,1,2-trichloroethane, 1,1-dichloroethane, etybanzen. vere and meyers chr Have bo dled in erious momar 410 ethylbenzene, toluene, and methylene chloride have been detected in various monitoring and `pprroodduuccttiioonn wweellllss aatt tthhee ssoouutthheerrnn eennddofotf thhee ffaacciilliittyy,, ssppeecciiffiiccaallllyy MMWW-4-4,, MMWW-1-144,, PPWW--55,, aanndd PPWW-- 212 22000099..00001133 e66,,xcwwehheiidccehhdaahrreeealllotocchaa-ttbeeaddseiidnn dtthrheienvvkiiiccniignniiwttyaytooeffrDDcSr8.i.terLLieeavveienllsstohofeiftnhtdheiesvsieeduVVaOOlCCmssonhhiaatvvoeerioonnngllywyeoolcclccsaa,ssiaioonnndaalltllhyye eddixissctterrieibdbuuettdiioohnneooaflftththh-eebaccsooenndttaadmmriiinnnkaainnnttgss suggests tha water criteria suggests that the sourcesofthe VOC contamination in the individual monitoring wells, and the sources of the VOC contamination aatrrhece lilonoccPaalWlii-zzSee,dd aoannndde nonofotttheeexxttweeennlssliisvveeth((aEtERaRrGGe 22u00s0e01dlaaf,,oErEtRRhGGe d22r00i00n1klbib)n).g. wTTahhteee.rccoosnuncpcepenlntytr.raahttiaioovnnessoroeffcieinnndtdiliyvviibddeuueaanll VlVeOsOCsCs.s ttaihnphapaPnlnWiaacppa-5bppl,rreoooxxrniieemmgaouatlfteaettlhloyyerooywnnoeeerllmmhsietiachclrratoothgga-rrrbaeaamsmuesppdeeedsrrtfllaointtredrrtahr((edluagsgd//LrfLi)no.).krainSSwguuacctwhhearcctooesnruncpcsepeunlnptytprralsaytyt,iisoohtnneassmv.eddoorTennhcooeettnseetylxxysccteebeeeemddenis less araretepggtphuulelilcaasattieebtddleeaadrnnoeddegsummolnaonotnitoitratoyoprroeepdrdehbbaeyyarolMMtbhDeD-bHHaashaaeussdmaasatppnauunbhbdlelaaiirclcdtwwhsaafctotoeernrrcasseuuwrppnappltaleyyt.r.hsiuEEspxxptpplioyomsseusu.yrrseetettomo .VVOOTCChses siinynsggterrmoouunnisddwwaatteerr at the site does not appear to be a human health concern at this time. PPM3EFMCCohMansoibneiettonrimonognariattttiothrheienSniSggtigteeroundwater, production wells, the water distribution system, and wD`3waMaatssathteeafwwsraaobttmeeerermnttorrnemeiaatottmonmrieetionnntrtgipnpwllgeaalnnglttsro,ceuffpffnrllduouwdecnunatcttteffiroo,orrnpPPrwFFoeCCdllsussc,((tppiaorrniinmdmwaatrrehiilelllyysw,aPPtthFFeeOOrSwSdiaaastnnterddridbPPuiFFtsitOOroiAAnb)u)styffisoootrnaeramsaynnrsuutemmembsbeh,erroawnoondff yyicenearrss. D`TTmaaaabbjtlaoleerfirt11o,y,wmwohfihmlitloheeeneeidtffaofftlrluaiuneesgnnfttwoddreaaltlPaasF,ffrOproroAmomdauttlhhcoeetnieoww,anasbswteteecewwallausats,teeearrnittidrrheteaahastetmmbweeenneatnttepptrllhdaaennistftt'oaracirrbueeuspptoirfroeienssneevsnneyttsseettddeimgiianntaTTiraoeabnbsllhaeecot22w.i.vniTTtiihhneees at tStmhhaeeamjpossliirtteieetsybbweeoeiifnrntgegheccaoondnnaadldtuayuczcietstdeefddofrobbryPyPb33'FOMMOASuu,annldPdoeeFnrrOe,aaAb,vveooacllnauuudnnttstheaarreyiyt4aha-gga,rsr-eeb,eeemmaeenennndttth7wwe-iicfttoahhrcbEuEosPPnAoApfe((ir3n3fMvlMeuso22tr00iog00s1a1ubtli)bof.)no. naaSStcooetmmisveeiatnieds at ostahmeprlaecsiwdse.reThanea4l-y,z5e-d, faonrdP6F-OcSa,rbPoFnOPAF,Casndwetrhee 4li-,ke6l-y, faonudnd7-icnartbheongrpoeurnflduwoartoesrulbfeocnaautesse atnhdey waoarreteehreepprrrceeaosscleeildnnetstc.tiinenTdtthhhoeeenl4PPy-F,FiC5Cn-,w2w0aaa0nss1tdt,ee6ss5-0tthchiaaatnrtwbfweoorenrmreeaPtFddiiCiossnsppoowossneeerddleoiinlnnigkssteeeelvvyreemrfraoatllurnaaedrrneedaiasnssoitonfhfettthhgheeerPossuFtitneCe.d.cwoMManutcuececrnhhtbreooacfftattiuhhoseenesddtaaihtnteaay w`grreooruuenndcdiowwlalaettceetrrediiss onnnoolttyyyieentt available. 2001, so information available. on long-term trends in the PFC concentrations in "The well monitoring results indicate that PFOS and PFOA are present in groundwater atthsite TiPinnhFtteOhhSeweDDeaIln1ldm/aaorroreenaaPit((FoMMrOiW WnAg--e11rx00ec1s1ueealatdnnsddtinhMMedWiWMc-aD1-t1e0H02t2h)H)aetaaaPnnlddFthOtthhBSeeaasDDneS8ddaaPV~rFa:eelaOau((AeMMsaWW(r-eH1-1pB44r,Ve,s)PPeWWnft-o-ri55nPaagFnnrOddoSuPPnWW ad-nw6d-)6a.)Pt.eFrLLOaeeAtvvteheillness sooiftfe tPhFeOseSwaenllds/,orsoPmFeOtAimeexscbeyead tfhaectMorDoHf 1H0e0aoltrhmBoraes.edTVhaeluHesB(VHBrVepsr)efsoerntPaFOleSvelanodfaPFcOonAtaimninant tihnedsreiwnkeilnlsg, wsaotmerettihmatesMbDyHa fcaocntsoirdeorfs1t0o0boersmafoeref.orThhuemHanBVcosnrseupmrpetseinotnaolveveearl oliffaetcimoen.taTmhienant HiHNnoBBdvVVreissnmkbwwieenerrgree2wd0d0eae2vtve;eernlleotohipptaeehtddeMrbbDyythHMMe DDcvaoHHlnusbebidsaasseteerhsddetmooosnnebrrleeevvsveaiisefewenwoofrooffrtaahhvevuaamtiiollaxaanibbcllcoeeolttonoogsxxiuicimccaoolplltiooinggopiinucctaaosllvwiienenrfrfoaoerrlmidmfeaeartttiiiimovonened.aabssTyoohfftehe NEPoAv.emTbheer 2H0B0V2;fnoeritPhFeOr Stheisv|alyuge/sLithtehme sHelBvVesfnoorrPthFeOtAoxiisc7oluogg/iLc.al TinhpeudtesrwivearteiodneorifvtehdebMy DthHe EHHhaPBBsAVnV.ostTffodohrreevtthHeheleBsoseVpeettdwfwoooHrcPcBooFmmVOppSofoouiursnntd1dhsselaaaognnt/dLhde;rttthhhpeeeieirrrHfttloBouxxVoiirccofoosolluorolggPfiioFccnaaOalltAbbeasaisssaiisns7dcclaaaagnnc/iLbbd.see,TffmoohauueinnndddleyiirnnivbAAaeptcpipaopeunesnneoddoififxxthae11.l. MaMMcDkDDHoHHf haavvaasaiinllaaobbtlldeeettvooexxliioccpooelloodggiHiccBaallViisnnfffooorrrmmtahatetiiooonnt.h. er perfluorosulfonates and acids, mainly because of a lack of DDtheeetteescoctutaatbhbellreen:lleeevvneeldlssoofoftfhPPeFFCCfssa((ciinnissoloonmimeettoyccpaaossfeessthsselliiggbhhlttlluyy;aaPbbooWvv-ee2ttahhteetHHheBBVnVSosr))thwweerernreeeaanlldssooofftfoohuuennddfaiicnni::liMMtyW:W-P-44W-aa4tt . tnhoertshowuetshteorfntehned moafithnefafcaicliiltiyt;y aonndtoinptohfetwhaetbelruiffs;tPiW bu-t2ioant tshyestneomrthitesrenlfenTdhoefstahmepflaeciflirtoym; PtW he -4 nd(dliioessrstttsrrhiibtwbhuueattsiniotonoonnfsseytyhsusetgte/emmLma)wiwnwaaasfssacccaooillllisllteoeycc;ftteaoedndudnffdrrionoimnmthMttehhWewe-cac7aatefferenttodeerrirtsiihtaareiaiibnsnutBBti(uuoaiinnlldddsiiyunnspggtre1a1m11d66ii..tesneAAtlf.vhveyeTrdryyrhoellgooeswaowlmlloepegvvileeecllaflrooolffymPP)FFtfhOOreAAom t(lheessmathiannfaocnileitlya.g/LN)owteasthaaltsoPFfoCundadtainaMreWno-t7anvoairtlhaeblaestf(oarnadlluopfgtrhaedmieonntithoyrdirnoggaenoldogpircoadlluyc)tiforonm twheellms aaitnthfaeciitliet.y. 3NMotheasthpartoPpFoCseddattao caorellneoctatavcaoiolradbilneaftoerdarllouonfdthoefmgroonuintodrwiantgearnsdampprloidnugctfiornom wallelolsftahtethaevasiiltea.ble3Mmonhiatsoprrionpgoasnedd ptorocdoulcleticot na wceololrsdiantattheedsrtoe.unTdhiosfwgoruolunddbweavteerrysahmelpplfinulg ifnrom ccahhllaaroraafcctttheeerriiazzviinangiglaPPbFFleCCmccooonnnttiaatommriiinnnagattiiaoonnnd iipnnroggdrrououucnntiddowwnaawtteeerrlalasccrarootsstshsetthhseeiteff.aaccTiilhliiittsyy..wToThuheledaabvveaaiivlleaabrbylleehddeaalpttaaful in 153 22000099..00001144 ipinnrddoiidccuaactttee,i,ohhnooowwreevdveiersrp,,ottshhaaalttpggrrraocotuuinncdedsww.aattTeehrriiisnn issneevtveeurrmaallsaarraeefaafssecootffintthgheethsseiitcewahhtaaessrbbweeeeelnnlsaaffsffeeerccvttieenddgbtbhyy ppafaasscttilPPiFtFyCC. production or disposal practices. This in turn is affecting the water wells serving the facility. cAAonggtrraoomuuinnnddawwtaeatdteergrrmmoouodndedelwl addteeevvreelliosoppleeidkdelbbyyyc33aMpMtuaarnneddd ffbooyuunntdhdeiipnnuttmhhpeeissniitgee aifcielteissonssuuoggfggetehsesttsspttrhhoaadttucmmtuuiccohnhowofeflttlhhseeat ottcfhhoeetnhtssaeiitmeea,,irnaeasasastesshdhhooogwwwrnonnuiiinnnndtFFwhiigagtuuferrireegui66sr,,el.iwwkiTeitthlhhyettchPhaeeFpCeetuxsxrccedeedeppttbieiyocotnntoehdofefitptnhhuteemheDDpIwi1nagaatnenarddctdDDiio22sntarroireebfauatsths,i,eollnpoorcscoaaydttseeutddcetjmjiuuolssntetnswsdooseuultstlhshuepeaapatsosttrt 1touonfdttthehhriiesslayccriooennnagcclscluuhasostiiawooannn,n, idaanllattthhshoseouuufmggipghhtuiiirtteoii.nsssTnohuotestePppdooFsisCsnsisiibbdtlleeecttoeoncestveetvardlauluciuntaaitttoheenettwhwheeeartvveeaarlnliiodddtiiisttatyyrviaoobifuftltathihbioilsnse mmsayoodstdteheeleml tbbileeemccneaaduutssshieessuttphhpeeort dudMionoscdcsuueimrmslesyeininpnttpgiwwdaRaasistvawwerrari,nitttdtceeinan.ts.hsruCCmodoinpnrttetaiacommtnilsiynnauoatrsteeepdddosggisnrrioobiutulsnnycddvowwianaatsttteerhrureciintininottthnheeerwmDDie1t1rteeAAnnrtrocestaatazmmvcoaaosimsltatibllilikekteehalleytyrtddhaiviesisnccteihh.maarreggteehssisttoo tthhee immediately north Mississippi River, immediately north of the either of the DI Area. directly or D 1 Area. possibly via the intermittent stream in the ravine "TpTrhhoeeceffsaascceisill.iittyy'B'ssotwwlaatetederrwddaiitssettrrriibhbuauttsiiobonneessnyysspttreeommviiidsseuudsseteodd effmoorpr lppoooyttaaebbellsee fwwoaratdteerrri,,naaknindngffoworar tvveaarrriifooouursssiionnmddueusstttririimaaell, phhtrrooeowwacteewevvasesterere,s,r.aaunBsdeoanadttlGGeiAdndACfCwoaotttrdreeeraparthtmeampseeannrbtatetsseiyynossnptteraemonmvdhhidcaaelssedbabnteeoueepnne.miinnpWsslattoaaslyltlleeeeeddwsaiiftnnoettrrhhdeefrrimmnoakamiiinnnthgcceaawsffeeeatttueeesrriisaafoiiirnsnscbboouumliillleeddciittninmeggde11i,6 n1t6oto wtvvraaaersraiittooeuwuwssaattsseeeerrwwuetesrhreesdsryyeissfntoterefmeomosscdo((nssptecraeeeipbbnaseerllPaootwFwioC))nsffooafrrnrdttorrmecealatetthmaemneeugnnrptto.iiunnW ntdthhaweesattooeennw-r-sasictitetoeerntwwfaramoasismtnteeatwwthaieatosteneer,ructarsnaeedatstmamisenenycnottPllFppelClcaatsnnettdp..iicTTnkhheeed up duringthe useofthe water wastewater therefore contains up during the use of the water for production PFCs from the for production or other purposes throughout the groundwater contamination, and or other purposes throughout the plant any PFCs plant. picked UUnnddeerr iitss ffeeddeerraall (MN0OO14S) the NNuaaettiinoontnaalfPProoollmlluuttthaaennttwaDDsiitsseccwhhaaatrreggree rEEclliaimmtiminneaantttiioolnnanSStyyssittseemmmon((iNNtPPoDrDeEEdSS)b)eppfeoerrrmmeiidttischarge to t(trhMheeesNtMMei0dsi0ss0esifi1ssf4ssli9iuppe)ppntitiheRRoirievvefefarlr.nu.aelSSnyistinnifsccreoefmo22r00t0P0h00Fe,,Ow33AaM.MstehhLwaiasmairtreteereggduutlrledaaraarlltaymy ecicsnooaltllvlpeaccliiatlecnaddtbli22se44m-b-hhaooconukuirtrtococr1ooe9mmdp9pbo6oesfsi(oitstreeeeessdTaaiammsbcpplhlleaeerss2og)oefftotthhee tLiLrneeevacveateelrldlssyooe2fff0fP0lPu0FFe.OOnAAtWfiohhtraahvvaneetghaegelnyepenshriesaarsalfeolllyryodPuedtFceOolcfliAinnP.eeFddLOsisAmiinnipcctreeeod1c1du99c9a96tt6a,i, oiwwsniiatnthvhalaaiannltaeboov2lvee0er0rba2alal,lcl kfhhliitgoughhe1noo9tff961c1,o.(9ns99ce91eeng~TttgrLa/aLbtldiedeoetn2tes)e.ccottfeedd PiP(nFGFeOAOaCAAr)lyaatnn2rdd0e0aPPt0Fm.OeOnW SSt ipsstlhhhaoontuuhtlleddatpcchtoohannestteiisnnotuuu(eet0tooorfeddPmrrFooopOp.v.Ae33poMMrrogaaadlnlussicoocticiionnonssntttiaanallllmeleiaddntaeaaln2alt0arsr0gg2(ee,inggecrfrlafaulnnuduuiellnnaagtrrcPaaoFccntCtiicsvve)aanttfeterdrdaotccimoaanrrtbhbseooonnf w(nWGoaatsAsettdCeeww)tahattartteeearrtttrmereeeeaanfttftmmlpeuelnenanttntftpplrlaaaotnnmtttheeeaffsffrlileutuegeeinntoottnabbreleefmfwooraoresvedteidesoiwscracghthaaearnrrgigcteercetfoaoontmttthaehemnetMiMnipalsisnassnitistssss((iiitppnhppceiilEuRRadigiivvnleeergr.s.PPFIIottCissnshht)oofpuurlloladdmnaa,lltsshooe bbee noGoporpetoeerrvdaaettteehfddaactbbilyythittteyhheee(fsM MfcleeuetertFnroiotpgpuoforrloleiimtt2aa)nnamCCraeooguyunioncanlcisalilol)) wclloooanccstaatatteieewnddaleetseossrsweetnnlrteetiivaaaetllmlllsyyeonwwfititPpthhFliaiCnnnsttth(ahetshggehrarEoosuuabgnnedldeesssnooPfftfoothuihnneetdp33ilMMnanl-t-i,mCCioottetttdaaggee: studieast other wastewater rcatment plans in Grove facility (see Figure 2) may also contain studies at other wastewater treatment plants in the U.S. (sec low levels of the U.S. (see page 23). PFCs as has page 23). been found in limited FsForororummndsowtsattccehhreemmcioincctaaallms,i,anaeaertriiiaoalnl.ddeeppHoososiwittiieoornno,offgaaicvcoeonnntttaahmmeiipnnhaaynnstitciiasslnnpoorttottpyyeppriiicccaaslllyalanyadppeaantthvhiwwraaoyynmffeoonrrtal behavior OfgofarfoiPPluFtFniOOdcAwAsaiaatnennrddWecooosttnthhteeaVrrmiPrPigFEniaCCntsisiaoiintai.nissdHppAoooslwssasieibbbvlaelee.mr.,agAAaiirvicrreneseummtsihipsseesscipiotohennydsstsiooocffahlPPaFpFvrOeOoApAceoaanrtntnidred/is/booaurrntooedtdthhteeenorrvPPPirFFEoCCOnsmAs /aeatPnt tFpparrCloobddeuuhcctatiivooinnor cVfcaioocrnnigttliaaitnmmiieiaisnnaDaitnetiipoW otnn.oeoosftffsVsoEoiniilrvlgiaairnnnoiddangmgarernoonduutnAnPddrlwwaoabtateatecmertriafforanroromc2m0s0ttuh3hso;opsseDeecatffieaakdcciiilntlioitt2iih0eea0ss,v,4)ciin.ncaaoddnddtirititbiioounntcttdoo toootthhPeeFrrOrreAelle/ePaasFseeCss ((WWeesstt Virginia Dept. of Environment Protection 2003; Daikin 2004). sBBieteecc,aaiuunsseeDoeofcfetthmheebepprootte2en0nt0tii3aallMffooDrHppaassstttaafafirceeomlmliiesscsstiieoodnnsswa((taaennrdd sddaeempppooslsieitstiioofnnr))omoofffPoPuFFrOOpAArivt1oa0thehaarvveeesieedxexnttteeinnaddleewddeololffsf site, in December 2003 MDH staff collected 1 water samples from four private residential wells 14 22000099..00001155 lMTooDccaaHtteeddlajjubuosstrtaaetasosrttyo.offTtthhheee 33lMMoc-- aCCotottoitaafoggtenehesGGrrfooovvueer FrFaeacsciiildlieittnyytiffaolorwaaennlaalllsyysasiirss ffsoohrroPPwFFnOOiAA FaainngddurPEeFOO1, sSSlbboyynttghheewith the approximate extentof ir emissions of hydrofluoric cid predciedbythe 1991 ar model. MDH laboratory. The locations of the four residential wells are shown in Figure 11, along with the approximate extent of air emissions of hydrofluoric acid predicted by the 1991 air model. AAPVPliFElmllOiOcffAAsoo/uuo/PrrPfFwFwOeOe1l.SlS0llussgaa/aannrLraaeellayyrrsnseeiidllssaatts0siivh.hv5eoeollwwpyyeeLddddee.enenpopore((ddsaaeeppptteeeppcccrtrtotoiiivxxooeiinnlmmssya,atooteifefnllPPyyaFFn22OOy22AA00o.fffooteerrhceetPtPbFbRfeeOOolluSoSrowwwaaebbggloorrsavvad,deeee)tt.)hHh.eeowTTlleahahvbbeeeoorrrrreeaa,ssttuouohlrrltetyyssodadofebefttstteehehccenettciioeonnof wddliehemteteeitctchstteaaorbbfllsee1u.PrP0fFFa~OcOtgeAA/LdeooaprrnodPPsiFF0tOO.i5oSSn~iitangnn/ttLdhh,eesrueffbosospuucerracdduteieevcenepptlywnw,eielitlnllrssaantssayiamomonppfllhteehaddesddfooooceecususrrwnnreotedtl.lrrsee.ssToohHllevvoeewMttehDhveeeHqqr,uuleteahssbettoiiroaoabnntsoooerfnfycdeoocsf not have the ability to analyzefo the 4, S- o 6 carbon PFC at thi time. whether surface deposition and subsequent infiltration has occurred. The MDH not have the ability to analyze for the 4-, 5-, or 6- carbon PFCs at this time. laboratory does OrOSeinnpterOOeVcscteitnsooitbtbaeetrirv11e44s,,o22f00t00h33e MMMDPDCHHsAtsatSafufffpvevirsisiftiuteendd ttphhreeog33rMMam--.CCoMottPttaaCggAee GGsrtraoofvvfeeamffaaicnilgliyety,d, taahlleoonnsggewwviiittshhi orthe rppPeueuprrrrppfeoousscseeernootocaffhtibbevmeeeiccscoooammlfiistnnhg(gePaaMFccCqqPsuuC)aaiAiwnnettSreeudedpwmweiaritfnthuhunfttdahhceeptffruaaorccgieirlldiaittmyay,n.ldlaaMyysooePuudCtt,AaannnddsdtaaswfrefeheaaessrorreoafnfPgtthRheeedCfatwahacecsiltsilitetyse wwwvheihsereiretreefdoirspthoseed. pc33oeMMnrsfluffuaalcoctiiarlloniittctyyhfoeaamnnddtichcceaoolrasrpp(oocPrrFaaltCtees()ssttEwaaRffefGfrc)ceoomnnddauunccuttfeeaddctttuhhreeedssiitateendvviisuiis,te, dla,looannnggd with thei ead environmental where ?FC wastes were disposed. with their lead environmental consultant for the facility (ERG). TC"Tohhueen88t66y55R--aoacacrdre ss1ii9teeiniislColooctcatatategeedd jGjuurssottvsesoo,uutMthhinoonffetsthhoeetsni,ntteoernrssteecthtiiooMnnisooiffsUUiSSppHHiiigRgihhvwweraa.yy 66B11ecananuddseW Watashsehhisinniggctitsooann CcTcahhoceeiummlniititccyyaaliRl ppoullasaadnndtt1,f9iiotirniicsChaesomseteitcaccuguarerleeGmfaaracocniviulleitft,yyaMcwwtiinirttnheheaaseosffttuualil,llngopp,neerrptiihrmmeoedetMuteecrritsfesdeinesncsvcieeeplpaaoinnpddRmeiccvnootennr,t.traroBnolldleeecfddaoureensnttehtrreyty.h.ienTTcsihihtneeeeriastaion ofodfaehfcvahielzailztayoarprdidmsooeuunusstsedcc(hhRfeieovmmreicircchaOaelslmkwwasiacs)tsaetlesTms..oanTTtuhooefattshchoteeuutcerehaaas,sttteeoosfftttihtnhhegee,BfauparrclcoiildinlutgycttoaadnrreeNevaoerggltooohlplefmfrccneoonuuStrr,assnaeetnaaadnnFfddeorrrReetasshiiiedldreeinonntactidiiaanllmearaitnion dPVliioenniveenetaalnonpddplamtnththe,eenotMMpi(esRisrsisaivitssesesridibppOppyaiikRtRshi)i.evveeMrTr.e.ottrTThoooepttoshhloeeiuawwthneeasCrtoeasuarnrthectieaalB)rr,eeuggrailigiooninngacatlluolwnwuaaNsastloteerwwathanaetdtreenrrr atStrrlaeenaartttamemsFeiednenettnRptpaliliaaallnnrtotlaa((ndttdhh.eme EEaTaianoggllteehsse Pnooritnht apleanUt,Sop1e,rasteadtebryetdhehoMmeestr,opanodlitaanreCgioounnaclilp)a,rakg.ricultural and rural residential land. To the north are US 61, scattered homes, and a regional park. uThsheee, tssriiteteatvvimisesinittt,ffoooccuussdeeisddpooosnnatlthhaetfftoohllellosowtweii:nnggtaahrereafsisrebbeetccaaaiuunsisneegoofaftrthehaie,irrpraaossdssuooccctiiaiatotiinoonnwewwlilitsthhPPPWFF-CCSmmaanandnuufPafWac-ctt6uur,ree,, ttuMhhiseeses,PPitFsrFesCCiaptppmprrioeonRddiutu,vccetotriir,oodnnaisnaaprdreeoatas,h,aeltthhwaeeta stDDhtI1eewsllaaiattnneedd:rddtsihisseappoofmissraaeelltnaararreipenla,ai,nntttghheeaarrwweaaaas,sttpeerwwoadattueecrrtictorenaawtmmeelelnst plant PW-5 plant outfall ai the and PW-6, outfall at the Mississippi River, and the wastewater treatment plant area. "FFTiihrreee iTTrrraaiirnnaiininnggiAAnvgreeasar:ea located blow the main facility, near Buikfing 43 (Figure 2). Facility eTespmmhiplepll.lfooiyryeeieeetrrssaaiarinnrienartgrlaaaaiibrnnoeeeraddatishhoerelryroeecvaieitnnnetdfiirhrbeeoeoffldoiig,wghhotttrihniaegn mltthehaarriokoniuungfggahhcpivivlpaiaetrryliii,oonunue.sseammrPooBaccrukkiolssdfiiittnhuugaastti4ioo3anncss(,aF, issiguusuccurhhendaa2ess)r.laaFcciahhnceeimbmliiyticycaaall Hsggpraraaivlvvel,eeblla--ecfceioonrvveeeuirrpneegddaraccladoobenncdocrrrreaeetttloeeartyppiaavvddeelwwnytiirthethcoedodnrtdrlaa,yii.onnrss a3lleeMlaaeddasiiktnnaiggnffgttooipnaidpiliecialnnitenedded.hhtooPlhladdairitnntghogefpptaohorninedsda..awreTeTashheeiussaauerrndeeaadfeaoarrpplappfieaenacairrblssiytt1yoa0 ta esning purposes and 1 es ire suppressants containing PFCs (ERG 2004). have been upgraded relatively recently. 3M staff indicated that the arca was used staff training purposes and to test fire suppressants containing PFCs (ERG 2004). for facility PPTrhrooedsdueucctttiiwooonnpW WreoledlluslcstPPiW Won--Sw5elaalnnsddaPPrWe=l-:o6c:ated onth southern edge of the fcily, close 0 the Mississippi River (see These two production Mississippi River (see Figure 10). PW-S feeds nto the wells are located on the southern Figure 10). PW-5 feeds into the facility waterdistribution edge of the facility, close facility water distribution system, to the system, wwhhiillee 1155 22000099..00001166 dPPeW Wt-e-c66taiibsslooennlllyeyveuulssseeddofffooPrrFCnnsoo,nn--appnoodttaaabbmlloeencciootooollriiningnggwwweaaltteler lffooocrrattthheeed iianndccjiiannceereranatttoortr.o. PBBWoo-tth6h PP(WWM-W-5-51aa4nn)dd hPPaWWs--66 hhaavvee. decMlleWeot-vevcaa1ttt4eaedb.dlelleAevlvpeepevlalsserleoosnffotPPlfFFyPC,CFscs.Co.sn,sAAtarndduidicsstppaiooomssnaaolldnessibitittroeeirsi((nDaDgSn8)wd) ewwdlarlasuslmollscoooaccftaaewttdeeaddasdootjnneacttmhehaneettehhtriiolilllzPssliiWsddeew-6jjeuurss(etMt araWbbeoom-vvo1eev4e)PPdhWWaf-s-r66omaanntddhis loMhlcoialcWtlaist-ioi1odne4n.addunAurdripibnnpuggarritteehhndeetlsmymoi,imddc-e-o1t1n9i9s8m8t0re0sus.ci.ntio`TtThnhheeedpewwasbatasr.sitsteeTasshnhhedaadddmrarruieemnppooswrraottesefdtdwlleyysasbbiteeedeemnen naddttuuemrmiipafapleteisddDewSoodevvreeewrrerrttehehmeevoeeovdldeaggtdeeilfooerfofomttrhhgeeathniics. hcccooiolmmmlsppipldooeeuutnenadndasdsdd((biVVutOriOiCoeCnsda)sl);s;oPimtFt iCeistimnnmooonettikkitnnnootorhwiwennngipiaiffsnPtP.tFEhCTeChawweraeamsasttaoeeifssnPwwwWeea-rrse5eteppasrrneeiddsseeePnnnWttt-iafa6iss.edwweleallt.l.D833MMwehhraaess agreed volatile agreed toorganic to complete additional PFC monitoring in the area of PW-5 and PW-6. PPPFFECCCsPPwrrooedrdueucctptiirooonnduAAcrreeedaa:in Building 15 for many years; the plant has now been shut down and is to bPeFCdescwomemriespsrioodnuecde.d iPnFBCsuilwdeirneg u1s5efdoirnmtahenypryoedaurcst;itohneofpolatnhtehrasconmopwoubneedns sihnuBtudioldwinngasnd7, is16t,o baabunnerdddi2ee25dc5.o.smeTTwmhheeeirsssseeliiobbnnueuesiildltdd.hiianntPggFrssaCaansrreetwossethhrhoeoewwuonnns-eisidnnitiFFeniiggwthuuaersreetpe22r.wo.adtWWueacrastisttoterenessaoftffrmroeoomntmhtettphrhleeacssnotee.mppprrTooohccueeensssdsesseebssiunwwrBieecrurdeeisledddwiiinsescgcrhshaai7rrng,geee1sdd6,ttoo obhhpaauevvrnieeedss10iinsnetccwheeeebbgreereeloinnnuernrseedppthlslauaacrctfeeraddacneww.itiottThhthhaaeennreouunppa-grgserriaatneddueewmddeassrstyyoessuwttseeammstettrtahhctaakrttesaiiastsmnccdoeonnvntettaanpiitnlnsaeendditn.wwtihTitethhheiPinsnFeaCabccupoorrnniocecdrdrueectstteeeiwottrnererenanlcncihdnheusse aorpceans,toantdhe3gMrosutnafdfcsounrffaicrem. eTdhtehraet athreerneuwmeerreoauisr setmaicskssiaonndsovfecnhtesmiinctahlesP(FpCermpirtotdeudctbiyonthaend use MarPeaCsA, )anfdr3oMm tshteasfef sctoanckfsi.rmed that there were air emissions of chemicals (permitted by the MPCA) from these stacks. D"DTl1hisAArarereesaa: was used in the past forthe disposal of PEC production wastes. It is located on the top toTohffheaiastnnoaaaprorrerfraotowwwhaeppseepnuneisinnneisdsnuuslilunaaloatoh,ffetllhpaaenanddsltattfnhhodaarttdteehxxetrteednonisddfopssfossssphooaauulrttoshphelfeayaPssFtotCftfrrhopoemrmosdttohuhueectthrrioeetssnott wwooaftfarsthdhtseeest.ffhaaecIcitirllaiiistitylylro((ocFFaaiditggeauudnrredeon88))t..heFFrtrooopmm tMhiesstiospsiopfpitheRipveern.insTuolat,htehenolratnhdtdherolpasndofdfrsohpasrptolywatordtshea sroavuitnhet,otwharrodusghthwehriacilhrotahde wanasdtewater ttMmrroeeinasaitstmtimsoeesrninipttnpgppillwaaRenniltvtleoosruu.t(tffMaTalWloll-tss1httr0ere1eanamoamrntrrdhuunntMshs.W.e-lAA1annn0odo2tth)dhererofrdlpiadssnisktpopotwoshsaeaalrlDdIsssiittadeei,,rsaDDpv2o2i.sn,iaeils, tillhtooercc.oaauttegeTddhhjejuwusssehttwiwcweehsletlsthstoeohfwfaDvDaIes.1t.sewhTToawwwteonor tmheonhiitgohreinstg wleevelllsso(Mf WPF-1O0S1saonfdarMdeWte-c1t0e2d)atftlahnek sthite,Da1nddiasrpeolsoaclastietde.slTighhetsley wdoewllnshihlalvefrsohmowthne otDDfhI1ethahaerrieegspa.he.ensiAAtncclscecuovolreardldsoiirnnoggfinPttotoFhO3MeMS'sts'srsoeaccfmooa.nnrssuduleltttaaenncttt,e, dnnooatssteeheeeppsssiootefr, ssappnrrdiinnaggrssehhlaaovvceeatbbeedeeesnnlioogbbhsstleeyrrvvdeeoddwaanrrhooiuullnnddfrotthhmee tbbhaasesee. of the peninsula or in the stream. TW `WhaaesstoteeuwwtapatuteterorfTTrtreehaaettmwmaeesnntttePPwllaaatnnettrQOturueitfatatlml:ent plant is piped t an intermittent stream that uns through Tarhaevionuetpaultoonfgththeeweaasstteerwnaetedretorefatmtheenftacpillaitny.t is Tphiepeoduttpouatnenintetersrmthitetesnttrsetarmeatmhrtohuagthruanpsiptheroafuegrh aexriatviinngethaelosnmgaltlheestea(satnedrnlaesdt)getroefatthmeenftacpiolintyd.JuTstheweosuttpouftt heenteDr2s tahnedsDtr1eamantdhrdoiuspgohsaalpairpeeasa.fter eTTthxhhieisetrirpneeogiiisnsthtaaepwpeshemrermmnaalalnneneesecntnet(staseenafldrfyulul.eaensnTtt)thtmemraeosnantitrmtiteooearrnmiintneggpntoppenoordisinnjtatutstshhtmeeawrrleeelsaatpssoowwnfedeltlhlj.le.usDtSSt2tnoooarrrmnmtdhwwoaDatfte1etrrhlaeiinssrdaaallidssloiorsopddaoiidssscatchrlhaaaacrrrkggeseea,dds. aatt tphaisssepsoiunntdwerhetnhenreacielsrsoaardyt.raTchkebrsitrdegaem, aenndteernstearssmthaellMpiosnsidsjsuisptpinoRritvhero,fathsesrhaoilwrnoaidn tFriagcukrse, 2. pTTahhseesesssttrreueanamdmeriissthvveeerrryyaicclllreeoaaarrd,, and vegetation and small fish could be readily track bridge, and enters the Mississippi River, and vegetation and small fish could be readily ooabsbssseehrrovvweeddn iiinnn iFigure it. 2. `TWWhaaessttceeuwwraratetenetrrTwTrareseatatetmmweaentnettrPPltlaranentat::tment plant consists of various seting basins, biologic eatment Tvvweaehsssestseeeclsluss,,r,riaaennnnoddtrgwffaiialnlttsieetcrresswwtatoaosttehheraasnnt,rddelalaeentdmffooteuuhnrertoofipntflcathihnenetercffaioivtvnoeesriwwspatarsssototceeefsssvsttarrwreieaaoasmumtsssewsaaaetttttethlhriee)n.gffaacbcSiaitllsiioittrnyyms((,wssabaatinnoeiitltroaarrgiyysi,c,noootrtrregguaaastnnmuiiaccelnlyt wroaustteeds,tihnrooruggahntichewtarsetaetsm,eanntdptlhaent,inbcuitnecraantobreprion ctehsesewveanstteowfaatsepri)l. lSotroarmccwidaetnetralisrneoletausse.ualAlly the routed through the treatment plant, but can be in the event of a spill or accidental release. At the 1166 22000099..00001177 i dneindsdchooaffrttghheeetotttrreheaaettmmieenvntrt,pprraosocdceeesssstcthrhieebewwdaasasttbeeowwvaea.tteerr iiss ppiippeedd iinntot&oa sseerriieess ooff hhoollddiinngg ppoonnddss bbeeffoorree discharge to the river, as described above. 3W3aMMsthheaawssatcceoornnsrtsaruttcmtreeduntcaltolaaperreggrdeeatggirroaannnsuulalaanrrdaarcctetiimvvoaavtteeeddPccEaaCrrbsboofnnr(o(GmGAAtChCe))wttarreseatatetmwmaeetnntetrppltlaarnnetatt0tomeanatuuggpmmlaeennnttteitftfsslucnt. e"wTTxhahceesetseeesffwffoiaicfctie9iere9nnt%ccr.yeyoaotfmf"tTtehhheneetGGGoApAACeCCratftfroiooerantrrsememeamnnootdvvpirilnenamggntotthhvceeoenPPPsFFFiCsCCtss foffrfrrooom1mm8 tttlhhhaeeergwwweaaGassstAtteeCwssttratetrreaermaattrmhheeaaanssttms0voeensfatasrrepllbbsaeenetethnnaetfiinfnalureentth.e efifiinxnnocaarellgsttasrrneieoacafttm9wma9ees%nnttet.sss.ttTeehppAeffoGosrruAbtthsCheeettccoreoofammttbhmbieiennnteertddepawwltaaamsnsetttneectosivntrersescisasaetmmslsssowfrfirool1l8mmblatethrhgeueessseaaGdnnAiisttpCaaerrcyytirfessiaeecwwtamelerler,y,ntofoorrvrggeaatsnnrsieieccaltswwitanhagssatttteehsase,r,eaatnnhdde iiWinnnioccliirhnngeetarhrnaaeittceooxrrwcw~aeavspstatetsisteoe.wnwoaAatfteesrtruhsbsettsreeleaatarmmog.ef.stthTTeohhnteeere,eeaxxwtimihssitteiicnnnhgtgvhtrarecessaastbtememlseeennwnttrilepplfoobunnreddbusisssraehredeedtstowpobeibceteifhaaiacbbasaalnnlydedoofonntreeddtreaalainntnddienrffgiaillntllhededed,,will be usd as a backup sorage pond When needed. with the exception of the largest one, which has be used as a backup storage pond when needed. been refurbished with a synthetic liner and will O`OfAfsfsf-nisotitteeeWdWaitnaetterhrUeU"sGseeeaoanlndodSgaSymaHmypdlprilionnlggogy" section, there are approximately 100 private and cAcfioosemmlnmdmeofrteoecrrdcitiaihanlel twCwhieeetlly"lssGofllCeooooccltaaotttgeeadydg/wwHeiiytGtdhhririononvloooenngieey"mmliosilceleeactotoiefodfntta,hhpeetphr33eoMrMexiappmrrraeootppeaeelprrypttyry1o.bbx5ooimumuninadldtaeearslyryyn..o1r0IIt0nnhwpaaedrddsidvititatiotioeoftnn.ah,nettdhh3ee Mwweellll 1fppiorreooltdppheeefrrostyyor,u,tthaahenneaddCstttihth,yeeaowwcefreloCllslosfftittieahelgeddeMffiGoosrrrtsotihhvseeseCiCipispityilyRooicofavfteeHHrda.asastptWipniargtnosegxirisismsllaaoomtccepaallttyeeedsd1.aaf5pprmppormrioolexfxsioiummnraoatrrteeetlhslyyiwdtteehhnsetetiosaslafamwmtheeeelldd3isiMsslttaoancnaccteeed Ntiiomemimtmtheheededisraioatcuteeotlhlmyyepaeeosaautss,nttaodocffrwottahhssese dtssheiiettteeeMcwwteieesrrdseeiisaansnnitpaahplleyyizszReeaiddmvpeffloro.errdPPWFwFeaOOltleSSsr. and PFOA by samples from and PFOA by the MDH Ia (see Figure 11). four residential wells located the MDH lab (see Figure 11). Neither compound was detected in the sampled wells. OPPuunbblJliiuccneCCoo2m4m,mme2ne0nt0t4ss adraf version ofthis document was released or public comment. Comments cwwOeonermreeJmuerrneneectcees2ii4vav,eer2dd0aff0rtro4aomcmahdEEerPdPaAAfa,ts,vMAMepPrPspCiCeoAnAn,d,oiW Wxfatah2s.sihshiindngogictoounnmCeConoutunwntytay,s, he Ciy released the City of Cottage Grove, and 3M. The for public comment. Comments of Cottage Grove, and 3M. The comments are attached as Appendix 2. dEEePPsAcArippbrreoovvEiiPddAee'ddssseeovvneegrroaaillngggeenwneeorrraakll ccwooimtmhmmetnehtnestps,e, raafsslwwoerelolllchaassemssiuucggaggleessittniidoounnsssiraayss tttooo issnppveeeccsiitffiiicgcaaltaenngtghuuesagsgoeeurttocoes, tdffaoaettxseeic,,croaailbnnoeddgiEttcrrPaaalnAnssa'ppscoocrorutntrgooafocfyiPPn,bEgi'CCnwsspoiairnnkrtbtwhheeeicteehannutvvshiieerroopdnnermmrafeeflnunt.ot.rriosEEckhPPaeAAsmsddieiicsddaslnnmoieontntdtrrueefsvvotirrieyewPwtFotthOhieenAvddeioosscctniuugommaetedennutttehffeuoorrsiourlcaetes, ot22o0s0x00u4i4mc..oelnToTthgh.ieecassTlppheeacecciicfMfuiicPcraCcccooyAmm, mcimneoenmpntamtsrsetnaabinnesddcawssuueusgrgeeegeaesmsdtotiirsoaotnfnltssyrmmigsaekadndaeeesrsbbaeyysisEEnmPPneAaAntutwwrfeeeo;rrreeMPiiFDnnOccIooArrsppiioosarrfnaafttoaeetdddddinurneettsousnetthhdtieeltlhaeter by cdcilnloaavcrreuiisfmftyyiieignnnaggtt.ittohhTneeshtteaeetxxMttthPiiennCsssAieevtvecearoranamldlmpptllheaaencctseestssawtddueeesrsseccorfrmiitbbhoeeesddtlcyiionnngttsehheneenetccraooolmmrmidmneernnetnabsttesu,t,rweiien;necM cnlluuDdtdhHiinenggMstttPahhfeCf Adadedessdaccrnrrediispps3tteiiModo.nnthoofepfmapsabstyt investigations at the site and the status of the consent order between the MPCA and 3M. W fWuarastshhhieirnngigtntvooennstCCiogouautnnittoyyn''sorccdooimmsmcmeloensntutsrseoggeefnneiernraafllollryymwawteeirroeniinrehtlhaeetiffvoeortmmo rooefflrereaecsceoosmmommfeenPndFdaCatstiiooannnssd tVoO33CMMsffaootrrthe fsssuiitttrae.tt.heemAAressninttthsvheeemscactioodgueuantniitotyny'tsshoeccrtooedmmximstmcoelenfontsttsushreaeappdoppfeeoaainrrcefeoddurmftomarrtneieeooiifnnnnufforrotertrclchaee,etirMMvceDDhtHaoHnssgreeoolsewwawnnseerreseescooomfmmaPmdFmeeCnefdsnosdatatnihtdieooVndnsosOcaaCunnsmddeant tthe risitttessaceetleolffmmaamessennatdesrsaemutsliualold.tne. siTTnmhhateehdeCCeitiettiyxynottofofefCCtdohortetataatdggoeHeceuGGamrlrtooehvvneetC,occnnoosomumlfmmutearetnthniteot rntl,ecthtieeanrnclgssuiiemdmsippwnllgyyerheeeexxmppnrraeeedessessdeetfddoocstsohuunepptppdoioornrcttuuffemordretnhhtee monitoring. recommendations monitoring. made in the draft Health Consultation, including the need for continued It 17 2200009..00001188 333MMM ossuunbbtmmhieittttceeoddnceelxxuttseeinnossniisvveeanccdoommrmemecenontmtmsseoonnndaeetaaiccohhnssseeccdtitiidoonnnoootffrttehhseeulddtooiccnuumsmiegnentni.tf.icGGaenetnnecerhraaallngcceoosmmmbmeyenMnttDssHff.rroomm 3SSpMpeeccioifnfiiccthcceoocmmommnecenlnuttsssiorrneesggaaarrndddiinnrggectthoheme ttmexxettnoodfafttthihoeensddoodcciduummneoentnttrewwseuerrlteeihhneelslppigffunulilfiiicnnattnhhtaatct htthaheneyygeccsllaabrryiiffiMieeddDccHeer.rttaaiinn thhhiissettsooerriicccoaamllmffeaancctttsss.rreegg3aarrMddiipnnrggovPPiFFdCCepdprmoriodsdusucictntiigooninnaafnnorddmddaitissippooonssraaelllaaattttitvhheeestisoticteee;r;tccahhiaannnmggoeenssitwwoeerrrieenmgmaaaddneed ttpoororreedffullceetccitton `twwhaeveelalslilesslacaabtotletmthhaemetsiesttnihetete.s.t. i33m3MeMMtaahpllerssooodvoppicdrruooemvvdieidmdneetiddswsssiaeensvvgeerfirianarlflstouurwssmreeiffatuuttlileonttn,ooxxraeiinccldaootllitoovhggeeiisccteoaallrcerreefereffteraereirennencnmeccseeosshnattihtvhoaeartibnwwegeeerraneenidnnnoocptltruoddedu.ction `aSScpvpeoaecmicilmiaffebiinccletccsaootommntmhmteehentenitmtspseootonnhettootdxxoiiccfecoooulrlmoodnggeeivincctetaallwloiiiapsssmssaueufeinersstslatwwlweerrreieeftftaaeeddcntdd,srraeefnssrdssoeetmddheewwsxieipttohhrsetutfhhereereemmntaocajejPoosFrrhOeeaSxxvcce(eespbpcteteiieoon3nnoMifonftccltohuhmedemeedn.ts, cpp2oa0agmgoeefm11he22instiisnndoAAonpcpputphemeenendnpditoixxtteh22na))t.t.iTaMTlhDhfioisHsrccdomoeammvyemmleocenponnmttsewiwndeaetssarlaadpepepfpvfaaeerrcleetonsnpttmfllryeyonmiitnnaelrrexesesppfpofoosennucsstreese twttooohM eMPnFDDOHrHe'Sv'ssi(sessewtteaiatnt3egeMmmteehncnetotcmoounrnmrppeeanangtgtese:, 2HnHo0BBtoVVafddtffhrooeirrssPPsdeRFodOO.cSuS.m. eBBneetcctaahuuassteeMMMDDDHIHmiiassynnooctot nccuusrirdrreeennrttdllyeyvrreeelvvoiipeemwwiiennnggtattlhheeeffPPeFFcOOtsSSwHHhBeBVnV,r,tethvhiiiesswccioonmmgmmtehenentctuwwrarases.nt not addressed. ITIIIL. DDiissccuussssiioonn : PsPaeelrrsff,lluuaoomrromoccohhneeimmiuiccmaalplsser((fPPlFFuCCosrs)o),,ccpptrraiimnmoaaarrtiiellyy(ppAeePrrFffOlluu;oarrCoooocFccytt:aann0oo:iiNecH)aacc,iiddas((PPwFFeOOlAlA;u;sCCliseFFsIs1e~5r00a2;mHHo))uaannntdds ooonnfeeotoohffeiirttss PsPuasFEleCCtdsss,aatssmuutcchmhheoaasnisstiueppmeesrriffnpllcueueorofrr1loou9oo4o7ccr.ttoaaonnOceetnssauuenloloftbfaotnnteyyh!le(AffbllPuyuFopoOrrriiod;ddeeCuc((stPFPsOlOosSOSfFF2t;N;hCCeHys4pFF)r:I,o77adSSsuO0cw:2tFiFe)ol)lhnohaaasfvvleePesbbOseeeeeSrnnamimmsaoapnuneurnufftfaslacucototufurroroeeotddchteooarrnre cussnuuslzelffdyoomnnaaaatttttieehce((PhPsyFiFtdOOerSoSs;l;iynCCsciyessFFo11if797S4P0O7O5.3S)"O)F,,.nwwehhTioihccfehhtshcceeaancnbahylaeplsmsriooocbdbaeulecsptapsrrroooeddufuutshcceeeedddpbbbroyyydt3tuhhcMeetissoauunnbbdssoeeofqqtPuuhOeeenrnSttcFocchhmisepempmaienicricfaeallusl oooarrrroooucntadne ettphehneseztywiwmcooiradrlletddisc,iiahnnnyttddhhareeospplyrrioosnidddsuuucoscttftriiPiooannOlosSoufFfrf.ssatacaTitinnhanertrseeseppeecallhlnleeednmnttesismc,,uallllussuibbafrrriiiececaraunsnsttes,,dffbiiryre 3rrMeettaaarrdndaadnntotssthaaennrddcssouumppppprareenssisesaasnntatsrs,o, uaannnddd pesticides, and as industrial surfactants and emulsifiers. "TrTehhseueltcc,hhetemhmeiiyccaaalrlessttprreuurccsttiuusrrteeessnotofofnPPcFFeOOrAAeleaaannsddedPPFtFoOOtSShemmeaankkveeirttohhneemmmeneetxx.ttrreOemnmeetllhyyerrbeeasssiisiststaaonnftt (tiotsbbprrheeyaaskkiddcoaolwwnn.. AAssa.a rpp(errOsooupEpeleCtr,rtDtitihee2ses0,y,02PPa)FFr.eOOpSSIedriiissssieescstshesseanenrtntgtoiieanaldlclleyytornneaoolinenr-a-v(svoseoludalcatthitoillaeets,h, edaaunnerddnivnwwigorooupunlrlmodddeunnncootttt.biboeOenoneefxxtphpPeeeOccbStteaeFdsd)isttooiot eefwvviialtaslppoporrhraaaypttsieeilcfyfarroldomempowwsaaittteerrto S(OoiEl CanDd 2d0u0e2t)o. iItsf dlioswchsaorrgpetdiotnotaeinrd(esnuccyh, aosncdeuriinngsopilroitdutecntidosn0ofrePmOaSinF)thiterweilwlirtahptidhelymdaejpoorslitostso dsouiel 1a0ndrudnu-eoftfotiotssulorfwacseowrpattieorn (teDnMdeEnRcy1,9o99n)c.e iInnsfolialtiit otennodfswatotreermcaoiunltdhealresowciatrhrtyheit mntaojotrhleoss dsrsuueubbmesastuuiorrnffraaiucncnee-wooaorftrfeiitrnonttdoosuuggerrrftooaouucnneitddswwwsaaotatleteuerrbr,i,(lDhhitooMywweE(evtRveyepri1r,.c9a9lII9nln)y.ss8ooIii0nll-%f-wiwlatiartntaeewtrriaommtnieixrxottfuaurnwredesas,t2,e0PPr %FFcoOOiuSnSldshhoiaalls)s.aoaa scPtarrFsroorOnnySggitdtteoeinncntdsdoeennnthoccteyy ttoo. reeamsialyinaidnsowrabtetor sdeudeimtoenittss,soalnudbiilsiteyx(pteycptiecdaltlyo b8e0%mobinilweaitnerwaantde2a0t%eqiunilsiobilr)i.umPF(O3MS 2d0o0e3s5)n.ot easily adsorb to sediments, and is expected to be mobile in water at equilibrium (3M 2003b). pPPrFFeOsOsAAuriiess (lsEliigPghhAttll2yy00mm2oo)r.ree PvvooFllOaatiAilleeistthvhaeanrnyPPsFFoOOlSuSb,,l eaallatthnhodouucggohhmpitlsestttiilellllyhhaadsiassaasvvseeorrcyyiallotoewws volatility vion lwaattileirty, and vapor ainndaqvuaepoours SpsIoornleluusltstiiiumoorinneteii(dttEmmsPtaaAuyydi2ello0so,0oos2sPee)l.FlyyOPccAFoolOlhlleeaAccsttissaahttvottehwhreeyn aasaiiorhrl/uiwwgbaahtlteeemrraobniinidnltteicertrofyfmaaccipeenleaastnnoeddlmyeppdaasrirotstiiialttsiiostooynnpcebbiaseettte(wwsEeePieenAnnwtt2ha0hte0ee2mrm);.((i3n3MIManqa22un00e00o33u4)as,). aItntelimmptitetod esstutidmieast,e PthFeOpAotehnatsiaslhofwornlaonhgi-grhanmgeobtirlaitnyspionrtsoomf ePFsoOilAtyrpeleesa(sEedPAto2t0he02a)i., IFnraannklin a((t2ot2t00eu00mn22d;p;uetnurtpgnouopbeudslbrtiliyimssohhareetdewdetrrhteeeppdooeprprottotseooinnnttiiEEaoPlPnAfAwo''irsstlPPohnFFigOaOn-AArfaenwwwgeeedbbatryssasiint,tes))bpussotttraatctteooedudflPttdhhFaauOttnPAPdeFFrrOOeclAAeeraeetsammeiidnittittcoeeoddntthdtoeoittatihhioren, saaFitirrraainisvskelllliiiknkaeellyy tdoisutnadnceergoofudprytoor8w00eKtidleopmoestietirosn fwriotmhitnhea sfeouwrcdea.ys, but could under certain conditions travel a distance of up to 800 kilometers from the 1s source. 18 22000099..00001199 IIalnn a(as2ts0tu0u3dd)yyfoooffunPPdFFCCPssFOiinnSggcrrooonuucnneddnwwtaratateteirroaantstaaufpfootrromme1er2r 0mmigill/iitaLarryyanffdirreeP--tFtrrOaaiiAnniiannsgg hsiiittgeeh iiannsMMi1c0ich5hiuigggaa/nnL,,nMMeoaorootddhyye eett aooMrlriDi(gg2iHi0nna0aHl3l )ccBoofnVoncucrnrweedetteerPepFpaafOddoSuuunscsdeeoddnincffeogonrrrtotrthuahenteidottwrrnaaasiitnnueiiprnngg.at.o CCf1ao2orn0ncacetwiengant/yLrtraaaattsniiood5nn0Pss0oFomfOfeAPPteFFraOOssShfiraagonnhmddatPPshFFe1OO0p5aAAd.~iintngT/eeLhxxecnceeefssaassrcoiftolhitfetthyhee wM wPaEaDsCs sHuusswHeeeddBrefVfoorsrrowffuiitrerieern-e-ettrlfrayoaiiununnisindneggdinffirrnogomtrmorau11inn99di55nw22gauuetnnxetetririllcaitsthshfeeas.reeaaarrwTllyhyaey1199ra9es90s05sus0,l, 0taannomddfetfftiehirrereessffftiriugogdhhmyttiinitnnhggdeiffcopoaaaatmdme.ssthTccaoohtnnetPtafaFaiiCncnsiiilnniigtgyn PaadiqqFsuuCteeasoonuucwsesessrseowolilruutothtuiilootiinntnteaaerlroyeerauesasnsieoidllyyriencctaaatrprpadaaiabbntlliieenognoooffemfxmietgirhrgceariastcetioisnnn.ggtaTiimnhnittenooarggnerrtsoousuultntnsdhdwrowaoftuategthrehe.r.asdtTTushodhreyepyytiniccodaaninnctattortreaatvvhteehellaateeqxxPuttiFeefCnnedrdseeiddn `dsscuuiobsbnststattanrriaacnttesees,,awaasnriitddmhiccllaaaitnrntlepfpereorerrss-iirnssaotiffrnooeirrtnayygreedaaaarrrtessiaoaanwffhteoeerfrrtttehhheeefyyicrowwnefetriargeemhtuuiinssneeagddntfasaottattthmhhrseeoucggogrrnohotuuaannidddnsiossnurugrprftfPaiaocFceneC..stoTTwthehhereee33aMqrMeupissofiierttetreed fo chh3oaaMvnveetfaibbinreecsee-nnatauusiissnmeeiddnilga((ErsEiRftRierG,Gea-22ctr0t0a0u0ia4n4l)i).n.igtW WeahrchiehilalaeewrttahhhceeetrsseeittrfeetirsssetttuwufididigciileheslddtidnbbegyytefM Moroamomioondsdeyyctohcetnet..tpaaaloil.nt.eihhnnaatgssiaPsslFoomfmCeorsesPwismFiemiCrlesialrarioretipiteioeensrstteettdroo ttttohhheee g3rgarrMoionuufinninrddegww-atsarittateeei.rnr iaannngdd migrate away site, actual site migrate away from the site. This characteristics will from the site. This hhdaaesstennroomtt iyyneeett been evaluated at the the potential for PFCs been evaluated at the 33toMMeffniirtreeer-- the training site. dBBeeeacclaaouufssteeooxofifcttohhleeogrrieecccaeelnn,ttewwpiiidddeeessmppiroreelaaogddiiicnnattlee,rreeassnttdiinnenPPvFFiCCroccnoommemnpptooauulnnmddossnissutuoccrhhisanssgPPiFFnfOOoSSrmaaanntddioPnPFFhOOaAsA,b, eaagcgrreeaatt dpueballiosfhteodxiincogloovgeicranlm,eenptidaenmdioinlodugsitcrayl,raenpodrtesnvainrdonimn epneetarl-mreovnieitwoerdinlgitienraftourrme.atiMounchhaosfbteheins prrteheusesbeeglaaiersrnchcehherdahhlaainsspobgbpeeoueevlnneartffniuumonnndedenefddtroaoomnrrdcecxooinpnndoddsuuuusccrtttreeeyddPrebbFpyyOo33ArtM Msw..aansM Mdoposiunstbtlprrieeesecchreee-nnrdtetllvbyyyi,,eawaBnnuedatannealainltlyehysrsoaiifstseouftorfefat.lthh(Mee20upp0oco4th)tee,nonttfaiianathldlisrr3iissMkk ttoo thafhoaselslgppoerrwonoieddnruguacclreeepddporaapennsueluuanppttidsdoaanatteebfddrrioeeemfnnsvveiuixrrmopomnnoammseruenrynetotaaPfllFaaaOvnnaAddilhhwaeebaaallsltethhpiuaanbfsslossireesmshsassetmmdieoebnnny.tt of PFOS (3M 2003b). Butenhoff et al (2004), ofPFOS (3M 2003b). Theand The 3M following represents a brief summary of available information. `SASnuuimmmmmaalarrysytouofdfTieTosxoihxcaiocvoleologsgihicocawallnIIntnhffaootrrmmPaFattOiiooAnnand APFO (its ammonium salt) are easily absorbed ttA1hh9nrr8oio6muu;ggaKhhl usiidtnnuggodeeisasetntsiidoohnnKa,,vaiiewnnahhsasahllohaawtitiimnooannt,,h2a0aa0tnn3ddP).FddOeerPrAmFmaaOalnSdccooiAnnsttPaaalFccstOto((wE(EeiPtPlsAlAaam22b00sm00o22or:;nbieKKudemenonrnnsaeealllddtyyy), ab11ru99et88e55sa;;sKKniloeyetnnananbbeessddooyyrrbbeeeettddaallwell Gtt1hrh9rro8oov6uu;eggKhhfauiicndnihhloiaatlalyaanttwdiieooKrnneaooworrcaddcseeuhrrpimmamataaillo2ccn0ooanl0ntl3taya)cc.ettxP((pOFOoOEsESeCCdDDisto22a00lP0s02Fo2)O).w.Ae,IlIlnnaantthbdheseoippraabisssettbd,,ewwoloiroarerlvkkleeyedr,rsstbhuaaattttttidhsheeenro33mtMaMalb--asCbCosorootbtrtetpaadtggiweeoenllof GPPBoFFrtoOOhvAAePfwwFaaOacssiAsliistgaiygnnniwdfiefiPirccReaanOnotStcc((auEErpPPeaAAdtiio22snt00ra00il22lb)yu)..teeOxOdpnnaocncsedeeadafbbostsuooonrPrdbbIe~emdOda,,iAnAA,lPPaynFFidOOn ittddhiiiessssabbsslessoloooicecdiviaaesttdeeersstuhotmoa,ttthdiheveerePmPrFFaaOlnOdAaAbksaaionndriinpoeotnyni..on of (aB(EnEodPPthAAarP22eF00eO00x22cA;r; eKaKtnuueddddooPinFaaOtnnhddSe KKuararaeiwwnadeasissahhtnriidimmbafuaete2c2ed00s00a33an;t;ddOOifEofEfuCCenrDDdentm2200ra00a2i2n)t.)lsy. iiPPnnFFvtOahOreAAiobaualonsnoddtdePPsstFFeOaOrunSSmiaam,rraeelivsnnepoorettcammineedetstaakabbinododlnliiezzyeedd,, ahhantuusmdm,aaanbrnsue.st.etxhTTechhsreeeerdtreeiedfaafillenssrooethnaaceppeppuseeraianhrreatovoaebnbedneoftsseiicgggeennsniifefaiirctcaaaldnnlittfyfggebeereennenddnteerorrabddtsieieffsfrfeivenrreeedvnnaccireenissohuiiinsngheeteexxrscctrareaentntiiiimomoannlarrslaasattepenssdecffhiooeurrsmPPaaFnFnsOdO.AA Tiinnhe remeassatttlsiim,embraaautttetesddththheoaaslhleffu--dnlliiidfffrefeeeoodrefsfnPPocFfFeOsOhoAhAuarviisnneiaannnnoiidtmmogagaleslsnse(rrrKaaanunllgdgyeeossbaeffnrerdonomKmoabffwosoeauurrhrhvihoemoduuarirnss20hii0nni3g)ffh.eeemHrmaaaallnleimrralaattisslvseaasannonddfdnnhiPinnuFeemOddaSaanyyshss.aviiTnnehe mbdboeeaseelinneneegrassstttsitimumtodaayttheeudidnnaacdttyroeonvdvoesemrrool1f1g00h00uodsudaryamsysosinnkiindneoyrrgasatsts((iiKOnnEuaadCssoDiinnag2gn0llde0e2--Kd)d.oaossweeIansshattiuumddlyayi,m,2iaa0tnne0ddd3)s22.t00u00Hdyaddolaaffyy-slrsieviitnenisraaeodssfuu3Pbb-FM-ccOhhwrSrooornhnkiaieccvres, tdPthhoFeesOimmnSegeawasnnatusssdeeeyrsrutuimnimmcahhytaanelldfof-lmlaiitffoee8lg.oou6ff7sPPymFFeOoaOrnAAske(wwyEaasPss(AOeess2Ett0iiCm0m2Daa;ttee2Odd0E0tto2oCb)bD.ee I44n..3a377liyymeeaiatrressd,, 2002). and the mean halE-Iife of study of retired 3M workers, and the mean half-lifE of PFOS was estimated at 8.67 years (EPA 2002; OECD 2002). EExxppoossuurree ttoo hhiigghh lleevveellss ooff PPFFOOAA aanndd PPFFOOSS iiss aaccuutteellyy, ttooxxiicc iinn tteesstt aanniimmaallss ((KKuuddoo aanndd 1199 22000099..00002200 KvKaataswwatayssphhiiicmamlaaly2200re00s33u;;ltOOsEEinCCeDDdu220c000i22o))n..sCCihnhrrbooonndiiycc oowrerissguuhbbt--ccahhnrrdoonnwiieccieegxhxtppogosasuinrue,trtaoeondllooiwwneelrrveddeoofssfeesseocoftfsPPFsFuOOcAAhaiisnn an rilinainvtccserrreetyaaassppeepiceiiaannlrlliysivvoreeerrsbuwweelteistighgihehnttprraaeinndmdduacraatyllitotetenrarasratgitienoitnobonsordiignyanIlwoippifeiddigPmmhFetetOataanAbbdootlwloiixsesimicmgiht((KytKguuinaddioorna,taasann,nddadlKKtianahwwolauiavgssehhhrieimefmffafacec22ct0t0ss00o3s3)nu.).cthhTTeahhseean klKliiiivvddeennrreemyayspas,p,yeppaabarnensccrmtroeoeaarbsse,e, stteheessevtteesprs,re,imnainnaddarygooevtvdaararrargiiteeessts oh(arBavgvaaedenraaolalssfnoodPFbbBeeOieerAnnnobotobabsxuseemicrr,ivvt2eye0dd0in4(()EEr.aPPtAAsE, 22xa00lp0t0h2o2)os.)u.ugrThTtehoheeefPfeeeFffcffOteesAccottssninootrnhnaettshhee rllrieeivssmeuuirltlttemssdaiitnynoaabraeppthshmeeaonnnroodemmsseieenmnviooelnnraeiinienntsthhateegaellndiiivvmreeaarrltskks,nn(oBoawwnaddnniraaassnnppdoeetBrroooirbxxnsiisbesoaromuvmemeed,ppir2rnoo0lpl0iir4ffiee)mr.raaatttEiieoxosnnp..oosrTTuhhhrieiussmtoappnhhPseeF)nn.OoomAmSeeoinnnmooernnaotiifsss the aaalidtdmvrveibetrruessdteeetdolliivtvreaoerrtspeeeaffrfnfeoedcxttissssimooobbmislesaeerrprvrtveoeelsddit faiiennnrairamtatitasoslns((,ssmuuaaccnyhhd naaiossstnaabnnoetiisnonecbcerrsneeeaarssivneeedhiininignllhiievpvreerirramnwwiaeemtieaigglshsht(.t)o) rttAhhhdaauvttmeaararesenesii)nn.lippvSaaerorrttmefefeocftsthe ainttrhiibguhteerdatnoipmaelrosxairseomliekeplryotlhifeerraestiuolnt omfaaydniofftebrentsemeondienohfiagchteirona.nimals. Adverse liver effects in higher animals are likely the result of a different mode of action. aAAdv99e00r--sddeaayyefssftteucudtdsyyooonffrrteehlleaatatiidvvreeellnyyalhhiilggahhn--dddsoo,sseebooorrnaaell mPPaFFrOOrAoAwe.exxspppoolsseuuernr,ee liinnymrtphhheeasstuuisscmmsoyonsntkkeeemyy,ssanrreedssuudlletteaeddthiinnin some eaaandnxipvimmoearsaslelessde((0EfEfPePdAciAtfsf22e0o0r0n0e2n2)tth)..edoAAassdeirsseixoxn-f-ammlAoogPnlntFatnhhOdssstst,uuhbddooyywoneoefdfomortraaoarxllriocPPwiFFt,OyOs(AApplereeeixxnppm,ooaslsryuuimrrlteepoyihitnnahtmmicaalllsieeyvesccrtyy)ennmatoo,mmvaoeonldlngguudtssehaemmtholononiwknkeeessyyotsms e mdedooxodspsieeofsssiesscdttauuttddoiiioeednddi..offfeEEtrxxhetetnrrtedemdomoseesaetgtosoexxoi1iccf0iiAtptyyrPewFwvaOeasnstsoohtbbhossweedrrevevdeaettddohxaaottifctttihhtheyeehh(piitggersihhmteesasatntriieelmyxxappltooossstuu(hrrBeeeullltieevevveenerll)h,,oappctfrrtTeoovmmaelppn2ttit0nhi0ge2n)gal.owEevset n bwmweiiosttahdhcirttfhiihcfeeaicddtieooodssn.aaggoeeAf taahsddeijjmuudisslottamsmraeegcnneottn,,tdoooitnnpieeroettnveeessdtntetaavnntehilimemoapdaleledaaatttihntthhooeefnethhhoiieggfhhtteeehssstett addlnooosiswmeeesabbtleescdc(aoaBmsmeueetgeeernxxohtturorepefmfmaeenetlilymyaalliil2sll.0aa0nn2Tdd)h.hheaaEddvtteoon tutboonexxkisinccaoooclwrlooinfggi.icicceaaAdll. smmtAeeecacsdhhiyama-nnsiiltiasasmrtmecoffcoonorrndtctihhteieenotnaarppadppteaiavroreeennlonottfpeeePxxdttFrrieOnemAmoeenieaantddovhvfeeetrrhssseeeerlrruoeemwaaccewttsiiatoosndnorinsneeattchghheereossdeeupwttwiwatoonhiiaamnnnaiifmlmsoa.aullssTtohiissesix w(uwpenepkcemnkk)osswaiannfft.eterhrAeddloossosteiwinandgdgoybbs-eeesggtagaatrnneo;;ucmmpoeneoaacnnen1ss5tere8arrutpuimopmnmPPoFFifnOOPtAAFheOcchAooinngccihenenndtthtoeresaaettsiieogornrnuossmurrpaawnn(aggBseeuddrteffearrcnoohmhmeodf7c777fwt ippatalahrri2ttns0s0fpp2oe)eur.rrmmtioTillhllsiiiioxsonn sa(sprttueupddmvyye)rddiyiinddsttdhdeeeeemmplooon--wisnnisddrtrioaactsteaeetgttihrhnoaagtuttptdhhoetohsdae1os-a5smr8ee-atprsleppsmpioonnicnnsrseetehascecehhhaairinrgaachdctotedesroreiisssecttaiigccnssrooboufefpaAAs(PPsBoFFucOOiteantiinehndotthhfwifiissetthssappaleecc2sii0ieeg0ssno2io)ff.ficmmaTonotnhnikkseeyy increase are very increase in the number or severityofadverse effects. steep - indicating that a small increase in dose in the number or severity of adverse effects. can be associated with a significant EdEexxapptohos,suuwrrieethssttauuddsiiteeessepooffdoPPsFFeOO-SrSesiinpnorrnaasttsse hhcaauvvreeveaallfssooor ddmoeermmtoaonlnsitsttryraaottbeesddeeerffvffeeedcctt(ssOooEnntCthhDeel2li0ivv0ee2rr),,.wweIeiniggshhtttudlliooesssss,,oaafnndd dPdPeeFFcaOOrtheSS,asweeexxipptihoonssasuuersrreeteiueimnnpchrrdohhloeeesssseuut-ssreemrmsoopolnon,knkeaseyneysdsc,,audaarrvddevevneeafrrolssreeemfeeffefoffcretetscca.ttlssitSyiirir~omccibllluusaddereervddeefaadfnneo(ocrOtreseExxwiCieaaD,r, ecc2ooo0nnb0vvs2ueu)lrl.svsieioIndonnssi,sntua,asdtmmiueadasrirkeokseefddof pcdceyyercnniroooemmda,osolealggniudnusssimenmrofounamnkckteeycsysho.som.leeTTsrthheeeercooaalvdd,evvareenyrrdssweeaadeesrffeffneneoccatttlessdewwfemfeerurceectshnn. oocSallrioomlnniiggrlee.arrr observed aftear 52-weck recovery effects were observed in studies of observed after a 52-week recovery period, and in fact some recovery was noted much earlier. `SiSnocomrmeeeaslloeonntggh--ettererirmsmkoaafnnciimmaanalclessrttuuoddiietefhss ssuulggivggeeers,sttptathhnaacttreeeaxxspp,oosasuunrdreettteoostPPesFFO(OKAAud((oaannaddnppdoosKssasiiwbballyyshPPiFFmOOaSS)2)0cc0oo3uu,llddEPA 2s2inu00cg00rg22ee,,assOOtesEEtthCCheDDarit22sh00ke002oc2)af).n.ccaeTTnrhhcseeearmmroeeefcctthhhheaaennrliieisvssmuemlrt,ooofpfpfaoptntoucetmrneeotnairtsiaa,lplarccnoaadmrracctetiinsintoooeggnsee(n(nKveeisusaiidssooxiiissadnuuandtncicKlvleeeaaawrsrt,,arbebssuhustit,meecvvaeiil2dd0eedn0neac3ctee,hE, oPrA hso(ugoregrmnmgooetnoosenxts-iecm-timhetadyet)id.taihatetTeechddaenmmcteeeuccrmhshoaarannsriiessomtmbhssse)e)rraaevnnseudddltnnionoottfraffttrurosmommmoarddyipirrerboectmtaddoraateimmosaunalggt(eevoifttaoopottehxhreeiodgxgaeietnisnveoetemtiiesccptrrmmeaosatlste,efrrceiieraaa)llltwwidoieintta,hhtiihann,nodcceerllllss may not be seen inhigheranimals or (genotoxicity). The tumors observed may not be seen in higher animals or bein be of relevance in humans (Kennedy ct al 2004). rats may be a result ofperoxisome proliferation, of relevance in humans (Kennedy et al 2004). and VVaarriioouuss rreepprroodduuccttiivvee ssttuuddiieess ooffrarattss ffoolllloowweedd ffoorr ttwwoo ggeenneerraattiioonnss sshhoowweedd ppoossttnnaataall ddeeaatthhss aanndd 20 20 22000099..000022~1 oaotnthhdeerAr PddeeFvvOeello(oppEmmPeAennt2taa0l0l 2ee,ffffOeeccEttssCiiDnn oo2f0ff0fs2sp)p.rriinnTggohoeffsfefeemmsatauldleeicrrsaatdssemeeoxxnppsootssreeaddtettootrrheealltaaettiixvvpeeollsyyullrooewwtoddooAssPeessFoOof/f PPPFFFOOOSAS `aaannnddd APPFFPOOFSOS cc(aaEnnPArreess2uul0ltt02iinn, OaaddEvvCeerrDssee2ee0ff0ffe2ecc)t.tss on the offspringofrats exposed while pregnan, These studies demonstrate that exposure to AI?FO/PFOA on the offspring of rats exposed while pregnant. AAfottrttdhhreeinrrekeqiqnuugeesswttoaotfefrtthhfeeorMMPPPFCCOAAS,,aiinnndNNPoovFveeOmmAbbeoerfr 22| 00p00p22bMManDDdHH7 ddpepebvv,eellrooeppseepeddcHtHieevaaelllttyhh,--BbBaaassseeeddd oVVnaaleluuxeiessst(i(HnHgBBVVSs)) ttcfooooxxrniitdccaroomillniooknggiaiinccngaatllwiiinanndtffeororirrmnfmokaairttniiPogoFnnwOa((StllieivvareenrrtdhttaooPtxxFiiMcOciiDtAtyyH;;ossfceeoe1enspAAipppdbpepereansnndddtioi7xbxep11)p)s..ba,fTTerhheeefsoprHHechBBtuiVvVmsealrrnyee,pcpbroreanesssseeundemtnpoatatnilleeoevxvnoeeisllvtoioenffrgaaa cleliifofffeneetttciiamtmmsee.oi.ncacTTnuhhtreeianHHt dBBlreVVivneklddsioonchcgiuugmwmheeaenrtntetatrhatttaihinooanntdMoiinnsDeAAsHppappsceesonnondcdsiiiixaxdtee11rdssswtttaaoittteebhssettlhsihaavafteerrtefeooppxrrriocohiddutuuymc.cttaiinvHveeocwoaaennnvsddeuddrmee,pvvrteeielolcooneppnmmotevesnetntrutaadaliles eoooffnnfcePPocFnFtscOOeoSSnc.c((TuThrhTiiahbbteoolsddeeveeaaeruluesxcxeheenitttgahaslletur22d00tih00ea33sn;;mLLdaoaaysuueleesettaaaadsllsMo220c0Di00aH33t)e)dtssouuweggixggteahesmstlitivntthheeaarttdtoeddvxeeeivvcleeiolltoypomp.pemmHneetnonatwtlaaleltvoeeesffirff,ceeircctettyscseammnasta3yystuaalldssiooesbbee. oppaowofsascsisoitinbbilclneeegrbbnfaau.ssriitTsshehffreoosrrientthfhreoeercPPmeFaFntOtOisSoStnuHHdoBiBreVVsg,u,miwwdahayhinicclcehehadcfcoorMuuolmlDddEHrrPeetssAouulletbtxeiifannomaariedndiieiffnffideeteirrveaetnneitltnoHgHpaBmBVVreenvfftaiooelrrwtPPooFFxfOOicStSih.t.ey MMasDDaIH HBVS iiss for `aPPawFFcOcaOoiSStuinnaatgnnoddfruPPrctFFhhOOeiArlA.di.nhofNNooordotmteeeaxtttpihhooaasntturMoMerDsDg,HHuaidniidsasnaatcllhsesiosofcriinonhmatthnheeEgePppArrcoooccubeelessdfssoorrofeesfruirelnevtivitiiisnsaiittninnhggegaallallolrwHHeevRRriiLeLnwSsg ttooooffammtlholoerrHeeHddVBiiVrrSeesccbttfllyoyyar factorofthee or four account for childhood factor of three or four (see Appendix exposures, and (see Appendix 1).this 1). change could result in the lowering of all HBVs by a AAfollrssooboaattthtthPheeFrrOeeSqquuaeensstdtooPffFttOhheeAoMMfPPC4C0AA,p, pMMmDDaHHnsdtsat2af0ff0f ddpeepvvmee,lloorppeeespddeciitnnittveeerrliimym. SSoToiihlleRReSefRfeeVrresennaccreeeVVsaoaliluueeesvsa((lSuSRaRtViVos)n) cfcsorrkiirittneebrrcoiioatanhtffoaPocrrFtpOp,rrSaootnteaedcncttdiiinooPhnnaFoloOfaftAippoeeonooofppfl4lee0vaffprprpooommrmsdadianrinrdeedc/c2tot0rcc0oocpnnotpntaamtccat,tmwrwiientisatphhteecccdootinnvstoteiaallmymip.iannraTatthtieeceddlseSsosR.oiiVlltSsthohiarrlrooeuucgogsohnhicleiinnengtgvereasasltuttiiiaoootnnin,o,snat or below the skin contact, or below the SRY are considered to be safe. and inhalation of vapors and/or SRV are considered to be safe. contaminated soil particles. Soil concentrations at bIInondssyuu.mmmmSatarurydyi,,eshhuuimnmataennsteeaxxnppioomssauulrrsee sttoohoPPwFFOtOhSSataaennxddpoPPsFFuOOreAAtolleeahadidgtthooctthoheencbbeuuinilltddruuappotofiffottonhhrseessseeufccfhhieecmmiieincctaaltlissmeiin.n tthhee abpploeesrrdoiiyoob.ddessSemmntuaaodyybiesccseaariuuvnsseeetdeaasitddnvvateenhrriessmeeoafeelfsffsffpseehrccitotsnswgoootnnfhtathrhtaeetesxllieipvvxoeepsrruoaasrnneedddtoootttohhhiePegrrFhooOrcrSgogananancsnse.d.ntADrDPaeetFvivoOeen.llsooppfEmomxerpensnotustaafulflriceeeiffefftneeocctPtttssiFmhhOeaaAvveemay b`baeleSsuoaamssbmsseoaocerciniyaaoottfeebddsEewwpriivittdehhedmaaiinnnoliitnhoncgecrireoceafaafsslseepdDdrairrtniisagskkooofffrccaetsreteaxinprtotyyspeptedessotaooffPcicFaanOncnSceerarniidnn AssooPmmFeeOtt.eessEtt xaapnnioimmsaularsles..to PFOA may "`TSTmuhhameenu33mfMMaacrtyCCuooormemfopEpfapapnniedyyrefmhhlaauissoolrccoooogcnnihddceuaumclcittDceeaddaltaaas mmseiedndciieccaaaltllmmeoaonsntiitttoohrreiinn1gg97pp0rrsoo.ggrraTamhmeoofcfeoemmmpplaponloyyyeeieneisstieeannllggyaamggeeeaddsiiunnrtethhdee ttPmooFttaaaOnlluSssfeeawrrcuhtumuemrneoosrrouggfcaaphnneiaiccrnfalfflulluyouosorroeriiscnnbheeee.. mcIIainncmattehlhseeasvmmiainiidcdl-e-a11ba99lt9e90l0e(ssaO,,slttsthhteheenecceoo1mta9ml7pp0aa1snn9. 9yy8T;bbheeeOgglaacsnnoemnmmepceaatasnasuylurr2iiin0nn0iggt3ias3sle;elryruOulmmmseePPanFFscuOOtrAAeadl aanndd 2`P2a00Fm00O3e36aSb)n).w.sheAAernussttmsuuuddPcyyhFooOaffSn3a3clMMyonsceeeesmmnpbptlerloocayatyeimeoeeenss aoaavtftait1itsls.a3DDb2eleecpcaa(attOtusurlrs,p,eeAnArllemaatibbalaallmmo1aan99PP(8FrF;aCCnOgmmlesaean0nnu.uf0efa6tactactoltuu2r1r0ii0nn0.gg036aff;aapccOpiimlllisi)tetieneassncdssthhaaoo!wweedd `ammmemeeaaaennnanscseoesnrreucurmeumnmtPPrFaFPtOFOiOAAonSsccoocinnonccneeecnmnetptnrlrataorttayiitoeoinoenosnofaoftf13.171M..873'82spppppAmamnnt(s(wrreaparnenpgrg,eemB00iel..l0l0i4o4gnit0ou(mr11a22fna..g7c7ei00li0ppt.pyp0m6mw)e)toriienn1a220p66.0p336roeepxmmpippmmllaoo)tyyeaeelneeydss..0a TT%hhee mleessan(Oclosnecnecnttraalti2o0n0s3bin).emThpeloryeeweassatn3oMas'ssoAcinattwioenrpb,eBtweelgeinumscfraucmiliPtyFOwSeraenadpPprFoOxAimately 50% `oclecbososnsnecc(reeOvnnetltsrrdaattniiinooetnnthssiaslaanng2ddr0o0ddu3eepbcco)rrf.eeeaaTssmehepddelrosseeyewrreuuaemsmsnccsohhuoocallhesesssatotseecrrihooaaltlsio((bonoerreboonettthhoweebrerseeccnroovmsmeemmdruooimnnnabPbniiFiooOmlloaoSlggiiasccntaauldldippPeaasFr.rOaammAEeextteperorsss))ure to coPPhbFFosOlOeeSSrsvteaaednnroddilnPPmtFFheOOitsaAAbgorhholaauissspbbmoeeaeefnnnedmssahhptooleowwrynne(euiinsnsuttseaeusslcttyhaalnnaosiimwmheaaarlls)ssbs((eieinenrnccullmuoudbdliisinnepgigrdvppearrdniimdmianactthaeeonssl)i)emsttotaoeliirnsnotttlueerdrcffioeeenrrscee.ewnwEtiirxtthahptoisounrse to cholesterol metabolism and alter (usually lower) serum lipid and cholesterol concentrations. 21 21 22000099..00002222 APAFssOeeppAaarraaatttetehssettuCudodtyytooafgferreeGpprrrooovddueucctftaiicvvieelihhtyoorrsmmhooonnweeessdiinnnommsaaillgeeni33fMiMcaeenmtmplplilonoeyyaeereeassssoooccccciuuapptaiatotiinoonbnaealtlllwyyeeeexxnppsooessreeuddmttoo PPPFFFOOOAAA cacotonnthcceeennCttrroaattttaiiogonne aaGnnrddovtthheeefmmaceeialasistuyurrseehddohhwooerrdmmonononeesssi,,ganallitfthihcooauunggthhlimmneeeaaarnnaccsoosnonccceienanttitroraanttiibooenntsswooeffenoonnseeerhhuoomrrmmoonne.e (`(eeasbsttorrvaaeddi3ioo0ll)p) pwwmeerree(O11l00s%%enhihcgtighahelerr19ii9nn8)tth.hooTssheeieesammsppsllooocyyieeaeetssio((ffniivvweea.isinn caaolllln))fwwoiuittnhhdeaasdseebrryuumam hPPiFgFhOOAbAodccoyonncmceaensntstrraaittniidooennx aiipnnbpottmhvheeefoff3riiv0vteehpeeepmmmCpoplt(lotOoyaylegseeeeesnsG,,rehhotoovawwleeev1wve9ore9r.r8k.e).rSSseeT.rrhTuuimhsmeaPPhsFsFioOgOchAAieatrcciooosnnneccrewenunatmstrraaPcttoFiinooOfnnoAssuicinnnodnttehchdiiessnbsstyttauuatddihyyoingrrashannobggboeesdddeyrffvrmroeomdamsis00n1itsn0oodme11ex11.55. wpWwopeorrmrkekeefhrorissrgthiihnneertthhCtiihssoatssnttatuaguddeyytGhsseruuoDggvggeeeesswttssocrtthkahaeaantrtdsoo.tAcccncTutuuhpwpeaaetrthriiioopgnnhafaeallcrieeslxixetprpiuoeomss,suruaPenrFsdeOt/tsoooArPPtcFFhoOOtnAcAtaehnatetttretahhxtepeiooCCnsousotrtotetabasggsweeereGGvrreerdooovvieenfaff.saaocimlilieittyy wllfoooernnrggweeeorrhrikddgueuhrrraesatrtiitoiohnnn.a3.nMNNastootDhaaeesscssaDootcceuiicraaattatiiuonorndnabAbneendtttwwAweeeneertnnwpssefeearcrpriulumfimaticeeeissls.itttrriaaeddsi,iooallnaadnn/ddorssteehrrauutmmthPPeFFeOOxpAAoslleuevvreeelslsswwweaarsse ooobbfssaeerrvveedd for workers in 3Ms Decatur and Antwerp facilities. eMMpoirodtreatalmliiittoyylooofgfiecemampllpsolotyuyedeieeesss aa(ttGtithlhleeilCCaoontdtttaaaggneed GGMraroonvvdeeelffaacc1ii9ll9iit3tyy; hhAaalssexaaalssnoodebbreeee2nn00tt1hh)ee. ssuuIbbnjjetechctetooefafrssleeivevererrsaatlludy, GeG2ip,il7illdl8iie8llamamnniaddollaaeonngdadincMMdaal7ansn4dtd9ueedlfliee((sm11a99(lG99e33i)le)lmirrlpeaeplpnooodryrttaeeenedddsttMhwhaahtatontthdhweeeoloor1vvk9eee9rrda3al;laltAsstttlhaeaenxnddfaaaancrrdiddleiiizrzteye2fdd0o0rmm1oaor)t.trtaaelIlnaiitsttyytherrsaaiettxiaiomorssloien((SrtSMhsMtsRuRdb))yeff,toowrreen 211T,99h7448e778SaamnnMddaRle11r99ae88np33dreww7see4ernr9eetsf00et..m7h7e77alreaaannetddmoo00p.f.l77ot55yh,,eerreeeosssbppwseeehccrtotviivveweedlolyydrke((aeaatdhvvsaaatlliuutnheeaesssiifgtgannucidiilffyiiitccypaaonnfptotullrylyaabbttieeloellonaowswotvttsehhirxee tmeehxxeoppneeetcxchtptseeeddcbterretaawdtteeesse))..n dcdTheeaahartetahhcSstseMriininRsaatirsscettspu.urddeyyTsheppinoostppsupulthlhaaeettniiorooanmnteibbonaaoossneef,ddthwooehnnoeddbreeesaaetttrhhvheerrdaoattvedeesseraaiiltnnhlsaaSninnMoonRna--seeitxxsuppsdoioygssnepeiddofpippcuooalpnpauttulliloyaanttbiieooolnvnooeowfrfstthsihiememieelixlxaapprreecctteedd cahtaerafcotearrissitimcisl.arT,hnisonp-heexnpoomseednopnop,uwlahteiroen,theis osvoemreatllimSeMsRrefisersriegdntiofiacantthlye b"heeloawlththye-weoxrpkeecrted eraffteecfto"rianoscimcuiplaart,inoonnal-exstpuodiseesd. pTohpeulsattiuodny, fiisnsdoimngestidmidesshreofwertrehadt tmoaalsetehmep"lhoeyaelethsyw-whoorwkoerr ked eiipnnrffotteshhcteeat"tPPeiFFncOOaonAAccecrppu.rrpooaddHtuiuooccwntteiiaovolnnesrtaau,rrdeetiaaehseff.oolrrToggwhrreeenaaustttmeeurrbdettyhhraoafinnfnd11pi00rnoygyseestaaadrrtsisedhhcsaaahddnocawaer33ts.h33(a--ftffooomullrdda)lieiinncectrmrheeiapassslgoeeryiioennuemmspomworatrhtakaoleliiwsttyyotrffhkrreoeomdm pFirondsitantges ctaenntcaetri.veH, aownedavelra,ttehrestloudwy nbuymtbheersoafmperolesatadteauctahnocre(rOsl(sfeonure)t ianl t1h9is98g)rorueppomrtaekdetshathteonly ofopirnnnoeeddoiuonfcfgttitshhoetnee.nffootauuAtrrivscceeaap,ssaeearssnaodtofefappsrltroaoustedsttyraoatstfeteuwdccoaayrnnkbcceeyerrrtshoocecaccsuuatrrmhrreeeedd3leiMinnadaaDeawwcuoaotrthrukkoreer,rr(OAddililrrsaeeebccntatllmyeyateeafnnlaggc1aai9lggi9eet8ddy)wiirnnhepPoPoFFrwOtOeeArAdethat only ppphrirroiigmmhdaeuarrcriittlliyhyoaneen.xxappAvooesssreeeaddpgaettororaiPPtesOOkosSSftFuFdd//ePyPaFFotOOfhSSwfoaarllrosksmooerbssslhhaaoodtwwdteeherddecaa3annMncooevDvre.ereracalTalllhtuillrso,owwwAaSSlsaMMbdaRRmtffauooorrftahaacllerlilleiccetayauucwssaeeshsseoosfowofdbeedsraeeeatrthvh,e,dbb,uutt aa chaauggirgaarhiiennenrtmmtetheaoaaxnnniiicannovggleottrghahiaagcttealtthrhieeesvkffiiidonnedfdniidcnneeggasstthhmmafataryyosmunngoogbttelsabbtdeesdrreteehrppaeectaaatttnhaacebbellbree.la((TAdAdhlleeiesrxxiaawsannaddseecrrdrueeitettaaetolla22tth00a0r0r3eg3)ee.)t.coaTTrshehgesearrnoeeboiisfssePrnnvFooeOdS, (3M 2003), current toxicological (3M 2003b). evidence that suggests that the bladder is a critical target organ of PFOS IIennma pallloaaytteeerrdssattutuddtyyheaattfaCCcoiolttitttaaygfgeoerGGrarotovvleee,a,stAAloleenxxeaaynneddaeerrr p((2200r0011o))itllohoooeokekeerndddaatot ftthh1ee99mm7o.ortratTalhliiettyyocoofhfo33r.,t99w99a22swwdooirrvkkieedrressd eeiinnxmttpoopolsttohuhyrrreeeeeed, eeaaxxntppdtohosnesuoufrraPeecFigglOirrtooyAuufppeossxrpbboaaastsuslereededa.sootnnoIttnhhseeehiiyorreuwwalrodorprbkkreiohhniriossttttoooerdrtyyh:t:ehdadeteen,ffdiignniioivttfeee1nPP9tFF9hO7eO.AApaTseehtxxeppeoocxsopsuuohrrsoeeur,,trppewrrbaoosybbaadwbbiolvlreeikdPePerFdFsOO1AA0 ePvPxFEepCCnoscciuoonrnntetth,aaeammni"idnnnaoanttoPiiooFPnnFOiiOAnn Attehhxeeepxoffpausccouiisrlluieittr"yey.gwwraIaotttueesprrh.ossuuuTplphdppellbyyre,,esnttuhholeettrreseedommfthaatayhyti,shhgaasivvtveeuednbbyeetsheehennopsswoaoesmmdteeetxeehpxxaoppsotoushseruuerroeevbeyttrooawlPPloFFrSOkOeMAArRs to efifovonrrcearnalellalinscceaathuuiensseep"ssrnoooosfftPdadeFteeaOattcAhhan((ec00xe..p8r8o55w))sauffsroocrro"btthghseereorwwuvopoer.rdkkeTiernrhsstehwwriaeasssluaaalttggesaraioisnntfutwwdheyeil,slllbsbbtuueetdllodyoewwasthtthhehselevfeeerxxdoppmteehccacttteeertddheberraratotoeevv..aesrNNacoluollaSrMR dinicsreeaasseewienrpercolsetavatetecdanincetrhewdaesfionbisteervPeFdOiAn ethxipsolsautrere sgtruoduyp., buOtndceeatahgsaifnr,omthecelroewbrnouvmabsecurlaorf cdcianaitssseeeerassposroeeftfwc.ceeeTrrraeeekbbererlonoevvvtaaaosstgceceudtulhlaieanrrr,tddhitiehsseeedaaerssefeesinuiilinnttestthhPoiisfsFtOgghrrAeoosuueeppxsp((tffoiiuvsvdueesr))emm(gatarhkkoreeuessep.dtthihOfeefnffeiricnenedndtiaingnfggaissinndtt,eientnnhgttaeasottilivfovewelaiangnnuhddmtddlibyiffefferiilccoeuuvfllattttteood interpret. Taken together, the results of these studies (three different findings of slightly elevated 222 22000099..00002233 ddeipissieedaaessmeeio--lddoigiffiffceearrleennfttiiinnndieenaagccshhofssttsuiudgdnyyif--ibbcaaassneecded.oonn ssmmaallll nnuummbbeerrssooffccaasseess)) ddoo nnoott rreepprreesseenntt epidemiological findings of significance. PPadFFuOOlSSs,,aPPnFFdOOcAAh,i,ldaarnneddnooittnhhteehrreppgeeerrfnfleluruoaorlroopccohhpeeummliaicctaaillossnhhaaatvvleeevbbeeeleesnnfrddeoetmteecc1tt/eedd10iin0n 0hhuu1mm/a1a0nn00bbollofooodtdhsosesereruusmmeeffnrrooimnm wawsdoaourmrkplktelsererasssn((fdOOrlcolshsmeeilnnsdireexettnRaaellidn2200tCh00re33ocscg,s,eOOndleolsrsnaeealnntpieeoottnpaaulcllea22nt00ti00oe3r3ndsd,a,atc33rlMeMovses22l00st00hf1e1rcocU)m)...S.lII,/nn1aP0aF0ssOtttuSouddycy1oo/o1nffc06e06n404t55roafaatddtiuhuolonlttsseddroosannenoeogrnredssineefrrurumomm `s<<ca44om..n1Icpepplnepptsbbraf(r(tottihhmoeensllsiiiimxmniiRtstoeeofrddfuedCmterewtoecestcrsiteiodonoon)bn)sattoetoirov11ne,,66dc55e6w6nitpptepphrbbs.a.agceNNorooofstsssuuhtbbehssetdtaaoUnnn.ttoSiira.a.,l PddSFiifefOfrefSureemrcneocPnneFcsciOeeinnsnAtrPPcaFFotinOOocnSSesn ranged tration from s ryrcaeaonannrggcseeeddnftrffrroaromtomimo2n3<<s11d.ii.n99f,fspeperpprebbunmtt0oswa55t22ee.r.3se3 pspopphbbbos.e.wrevAAdedpPprrFweeOlliitiSmhmiiacnnogaanerrcyyoesnfstttturuhdadetyyidoooofnnfsossrree.arraanSgffierrnroougmmmf55rP99oF99mOcc6Ahh.i7illtcddoorreneSnnc1e5aanggtpeerpsasbti22,o--na11ns22d yaPPreFFeaOaOrsAAsfhrccoooowmnneccde2en3nsttirdrmaaiitftlfiiaoeorrnnesPsnFrrtaaOsnntSgagtiieannsnggdsffhrProooFmwmOe<A<d11P..s99Fe22OruttSoom c55co66o.nn.11cceeppnnpptbttrr.iaa.ttiiAAoonnsssstturucaddonyyomgpoifnafcgreleldfddreeor1rmllyyt6pph.eee7oortppeolsltee51oiin5fn tttphhhpeeebSS, eeaaanttdtllee papPoroFeppOauuAlsla,ahttoiiaowonnndedttohhtasahtitmehhriaalpssaerbbrPefeFleeunnOosSsrtoutacdnhuiedemddPisciFsoaoOeflfasAdarirs((eOtOrhlulessmeegnnecnoeeettnracaalelln22pt00ro0a0p4t4)ui.l)o.antsTTihochnoeemissoopuuuarnrrccceleede((asstro)),oothbffueeetxrxpcepoosotussluoudrfreetihnttecooluPPdeFF.OOSS,, cAPcnooFannOlssyAuusmm,ieaseornr fdppbrroooltddohuueoccrtdtsps,s,eareemfnnlpuvvlioierrrosoonnccmmhoeleelnmnetctaiactlleadleesxxippinnootsstuhhurereeesgas,re, lonoyerr1oao9tlt3hhp0eeosrrpoofuccrlccaouutmippoaaantrtimiiooysn'nuaarlnlecceelrxxeupapiorto,sssubusrurheetosscw(o(3u3iMloMd Pi1nF199cO99l9u9S5cd)).e(. 3M Av11a99n9c9a99ul6ycu))sm..iscBBolooeftatbhhnleoPProFFbdOOasgSSasmaainnpnddlJePaPspFFcaOonO,lAAleichhntdaaeivvdceeaitbnbieenteehgnnethddeeeaetrtieelynccditeo1eodd9r5ii0nensnssvfaairmmorpmoplnleemasseromnoftfydidusruesascttrpuccooiottleslllneetsccihttaoeelwddsffonrurooromcPmeFhhOooofuSusse(e3hhMoolldd exposure (Morivak et al 2003). vacuum cleaner bags in Japan, indicating exposure (Moriwaki et al 2003). the indoor environment is a potential source of BbBlaaossoeedddsooennruaamnn,iimmianall ssptturudedliieeissmiaannnaddryaavvraeaipilolaarbbtlleienhh2uu0mm0a3anntheeeppiiEddPeemmAiiocolaloolggciiuccalalaltddeaaadttaamffoorraPPFFroOOfAAegxccpooionnsccuenernntetrra(attMiioOonnEss)iinn 2rbra0aln0on3gog)eed. ffsooeTrrrhuPPemFFM,OOiOAAn Eaffoopdrrreewwslcoiomrmmiiebneennasoryotfhfrcecehrhpieiollldrdattbbieievnaaerr2idi0nni0fgg3faeatrggheeeencaaEennPddbAeccthhciwialledldecrrnueenlncautooerffrdebbaneetttmwwmaeeereeagnnsiun66r66oefdaaennhxddup99mo,,sa11un22r55eP(((FEMEOPPOAAAE) Sd2seee0rvr0ueu3mlm)o. plleTemvveheenelltssMaaalnnOeddEffssedecetrersusu.mcmrillbTeehevveseerlltessheaddreereettelenarrumtmimviienenreeoddduifsiifnneuraanenncniiecmmretaaalblienssttttwuiueddesiieeenissncttsouourbbcreeehnacatassmlsscooeuccaliiaasatutteierdoedndwwsihiattuhhma aaaddrnvevesePrurslFsteOe.oAf intrathadaannetddvteiilhnnoettpeeymrrssmpepuneescctatiielebsseefddfiiieffncfftteeesrrr.eepnnrTcceehtesees,d,reddcoaoausrsteeeionmmuuesetmltryr.eiicrcossTuuuhssseeeuddnp,,rceaealnrnitddamiittnhnhteaeierccsyhhioEoniiPccsAeeuocorfheftpcthohareeltcaauannllaiismtmoiaoamlnlasmmyoaodshdeaaelvl;r;eeEEssuPePlrAtAiooaaufddsivlvniyitssreeas-s tutuhhnnaeddteelrtroheewessytteiimnmmdaauottsefetddtbhtteheheeinMssteeOerrrpEuurmmertaePPndFFgOecOaAtAuotocicooolunnocswcel.eynn.ttrIrTaanthtiieoornnpesscreeiinlnnitmttehhiveenaralrarauytatssEittPuoundAdoyyfruuetsspheeoeddrtrotoiaslksddoeeorrfmiivvPaeeyFtthOhheeAavMMeeOxOspEeEo,rs,ioummuraesaklkytiionngg tttahhhneeedggl8oee9wnn0eer0eraanlfldopprooovfppauturhlilaeaottuMiisooOnnt,,oExaair3c3aoMnMlgoegsscicticioeeaonlnttileiossntwtd((.pBBoIiuunnttetaen,rnhewhociofetfefnhetFttaeaav.ml1ae22lau00na00ot44if)o)ncc2aao1ll0fccuu0thllaeabttaeresiddsekdaa ooMMnfOOPtEFEheoOomfAfebbaeeextntpwwsoeeeseerunnurem11t66o0000 aPPnnoFFndOO-o8AAc9c0ccu0oopnnafcctoeeirnontvntraraaarltitloiioyounnsextiinopngxogesiecnenoederlorapaglelipocpopapolluepeolunafldattp3iio1oo0innn1tdd0saa,ttaw1a..5i5tFhF0ooabrramPPsFeFedOaOnSoS,no, f33P2MMF1O0hhS0aassbsaeccsaraellucdcmuuolllanetavettehdeleasdammMMeeOaOasnEEusrrreeaardnungmgieen ftfoohrer nhthhuouemnm-gaaoennncecppruooapplpuaultpilaooatptniiuaoollnnalyt((i3e3oMxnMpfo22r0s0o0e0m3d3beb)px.)e.poopW Wslhuehiroiellfee03tt1hhP0eeFt33oOMMA1M5Ma5nOO0dEEbPaccFsaaeOlldccSuuolalnaarttePiioFolnnoOsswS,ssuuasgggeggareuiesmnstttttlhheheeavrtteelttashhreeme hheieeanaashlluettrrhheednrritissiknkssthttoeo tuhnecegrteanienrtailepsoipnusluactihoncaflrcoumlateixopnso.sure to PFOA and PFOS are low, again there are inherent uncertainties in such calculations. `Summary of Environmental Data SPuRmOSmahrays obfeeEnnvdeirtoencmteednitnaltDheaptalasma and tissues ofwildlife from across the globe, including. srPseeeFapaltOlsis,Sl,eooshtta(teesGrrisbs,e,eseddyonolaldppnhehditiennKcssa,t,enadanqqauiunnaattti2hicc0e0bb1pi)irlr.dadsss,m,Tbbhaaaealldndredeesauatiglgsltlseseussoe,,fstpphoooilflsaawrrsibtbldeueadlairyrfsse,,sfhffrrrooeewmsshhtwwahacaattrtoeePrsrFsaaOtnnhSdde ssigsaalllowtobwiwdeaae,ttleeiynrrcffliiusshhd,,inaagnndd dreispttriliebsut(eGdieisnythaendglKobaanlneannvi2r0o0n1m)e.ntT.heLreevseullstos fofPthFiOsSstwuedryeshhiogwhetrhaintfPiFsOhS-cisawtiiadnedglypredatory distributed in the global environment. Levels of PFOS were higher in fish-eating and predatory =n 23 22000099..00002244 faaonnoiimdmaacllhssaittnhh.aannBiiannltdthheeeiairrgtltyyeppsiifccaralol mpprrteehyye,, MiinindddiiwcceaastttiinenggrntthhUaa.ttSP.PFFsOOhSSowmmeaadyythbbeiioohaaiccgcchuuemmstuulllaaetvteeelsaassoiiftt mmPFooOvvSeessiuunpppltthaheesma (f(luouevpoped1ltos0c2h2in,a,5i5tn77i.00sBsnnuaaa(nlnidooggerrlaaigavmlmeersss; ppufereporrmtmmoilit3llhli,eil6lii8Mtt0eerri)nd),,awaanennosddgtermmraniminnsUkk.pSffer.rroosmgmhroattwmhh)eee.dMMitChiddoewwnheeicssgtheteerennsrttUnlre.SvUa.Se..otlsssfihhoooootfwwhnPeeesFddrOttPhShFeeCinhhsiipggihlhnaeesssmtt a `wlwweiiivdllededllllsiiyffeiendisstsaaitsmmrspiuplbeleuests(,ei,ndss(uuliGccvihheeraas;ssyuePPptFFatOOolAA32.,,06aa08rr10ec)nttyayppniioccgaalrlallyymaasppppperrrooxxgiirmmamaatt)ee.llyyCttoeennnctteiinmmtreeasstillooonwwseeror faaonntddhaearrreePmmFuCuccshhinlfeessss widely distributed (Giesy et al 2001). BBHirrvooeraasdd,eearrnssdttuuhdduiieemssahnhaabvvleeoffoooduucnnoddllddeeecttteeeccdttaaibbnllJeeallpeeavvnee,llsswiootffhPPtFFhOeOSShiiignnhesssuu:rrfflaaeccveeelwwsaatotebersrses,,rvffieissdhh iaatnnhddebbiiwrraddtbbellroosooaddnaadnndd flfPiiivsFshehOrfsfSr,roolamenmvdehhlehesaauvivminillaayynquiibnantlddoiuuocssdttirrniicavaoelllirilztzeeeecddbterTTadtooeikknsyyaJooanpBBdaaantyy,wow((TTsiaatphnneiictyyhiaacesssuuhoiefegtthfaaeillsst2200lie0n03v3a)e).nl.sesoAAtbusddaeeerrccyvrreeeadaanssdiiinnntggthheggerNrawaoddraiitteehennrttSseooaaffndwas 2oPo0bbF0ssO3ee)rrS.vveleed3dvMewwlisiotthhpidnediarsisqattuatananectcdiaecePfifnFrroovCmmermtttaehhnbeeurfappatooecrrstttuaoornffidAAntngnwttpwowleaesrnrpptpe,,icnBiBeeAeslnlgogtiifwuuefmimrshp((VVinaannanddeeesVVtuiijajvvryeerraeenttdaaltlh22e00N0033o;;rtHHhooSfffefaeettwaalal.s. 2003). 3M operated a PFC manufacturing plant in Antwerp. cEEsasttpiimm(aaOtteeEddCbbDiioo2cc0oo0nn2cc)e.ennltSrrtaauttdiioiocnnsffoaafccttAoorrPssFffOoorr aPPnFFdOOPSSFiiOnnAffiishshhavrreaanneggseetiffmrraootmmed22t00h00atttobi11o,,g11o22n44ceiinnntbbrualuteeiggoinlilllfssacaatnnoddrs acabrraieeropcqqouu(nOiitcteEeCnlloroDwawt2e((101.8t0.8h2r)iio.nnufgSfahattuththdheeiaeaddsf ommooifidnnAnncoPhowFawsiO)ns.).(anETTdPhhAPeerFr2eeO0ff0oAo2rre)h,,aiivnnecceoonsnttitrmraasastttettdoo PFOS, PFOA does not that bioconcentration factors PFOS, PFOA does not bioconcentrate through the food chain (EPA 2002). `IInnTettnhhneeesUUsnneieitteeRddivSSettraattbeeosst,,h33uMMpsrrteersseeeaaamrrccahhneerdrssdccooownnnddsuutccrtteeedadm4aossfttiuutddsyyfoaocffilPPiFFtyOOiAAn aDaenncddatPPuFFrO,OSSAlllaeevvbeeallmssaiinn(Htthhaeensen ctal t2T2h00ee00n22)n8.)0e.-smsAAeinelnaealRlysyisevsciietssriooobfnofot44fh00tuwwhpaastttrereierrvaessmraammsauppndlldieeessdd.osshwhooCnwwosnetercddeeanttmhhtaarttaotlfloioiwotwsnsflleaeivcvneeilcllissrtyeooaffisnePPdDFFfOeOrcSSoamtwwuearer,nreeAaplpvarerbeerassaeemgnneoatt ttf(hHr3roao2unugsg+eh/hno-ouue1t1tt al tpp1haa1err4ttss8+0/pp--eemrr1it9tlrreiipllplslietiocondntioo((wppnnppstott))fruutehppaesmsit.rrsieveaCeamormonsoctfueftndththiereedaPP.tiFFCoCCnosommnacfanenunPuftrFafaacOtctiAtouunrrwisinenigrgnecffraabecceaiillsliieottydyw iftinrnhoDDmleeacabcanotruaaarvttettooorruaayagrnndeeaatovvefcee3trr2iaaogg+nee/-looiff1m l i t s ((f122e15c54ilpp+tpp/yt-).) 1uuT9pphspseitprrrteeeadlamoamotwiofvnfeslttthyrheeecaoDDmnese.cicasaCtttueuonrrntcffacaeccnioitllriinattytyci,,oebnbuusnttotaafvvaPeeorFtrafaOiggAeePoddFnwO33se9S9r44ea++nb//de--loP11w22F88OthppApepttfladodbuoonowwdrnnasitsonttrrrteyeahadmmTeteooenffctnttheihoesenseleimits RfRaadiicsvvioeelrirrtpysst.uuiggoTgngheetsesottrstteehhldaeaitttimvttehheneeltryr)eecaaaofrrnefesennicstootienssngiigtghnncieioffiniircccaaepnnnrttetrsrraeeetmnimocoonevvsaialnol ftmmhPeeeFccwOhhaaaStnneiai.snsmdmBssPo((FusslOuuaccAnhhgfaaeossruvvenotod.llaaalit.ntiillt0iihzze0aatt4Tiiooe)nnnsnooterrusdsieeed `aPPOdFFnstOOaorSSripoaat.innoddnPPPFtoFFOOsSOeAAdciomccnoocennencncette)nrntaatrftrafaiettociinootsinnnssrgaiinntnhgseseiiidxrxtifpeerereeonnsmewwn2aa1ctteee-rrin7ss0aathmmpepppltwlee(sasmtecceoroa.llnlleBec4cott3euedd+la/ffn-rrgo1oem8mr pel1ttJ.a)akkaiele.nFE(rt2rihi0eee04aatnn)wddostl1ul,aaadkkkieeeesd, OwwwhenhirtilealeerhiPoPi.FgFhOOPeAFAr OtcchSooannncccoetenhnntoctrseraeantttoiiroboansntisesornrrvasaenndrggaeeinddngteffhrdroeomfTmreo22nm77ne2--s1s55e-00e7ppR0ppitpv((pemmrt ee(uamapnnseta33rn99e4++a/3m/-o-9+f9p/-ppt)hp1e8t.).3ppMTTth)hfeeiasnsceeitlhcicetooynntcwiceneonnDtlterarcaaktateiitsoou,nnrss wOOdrnenigrgneokoiihinnnigggghwsseattrutueddthriie,eassnf((otcchooodooosrprerddoioindnbuaasctteteersddv,emmsdaeaiidinnnillmtyyhenebbtyyTs,e33nMMwna))esstaaserreeeweaddtReeesisrviigegtnrnreeeudadptsttmotoerneddtaeemttpeelrraommnfititnnhceeelPP3uFFMeCC,fccaoocsnnieclciweteaynntgtirernaatstDiiloouenndcsgsaetii,unnr daa20nnr0iddn2)kll.aiannndgdFffiowillullartlleeecraia,tccifhheoaasottweedhiipennrroaaednnuPuucFmmtCsb,bseesrareordocfifmmccaieitntniiuteesfss,aaawccctarrusoortsseesswdtthaohtreeerUUu.st.SreS.ed.a((t(mBBsauaetpttnpteetlllyplleelcai22nt00it0e0es00)f;,f;luOaOneEEndCCt,tDDwseo22wc00ao00gn22te,,rosEEllPuPcdAAigteie,s 2w0w.0ee00rr42ee1).iitnn0iiFtti5ioaa.ull2llry9ycpttiaatpirrebggseewttwehedidh.l.eerPePPFFPFOOFOSSCAscccooaonnrneccceemennnatttrnraruataifttoaiincoostiunnirsnnerdawwnaogasresttdueeswwfearadtoteem(rsr0uit.prre0pca4alty0tmmpceeipnntbittes{pp)0ll,aa2nan.tnt4d2eefftpffwpllubuo.eenncttIonnrradtarnnioggeleedcdditffirerosomm ctt0orr.ne0eca4aet1tmnmtteeronnatt5tip.p2oll9aannnsptwtpessbllruuweddghgfeeilrettohhmPeeFnPPOoFFnAO-OdSScetoccenooccnnteccnetenotnrta2trrt4aai4totiinopospnnbsrs.arrnDaagrnneiggdneedkdfrioffnrmrogomm0w.a000.t2.4e20rpppspppabbmbpttotoloe33s2.,1.14s222h00opwpppeppbbdb. aaImnnnadddxrPPiieFFmdOOumAA rPcPaoFFnnOOgcSeSednaatfnrnarddtoiPPomFnFnsOOonwAA-edccreeootncnfcecreotenmntttorrana5tot3iin.oo1-nndsspoepotfebfc00tf..ot00or66P233F4ppO4ppSpbbapaanbnn.dddDn00or..0in0n-22kd99eintppgcppebbwt,, arrteeess4rpp8ese.cac1tmtiipvvppeellbelyys;f;sollrhaaonnPwddFffOeiildAlll.mlleeaaaSxccuihhrmaafttuaeecme wraantgeresd rfraonmgednofnr-odmetneocnt-tdoet5e3e.t1 tpop0b.1fo3r8PpFpObSfoarnPdFnOoSn-adnedtefcrtotom 4n8o.n1-dpeptbecftotroP0F.O08A3. pSpburffaocre waters ranged from non-detect to 0.138 ppb 2% for PFOS and from non-detect to 0.083 ppb for 24 22000099..00002255 fPPoFFrOOPAAF;O;Ass.eeddiimDmaeetnnattssfrrraaonnmggteehddeffcrrooonmtmrnonloonncdi-tdeietetcseccwttert0oe 11g..e11n33erppapplbblyffoaorrttPPhFFeOOlSSovaaennrddeffnrrdoomomfnntoohnens--edderetaetncegtecttsoto, 1w1.i77t55hppappbb efffeogewrewsP,eeFxxbOccreeeApapt.dtii,ooDnfnsias.st.ha,MMfaroonordmreegttrthhhoeaaunncnod22n00bt00reoefflfoo)cooiwddtieepprsrreoowaddeuulrccoett gcssoeaalnmmleeppcrltaleeeldsls.y((gagPtrreetFeheOnneSbbloeewwaaannesssr,,oeaannppldpyplloedesfes,ft,heppecoostrreekkd,r,iammnigilflekiksv,,,eccwhshiaiictcmhkkpeleanen,s,, (ge(oagrnngaeesm,gg(brrnrooge/uuaenn)d.dd,bfbeiOesenhefl,fayaannnodddnegffooorfouururtnmmhdieillbkkfeoessuafar)mmmpwpilleeleksrse))s.,aalaamsttpolaacemmosalalwxexaciismtmeudfu.rmmomPccFooanOncccSeoennnwtitrraoaaslttiiocooninntloyyo,ffdw0e0i.t.te88hc55t22tehdnenaairnnneoomfgigavrrieaanmmdsaessmrpppfeerlrreosm, sgsfuuriappomppmllyyc(onccngiit/ttrgieeos)sl...iOtPPenFFslOyO,AAownwwoeaaosbsfrddeteheatetdeesfccoatteumeddrplmaatetislcckoo(nnsfccaoeemnmntptrrloaeantsteiiowocnnaossnstuufrpprooltfmooa22na.d33.c55sounnnptggpro//lgglyciicninitytttwi,ewwos.iggtthrrwootuouhnneaddprbpebelmeeeeafsfisnasadmampemplrpleflsereossm (supply cities), and from control cities, (supply cities), and onetwo one green bread green bean sample froma supply city samples (from one control and supply bean sample from a supply city. cities), two apple samples "wTTihhdeeesaapvvraaeiialldaa.bblleeHdduaamttaaanrreesggamarraddyiinnbggettheheexppporrseeessdeenntccoeePooFffCPPsFFCtChssroiinungtthhheenueenmnvevirirrooounnsmmepenanttthsswuuaggyggseessattnttdhhaacttottmhhemeyyonaarree activitethse exact routes widespread. Humans may activities - the exact routes and exposure be exposed to and exposure concentatiornesnot currently known. PFCs through numerous pathways and common concentrations are not currently known. PPEllRaaGnn.nneeoddnAAbcctteiioohnnssoaf3lMf, has proposed a workplan conducting afaciliy-wide investigation of PFC. releases at the site (ERG 2004). The ERG, on behalf of 3M, has proposed releases at the site (ERG 2004). The purposeofthe workplan a workplan conducting a purpose of the workplan is to:facility-wide is to: investigation of PFC DwDeaefsfitinneeeditthshepeoeesxxatlteenpntrtaaacnntiddcemmsaoaggfnniPittEuuCddsee;ooffoonn-s-siittee contamination contamination resulting resulting from from the the past past site site + + DweafsitneedtishpeohsyadlrporlaocgtiyceasndofgPeoFlCosg;yof th ste and the potential rouesof exposure; and PDreofvinideethienfhoyrdmarotlioognyanandddagteaolnoegeydeodfftcohoenssiitedeanrdatthieonpoofternetsiaplornosueteasctoifoensxposure; and Provide information and data needed for consideration of response actions. "dTTihhseepowwsoaolrr,kkpiplnlaacnlnuiidnnivvnooglllvveeessastthheeesccooollllteehccettiieoonnnvooifrfhoihnsistmtoeornrii,ccaaslluiimnnmffaoorrrmimcaaittniioogannloolnnavPPiFFlCCabpplrreooddiuunccftotiiroomnna,,tuiuossne,,raaenngddarding `gdgrrirsooopuuuonnnsdddawwwlaa, attitneeecrrrlumfmlodooninnwigittmoororrediilneenlgag,saaeannsnddtdoppcrrtooholdedluueecccntttviiiooiornnnowonwfmeelglelsrnsotoo,unnnsduttwhmhaeemtsseiairttre.i.szainIImttgpaallalesslsolo afiivonnravviooPllalFvvbCeelessapipnnrrafeeloppyrasamrirasaaftttriiioooonnnmoaorfeflgaaawrdelinlsg ougosnnroittnuhhgneedpsswuiisttaeh.t.-eprAArfolffobuuewrrstthmhieenorrdlssoettcel,apptaiwwnoidinllslcwbboheelleet0rocetccioooPnllElleCoecsfttgwggrerroorouueunnnduddwswweaadattteeoerrrrsdssaiaamsmmppppollseleeesssdf,nnoeareanrPrdFttChfhieenaaMMnlilasiylssyspisirssiessspiifpaprrppoaiimtRRiioainvvlleeorwr faells summary report, using push-probes summary report. in locations where PFCs were used or disposed, and finally preparation of a (EEEPPCAA'A's)s OOpfrffofiiccceeessoouffndPPoeolrllltuuattikiooennnwPPirrteevvheenvntatiirooinnouaasnnmddaTnTuoofxaiicct,su, rtthehrrrosouuaggnhhdaaunnseeernnsfotbofrrccPeeaFabbCllsee c(cioonnncssleeunndttinaagggrr3eeMee)mmeaennntdt o(oPEttFhhCOeeArrA)i)innpttierenorretechssetetseeseddnuppvnaaidrrrtetioireentssam,,kehehnnatsswabbseiesteheoncnvissaatttruuiedoddyuyiwsiningmtghathnhteheuefeeamxxctatteenunnurtetf,,radsdicisatstnutrrdriib,buuusuttesiiorcos,nno,,odaafinnPsddFpCoffatssteea(lioonoffcflPPuFEPdCCFinsCsgs((pp3orrMriimm)PaaaFrrinCilldyy cPcEooFPnnOAttaaAiwin)neiiinbnnggsthpptreeroodedu(nucwvctwistnrs.ov.n.eAmApllealln.ddgtoooaccvsuulsemmodeceoninacttktsesedtrr)eewllauaitttnehedddethrttoeodtmtohhciiakssneuuutnfnnaddcueetrmrutbtraaeekk,riinunOgsgPePaa, rTroee-r2ppd0ooi0ssst3ptee-odd0s0aeal1nn2odd.faaPvvaFaiCillaasbbollere PooFnnCaann EImInnoPtntAhhiitiswsorEEeibCCnAgAsitieppnrrt(oowhcceewessvswis,c,.ieEEnpiPPatA.Aygooiifdvde/efennadcitiioiflfciieetkdideetsss/ee)cvvuueernrreadanlletrnnledeyeoddmcsaskneffuotofrrnaucmmtmoounbrniieittnroogrOr,iinPnpggProTiicnn-ef2fsoo0srr0immn3aag-t,t0ii0ooan1nn,2,d.iiunncsclliuunddiivnnaggrious mPPprFFooCCncssei.t.sosrTTihhnhargrveeeieenicctnohodmmeipvpcaiaancntiiineeeaidssty---woi33fMMlf,a,lcDDiilyiyntnniecgesooonnnceeun((rasaerer3s3nMMtliyncctmooommaMpnpeauamnnfoay)rc),ta,unaardinnnddag,DDofpuurUPPonocodnenestr-st-sintppgaaa,nrrdttaiiinccndiigppuaa(tstiMiinnnOgggUiiv)nnarttwhihoiiitssuhs the pEElorPPcoAAacteeffsdoosrrihnmmaovDoneenicitiatnotodruririicn,naggtAeooldnnaabaaannwmddialaalirranoonguudnnneddWsasttshhtheoeiiirnegnrrteetesosprpnee,icnctWttiioevvseM etffelVlmuiuoroogrrrioaonpinpoaod.llayymom3efVerr0U/mmnDadaynennurucfsfaotaacncnttdauuinrrndiignnEgg(PMffaaAOcciielUlxiitt)eiiecewsusittehdthaen MloOcaUtedoninODcetcoabtuer,25A,l2a0b0a4m. aAanfdouWrtahshcionmgptaonny, ,WDeasitkVinirgAimneiar.ic3,Mi/sDuynndeeortnaaknidngEaPnAinedxeepceuntdeednta,n MOU on October 25, 2004. A fourth 2 company, Daikin America, is undertaking an independent, 25 22000099..00002266 voluniary moniring program at ts uoropoiymer manufacturing facility, which is co-located `wviwnoiictlthulhunttdthhaeeerdy33iM Mnm/o/hDDinyiytnneocferfioononnrgtppp1llraaonndgttariiatnnmbDDeeaecctcaaiatuttsusurefr,l,uiAAolirlaaonbbpoaaommllyaaom..ngeTTerhrhmeepar33noMuMdfuac--CciCtonutogrttitnPaagFggeeOfaAGGcrirlooointvvyee, wffcaaochcmiiilcmliihettyyricshhiaacassol-nnlboooatcsabbitseeeeednn ((ifnMoMrc..lFhFu..edeDD3dooMmmii/nnDitnihyiainaskkc,e,ofEEnfoPPprAAtl,a,tonppteedriransstooeDnnebaacellactccauoourmms,memuAinlutianicsbiacantaomitiaoolnoni,n,ngv22eo00rl00v4p4)er.)so. dtThTuehchiefenogpplhhlPaaoFsswOeeiddAn--aa(oppinppnrranoooaacccophhmarmmmiooencnriucitltioorarlroiibnrndaggesrpips:llaann fWberstthoen32M00/D4)yneon plant in Decatur, Alabama involves the following (in no particular order; Weston 2004): ++ MMMoononinittitooorrriiinnngggooofff ggsurrroofuuanncddewwwaaattteeerr,wwesleellsldsimaaennnddtspp,llaaannqttuaeetffifflcluuoeenrntgta((nooinnsaamnnsddaoonffdff-sfsiiitstehe))n;;the adjacent + TAM TieeronnnndnieietssospssreeeirneesgiRRoioinvvfeemsrruo,;rdfealcienwgoatferP, EsCedeimmiesnstiso,nasq;uatic organisms and fish in the adjacent + ASASoowiirielldlssilaasmpmsepuprlrlsiviinneoggyn((imoonnnothdaaeennalddrineoogaffofof-fifsicPtte)hFe);C;pleamnti;ssions; ++ SSASaaammwmppepllllliiinnnsggguoroovfffettytehhrieerneDDstetherceciaaaatltruuevrraewgwoeaaftttateehtrreissopunulppaappnnlltdyy; avaennrddcwwbaraas~ttteeeswwa(atotenerrattnrredatotmmfeFesnnittt)pp;llaaanntntdeefffluueen;t; + Monitoringofaquatic avian biota (on and offsite). Sampling of terrestrial vegetation and vertebrates (on and off-site); and Monitoring of aquatic avian biota (on and off-site). t"TThhheeeE33PMMA//DDwyeynbncseiootnneMM(OOwUUwwweiitpthha EEgoPvAPi,eadaAoswcwek,leetlll)aaussnttdhheeerffudlolllcetkeexxttt noofutfmthhbeeermmnOoiPnPtiToto-rr2ii0nn0gg4pp-ll0a1an1na2ar.re lloSoccoaamtteeeddooofnnthe "tpphTrrehooeppErooPesssAeeuddlwtmmseooobnfnitstihitotoeerrii(snnwtgguwdhhiwaaesss.eaawplilarlre.legaaobddveyy/epbbdreeooeevcnnikdcceeootdfnn)ddtuuoucnctEdteePeddrA,,dwwwoihcittkehhenoottctnhhoueemmrrplwwbeoeotrrrekkOd.pPprrPoSoTippm-oo2issl0eea0ddr4ff-moo0orr1n1i22t200o0.0r44iSnaaognnmdde22o00f005t5h.e (T(piirhnnoeccpllruouesddseiiundnlggtssaacoiiorrfpmetmhoooenfnitsitthtouoirdrsiiinenmgsgonwffiooitrrlolPPrbiFFenCCgpss)r)polhhvaaaindsseibbsdeebeteronnoEappdPrreooArppaotwshsheaendedntffhoocerroosmotctphhoeleperretePPpdFFr.CoCpSommisamaennidulufabfaryacmctEtuouRrnriiiGntnoggfriossnriigttetssh..e 3TThMhee- CpCforaootctptiaaolggsieeesdGGirsnrcootovvepeeremffoaasccfioiltflithittihyys.e. mDpDoruunoeeidtuo0tocrtinbbiuguosnspiinqnlaeeunssassnisiddatabtetraaosappodrrfieivvrPaaFtcchCyyasnccoortnhnececeenrsrocnntoss,p,aevtthahpieelroarrebepllloaaesttieifvdvreeobmssyiiz3zEeMssRo.oGffHtftohohweeretttvhwweeoor3,M - `tfhhaweecarrisleeittaaiderriesespimmnoasatannelyyr,maadsppippsoacafrhrteaehnrnetgtepSsriioommfidilPulaacFrritCiittoiiecenssoqniitunnaattinenetririmtnmigessswooaoffsofotvPveeFesrraC0alslll aPPrmFeEaCCnjoopptrrraoowvddauautciceltatriiboowlnnae,,yfssr(iiotttemehlla3TayyMeoonu.untte,,HspposaaewssetevooRnein-rv-s,seiirtteein (wDD4eae0csc+ataettyuuderraisarapsnnoddastattDhlhe,eecdMMaisticiusshsriaiasrsgnsiiedpppopaifsRRPmiFaivvCneeyrrcaiionsnnCCt5aooi0tntttiyaanegggaeerwsGGraarostotvevCeseo)),kt,oaaaganneddmGttahrhjoeeovrlelew)en.naggtttehhBroawofsftaeytidiomm(tenehtePPhTFFeCCseenssnwfweaescesrtreoeerespp,Rrrooaivddeuurcceeindd s(spi4irmm0oip+ilelaaryrrl,e,yapprahhssaasasseteesDdds estscchcaeootppupeeortooaefnnftdiiinnaavvlseesismtmtiiapggnaaacytttiivavoesefd5wwe0oocryrakkedafferoossrr attohthfeeCP3o3FMtMtCag-p-erCCooGodtutrttocaatvggieeeo).nGroaBronvavdseweeadsssiitoteenmmdtihaaseyypseobbseefaalnnc.eetoeerddSseeo,ddmaettoo apaMssrPppoeepCccetAtrssloyhofaafssthshaeeelssoDDeteshccaaeatttpeuuodrrtewwtnhooatrtirakkPlpplFilmaaCnnppammrcaoatdyyoucfnntooditteocbbnaeedwaaaeppsspptoielifcscaPafbFbrilCocempt1o0trohttedhhueeCcoCCttiotootatntgaaeaggneeGdrGGowrrvooaevsvteefeaffcdaaiiclcsiiilptliioyttysym.a.al.yTThhSheeoamvee M bsboee,PeenntChAddeiiesshppaioossssaeaedldpsaooatttesonottattihtheaeedlrr ftkkhonnraootPwwPFnnFCC33MtMsporowwhdaaasuvstceteetiaoddfniifssepwpcootasessadatlelvsssaiirfttrieooesmuiisntmhtthheeeedCTTiowwti(tiasnnogieCC,iiGttgiirreeoossvuaanerrdeefwaaaact((iMelMirtPy,PCComrAAasy22u00rh00fa44vc).)ee. If If swoa,tethr)erienitshaespeolteoncatitailonfsorasPFweClls.to have affected various media (soil, groundwater, or surface water) in these locations as well. C'ChAhiTillSddDHHReeaaalnlttdhh MCCoDonnsIsiiddreeercraaottgiinooinnzsse tht the unique vulnrabilies ofinfants and children make them of ACSspphTeieclcSidiDaarlleRnccooaannnrccdeeerMartnnDgttorHaccrtooememcmomruginusniknitzitiethieeatshsnaffataadctcuheeleddsuwwfniirittqhohumcceocovennrutttaalanmmieinirnnkaaabittniiilodoitsnnieooofsfefoxtthfpheeoilnisrrfuawwrnaaettsteserart,n,odsohoicalilh,z,ialaardiirdrr,,eonooufsrmffsoaouookbddes..ttahnecmesof Caoatfthtwwielanadssrtbteereniddnaiigrsseppfoooasostadagllrisesniiatttoteeesc.r.orTTnihshtkeaeymythiaanarraneetaemmddrouarleretesallfsiir.kkoeemTllyyhcet0oeyrbbtaaeericneesxxkmppianoolsdsleeseddrobbfteheeaccxnaapuuoassdseeuultrthhsee,seyytwopphlhliaaacyyzhmaoorueudtatoddnuoossoorrsshsuebaaynsntddantthcheeeysy often bring food into contaminated areas. They are smaller than adults, which means they 2% 26 22000099..00002277 bbhriregeahaetthrheedddoususestst,, oosfoiclilh,,eaamnniddcahhleeaaevvxyypoVvsaaupprooerrpsseccrlloobssoeedty0o twthehieeghggtrr.oouunTndhd.e. dCCehhviielllddorreepnninaagllssbooodwWyeeiisggyhhstlleeessmsss,, roreefsscuuhllittilindngrgeiinnn chciaamingnpsho_urestsuratsdnatatoiilsnnye,sppceeohrrfmimlcaadhnnreeeemnnntitdcddeaaapl memenxaadpggoeecisouifmfrpteoloxepxiteiccerlbeeyxxoppodonoyssauwudrreueeilssgtohscotccf.ucoTrruhrdreidusurdkrieiinvndgeeglnotcciprrfiiittiniiccgcaaatlbliooggndrryooawwnstdythhsmtsseatamnaggaesesgo.se.fmM Mceohnoistlstdtren decisions, housing decisions, importantly, children depend decisions, housing decisions, and access completely and access o medica care. on adults for risk to medical care. identification and management BuBneelcciaakuueslsyeetttohhheeassviitete biiseaesanesceecuxuprroeescechhdeefmmoiicPcaFallCpsprraooddutuchctetiisooinntaainntddselwwfa.asstTteeheddriiessppaoorsseaalcluffraarcceiinllitittlyyy,, nccohhiidlldadtrreaennavaaarrieelvvaeberlryey 0 doudefnettlPeiekFrrmeCmlisyinneeteoxiitfhfecacnhvhdieielldddbrreoeeefnnnf ccteoohxuuepllsoddtsheehdaapvvrteeoopbbPeeeFreeCynn,seecaxxhtppiotolhssdeeerddesnitttoeowhiPPtosFEeCClmfss.aooyfTfffhhoaeofrvfetethhabeereeessicinttueelrirppevrrinoontppgleyerirnytny.oa.rdeIIaaFftsaaaibirraeveeyammoiinlsiasdsbsiiltoeohnnestso. stosiihfttreePoFbbuooCguhusnndoedtaxahrtreieireenssedneccvdooiuuorllofddfnmhthheaaenvvteesaibltbeeemeepennrdoeeipxxae.pprotoysPs,eeFddcChswwilhhdhiiralleveeneppwbrroeoheddounucmcdttiaieooytnnehcwwaeavadses iboonceccbeculnurorrolriiidvnniggsn,a,gmoopirrnlcceaoosrouueflladdschbbbieeelyeedoxxrnppedoonssteefhddreom atleast 23 different sates. through other environmental at least 23 different states. media. PFCs have been detected in blood samples of children from IIVV.. CCoonncclluussiioonnss G"TTrhhoeevppeoottfeeancntitiliaialtlyiicmapmnancopttsoabonenpcfupubtullblilsiaccsshheeeasalslttehhd ffbrryoomMm DppeeHrrffllautuootrrhooscchhteeimmmieic,caabllerrceeallueesaaesseetsshaaettetthhaeere33nMMot--sCCuofofttittcaaiggeeent esGeunnrrvvofiivarreocoennfmmawecaetninletitrtaay,ll csddaesadnttinaamoaaetvnvbataiesill,aafubballnlleedyrrbaeeisggostaaearr.sddsiiennAdggtbPPhyFFiCMCtDiiimmHmppeaaacpcttettssrhfiffsrlroutomiommrttoehhc,eehbeffeiaaccccaiiaullliistteyyretiihlnneeassrsoeoieilsal,,rfeggrrrnoooomuutnntsddhuwewfafstaitetceerire,,nt srrgeueeppnrfreraeercssaeeelnnwpttoaaaptnnuelrii,anntsddieeeodttneiemrrimmseiiennnxtaaspt,toeeasnppeduudbbbltliioioccPtahhF.eCeasaAl.lttthhtPhhhaFaizsCzaastrirhdmd.a.eveTTphehearefrrlleeuooniisrgsoahchllaaeccmlkkifoocefafliiinnrneffholoeurrammmsaaaetntsiisoofnrnaonmaadbbooatuhunteit mhhsaiootlwewsttthhueeds indicatea potential general population indicate a potential for toxicity to the fiver and effectson reproduction and developmen. is exposed to PFCs. PFCs have a long half-life in humans and animal for toxicity to the liver and effects on reproduction and development. studies V. Recommendations V. Recommendations 1. 1. CwCooonrnsksiidtdeheraratattiiisoognnenssehhrooauullllddysbbieemiggliiavvreennttotoothddaeetvvdeeleloovppeiinnlggoaapnnbeddydiim3mpMpleflmoreentmhtieengDnaeatcassitccunoorpp,geeAoolffaiibnnavvmeesasttiifggaacaittliioiotnny ounwufndotderhekrerttDhhheeaeictiraristppugrrroeopnwpoeoorssraeeklddplylvvasoonillmuumnnialttaaayrrrynytooaattgghrbraeeeteeadmmpeepevnlnetitlcowwapibitelthhde tttbhohyeet3hEEMePPCAAofot((rtssatechgeeeeppDGaarggeoeecssvaet22u33fr.-,a22cA4i4)l)l.i_atby,aSSmsooommaaeefapaachssiappliseetecyctdtss atoahppfeppthrreooexaatDeccnhhetciiasotfrrueePrccEwooCmmomrcmkeopennnldtadaenmedid.mn. aaytTTihhnoeeontddfbatretaoamafrprtoophmlemicfassaubcuiclclehhittaaoynnithniinenavvlCeessomttteiitgdgaaiagttaeii,ooGnnarnaaodrrvteeeonnfaeeaseecsddieleeisddtsytt,oiossouupnnaoddtepeerhrnsstattisaaaenlnddd 2. tii3hmmMeppaeascxchtttoeouonlnntdoppcuufobbPnllFiticciCnhhuceeeoaatntlhtoth.at.makineaatciotinonfrtoomenthseurfeactihlaittywoinrkaellrsmeatditah,eaCnodtttoagaessGersosvietsfpcoitletnytiaalre 2. 3noMMotDt eHesxxhppoHoousIsldeeBddcott(oonctuPPirnFEruCCeenssttltothyhrtoabokeuuieggnhhagcttithhimeeopnfflaateccomiileleiintntytyseuwwdraeatbteteyhrra3sstMuuw)pp.poplrlyykeaartts concentrations at the Cottage concentrations in excessof the Grove facility are in excess of the 33.. M W WinhsDhitilHaleelaHrrteeiBlloeeVnaaosssfee(sscGuooAfrfrCPPeFnFtCtClrsyesabtttooemiettnhnhgtee,iMMm3isipMsslsieissmsshsioeippunplptideidRcRoibinvvyteeir3rnMaaurre)ee.tnnoooiwwdebbnteeiiinfnyggaggneednneerrreaadllullycyepp(rroeervveelnnittmeeiddnabbtyyetthhee ewiwnnhhsveteiarrrleeloappntoimoosessnsniitbbollffeeGr))oAaamnnCtyyhtooerttefhhaueetcmrrilppeoyont.ttee,nn3ttiMiaall soohnnogguoolidinncggoddniitssincchuhaaerrtggoeessidooeffnPPtiFFfyOOSaSndaannrddedPPuFFcOeOAA(orttooetlthihmee inate 44.. eIpInnrnfofvocoirrermosmnsaaimttniioegonnnwtassfshhrtoooeuumlslddtfhbbreeeomfggaatacthtihhelieetiryrtee.eddwbbeyyre33dMMisrrpeeoggsaaerrdddiininggntaahnneyypooaffsff,--ssaiitnetdlloaocpcpaarttioioopnnrssiawwtheheesrrieepPPsFFsCChould be aken to investigate possible PEC releases from those locations. processing wastes from the site were disposed in the past, and appropriate taken to investigate possible PFC releases from those locations. steps should be zn 27 22000099..00002288 VVII.. PPuubblliicc HHeeaalltthh AAccttiioonn PPllaann M aMfDDf'Hos'ns PtPhuuebbliliinccveHHseteaialgltathhtiAAocncottifioonnPFCPPllaanrnelffoeoarsttehhseeasstiittteeheccoosninstsi,isstdtssiosotffrcicobounnttitiionnnuoueefddthccioosnnssruuelpltotaartttii,oopnnowswsiiittbhhleMMPPCCAA asadtdaddififttiiooonnnaathllepprriinivvvaaettseetwiwgealetllilossnaammoplfpiPlniFngCg,, raaennleddappsaearsrttiiacctiiptphaaettiiosoinnte,iinndaaisnntyyribppullatainnonnneeddofpputuhbbilsliiccreoopuuottrrrtee, aapccohhssaaiccbttliievviittieess.. PPrreeppaarreerrssooff RReeppoorrtt:: JJHaaemamleetsshKKAeesllsllyey,s,sMMo.r.SS.. HSSMiiiettneaenlAAtehssssosAeetsssassseDmmseesepnonatrtraatnnmddenCCtoononsfsuulHteltaaatltiitoohnn UUnniitt tMel:in(n6e5s1o)t2a1D5e-p0a9r1t3ment of Health tel: (651) 215-0913 VVHiyirdrggrioinngiieaaolYYoiignniggslltiinngg HSSMiiiyttneednrAAeosssgsosceetossalssoDmmgeeiepsnnatttraatnnmddenCCtoononsfsuulHteltaaatltiitoohnn UUnniitt ttMeell::in((n66e55s11o))ta2211D55e--p00a99r11tm77 ent of Health 2288 22000099..00002299 VIL References VII. References 3M1999a. TheScioefnOrgcaneic Fluorochemistey. 3M Company, St. Paul, Minnesota. FF3eMebbrr1uu9aar9ryy9a55., 1999. The Science 1999. of Organic Fluorochemistry. 3M Company, St. Paul, Minnesota. 3M3iMMn1n9e19s9o99t09a.b.. FFMlleuuyoorro2o6cc,hhee1mm9i9ic9ca.all UUssee,, DDiissttrriibbuuttiioonn,, aannddRReleleeaassee OOvveerrvviieeww.. 33MM CCoommppaanny,ySSt,.t. PPaauull,, Minnesota. May 26, 1999. T33oMMxi11c99o99l99occ.g.y PPDeaetrraff.lluuoo3rroMoooccCttoaamnnpeeaSSnuuyllf,foonSnatat.teeP::auCClu,urrrMreiennnntteSSsouutmmam.maarJryyanooufafrHHyu2umm1,aann19SS9ee9rrs.a,, HHeeaalltthh,, aanndd Toxicology Data. 3M Company, St. Paul, Minnesota. January 21, 1999. E33nMMvi22r00o00n00m8a.e.ntCCaolorrrPrreeosstppeoocnntddieeonnnccAeegeffnrrocomym.W WiJilulllniieaamm16AA,..2W0We0pe0ppnpenre,r, 33MM CCoommppaannyy,,ttoo CChhaarrlleess AAuueerr,, UUSS. Environmental Protection Agency. June 16, 2000. a33nMMd202V00a00r6i0o.bu.sVVSoaolllutunnFttoaarrrmyysU.Uss3eeM,aannSddt.EExPxappuolo,ssuuMrrieenInInenfsfooortrmam.aattiioAonpniPPlrroo2ff7illee2--00PP0ee.rrfflluucorrooooccttaannee SSuullffoonniicc AAcciidd and Various Salt Forms. 3M, St. Paul, Minnesota. April 27, 2000. 333MMW1,220S0t0.000cPc.au.l,VVoMoliluunnnntetaasroryytaUU.sseeJuaannnedd 8EE,xx2pp0oo0ss0uu.rrse IInnffoorrmmaattiioonnPProroffiillee -~ PPeefrflluuoorroooaccttaannooicc AAcciidd aanndd SSaatltss.. 3M, St. Paul, Minnesota. June 8, 2000. M3EfM2fe0c2t00s011.3a.M,SSuuSlil.ffooPnnaaauttee,ddMPPienernrfefllsuouotoraro.occhheMemmairicccaahllss1ii,nn20tth0hee1 EEnnvviirroonnmmenetn:t: SSoouurrcceess,, DDiissppeerrssiioonn,, FFaattee aanndd Effects. 3M, St. Paul, Minnesota. March 1, 2001. 3P3oMMl2l0u2t00i10oblnb.P.reCCvooernrrrteeissoppnooannndddeennTccoeexiffcrrsoo.mm AMMuigiccuhhsaateell1,AA.2.0SS0aa3nn.ttoorroo,, 33MM CCoommppaannyy t(o0 tthhee UUSS EEPPAA OOffffiiccee ooff Pollution Prevention and Toxics. August 1, 2003. T33eMMpe22r00,0013clcM.. CIIoddmeennpttaiiffniicycaattMiieoodnnicoofaflffloDureooproacrchthemememincitca,allSss.iinnPassueelrr,aaoMofifnhcnhieisllodrtreeann. iiJnnuttnhheee2UU5n,niit2te0ed0d1SS.ttaetse.s. Interim Interim report, 3M Company Medical Department, St. Paul, Minnesota. June 25, 2001. O33fMMfi22c0e0003o38fPa.o.LllLeuetttiteeornffrrPoormmevMeMincticihohanaeelalAnA.d. STSaoanxintcotsor.roo,,A33uMMgu,,saatnndd1, GG20ee0oo3rrgegHeH.. Millet, Millet, 3M0th,e Us, 3M, to the U.S. EPA EPA Office of Pollution Prevention and Toxics. August 1,2003. S33aMMlt2s.02000333bMb..CoEEmnnvpviairrnooynn,mmeSen.nttaaPlaluaalnn,ddMHiHneenaaellstthhotAAas.ssseeAssussgmmuesennttt2oo0ff,PP2ee0fr0fl3luu.oorrooooccttaannee SSuullffoonnaattee AAcciidd aanndd iittss Salts. 3M Company, St. Paul, Minnesota. August 20, 2003. AApebbreef,uT,To..raianantddeNNdaagogaragssaeen,,iScS..c119o98822m.. pEFlleeooccttfruroiocncndhhueesdmmiiriicscaaalll ffilnlutoeorrrieisnnta.attiiIoon:nn((BSSaiinmkmsoo,nnssRPPEr.orcdeoisso)rca.asseaaPrsoreouputsateaet)it0oon. pppSrooeronprfsepl;reutro1itri9eei8sns2,a,.ataenndpdd. oii1rn9ngd-da4uun3ss.itctriacalol maapppppolluiicncadattsioionofns oforganoflucine industrial interest. of organofluorine compounds. New York: In: Banks, R.E., editor. compounds. New York: John Wiley Preparation, John Wiley & & Sons; 1982. p. 19-43. (AAullneepxxuaabnnldideserhr,e,dBB).H.H.. 2001. 2001. Mortality Study of Workers Employeda the 3M Mortality Study of Workers Employed at the 3M Cottage Grove Facility. Cottage Grove Facility. (unpublished). Alexander, B.H.,Olsen,G.W,,Burris, JM, Mandel, LH, and Mandel, LH. 2003. Mortality of Alexander, B.H., Olsen, G.W., Burris, J.M., 2 Mandel, J.H., and Mandel, J.H. 2003. Mortality of 29 22000099..00003300 eEemnmvppillroooyyneemeeessnotofaflaapMpeeerdrffillcuuioonrreoo6oo0cct:taan7ne2cs2su-ul7pl2hp0ho.onnyyi fflluuoorriiddee mmaannuuffaaccttuurriinngg ppllaannt.t. OOccccuuppaattiioonnaall aanndd Environmental Medicine 60: 722-729. BsBeaandderrs,,cMMen..tZZ,r.,aaasnnbddyBBtiihrernnbbpaaeuurmmo,x,iLLs..oSSm..e22p00r00o44l..ifEeErnnahhtaaonrn-ccaeecddivppaoottteeednntrtiieaaclleffpootrrorooxxailiddpaahttaiivvaeegotsntrireessstsspiieanrllliiuvvoeerrrossooocfftanoic acid. Mechanismsof Ageingand Development 125: 69-75. senescent rats by the peroxisome proliferator-activated receptor acid. Mechanisms of Ageing and Development 125: 69-75. alpha agonist perfluorooctanoic BABraaerraers,11993991M1.. ChRReeemmmoelediditiaaellCIIennnvvteeesrst.tiiggaBattaiiroornn!E/DDnegetitaaniielleeerddiAAnngnaaClloyysmsipissaRnReyep,poorArtutg--uBBsotoiil1lee9rr91AAsshhV/AAccrryylliicc AAcciidd RReelleeaassee Areas, 3M Chemolite Center. Barr Engineering Company, August 1991. BCBaoarurrnr2t20y00,03O3.c. tCCoobotettrtaa2gg0ee03GG.rroovvee Niritarattee SSttuuddyy RReepporotr.t. PPrreeppaarreedd BBaarrr EEnnggiinneeeerriinngg ffoorr W Waasshhiinnggttoonn County, October 2003. CBBaoatltttueemllllbeeus220,000O00h..ioDD.eessMiigagnnyaa1nn,dd20SS0tt0rr.uuccttuurree ooff MMuulltt-i-CCiittyy SSttuuddyy.. BBaatttteellllee MMeemmoroiriaall IInnssttiittuuttee,, Columbus, Ohio. May 1, 2000. BpBeooruuflllaaunnoggreeorro,,ctBBa,.n,eVVsaaurrrggfoao,c,tJa.,Jn. tSSsccihhnnnGoorooerra,,tJ.LLJL.a.,kaaennsddwaHHtoeorrr.anbbuuEccnkkvlileer,,oKnK.m.CCe.n.ta22l0000S44c..ieDDneceteteeacctntiidoonTneoocffhnology 38: 4064-4070. perfluorooctane 4064-4070. surfactants in Great Lakes water. Environmental Science and Technology 38: BLBiuuettdeeennrh,hooP.fff,O,JlJ,s.,CeCno,ossitGa,.,,GGa..n,,dEETllchcooommmibboeer,,dCC,..,,P.FFaar2rrr0aa0rr2,,.DD,T.,oHxHiaacnnissteeynn,o,fKK.a.,,mIImwwoaaini,,iHuH.,m.,JJpuuennrgfg,l,uRRo.r.,,ooKKceetnnannneoedsdytye., iGGn..,, male cynomolgus Lieder, P., Olsen, male cynomolgus monkeys afte oral G., and Thomford, monkeys after oral Pdd.ooss2iin0ng0g2ff.oorrT66oxmmoiconitnthyths.so.f aTTmooxxmiiccooonllioouggmiiccapalel rSSfclcuiioeennroccoeessct66a99n::oa22t44e44-i-2n25577.. BLBuRut.teenn2hh0oo0f4fff.,, JJC..Lh.a..,raGGcatayeylrlooirzr,,atDDi-o.W Wno..,f, MMrioosokorrfeeo,r,Jg.AeLA.n,.e,OrOlasllsepenon,p,uGGl.a.W Wt.i.o,,nRReooxddprroiisccukkrsse,,J(.0,J. pMMearanfnlddueeollr,o,Jo.cHJ.Hi.,.a,anaonnadtdeZ.Zoobbeell, LRRe.eRggu.ul2laa0tt0oor4ryy. Toxicology and Pharmacology 39: 363-380. Characterization of risk for general population Toxicology and Pharmacology 39: 363-380. exposure to perfluorooctanoate. JDDaaankiukiainrny22200800,44.2. 0LL0e4etttteerr ttoo CChhaarrlleess MM.. AAuueerr,, UUS.S.. EEPPAA,, ffrroomm SSaattoosshhii DDooii,, DDaaiikkiinn AAmmereiriccaa,, IInncc.. January 28, 2004. DEDnM MviEErRRonm11e99n99t.9a.lLLReeetttsteecrarrt0cohDD,rr.L.iRRdi,icchhPePPtuuerrrddbyyo,r,o33uMgMh,aannOddntDDarrr.i.oJJ,ooyyCaccneeaCCdoaoo.oppeAerpr,r,ilBB,aattt1te9el9ll9lee... DD.. MMaacckkaayy Environmental Research, Ltd., Peterborough, Ontario, Canada. April, 1999. hwDDisaNNpRtRy/e22w00vr00e3s3w../dDwDriiavvsititssaiietooennmiouoffmuWWisata_teersrsseAAsppptprrioopoprriniaat/tiiooannpss pPPeerrrmmoiiptt DDraatiata.a. tFFioouuonnnddsoonnwlliianntee eaatt:ruhsle. Minnesota Departmentof Natural Resources, St. Paul, Minnesota http://www.dnr.state.mn.us/waters/watermgmt-section/appr~priati~ns/wateruse.htm~. Department of Natural Resources, St. Paul, Minnesota. Minnesota EREyRRsGG, M22P00C001A1.a.. CCJoaornrrureeassrppyoo3nn0dd,ee2nn0cc0ee1ffrroomm PPaauull BBooookk,, EEnnvviirroonnmmeennttaall RReessoouurrccee GGrroouupp,, LLLLCC,, ttoo MMaarrkk Rys, MPCA. January 30, 2001. EDEoRRuGGgla22s00,001M1bP..CACCo.orrrreJesusplpyoonn1dd7ee,nn2cc0ee01ffrroomm Paul Paul Book, Book, EEnnvviirroonnmmeennttaall RReessoouurrccee Group, Group, LLC, LLC, 0 to Dave Dave Douglas, MPCA. July 17, 2001. 3300 22000099..00003311 EEEnRRvGGir2o20n00m03e3.n.ta33lMMRCeCosotottutaarggceee GGGrrrooovvuepe,CChLheLemCmi.iccaaSllepSSteeewwmeebrreRRree9pp,ll2aa0cc0ee3mm.eenntt EEnnvviirroonnmmeennttaall OOvveerrssiigghhtt RReeppoorrtt. Environmental Resource Group, LLC. September 9, 2003. EEEnRRvGGir22o00n0m04e4.n.tFaFlaaccRiiellistgyo--uwwriciddeeeGFrFoluuuooprr,ooccLaaLrrCbb.oonnJIIannnvvueeassrttyiigg2aa7tt,iioo2nn00W W4.oorrkk PPllaann --33M1 CCootttaaggee GGrroovvee. Environmental Resource Group, LLC. January 27, 2004. EEEnPPvAAir22o00n00m22e..ntRRaelevvPiirssoeetddecDDtriraaoffnttAHHgaaezznaacrrydd,AAOsfsssfeeisscsseommfeenPntotololffuPtPeieroronfluoPruroerovoeocnctttaainornoiicacnAAdcciTioddxiaacnnsdd. iittNssoSSvaaletltsms..beUUrS.SS4.,. 2002 Environmental Protection Agency, Office of Pollution Prevention and Toxics. November 4, 2002. ExEEpPPoAAsu22r00e003f3..o PPPrreeerllfiilmmoiiunnraaorroyyctRRainissokkieAAsAsscseeissdssmamneednntttsooffStatlhhiees.DDeeUvv.eSel.looppEmmnevenintrtaoalnlmTTeonoxtxiaiccliittPyyroAAtsesscsotocicioianatteAedgdewwnicittyhh, Offic ofPollution Prevention Exposure to Perflourooctanoic Office of Pollution Prevention and Toxics. Acid and its and Toxics. April Salts. April 10, 2003 U.S. Environmental 10, 2003. Protection Agency, FTFrrraaannnksklplioinnr,,tJ1o.. f220P00r02f2.l. uSSocrcrroeeoeecnntiiannnggiAAcssAssceeissdss.mmeeJnnattmooefsftthFhereanPPkoolttieennn,ttiiSaaolllffvooarryLLRoonngge--RRsaanngg&eeeTAAaettcmmhronosospcplhhoegerhryii.cc March 2T4r,a2n0s0p2o.rt oAfcPceerfslusoeardotowcwtatn.oeicpaAcgiodv.ieJdaomckeest/F,raOnPkPlTin-,20S0o3lv-a0y01R2e-s0e1a3r3ch. & Technology. March 24, 2002. Accessed at www.epa.gov/edocket/, OPPT-2003-0012-0183. GGEinieevssiyyr,,o.nJP.mP.e.n, taaannldd SKKcaianennnnacanen,,anKK.d. 22T00e00c1.1h.noGGlloloogbybaal3l5dd:iiss1tt3rri3ib9buu-tt1iio3on4no2offppeerrfflluuocrrooooccttaannee ssuullffoonnaattee in in wwiillddliefe.. Environmental Science and Techno Iogy 35: 1339-1342. G"GTiheieessSyyc,,iLJeP.nP.t.,ifKKeaWnanoarnnl, KKdI.n?.,,a6ana2nd7d-Jn6oJ2on9ne,,ess,, PPD.D.. 2200001.1. GGlloobbaall bbiioommoonniittoorriinngg ooffppeerrfflloouurriinnaatteeddorogrgaanniiccss. The Scientific World 1: 627-629. pGGrioilldlliuillcaatnniddo,,nF.p.DlDa.n.taa.nnddJMMaaonnddeuelol,,fJ1Or..cS5.c.un11p99a99ta33i..onlMMaolorraMtleaidliittcyyinaaemm3oo5nn:gg ee9mm5p0pl-lo9oy5ye4esess of a ofa ppeerrfflluuoorrooooscttaannaoiiec acid acid production plant. Journal of Occupational Medicine 35: 950-954. HHchaaannrsasecentn,e,rKKizJ.aJ.t.,ioJJnooohhfnnssaoonnc,,eHH.l.0Oe.v,.e,lEsEldlodrfriiPddgFgeOe,,S1J..aS5n.,d, BBPuutFteeOnnhAhoofiffnf,,thJ1e.L.T.e,anannndedsDDsiecieckk,R,iLvLe..rAA... 22E00n00v22i..roQQnumuaeannnttitaittlaattiivvee SccihearnacceterainzdatiToenchonfotlraocgey l3e6v:el1s6o81f-P1F68O5S. and PFOA in the Tennessee River. Environmental Science and Technology 36:1681-1685. HpHeaarufuglguhohormooom,cB,ta. nBao.nainded SaScppiyyddde(evPvoFolOdlA, d)0O,,.. p e11r99f99l22.u.orTTohohceeiammneeeccshhlaapnnhiisosmrmiueunnaddceierdlry(linygPihtnhgeeFhhyayOpnpoodlSlciilppoeeAfmmiibicr)ceifefffaeecccdt. of of Biochimicae Biophysica Acta perfluorooctanoic acid (PFOA), Biochimica et Biophysica Acta 1128: 65-72. perfluorooctane 1128: 65-72. sulphonic acid (PFOSA) and clofibric acid. 2HH0oo0f3fff.,, PPP.TTe,r.,flVVuaaonnroddoeectVVaniijeevresur,,lfKKo,.n,iVcVaaanncdDDoionnnbggieenbn,,(WTW.r,i.,soEEpssimmearanunsss,,sEEc.LLi..), BBallnuudstt,,plRRai.a,ceannd(dPlDDeeearCCoonoeeencn,i,eWsWM.M.. ppf2ll0asa0tt3tee.ss.ssaPa))eErffnfrrvlouoimomrroottnhhomeecetwnwateneasestlteesTrrunonlfxossiccnchhioecellloaddgtctyiadananiddnndttbhhCieebhBBe(eTmellirggissiiraoannyptNNe22oro:urrstt6hh0lu8SSs.eec6aau:1:4s).ddiiassnttrdibbpuultatiiioocnen an biochemical (Plenronectes and biochemical effects. Environmental Toxicology and Chemistry 22:608-614. KeKAnpepnnlenideedydy,P, hGGa..rLLm..ac11o99l88o55.g.yDDe81er:rmm3aa4ll8tt-oo3xx5ii5cciittyyooff ammonium ammonium perfluorocctanoat. perfluorooctanoate. Toxicology Toxicology and and Applied Pharmacology 81: 348-355. a31 22000099..00003322 tKKoeexninncnieetddyyoy,f, GOa.L.m.L,m.,oHHnaailllul,,mGGpT.Te,r.f,BlrBuiortriteoelollcliti,aMnMo.a.RRt,e.., BBaFarronnoeedss,,CJ1h.eR.m.i,saatnnrddyCCahhneednn,T,oHHx..iCC.c.ol1o199g88y66.2.4:IInn1hha3al2laa5tt-ii1oo3nn29. toxicity of ammonium perfluorooctanoate. Food Chemistry and Toxicology 24:1325-1329. KKBieecnngneneled,dyyL,',BGG..,L..L,M.,urBBuputhteeynn,hhoof.ffRf,,>,.J.LLa.n.,,dOOFllassreernna,r,,GG.D.WW ..C.,., OO2'0'CC0o4o.nnnnoTorhr,e, JJt..CCo,x.,iSceSoaelcaoacgtayt,,oAAfM.p,Me,r.f,PlePureokrrikonionscs,t,aRnRoG.a.Gt..e., CBCririeittgiicceaal,ll LRR.eeBvv.i,ieeMwwsusriipnnhTTyo,oxxSii.ccRoo>llo,oggayynd334F4:a:3r3r55a11r.-,33D884.4G... 2004. The toxicology of perfluorooctanoate. KhKuuudmdoao,n, sNN..anaadnnddanKKiamaawwlasas.shhiiTmmhaae,,JYYo..un22a000l03o3.f. TTToooxxxiiicccoiilttyoygaainncddalttooSxxciiicceoonkkciiennseet2tii8c:csso4o9ff-pp5e7er.rfflluuoorrooooccttaannooiicc aacciidd iinn humans and animals. The Journal of Toxicological Sciences 28: 49-57. JLLLaau.u,., aCC.n,.d, TTShhtieibbvoeodndseeoaanuu,x,,L.JJA.RR.,., 2HH0aa0nn3s.soonnE,,xRpRo.GsG.u.,reRRooioggeeprresrs,f,Jl.uMJoM.r.,,ooGGcrrteeayyn,,eBBsEu.E.lf.,onSSatttaaennttdoounnr,,inM Mg.E.Ep.r.,eBBgunutatenennchyhoofiffnf,,rat `and mouse. I: postnatal evaluation. Toxicological Sciences 74: 382-392. J.L., and Stevenson, L.A. 2003. Exposure to perfluorooctane sulfonate during and mouse. II: postnatal evaluation. Toxicological Sciences 74: 382-392. pregnancy in rat MMAgPPeCCncAAy,1199S9t9.88.P.auSSlii.tteeMEEivnvanalelusuaoatttiiaoo.nn CCFehhbeerccukkarlliysits9&&,t 1SS9uu9mm3.mmararyy.. EErriicc PPoorrcchheerr,, MMiinnnneessoottaa PPoolllluuttiioonn CCoonnttrrooll Agency, St. Paul, Minnesota. February 9, 1998. M MMePPmCCoAAra22n00d004u4.m. 33fMrMomCCooDtatttvaaiggdee GDGroroouvvgeel((aCC0shheeBmmrooullciietee))BrSSoiittt.ee aaMnniddn33nM eMsoFFtllauuooPrrooolcclhhueteimmoiniccaCalolnDDtirissopploosasAlag.le.ncy. St. M Pauelm, oMriannndeusomtaf.romFeDbrauvairdyD5o, u2g00la4s. to Bruce Brett. Minnesota Pollution Control Agency, St. Paul, Minnesota. February 5, 2004. MMooooddyy,, CC..AA..,, HHeebbeerrtt,, GGN.N.., SSttrraauussss,, SSH.H.,., aanndd FFiieelldd,, J1.AA.. 22000033.. OOccccuurrrreennccee aanndd ppeerrssiisstteennccee ooff appreeerrafflluautoorWroaooorcctttsaamnnicetsshaullAffoionrnaaFttoeeraacnneddBoaotsthhee,errMppieecrrhffillogouuarnrii,nnaaUttSeeAdd.ssuurJrffoaauccrttnaaannlttossfiinnEggnrvrooiuruonnnddmwweaanttteearrlaatMtaoanffiiitrreoe-r-tirranaiginni5i:nngg 341.345. area at Wurtsmith 341-345. Air Force Base, Michigan, USA. Journal of Environmental Monitoring 5: MMoorriivwaakkii,, HH,.,TaTkaaktaat,a, YY.,.,aanndd (PFOS) and perfluoroocianoic AArraakkaawwaa,, RR.. acid (PFOA) 22i00n00v33.a. cCCuouonmnccecenlntertaranatetirioodnnussstooffcpopelelrrlelfcfutuoeodrrooioonJcsattapanraeenesssuulelffoohnnoaamtteees. (JJPooFuuOrrnnSaa)lloaonffdEEnpnvevirifrrloounnommreoenontctataallnMMooiocninatictooirdriinn(PggF55O:: A7755)33-i-n775v57a7.c. uum cleaner dust collected in Japanese homes. MMSuoorsvsssellyee,rr,u,Jn.pHJuH..bl22i00s00h3e3.d. mGGaeennnuesercraarlliiipzzteeddmasspttr.ruuccttuurreeoofftthhee JJoorrddaann SSaannddssttoonnee.. MMiinnnneessoottaa GGeeoollooggiiccaall Survey, unpublished manuscript map. `OOOEErgCCanDDiz22a00t0i02o2.n. fHHoraazzEaacrroddnAAomsissecsCssmooepenetrosoaftfPiPseoernrffmlaluunodoerrDooeoonvccettalatnnoepemSSeunultlff.oonnsaNttoeev((ePPmFFbOOeSSr))2aa1nn,dd20iit0tss2.SSaaltltss,. Organization for Economic Cooperation and Development. November 21, 2002. OAOlnlsseeennp,,idGGe..mW Wi.o.,,loGGgiiilllcliilliaannnvdde,,sFtFi..gDDa.t.,,iBoBunurolrlfeewrw,e,prMModM.Mu,c.t,iBBvueurrrhrioissr,,mkJo.MnMc,.s, MMiananmndedeenll,,wi1J..t5Sh..,aoacnncdudpMMataainondndeaelll,,eJJx.HHp.o.s1u199r99e88.t.o Appeenrrffellupuoiodrreocmooccittoaalnonoogiiiccc acid. Journalof Occupation Environmental Medicine 40: 614-622. investigation of reproductive hormones in men with occupational exposure acid. Journal of Occupation Environmental Medicine 40:614-622. to OPOlPlss.eennV,,eGGnk.WW at,e.,sLLwoaogrgalanun,,, PPP.-.,WW.S.,c,hHHuamanpnseserennt,,, KKJ...CJJ..., SSaiinmmdppsMsoaonnn,d,eCCl.A,.A.,1.1,B1.uBrur2r0ir0sis3,,a.JJ.MMA,,nBHoucurcrllueepwwa,,tiMMoMn.Ma,l.,eVVxopororasaruraarttehh,, P`aaAss.Psmse.ee,srssVismcmeaeennnnkttaInotoedfusfaswatparpierealrrulff,llHuuPyoc.gr,roioSoeoccnchtteauannmAcespsssueuolrcltffi,ooannJt.yyiClol.n,fflla6uun4ood:rrii6M dd5ee1a-ppn6rrd5ooe9ddl.u,ucJct.tHiioo.nn2ss0ii0tte3::abb. iiooAmmnoonoincticotoruripinnagtg.i.onJJaoloueruxnparloosnouffarttehhlee American Industrial Hygiene Association 64: 651-659. 3E2l 22000099..00003333 oOOfllwsseoennr,,keGG.r.W Ws.e.,,ruBBmuurprrreiirssf,l,Ju.MoJMr.o.,,ocBBtuuarrnlleeeswwa,,ifMMo.n.MMa.t.e,a(anPndFdOMMSa)aannndddeelpl,e,Jr.fHJlH..uo22r00c00o33cb.t.anEEoppaitiddeeem(miPiooFllOooAggi)icc aasssseessssmmeenntt `ocMcoefondwniccoceernniktntrreeaartt4isi5oeo:nrnuss2m6aa0nn-pdd2e7rmm0fel.edudioicrcaoalol csstuuarrnvveeesiiulllllafanoncnceeateeexxa(aPmmiFniOnataSit)ioonansns.d. pJJeooruufrlrunnaoalrlooooffcOOtcaccncuoupapateatti(iooPnnFOEEnAnvv)iirroonnmmeennttaall Medicine 45: 260-270. OdOollnsseoenr,nlG,iv.eWGr.Wa..,,nHHdaasnnessreuenm,nK,c.JK.J,o.,SStnetevvecennsseoonon,,nfLLp..teAA.r.,f,rlBBuuouarrrorroisstc,,tJJai.nMMes..ou, laafnnnoddnasMMtaeanndadeneldl,,ot1J..hH1e.r. 22p00e0r03f3clc.u.orHHocuuhmmeamainncals. dEEonnvnvioirrroolnnivmmeeernntatanaldl Science and Technology serum concentrations of Science and Technology 37: 388-891 perfluorooctanesulfonate 37: 888-891. and other perfluorochemicals. O1OlBls.se,ennH,,eGGr.r.WoWn.,,., RCChMhu,ur,rcchhM,,edTT.hR.Rd.,i.,zaMMdiiellhlelKrae,s,Jh.iPJ.,.P,, ZBB.u,urrrNriioss,,bJJi.MMl.e,.,,HHa.aBn,nsOsee'nnN,,eKKi.J.lJ.,., LLEuuMnnd,dbbeMerraggn,,deJJ.lKK.,.,,1AAH.rrmmiatitnaadggee,, ZJZA.omoBbeb.er,elilH,,ceLLarn.RrRo.R.ne,22d00R00.C3M3r4do...,ssMPPeaeedrrduffhlllutudooibzrrloaooodooccedtthaakdnnoacensssohuurilsl,ff.oZonr.,EaatNnteevoiaabrnniolddnetmootetit,hnheteJ.rarBlff.ll,uHuOeooarr'loNotccehhhieelPlmme,irEicsca.paMlelssc.it,iinMvettahshneed1ss1e1ee:lr,ruuJm1.mH89oo.,2ff-a1n9d01 American Red Cross adult blood donors. Environmental Health Perspectives 111:1892-1901. OJOMll.sse,en,nMaG,n.dW G.eW.l.,C,ChJuhHru,crchha,,ndTTR.ZR.o.,b,eLLla,arrsLsooRnn.,, EE20.B0B4,.., vvaaSnnerBBueelmllleec,,onGGic..e,nLLturuanntddibboenersrgg,o,fJJp.KKe.r.,,flHHuaaonrnsoseoencn,i,aKKnc.sJJ..u,lBBfouunrrarrtisse,, and oJo1.tt5Mhh9ee9.rr,-Mff1ll6uau1oon1rrdooecclh,heeJmm.Hiic.c,aalalssnidinnZaaonnbeeelll,ddeeLrr.llRyy.pp2oo0pp0uu4lla.attiiSooennruffmrroomcmoSSneceaaettnttltleera,,tWiWoansashsihoninfgpgteotornfn.l.uoCCrhoheoemcmotaosnsppehsheuerlrfeeon5544a::te and 1599-161 I. PPInaaoccreega11n999i91c1..Em33iMsMsiCCoonosmm.ppaaPnnaycye,CChhIenemcmoorlopiloitrteeatCCeeden.ntteeMrraSSyii,tte::19AA91i.irr DDiissppeerrssiioonn MMooddeelliinngg RReeppoorrtt -~ VVOOCC aanndd Inorganic Emissions. Pace, Incorporated. May, 1991. TTpaeanrnifiylyuaaossruuo,,oSSc.t.,,aKKneaansnnunlaafnno,,naKKt..e,, aHHnoodrriiri,,elYYat,.,edHHapanenararfrili,u,oNNri,.,naaatnneddd YYoraagmmaanasischhiictato,amNNp,.o. u220n00d03s3..inAAwasstuuerrrvv,eeyyfiooshff, birds, ard humans from Japan. Environmental Science and Technology 37: 2634-2639. perfluorooctane sulfonate and related perfluorinated organic compounds in water, humans from Japan. Environmental Science and Technology 37: 2634-2639. fish, birds, and `TBTuhhtiiebbnoohddoeefaafuu,xx,J,..JJ..RR,.S,tHHevaaennnsssooonnn,,,RRLG..G,A..,R,RoaogngdeeLrrassu,,,J.CM1.M..,2GG0r0ree3yy.,, BBE.x.EEp..o,,sBBuaraerrbtbeee,,peBBr..fDDl,.u,oRRrioicochchatarardndses,,sJuL.lHHf.o.,,nate dBd74uuu:rrtiie3nnn8ggh2-opp3frr9fee2,gg.Jnn.aLann.,ccyyStiiennvreraanttsoaannndd, Lmmo.Aouus.,ese.a.nIdI:: Lmmaaautt,eerCmna.all2aa0nn0dd3.pprrEeennxaapttoaasllueervveaaltlouuaapttieioornfnsls.u.orTTooooxxciticaconoleloogsgiuicclafaollnSSaccteiieenncceess 74: 382-392. VV20aa0nn3d.deeEVVxipijjovvseeurr,r, eKK.p.LIa.,t,tHHeorofnffsfo,,PfP-.pTTe,.r,fVVlauaonnroDDooocnntgagenenen,,suWW.l,f.,oEnEsasmtmeanainnssa,,qEuE.a.LLt.,i.,cBBilnluuvsestrt,,teRRb..r,,aatanensddDfDereomCCotoehenen,,weW Ws.t.MMe.r.n 2ss20ec04hh01ee3.ll.ddttEeexsspttuuoaasrruyyreaannpddattttheherensssooouutftphheeerrrnnfluNNooorrrottohhcSSteaeana..e Environmental Toxicology and Chemistry sulfonate in aquatic invertebrates from the Environmental Toxicology and Chemistry w2222e::s2t2e00r33n77-- 2041. W `GWreeossuttnVVdiwirraggtiienniriaaIDnDevepepts.tt.ioogafftEEinonnvviiSrrtooennemmreiennntgtaaTllePParrmoottReeeccpttoiirootnn. 2200A00u33g..usAAt,mmm2m0oo0n3niiuumm PPeerrfflluuoorrooooccttaannooaattee ((CC--88)) GW `DeWrceeoassutttonuonrdn,w22A0a0l0t0e44rP..lIannPPivhh.eaassstWeeige22asttW iWooonnorrkSSkpotplellueaatrnniinoffgnoosrrT,SSeIaaancmmm.p,plRlWiiennepggsotEErtnCn.vhveiAisrrutooegnnrumm,seetnP,nAt2t.aa0ll0OMM3ce.tedodibiaaerffoo2rr0PP04FF.OOAA aatt tthhee 33MM Decatur, AI Plant. Weston Solutions, Inc., West Chester, PA. October 2004. n 33 22000099..00003344 -- CERTIFICATION Cotes Corti rt res, This 3M - Cottage Grove Health Consultation was prepared by the Minnesota Department of a ComesteSoy pttem Health under .a cooperative agreement with the Agency for Toxic Substances and Disease Tea pe Registry (ATSDR). It is in accordance with approved methodology and procedures existing at the time the health consultation was begun. ees er Bioe-- sa Technical Projec CAT, $SAB, DHAC ATSDR eeku A Cm n ATS, rn es The Division of Health Assessment and Consultation, ATSDR, has reviewed this public health Dennen mo consultation and concurs with the findings. 2.2 Neva `Le TR T ebeRm obera ta ErlB weinrwen tment rE Arn Chief, Cooperative Agreement Team, SSAB, DHAC, ATSDR 22000099..00003355 L5S 3 5 3<3 & 85 1 Z 8 202%5888 A z 5 FY 23 |g 23 i 2 td LE EEeRnE cSlaEn oes 85% [R35] z PEER EEE 00000000 00000000 20200909..00003366 iti z ii E|i&pssaggiines ips| 2 sg & of H2cAlEi z gs ig HE Bo |a Err rss ==5 THE IEEE 00000 0000000000000 58 Ieee Fi 8 i iLH hi 3 g f iz: | 59y 20200909..00003377 oo  1233 31 a: 3 fiolres| ik 2 2 Hs 5, if 2s5i.e |iB no Ef Rg[|| 3ss HHi | \& l is Fedo connoo sll pRaRiTREE 20200099..00003388 wm DER La Paad OS RRO TRBikr rw a ELesnTo ps a RCE RE hE omanland i p Sask bST eOeE NSNEG ERA R EH Ia LIGEea S Pn R heea deAY i ON ERE TE Tr CE 3| esPeiEnECRRaEePsEx E%e SBudUbh,ReGaelEd G WLgT L et dl eaeET SaFacility wSNrL o RE lNNOTREE FitoTel sid :LEEPINNENTT A REIN a i ST Re, et mk tes Tog Ema oh ONTie Co T Ni defame ONG ed mre A, Se im fen Sea I ye 2. 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WY Nl 1 gE) Ce NA l3 w TONG stgen 1 fi 4 7 gs 4 yt { iH 2i885ti 20200099..00004422 oe g " hol 7 ofecatie 1 5 = Th ! 2; E iEn z x 31H3 i EE r H ALE 25 =i. 848 Bae, 8 SE 1 = a = iih YETI [iy 22000099..00004433 A a Ny NEA (ee Sd Sn Sa A RoAte 3 1 "| 2) Mi i Je NN A = A, Wi o1e MiWEE/ N HH | a ah "3 A Wr [0 sa [PRs RoeN i CA B ili A S URE T ST Foxy Cah Wl i 4 inNsCR | Mle Fee i in Lhe - fi | UC TRE pe 2 sMaNb I ihJis?h MLIEeR d Wy1 i fii fi 3 whi CsSeRNASEN} TER(BRTETeLTRfd 3 aes Zi) SE Cd eR OE Ba LCmNN E--x Vm Rie /AFFREIN ih ON Nps - Vinatyy~ SeN cohn:e \NaEIgESyE7R%FEri aGy C TETmSLE TE et See Sea en OSE SA etl FFiigguurree 66:: GGrroouunnddwwaatteerr FFllooww MMooddeell RReessuullttss 20200099..00004444 oo GEE her ETErSasEEdEae Lo TPiEr oy Beuphtnh TEst TREBEh LTne Gele, CegaE e e Bea iifeniabin: pEEESaE 8ow 2aEAE ean (opmmeaiaan7 pial x SosS HEE e L eny iy Ne Wr 4 yl La L rnn dS CEmaTl TR{AReERnON R ei CREATE DElEa C hl iTmTaS] OA NNGGE TaSuO h mpS a eed vg iT eAa nEN Osa Td A Tia) toN ALE wed RE I. o i] a as NRE ANEFr ol be See ETN fal Re s de3ad =: 5;. 3 swoha oadTSld e teaspneEE RC Np hT ep y te weno Slain AT R ON TN Ii id v2 FR LL Lf Sm ING ARE # 7 Ea Nit tra PWE m, eesrrJ)ET FFiigguurree 77: LLooccaattiioonn ooff WWaatteerr SSuuppppllyy WWeellllss NNeeaarr 33MM SSiittee LLEEGGEENNDD N PuPbulbilicc WVaCtaeterr SSuuppplyp'WvlVeelylll PPrriivvaattee WWeellll ((RReessiiddeenntitiaall oorr CCoommmemrecricaiall)) aMProductiWoeln 33MMMoMnointiotoridnnggWWelelll o 3M Production Well `@ NNSSPP(a(akkaa XXcceell EEnneergry)gWWyele)lll ~~~ BBoorrddeerr ooff 33MM PPrrooppeerrttyy 05 0 05 1 Miles 0.5 0 0.5 1 Miles a 20200099..00004455 oe Ta : INE FL S k o ONlY0 et | \ Seri - - ; he =\ F(r e Sp mBE8aREl5T aS6s | Fliemt SesE(HsEN" FIGURE 8: LOCATIONS OF KNOWN WASTE DISPOSAL AREAS AT THE 3M CHEMOLITE CENTER Source: Bar[ 199! san 20200099..00004466 FFiigguurree 99aa 33MM CCHHEEMMOOLLIITTEE BBLLDDGG 1155 11998866 AAnnnnuuaall AAvveerraaggee HF CCoonncceenntrtraattiioon ((uugg//mm33)) 3~..4400 UUrrbbaann MMooddee,, EElleevvaatteedd TTeerrrraaiinn 283 222.277 170 1.70 113 1.t3 os?0.57 in0 Facility SN &) 4 . { Y2 \ @ | 0.00 057 nv -0.57 Wy 3 -1,13 --11..7700 " 22 -2.27 we-2.83 3400540 --283 2.27 1.70 --113 -057 000 -5.40 ...............I I I I ,I ,,I I I 1 I t I -3,40 --2.83 -2.27 -t.~ -1.!3 -0.57 0.00 057 I I 0.57 113 I I. 1.13 170 1 .I ..... 1.70 11""==11KKmm I 227 283 ,,1...............1........ I 2.27 2.83 ,,I 340 3.40 SSoouurrccee:: PPaaccee 11999911 22000099..00004477 wm FFiigguurree 99bb 33MM CCHHEEMMOOLLIITTEE BBLLDDGG 1155 11998866 2nd HHiighheesstt 24--HHouurr AAvveerragee HHFF CCoonncceenntrtraattiioonn ((uugg//mm33)) 340 UUrrbbaann MMooddee,, EElleevvaatteedd TTeerrrraaiinn 283 - 25 2.27_ 170 1,70 Boundary Facility Boundary h ST , N >. wr Va \ i. i Y= NN 1.13 0.57 0.00 os? -0.57 -113 1 MA NZ hy -1.70 -227 -2.27 283 -2.83 11"" ==11 KKmm 340340 ~283 ~227 170 ~1.13 -057 000 087 113 170 227 283 340 -3. 0 I I.,,I I I I I. ! .... I I I I ! ..... I I I ! ,I I I I , -3,40 -2.83 -2.27 -1,70 -1.13 -0.57 0,00 0.57 1.13 1.70 2.27 2.83 5.40 SSoouurrccee:: aPaccee 11999911 22000099..00004488 oe LT 2/7 hii lh FOTN medSY | SolYoo a A ET SA i Ivo, Nfloomims" [Leedl [ES NonFe Cem iW iiie alafaont Re H VAT 4T We 4 ro SARNyNIL. o~l/ Ly7 SS A eS SY if RG Se h Nf) EESh TIh INEanTgT i2 Sm =xh A 9g. : ods Een J rr El ( m ieASAmTS BREN 4 | A Aa Aaw5E2 E JP AR ie? 4 a 12 ig 2208 422 5] i = | i a AT As 22000099..00004499 Ae BOGEN UNE (VE IME edg en N*N RhgOMSEN .ERECR E EAd R SLreTTT nA C EeTTEee en |[oa NC ON Approximate RlBoMof o1de9es8lee6dHeEeFxtent Ee Emissions SSAI INNT INER a Vm SlC t a ENarN hTe EBeER ak TL iy Lgl LOX $y mers] Ne BE I ee A FiZz shaftme eaeslel NboG) ee) 'i SRGRd -HS eeAe d w he l E Te nde UN JRE J Er we NY\ EATRIE a TN n ;: F~iigg.. 111t:: PPrriivvaattee WWeellll SSaammppllee LLooccaattiioonnss A =Private Well Sample, 2003 vom z~ = Private Well Sample, 2003 os 0 0,10,20.30.40,5 Mites 20200909..00005500 oe AAppppeennddiixx I1 DDeerriivvaattiioonn ooff MMDDHH HHeeaalltthh--BBaasseedd VVaalluueess aanndd SSooiill RReeffeerreennccee VVaalluueess ffoorr PPFFOOSS aanndd PPFFOOAA 22000099..00005511 MMeemmoo pr emma Date: Te Dougie Ween To: November 20, 2002 Douglas Wetzstein rr MIN Iq ESOTA i JY1] D)3| DEPARTMENT~ FEFrom: oe Phone: Suit: Subject: Dave Douglas -- Helen Goeden, Health Risk Assessment Unit (215057 (651) 215-0874 Reporte Rego for HethBed Valo nd Sf Referrals Response to Request for Health Based Values and interim Soil Reference Values Tismemequo stby their nsta Pi olsonCoe nt Agos QUE) This memorandum is in response to a request by the Minnesota Pollution Control Agency (08/21/02) Be foam for Health Based Values (HBVs) and interim Soil Reference Values (SRVs) for perfluorooctanoic APRON nd oan om acid (PFOA) and perfluorooctane sulfonate (PFOS). Thre med plished formation nthe of FOR 12 FOS. The MDH eid evil There is limited published information on the toxicity ofPFOA and PFOS. The MDH relied heavily on readily available toxicity summary information provided by 3M, EPA and the West Virginia Be ne Department of Environmental Protection. After reviewing this information the MDH modified the RREfDD aanndd RRIfCC vvaalluueesspprrooppoosseeddbbyy 33MM.. FEV Health Based Values (HBVs) =, " CChheemmicicaall CCAASS## EEnnddppooiinntt RRMfD (rng/kg/d) HHBBYV. PFOA 3825-26-1 Liver 0.001 7 PFOS 2795-39-3/ Liver 0.0002 1 1763-23-1 SoVt alea SaE) Soil Reference Values (SRVs) CChheemmiiccaall CCAASSH# EEnnddppooiinntt wor amszer ue PFOA OB ue PFOS 3825-26-1 2795-39-3/ Liver Liver Goonw RMRDfD ((mmggihkggd/d)) 0.001 0.0002 " fByOYSpm SE- RRIfCC ((mmgg/mm3)) 2E-5 2E-5 RReessiiddeennttiiaall IInndduussttrriiaall SSRRVV((mmge/kkg)) SSRRYV((mmegk/ke~)) 30 200 6 4O 1763-23-1 Tryon soe nt, Toxicity Value Sources: See Attachment II. rar et Cie eo Sas ate rs Tad Based on information currently available we feel that the above values will provide an adequate level of protection Lo A from exposure to PFOA and PFOS in drinking water and direct exposure to PFOA or PFOS in soil; however, there Eo ii is a degree of uncertainty associated with the HBVs and SRVs, and they should be considered provisional. The above criteria do not address impacts to groundwater as a result of soil leaching, food chain impacts or ecological impacts. py Please note that carcinogenicity studies in the rat have shown PFOA and PFOS to be potentially carcinogenic. However, tn mi bel cote Vv at this time the available data are not sufficient to determine relevance to humans or for development of cancer potency aevalues. mc Ht io 12 ic, 0, 075.5 Po MY S67 GE 15070 Environmental Health Division 121 E 7~ Place, P.O. Box 64975, St. Paul, MN, 55164-0975 (651) 215-0700 TE http://www.health.state.mn.us 22000099..00005522 pTeThrheseoddnauwtaaitwuhtiailiczrzeidnkinnitnthhgewe addieerirnviatvigoanotofiefothahenieseHHoBBftYV2ssfieiisrppsorrpoovvriindddaeeydd,niannAAdtattaraecclhhammteievnnetst o|I. .urSScuteanncdodanartrrddibaausstsiusomnupomtfio2pn0tsopiofefoan7r7s00cwekirilelooggnvrreaatmdn cll person with athdersienkvainlugesw.ater ingestion rate of2 liters per day, and a relative source contribution of 20 percent were used to calculate these values. MDH is nthe processof evsing is Healh Risk LintFogroundwater oe, The MDH is ky to recommeinsdt MDH is in the process of revising its Health Risk Limits for groundwater rule. The MDH is likely to recommend that the standard assumptions of70 kilograms and2 lcsdaybereplaced by 3 body weight and an rake rae more the standard assumptions of 70 kilograms and 2 liters/day be replaced by a body weight and an intake rate more proprfeor cle. 104s commendation fs cepted nd prod se, HEN wold ily dcr appropriate for children. Ifthis recommendation is accepted and promulgated as rule, HBVs would likely decrease by coro a factor of 3 to 4. "iTTshhkee ddvaoatltauauetstillizpzreeeddseninntttehhdee ddineirhivveaatiMotFnCooAfnt'thhfsee SRDrRVaVfsts iGisuppirrdoolvviiinddeeedsd infnoAArtttttahaecchShmmetenntu1tI.Ir.TThnhee dHdeeefaaftuhtlt eePxxapptohoswsuuaryree,ssTceeecmnhairniioscslaanSrdupteaprogtrett `Document (Working Dra, Janury1999)were ublizedtocalculate these values. risk values presented in the MPCA's Draft Guidelines for the Soil-Human Health Document (Working Draft, January 1999) were utilizedto calculate these values. Pathway, Technical Support "wTThhheeerMMeDDdHeHg'r'ssadaaauutttihhooonrriihttayysttohoepparrodomymuaolclgcagutarerehhdee.aaltthhSiraiskik lllim,iisttshuuennHddeDerr'ttshheeanGGdrrooSuuRnndYdwSwaatptererorvrPiredoectdetcritsioonntAAcccttiss llii1mmiiStteeedrdvt0eo5ss8iutuftaitioeonnss wavaddehvvleiirccoeeepdeiisesdsgsuurfeaeodddraftftohoiorernspsppuheeraicpsfiofiasilcceresosafiedtespysrwoowhvcihecdeurirrnergeaadcn.cooSnonipttmaeamirmlaiinrllaniynn,atithfhheoaasrsHdbbeBegeVernnasdaddaetentitdeoecnctS.teeRdd.V. s A soc, provided As such, neither he HBVno are intended to serve neither the HBVs nor SRV sre as interim SRVs are developed for the purpose of providing an upper limit for degradation. ce cc: ALLnaanrmreyy KGGuuuskstot,,wMMskDD,HHMDH `JAJGiiemnmnnyKKeeeKlSllmluyyik,,tehMMw,ODsMkHHDi,HM. DH GSSLhuheeekrlrlellyCeehyySamBBrpuiuetmrhnm,atMianne,Dr, ,MMHMPPPCCCAAA NLaiLMuruarkyreyaDSCDyohymlameormpnoe,ndnd,tM,ieMMCr,PPAMCCPAACA JLMNiaoiuccnrhhaaiBeS!luoSSleeaamnnntt,ooorMroo,P,3C3MMMA John Butenhoff, 3M Eavironmersal Heath Division + 121 . 7% Pace, P.O. Box 64975, St. Fal, MN, S164(6501)259.07700 Environmental Health Division 121 E. 7~ Place, P.O. Box 64975, St. Paul, MN, 55164-0975 (651) 215-0700 pine hal suc ms http://www.health.state.mn, us 22000099..00005533 AATTTTAACCHHMMEENNTT I[ "DATA FOR DERIVATION OF GROUND WATER HEALTHBASEDVALUE (BY) DATA FOR DERIVATION OF GROUND WA'I'ER HEALTH BASED VALUE (HBV) Compound cask: Compound NNoammee:: CAS #: LLUnOOcAeArEEtLaLin((tiinynggFeeassctttiiooron.n):: Uncertainty Factor: MNReOodDdi"iyfiyninggFaFcaicotorr:: RID*: Heh effec: Health effect: P3Pe8err2ff5llu-uoo2rr6oa1aocc(ttOaacnntoo.aa1tte6e,((2PP0FF0O2OAApe))rsonal ccrmmunicawittih on Dr.John Bteshoff, 3) 3825-26-1 (Oct. 16, 2002 personal communication with Dr. John Butenhoff, 3M) 3330mm0e0gk/(k3ggi-/dnaatyyrspecis; 10- trspecies; 10subhvoniqo-chonics 10 3000 1 LOAEL10-NOAEL) (3- interspecies; 10- intraspecies; LOAEL-to-NOAEL) 10 subchronic-to-chronic; 10 01.001 mgpitay 0.001 mg/kg/day Liver Liver RelativeSourceContribution (RSC): 20% Relative Source Contribution (RSC): 20% OOApnrpaslliSSelodoppReeisFFkaaccLtteoovrer:l:: NNNAAa Applied Risk Level: NA HBY HBV =(m (RRtIIaDDk.,eE mRga/kte~K /(d2) (RRpSeE SrCC))da(1y1A 0000000u~1) ktgs)/mmg)) Intake Rate (2 L per day/70 kg) - 000 mgk0p02092Li)ke1d000ugg) = Tug = (0.001 mg/kg/d) (0.2) (1000 p,g/mg) = 7 !ug/L 0.029 L/kgjd Data Data 1."SSoouurErccePess:A: Revised Draft Hazard AssessmentofPerfluorooctancic Acid and lsSalts(Nov 4, 2002); 2321.... EE3EPPPMAAALiRDDfrereaavtffiittsmeHHedaaDzDzraairrranddfktiAAHnssgsasWeezassatssrdmemerAenHnstetsoaeoflsfstPPmheererAffndlutuvcooirrfsoooPoorcecytrtfaalfnnuoorooiriPecoeoAfAclcctuiaioddnroaaoinncoddcAtIIactssnideSSaaaslnluttldssfo((IFtnFsaeetbSbea22l(0t0A0s0p2(r2)Ni)l;ov2040,2)2;002); 4435.... S333uM MMbeLSSrooioifilenltiSSimcccrreTeeoeeDxnniriicinnniggtkyiGGnuSguitiduW dedelialeiitsnneeerossnHffPeooearrrltPPfhlFFuAOOoSdSrvo((icMsVtoaaarnyyyef22so0u0r0l02P2o)c)n;;raftlueoProotoacstsainuemsuSallfotinnatCey(nAopmriol l2g00s2M);onkeys. 5. 6. 3`SSSeuMeabaeccSaaohttirloettnSaiaccl.r.T,eTeToonxoxiixcnccigiitooyGlluoSoiggtdiuieccdlaaiilelnsSSeocscinifeePonnreccreePfsslFu66Oo88rA::o22o(44cM09t-a-a22rn66ce44hs,,u2l220f000o200n)22a.;;teaannPddotassium Salt in Cynomolgus Monkeys. 6. 3M Soil Screening Guidelines for PFOA (March 2002). *n+oCCtaarSruccfiifnnioocgigeeennniticcfiittoyyassttquuudaidenistiiantttihhveeerraatsthshaeavsvseemsesnhhtoo.wwnnRPePpFFrOOoAAdtutocoibbveeeccraainrcdniondgoevgeeenlnioi.cp.meHHnotowawelevveeercr,t, ast,thhibissastiemdecttnhhestsauvdaaiielsalbilanedrdbtaastlaasaenrrdee rWabIbiFs,IoFccu|rdaatye)veislshuingchleersthoawndhoasedsegcraeusitnhge verasetosxaicnitdyn . Heowwet drueeexops roavsped.eOmviranraiat,nioun linfa yepemarpsals(ilsaehreuams not sufficient for a quantitative assessment. Reproductive and developmental effects, based on studies in rats and rabbits, occur at levels higher than doses causing liver toxicity. However, due to rapid elimination in female rats (serum half-life of 1 day) it is unclear to what degree the fetuses and neonates were exposed. Ovarian tubular hyperplasia has aSlincebeeffnecotbssweervreedoibnsfrveemdalatrthseatldoowseessadoselovwal3at1e6d)mgW/odme(nrodtoe naoNOaApEpLeawrashaovte dtheetesrmmienesd cfoihsicsrefefeecnt also been observed in female rats at doses as low as 1.6 mg/kg/d (note: a NOAEL was not determined for this effect smienccheaenfifescmtshwtereexiostbsseirnvtehde female rit at the lowest dose evaluated). Women do not appear to have the same active secretory mechanism that exists in the female rat. Evironment Tesh Divison 121. 7% lc, P.O. Bo 64975, S Paul, MN, SS1610975 (651) 2150700 Environmental Health Division 121 E. 7~ Place, P.O. Box 64975, St. Paul, MN, 55164-0975 (651) 215-0700 ip wn esi se ns 3 http://www.health.state.mn.us 3 22000099..00005544 cCCaoomsmppoouunn dd Name: Name: CAS 9: P2Pe7er9rff5ul.uo3or0ro.oo3occpataonnteeassusulslffioountmaetse(a(PlP)FFOOSS)) (21107775966.5331--6322,393--211300((fpf2rroepeteeearssssasalioluttay)mlcosmaml0rication with Dr. ohn utenboff, 3) (Oct. 16, 2002 personal communication with Dr. 2ohn Butenhoff, 3M) LOAEL (ngesion): 0.15 mepgday LOAEL (ingestion): Uncen Factor: 10000 merspcie: 10+ inspec: 10subchronic hrc 3 LOAEL-o- Uncertainty Factor: Moding Facor: N1 OAEL) Modifying Factor: RID 0.0002 mpeiany RfD*: 0.15 mg/kg/day 1000 (3 - interspecies; l 0 - intraspecies; 10 subchronic-to-chronic; 3 LOAEL-toNOAEL) 1 0.0002 mg/kg/day Healthc: Liver Health effect: Liver Relative Source Contision (RSC: 20% Relative Source Contribution (RSC): 20% Oni Sipe Factor: NA Oral Slope Factor: NA Amid Rik ed NA Applied Risk Level: NA HBV HBV :=((RRnfDfi).,kmmeggR/kktgee/d)()2(RRLSSpCCer)) 1d(10y0007000~kstg)i/mmsg)) Intake Rate (2 L per day/70 kg) " -(00002ma[idv)02e101000wimg) = 1 gh = (0.0002 mg/kg/d) (0.2) (1000 btg/mg) = 1 lng/L 0.029 L/kg/d Dua Data 1SS)oouurErccPeeAss::Hazard Assesment sd BiomonirinDatson Prfuorocetan Sufontc FFOS (lly 2000) 5221)))) 43)) E333S30uVMMP1b1ALcSLShoiHoiritfiolaeeliztSiSicacmmcrrdreeeTeDeAeDronnsiriiisninnneekggksiysiGnGnSmguguieuidWtdnelteialasritnnneederossnHHBffeoieoPoraaremtlrtPPhholFFnoAAOOirdtSdSoov(vrin(iiscnMsMootgrayrayyyDnas2ff2oot0l0arr0f02PPoo2)nne).;rrsPftloeueroftPlruoaooorscontseancsteanssSueulllfSoftunolafnoteeCnya((AtAnepopr-rmiilolPl22F0g0O00sS22M):(;2oun]kye2y0s00S);cat 4) 5) alaS3.lVu.t,TboTcCxhoocrxmoicmonileoicolnogTtgisoiecxaoailclniSSteyccsiiSeeptnnueccdceeisseis66e6o8s2n:21UP45e9.nr-2f2lc66u44oe,,ro22no00c00ti2an2;nReaaisnnudkdlfoAnsatse ePortatssiouxmPSRaOlSt.in Cynomolgus Monkeys. Seacat et 5) 3M Comments on lnterspeeies Uncertainty in Risk Assessment for PFOS. o**CoCaaurreiinlnocggeeeniicciftoyyr ss3tuuqdduieassninsntithhveeeroatst ehaavmveeessnhho.owwnnRPPepFFrOOoSSdut1cotbibeveecs2arrnccdiinodogegevenencli.co.pHHmoeownwetevvelerrs,, tastt,thhibissstmimeeeattnhheesl aveasilab3b ledodoastaa2as9rrdee Tabb, occur not sufficient rabbits, occur at levels ighr than ose casing Tver icy. for a quantitative assessment. Reproducti~'e and at levels higher than doses causing liver toxicity. developmental effects, based on studies in rats and DPDartaetepea((rPPerrdeebppyaa:rreedd ooGrroM osddoeidniefi)ed:): November November 14,2002 14, 2002 Prepared by: H. Goeden avponas stshkhDiaviesinon s 21. 7lcs, 7.0, iBox 649755. Paul MI, 51640975 651) 215.0700 Environmental Health Division * 121 E. 7~ Place, P.O. Box 64975, St. Paul, MN, 55164-0975 (651) 215-0700 http://www.health.state.mn.us 4 22000099..00005555 cCCaoosmmpwpoouunndd NNaammee:: CAS #: AATTTTAACCHHM MEENNTT IITI 'DATAFOR DATA FOR DERIVATION DERIVATION OFSOIL OF SOIL RREEFFEERREENNCCEE VVAALLUUEE((SSRRYV)) 3PPee8rr2lfl5uuo2or6roo1aocct(tOaacnnt.oosat1te6e,((2PP0FF0O2OAAp)e) rson communication withDr. Jo Beshoff, 0) 3825-26-1 (Oct. 16, 2002 personal communication with Dr. John Butenhoff, 3M) LCLcOOeAArEEaLLi(o(iiynnggFeeassctttiiooron:n):: Uncertainty Factor: MMROeDoddiifyyiinngg FFoaccitoorr:: RiRcfDh*,: RfC**: 33300mme0gr/(kk3pg.i/ddmaaeyyrspcis 10 trpecies; 10sobhioni-o-chronis 10 3000 1 LOAEL10-NOAEL) (3- interspecies; 10- intraspecies; LOAEL-to-NOAEL) 10 subchronic-to-chronic; 10 00E1..00S0011mgm mengk/'kggi/tdnayy 2E-5 mg/m~ DDeerrmmaall AAbbssoorrppttiioonn:: 10% 10% (MPCA (MPCA DDeeffaauulltt ffoorr oorrggaanniicc ccoommppoouunnddss)) HHHaeezsaaklrthhd feQfuffoetc:it:ent: Hazard Quotient: 0LLi2ivve(errMPCA targetrisk value) 0.2 (MPCA target risk value) IOOnnrbalallSSallioooppneeUFFnaactcttoorRr:i:k: NNNAAA Inhalation Unit Risk: NA RRIenesdsiuiddseetnntrtiiiaalSlRSSVRR:VV:: 332000mm0egh/mk.gg Industrial SRV: 200 mg/kg DDaaata1SS)"oouurErccPeessA:: Revised Draft Hazard AssessmentofPerfucrooctanoie Acid and Is Sats (Nov 4, 2002); 2321)))) EEE3PPPMAAALDiRDfreraeavftftiitsmeHHedaaDzDzraairrranddtktAiAHnssgssaeezWssaassrtmdmeeeArnntsHtsoeoeafsflPstPmehererfAfnlltuucoodrrfooPoocevctrftfaalonnuicrooiPirecoesorAAlccctuiaoioddnroaoairnnocdcdAtIIyactssniSdeSalaastlnutsldsf((oIFFtnseaebtbSea22l(00tAs00p2(2e)N);l;ov2040,22)002); 4534)))) 333SuM MMbeLSShooirifiolelntSSiimcccrTreeeoeexDnniriicinnniggtkyiGGnSutguiuidW ddeielaeliitsnneeerossfHnfoeoPraerlfPtPhlFFuAOOorSdSovo((icM sMtoaaarnyyyefs22ou00rl002fP2)oe).r;rafltueoProooacstsainuemsuSalflotniantCey(nAopmroill2g0u0s2M);onkeys. 5) 6) SS3SeeuMaabcccSaahtotrlotetnaSiaclclr,.T,eeTTonoxoxiixcnccigiitooyGlluoSoiggtdiuiecdclaaiilelnsSSeocscniifeePonnreccreePfsslFu66Oo88Ar3:o24o(49cM9.ta-a22rn66ce44hs,,u2l220f00o0002n22)a;.;teaanPnddotassium Salt in Cynomolgus Monkeys. 6) 3M Soil Screening Guidelines for PFOA (March 2002). a*+rCCaaorrctciinnsoouggelennciiceciinttyyfossttuuddiqieeussniintntathhieevrreatt ahhsaasvveesssshmheoonwwt.nn PPRFFeOOpAArottdobubecetcciaaarvrnccediinndoogegevenenilcioc.p. mHHeonowtwaelevveeerfr,f,ecaattsht,hibissasttieimdmeeontthhtee aadvvaaiiillaaibbnlleertddesattaa are not sufficient for a quantitative assessment. Reproductive and developmental effects, based on studies in rats aatnsdrrabubims, BoccIurEatfev1edsahyi)gihter uhanndoscteosWclhauaseidneggarIeverrhetoxficeittuys.esaHroweeveor,ndsuewearpedxpolsiedo.aiOvoanriiannfuenlalaer and rabbits, occur at levels higher than doses causing liver toxicity. However, due to rapid elimination in female roehayyttppsreem(rrsippealnraucesmiidnahfhhaaoaslsft-lahliilsfsseoeobfbeffeeeecInntdosoaoibynss)ceeeirvtvfieesddfuniisnnclffeweeamemraaetloleeowbrrahstteasrtsavtdtededdgoaortseseeetsahthaeeseollfoeowtwuawsaeesso11sae..n6e6dmemvngasgelh/oukanegtat/edtde)s((.nrwooeteeW:r:eoaNmeNxOepOnAoAsdEeEodLnL. oOwtwvaaasaprnniaopotntatturobuhlaavre hdeetesrmamieneadctfoirvtsheiscreeftfoercyt mechani hat exi1tthse femalert. since effects were observed at the lowest dose evaluated). Women do not appear to have the same active secretory mechanism that exists in the female rat. o*+*4tTTchoenrsehiiisdieinnrrssueufdfffiiteccobiieeeannttvoiilnaftonirlmefacthioeomniorconantlmhthaeenatdtootxtxhiieccriooelfloooogrgieiccntaahlleeefnfffbeeacctltsstioofoPfnPFFeOOxpAAosffuoorllelloopwwiainngtg iiannhhaiallaaattniitooinncieepxxapptaoesdsourfree..bePPaFFOmOiAAnoiirss: PCnpaaaotttrhhccwwoiaannyy.so,igdee33rnMMedinhhtaaoassnbissemuuaggalgavsesosbiltuaeettddiwleasitRRchhfCeCumnookficfn2a2olE6wa--nn55drmmethlgee/ymvrea3nfocbberaaessoteehddheuooimnnnahganaesgla.netnicoTeinrhicecexceCpxxAoppsToousTorurerrsepepaggotuurhitiwddegeallyeiinnnieesefrafonrsrcteichcadhiepemRamtIieiCcdcaaotllofs be a minor f1o1u.nd3(0 be found to be carcinogenic in animals but with unknown relevance to humans. The CATT report mniginIntShoisbRiecfenrceenocfe iVnaflouremation the provisionl RC sugasted by 3M willbe mg/m3. In the absence ofinformation the provisional RfC suggested by 3M will be ulizd or generated a utilized for the evelopmenotf RfC of 1.1E-3 the development of an interim Soil Reference Value. 5 22000099..00005566 cCCaoosmmHpp:oouunndd Name: Name: CAS #: LCLhOOcAAeEErLaLi((oiinynggFee~sctt'tioioornn:)):: Uncertainty Factor: RMOoDding Foor. Modifying Factor: RID*: Rice RfC**: Dermal Abserpion: Dermal Absorption: HHeeaatlthh eeffffeecct:t: Hazard Quotint: Hazard Quotient: OIOnnrbalalSlSialioooppneeUFFnaaicctttoorRri::sk: Inhalation Unit Risk: P2P7ee9rrf5ol-ur3oo9ro-oc3otca(tnpaonctessauusllsffioounamattesea(l(PtF)FOOSS)) 2(11O777ct966.533--.12326393,--.2130 0(((pff2rroepeteeearsssssaoainlluta))lmc salt) ommun ic ati on it h Dr.John Bs en bo ff , 3) (Oct. 16, 2002 personal communication with Dr. John Butenhoff, 3IVl) 1000.11055 0mme3gp/kknagei/rdtsanpyyeies: 10 inraspesies:10subchronic t-chronic; 3 LOAEL10-NOAEL) 0111 .0000002(3m-einktgeirsapnecyies; 10 - intraspecies; 10 subchronic-to-chronic; 3 LOAEL-to-NOAEL) 0.0002 mg/kg/day 2S2E-5 mmyg/nm'~ 10% (MPCA Defaultfororganic compounds) 10% (MPCA Default for organic compounds) Liver Liver 0.2(MCA tarisgkvaelute) 0.2 (MPCA target risk value) NNNAAA NA RRIneedssuiisddteernintatiliaalSlRSSVRR:VV:: 406memmlege/ek..g Industrial SRV: 40 mg/kg DDuaatasSSotouaurrcSceeossu::rs: D211)))ataE3ESPPMoAAuLHriHacfezaesazt:airmrdde AADsrssisenesksssimmnegennWttataaenndrd HBBeiiaoolmmtohornAiidttovoririsnnoggryDDaaftotaar oPonnerPPfeelfrcfllruuoocsrrcooaoonccetasanunleefSSounulalfftonena(attAeepe---lPFF2O0OS0S2()(Jluyly 22000000)),; 2543)))) 33S3MMM uSLSooiifiblelStSicmcrcrTeeeeoeDnhxniriiinnncrggkGiGnSuoguudideWdilneiealitnsneceerossHnffoeoPrarelrtPPhlFFuAOOoSrdSov(o(iMscMotaarnyyyesf22ao00lr00fP22o)e,n;rsftlueoProooscstaunemsuSlaftoniantCey(nAopmroill2g0u0s2)M;onkeys. Seacatet 4) 5) 3aaSl0lu.,1,bTTcChooorxxmolcmnioeoicolnogTtgiosiccxoaaiclliStSIyecnetiSeentnrucscdepeiessecsi66e8o8s:n:22UP44n9e9c.r-ef22rl66ut4a4o,i,rno22to00yc00ti32an;;nReanisndudklfoAnsasteesPmoetnatssifuoxmPSOaSlt.in Cynomolgus Monkeys. Seacat et 5) 3M Comments on Interspecies Uncertainty in Risk Assessment for PFOS. "n*oCCtaarsrcucifinnfoicgcgieeennniticciiottryyassttuuqdduiiaeensstinantttihhveeeroaattsshheaasvvseemessnhhtoo.wwnnRPPeFFpOOrSSodttouobbceeeccaaanrrccdiinndooeggveeennilicco._pmeHHneotwavleevereff,re,catstt,thhbiisassitiemmdeeottnhheesstaauvdlaiaielbsablilenerddtasatansaerdee bis, accu not sufficient afot rleaveqlusahnitgithaetrivtehaanssdeosssemsecnat.usiRnegprvoedrucotivxe yand developmental effects, based an studies in rats and rabbits, occur at levels higher than doses causing liver toxicity. C*o+n*TsThihederersereids 1iin0nbssuuefffafiivccoiileeanntttinilneffcoohrremmmtaiitciooannl aoonntnhedtthhoeexrtioecxforicleoolghoeigcicaahllaeefflffeeoccnttsseoxofpfFoPsOFuOrSeSaffooallllooywwiinnIggs aiinnhhpaallaaattiioonn ee1 sxppbooessaaurreme.i.nPPorFFpOOSShiiyss nn.oott `gc35eoMMnnesssiruudgigegrgceeeesdsxttpteeooddsbaauerRRaeIfvCCgouSsloiadotfeifll2e2i5nEc.eh-f44eomcnahnidcedaml22ia6Ecn--da55ltmmhsegyfr/eomnfuo3nrffdeoortrhPPebFFeinOOchaSSaralcaanintdoidognPPeFFneOiOxcApA,oi,snurareerisesprppeeacactlttihisvvwBeelaltyyy..isTTahhneetUicvvTiaapKllauOeteeWdffootrroPPvbFFeaOOanAAmcweiwnaoassrobpbhaaaustshmeewaddnaoosynn.. BaPInFFghOOenSeSearapsippchpeieeaxnarperosetsotouofbrbeeiegcncuaafirrdocceimlininonaegotegfinoetoirnhccneinhnperrmaaotvisciasbsilusotnfiaotluisnRnodIoktCotccbflloeerascrPawwrFhchOienetAtohhge(eerr2nsS-iuOc5ggiEgnmeeaSpsnite'icmd)amclsseuhcbghugatienwsitsintemhdouiobfnfyakasnc3otoMimwonnwniilrlselrleeblveeeavunaicnaletittz0ooehndhhuuufmmmoatraantnnhssse.. dInevtehleoapbmseenntcoefoafnintfoermriatioSnilthReefperorevniscieonVaal lRufCfofroPrEPOFSOAss (w2elEl-.5 mg/m3) suggested by 3M will be utilized for the development of an interim Soil Reference Value for PFOS as well. DaPDtraeetpea((rPPerrdeepbpyaa:rree1dd.ooGrroMMsododeidfnifiieedd:): Noverber November 14,2002 14, 2002 Prepared by: H. Goeden 6 22000099..00005577 AAppppeennddiixx 22 PPuubblliicc CCoommmmenenttss RReecceeiivveedd 22000099..00005588 oy {3 UNITED UNITED STATES STATES EEWNNAVVSIIHRRIOONNGNMTMOEENNNTT0.AAC.LL 2PP0RR4OO6T0TEECCTTIIOONN AGENCY AGENCY WASHINGTON D.C., 20460 OFFICE OF PREVENTION, PETICIDE,<:3 AND TOXIC SUBSTANCES SSeepptteemmbbeerr 11,.22000044 VVIIAA EE-MMAAIILL MMErn.rv.iJJraaommnmeeessnKKteaelllllyyHealth Division ikEMMainminevneninserleossnoolmttaaeynDDteae@plpaaHhrrttemmeaelsetnthantatoDtolfeifmvtHHisueeiaohalsnltthh james.kelly@health.state.mn.us DDeeaarr MMrr.. KKeellllyy:: ConsultaTTthhiaaonnnfkkoyryootuuheffoo3rrtMthheeCoootpptppaoogrrettuuGnnriiottyyvettooFappcrrioolvivtiiydd.eeTcchooemmmAmegenentntsscyoonnhtthheaeaddnrruaamftstbPPeuurbobllfiiccgHHeeneaearllattlhh comments, and also some specific points. General comments re Consultation for the 3M Cottage Grove Facility. The and also some specific points. General comments are addressed firs Agency has a number addressed first. of general comments, GGeenneerraall CCoommmmeennttss commentEEsPP.AAFihhrsaatss,nnEooPtt Arreevuviniedewewreesddtatthhneedsddtoocchuumnmeeeenndtt ffooorrr tttoooxxxiiicccooolllooogggiiiccaaalll vaaacclccuuuerrsaaccfyyo,,qbubauunttthhiatasastssieevvveeleryraaallsoosvevesersraallll cpHpooootmwteeenmntvtieeiaanrll,tshh.eueasFaleliottrhhsft,irtiEhsskPeksAotoefurfpnmpesderer"ffrlRlsuutIaooDnrr"oodoosacctntthdaaenn"oonRiieccIeCdaa"ccfiiotddrh((trPoPFoxFOiuOcgAoAlh))oogaauninhcedtdalppdeevorracfflulluumueooesrrnototooosccqttauaatannzneectihsstueauldtlfiovfinenalatAyteepap((sePPsneFFsdOOsSiS)x.).| HitimhmoapptwlliEieeevPsseAttrhh, arautetsqtteuhhieeorssfeeesthaaperrreeitoeEErrPPm0AAs--dh"deReeriIriDivve"eelddaanvvdaasll"uuoReenssf,,Ctaah"nnetddhInrhhotaaeuvvggeerhabboteeeueedtnntRhissesuukbbdjjoIeecnccuftteeomddremttnaoottsttihhoaeenttvvaSiciygghsooetrrdeoomuuinss(IAppReIepSepe)re.rrneedTvvihixieeew1w tvEvhaaPallutAueeEtssPhppAerrreecrsfseeoeqrnnuettieerrddeesqbbuypyersttihotheser ttMMohiainttnhnnMeeeisDrsoorHtetaalecDDaalseelepptaoahrnrettsmtehmeeevnnaItlnooutfeefHgsHersaaeoltaemltdtehhtRh((iMisMnkDDgIHHont)f)hoeaarrrrmeetanhntoaoiotntnEERPSiPADyA-ssc-tcaeoalmrlccRu(ulIIlRaaCttI,eeSddo).vvTaaalhtluueaeess. EmmthiPiennAIiimRtmIhuuSemmrpermfmooacarekekseesr,eccqlleueaearstttshhaathttattthheMesseDppHrroocppaoallsseethddevvsaeallvuuaeeslsuwweeserrseeomnnooettthddieenrrgiivvoeetddhebbryythEEaPPnAARnnIoDorrs produced or RfCs, produced though or at a through the IRIS process. assessmSSeenectcooonnndd,,PMMFDODAHH(cc2ii0tte0ess3)EEaPPsAAsoddurrraacfftesddoofccoruummteheenintrtssan((a22l00y00se00s--.2200M0022D))HaannsdhdaoaupplrrdeeblleiimmaiinnwaaarrryyeEEtPPhAaA trrhiiseskrke have tbabhseeeseerennessrrhmaaappveiineddtbaaoeddnevvnaaPnnFrcceOeecssAeniitn(n2att0nhh0aeel3ppy)hshaaeasrsrommsfaoacucotrokhcekienismnefoetotidirccetsoshfaaenniarddacttnooatxxliyoicicsfooeotllsoh.ongegMyy DlooiffvHePPrsFFthOoOoxAAuicldiaatnnbyddeaInPa:dF'wFOOatSruS.em. toIIhnrnaatafdditdhndideititriienoognnhs,,aivne thrrhooaeddvereeenntithssma,,pvlaaeinncddbaetttehihnoeenrsppefoocossesrsniitbbthllaeeenrraqeeulyllaensevtevaisatnnoacctfeeiotvhofeeftathmhniaiossldymmesoioosddfeceaooconftfdiaouacncctttioieoofndnthbffeyoorrlMihhvDuueHmmr.atanonsxs.i.cTTithyhiisasnnndeewtwumiinnoffroorrfmimnaadttiiinoognnsmmianayy have implications for the quantitative analysis conducted by MDH. revieweFFdiinnbaaylllliyyt,,s EEScPPiAAeniicseiinAndttvhhieespporrrooycceeBssossaroofdfff(iinSniAsBhi)insgihnaaldidranartafg2ftt00rr4iis.skk Taahssissseessdssrmmafeetnntrtiooskff aPPsFFsOOeAsAsmttehhnaattt wwwiiillllll bbee brbSeeeAvcciBooemwmweeeebdaasvvbiaatyiielliaat(bsbsllrSeevcottiovoe.nttchchpeeen.Appguudobbvlvli/iisccsoiwwrbyh)heeBannnodaiitriodissn(ssStuuhAbebBmmEi)iPttitAnee'ddlsatttooPeFtt2hhO0ee0A4SS~AAwBTeB,bh,piaasanngddderawwfit(illlwrlivbsbk.ee acpppsooass.setesessddomvooeonnnptbbpoowUttpihhfllotthahee). aISIRfRAtIIBSrS taawhsseessbeePssssFistmmeOeeA(nnwttSsswoAowfBf.PePrpFFeaOvO.igAAeowv.aa/nnsaddbPP/)FFOaOnSSdaaorrne taahllessooEbbPeiAinn'gsg PpprFreeOppaAarreewdd,e, bbbpuutatgwweiill(llwnnwootwt bb.eeepccaoo.gmmopplvle/eottpeepuutn/npttiiflloa/). after the PFOA SAB review'. 22000099..00005599 SSppeecciiffiicc CCoommmmenenttss PPaaggee 33:: product"TiTohhneoe fsSUupmelnmrlfanlaruryyoraaolnlcddhetthmheiecllaaaltteserr(ddPeeFttCaasiill)eeddatssteehccettiioCoonntbbtaa6tgthhe Gnuorototevttehhaasittte33.MMWhhliaaatdd ppishhnaaossteeddcooauurtt ttihhseewhether papaannrocyykdooautgtchhiteeniorrgn.PPFFoaCnCf-dpr-reewerlhlfaaeltutteeohddreoraacccthtthiievvemiritteiiiceemassalsssyttii(llPslltFicclCloonnsbt)teiinanrutueetelheaaeattsCetthshooeetftfafaagPcceiiFllGiCittsyryo,,avssseuuscocschhiiteaaa.ssteWhhdaahnwndaidlttlihiinnsggtn,h,oouutsssece,la,ecapptrrrioovicscieetwssessshiiennatggh,,tehoroerr facility. Additional clarity would be useful packaging, and whether there may still be releases facility. Additional clarity would be useful. of PFCs associated with those activities at the PPaaggee 33 aanndd PPaaggee 1166:: the struTcTthhueereddooofctcuuhmmeeencnthteppmrrieecssaeelnnsttssaanasdsssvuuemmrppyttiilooinnmsistaaebbdooduuattt.tthheeClbbeeeahhralavyviioiodrroeonftfiPPfyFFiCCnsgs tiinhneaaaiirrssaaunnmddpsstooiiiollnbbsaamsseeadddeoonn tatahonneddthsttethhrseeuecllatiiumsmrsieiuttmaaopttiftioiotnhonsnesosocf.hfetthhmeeicaavavalasiillaaanbbdlleevddeaartytaa would limited would helpdata. help ttCoo lpperraeervvlyeennittdetthhneetifrryeeaianddgeerrthfferrooammssaaussmccrrpiitbbiioinnnggs ccmeerrattdaaeiinnttyy to these assumptions. Frankli"nTTh(h2ee0AA0g2g)eennccicytyedwwooounullpddaaagllessoo16bb,eecvvoeenrrcyyeriinnnitteenrrgeessettseetddimiinantrrieenvvgiietehwweiinnpgogttethnhteeiauulnnppfuuobrbllliiosshnhgee-ddrrareenppgooerrtttrffarnrosompmort of PFOA released to air. Franklin (2002) cited on PFOA released to air. page 16, concerning estimating the potential for long-range transport of Page 4 and Page 21 Page 4 and Page 21: EPA's p"TrTheheleissmuiumnmammrayarriyyskrreefafeserrseeennsccseeessmeoonnnteeooonftf thPheFeOrraAanngbgeeasssoeofdfommnaardrggeiivnnesslooofpfemexexpnpotoassluurerfeefecccaatllsccuudllaaatttaeeddiniinnantthihemeal EsistdtPueunddAtiiie'esfssipaeardnneddalismmmaeienapasarsrueuylrrieermddiiskhnhauuarmmsysaaefnnisgsPPuerFmFeO,OeAnAatnssdoeentrruhPuemcFmaOllveeAevveaeltblsssa..osIeInfdftthhotihnissedrureasavneneoggleefopiitssmheuuessneretdada,n,lgiieett fssfdhheeoocsutucslrlddidbabbeteeda ssiipnpneectacihnifefiimiccaaalllllyy assessment document need to accompany identified as a preliminary figure, and the assessment document need to accompany ttchhaeeverraaanntsggeoe..n the use of the range described in the PPaaggee 1133:: should bIInenttnhhoeetedddiisstcchuuasssstiihooennoaofbfsaaeiinrrcemeomisfissdiseiotonenscs,t,iddoeenppooosfsiitPtiiFoonnOAttooossrooiilPl,,FaaOnnSdd sisnaammtphpelliifnnogguroofdfffe-scsipitteewewwleellslllss,,aiimttpled ddshooeoesuslnndootbterreenssoootllevvdee thethat the qqthuueeessattbiioosnenonocffewwohhfeedttehhteeerrctssiuuorrnffaaoccfeePddFeepOpooAssiitotiirooPnnFhhOaassSooiccnccuturhrrereedfd.o.ur deep wells sampled PPaaggee 2222:: enf orc "The eaTbhlee paragraph at the pcoanrasgernatpahgartetehmee bottomofthe page nbtot(toEmCAo)fpthroecpesasg.e TiihnneccoorArrrgeeeccnttllcyyycchdhaoarcraascctnteoertriizzheeassvetthhaeenEEEPPCAA'A'sswooinntgghooiinngg emt`hmnaeafnnoPuurfcFfaeaOcactAbtuulrerEeercrCssoAnaatstperttnhhoiitcsseasttgsiirm,meeeetmhffeoeorAngttthhe(eeEnCciinnyAffoo)wrrompmuraaolttcdiioeossnnusg.MMgTeDDhsHHte Athhhgaassefnddoceelsyslccordrwioibibeenesdgd.n.cohTTtaoonhgammevooserreetaonaatccEhcceCuureAraxatitweesltliyytihnccgaappttuurree tllhaanenggPuuFaagOgeeA,, shown in redline for additionsandstrikeout for deletions ECA process, the Agency would suggest the following changes shown in redline for additions and strlkco-a~ for deletions: to the existing 22000099..00006600 3 "TThhee UUS.S.. EEPPAA''ss OOffffiicceeooffPPoolllluuttiioonn PPrreevveennttiioonn aanndd TTooxxiiccs,, tthhrroouugghh aann eemnnaffnoorruccfeeaaabbclleetuccoorannesnsesdenntutsaaeggrrrseeoeemfmePennEttCs((EECCnAcAl))appdrrioonccgeess3ssMuu)nndadenerrdttaaokkteehnnewrwiitinththervveaasrrtiieooduussparties, has m bebneeaevenninurssfoatnuctmdteuyunrientrdgsatstayhhsnoeedceiiexuaxtntseteeendrgnts,tw,oiddtfiihssPttFrtrihiCbbeusumtt(iiaioonnnnuc,,fluaaadncntdidnugrffaaett3,eeM ouosf)f,aPPonFFrdCCdsoistsh((pppeorrrsiimaimnlaatoreriifrlleyysPtPPeFFdFOOCpoAAasr)r)tiPieinnsF,htChheeas ecacoonvnanvtitiaarloiibnnnliimennggeonnpptrraaoonsddsuuEoccPcttis.Aa.tAeAwldelllbwddsiootichctueutmmh(eewennmutts.sanrrcueepllfaaaatt.ceegtdduorvtteo/,ettudhisoisesc,kuuoennrtdd)ederinrsttpaapokksiinanlgg ar posted of PFCs or are posted andPFC and available on an EPA web site (www.epa.goviedocket/) (-kttp 2003-0012. ".H.e..a.s.c.a,~d,e~e.~p,a,~go.~v,i.R..i.g.~h,tLSOi~tLe~,/,~d,~kpru'ubol"i'~c-"h~o'"m'e~-..h.t..m..)) uunnddeerr ddoocckkeett nnuummbbeerr OOPPPPTT-- 2003-0012. in In this this ECA ECA process, process, EEPPAAididenetnitiffiieeddsseevveerraallnneeeeddssflobrr mmoonnititoorriinnggininflobrrmmataitioonn,, pcpinrorocomclcpueeasdssnisinyinng)gg,.m,aaanonnnddditDouuurssPiiinnongggntivvna--aprtrhaiioeoruuivssiccPPiiFFnpCCiatsys.t. oiT'Ifnhihtrgrheecteeihliccistooiepmmsrppocaacunenrsiriesesenh--s-talyv33eMMm,i,annDDduyiyfncnaeaceottouennr2di(n(awg3i,33lMlMingness `{cto0moomeennniptttaeeornrryiiinn)n,gtfooaonM MndeaemDnmoduorParaoarnnnodtduana-odopftfmhUU~eninidcdierperearssstptitneaacgnntddiiiinvnnetgghli(suM(oMprOOroUoUpScos)e)lssyxwm~ihietathhrvettmhhaieennudAAfigc~seacenttnecocdyryiafnfowogrrifllaicnilgintieesss mloocantiteodriinngDeocnataunrd, aArloaunbdamtaheainrdreWsapsehcitinvgetofnln,orWoepsotlyVmigeirnimaa,nuTthhecsteurMinOgU~shcailriefies located in Decatur. Alabama and Washington, West Virinia. These MOUs are `caanunirirnneddneetplpyeennuddneednnettr,,vnvoeolgluountntitaaatrrioyynmm.onAoint[iotboruririntnhggpcporrmooggprraaanmmya, atDtiatitsiskfifnlluuAoormooppeoorillcvyam,meeisrrundertaking `manufacturing facility, which iss uco-located with the 3M/Dyncon plant in Decatur, manu(hcturing thcility, which is co-located with the 3M~yneon plant in Decatur, vs isAl I eB s e be oa A1 b ........ " " ~ ........ 3An3oMMmlCCooneotg,eiarraggpeeiroGGdcrruoocvvaieengjffaaPcc-iFilliOita~Ay hhsoaanss-fnncaooorwttgmebbmefeeeaeercnnticliiinin-atcclylliuaumbdd-aeessPddiesrii-nnk(tetVBhhrFiis.ssbuueeDfrfPffogoom-r~Wiotenttsioontadd-kVaat,ittereU'g.bbiSee.nscciaaaE.uuPssTAeeh,eiitt is is bpnpyeoerrs3sloooMnnnagalfelorccrpootrmmhomemdu3unuMcini/cniaDcgtayitPniooFennOo,,nA2200p0o0l4n4a).)na. cTiTnohhmeDeempcpahhetaarucssrieea,ddlAaablppaappsrikrsooasa(mMccahh.iFmmn.ovonDoniloitvtmoeorsriinitnnihaggekpp,flloUaalnn.lSopp.wrrEioonpPpgooAssi,eendd nbyo p3aMrtifcourltahreor3d~ery; nWeesotnonp2la0n0t4)in: Decatur, Alabama involves the following (in no pa~icul~ order; Weston 2004): Page 24 Page 24: the 3M/SSDeeyccnttciiooonnnVVf..a,,ciiiltteietmym i11n.,, Dssehhcooauutlulddr,bbAeelccaoobrrrraeemccatteesdd t0sotilnnlooeteendttehhraattdtethhveeelMMopOOmeUUntff.oorrTvvhooelluucnnuttraarrreyyntmmosoneninitttoeonrrciinengg at at should be amended as follows: the 3MfDyneon facility in Decatur, should be amended as follows: Alabama is still under development. The current sentence CCaoponpnsrsioidadecerhraattfiioonnnesshchooeuullsddsbbaaeesrggciioyvvpee)enn ttooofddieenvvveeeslltooippgiianntggioaannnwddoiirmmkppsllieemmmielenantrtiionnggh((auutssidniegnvagaelppohhpaaessdeeddby aw33ipMMtphrffoohoarrectthhhUeei.fSDDn.eeecEccaaePttsuAusrra,,(rsyAAe)lelaaapbbasaacgmmoepasae2ffaao0cc:fii2lliii4ntt2yvy2euu.sn2ntid3dge)earrtittohhneiiwrrpoprrrokoppsooismseeiddlavrvootolluutnnhttaaatrryydeaavggerrleeoeepmmeeednntbty with the U.S. EPA (see pages 2~-2122-23). 22000099..00006611 4 `hazard a"TTnhhdee rAAisggkeecnnoccnyyclhhuaasssinnoonotst ccdoormmamwmneenbntyteedtdheoonnMttDhheeHttoobxxeiicccaooullosogegiicEcaaPllA'aaccsccouurrwaanccyyoriosfkfttahhseeserreesppsoomrrettnootrraocotnnivttihhteeies on the PFCs are still in progress hazard and risk conclusions drawn the PFCs are still in progress. by the MDH because EPA's own risk assessment activities on CottageHHGoorwwoevevveeerfr,a,cEiElPPitAAy wccooonnuccluudrrsbsewwivittahhluMMabDDleHHintthhhaaettlaapddidndigittiitooonnuaanlldmmeoronsnititatonordriintnhggeiisnnoffuoorrrcmmeasat,tiioponnatcchoownnaccyeesrrnnoiifnngg tthhee eCexxopptootsasugureree,G, raaonnvddebbfeeahhcaaivlviitiooyrrwoooffuPPlFdFCCbsse iivnnalttuhhaeebeelnnevviiinrroohnnemmlepneintn,tg. to understand the sources, pathways of mystaffI1b1fyyyooeuumhhaaialvveeataadnnoyymqqiuuneeissattkiioomnnassrccyoo@nneccpeearr.nngiionnvgg,tthhoeerbsseeyccootmemlmmeepnehtnostns,,eppalltee2aa0ssee2-cc5oo6nn4tt-aa8cc1tt0M4M.aarryy DDoommiinniiakk ooff my staffby email at dominiak.marv@epa.gov, or by telephone at 202-564-8104. SSiinncceerreellyy,, w/s/ CCOfhhfaairrclleeessofMMP.o.lAAluuueterir,o, nDDiPirrreeeccvtteoonrrtion and Toxics Office of Pollution Prevention and Toxics 22000099..00006622 ODSEPPAARRTTUMEENNTT.: oneDATE: 0.TO: PPOOLLLLUUTTIIOONN CCOONNTTRROOLL AAGGEENNCCYY August 12,2008 Augustl2,2004 sim Kelly, Minasota DepartmentofHosts Jim Kelly, Minnesota DepartmentofHealth STATE OF MNESOTASF-00006-05 (4/86) STATE OF MINNESOTA OOffffiiccee MMeemmoorraanndduumm PROM.FROM: SDSDSuauuavpppvioeeiddrrtftouDDnnonouddduggUSUllancnasishi,t,o22PPnS/rrSouojupjeepeccesttrtfM MuuannaddngaSSegeeerscrtiioonn fone. Mdaojgorasiasnd Remedistion Superfund Section Majors and Remediation Division Division PHONE: 296-7818 SURECT: SUBJECT: 3C3MM Chhemeolitme/HHeeaoalltthhClConosnuislutltaatttiioonn This memorandums writen inespons 0 he Puli Comment Relss diff te Hlth This memorandum is written in response to the Public Comment Release draft ofthe Health Consultation for he 3M Cotas Grow Fly. dad Jun 4, 004. Tank you or coniering Consultation for the 3M Cottage Grove Facility, dated June 24, 2004. Thank you for considering MimesotaPlhin Con Ageney (PCA Sa crmens oh previon rf of 4s Minnesota Pollution Control Agency (MPCA staff) comments to the previous draft of thi s Gocument. Th lowing re stem MPCA siacomment 0 ot he 26 drt or document. The following are additional MPCA staff comments to the June 24th draft or Careatonsofpreviow MPCA saffcomms clarifications of previous MPCA staff comments. Summary, pag 3, frst paragraph Summary, page 3, first paragraph From previous 3M brfngs 0 MPCA and MDH af, isthe MPCA sas understanding thax From previous 3M briefings to MPCA and MDH staff, it is the MPCA staff's understanding that NTcomme to maniacies Axor tt gh <orbon perucrochemictl (FC) Scotch 3M continues to manufactures and/or test eight-carbon perfluorochemical (PFC) Scotchguard TrTe hing foun tthe city T1VIDH is nt veil the itsofi dion he MPCA fire-fighting foam at the facility. IfMDH has not verified the status ofthis situation, the MPCA SaifSos ot he MDH est hi 3 deny he chemi Formal fo 6. ghing staff suggests that the MDH request that 3M identify the chemical formula of the fire-fighting Toa tad the Fcilty and 1 Sats regen manufacture and ting hy foam tested at the facility and its status regarding manufacture and testing at the facility. Sumter, pags 4 ast paragraph, stsentence Summary, page 4, last paragraph, last sentence The MPCA staff understands hs his stement fs ltd to cls ations for vain isk 36 The MPCA staff understands that this statement is related to classifications for evaluating risk as Seif by th Agency or Toe Subuanec snd Disease Regi (ATSDR However, ached specified by the Agency for Toxic Substances and Disease Registry (ATSDR). However, as cited 1 Append ne MDH ha deloped Hens Based Vals and So Reference Vues or in Appendix 1, the MDH has developed Health-Based Values and Soil Reference Values for FOS and PFOA. 31 as fund PEGS and PFOAIn some parpout wel soofnwhisch hve PFOS and PFOA. 3M as found PFOS and PFOA in some pumpout wells, some of which have en ued as fly enki we wel se Table yan in ground water pe 1c D1 at eels been used as facility drinking water wells (see Table 1) mad in ground water near Site D1 at levels i exceed hf respective HBV. 1 th MPCA sll' nderanding rom 3 biog tht that exceed their respective HBVs. It is the MPCA staff's understanding from 3M briefings that SN cmploees have sented ly ining water xcecding hr seeive HBS. Aa 3M employees have consumed facility drinking water exceeding their respective HBVs. As a esl, or some ime 3 ha provided bore drinking war 1 cy employes. The result, for some time, 3M has provided bottled drinking water to its facility employees. The NPC sf as clsiied PGS and PFOA a MERLA haus stances and concider MPCA staffhas classified PFOS and PFOA as MERLA hazardous substances and considers ingestion of hve chemil at eels shone ht spective HBV o represen smceepabie ingestion of these chemicals at levels above their respective HBVs to represent unacceptable ik nhs corte nd fr he scr, the MPA Gl i ancedssshes eta hua risks. In this context, and for the record, the MPCA staff is concerned that these actual human rts fom commaeed cy knwerere waceaPobls prm exposures from contaminated facility drinking water represent unacceptable human exposures to se PFS ad ht hseexpanre do nt reece a -ndleminte pub EA AG these PFCs and that these exposures do not represent an "indeterminate public health hazard." Supertund Sie History, pe 7 Superfund Site History, page 7 The MPCA il equ ht atv bs die er cle nthe document (is ot The MPCA staff requests that narrative be added here or elsewhere in the document (if this is not he appropriate Pact) ha capares h Flowing: the appropriate place) that captures the following: + PtFhC,reimneadiraylmienvdes:tigatsionn rmination ited in is ection id not focus on the remedial investigation and remedial actions cited in this section did not focus on PFCs in any medium; RECYCLED PAPER WITH A MINIMUM OF 10% oS POSTCONSUIgER WASTE 22000099..00006633 + aiacncovoensnstseiengnatttoioodrndeearrnadaddrddeeemnneddduiuamml iiascbbteeiiinnoggntosnneefggoootctiuiaastteoednd t0PoFmmCaoddiinfiyatlthhmesesdccioapoaeototpfhfttehhefeacrrieelmmiteeyddiaianalld inal minevdeisatigwahteiroen aPnFdCsrewmeerdeiaolraccotuiolndshtaovefobceuesnornelPeFaCsesd;in all media at the facility and in all + tm"thhneeeesdsueetiarsiawileteihszseearadrerehPyrrFdeerClloaasfttelewdudoe0trroeticthohearercoosold"udladccnoohdnnassveenenttbooerreddneerrrewwlehhaiisccehhd;mmeerreellyy rreeffeerrss ttotthhe ddiissppoossaall ooff ana"calnonyneasutlyetirtnciatcalaiolzlremdmdeeerththyhwodoaddrsosseftltxouoeocdduriiitsscettditin.angrgsuu;ii"sshhaniidnnddiivviidduuaall PFCs PFCs were were not not availble available aatt tthhee tiimmee tthhatt tthhee consent order was executed. SSiittee DDd4:: PPhheennoolliicc W Waassttee PPiitt,, ppaaggee 8 T2T6h.hee TM Mt PdPoCCsAAe nsstotataffaffhphpaaeddarpprrteehvvatiiooMuussDllyyHccaoodmmdmrmeeensnstteeedddtoohinnsttchhoeemppmooesssnsiitbbiiillitttyyhoeofPfdoPFcFuCCmevvnaatp.poorr1iinFnttMrruuDssHiioonnbeiilnnieBBvuueiisllddtiihnantgg 2vves6aas.ppeoonIrrttiiidnanotlterrlusuyssniinoooonntn-aoovpffotplthheaiatissirltbbehuu"aiitlliddnMiitnnDgghHiisfsiarnndsootdttpraseannsrsaiiegssdsrsuautehpehi(o(sMMfcoDSDmeHHcmtnnieooonttntessi1n1tth.htahatDetittdshhcoeeucvvsuoosmlilaaeottinnill,tii.tttyyhIfeoonMff PPtDhFFeHOOMSSbPeiilCssieAvessttahfat "reescsoemnmtieanlldysntohnt-vtohliastirleea"soinnithnge be ariclated i th document. first paragraph of Section III. Discussion), then the MPCA staff recommends that this reasoning be articulated in the document. A`Arreeaassooff PPFFCC PPrroodduuccttiioonn aanndd UUssee,, ppaaggee 1100,, ffiirrsstt ccoommpplleettee ppaarraaggrraapphh Docs MDH believe the release of PFCs to the atmosphere represents threat 0 pubic health? Does MDH believe the release of PFCs to the atmosphere represents a threat to public health? PPFFCC M Moonnititoorriinngg aat tthhee SSiittee., ppaaggee 1133,, istfirst ccoommpplleettee ppaarraaggrraapphh eDDfoofnlnueiKLnrtriieeonnfssMeooftfrttohhepeoM lMiPtPaCCnAACossuttnaafcfffihlha'asss EbbaeegeelnneccPooonnittnaatccttWeeaddsaatbbeooWuuattttheheer ppToorssessaiibtbimilleiinttyyt ooFaffciPPlFFitCCy.ss bbTeehiinenggMiinPtCthhAee staff effluent of Metropolitan Council's Eagle Point Waste Water Treatment Facility. fwaiclillkiteyc'speMffDluHent.informed sbthoeouutcotmeofany efforts to determineifPFCs will keep MDH informed about the outcome of any efforts to determine if PFCs ae in this The MPCA are in this staff facility's effluent. Please collmeat (651) 296-7818ifyou have any questions concering tis memorandum. Please call me at (651) 296-7818 if you have any questions concerning this memorandum. 22000099..00006644 . Pras W=gCtaono. _u.tn. ,ctmyty = = p= 4 wean HDDeeeapplaatrrhttmmaenendnttEoonffvPPiuruboblnliimccent Health and Environment ot Ma~y L. McGIothlin Louse Director Lowell Johnson Deputy Director AAuugguusstt 1177,,22000044 JJMaaimmnenesessKKoetelalllyyDepartment ofHealth MSSDiIittiEeennAAesssssoeetssaTssDmmPeeenpntatraatmnnddeSnCCtoTononEsfsu2uHll0letaaatltitoohnn Unit Unit PPS1a2OOi1nBBtEooPaxxastu66l744th997M7P551N STE 220 $5164-0975 Saint Paul MN 55164-0975 RE: Health Consultation - 3 Cottage Grove Facility (aka 3M Chemolite) RE: Health Consultation - 3M Cottage Grove Facility (aka 3M Chemolite) "TpTrhheaapnnakkreyydoobuuy ffotorhretthhSeeitooeppApposorsrtetuusnnsiimtteyyntttoo accnoodmmCmmoeennnsttuoolnnattthhoeen cIUIaenliatlttohhfCCtoohnnesusMulitltnaatntiieoosnnotffaoorrDttehhpeear33tMMmeCCnootttottaafggHeeeGGalrrtoohvv.ee Sit, Sitc, prepared by the Site Assessment and Consultation Unit of the Minnesota Department of Health. oPPrfriiOooprrettrooatffiiinnoaanllsiizzaiinnngdg ttMhhieecChCoaoueunlntStyya'n'sstoccrooomm,mm3eneMtnstDs,i,rMMecaatrroyyroMMfecGEGlnovlotihtrhlolininnmeaannntddalI|,mmHeeett with awli,th Fred Luden, 3M Director SFarfeedtyLaunddenR,e3guMlaDtoirreyctor Affis of Operations Affairs. and Michael Santoro, 3M Director of Environmental, Health, Safety and Regulatory "TCTohheme mmmaeajnjootrrii6ttyyoanofdfttchhoeemCCmooeuunnntttyy''ssalccsooommamdmedernnettssss rrveeolllaaatteti l0toe otthrheegarrneeillceeaacssheeeomoiffcPParelrfsfll(uoVorOroCocsch)he.emmicicaallss (PFCS). (PFCs). Comment 6 and comment 8 also address volatile organic chemicals (VOCs). Our comments are as follows: Our comments are as follows: 1. 1. 3C3oMMntssahhmooiuunlalddtimmoonoddoeefllfstthihteeehhiissattsoorriimccoaadlleialirredeemmiinissss1ii9oo9nn1ss)ooffBPaPsFFeCCdstotoonaacrcecscuuurlartastteefllryyomddeettteehrrmamiiinneecipposossissoiibbnlleemodel, 2. tcth3hoeenMtssaosomihlloianaunnladdtdiogigndrreooonuutfnnif-fddsywwiatteathtee(erlreaxsiitntnemttnhhtoeedossfeeecloooefndffft-siasnimitti1een9aaa9rrt1eei)aa.ossnBsshihanoosguuerldlodduonbbndeewreteaesstsuteteelrtddsffffrorooorrmmppoootstshssheiiebbarllieerrecceloomennaittssaasemmisoiinnonanamtthiioooednne.l, 2. pTp3rerMoopppleeasrrhctyeoy,mu, eliidnnn,ccidllauuenddndiitninffggyottthhmheeetaaehccexccitiveddaneerntnitotoaaufllscrrodeenllueetmaaamspseeisnffitrareotsoim.omnBB3ilMnddggsrh11oo55uu,,nlddddiiwssiccanoostevtvraeelrrfeeraoddmrdduuoirrtiihnnaeggnr dssrleeeowlwereearsrsoeppusiirppoceeen the pump 3. ro3oeuuMpttlwwasceheeollmlulsledtnoti,pnpsrarteenavvldleenfnarttdodccmiootnntithtoaaenmmavilinanmaraiototniiuoiostnnodffruriromnomgmpwmmseiootlvevlsii.nn0gg3oMfofuflfssl-hysiioctcu.eh.ladraicntsetraillzebatrhreieerxtaenndt!oarndsomuarcgeniptuumdep 3. ao3olfMfrcceooasnnhdtytoaaummilindenixnaiiatnstisitotoeannnl,l,caeiin,dnccdtlliuhtuidedoiirnnnaglgolcmmmaotonionoinniti,ttooorrdriiiennnpgggthwwweaelelnlllldsss iPntnoFttCfhhueellleppyvlleuuclmmhseae.sr.haocI1utffelaradiddzdbdeieitttiihnooeonntaaeellxdtmmeionontnitahittenoodrrHiiemnnagglatgwwhneeilltlussdaaerree 4. C3aClooMrennasssduhayolttuaiilntoidoenndx.e.isvteelnocpe,atwhaetirerlomcoadtieoln,tdoeipntthegarnatdePgFrCounledvwealtsesrhoaundldsbuerfnaocteewdaitnerthfelHo,ealth 4. 3iiHnnMeccaoolsrrthpphooorAuraasltdtsiienndsggsemvttheehneleotff.piinnaddAwiincnaggctsseoororfmfdMMioodnoosegslsstlitoehrrein((H22tee00ag00lr33ta))hteaaAnngsddrsoeBBusanasrrmderewnEEatnnt,gegiritnnhaeeeneedsrroiisnunugrgrcf((ea22c0o0ef0033wt))aerrteeecfruferefrrlreoeennwnc:c,eeSddViinnmttohhdeeel iHs euanltkhnoAwsns,esasnmdentht.e dAactacoarnddinagsstoumtphteiHonesaluthpoAnsswehsiscmhenittw, athsecsroeuatrecde aorfethaelscounroretnktn3oMwn.model is unknown, and the data and assumptions upon which it was created are also not known. Coverment Ctr - 1408 210 Sst ot--h .0, Bo Sitar Morasta S5002.0008 Government Center 14949 62nd Street North -- P.O. Box 6, Stillwater, Minnesota 55082-0006 ones G5 430555 Foc E5143087% TY. $514300346 Phone: 651-430-6655 Fax: 651-430-6730 TTY: 651-430-6246 vag www.co.washington.mn.L~s East EncimonOrpen Amato Acton Equal Employment Opportunity / Affirmative Action 22000099..00006655 55.. 33inMMclssuhhdioonuugllddbiggoaaaiincncaaumbbueeltttateetrriouunnnddaeenrrdss/ttoaarnnddbiiinnoggmoaogffntithhfeeicffaateteiooonffPiPnFFfCCisssh,ddpiisescrcshhiaasrrtggeeenddcettoointthhbeeotMMtisiossmsiissssesiidppippmiienRRtiisvv,eerr,, 6. eeiInttnc.ca.lduddiitnigonbitooaPcFcCusm,utlahtrioenaraenda/onrubmiboemroafgrneifliecaastieoson finVfiOsCh,sperresfiesrteenncceediinnbtohtetodmocusmeednimt.entTsh, e 6. 7. 3IiimnmMppaadasccdhttiootuofioltfdnhthecteososoeePrFrrdeCeillsene,aaaststhaeeeessrsrsehhoaoourunueldlddoafbbnegeurfmfouulubllnelyydr wcocahhfatarrereaarlcecstataeesmrreiipszzleeoiddfnVbbgyyOo33CfMMas.l.lremfoenreintcoeridnign wtehleldsoacnudment. The 7. ppP3rrMFooCddsuuehccxottpiiuoooldnnsuwcwroeeeolllfrlsdriottnoomabbtieeentgtatteeesrrrotiuuuonnnndddoeefrorsdsftt'rgaairnnnoddkuittnhnhdeegweewaxxatttteeeernnrtstoatomoffwpggolrrrionokuugennroddsfw.waaaltlteemrrccooonnnitttoaamrmiiningnaatwtiieoolnnlsaaannndddeexxtteenntt ooff 88.. PAAafnFftdtCeerrreettxrmrepoeaoavtstmeumreeaennnttyfrppocoomnndtiosnaamgarierenesnaatiabtobaenadndndosdofoolnds.nereidnd,k, i33nMgMswshhaotoueulrlddtotteewsstot rttkhheeeprspo.onnddsseeddiimmeenntt ffoorr VVOOCCss aanndd PPFFCCss,, 99.. TTsahnhhodeeurllleodomccbaaoettviioaoensnoasonefsfyosotecthdohenefrtroarddmiiissimpnppooaastsceaatldl 0sssiiotttieelhss.essehhnoovuuillrddobnbemedeidnstis.cclloo(sseee.dd.bbyPyF33CMMs..arTTehhfeeossuiinttdeessiiinddgeernntotiiuffniiededwdabbtyyer33MM 1 0. C`ssshaoamnomcuppellldneetssbreaiinntaittshohsneeessoLLsafeakdkPeefFoJJOraansnimeeapLLnaadancndtPdftifFoilllOtlhaaAerreeeaaanr))evisriognnmifeincat.ntl(ey.ga.boPvFeCtsh are found in e Minnesota groundwater Department o f 10. CHeoanlctehnhteraatlitohnsbaosfePdvFaOluscasnd(HPBFVO)A.sTahreesCiogunnifticyainstlcyonacbeorvneetdheabMouitnnleosnogttaeDrmephaeratlmthenetffoefcts to 11. 3H3BMaMesaeleetdmhmophnpleoatlylhteehoeasbybaaabnesnrdedeedtvtihhvsaeeatlefufdauetstseu(ooHmffmtBthhaVeersyPP)o.FFfTCChssteoiixnnColtothohugeenitcvvyaaalrriiisoaocunuosdsnmmecpeeeidrddniieeaamdi((oaaaiilbrro,,oguwwitacataltoelenr,,sgtssutioedliril,m,esbbihiiooenttaaatl,,hthehhuuHemmefafanealsnct)tshs,).to 11. d`BCCeaooasnnteshsud,ulltrotaaenttpiitroohonned,,uaicibtttbaaiprpvepepveeaiaaanrrtdsseddtthehseevurreemeloaamprreaemreaayntnnoauuflmtmobebxfeeofrreolcootfgsfp,ipcoiosanssltsieaibrbnlfdleeerehehpneeicaadellettwhmhitoioouhulttocccghoooimmcleaeeslss,t,setiriunondclcilleumusdedtiiinnangbgthoccelaainnHsccmeee,rar,l,tthc. ddW Wreoiaorntrkhkke,iernrrsgsepwhhraaaotvvdeeeru.chhitiiss3vtteoMorraiiscnchaadollluldyyledbbveeeeeelnonnspueemrxxeeppntoohtssaaeetlddealbfblfooewttcohhtrsook,nneinrttthsheeerafjjreoeorbbednraaicnnneddkwibbnyyigthiiwnnacgghteeeossrltteiinfsnrtggeeeroccoooflnnmttPaaeFmmtCiainsnbaaotatleiensdddmV, OetCcs. drinking water. 3M should ensure that all workers are drinking water free of PFCs and VOCs. 1fyou have any questions regarding the above comments, please contact me at 651-430-6703. If you have any questions regarding the above comments, please contact me at 651-430-6703. Sincerely, Sincerely, CCPirinnoddgyyraW WmeeMcckakwnweargetrethrh,, RREEHHSS,, MMSS Program Manager : C: JMMiyymrraSacPPheeuttgee,rrssCooonn,u, nCCtooyuunAntdtmyyiCCnoiosmmtmrimastissosirioonneerr JMMFiramaerrdyySLcMMuhcducGegGln,o,ltCohDtohliurilinennct,,ytoDDAre,epdpa3marMrittnmmiesetnnrtattDDoirirreeccttoorr FMMAfirfeiccadhhiaraLeseulldSSeanann,ttDoorrioore,,cDDtoiirrre,ecc3ttMoorr,, 33MM EEnnvviirroonnmmeenntt,, HHeeaalltthh,, SSaaffeettyy aanndd RReegguullaattoorryy Affairs 22000099..00006666 ODinn city of Cottage Grove ms 0 August 16,200=I my Mr. James Kelly ST Sin Site Assessment and Consultation Unit Masa Minnesota Department of Health Te 121 East Seventh Place ye P.O. Box 64975 COE rs St. Paul MN 55164~0975 RE ------ RE: Public Health Consultation - 3M Cottage Grove Facility pester Dear Mr, Kelly: Sy mas gp tye The City of Cottage Grove has reviewed the public health study of perfluorochemi~ls Br re: (PFCs) at the 3M Cottage Grove Facility. We understand that monitoring the impacts ot Te Ee a, of PFCs and other substances present at the site is the responsibility of the Mir~ne~,ot~ Pollution Control Agency and the Minnesota Department of Health. I ---- The study indicates that there ar~ no known immediat~ health dsks for the larger coma munity from past discharges at the Cottage Grove facility. This includes no known cona ee ek, To Ser tamination of wells in the area surrounding the 3M facility. The City does support the et term St sw os recommendations included in the report, particularly the need for continued monitoring a eer of potential I~eatth impacts from PFCs a~ the sile~ aE Thank you for the opportunity to comment on the report. We would appreciate b~ing T snc R, notified of the results of future studies on the 3M Cottage Grove Facility~ aieo,STN ` Howard Blin Th = MooemicShcoamvis Community Development Director co: Mayor and City Council Ryan Schroeder; City Administrator EQUAL OPPORTUNITY' EMPLOYEf~ 22000099..00006677 5M Gesan Offs 3M Genetal Offices AAuugguusstt 2200,,22000044 sw cane: 3M Center St PauI, MN55144-1000 mine 651 733 1110 !MSVirItI'e JJAaasmmseeessssKKmeeellnlltyy and Consultation Urit `ESEMninitvveniinArreoossnnsommetesaensnDmtteaaelplnuHHtteaeamnaledlttnhhCtDDooinifvvsitHitsseliitaoaolntntiohn Unit Minnesota Depattrnent of Health VViiaa EE--MMaialil:: jj aammeess..kkeellllyy@@hheeaalithhssttaattee, rmrmn.uuss Re: 3MColtagoGrove,MNConsulaton Re: 3M Cottage Caove, lVI'N Consultation DDeeaarIMMrI.. KKeellllyy.: consula33tMiMonaapprpepprroeerctci.iaatteAessstthyheoeuooppkppnooorwrtt,uunn3iittMyy thoasccobomememmneeswnottrooknnintthgheeaMMnidinncnonenestsoiotntaaueHHseetaaollttwhhoDrDekeappcaatrlitlvmmeelenyntw't'isstddrraatffthte M CMcooitinnntnsnaueeglssetoaotGttiaaroonPPvolreelllpusiiottrieoot..nn WACCoesonnythtroarouovllekAcAnagogreewenfn,uccl3yylM(y(MMrhPeaPCsvCiAbAce)w)eenaannwddtoeHHrkeediranaalgftlhtacDDnoedenpspcauaolitnttmmtaietneinunotetnst0roteoapawddrdc.orhreekssWssaeciisstvsisveuureesylssymaawttutitchthhhee the awCappoopputrrtleaedcgciielaaittGkeeei~ttth)hveeeoDDsfeietfpep.a.atrrhW ttemmfeeeonnhlttal'svsoeweeitcfnfafbgtcot'etorsfumttolsomlyeuunrnnetddvseeirlessowttnaaenntddhdethtthhceeeo&neecxxaltfuteetsnnicsosoiienvvssee,uddrltaaea`tctaaioobbmnaamssreeeenopodnnmatftM.liuuoooWnrrsooeceahvhneeedmrmiyecixmeatalulsosc,f,thaahnnedd wrhdaraoavuffetldrzaeeldppikooreaittntoiionnpoaapfnnofereetrffutffnhooirertttfytoootlloaaossrwsseiiivssnittgeyywcooouutmhiienmnsemmeacnaltoksimionnmnggettnthhhseee,ddcoo3onccMuculmmwueoseniunotltnadass,lraakecceccco0umularmmteeeeeaantsdwpapiootitssoshsinibbyslloeeau..n. danOtOednnxcyctoeeouyfrytoohuue colleagues in order to cspond to any questions you have had an oppoltunity to ieview these comments, colleagues in older to zespond to any questions you may have 3M would may have like to meet with you and yore' CCOOMMMMEENNTTSS OONN TTIIIlEE CONCLUSIONS CONCLUSIONS informa`tTTihhoeen"ssttiaantteeaddmccoounncclmluussobiifoonnesscaoorfsftthheeWdderraabffettlcciooonvnsesuutllhttiaasttiiiosonnanrreeoppvooerIrttlssyuubggrggeoesastdt ttshhteearrteeeimissenaat""wllaahccikkcoohfff'aaivvlasaiiltlaaobbllee iankfeolminatotioacnc"oiunnta nhuemtbotearliotfy'onfaetahs sWcientbiefliicevienfthorismaistiaonnorvoegralrydibnrogafdlusotraotcehmeaemnitcwash.ich fails to take into account the totali,ty of the scientific infolmation regmding fluorochemicals. = AcAlolttnhhcooeuumggehhdtthbheeyddtooheecmusmwmeeenentptistntaagtteessstattthheaamteitnttaasddidrnettehssessecessonoocnlnluylsttihhyoenCCsooottntaapggaeegGGerl2oo4vveeressgiiatteer,,dwiwneeg aarleleack of utuchnonedndecegreelssrnttneaaernnadddlbiinpnyoggpthuooleffafAstlwuiuoooernethoopaccihvnhegeemmbsieticaceataelnlmotcoexhxniaictrcsiaitcitnytyetaarhninezddecdggo,eennnacenelrludaaslltiohppenoopspuusuolelnaaottpfiiaoosgnneecer2xxu4ppmoorcssemougneaec..re.dnitEEnrxgxapptaoiooslsanuuclcdkeasstoat(fo0 tt0aohsesiseeegsffesllemnececetntltaee.lxxpppoo3opssMuuurlrhaeeatisffoi'omnoommhnaiaavtllleorppbeaaedttehhntwwscaahwyyoassrrreakecdedtureucsrcieez-s-sedttthh,heeeanumudnoncsctehtereltitaaugiishnnelttyyoyftteyysxppepiii~cocmasallaelldyycopffonboptcumuenlnddatrtiianintoieeonxxn-ppfoodsosauurtazree vSaosdvesvereres2s2sm55e eycynleeiatan.rtissc,3,aMlaannfhddinaffdsbiomunugnnosdd,nnnidtooeosrccpeaaidutuseisatassllewc~raeoulrtmakotecinorossnnsch-he-iniptpthrbbeaeetmttiwwooeensestennhwiffgollhuulofcy0itoetocxhchihpeceomemsoieifcdeaamlplooeerpxxeupploooasrstuiudorerneersa-a-onnffddor' `amdavgenristeucdleinsicabl fitnohdeingvgesn,eedaelsppiotpeulseatruiomn.coTrhteeenetpriadtieomnisoltwogoictodtahtraeedoorn' omtosrueggoe~sdterasnoyf adverse effets on the general population magnitude above the genelal population.. adverse effects on the general population ffTrrohomem efuplouirdooe~mcchhieoemlmoigicciacallsds.a.taTTdhhoee nttoooxxtiisccuooglloogggeiiscctaaallny 22000099..00006688 AMMuaag-.uJJsaatmm2ee0ss,KK2e0ell0ll4yy Page20f32 August 20, 2004 Page 2 of'22 didnaadttaeabpbeaanssdeeeoonnntlPPy-FFtOOevAAieaasnrvddedPPiFRsOOkSSasiissseccsoosmmmpeprnleethhseenfnsosirivvbeeo,,thaannPddEffOoorArmmassnttdhheePbbOaaSssii.ss ooffWoriobtbuhussr,te,spect to PiPtno~FdPOOeeApAr,ef,nlsvsdeeoeercnoBtBoluycutt-teraeernndvchaaieootwefff,eee"dttRaaIelli,.gs.,"kuC"laChasathsorearssrycasmtcTetoeeinrrzitziasatcftiooioolrnnoboogo&fftyhRRPiPihssFkkaOrffAoomxraaGGncedenonePlerForaaOlglSyPP..oo3pp9u:uW l3l6aa3ti-tti3iho3o0nnre(EEs2px0xp0ep4coo)tss,utuorareend taffooonrrdPPPietRFrfOOlSuSSao,l,ltossseeo,ce"ct"A"aEEunngnovuvaisitrretoo,"2nn0mmR,eeen2gnt0uta0all3al taao(nn3rddyMH,HTeeoa20axl0litt3chh)oA.lAsossgAseyses&ssrsmemPpeheonrnatttremffdooarItchPPoeerelroer,ffgll~muuaoo3rrr9ogo:ioo3nec6tst3aa-onn3fec8eSS0xuup(fl2ofoo0snn0uii4cce),AAoacrcniiddd tstahuhnebeds99tia5t5snthtSippaaeellrrtcsce,e"TnnhtAtieilluseeegggureesintnkee2rl0aaas,lls2ppe0oos0pps3umulel(aan3tttMiisoo,nnp2rsso0eev0zziu3udm)me. allAeesvvsceerillesespnooocffeibt-beboodattshhthePPde~FFaeOnO,aAmAlyasaalinngsddinoPPsfFRaoOlOflSSetxhamepreecdsautar,e fbr' and ssuhboustladnptiraolv. idIheeaselezveislkoafsassesssumraenncteas pro1vitdhee alascckieonfcpeo-tbeansteidalainmaplyascits oonf athlletgheenedraatal, and population. should provide population. a level of assurance as to the lack of potential impact on the general * Theconclusionson page 24 futher tat tht there are limited eavironmental cata ~aaGvfvrhaaoeiivllcaeaobbnfllaeeccliaaulnnsidditoyttnhchsauunossnnttohhpteeabpgpeooettae2esnn4stteiifsaausllletiihdmmeapprtaasctcthtatitsooennttihpmpaeuu.tbbltlhiiTcechrhheeeeaaasrltl'tetahhtlieffmmlroeiorntmaetdrrteehelianectvaas"isleteohssneaamstt tetthenheetcauCClrodorteatttntaaatggleey 1IGeerpporrveesseeefnnattcssilaainntyiincndadneettneeoirtmmbiiennaaattseeseppsuusbbelldiiccahht eethaalilstthhtilhmuaaezz.aarrdd]7""heiisssootavvteeerrmllyyebnbrtIootahadadt gg"iitvhveeennsittthheeecddmaatztaaenaatvvlayaiillaabbllee DDinaafttoaarccmaaatnnia"oalnlwwaaabyyossutbbeethssesaiigdde(ot0olbobegeylliaimnmiditteehddy,,dbbruuottge33oMMlobhgaaysas obbtahtaiinsientde ssauunbbdsstttaanhnttieiaaflflectiveness. ~ooaffnn'tdftohhcteemonooasnntisi-odsienittreeaabbwwloeeeludlltlatppthuuaeommgpnpeiionntlgghoegsspyyyrssaettnesemdemnhcttyoeodccotofoonngPtterrFoooOllloSoogffayff-r-sasdiitttPetehFmmeOoosvAivteeeammtaenetndhntetthoosiefftggeerrfaofoneuudcnntddtivwhwaeeatnteeersr,s, `pabphnehedyynsseiicoscaahnllasriaadenndeddlwaccibhhtleeehmmdMiiaccBtaaalCl oAccnhhaatrhraaecctpteerreliisssettiincccsseoofofftthPheeFssOee SssuuabbnsstdtaanPncIce~esOs..A. aTthtihseisnifteoramnadtithone Th~s information has. has been shaled with MPCA. dIThehece~ardeeeiisssonnpeooreeavvtiiedddeepnnrccoeedouofcfftlliuuooonrmowccehhleelmmsiwicehaaillcsshiinncrnneeeaaatretbbayycoooffnffesioittfee wwdeeelplllrse,,saasnniddon33fMMor has has for dggtrelhocoeuaurndniddeswswanoatopteeierrnrdaeeitmmecadaantnpiaaorttoniidnntugghacffttiirogoomrnmowutthnkedeellwdsdaeetwvveeherlilcoomhppieegcddgrpaepotaroitteroitnioaonfcnorooofnmfettthohhfeee' dppperrl'opoapnpieeters~tistysi%.oancAAoftotmrphthliiessttteiidmmee,, exposure pathway. there is no indication exposme pathway. that g!otmdwater migration fi'om the plant is a completed FdPuttriIt,hhseeaicmmooorlee,na, sttthhoeefippDrlnooeddcuuueccmtetibiooednnroof2f0PP0FF2,OOStS-h-uaasnnrddedPPuFFcOiOnAAg-rrreeelllaeatateesdedsssfuubrbsostmtaannthcceeessprwwoaadss.uction pdrioscceosnsteisn.ueTdhaes aocftDiveacteemd cbaerrb2o0n0f2r, etheumsernedsuycsitnegm~feorlespsleasntfrwoamsttehweatperrodduicstcihoanrges mentioned processes. mentioned in the d:aft consultation report s fully operational. The activated calbon treatment system for plant wastewater in the &aft consultation iepott is Ihlly operational. dischalges COMMENTS ON THE RECOMMENDATIONS initiate"dTT.hhee ddalafftt ccoonnssuullttaattiioonn report repoxt zecommends recommends a a nnuummbbeerrooff steps steps that that 3M 3M has has already aheady initiated. = W Wtohhioilblteeaaianssaiigdgndniiifftiiiccoaannnattlbbdooaddtayyaoofftd'dhaattasathheaasa3allMreeasadduypybpbeoere~sn'nassuupbhbammsiietttdieddapttpoorttohhaeecMhMPtPoCCiAAn,v,es33tMMigahhtaaissonaagga~rt'eeeedd tt`tohhueeoorssboiitteace,ih,neaamannidddcdalliaatlisssott naffktaalllltldhsseauutsbbaimmtaietittttt-heeeddinsttociotleMMudPPi3nCCMgAAtshuaaepnncpaaooggorg*rgrdsreeiasnsssapiithvveaeedsttegiidmrmoaeeulplniipndnrewe'oa~fatobcerrh'rttthhsoeeeiaiinnnnvpvvleeeisssntttigiigggataathttieioioondnnaafootftf report recommends. While wedo not believe the approach will mistorprecisely the fluorochemicals at the site -- including the OOOldinmed gloundwatei Salnpling the draft report reeornmends.. While we do not believe the approach will minor precisely the 22000099..00006699 AMMurrguTJsaatmm2ee0ss,KK2e0ell0ll4yy Page3 of 22 August 20, 2004 Page 3 of 22 activites at M's Decatur site (given the different current and historical operations, c`papochhtmyyimsvsiiiiccttiaaetllsecsdaiettttti3oinnMfggassr',s,thrrDeeeremmeieeanddtviuieaaIstttsiiioiogtnneataa(icgcottiniivvveaiinnttiietshs,t,eoaadennipddfpfdrediorifpefffrneeitrraeectnnuettrarr~eceentggitutolfanalnastdtoorhryyiscctooonrntitceexaxtltsso))p,,e33rMaMtioiissns, committed to fmflle~ investigation and to appropriate actions = With regard to the recommendation that 3M should ake action to ensue that Cottage GW GerxolciotvehvseesmwowogfroaHkrrkdeeeartrlosstthaah-rleeeBnarnoesoctetoedemxVxpmapoloseusneeeddsda,tttiootohnffellutuhdoooarrotcoeu3chmMheeemmnsithiccosaauhllslosduvvltiidaaakattehhceeakcnwwtoaiaowttenle:ertdossguueeppnppstlhtlyaya'teaat3tthttMhahetehCaffaasocctiaitllaiiigtetyyeadiinny etaxkceenssstoefpHs teoalpthro-BviadseodboVttalluedesd,r1itnhkeindgowcautmeernttoswhoorukeldrsa.ckCnoonwtrleadrgyetothtahte3sMtatheamseanhteoandy `pptaprakaoggeceeen1s13ss3,te,obpbfosotittttollneepddsrwowatvtaieadtareelribieslsoaututsitlsmeeenedddnfg&fotorri"sndy&rksiiitnnnegkkmiwinnfagogrwtewawrtaatteotererwuaaonnsrddekcdecomooionlkicCinongoog,nk,itaranmnngdd,yttshthooeepttphhlaleatatnsnthttaeiitksesimiitnnetctnhhhteeeonn `need not rely on bottled wale: process of installing a ueatment need not rely on bottled water.. system for water used in cooking, so that the kitchen = `SSpiiommtielinlatariralllyy,,o n33gMMoiwwnigilldlliccsoocnntitiimnnguueeesttofo rttaoakmkeetshstteeeppfassc itolo i tiiydd,eennntdtiif~yreaaqnauddesaatsss aatpphpptrrootpphrreiiaadttoeecrrueemddeuuncctee any any paaCcocaktkrennbnoootwwniallsleeyoddsnggigeeeomttihhnraagtetf3d3eiMMrsecnhiicssaeraadgolherenseaapdfdrayyogmaaeccttt1hiiv3veeeillfyaycfeeiunnlliggtyyaa,ggi~neesiddntdaiilnnrleessqduu,uccnehhostteesffmffteboh~rratte~st.l..tyhTTeihhdneeotchGGuerrmaapnnreutonflcltaae~rssAAcoctftiibvveaaittneegdd installed, and has shown good removal efficiency (>99%). Carbon system referenced on page 1.3 is fully installed, not installed, and has shovaa good removal efficiency (~99%).. me~ely in the process of being = AlAosscatttooiotthnhsee,ff3ooMumrttshhurrpeepcocoromtmsmmesneindchadtaaitioronen,c,ottomgmgaeatnthdheaerrtiiinnoffnoorrimmnatathtieicoonnonrr'eotggemaxddoitfinnggthooeffpff-hssiaittseeedwwaiasnstvteeestddiiigssapptooissoaanl.l AlaAoptcpreaervtvoiioiaeencwwsh, woo3iffMl33lMMas'ud'spspdffoiisllreetsssowwns-iuistctihhhterraeme~sespedpecicoeatmcatt0omnooefnffftd:shsaieittntioeeofnddiiisssnippttoohesseaamlcleoiidssniataeallxrrweteiaaotddfhyycthuuoennnddfpeeihrrrawwmsaeeadydypianTtYvhhehwesetaippyghhsaaat.issoeendd.. approach will address on-site media and then off-site media with confirmed pathways IIinnnfssouurmmm,a,t33iMoMnb,brironousutggihghtattttehhdeeaflplupurooorrpoorccihhaetememisictcacalpls,iissassunuedesspttroooMMpoPPsCeCAdA'a'snsdaattittneeinnttitiiaootnne,d, hfhaaxssthpperrroovviniidvdeeesddtieegxxattteieonnnss.iivvee3M. will continue to work actively with information, instigated appropriate will continue to work actively with MPCA and the Health Depaitment. steps, and proposed and initiated fixtther MPCA and the Health Department investigation. 3M CCOMOMMENTMSOOEN~TTNHHEETTTEESXXTT Summary SummaL~ regardinAAgpptaahrlett fsfiiopomemctthhieeossfeeficctcoohsnneccdeeormncssumwweiintthth,tthhweererheppoiowritetc'swscicohlonlcnlcauldusdsirioeonsnsss,,nwwdeeethhaaaivvleebeaalnnowmu.mnbbeTc~rooosfufmccomonancrceeirrznness our key specific comments: regalcling the specifics of the our key specific comments: document, which we will address in detail below.. ~7o summarize + Ts"uThhceehaddrslaaffstf osshhfoouuellddrrreteeffonrr"aachiinneigffsrhroomlmevsseppleescc"uullaRatteiifooennsooernrcfferrootmomvavaiaggduuieesqpqueaurlsaiiltiotanattmiivovedeecclhhiaanrIagacctftaocrrliiazznaattiioonnss enrsetuneictfihereelarlysyedinidetcfifffoeefereregrenrenconteutcsnchdhtewoemami"thceiciargalhml iiilsgservssappeteleicscou.u"lnlaaatPttii.vveaefe,ef,raicasnecii-ettummtaoaaiyyanirnsnioiodntttigsbbpeeeinraasppMipopilnlciichcmaiabbgloelade.ne.lmiSSnaigiymmfiionllioaa'trlalyynb,e,: rpeefretriennenctettoo hgyldoruongdewolaotgeilcmciognrdaititoinonast aat fhiree-rtralioncaintigonssi.te iRneM feircehnicgeantompoatyenntoitalbe pertinent to hydrogeologic conditions at other locations. Refelence to potential t~"h33eMMHehhaaalsstphrp-eleBvvaisiooeuudsslVlyaylppureroos.vviiddeedd tthhce Department Department of of Health Health with with input input regain regarding the the sonservatim conservatism inberent inherent in in the Health-Based Values.. 22000099..00007700 AMMurrg.u.JJsaatmm2ee0ss, KK2e0ell0ll4yy Page of 22 August 20, 2004 Page 4 of 22 exposure to childzen is also speculative, puticulaly absent evidence ofany. ceoxmppolsmet'eedtoexcphoilscukr'eenpisatahlswoaysspeculative, pmticularly absent evidence of any completed exposuse pathways. 8TI6tt5ww-oaoucutlledd sbbieet euussaeerffeuulrlettlooe vccallaanrtriiftfyoy tfthhlaauttornnoooctthaaellmllioocffatlthhsee aaWrreeeaasssddueegssgccerrsiitbbeseddomiinne connection wi the csopencniefcitciocnhawngitehsthine t8thh6ee5dd-aeesesctcerliisppitttieioonmn 'ooeffrcecleesivtaatinnt aatorreefaalssuooofrftothchheeessimittieeeaaalnnsdd ooWff'iseitteesugggeegooellsootggsyyome specific changes in + S`eScvpeievdreearmalilorrleeoccgeeinncttrdreaevtviaieewownss PppFrrooOvvSiiddaeesnsudumPmmFmaOraAix.eiessWo0effeesnnuvvgiairrcoosnntmmetnheetnsatelar,l,etvtooixxeiiwccosolloobggeiicrceaafnredtrdleionorcred epidemiologic data on PFOS and P]3OA We suggest these reviews be referenced + MMfioootrmeetrrheeecceeinnntftooorrrmdadetetitaaoiinlleecdditiienndifbio~srmmaavaattiiioaobnnleoo.nn tthIhnee ahhdadali~tl:itoiefne,ootffhePPFFdeOOsSScriiinpntaainnoiinmmoaafllssthttehhaactthrddoiifnfffieecrrss fSitoumdietshecoinnffuosrmesatPioFnOScitaenddiPs FavOaAiladbaltez. In addition, the descTiption of the chronic studies confuses PI~OS and PI~OA data. + TP"ThFheeOdScrhaiafnftflrrieegpphtooorrtftssrppeecececunultalalttyeessputtbhhlaaittsMMhieindnnndoeastsoaottiaanmmTaahyyibllooowdweee~sautit,sscHHteeaalalltt(hh20BB0aa3ss)eeddanVVdaalLluuaee,ss fofotorrol P(S(22uI0~0i0On03g3S)e.).nintWWlhieegeahlrrteteovhv-fiiembewawcseetthndhaatltIteyvnneepelwsuwtdbdhaliaatsthnaaetadnhndeddaceetuaxxrpprilnelaaniIitnnhMiiwwbnhohnydyeesiiattousstxhha,oocuuealtllddcaulnnl.ooa(ttt2i0rroee0nss.3uu)llttaininndmmLooarruee, et al. stringent health-based levels than the current Minnesota calculation. * ]Tt?hhheeedrraeetffaeerirenenntccheee ttcooitaaedppoossstssuiidbbylleeeafnedfffoeetcchtteoornnpeeersstto~iaanddeiniootllsiitnnudwwiooersrkkteehrrasstiiwsseuurnneffonoouutnnddcieetdde.d,WWaenedirexevpviileeawwin wwtrhhehefyyedwrwaeetneacebibneetllotiihepeevrvoeecsitttthehaedetesssttctauaatdteneymcmeaeennnitdtntiiosshtehiinneGaarippplpplerroixopltprianinraiedatnatete..dstuMSSdiaiimmenisdlileatahrlrlalyytm,o,wrwweteareeleeinxxtopypltlsaactiiiunntedwwdy,hhiyasynnttdehhteeexplain Sraaeuppfppperprroooeprpnrtrciieaaatntteeoauuspnsn~loloeecsisstassattaaieccoccncaooonmmfcppeaParnnFiiniOeetddAhbebwyyiGtaihlfpflliurallaiollnseedtxxapapelnlcaadnanaMnattciiaoeonnrndtemtholharmattassoluulitbbtassyleeitqqyuuesentnuttdddyaatitsaadndoootnnoott support an association of P]~OA with prostate cancer' moI~ality. = W WPEeeOppSrraoonvviidddPeeFe~OfeeAfer.rseancTcehesse ffdooirrfuufppededanatcteeeddiiinnnmffoeorarmmnasatetiiroonunmoolnne vggeeennleesrrba'aelltppwooeppeuunlltaathtiieoonngessneee~rruuamml levels levels of of Ppp1ooFpapOubulSolauatatttiinoodwnnoPaaoInn~rddOdeAwwro.osrroTkkfeehrrem'ssdeeainnffgggeaa~ggneeenddieefiitnoninreeuimPittFhdheeeOarrenSPP~EFaeOOnrSduStmho~ixlicePevPoIeF~lrsOOmAbAoerfftwleluueoooerrsnodocecthrhheseeommgifieccmnaaalelgrppanrrliootdduuudccetdioofnonr iPsFaObAo,utntowtoonoerodredrseroofmfamgangitnuidteufodsres' PiPnOdiScaatnedd tihntetheeedrramftorreepoorrdters ofmagnitude fox PFOA, not one order of magnitude as indicated in the draft ~epo~t. = eITxhhpeeodsdruiaarffetl trroeeppbooerrottccchiittmeeassr"'kmmalaer~vg~eilnnsssoforffo'emexxtpphooessduuetrveee""l--o-pccmooemmnptpaaalrxilsnntggudhhyuoummfaaPnnFggOeennAeerriaanllrppaoosppu--ullatathtiiaootnn `"eaewrxxeoppotltaaaskiktnueenewn htfforyrobomtmehneaacppchrirmeteleladiirmmmkiailnrnegaavirrenyylssd&orfaifa'fofttmeExEPptPhoAAesduddzoeoecvcueaurmlmocepesnmnitmtepntthlhtyaatltihhsntaacussodrssyriiennoccctfeePibbnFeeOfeeinnAghrrtieenovvfiirssateehtddse...-u-WW ntiheqeaute" `peppxhuhbapal~lraimmsianhacecwodokhkiryiinnsetekthtieaiccssscsieaatesffdffseemmccettniaintrnggfgiottnrhhseePoFeefxxOeccAxrrepetto(iisBoomunnto'eeofnfabPProefFFfsOO,iAmAetpiilannly. ffie2nem0mc0aoa4lrl)ree,errctaatthtssie.n. aluiIItgnnhhoththreosefrrrteeehpcceoceranutttnlliyyque pmnpuoaassbrtglginisisnnhtsseadoolffre'ifeesfxxkeppcaootsssssuu--errseesamffooserurbnttsthhteefaon99rt55iPta~FlppOmeeArracce(eBnarituoilltgeeefnggshieaeonfnfeenefrt,rayaelltppaool.p.pu2ul0laa0tt4iioo),nntheexxeppaoousstuuhrroeersoofrfe22p11o00~00t for for' post-nztal effects -- a substantial ma~gin of safety. `We elaborate on ese and other comments below. We elaborate on these and other comments below. 22000099..00007711 | MAMru.rg.uJJsaatmm2ee0ss,KK2e0ell0ll4yy Pagesol22 August 20, 2004 Page 5 oi22 DDisicusssioncooffuSSppeescciiffisicc CCioommmomenennttss CChheemmicicaalTTeerrmmininoollooggyy PFOA aITnhhdeePcdFrrOaaSfft.ccooWnnhssuiullltteaattsiiouocnnhrreaeppnooarzbttbrireefetev~rirsastttiooon""PsFsPCemss"FttlooeoCengncceoosmmiptpa"casossuslfdllducooarroosccehhecemomnificcuaasllissonss,uuccahh aatsshe t{PtehFeramtOmlAppneeacrfnffaldluufoPourFnroOcoetchSiheo.emnmaWiilcahaelilnslsdeaasgllusrsocoohueepnna)ccnotoahmmabptpbavarsesesvseeisassotippmoeeenrrtftislluemueooemrfsiinsncaaaltltoelegdedidcnian"elep,t~eistrsfc((voffouuulrlllldoyyccafTalnuuuboosorerininnsea"oattnaeefnddiadccsiaaaorrbnbbb,oroaeunsvccithhahataeieinndss fatahsosartPPmIelFaCrCcslks.y.apTTrfhuohindisscutiicisosenasnnaaletententhntiedirlCeegollryytoddsuiipgff)fefeetGhrrreannotttvaeccteaattfseocoggimolotrreyyyt.ioomffcAehccsehccemoamrildclieicadnalgls'sl~ypff,ieiorwomfmleuttoshhrueeogcpgpaeeezs~sbtffolurunceosrf"reooaraarellinkdycylealabasccbiiiImddepssvliyated "florochemicals" formerly produced "fluorochemieals" athe at the rather' than use of the Cottage Grove than use of the PEC aczonym throughout f~tcility. Accordingly, we PFC acaonym throughout the document suggest reference the document. simply to CChhaarraacctteerriizzaatiioonnss level wIIintnhaaonuutummabpbeperIrooopffippsllatcceceossntttehhxroto.uuggh(hooSuucttt,.thh.ee,ddoopccauugmmeenentrt,,eftthehereittnexgxttto rfehefiergrshs t0eove""lhHiiggihhn""goor~rou""ssniidggwnnaiitffeiicrcaa,nntt"" { pTnprleeeaaavlacggaeteeetlivcsv11epwe22ltlyiyarrtebhehhfloiefiygugrerhhthirnailliepggevnhpvteogerollolses.hphv.))iiregiglahhsITthehilleeeecvssvioeeeennallatsaseprrxpnarertne.dor.dlepalr(ssatiSiitgaigeitvvnneeieei,ffieiittc.ecgeara.tm.mnnh,titspslslyaycgiIoTTmemnhhtpe3peeaiiaxrrscce'tttfiieememddrWpproggieonrrrrtogotsiuuiutsnnogddgtuhwmewnaiscgcattllhteeeehrasrI;e;re,,vppdaaeaaonlnggscddeeuinaam11nn'e4*gyynr~rotsseeuuufrfnggeengdrgfieirweisannsatigtgntiieoto0orfnn;ioooffm Vague or speculative qualitative chracerizations unacceptably high levels is inappropriate in this context vague or speculative qualitative characterizations We suggest the document refrain f%om ischargSSeiismmifliliaarorllmyy,h, ttehheoEddaoogccluuemmPeenontttssuuwggaggseetssettsswatththeeerreeucmmaaatyymbebneetaapnnlaissnss,uueebuwwtiiptthrhorrveeigdgaearsdntooo ffflouuuconrrdooaccthhieeormnmioiceraalltis comment dischaxges comment. fi'om the Eagles Point wastewate, treatment plant, but provides no foundation fo~ this "could h"TTahhveeeddobocecueumnmeenextnptoaasllesdoo iinnccPllFuudCdeesssfwwohhamatstiaarppeppmeeiaasrrsssittooonbbseewahibblioelielPestFpplClaatpteerossdeeucccttitioiononnssuuwggaggseesosttciicnnuggrcichnhigill,&diaeennnd c"caocoduoudluleddlddc)chooannIvtitiennfguubreeeteh0tonerbbesexeupegeogxxseppesodotsssteoed"fPttcooFlsCsoiosililldfiecc'oonomnnmttaaaamimyriienlnmaaottieesddsbioffrncoosxmmpwothhsheieeldeddeoPeppFoPoCssiEipttCiirooonndfuooocffmtiPPoFtEnCCewss.s.aisteotc"chuo((_EuEtrgmminhppghh,aaassniidss ccaoodnndtteaadmm.)iinnaaIttteefdudrstshuuerr{rfaasccueegwwgateasetetrsrss"o[orcz]hsseeidldidmirmeentnesn.mt.s.ay...a..l. so" be((EEemmxppphohasasesidisstoaaddPddFeeCdd s)) fIiIoffmeexxtpphooessusuirrteee tphartohuwgahys pathways aarree {idhetnttihfeirede,stchesyuwcihllcobmepelveatleudateexdpoasnudresepastshweadysa,sssuppcrosppreicsutleatiHoonwseevrevres, naobspeunrtpossoem,ewidndication identified, they will be evaluated and addressed as approp6ate However, absent some indication tShhaotutlhdebree adreelestuecdhfcoommptlheeteddoceuxtpioesnm: e pathways, such speculation serves no propose, and should be deleted flora the document. Site Site DDeessccrriippttiioonn Grove, MITihhneene33sMoMtaCC.oottttGaaeggneeerCGaralol'oyvr,eeoFFnaalciyilltitthyyeoosccoccuuuplpiheiaesssatapeppnprropooxxritimmiaoatnteeollfyyt88hi66s55paarccorepessetooyffphprrsooppbeeerrettyny iuinniClCzooetttdaaggfeeor mCmcar_aanenouavuftefs,iacMoehtnmiwnsininnnedggsofaataannr.dd.middGneegevv,neeelolorroapphlmmlayese,nnrottenoomlfyaf iS3tnhMMeedpspaorlsoouddnthuauceteutatrsssatelTTlhnhhabpeeiortrreaettmimoaaniinnoiitnntgghippsoorplttriiooopnnerhhtaayss beer ued fo: has been utilized been used for recreation and farming, oi has Iemained as natural habitat.. 22000099..00007722 MMAiurr.'g,, ualsamtme2es0s ,KK2eel0lll0yy PagoGof32 August 20, 2004- Page 6 of 22 toinvestAAisgsattthheeeaddnrrdaaffattdaadccrkkennsooswwvlaleerddigogeuesss,,a33reMMasahhaasstbhbeeeeesnnictcaoeooppeMerorraaettionnvggewwri,tithh3MtthheheaM MsPPcoCCoAAperssiianntcceeedwaatit tlleehaatsshtte11998555 tSSeottaaaittnteevsdseieisnantcilcgeeoattfthehieeannf11od99r66am00dasstdtoizooensppseeirsvrammaviriatitoiaaulnnsbddlaraeaeddarddselrgeaeastrsstdhotienthhgeseirvtreaeer2nnivvoiuMirrsooornnrememaoesevnnetotraaf'l,l t3aahMccettiishvviaititestieecssoaaottpthehreeatsseiidtee.wTiTthhhusths,,eaa great deal of'information is available regarding various areas of the site. lovantMMtuouccMhhorooofftcthhheeemddiiisscccauulsssssii(ooenno3.offtathhreeesaarreeclaaasstaaedddddtrroeessassneeddaucurnnydldeiecrrtathcheiedssriiettelserracesmme)eeddiiWaahttiiioolnneaawcctetiivvaiipttpiieiecssiaaarrt'eec.nnoott rti{henhelveeeDDvseatepinpgatmarttottimmofenlenuantovt'ri'osslcaddhbeeelssmefi,irieeitattoolwsoiin(nueccl.llgduu.d,dbeemesseuooasmmesfeeruelbblaaattcocekkdcggltrarooroiuuafnnnyddtahddcaeretsyscolcrirrciilppayttsciivivodeemiiieennlfefooaofrsrmetmh)aaettiiaW oornnehaggisilievvdeeewnsnecttrhhaieepbepeedlxxeeticerninattttheooeff idrvnolalvaaffetlsitccliooegnnaosstruiugollatntnaaitatiicvooacnnioltrameebppploooert,u~tintrrdewselao(atue"lttdoVobOfleloUCurOssoelcOfauhtCelthmtheoiemccsialcialaerlsiswf~hMitMhcooahrrtcehoooanvvveleeyri,,bsaoeasmenttehhteoohfeddtoofhccoecuuummasreeenonaftstaiidnnerddseiicccaraatittbeedesse,d,attliohnheefthtehe investigative and remedial activitefos volatile oxganic eompounds ("VOCs') investigative and remedial activities to daiedo not pose at the site which date do not pose a human health concern have been the focus era a human health concern great deal of the GGeeoollooggyy is unfounTIhdheeedc.coommTmhmeeenndtotlooonnmipptaaeggeei6s6dttehhsaacttrithhbeeerdreesamebeiaanbbugunnuddpaalnnft[essdoo,luuwttiiootnnh cocanavlviytitiieiescs iilnnottwhheeerddpooollsootmmoiintteeseggmeeaooillonoiggnyyg bbifeseenaunetneuafratoethsuh.tnfdhilTeeehdsus..iistt,eeT,,thaahennedddptorthholobeeamllboiiotwlweieetirsryoppdsooeorIslttciiurooitnbnieiiosds naaaccsfkkebnanetooiuwnwrlgelseeuddbpggeleeinfddcteattdtooh,bbwteehiemtmhasasoissntsiilvviyese,t,lhowwewi.ilttohhwffeerewpssooorltliuuottniioornnemaining features.. ]Thus, the probability of solution featmes beneath the site is low.. depressi"ToThnh,ee affanaudulttthlliuinnsees~rheeoffueelrrdeennhccaeevddeoolnntpplaaggceeff66ecsitsoaanttttthhheeepooeuurtteferor reemddaggenecooefftothhfeecthcoonnseietsoofpfrggorrdoouuucnntddiwwoanattweeetrlls ``dWmWeieepnhriheamasvavselieoicncnoo,fnnalfnfuiiedlrnmtcmheeeuddosnwwsihtitthohheuttclhdhoeenhaaeauuovttfehhdoolerirtptoolrefeftstehhsfefeieorrcenetppooonrWrttethccieitttehpedederrooefnnofroppmraaagsgnueegc66geettoshhtfaattrhtetehhveissiffitaaenuuglpltt~thsosehhdoouduuiclstliddcounhhsaaswviveoeelnl~o.n pages minimal page 6. influenee on the eerie of depression We therefore suggest revising the discussion on for manuSSfiiaxxchthiuiggrhhi--nccgaapopapacecirittayytpipuoumnmpapiinntghgewwseetll.lss ((Iiinnnssgtteaanllellreeaddl,dduurriinngpguttmhhepippneegrriiooofddg11r99o44u77ndt0owa11t99e77r00)0) 1ssuuoppnppll-yyswwiaattteeerr pulfJooomIccpaamlilllaynyngaauwllftteaeelcrlsstlmttshhieaenntgnotorohltepthheC-rottatoott-i-osasnooguseuttGahhtrirtoehevggeeiiosoifnntaeaac.l.illffiIllntoyowgweAddnliiertnreheaclcot,tuiotoghnnhebbhpyiyustiminonrpddiiuucnccagilinnwoggaftiignenr:wwoaualrernddvdewgglrraaaatdtdeiiareenfnibttnIssdiottocnoaww-tsaeairstreddautthsheee pnRCaruatetmuuartrpaaeildlnhhgayywcddoreenalaleusoilifacct gdgthrelaapeddrCieieesonnstttitaottgonoewwiaGnmrtrddhoevtthhegeerfoiaiivcuveinelrdiI,t,ywpp.auutAmmeplptihbinnoeggnuegooahftfthhthhitesehtdowwereeivcllelassll((wowhpahtieeic~dchhlpessovtraaettrliteoednddastiiaonnfin11td99h4i4ec77as))itethh.saassaThe created a cone of depression in the ground water beneath the developed pmfions of' the tchoeneaodjfadceepnrtersisveiro,n effectively limits movement of ground wate fom these developed cone of depression effectively limits movement of gromad watei ftom these developed areas site. areas toThe to the adjacent fiver. 'oboonnOOrmisniinteMMgesavuaywyktiela33izs00ee,,ddi11fn9t9soi8t~8r5a5tml,r,lene33redflM1ltyyoaaffonnoovrddrawlwMMaaaPssPsttCtCseeAAtddhiieeesspnspeoitosetsrarlae.dlnd. dniBBntfeteooottwwvaaeeeCCreeoinnofnnys11se9t9enh88net77t MeOaarinnPddddCee22rrA000t00oa33p,ii,nnpmnvvrueeeosmstrvtiieeoggraaourttueeesssaapmmnnoodndonsnirreeitetmoamoererediiodnininaggatstwweeewellleloollrcsteanaitinododnnssssooiill baCe5foifreediccnoticgiveuse.m.w.eenAArileleLlidtnreeisnsstapptloohlennedssMeetPoaaCccettAviio'aonlnsussaSretieetqetquhlSeluuesdmitbmebyayarnttyhdheeWtoMMevPbPeCCtPiAIAa~giietnnh(etthhMeee CPC/oConanAsseeannpttpOCrporerdvdeeserdrawwiteeeesrmrpeeonsnsaastetisspafarcacotcitgtooornrrasillmyywseccprooemumbpelepttepsd 200150g,e 48 as documented in the 2001.pdf), page 48. MPCA's Site Sumrnaty Web Page (http://www.pea.state.mn.us/prog~arns/pubs/plp- 22000099..00007733 Mi James Kelly Mr'. James Kelly AAuugguusstt 2200,, 22000044 Page 0f22 Page 7 of 22 DDisisppoossaallAArreeaass LatetheTTdhhoeedcdouocmcueumnmetennctt(ap(palaggesescs h33,,t55h) erreeffdeeirrssspot0osaddliislspopcooasstaaillonooff(' fuAlroueora~c3DecIhh)eemmiiicbcelallssieiivnneaadnn oonnh--assivitteeeb""eddeunummappl.TM"nc vvLHaaauazluttealt,rr,datahonneuddsdttowhhaceesuatmmee.aretineMtaricPlallCasrpAiplfliaaeaccspeeptddhroaiitvnnetithdtwewtedehrirsoecpslosoesseamulrimlesooaclianidtdisaotmansros(atAthhl~anaettawiwaDeedrIrg)eoinnsefetbueiertxlsuiaeldvtiizesedrpdoataosananhllddawiivwecee.rzbreeeenTenhondoittsa lined hShaozualtddobuescwlaarsitfei.edMinPtChAe saupmpmroavreydstsheweclllo,saunredatnhd tmearnma"gdeummepn"t avoided of'this disposal site. ibis should be claxified in the summary as well, and the te~m "dump" avoided. characteInrniazaetdd.idiotiBnoon,t,htthrheeeaddsoocchuuammveeennbtterfeenfreprsrsettvoiobbuotstlhhyDDdIIeaacnndddDDs22pparrroeepaarsica8tsennloyotchhlaoasvveiidnnggbbybeeMeePnnCffuAull,llyyand a cha~acteIized. Both areas have been previously deemed appropriately closed by {ShoeurscaetitsfeaactgironooufnMdwPaCieAinvestigation for PFOA snd PFOS has ben completed source area groundwater' investigation for PI~OA and PI:OS has been completed in the DI rez MPCA, and a in the D1 area (0 to the satisfaction of MPCA.. mistcadiTInhhgeedwdiootchcuuomumetennattlooonnpoppiaanggteein8gssottuaatttehesaththaatht eAAr~aceraaaDDwS5assshhgooiwwveeeddn sllolowowsllueeevveebllyss ooMffPVVCOOACCssw.itTThhhtiihsseiiss : Seknowledgement that he VOCswereappropriately manages misleading without also pointing out that the area was given closure acknowledgement that the VOCs were appropriately managed.. by MPCA with the still isaPPpaaoggemei88tsseaadyywssaAAsrtreeeaa dDDi6s6po""swwaaalssocoennacc,eeaaalnnt haaoccuttgiivvheen,, oMMwPPCiCAnAa-cp-tpeievrmemaiittteedd west waste disposal disposal area area .... " It It still is a permitted waste disposal area, although now inactive of h iW Wsiaittrhherraee1ggaarrddnttoso cAArrraeaat eDDS8t,,o istuigs aiimcmtppotoritrats'nawttattsoo nsnioomttep lttyhhaaatt rccoounnsmsttrrduuiccsttpiiooosnnalddeeabbrrreiiass was was alo also disposed disposed of' in this area; it is inaccurate to suggest this was simply a dzum disposal a~ea. htahceecco~maapttalIInnnrrieeddeppiidososrccrbtutuyssnnssooiiitnntnefgegsottrtthhhmheaaatttccitthhhoheeneemmitppicrrctaeealvvltiissooheeuuewvsseeessrsreeewllwiienennrereossppdiiiinpanpteettasshhesehhuaaufgdldogurebobsoeretoceincnhnhegllemeaemaiankckiyciiananlpglgo.PPterrTTnoohthddiiiuusaslcctstiitiaaoomitnnpeeammAAceretrncenttaatossoohhnnooppuualalgddgeebbeo99,, agcrcoounmdpwaantieerd by information that there a~e no data suggesting any potential impact to groundwater.. Fire TrainingArea Fire Tiaining Area urusscee ooiffntthtLLhheeaaennffEiggoruueReaaGtaggraneeWiinoooinnnrngkgppaarpaggcrleeeaaa.n11.44(T2Tmmh0ha0eae4ydyd)eggesrisicevvcrfeereiirptptshthtieietooosanndppuooppfafeelaetse~utasaisntnicnsnceggeoofoootffff'hcfcfuosoin'enrertarssmaduuadiptpcipepcirrteoeiosasrrslsyyasaniinantnssffoioaarrttsmmtfahaltcetoiicoorrannuteiertoentiog.rganaidrinTdiinhinnneggggirs STasuureeppaappmrrieenssastsnhaadetaatftEssoRrwwGmeerrWeeeuuosrsekededpftltbaotnrrrbbq(oo2iutt0ihh0tffe4niim)rreextnegtafrteias~innsieitnsnotggadbeeulxxaeierlsrchuciesisdseeebssyoffofothtrhettehhNseeeaffm~avtccatiyiotlleii.trtcyiyaaEEltsmmteayetrrtgtgheheiensncpcloryycoMMadtuaiaconntnaa.g.ge3eTmmMheeenntftire Tforepoececaerimaivvteeiaddonndppsaeefrrommritmihssesseiiefooitnrinneaagtnnztneiausnltaillrnleygyqwffuleiioroaremamttehhnetssstaeaestet,a,bcsltaiasrlhtiienndggbiiynn ttthhheee Nllaaatteve y1199to6600c5se,,rtt1oi0fyccoothnndeduupccrtot dtthhueecsst.ee 3M operatio~as at the ~'e training area. migratioITnhheeatddaiissmccuiusslsseiiooynn ooffrf'teth-hveeaMMinooioondgdyyaeeettsaalil..n. ppMaaippceehrriregegaganacr(ldpiianngggegsgrr1oo6uu-nn1dd7wvoaafttetrrh'occdooinnattalatmmriennpaoatrtitio)onnshaaonnvddld not comparable. The cport should be cles that the migration observed i that study was under migration at a military fire-training area bbee ggeenneerraalliizzeedd ttoo tthhee CCoottttaaggee GGrroovvee ssiittee maabbsMseennicttheeivvgiiaddneen(npccaeegttehhsaatt1hh6yy-1dd7rsoooggefeotohlleooggdii~ccafaatnnrddepooott~hhete)rr schoonduiltdinonost. conditions tahree ccoonmdiptaisoanbsleo.ftThhaet rpeaptoc~atlsahsoustlde.be cleas that the migration observed in that study w~ under' the conditions of that particular site. 22000099..00007744 AMMau.rg..u.JIsaatrmn2ee0ss,KK2e0ell0ll4yy APauggeussto2l02, 22004 Page 8 oI 22 AAiirr'MMododeleliinngg cited beW"chaiu-hlsieleeiwwee1saaappvpapirrelcacbiilaaette, wtthhoaatbttlthheevaaeiisr dtdhiisesppdeeorlssciiuoomnnemmnotoddseheloliiunnlggdrrceealluaattteiedodnttoothhhayytdcHrhIooggheeannsffvluueoorryliidddeeif((fHHreFFn))tiiss pphchihetyyescdsiiaccbiaaesllcsaaaiunnosdndesccishhtoeeiummsriaciccveaasallialppanrrbdoolppece,erolwtntiiceeeessbnefftil'aoioetmmvieoPPnt]Fh~OdeOiSSdf,f,ovcPPeu1dF3m_OOeAAAnctaacsnnohddrodrruielenldagatlcedyad,utaatinnoadden pfltlrhuueaoodtriroIoc-cItcYhehedhermaHnsiFiccvaadellirs,ys,paadennrifdsdfiethorhnaeatntt mthaeyeanotitssbieoncsonscouurtrceenstmwiidthcolnucoetnatcrhateimoincsadlifdfeep~oesdi.tiAonccordingly, the pledictcd Ht~ dispersion may not be concurrent with fluoroehemical deposition wereperAAmttitttheeedttoopp ofpage of page 15, 15, ples please clasiy clmif~, th the last last ine line fo to state state thatthe that the tacks stacks mentions mentioned there there were pelmitted `Well Testing Well Testin~ {be fu nI1nondatdidwtisititoonnpotorotttihhoeen ppoirfivv3aaMtt'eeswwpeerllollpsestrettsyteedfdorbbyySuMMorDDoHcHh,,em33iMVcahlhsaa.ss aalNlsooo etfeussotedodchaanenmririircgigaaalttiicooonnmwwpeoellulnoodnns wtheeefadt entoercthewd est portion of 3M's property for fluo~ochemicals No fluotochemieal compounds were detected. 14,15, In1n8tthahenedttaa1bb9ll,eeraaettsptthehceetttioovpeplooyffsppuaaegg5ee0,11111d8ed6se,cs9rc1iribbaiinnngdgo6on2-ns-eissitttee mmoTonhnietitmooirrsiinsngignwwgeeollxsls,c,otthrhreecddteeeppdtthhussniooqffu'MMe wW Well wun1eui4lmm,lb1bn5e,rar'sms1b8aaettareen44da22r11e19771,001r552e,,sfp34ee31tc12t2i3av3n7e7d,l,yS55Ta77~000e3336222033,, saaInn8pdde6c,66t911i122v77ae11nl33dy 6MM2FoWfWre-et-1t1h77~pii[sashoeromammigtiiatsttpseeihddnagbaenon~deactthhtoeehrrddteeehcepptettshdhbauainnnddiqouununnepiiqwaqugueeeell w1,ellPnWumTbieIumse 1o1c2cfaeseitoannadl5t7t0h32e23, rMesopne-csititvcelyap 1a3nogi eth,eapnad~aPgWr-apShsbuepnpeliaeths tthhee gtaubalredosnhapcak.ge 11, PW-7 is used occasionally at the 3M on-site t~ap ~ange, and PW-8 supplies the guasd shack. the ilyIInn.tthhee ffoouurrtthh ppaarraaggrraapphh oonn ppaaggee 1122,,PBWW--44iis inthe in the notes, northwest, nt not the the northeast northeast orion portion of of the facili .ty. availblITebhwiiesslpplaasrt'taaoggrcraahpaprhhacrretceeroimzcemuoeonrdmoscamahcecoemooiodrcnidanildnaatltseeevddisTo.ouunn3ddMoofafgggrrreooeusun,nddawwnaadtteel~arstssaaymmeapprlliisnnuggbm~frirotonemaadallal oWofofttrhhkee PiPaaavllatnancilaattdoobyluueonfwfdneeerlreldtsadktseoeusccsuruhhccahahtrsapascraamtoempprlokpizislienanelggf.l.u. oW Wroeeerhreeeqmquuieeessatl htthe levels.. that the document acknowthlated3M ghaes 3M agn'ees, and last year submitted a document acknowledge that 3M has Work aheady offe,ed such a proposal goundwPPaaagtgeeessm77odaaennlddi11n33giniandrdieciucaanttkeenttohhwaant.tthheeWsshoouuirrccteehoeofygmtthhaeeymmohodadevelel bnaondcdaaaussssnuukmmnppottwiioonnnss uutnnhddeceDlrelyypiiannrggtmtthheeent of HHDgereaoealultntphhd,,wttthahtattetriiinmfnffhoooardrtmemalwaitnotiiugoolnnadlhhbeaaoussbnbhekeeneleopnnwfpupnrlr.oo.vviWiddeheddilettoothMMePyPCCmAAayaahnnaddvcceaabnnebbeeen made availabe o he unknown to the Department made available to the of Department if'that would be helpfial iiinnnttveeerrsmmtiiitgt"~ttaIeethhnnieetotnssssuuteirggrepggeaeoaemsmstttiiiiosfsoonnuurnnttthffhhooeaauutttnnggmddrreeeooadduu...nn.ddTGGwwhrareaotortueeuenrrndiffdwiiw'aonotmoamete~rttvhhiffeeldloDDeow1n1wciieaannrrtteethhaahaeotmmDDfaa11oyywaaddririmesscoacchvhwwaaearrasgsgseeftartoonioagmnttuhghtleeueal~iatviDtveeeIcdsdr aivivnniviaeetthhttheehteeoward itnhveeisnttiegramtiiottnenretpsoeItafmor that mea Yhe~e is no evidence that flow moves flora the D1 area toward the intermittent sueam. 3M agrePPeaadggoeto11c44,o,miinpnlttehhteeeddaiissdccduuissossniioaonnl oomffonPPiW Wt-o-5r5inaagnnddofPPWWM-u-o66t,,osschhhooeuunlilddcaiinlncscllunidtdeehrereefsfeecrreaenncceBea1tso0ettdhheeonff~apetrtettvhhiaaottus ~ns3eeMpseopdanogbnserseeeceaaodccmtttpoiiolocennotssmeaadftptlthehteee D8 area related fo VOC's, MPCA aged additional monitoring of fluorocherrficals D8 a~ea related to VOC's, MPCA agreed noin no further monitoring the area Based on fia~ther monitoring for VOCs previous for VOCs need be completed. 22000099..00007755 Mi James Kelly Mr James Kelly AAuugguusstt 2200,, 22000044 Pages or22 Page 9 of 22 `CheCmisth~y~PePhyhsymisiccaaill/CChsheemmiticcaalrPPrroopyperetr,itieess chain PPPEaaCggeeco11m66poeeuxxnppldlaasii.nnss LtthohanattgePPrFROcOhSSaiccnaannlbbueeopporrcoodhduueccneeddicbbyyadoltthheenohhtyyddcloolelyyssisgs(oo0ffsrPhPOoOrSaSt1Fe~rdcaannhddeaotnthheeri long- long- OcfMlhnuualooiyrlnootoPchhFheeCcPmnOciiScocFama-lsspdoe((uerenig.dv.,,sep.dp. sesLtufloblvunstotgoaieondrdceceechscaaadinnneeegfrslsuauudollfefroootnneoaahttPeeeFmOddiSoocc.easslsnnTdoohotteddnreeoeggtfrredaareddegeenrcatoeodesppheetoorlfuflsllUhudOoobrltOetoeootrcoctctPaahnnOaeeSinFss-uuldlffeoornniaaviteec))d. cOonmlypothuendPsOaSnFd-doetrivtoeodtshuebrcstoamnpcoesunddegsr.ade to PFOS The reference should be to POSit-derived compounds and not to other compounds.. acids" PPAaasggeepe11r2f,2uaatotttt,hhoeeoceetnnaddonofefsttfhhoenssaeeoccooinsnddanffuuallcldpp,aarltaahggerIatappfhhe,r, erreneffceesrlssshttooou""lpedexbrffellutooorroooocctiaanneseuslufolnfaotnesatanendsd "perfluoooctanesulfonates wdothe acids" acids." As peffluolooetanesulfonate is an acid, "peifluotooctmlesulfonates and other' acids." the tefelenee should be to ofdata PtPoaaggsee 1u166sspaatyyhspsistthshotaaatttPPre]mF?eOOtnStS.ddiissMcchhaarloggeeddrt0othaiireervwweiiplollol riaappprviieddsllsyyuerddeeeopporfossiPittF,ttOooSssooiilsl teWWpeoeararerdee annsoott3aa3ww1aarxree o1f0d4aPtaat@o 2su0ppColtthis statement Moreovei, the rape1 pressule ofPFOS isxepo~ted as 3.31 x 10"~ Pa @ 20 C. TToxoixciocloologgicicaallIInnfioorrmmaattiioonn databasoW Woeenaafpppuproreerccoiicaathteeetmthhiaacttle~souobspptaaaggneecssesoo.ffssHuuomrwnmemavraeryryc,catannnwnoootutldddoojbjuuessthtieicclapefttuool tt0hheeceeixtxetteemnnossriiveveertteoocxxeiincctoollooggiiccaall etdreovavitPaieaebwfwaslss,ue,oiiornnnoccollfuculudtdoaiinnnrgogocaBBhtuueetmt"eeinRcnehahgoluofslffueaefbtttsotaaar,l.ny.,"cT"CeoChsx.a.hiracaHtocaoltcowetgreeyilvizz&eaartt;PiiohiotnanwroofmoRfauRicldsioslkbkoeffgohoyerl3GGp9efeua3nlc6etar3oal3lc8PPit0oeopp(mu2tlo0ai0lte4ioo)rn,necpEEerxxnoppvtoiosdsuimrneeg a rtrFoeeovvrPiieePewrRwflOauaSnno,ddromrso~oecsrktkaeaansisosnsaefetsoessr,sm"mmaeRetnneittgoouonflfiaPPstoFFavrOOayAiATl,,iobaaxlnniecddoiKlKnoee3gnnMynn'&eesdd"PyyEheenattvraiam,lr..oa,2nc20mo00el04on4g,t,yatrle3eva9vin:ie3dww6iH3inne-ga3gl8PPt0PhF(OAO2s0AAs0e(4tosx)sx,imipccerooonlltvooiggodyyirng a Perfluorooctane For PFOS, more Perfluorooctane Sulfonic Acidand ts Salts" August 20,2003 (3M, 2003) information is available in 3M's "Environmental and Health Sulfonic Acid and its Salts," August 20, 2003 (3M, 2003).. Assessment fox PFOA TTWhhheeildderraatffthccooennfsesuuclilttsaattoiiofonnPRrreeOppSoorztitnootnnpwpaoagg-eepsse44nnaendrdta2o211nssettapattressodtthuhaacttiPPvFeOOsSStudiissie""smmporrloeeduttocoxxeiicc""rtethhtaaennx PinFcOidAencWe ohfileefftheecte,fftehcetscaolfcPulFaOteSd ibnentwchom-gaernkedlaofsieosnfroat sreeprruomdulecvtievlseosftutdhieeswporocdoumcpeoaugnrdesattehrat Similar. Thus,tisstatsheoulmdbeedenletted cicnaacuuissdeeeneefcfffeeeccottfsseiifnfnerrcaatttsss, aatnnhdde mcmaoolncnkukeleayytessdaabrteoenssiicmmhiimllaaarr.l3k> dNNooos-e-eesfffffeobcicttsleleervuveemllss leinverlespeoaft't-hdeostwe ostcudoimespoaurcndalsstohat in ~epeat-dose studies a~e also similm. Thus, this statement should be deleted HalfLife io Serum Half-Life in Serum PEOA vTIahhieeeshhawalif-dlleiffleyffiiinggduuirrfeefssepprerrneetsseesnnptteeecdideoos.nn ppHaaoggweeev11e77rcc,oorhitIeeecctdtlliyyfnneoontteecetthhsaattattmhhoeeneegsstisimmpeaacttieeedds hRianlahf-elsif-hea1ooifffs POfIaPOFAOvSmaireesnwotidseolyreinatdiafsfesruegmgesspteecdies.. Howevei, the differences among species in the ha~'-life of PFOS are not so great as suggested.. ; * CCoommppaarleetthheebbeenncclhmmaaarlkkddoosseess ((ss~cuumm ccoonncecnetxnattiornas)tpprireeosseennntstee)dd ffoorr PPIF:OOSS m m 3M 3M (2003), (2003), of of 26 26 to to 92 92 pom ofvos ences fo oc bench does fox PFOAprscted in Duenhot, ct af. G004). ppm tbr various endpoilats, to the benchmmk doses for PI~OA presented in Butenhoff; et al, (2004), Tinging rom 23 prafor iverweght meses, 29 pp forpost etl elects nas 0125 fr Leydig ranging from 23 ppm for liver weigl~t incleaSes, 29 ppm fbl' post-n~tal eff~t~ in ratz, to 125 for Leydig cll tumors mats cell tumozs in xats, 22000099..00007766 AMMuerg.uJJsaatmm2ee0ss,KK2e0ell0ll4yy PAauggou1st0200f,222004 Page 10 of 22 7.5 dT"aTyhhseeindartaaaftfttsccooannnsdsuul2ltt0aa0ttiiodoannyrsseppionorrcttyreneloliemesosloognnusaannmOoOnEEkeCCyDDs.ddooTccuuhmmesennettroaonmn PePlElziOOiSSpaiintndodiniccahatitanignlagafhhaillnf'lrliiiffEse 1ooSe7ffd7.7i....5s55udddiaaabyyyusssioaiannppappraaartroseepnnatpntloldyyse2iissd0tt00aakdkeeaennyxcsffriie'onotmimeoynIJn,ooohnmndhsoolotgnhueeosttmIaalo.Fn((i1k1f99e77yo99sf4.a))C;;Tibhhmooeiwwsneeet~vviueeorm,'n, tetihhlniaamTttaoionsbbassiteesirorsvvnuaabthtsiiaotolnanfm-rrliieeafppelrrlieeynsseernnatttsss ledisttibution as opposed to excretion, and the half-life of elimination in ~ats is substamially lloonnggeerr tthhaann tthhiiss,, iinn tthhee rrangaeoofnf110g 000--11e2200 ddaayyss.4* cynomolITghhuees22m00o00n22kOeOyEEsCCiDD dadoosccuuubm-mceehnnrttocnocirocrrrseectctutldlyyycc(iiStteeeaddcaaahlealtifl-l.iffe20oo0ff2aa)ppprHrooosxwiiemmvaeatrtel,lyya22r00e0c0enddtaa,yysssiiinnngle ``cinG3totnrrtaaoaovnvmaeenno,nolgou2uss0s0ddm3oo)soseeonkuppehhnyaadsxmmsincmaocakosiokuvibneh-teaactilhiccronssfnttuieucddoyysftiiunn1d3mmy2a(adlSlaeeeyaaaecinnaddnt emfeetammlaaealis,lee2acc0yny0nn2goo)emmoHo1ll2ogg2wuu-sse1v4mm6eo)ror,naiakneerdyeyscs1e1((n0NNt,odokaskieyenrsrgliaaennndd fehGfemeemarrlemaeleiasssnn,(aor2an0nl0gagn3eeg)e88f8d8o-i-u11fn3f38de8)r).ae..nmcTTeehhaibinsesthsswttaueulfded-nyylifiaisestmmsoofoa1rrnc3ed2ccmoodommanpypkasaerriyanabsbmllieeantolcoelsttih(hnreaansstiiginneoggnll1ee2--hd2dao-o1lss4lee6ess).ttuaudndTyydhii1enn1rrh0attdssaayilTTsfhhiunuossf,, ethleirmeiniastnioonlairgheediaffterienicnethbeetawnegeeno~fats10a0n-d1m20odnekyey,sainndetlihme iAnIaFtiofn hoablfs-elirfveedTinhemhoanlkf-eliyfEs ionf meoaf1n0asnd 132 dayi,females andmalsrespectively elimination ccoommppaarraabbllee in the rat is ssiinnggllee--ddoossee in the range iinnttrraavveennoouuss of 100-120 days, pphhaatrmmaaccooklidnneettiicc asntuddtyherahnaglef-dlifferoombs8e8rvtoed1i4n6 study ranged fi'om 88 to lZt6 mdaoynskweiytshin days with a . means ofl l0 and 132 days, in females and males respectively. EEll~fctsifinn AAenniimmcaa)lStSttuuddsiieess The drat report on pages 17 and 18 refers o adverse iver effects nis The &aft report on pages 17 and 18 refers to adverse liver effects in rats + pTInnrotthdheueccceaassmeeoorotfIa'lPPiRFtyOO,SSa,,nildivvetehrrueesaffftfeeeccttosstmanaenpprareepdpdrooommpirinniaaantntetlleyynaadddpaoapipntiitvvo0e eerxxeccpeerppettseaantttddooosXseeisscktthyaatt produce mortality, `aannddaaddvveerrsseehheeaalltthh aecnffffdeecctthtssusiinnarrriiessknk oaatssassenessassmpmpeernnottp?"riate endpoint to represent toxicity *4 AApphhaar~mmacaoekoiknientetiicc s studtybbyu ytthhed essaaymmeeaauutthhoorrssddeemmonosntsrtaratteedd tthhaatt tthhee wwhhoollee--bbooddyy eelliimmiinnaattiioonn hnaallff-'lliiffee ooff PEGS im te 1 i air han 89 days following neve dose Ochs etl 1979). In that PI:OS in male tats is g~eater than 89 days following an intravenous dose (.Johnson et al., 1979b).. In that Sad, 42% of th adelwasexceed nn nd foesby day 89post ose. Based on rs study, 42% el the radiolabel was exacted in urine and t~ces by day 89 post-dose Based on this vervationto,e elimination blFifo in he ot mtb ese ha 9 days, sed is ely tobe in the observation, the elimination half-life in the rat mast be geate~ than 89 days, and is likely to be in the Tiofn100g10 120days. Evidence om scum PFOSconcenaondat iaindat fou and 14weeks ~ange of' 100 to 120 days. Evidence from serum PI:OS concentration data obtained at four and 14 week~ ina itary hon osandct anes study in ts (Scat tal 2005) also support a oags Fle in in a dietary ellchic toxicity and cancer study m mrs (Seacat et al., 2003) also support a longer half-life m 12 Tn epentdoe pamacokneic, dead ste 1 wally achedae approximately vel ves, ~ats In repeat-dose pha~macokinetics, steady state is usually reached after approximately five haK lives, nd heresies, se, concentrationswouldntbe expcied ress signify If he clinton and thereafter; settk-n concentrations would not be expected.to increase significantly If the elimination Es were 5 days, der woukd be eating laysscrum PFOS Conoenttions i 5-6 wl half-life were 7 5 days, the rats would be nearing steady-stme serum Plies concentrations in 5-6 weeks 375 dae Hoeventh cross Stacy sm contsons continu t ccs subsantally (37.5 days). I-Iowever, in the e~'onie study, serum concentrations continued to increase substantially Lehween weeks ou and 14: ines tio, meatin thatth bie i sgnifcanty onge an 7 5 between weeks four and 14 in a linem fashion, indicating that the halSlife is significantly longe~ than 7 5 daysdays. *s IThhee hheeppaattoocceelllluullaa~r hhyyppeerrttrroopphhyy oobbsseerrvveedd aattlloowweerr'ddoosseessiinn PPFl:OOSS--ccxxppoosseedd aanniimmaallss iiss aaccttuuaallllyy aann adapive sponse etthn adver fet The ypercapywas iiato mild nd was adaptive ~esponse rather than an adverse effect Ihe hype~ropky was minimal to mild, and ~ws ever omcesaton of dosing. alors with hyptophyaul ad sisal significant rever'sibIe on cessation of dosing. Male rats with hypertrophy actually had a statistically significant incense Hfsen ve cons Moxe sxous vr phologyetecain possbl net damage (0. increase m life span over controls. Mo~e serious liver pathology representing possible live~ damage (e g.., eesad hyprplse) was no ames ested ding ne 104. onic dca ly necrosis and hyperplasia) was not a t~eatment-related finding in the 104-week chronic dietary study. Tiypeplasis of ve el wa not ober in sb-cronescies with PCS, and hepateceia eciosis Hype~plasia of liver cells was not observed in sub-chronic studies with PlieS, and hepatocellular nee1 osis was obsvenldy i one ou hn sad st doves ht produced eality Serum elicl chemistry was observed only in one sub-ctuonic study at doses that produced lethality Serum clinical chemistry ~teessuultttss ffiioomm ssttuuddiieess iinn rraattss,, mmoonnkkeeyyss,, aanndd hhuummaann wwoorrkkeerrssddoonnoott iinnddiiccaatteececlel!ullualrat~oxoixciciittyy iinn tthhee lliivveerr., 22000099..00007777 AMMurrgu.JsJaatmm2ee0ss,KK2ee0ll0lly4y Page 110f22 August 20, 2004 Page 11 of 22 For PFOA, the liver is @ primary target organ for both short-term and chronic FKeeffoeffrnee'mccPetttss~dyOoo,ffAPP,1F9Fth8OOe5AA;liPviianensrrtt'aaiotstossra((GpGertr'Iiaiimlfif,ait~thh'1y9&&t8a7tLL)goeoentnnggod,,rgc11ay99nn88o00f;mb;orOOlbllgossuotohsnnms&&ohnoAArknten-dtdyeeersrmis(sssBceauannt,d,en11ch99h8o8r3o3;n;eict al. K 22h0y0e0p0n2e2)nr.)pe.ldayTTs,hhiee1a9(ii8nnn5cco;rreiePnaaacsssreeteddoaolslirievveeiertnr awwnLeue,ciilgg1ehh9atr8td7dDo)ocNeassAnndn)ooctat.ynaandppopphmeeaaaossrlgbttueoosebbnmeevoaaanrrrkieeoessuuyuslslltty(ooBfafuhthtereeppbratuahtttoooecfcdefeleltlltouualllaa.r,r hii1nny9cc8prr5eee;raapssPleeaasssstiiianono(pprneeoerrooaixxnliic,ssioeomam1es9ee8ss7,,i;neeBnnnuddutoucepplnellhmaao~sfmDafiiNccefAe~at)elit,aiccn2uud0llu0hum2an;saaBbanleeddevmnmtiivhttaooiIccaihhouooumn&nsdeldryriWiaaaatlt((rlITiakbkccueeddt,eaad2ee0ttto0aa2ll;., BB(1i9Miee8agg5ele;lloPeeanttsaeta&lol,yo.,~W22' ae00t0x01a1ml)).a..,n1,PP9FF81O'O979A;A)B.hhuaatsseHnbibgeehheeoennfrfdssehohtosoawewl.s,nnl2tet~eoa30ada2cct;ttoiiBvvaealttiletevhett:ihahdeeuemPPgePePnAe&ArRaRWatixraoeelnlccaeeacppnett,door2r002; n(nMeeceatroloossinisseyaann&dd the appearance i Waxman, 1999).. the appeaxance in the serumofenzymes reflecting liver damage Higher doses lead to liver degeneration and the serum of' enzymes reflecting liver damage.. cynomolOOgnnusppaamggoeenk1188e,,yttshheewessreececoonnnoddt ffouubllslleppra~vraeagdgxraaafppthhr&ssttaa5tt2eess-wtthehaeatkaarddevvceeorrvsseeereeyfffpfeeerctitossdi.inn PPIFFnOOfSuS-t-,eexxcplpioonssieceaddl c1echyheneemmoimcsistotorilyygatvuvvstaaelhlmuueereofsisnrykggseteeynneesexrrawaamlleillrynyeahhtnaaioddotnrroaeebsccsooexvvreevrremeeddodanwwtitihettrshhiiaonnf5tt2wrwe-oowcomemveoeokrnnytr.thehscs,(o,Svaaeennardcdyahhtpiiessertttoiooalllodo,gg.ii2ccI0ana0ll2~vv)aaacllt,uueecsslinssihhcooawwl eedd - ~ecovery at the first exm'nination at six months of recovery (Seacat et al.., 2002) ` comp`"oT[uhhneedppsaaprrraaoggdrrauapcpheh odoinnffppeaarggeneet 11r88e smruelgtgsaaldidininncggacncacanenrcceberirorraiisssskkayccsoo.nnffuusseess PFOA PFOA and and PFOS. PFOS., The The two. two compounds produce different results in eancei bioassays. ChaCrdhoernonnioicmcaddi(ieebtteaanrriyygneexxlppiovoesssuurtreeumoooffrsrsaa)tssatttoothPPeIF~hOOigSSheccsaatuusdseeoddseaatlleooswwt-e-ldlee(vv2ee0ll piinnpccmrreeaiansseediiiennt)h.heeppTaahttoeocceelllluullaarI hhsaedehppeoaanwttooonmcce1eal0lll(buubellemaanr'iptgtueunmrmolooixvrrisessraaotrrumeeemllpioikrkroeeslll)iyyfaetttrhhateethoerrree.hssuiugl(tthtBeoeesfrrtaatdsnonuoosmenn-e-tggeaeesnntnedoodiWtoo(ax2xli0ilccapmmcpeeemcc(hh2ian0an0nd3iii)ssem;tm)I.kPPeT1dF~haOOecSSt hahlaass(bb1ee9ee8n7n) `rsSaShotoohhhwellerennnwiitueoussabkeeetlraaaell..ps. pe((or11on99sx99ei22s))oi;;mCCteaeasrpsemerosoeltiotffaeallr.b.aet((no22ir00.g0.0n11())hB;;eepSSrae~etaaiocaecuaaetmtlleeeuttlaaaanll.r.da((W2d200ea00nl22ol)a)m;;caeI,Th(h2tooa0mmk0fef3ono)rr;tddo]kg((ee22td00ha0e0r2e2)tw)))ailt.GGh(i1itvv9heee8nn7)tthhee rdd`aheetummhmoeoanrnnswststrearaaatttkteehdrdeellslapaeccovkkenloossefof fgigneeentxeorprtmoooxssliacooioft'ybtxoheoanfiftPiPghc]Fna~OivOhSeeyS,pb, eaPPetIoFn3cOOedSSelltusselhhraoomriuunalledddde.nnnooottmTppuarzm,eesotsaeerknntetinnaacti~iodisgsekkenotcohfefecrcwaaawnnsccieterh~retdtthouoeced h(i(ssnuttcmaaitfdiaissenttnisiceceaaatlldlltyoyhsesseiig-lgernnvieieffsilipcscoaaonnnsftt'elleyyxcpiiunnorsvmmueaazlsleeuesgtsh))gaewwtshthheseannvadednoobosnesi-einlnniggndweweaa~ras,esrstmsuhuirssneppeseedhnn.oddlTeedddurmeaalttoaroot'ninioenencsyyiheedaimrep.n'.bceeTTehwhweeeaesttunu~mmdedooousrr-ceeadnd iiiinnnnccctirrhdeeeeaanshseceidedghlldniiofdfesoetestim-iermeeersetrpciiososknvkeosoerffyeeexm~xcavceelessssssuillgiivlgveieerrk'setttlusuymmauoonnrrszos.on.l-ltAAinennedaiitntn'o,ccrtrtheeralaeessaseethmiionenlndttthh~ysyearilooaniitcddiot~fnhobsilhlslliiifpcciuubnlldaaeirrtwnccgeeelwlellanaasdddoneeonsnteoommanaad oioonbtbhssteheerrervveheeiddgvhiinin-dmmodasaoelleefetsetnchoooyrrc'vrfofeeiee~mm,'yaalimleenassvleiionsnlttihhsveeleihhkmiidgewgyhhan--sutddroonsss'eeeeelaggntrreioodnuutpptohooetrrr'seiitannrutmdereyceconovtveserirnyycggerrotohuuipsp fffieenmmdaialnlegess,w, aaannsddnonntoo other evidenee of thyroid involvement was seen in the study = TTrahthso.e ooPnncFcooOggAeennwiiaecisttyyfooofufnPPdIF~tOOoAAinhhcaarsseabbseeeeetnnheiinnivvneecssittdiigegnaactteeeoddfiintn rttweweoo ssteeuppmaaorrraattteeyttpwewsoo,--yyleievaaerrr,ffeeLeeeddyiinndggistsctueulddli,ieeassniidnn rppfaaartgnen.cq.crureePeanaFtttilOiccyAoaabccwisinnaeaasrrIvfcceoedeullnlidttnuutmtomsooirrnsts.cr.6re*_eaats(e(RedRiitwkkhieeetrth,,inp11ce99i8rd83oe3,xn, icaasennoddomfBeBtiihpcerrggooeelellitfceutetmaaatlloorr22st00y0p011el1))si,s~Tlhihgveeeenssreee,rtLatuluemlmyyoodrrirgesscmacoregccinl,izaendd ttfhrheaatqt urraaettnsstlhhyaaovvbeesaaerhhveeeiidgghhittneenrnaeetdds response to peroxisome treated with peroxisome ~esponse to peroxisome prolferator proliferators prol~femtors rel~at tiisvgeotnoeortahlelyr relative to other species, recognized species, 6ofAAannnuaampppupasarrueeannlttyiinnlccorreweaaissneeciiinndemmnacamemomfmaiarbryryofEaibbdrreonoadoaemdnaeosmnioansmt,hsasieesseen,pnaiitnictthhleeasPPlEc~OoOAnA-tto-tle~aegatrteoeuddp.ff~emmTahalleeeirrnaa:ttsd,,ewwnacasse ttohhfee rreessuulltt omcmofaanammtnmomualnardruyaystuttauaumlmlyoorrlssowiinn all es :oups wis within the range expected incidence of fibroadenomas in this pa~ficulm' all test groups was within the range expected for tis sain control group. for tt~is strain ofta based on Ihe incidence of rot based on hoifstorical historical conttol data 22000099..00007788 Me Tames Kelly Mr James Kelly AAuugguusstt 2200,, 22000044 Pugs 12022 Page 12 of22 tiinnuccmllouurddsiinnaggehhruuammraaninsn.s.hu~Tmhhaeenhhsueummdaanncssxiioggcnnsiiffsiieccaahnnaccveeeomofofttthhbeeesseeenttlouhb'eesseteturumvmoeordirtntyyeppexepsoiisss enndoowttoccrllkeeeaarrr.s. These These tA(`uAwvmvhaaioiicllrahassbbrlmleeeepddoraatatraeenfoiotnrrp'hehhuruumommxaaainnnssssoawwmnehhdooperhhoxlaacivvefeescsshhetasoddrhTsaloovinoegna-eottertr)sbmese~ehnmoaowatbntmsoeeernn'ietnewwcdriietitnahhseehhxyyipppnoootlslheiipdpsiiedwdeteommhrkieieccersrdc.xu.aungcgsesrs. (which m e potent pemxisome pmlifemtors in rats) show no ineiease in these three cancers. DeDveevleoloppmmenetnsta)lEEffffeeccttss ThibodePPaaauggxeee1199a1ooff(tt2hhee00rd3raaafftndccooLnnesswuttllctatattaiiloonn(r2ree0pp0oo3rr)ttmssauuggyggelesestatssd ttMhhaaDttHcIeectneontctossnttsuuidddiieeerssrooennviPPsFFinOOgSSthbbeyyHeals hBBToaahsssibeeeoddpdVVaeapaaleuluruxseessestutooaglg.ddei(isf2ftff0esr0rehe3nin)tst,,ainaandnidLnlckaionkereleeltyyea,ollo.waw(en2esd0r,'t,0h3vv)aallmsuupeeaesscyubbllaeaasasteediddoMnoosnnDhHddoeeuvtvloedellcboooeppnmmwseiiendtntehtaradllrcefaevefvficnestcinsts.g.. Athe A review of Health- review of those papem suggests this is inoolreet, and the speculation should be withdrawn ssattrmruuiccttnuurreT"aaTllhrhddeeeepefllrfiieeottcecdetrturasscatttaauuittrrveettehhooeofnnutmnittmchehteeipoeepunfu,fepepwscsshtsiastcoocefhf'bbPPiooFFrrOnnO)o)SStaaaininfdndfccelrlrcueuetdpdpeeerrdosso,ddetaueurnc~cadtattiitfovovleeetoocaaggtnnyysddssotdduunededvivpieceoelslssootp((pnwwmmatheheaininlctcthahrallteesxsxpttaauuummpddisiiienen)ssee((Twwhhheiisccehh . esSTtxhuiaidmbisoeidsneehhaaaruvevxepe,brboecedeaeunlnctccivooTennhdfeduutuenrtccsetttdioobebnlydy,ogwooyuuhsstitsciuihdddeeiisellasnbbooaotreraagaftetfoonerrecierteesasdlff,oloayrnu33dnMMre,e,fmfaaeinncsddtksabbobyylneEEp.PPoAsATtnh~raeeetssaeeelafarrfraccethhtpeeruorssfpsLLc)oaanu,cT, ehrensefor hheYxuuhpmmiebaraoinndmerreiianssutkkxaals, seedstsoesassels.s.mm.eeTnn(htLteaiustetetrhhateetaolpplooo2sgst0yan0aas4tttau)lldddieeesvvemelloeoppgmmeenenentrtaaalllleyeffuffeenccrttessmooaff'iPPkIa~ObOlSeS. oa at pups ~he effect on rat pups atof' at concern fo~ experimental doses.. (Lau et at. 2004..) entolopy Studies Ieratologv Studies In recent review pape, Lau eal (2004), characterized the PEOS teratology studies ss ffoolllloowwss::In a recent review paper, Lau et al. (2004), characterized the P]?OS te~atology studies as m""~LoIeueasttaetoolwlooigghiiccPallRssOtSutd(ieepsothhaaasvvseeiubbmeeeannndccoolnnddeuucmctteeddsliinsn)raaC,t,aarsabbeibttit,a, laa,nndd m20o0u1se;wCiathtPaYnOSct(palo,ta1ss9i9u9m; aGnodrlniteh,ium198s0la;tsH)e(nCwaoseodeteaal,l, agrecment betwen sbovsories and across species examined, nd 21099041;b;ThCilbuoisdleiaanuxetetala,l.,19209093a;; GWeotrtzneel~,, 11998830); HTehnewfoionddientgasl,arc in 1994; Thibodeaux et at.., 2003; Wetzel, 1983). "[he findings ate in scaatgteoernes~escemnineeedanrelatllrblyvoeut"unwnmse(eeeEmmnmamplrahk'bkaaoasbrbilalesteowswrhiiehedsenena)mdnmadtaaetecrrrnnoasalsleesffpffeebccctitessasaretxeattmaakkieennneidin,nttaoond eonside~ation." (Emphasis added..) efercnc"TeThdhissinssttuthmmemmdamrrayyhiicnnoLLnaamulcaetttaaolln((p2200o00r44,)) eeonnnccowmhoipmcaphsssLeasdutethhwdeeappaathppeersbbeyyioTIrhhii(bbaoosddt)eeaaauuuxxt,h,oeerttaall (2003), (2003), ~TTBehFhfOiiebSbro.eodnd(eeeeaAaducuxioneemtttphaaaell.n&trieeaoppfnotorrcptoeaepdndoesorunnldtmamiatstiacoetunersrnsrneaeapdllobaarennt,lddooddwne,ewvvLeehalliouocpphemmteLaelna.ntutaa(wl2l0aee0svv3aat)lhl,uueaaatstdeiionornineoss~siisna(elaraastttth)aaeannmuddtrhmmoeiri.cc.ieemeepxoxrpptooassneetdd 10 Pp~pJ{eaoaFovttssOsettlntoSosiat.ttthahaH(leAeoffwppiicneoonodsvdsmtieitnnnnrpagag.tastsaant.))lhlioeeTTnffhahffpuieeitcbabcthptoossoeddrooreesffaadPnuuPilosxxZOtcOsuSeetSts."s.lap.el.rd.BBo2(bfi2i0oers00tluth0o3n3wdd)d)ee,fdfffeLeoeocfucautitunnscsiddwetwstttehehaiaarltn.et.tm(mmoo2aibbt0icscse0eseer3rrmaa)vva,reeeleaddwdggppe&ee~nrnieemiegsrrmshaaaeal~ldgllrIyyiyythalLeaaee"tstssmttihhnssoeeeecrnnhhehssiiiiiggtmtPhhiiveTpveseeoOstt~Stthdldh-aaaoonnnsstee posed ris und sean osicity in themice aswel Theconlusion in Thibodeau tal levels. However, the authors note "profound deficits in maternal weight gain" in the PFOS- exposed rats and raaternal toxicity in the mice as well. The conclusion in Ihibodeaux et al ((2000033)) sstaattess:: ""IInn ssuummmmamryy,, eexxppoostsuue ~too PEOSdung PI:OS during pegazncy pregnancy led led to to ssiiggnniiffiiccaanntt pphhyyssiioollooggiiccaall aalltteerraattiioonnss iinn tthhee rraatt aanndd mmoouussee tthhaatt aarree. 22000099..00007799 AMMuarguJJsaatmm2ee0ss,KK2e0ell0ll4yy August 20, 2004 PPaaggee 11330off2222 ioinnbddsiieccraavtteiivdveeioofnfmmtaatfteeertmnuasalelsttoaotxxiitccieittymy,, aaass hwwiegehlll d2aosssattogeasa.nnaattoTohmmeiicscaealaldddveeefferecscttess oobouuubrttscedcoreovmnmoeeedfsssiahnx~eetehddl~ooosfsne~e-ot-udcdseheepepsemenaintdcdteaeennlrtmt aaGannetddnheccirgaaannhllbbdyoeo,sccahoogerreres'em.l.laoatutIeehsddeewswaeiipttaphhdebvbaerooredd'sdyye(0 be burden of the fluorochemical. Generally, the mouse appeared to be oaxleiscstsye"nsitiv species than he rt in tegard to he PFOS induced a less sensitive species than the rat in regasd to the PFOS-induced toxicity." indicateTsThhieencNNreOOaEEseLLfd fosortr'eccalieelffttdpepfaaellacatttese wwwaeasst5Ssmmepeg/i/knkg/gFdadatysaiaiynn2rraamttsgs/aaknngdd/d11a00ymmapgnl/dkkgg1//0ddaamyyg/iinkngmm/idicceae.y. dTToshheees,ppaabppueet~r nwoinoetdtrieaacttaitddneoocssrsieeensascsoroeedffa33ssteood2rr' s5mStmegmry/ngkad/pklag/dy/aedf.yaey.c.t(sTITawnnbelmmreieisccsee1e,,eassnntcdeimrnn2atalailntddsTeaehfteif2cbttomsdhhgeea/akddugxaa/deNNaaOOylEEanLL2d0oo01ff30'|I)mmmggTg/hhk/ekkgsgg/ed//dadvayaayl;d;uotehhsseeeasyyr, but e al wwwceueellrnleaatibbnoocMvvrieeetnahtseheesedo00at...ta11255HmmmBgggV///k.kgdg//dadaayyy. NOEL valu fom the PFOS monkeystudyused to derive the (Tables 1 and 2 in Ihibodeaux et al 2003.) ]~hese values me NOEL value fiom the P]~OS monkey study used to de~ive the all cusrent Minnesota HBVs.. toxicity,GGinivvdeennthttheheeouucnmcru'eermmeanarcrkkeaaobbflleeponnsaatttnuuarrteealoofffttsehhtcertsustcrautcutgruearnalelraaalbblnnyoorlrmmoawlaeilrittiideeosssaaennsddttthhhaee toohbbesseesrrtvvreuecddtummraaatlteearnnaall { dmormalites, nan risk ssessaent should be basedonthe valu forpostnatal ffcts ether toxicity, and the occurrence ofpostnatal effects at generally lower doses than the stmctttt'al abnormalities, human risk assessment should be based on the values for post-natal effects rather tthhaann tteerr'aattooggeenniiec eennddppoionintsts. RReperopducrtivoe aadnndduPPooscsttynttaatlailEEfvfftebceettss TibodeLLaaanuu,teatelta.la.l((22(002000330)3))rreeippnooarlttceeoddmoopnnanttihheoepnpoopsustbntlaiatcalaltieeovvnaalluuNaaettoiiononantooaffl'tthmhoeersstaaamlmieetyaaonncinmcaualrlsrsessdttuuatddiileeoddwbebryy 0{dTd(T.Tooh5asasi8bebbelsslomeedgtth22/ehakaaiinngunn/xbbLdL,iiaaraetytmuthh,ateddlat.eenafa(fdel2e.c.ac0t22t0ss003.p00)o%3TIis))hnhteepaITcNNchhtoOOeeumAAmLLpEBEdBaaLMLnDyiDoff;6oon5rrpveveuffamabffleieullciccectstessastffwiooooorannrsnstuts.hhrm3eeNv.rv8imeai8vtovtamnaplplauutaeaappttlssppkmwwooasosa.tsrspttaap1|slaimmtBtusygogm/uto/khdkcdggacta//uyhydderaar8NeyydiiOnccaooAartnnatBcletsoseeLwnnwwtlaaexarnrsasadtiiotohnne benchmark dose 0.58 mg/kg/day, benchmark dose values and at values ae highet than postpmrum day me higher than he 0 15 my/kg/day 6 in mice was 3..88 the 0 15 mg/kg!day dos used i theMinnesotaHBS mg/kg/day.. Both the NOAEL and dose used in the Minnesota HBVs the `adie SoSfiirmnPiilRlamOrl'Slyy,c,tathhlceubbleaetnneccdhhimmnaa3urkkMdd(oo2ss0ee0ss3)ffsoorrxpphooissgtnhtaeatrallhefafffncbctttsshiinvnattlhhueee33uMMsedoonnieen--daainnvddittnwwgoo--Mggieennanecerasattoioaon'ns bCsctaueumrndreceinehntsmt aoHHrIBBkPVVPsd.Oso. SsBBfceoeeannlcccauhhlmm5ni%taenrdkckhiddnaoons3sgeeMess) (((ls2sopp0ree0cvc3iaif)friiicacoaatluellslyhy,e,igfttfhheheecrtllsotohwfwaeienrormt99h5e35%M%v'acscluooPnenfFfuiiOdsdeeSednnrccieeenplrldiiomemdriuiittvcssitnooigfof'tntMhshteeiundnieessoatrae's shown in the able below. benehmm'k dose for' a 5% shown in the table below.. change) for various effects fiom 3M's PI~OS reproduction studies a~e 22000099..00008800 MANurilg.uJJsaatmm2ee0ss,KK2e0ell0ll4yy Page 14022 August 20, 2004 Page 14 of 22 LLoowweerr 9955%% CCDeLLvoeoflftothphmeeeBBnetennalcchhEmmffaaerrckktsDDaootss5ee %aannBddeBBneecnnhccmhhammrakarrRkkeIIsnnpttoeenr[snneaallLCeCovonenlcceennttrraattiioonn ffoorr' oy Study Developmental EtIects BEangdeplosin:t at 5% BenchmLaLBt(BkmVMgRkDDge,is~ptaoyn)se LeveLLl(BEugMW/mIClC);~ 22G--GeGeennn RRReeeppprrrooo///DDDeeevvv FFFyylPPPuuupppWWWeeieigigghhhtttGGGaaaiminn (((LLLDDD22211D)))*a (mg/kg/day) 0033440.34 (ug/mL) 32%26 2222..--GGGGeeeennnnRRRReeeeppppirrloooo/t//DDDDeeeevvvv FF1,~11LPLLiuititptteeW rrStSSieziiizegteeh(((tLeLLGDDDa44r4i)n))**"(LD21) b 00003333949 3333600 2211.---GGGGeeeennnn RRRReeeepppprrrroooo//DD/Deeeevvvv FFFyF11, LLPLuiittptteeiMrrSoSSirtiitzzzaeeel(i((eLtLLDyDDS(r45))L)*"0D) 0000..8883439 39 7771 2211.---GGGGeeeennnaRRRReeeepppprrlroooo///DDDDeeeevvvv_FF1Fy:y11PPPPuuuupppp MM MMoorroottzlaattalalilliiittttyyyy((((LLLLDDDDS54))))*~~ 000088883434 7l 883 *" b 2-Gen Replo/Dev 1:~ Pap Mortality Bid on serumslesBK GD21 Based on serum samples taken on GD 21 Basedonserum sp ake oe n GD. Based on serum samples taken on GD 0 (LD4) ~ 0.84 84 (Benningofgoat aes reappropiatefor compsorcad ms contains) . (Beghnning oi gestation values are appr~riate foI compalisOn to measured human concentlafions ,) fora 5%TThhiuunscs,,idttehhneecmme)oosfstotrsstttrhriiennsggeeevnntatrbbieeonnucschhemmnadrmpkokiddnotossseefr((looomwweterhrecc3oonnMffiiPddFeennOccSee tllieimmpirittooodnuncttihhveeebbseetnnuccdhihommsamirskk dose. dose adfaopoprpsprealool5xxe%iivmmealianttfecelildyy0e100n5.c33e44m)gmmf/opkgrkg/tkg/hg/de/dasdeyaayyvfarddroooismoseeu.t..sheeTTnchhdiyipssnooiiismsnohhtlisigggfhhureoesrrmmttohthnhaeinenk3ttehhMyeesccPtuoFurJdrOieyeSnnttrMMepiinrnonndeeusscoottitavaeHHsBBtuVVdibbeaasssieesdd on on a a dose level of 0.15 mg/kg/day from the cynomolgus monkey study develop"ImThehunusts,,altthhseetuvvdaailelusu.eessTuuhssieesdd sffpooerr'cHHulBBaVtVissonwwsoohuuolluddldonorbtebbdeeemmleootrreee ssftiolinmnggteehnnttriiffabbfaassceeoddnsuuupplootnanttithhoeen: port developmental studies. This speculation should be deleted fiom the draft consultation iepolt childh`oTTohdheeedx&rpaoasffuttraaellsss.oosusIugnggtgehesescttassosonenoppfeagPgeFO1199StthahanatdtttPhhFeeOHHABB,VVdSsevmmealayoybpbmeeenddteeacclrieesaatssueedddieftsooaaacrceccoaouvuanintltfafobolrre, and hdcthehufuisalsdutlthhthoeeosHHadfBBeeVtxVypssaocccsatuanonrerddsiirreeIcnttlltyyhaeaddedadrsreeesssosfppPootFteeOnntStiiaaallenefdfffPeecPctOtssoAon,ndccehhviiell&dloreepnnmwweinittthhaooluustttuhhdaaivveiisnnagglet0oaaavpapippllalybaylae, and default safety factor'. Epidemiologic Information Epidemiologic Infbrmation `Worker Monitoring Worker' Monitor ing years. A33MMbathhtaaessryccooonnfcddluuiccnttieecddalmmeteeddsiticscaa(llisSnucUlrluvvieeinilgllalnlicapeniodcosfef, fhuleoumtoaortocochlhaoegmmiicciacalallppparrrooaddmueuctctetirioosnn, wewonorzrkkyeemrre'sss ffaoonrr doovv1e1err 25 25 dydPieiFffaffOreesSrr.eeonnArtt hhPbooaFrrtOmtmeAoroynnleeoevfaaescslsslsiaanyyiinsscw))aolssrhhtekoosevwtwrsees(ddinnncooluppdaaittnttegernrlipooiffdassas,soshcoeicmaitaaittiooonlnobgbeietctwaweleepenantattmhheeessteeermmse,eaeasnsuuzryleemmmeeesnntatssndaann1dd1 PFOS or PFOA levels in workers.. Page 19IThlhaeeborrereaffetereresen,nccceeitooinnngppaagJgeoeu33rtntooal""oppoofssOssiibbclleecceffffueecctpoonnaallneetdvvEeenllissvoioofrf'ooonnnnmeeeahhnootlrrammlooMnneeed""iciisisnmmeiispsiulecbaalddiiicnangtgi. on P((1OOa9lg9lsse5eennt1h9eeattteaallfal..o.buo11nr99da99t8ee84lsae),)vcooaitftfieandgsestastutudJrdyoyadouoifrofnltraeeclppoornroocfeddOnuutcccrtctaiiuvtvpeieaohhtnioosolrniamanuolofnanievnesesdwiiEnannrCCkvooo#tttottsanaggmweeietGGnhrtraoPolvvEMeeOwweAdooris~ckekienrmruessmpiiunnb1l1i99c99a33tioaannndd c1o9n9c5etnhtaattfioounnsdabeolevveat3e0dpepstmradiniotlheco1n9c9e5ntmreadtiiocnaslisnufrivveeilwlaonIckeers with PF OA serum concentrations above 30 ppm in the 1995 medical smveillance 22000099..000088~1 MAMurrg.uJJsaatmm2ee0ss,KK2e0ell0ll4yy Page 15022 August 20, 2004 Page 15 of 22 + T"ThAhee1cd0rkaa%fftlincccoornnessauusllettaaittniioomnnerraeenppooe(rstttrooammdiiitotlss ltthehveeilreewssttaosoffottbhhseessreevnnettdeenanccmeeofnftrg'oomemmttphhleeossytteuueddsyy,,wwWhhhoiicchhhadsstttaahtetess tthhaatt:: hih"inAiggdheh1exe0s.s%t"t ll(eieSnvvtceeullldessoyaosfafebs' sseitenrriaumucmtme,aPPenFFmeOpOshAAtar,as,adialisltothhlaodoludeu.evtds,Je.ha)ldtwhiBaissosaadosssbysososemciraaivatsetiisdoonnaiswmwaaoasknsngccoooenwmnfnfpooculuoonnynddfeeeoeddusbnbwydyehbrbooodhfdoyarydmemtsahtaerssassdiol miAAnloldllreeffxiiv.v"eeId(.eeSmmtaputpldl6ooy1yy7ae.ebees~sTaawwcikititt,hhnegPPmFiFpnOOhoAAaaslcliesecvvoaeeudllndssteaadtbb.h.oo)isvveepB3o3to0e9dnpyptpipmammlaschhsoaaniddsfoBBauookndddnyyionwMMga,nastscsshoenIIrnfneoddwueeenxxsedessenr((oBfBopMMraIteI))tsteoormaffd2o2io88fl.oo.rr association between PFOA and estradiol levels more. Id. at 617. Taking into account this potential association between PFOA and estradiol levels confounding, there was no pattern of' = TTrhehepersescsceaantttteaetrrippolneltotsohtoanstneppsaatgrgaeedi66o11l66dooofefstthhneeoOtOvllasersnyeweetitnatalhl. i11n99c99r88eaapspaianpgpeePrrFppOrreeAsseeennxttpaaocscluleeraaerrvvisisuuaall representation tlnat estradiol does not vary with increasing PFOA exposure o As noted on page 617, "Simple linearegressionof APFsOnAo,tedtreoantepdaagsea61c7o,nt"i'Sniumopuslevlainsieaabrlr,egrelessuslitoend ionf ntthohseetanntaaittsuutrriaacllallloolggysooifgfn[[ieefssittclaaaddnitiooll]] with with coefficients" PI~OA, treated as coefficients .... " a continuous variable, resulted in no statistically significant The text thee futher states that "linear and nonlineas relationships, aking into ataIhcchaccetoomutuenanxttytpptboohteteeernonetntifiaautllhI~eccolobenniifofsooltouuagnntieddcseeprtrhassat(ethes"wsplpaeiencycieoiaaaflrllleayyfnfaadeggtnee,oaarnnnelisddnueBlBatMMeldrIIe)inlaaassntioowwenselsillhglniaapissfsi,ooctttaahhneketriinaccsgoosviovnacartiroiaiaatttieeossns with PFOA that may be with PFOA except for 17-11P in the 1995 analysis" on the biologic pathway of effect, resulted except for' 17-It-P in the 1995 analysis," in no significant associations `Accordingly, we do not believe it is appropriatoe suggest an effect on estradiol fiom PFOA given the lack of Aceordingly, we given the lack of' dffioinndndiionntggbsseiilnnieeeviietthhieetrrilsliinanepeaaprrt'ooorp~nlnioaontnellitionneesaaurrgmmgoedosedtleaslns.. effect on estladiol from PFOA * TTGrhhoeevxreeeffieenIre1enn9cc9ee3dda11n99d998819pp9u5ub.blliiIcenatttatiidoodnnitppirroeenss,eenhntotssrhmhooornrmmeoolnneeveeddlasattiaanffwrrooormmkemmreesddiaictcaa3llMss'uusrrvvDeeeiiclllalatanuncrce,e aaAitlCCaobotatttmaaaggee aaGalnnrtddohvAAoenungtitnhwwet1erh9lpep9,,w3oBBraeeknlledggriisu1u'9mm9l5eff..lvuueoIolrnsmooaccfdhhdPeeimmFtiioOiccnaAa,llhwppoerrrroomedduoulcncotetwiioeolenrnvpptelhllaasannnitatnsstwCwwoeoetrrrkteeeattrgeseesstaceGtddr3oiiMvnne',11s99tD99h55eecraaeanntwuddaI,11s99An99l7o7a,,baaamnndda aaDaslestsschooaocctuiiuaagrtthiioaotnnhndebbAeewnttwowtrewekeeeennrrpstt'hhselueeirvrvePPelIisF~loOOlafAAnPclFLeeeOv(veOeAlllsssweaanennrddteeelassolrtwraad1edi9rice9ltlh.8..5a)nIThdhaoteeeCppsonuubtbotlaltiigsasehdhedeGrddrepopsaavsppeeet, rrht'heaaefddridednrdwreiseansgssisnsngooitnthnhege DPPPFFFeOOcOaAAAt,maatnnhaddendhrheooAprromnmrtotownnseeteslasp,t,esbbsm:uuttvttehhieleladdnaatctaae aa(xOeelsddeiisnscceuutssssaeeldd1ii9nn9tt8hhbee)ffduulelllesssttnuuoddytyarrdee&ppooerrstts"]thW Weiitftihhndrreienssgppseeccottnttoo PFOA, the repoIt states: ""1P0P.FF3O0OApApppmrlooaddpuupccettaiirooenndwwnooortrkkteeorlssh aiinvn eCCoaolttttaeagrgeeed GGsreroorvvueem wweisituthhadssieeotrlttumlmevlleeelvvseellss up up tp[[oOoOsl3liss0teeinnpveptemtaasalsla.,o.p,cpi11e9a99at89)ri.8eo.].dn..bn.eo..tt.w.toeWWeheneaveddseiitddraalnntdoeoitrtoeloodbabsnsseeedrrIuvvsmeeeraauennsmyytrPsasiidFggiOnnoiiAlffilicelcaveavnneetltsls in these Antwerp and Decatus employees." (p 30) positive association between estradiol and serum these Antwerp and Decatui employees." (p 30) PFOA levels in 7A~ TIshthaeetiDsDeticecaealatltuymr saainngddniAAfnincttawwneterlqppuassdmurravvteeiiicllllamanoncdceeeflofwoccauussseefdditoobnnetPPwIE~eOOeSnS PaannFddOScclliiannniiccdaalel sccthhaeedmmiiioss;lxihieeossw,ev((eOOrl,lsseernnesteitadaullal 19986) i998b) AiCdoniangsgctnaenotnositsstrttiiaiccctassilolssnyhhsosowwiwgaeensdditfhit12chi.8aisspnmtmomqdou,deaeldltrawwetaaicsshimhhgiihoggedhhselltylymwiiennaaffslsluufueiretnnebccdeeetddiwbnbyetyehenoonnsPeteFussdOppySe,eccwiaififniitdcchaeeesmmtprpealldsooityyoreel;ieeohwwlohvhwoaoeslsveueeesrso,eefr~ue9mms2idPPpugFFa/OlOelSS. This employeswas ooncenttations employee was alsowas also obese (BMI= 128 ppm, the obese (BMI- 33), an important highest measured 33), an important confounder(Olsen tal 1998) in the study, with an estradioI value cortfbunder (Olsen et al 1998b) of 92 pg/dL, Ibis 22000099..00008822 MM Aru.rg.uJJsaatmm2ee0ss,KK2ee0ll0ll4yy PAauggeus1t6200,222004 Page 16 of22 in sum,the raf consultation reports reference to estradiol levels in iveCottage Grove workers iInn oinf ooisunnnfmeeoyy,remethaaaretr'i'sdsoxnmmaefpedtrdiceicoscaenalnlstusselumdtravvtieienoiiltlnlhlaeranenrcpceeeoflddetroo'seeenssrncenefodeotrtppepunrbrcoloevivcitiaddteeieosaant,tccaoondmmoirpopllhleelteeteevoeaavlnnesdrdianalalccfcicovumerdamCyteeootirfteeavdgviaieetewaGwaroovoffivttlehhaweeblbboerookddoeyynr's tcothhofiinssicneiifssnosstururmeea...taitiooTTnnshhepemreeeezppsiseiddnueetememdidiooiilnlnoogtgChioieccttreeaevvgfii'eeddleGeennrnccoceeevddedoopweeuossbrnlnkioeecttratsiiinnoddnii,ccnaattoeer thatthe that PFOA overall PI~ OA affects estradiol at the body of data available affects estradiol at the on concent~ ations measmed in Cottage Grove WOlkels MoMrtoraClailtity~SSttuuddiieess studies OO"dnnoppnaaoggteer22e00p,r,ettshheeentddrreaapftitdcceoomnnissouullolttgaaittciioaonlnrfreeippnodoriltntcgcosoonfnccslliuugddneeissfitthchaaatnttchheee"ffiiYnneddtii,nnggtsshoeofsftthhueemmmoiortrotnaalnliaipttayytgeys studies "do not represent epidemiological findings of' significance." Yet, the summary on pages 3al.s4osbaeysustheadtitnhetheepsiduemmmiaorlyo.gic data sre inconclusive. We suggest the language from the text 3-4 says that the epidemiologie data ate inconclusive. We suggest the language from the text also be used in the summary. CottageG"TrThhoeevdderiwaafofttrcckooennrsssuublltytaattGiiioolnnlirtleeappnoodrltat(r(ppdaaggMeeassndl1e99--l22(001))9dd9ii3ss)ccuuassnssdeesss ltthhseethooreriisgguiibnnasalleqmmouoretlntaatlsliitttyyusdstytuuddbyyyooff' + dAC`aAollfetetxtxaaagcnnoeddneGserurrl(o(t22va00et00i1wo1)n)o,,clwwikthekeilsisccnhhbdyuuissGneeiddgllaiailnnnantiimdhmeppaGrnlioodlvvlMeeiddlajajnonodbdbe-a-clcna(adl1le9Menn9add3naa)drr-ea-yynleeda(ar1ra'9.lese9oxx%pp)tsoohstseuuusrrdueeybommsafeatqtiaruiiex-xnftoAAskltlluttdhheyoxoucubeggyshhsttohhfee pcpdrao~oansvftfstatiactrteomecnecasdanunicltnceaettrilhoeaanmmucopoidntnaeggtsewwfdioonrArdklkieenerxrgssainwwndiitetthhrhemmsGrtuoidelrylei.tltahhrIaiafdnntahtteenendncayM yereaamernsssdeefeilmwn(pdp1lil9ono9gyy3mim)seesgnntout,i,dnhtykgiiestsroaaabssses3oo-cifcioniaacldtltiiuoeodnxnecdwweaisanssstonnhofoett `ccoonnfsiullmtaetdioinnstehpeorut,pdtahteendtAhelerxeaponrdternestdusdyt.o Ipfrtohveideearslioemrefiandddiintgoinsalgodientgaitlo be included in the consultation repolt, then the report needs to provide some additional detail at CottaT`gTheheeGGGrio-Jlvlileilaa(nnodrd laaanncddkMMtheaenrndedeoefll)ssattsuudadyyusuussneeoddgacdtumreaafttoiiroonnPFooffOeeAmmpepxllpoooyysmmuerenentt iiAnnstthhneeotCCehhdeemimniictcahaell dDDriaivfvitissiioonn acwctooonrnCsksoueultrltttasaagttSieioouGnnbrrsroeeeppvqooeurrt(et,o,nrttthhlaeeercrseekcawwtrheecerrhreeehofiabfos)mura'sspphrraooowssstmntaat~ttheeoagtccaaatonnencclefeoyrrdoxdenPeaeIat~othOhfssAthooebebxsssepeerelovvmsee~pddleiionnyACCehsehensemwmoiotciecradakllienDDditiihvvnieitss&iihooeannfPt EOA `wpparrroooarddtkuuieccortstniiooinnsSbnubuobuitsilaleddqiigunnogego.n.dt((isOeOusllressoeaegnlncah11t99eh99a8f8so4ar,,sehppox. w6uG11nm55tP)h)aFAtAOdodAdndilicyttoiooonncnnaeealnltoddrfaaatttthaiehohsaneasvveeaemmsspohhlnooo~wgw/neneemttshphwaalttooyceremkmeeppsdllooiinyyzmmttehheenentPt I~OA dCCoroionitgt'ttaiaarnggiaeeelsGmGiorsrroonavvoleetiatCCyhghseoetmmouiddcicaysabmllerDDtoiwigvveiaiestseniioofnnodxu((rOOsaeltlrssiueeomnnnoeePtftFeaalOml..pA22l00oc00yo33m3nae)c)enntTTthrhiaunutstis,oh,nettshhCeeahmaaessmossinooccgcaiiaealtmtiDiooipnnvloirrsyeeieppoeoonsrrttaieenndddthiinpnertothsheteate ooccvaareinngrccieienrnratmlmeomrorptorrtaleamltliailtttiyytiyoiisnssvvtouefedrityyyhebddieiffftiffwniidcceiuuenllgnttst.odouirinnattteeirroppnrreetot..f. eTTmhhpeeloooyrrmiiggeiinnvaatllinaauutththheoorxCsshttehhmeeimrcnasselellDvveeivssiscciaaouunttiiaoonnndaapggaraioinnsstsattte over-interpretation of' the findings.. associatIIenndttwhhieetuuhppdddeaafttieendditssettuourddyyprbboyybAaAlblleeexxaPannFddeOerAr ((e22x00p001o1)s),u,rpperloocssatttaaettgeeorcciaeasnn.cceeriFmmuotorhltCearlamiliottyyreww,aasisnnnoorttesssiieggnnndiilffyiiccaannttllyy p``aopsunusbbopllrciisoishashtteeeadddterrweecvviatinihecewedwreoofafifrntteihhteeefuttootrohxpxeicrrioocpbloroaelgbsoyleoegnofyPtIe'FPPdOFFaAOOnAdAedx((opKKoenesnorutnmreesedhdcyyoawteeeftgaaoanll.r.iee22ss0s0o00c44Fi))au,,tlttithhhoeeenrwuumipptoddharaettd,eeudidrnammtaoiorrotrentacaloeliifnttytylyddaa~taa (eoeommnbpppslrlcoooryysvtmmaeetedennetctxiaipnnecaatennerdeemxxi'tenteefrplinanaaralletlhnaatenhnreaapsllleyyessss)iie:ssnaatme0m-doo<na1ngngdtytehhdaoorossen(e0eww/t0iisth1th;oddwe1ef-faii<nnn5iitat(ees2os/oo1Icpp4m)r~;tooibo5bana-bb1lwlee0itcch(xx0dpp/uoo0sl8sauu)fr;lieeoanttnooodPPf>]F31OO0.AA (`((44ow7i/b22ts.9h.e)9ol.u)v.tefduTT/lehhlxsueps,le,acbwwtoeeerdacctaiainuuottnpiioaoorfnnesnaaugtgbhaaseiinesnseqstsut)ecc:inittt0aa-ttfi<ioio1nnndyittoeonagttrshhe(e0GG{i0illlIl)ii;ll"aan1nd-d<aa5nn(dd2MM /1e.an4n)d;dee5ll-<((I11990993(30))/0sst.t8uu)dd;yyarrneedssuu>ll_ttss10 without full elaboration of' subsequent findings. AlexandeITrhhee(2dd0rr0aaf1ft)t rrceeoppnoosrrittdnneoroteteedsstaahfifsiinnfddiinindniggnoogffdeeixxfccieescsssucleertrcoibnbrtroeovrvaprasescteuulalanasdI wddiiassseeaaussee niinn AAatlloeecbxxoaannnlsddieedrerer((22i00t00a11)). Accaaluuessxaaallnaadssessrooc(c2iiaa0tt0iio1on)n caaott ntthhsiiidssettriimemdee.,this finding difficult to interpret and was unable to consider it a 22000099..00008833 MAMiu.rg.u.lTsaetmm2ee0ss,KK2e0ell0ll4yy Page170f22 August 20, 2004 Page 17 of 22 GGeneneerraall PPooppuulalattiioonnEExxppoossuurree fold osPPaatggheean44lssettvaaetteelssittnhhawatot rgkegeenrnsee.rraall Tphoipuilpoaputnliaootimnoneoleevtvle.lss of of' orochemiea fluoroehemieaI substances substances are are abont about fen ten- fold less than levels in workels. This is incoixect. * 2bO2Oe00lls00saee00pnnpooeerffttotthaaxhlleiemC((C2ao2o0t0tt00eata33lggaaye)e)GprrGreeporppomoovvrreettheewweddoottmrhlhkekeefafommonrereccdcdeeoiinaawwcnnehhnossoteerhhrrauaautmvvmieeoccnwwoowonnoacrcrekskenenet1ddtr8raaoct4tnniiollopyynnpssiimonoft(PtfhhP9eFeF5PPOO%]F3AACOOIAAff6rro1ppom3rlmo0o.dsdsu1muur)ccvvt.teeiiioiollnAnllanaaantnrlecweeeeeaarittnopo ba(aOnentddaspDDepneercceoeatxttamiulm,awwt1oeo9rl9rykk9e;e5rrOpssl'pssmseeen;lrututhmmaelPP.mFFeO2Oa0AnA0c%nao)nnddcePPnFRtOOraSStioccnoonnwccaeensntt1lsa8tf.ii4oonpnsspmaavve(e9rl5aag%geeddCbbI ee6tt.w.w7ee-3ee0nn..111 )5.a0nAdd n22twpppeomlmp. (Olsen et al., 1999; Olsen et al. 2003c). + eITthhaeol gg2oe0nn0ce3rra0ll; ppOoolplsuaelntaitcitoonanl hhaa2ss00aa4vvaee;rraaOggseeeleneveveetllso looff2000..00004055bp~),ppmm PFOA PFOA and and 0040 0.040 ppm ppm PEO PI~OS (Olon (Olsen et al. 2003b; Olsen et al 2004a; Olsen et al.. 2004b.. ) "Tthhe duiffsere,nce in meansexu levels besween th genesalpopulationandworkersengaged : Tiinnheeuiistt,hhteehrrePPdIF~ifOOfSeSreoornr'cPPeFFiOnOAAmeffllauunocrsroeocrcuhhmeemmilieccvaaelllspprrbooeddtuwuccetteiiononnthiisse aagbbeoonuuettrtao twwl opoor oprudlead rtsiooonfe fammnaadgr ~nwmitois utlukddeeersffooerinPPgFFaOgOSeS.d aannddtthl~r'eeeeoorimmoorleeoorrddeerrssooffmmaaggnniittuuddee ffoorl PPFTOOAA.. `MmM'gainsrooffgEExxippoonssuusrree women"TaThnhede d&ataarftitbccuootnnsstsuuhlltetaasttoiiootnno erEepPpoAor.rtt ((Tpphaaoggeefsso44r,,m22a11t))iccoiintteesscommmaaerrgsgiifnnssomooffaeenxxppAoposrsuiulrree2f0foo0rr3cch"hiplilrddebbleeiaarmiriinnngag.ry Register notice, EPA indicted that it had completed it draft PFOA risk assessment and would dwdrroaafmftt""enEEaPPnAAd ddaoottccriuubmmuetenenstttffhooerisPPeFFtoOOIAA~P((AUUSSETEhPPeAAin220f0b003r3)m.).atAAionyyeecaaorrmllaeattseesrf,,loiinrnaaaaMnMaAurlpccrhhil222990,,02230000"p44rFFeeeliddmeesxinaalal ry R{sshuueabbgtmmisditirtetartit't,n0toomtoritrceoevhv,iaeiEswwPitAbbeyyitnaadcSSiocccniaievetenendccneeethdAAadtdtvhviietissShoocarridyyecnBBocoomesrteApdddl..e.vtie66sd99oirFtFysedddB..ro. aaRRfrteedgP0F11O66oA22v44i9r9.ie.s.wktEEahPPseAsAeshrhsaaamfss.ennnooAtttcayyceneodrt dwrcieeonleagualslsdyee,dd tthaatti&onafot,fntoher hobassoilteyteetpcroelnivmeinneadrytdheraStcieisncnespAprdovpirsoisI7teBoard to review the dlafl. Accoldingly, citation ofthe obsolete pleliminaty draft is inappropriate PFOA"iT~nfhhxeespp.rreeTilimhmieinnEaaPtryyAEEpPPreAAliddmiriaanffatrIryeeffdlleecactteedpdraaesmmeinisstuuenndddmeearmrsgttaiannnddsiionnfggocoxfpttohhseearppehhaaurlsmmianacgcookbkilinoneoetdtiilccossvooeffs rom PfeFmOalAe irnaisatwsi.thTohuet EadPjAusptilenlgimfoirntahryeidrlaapftipdrelseesnatendcemoafrgPiFnOs Ao,f caxnpdotsmhse uunsdinegrebsltoiomdatleedvealts fiom `fesmeraulmelreavteslswainthdotuhteaadtiutstiengnfdmoarartnhgeitiniorfaepixdpcolesaulrane*ce of PFOA, and thus underestimated rat serum levels and the attendant margin of exposme.9 bes popes hacia sum levelis he US. population of aul, childen snd the ily. The 8 ~hese papers chalactetize serum levels in the U S.. population oi adults, children and the elderly. Ihe he ShabShowedconent ln, ihe veition by 83 o sender Fos additonal references on three studies showed consistent results, with little variation by age ol gendei. 1;or additional references on `Sena porelabon soncenations, etHansen 1 (2001Kanaan os. (2004 in pss Kudo general population eoneen~ations, see Hansen et al. (2001); Kannan et al. (2004 in press); Kuklenyik et 008 ma 2M G03) al. (2004) and 3M (2003). *9 TIhtaee pprreelliimmiinnaarryyddrraafftt Iriisskk aasssseassssmmeenntt ddooccuummeenntt ccalccuulaateedd aanneessttiimmaatteedd rraannggee.ffoorr' mmaarrg~innss ooff eexxppoossumree (MOB) betwee human eam cocentations of PEOA ad theserconcentrations it ight Ue found (MOE) between human serum concentrations ofPl~OA and the serum concentrations that might be fbund wearin sa ht exprineed developmen fects i o-generaion eptodueve Sy in weanling ~ats that experienced developmental effects in a two-generation reproductive study. eiing at serum congenions of PEOAwere esi os adult vehitwser messed 24 Weanling rat serum concenlxations of PFOA were estimated from adult levels that were measured 24 ows hs owing. Use of oe al Fo ealsenconcent oa spl obined 24 ows afer houls ariel dosing, Use of'the adult 1;0 female scaum concentaation from a sample obtained 24 horns after heat doe1 gross underaimaeof he valu ely cist in weanling rats ven that female ras the last dose is a gross underestimate of the values likely to exist in weanling rats given that female rats ence vitally all PFOA within 24 hous Usof he acaunder.heuve ppiach oprovide an excrete Viltually all PI~OA within 24 hours.. Use of the atea-under-the-culve approach to provide an Svermge serum concentration cxrcts for this phaTasakinetc sus average selurn concentration corrects fbr this phatmaeoldnetic issue 22000099..00008844 A[ruast3e0,s204 MMrr.,, .Jlaammeess KKeellllyy August 20, 2004 Page 18 of 22 BBuutteennhhoofffeetft aall... ((22000044)),, hhaavvee pprreesseenntteedd aa rriisskk aasssseessssmmeenntt ffoorr PPlFZOAA tthhaatt taakes iinnttoo account he complex pharmacokinetic of PFOA (isingi ara unht crurve approach account the complex phalmacokinetics oIPI~OA (using an area-under-the-crave app~oaeh to lel crig femele ot sem vel). The ahr eps rine ofspose for mean calculate avelage female Iat serum levels),, The author's repoit malgins ofexposure for the mean `sseerurumm PPIF:OOAA ccoonncceennttrraattiioonn ((00..0011 pppprmm)) eessttiimmaatteedd ttoo bbee tthhee 95~ ppeerrcceennttiilee ooff genneerraall pooppuullaattiioon xposto be besween 1600 nd 3900 or various enports Toe magnof poste fot pot exposure to be between 1600 and 8900 foi various endpoints The margin ofexposure foi post- `nnaattaall eeffffeeccttss ffoorr tthhee mmeeaann sseerruumm ceoonncceenntbraattiioonn eessttiimmaatteedd tfborr tthhee 9955t*~ ppeerrcceennttiile genneerraall ppooppuullaattiioonn iiss 22110000... ((ITaabbllee 1100 iinn BBuutteennhhooflfeeftt al. 2000044..)) The PFOA marginsofexpos torte nthe draft conslaton port re insccne Ihe PPOA malgins ofexposme Iepolted in the draft consultation lepolt ale inaccmate and should novo std. Th sukaesion te man of expan 66 sirfclly and should not be used. l'he suggestion that the malgin ofexposme is 66 is scientifically sound and miading unsound and misleading. `EEnnvviirroonnmmeennttaallDDaattaa Page 21 ofthe iat repr ives a BCE ox PROS in egillsof4013, ig he OECD Page 21 ofthe dlaft repoit gives a BCP for PFOS in bluegills ofz~013, citing the OECD acumen. Howeve, ho OECD document make lst tis vag foo needle prion of document.. However, the OECD document makes cleai this value is for the non-edible poltion of tthhee ffiisshh oonnllyy.., Tlhhee eeddiibbllee ppoorittiioonn ((BBCCFF 11112244))wwoouullddbbee rreelleevvaanntt ffoorr hhuummaann hheeaalltthh aasssseessssmmeenntt,, aanndd tthhee wwhhoollee ffiisshh vvaalluuee ((BBCCIF3 22779966)) wwoouulldd bbee rreelleevvaanntt ffoorI eeccoollooggiiccaall rriisskk aasssseessssmmeennt.t. WWee ddoo ot undersind why 8 BCE fornondle prions of he ish would bs hs evan ala 0 not understand why a BCF foz non-edible poltions ofthe fish would be the relevant value to mention mention,. 3M apprcies he Deparment' forts n providing tis consulation, nd we ope the ffoolreeggooiin3nggMccoaopmmpmmreeencntiatssteaasrleethhheeelDlppfefuupllariintnmiimemnpptrt'soovveiifnnfoggltttshheeinssccpiirceoanlvtiiifdfiiiccngaacctcchumisraacccoyynsoofuftlththaeetcioocnnos,nuasluntldtaatwtiieoonnhoicepppeottlhte Fyn do appro, we wok appt sous waning Coyof ese comments a If you deem it app~)pfiate, we would appreciate yore fo~wa~'ding a copy ofthese comments to nerestad pic uch 3 ATSDR and ol athrtis interested pa~ties such as A~[SDR and local autholities.. 530 would be pleased provide anyadisonal infomation hat vl be ep the 3M would be pleased to plovide any additional information that would be helpful to the Deparment Depmmaent. DDCaiavnvdeeyDDWooueugcglklaavsse,,rMMhP,PCCWAAeshingion Co Cindy Weckwetih, Washington Co. Sica yous, Sincelely yoms,/~~"7"x ~-- MDMWiiiccvhaaiedel,l AAE.v~4iaS,nrottooonrromsent Heals, Safty and Regulatory Alls Ditectol, Environmental Health, Regulatory Affairs Safety and 22000099..00008855 M MAsu.rg.u.lJsaatmm2ee0ss,KK2e0ell0ll4yy Page 190122 August 20, 2004 Page 19 of 22 RReeffeerreenncceess:: 3M (2003). Environmental and Health AssessmentofPerfluorooctancSulfonic Acid and Its 3M Salts USEPA Public Docket AR-226 (2003). Environmental and Health Assessment Salts USEPA Public Docket AR-226. ofPeffluor'ooctane Sulfortic Acid and Its AlAelxeaxnadnedfrei,ii,BlBtH.y.H.*. ((F22i00n00a11l))..R.ep""oMMrotor.tTatDlaiilvittiyyssisttouunddoyyofEofnfwwvoiorrxkokenermtessneetmmaplpllaoonyydeeddOacatctuttphhaeet3i3oMMnaCCloolttetaaaglgteehGG,rSroocvvheeo.ol of Public health, Universityof Minnesoa, April 26, 2001 facility." Final Report. Division of'Environmental and Public health, University of Minnesota, April 26, 2001 EPA docket Occupafionat EPA docket AR226-1030:018 ttealth, School of' AR226-1030a018 BBeerrtthhiiaaueutmmheye,l, p|J.eaarnnfddlW Wuaolatlllaoaccoeec,,tKKa...n2(2c00s002u2)l)...foPPneeeslatfflhmUlaiunOodorlloOo;oopccettraaonnxooiatsteoe,,rnppeeerrpffrllouulocilfroeooroacctttiaaonnneeassnutdtllffmooinntaaottceeh,,oaannndddriNNa-l- bcithogyel-npeesirfsl.uTootoxoicctoalnoegsyulLfebtntaerms,id1o29e:th2a3n-o32l;.peroxisome pr'olifelation and mitoehon&ial biogenesis. Toxicology Letters, 129: 23-32.. BBiiecggeel,lxL,Lu.sBB,h.,eHHpuarutttitttc,, M MtE.uE,.m.,Flr;itanadmmuece,t,iSSon.bRR,y, OOp'e'CCrooonxnninosoror,m, eJl CpCr,.o.,alainfndedraCCtooorosoki,kJn.lm,CCa...l2(e20C000D11))ra Mechanisomsf tsM. eocxhiacnoils.msScoif,' 6e0x:t~4a4h.e5p5atie tumor induction by pei'oxisome proliferators in male CD tats.. Toxicol. Sci., 60: 44-55. BBuutteennihaoo(ff2f~0,;04II)L.L..L, ,D"DC-.h.aWWracGGtaaeyryilolzrao,tJirJ.oAA,n MoMfroioosrokere,f,orGGg.WWenerOOalllssepenonp,J,u.1laRRtooido&sniieeckxksps,oJ,sJ.uHHreMMtaoanpndederelfli,,uLLo.t.oPRo~.e. tZZaoonbboeseltle." R(2e0g0ul4a).to"rCyhTmoxaiccteorliozgayfiaonndoPf'hIiasrkmfaocrogleongeyra3l 9p:o3p6u3la3t8io0n exposme to perfiuotooctanoate..' Regulatory Toxicology and Pharmacology 39:363-380 BBuutteennhbooLffife,,1dLe,r,,CCPo,stoOa,lGGss,e,EnEl,tlccoGo, mma,bnbede,T, hCC.o,..m,FfFaormrrrdaa,rz,',P_DD,(,H2Ha00na2sn)esennT,,oxKKi..c,,iIwtwyaoaiif,H,Ha,m.,Jm.lounnugi,uRRmn.,., KKegennnnee,ddyy,, G, G., Lppmeeoisernffdtlluehuroso,TrPoo.oTo,cocOtxtaailsnnceooonslai,teoSGc((.iP,P,IaF~n6OO9dA:AT))2h4iionn4mm-ma2fa5bll7reed,ccyPy.nn. oo(2mm0oo0ll2gg)uu.ss monkeys ate oral dosing Toxicity of'arrnnonium monkeys afteI oral dosing for for six six CCaas~ee,, M.T, York, R G. and Butenhoft, J L months ToxicoL Sci, 69:244-257 M..T, York, R.G.. and ButenhofI, .1 L `potassium perfluotooctanc sulfonate (((22P000F01O1)S.).) OOinrrtaaaltls((.ggaavTraoagvgieec))acclr~ooSscssis--ff6oo0sstte(r5fii-n1ng)g,sstt1uu0dd3yy5oof1 potassium Gilliland, F D. & per'fluoTooctane sulfonate (PFOS) in Tats. Tox~col Mandel, 1S (1993)MortalityAmong Employees oSfaci P6e0r(fSl-ul)c, r1o0o55ctarAocidc. `Production Plant. Gilliland, F D.. & Mandel, Production Plant. JOM 35: 950-954 I..S. (1993) MottalityAmongEmployee~ JOM 35: 950-954. oJa PerfluorooctanoicAcid GGrfiifftith,`, ePFxDfDl.u. aoarnnoddocLLtoaonnngog,a,teJ1.EE..A((1m199880I)0nd.).. HAAnyriSgmmaAalslsottoco.xxiccJii,ltyy41sst:tuud7dii6ees-sw5wi8ti3hth ammonium anamonium pezfluorooctanoate.. Am. Ind. Hyg Assoc.. ~, 41: 576-583.. HHaannsseenncKKhTIa,,iCCalcleetmmeeiennzttaLLtAiAoo,,fnEEo1lr1gleafosnoinnc MMMuEEo,r,Jo.oIcohhhnensmsoiocnnaHIllLsLin((22b0i00o01l1)o.)g.icCCaolommmpaoptuoincuden-sds.-psepEcenicvfiifiircconqquuSaacnnittiiTttaeatctiihvvneeol 35: 766.770. characterization 35: 766-770. of o~ganic fluoroehemieals in biological matrices. Environ Sci Technol IIkkeeddaa,, TTc,.y, tIF~ouuckkhuurddoaam,,eKKP..,L,4MM5o0oriiel,,n1Id.,,ptEe~nrnooomxmoiotstooom,,eMMpr.,,olKKioofmemraaaiti,i,oTTn.. iaannnrddaSSiuuvggesar,, TbT y (1987). Induction (p1e9r8lu7o).riInnadtuedchon of of oEeocd~ctstoaa,ennSheestps'uouilmlffeooernnPiiceV-4easr5ecli0idad.ga.,nIIdNnn:e:pePPwreeorYrxoooirxxsktio~,smoo3mem0eep4ssr-o2iinln0if8BBei[oailtoiogaoyaiannnl~ddaMtMoeldievidgecirciibnyneye,,pHHerD.fD.lu.oFlf~aiabnhiaiitmmeidi snd and Ff. H. Sics. Sivs, Eds, Spmger Veilag, New Yo~k, 304-208. 22000099..00008866 MNAuiixg.uJJsaatmm2ee0ss,KK2e0ell0ll4yy APauggeu2st02001,222004 Page 20 of 22 JJoohhnnssoonnP,,rJo1jDDe..c.taaNnnddoOO8bbe9er0r,0, 3RR1.E.0E.2.0((011,9977R99i8ka)e).s AALbabsbsooorrrppatttiiooornnioo,ff'IFFncCC.--S90t552-4"PCaCulii,nn MmraNrt.ss aa(fftUeerrS' aaEssPiiAnnggDlleeocookrraealltddNoooss.ee. PBrOoHjQec-t1N18o0-809000337140)200, Riker Laboratories, Inc., St. Paul, MN (US EPA Docket No. 8(e)I-[Q- 1180-00374) Johnson, 1D, Gibson, $1, and Ober, R E. (1979) Extent and route of excision and tissue Johnsondd8,i9issI0ttD0rii3bb,1uu0tGti2ioio0bnn0s,ooonffR,itto$oktte3aarll,cLcaaaanbrrobdbrooOanntb--o11er4r4i,eiiRsn,mtEIa..ntrssc(1,aa9ffSt7ftee9rrbPaa)aussliiEn,ngxMgltlNeeen.i.tviv..a(.dnUdodSosrsEeoeuPootAfef]F;oDCCof-c-e99kx5e5ct-r-teC4Nti.coo.,nPP8ar~(noq6djj)eetcHcitsQts-NNu1oeo1.80- 00374) 8900310200, 00374) Riker Laboratories, Ine., St. Paul, MN. (US EPA Docket No 8(e)HQ-1180- KKaannnneann1KK,,v, aCCnoorWxssoooluliienniiNS,,,YFFaaalnlaagnndJdyyHs,szzA,l,I,dFlo:iiullsllmmKaaMnn GG,(,2KK0u0um2m)aarrPKKeSrS,f,iLLuoootggoaaonncaatttahhnaaennsuBBl,f,oMMnoaothheddanM MdAA,r,elO0al1tieNvdeerroo ,fI,ivoatnocWheonuiecaNl,sYinanhgumJHan, AblldoooudsfKioMm s(e2v0er0a4l) coPunetnr'ileuso.roEoentarnoensuSlfcoinTaetechannodlr(eilnatperdess) fluo~oehemicals in human blood fiom several countries, Environ Sci Technol (in press) Kennedy, G 1 , Butenhoff, J. Olsen,GW, O'Connor,J C. Seacat, AM,Perkins, R G., KennedBPyBei,ireeGgfgel.elLul,o,.,rL1oB.oBBuc,tt,eanMMnhoumosrtfppfeh,hy.yI,C.,LrSSi.,t.RiROc,al,sleaaRnnne,ddvGFFiaae.r.~wWrrsaar,~,i,OnDD'TCoGGoxnicn((22oo00lr00o;44g.)J)y..C.M,,(TT, 4hSh)eee3aTT5co1aoxt-x,i3icAc8oo4.llM.oogg,yyPooeffrkins, R G.., Perfluorooctanoate Critical Reviews in lh~:icology 34(4):351-384.. KKeennnneeddyPy,h, aGGrL..mL.a.,cJJorr..l. ((8t1919:88553)).4.8-DD3ee5rr5mmaal1 toxicityofammonium toxicity of ammonium perflcrooctanaate. perfluorooetanoate Toxicol. Appl Toxicot.. Appl Phatmacol. 81: 348-355. KKuuklkenlyexiekt2raZa,c,RytReiioeinicckahhndIJAAm,,eTTausululllryyeIImSSe,,nNNteoeeefddphhearamfmlLuLLoL,ro,iCCnaaaltlaaeffdshtot rAAgMMan..i. c((22a00c00i4d4)s.). anAAduutatoommmiadateteseddinssoohlluiiddm--appnhhaassseeerum andl. exu'acfion and milk. Environ SeiTechnol 38: 3698-3704 and measurement of perfluoroinated Environ Set Techno138: .3698-3704 orgamc acids and amides in human serttm LLaauu,, CC.,,,`eBBxufulttueeonarhkoooaflffkf;y,Jl..aJLLc.,,idaasnnddanRRdoogtgeheerirsrs,,d1]erMMiva.t((i22v00e00s4.4).).ToxTTihhceeoldd.eeAvvpeepllloo.ppmmPehenantrtamalalcttooolxxi.iccii(ttyny oopfrfess, available: on web sie) pe~fluoroalkyl on web site). acids and thei~ derivatives. Tox,tcol. Appl. Pharmacol. (in press, available LaLuau,,CC,,TTThLhiibbaoondddeeSaatuuexvx,e,1Jn.sRRon,.,,HHaL,annAss.oon(n,2R0,R0.G3)G,.,RERoxogpgoeesrrusst,1,eIt.MoM.P..e,GsGfrlreeoyiy,o,BBoc.EtEa..n,SeSttSaaunlntfotonon,anMMt,eE.DEu,.t,BiBuntugeterlkaohtofff,, PPIrrLeegg. nnaaannndccSyytiiennveRRnaasttoaannn,ddLMM. oAou.us(s2ee0. 0t11I3...)PPoosEsttxnnpaaottaaslul rEEevvataloluuPaateti~ioofnnl.u.omTToooxxciitccaoonlle Sci 74: 382-392 Sulfonate During Sci 74:382-392 MMaalloonneeyyb,,yEEs.tDDrucaatunnrddalW Wlyaadxximvmeaarnsn,e,De.n.DI.vJ i((r11o99n99m9)e9.n)ta""lTIrrcoahnnessm--iAcAacclttsii.vvaaTttioioxonincooofflPPAPPpAAplRR. aaPllhppahhraamaa,nrdd16PP1PP:A2A0RR9-gg18aa.mmmmaa by structut ally diverse environmental chemicals.. Toxicol Appl. Phatm., 161:209-18.. Nokes, Noket; Pp2.e.rEEf..lsaaonnrddooGGcotorarnmmeaasnnu,l,fGGon.SaSt.e((i22n0000th33e)) cyAAnoppmhhoaarltmmgauacscookmkioinnneketetiyicc. ssttuSudodyuytoohffepproottRaaessssseiiuaurmmch Institue. npublished report Available on USEPA Administative Record 226 perfluorooctanesulfonate in the eynomolgus monkey.. Southern Research unpublished repor~ Available on USEPA Adminislzative Record 226. Institute. OOllsseen,nGG,JMW W,, MCCahhnuttdrreechlh,,T,TRIL,R,Z,LoLabarersslooLn,n,E,ER.. BB(,.2,0vv0aa4nnsB)Bele"llSleee,,rGuG.m..,:, LLcuuonnnddcbbeeenrrtgrg,Ja,JtiKK.o,o.n,HfsHaannsseenn,KK,..1. l,.., Burrs, Broils, pWpIeearM~sffhl.l,iuuonoMrgrooatoonoccdnttea"alnn,eeJCss.hu.uIleLlffm,oooZnnsaoapttbheeeelaar,nneLdd5oo4Rtt.(~hh1ee(1r2r)0ff:0ll1u4u5oao9)mr.9.o-cc1h"h6See1mme1iriuccamallsscoiinnncaaennnee~ll'dadeteirrollnyysppooopfpuullaattiioonn from fi'om Seattle, Seattle, Washington." Chemosphere 5~(11):1599-1611. 22000099..00008877 Mr James Kelly PAMAauurgg,g.euu,sJ2satt1m22eo00sf,,K22200e0l0l44y Page 21 of 22 OOlslseenn,, GOQuWW an,t,itTTa...tRRi.v.,e, MMEiviallllleuera,rtKK,i.o. nHHoaafnnPsseeefnnl,u,1J.o..rBBoouttcttltiaisn,|,cJs.uBBluufttoeennnahhtooeff(tf;P,|IF.OMMSa)anndadeneldl,,OLtL.h. eZZroobFbeldluor((o22c00h00e44rbbm))i.cals iQnutahnetiStaetrivaemoEfvCahliuladtiroenn.of'JPeC~hfilludosteono'cstaHneeaslutlfho2n(a1)te: (SP3I:7O6S) and Other Fluoiochemicals Olsen, GinWth,e SBuetreunmhoofffC, hJiLl&,eMna.nJdeClh,JilHc_ken(2's00H5e6a)lt"hAs2s(1e)s:s5m3en-7t6oflipid, hepatic and thyroid Olsen, GfPfiua.mWnuccl.ti,(iooBMnnNuii)tnen:nrr3heeMlolaafCttfioi,oom.nJnpLtato.on, yaaMn.aooncJcdcuceunulpe,paaJt9ti,iHoo2nn0aa0l(l23bb0ii0ooE3llaoPo)ggAii"dccAollsicimsmkeieistttsvvAmaaRlel-uun2eet2off6oof'~r-l1ippp3eeid5rfff,1llhmueoopooaootciccitaaannnoodaatttheey.""roSSidtt. OOllsseen,nGG,MPeaduWWdl,(i.M,zCCaNhdhu)ei:rn3hccMkhha,,sCTIh.o..imR,R,pZ,Ma,MinNyillo.ll.beJeriu,lrnJJeePtP9,,.,),2BB0Bum0r3,ltiOss',E,NJJP.e. AiMMl,ld.,LoELc.ukunMendtdbAb,eMeRarrg-ng2,d,2el.6Kl-K.,1,.3I,H5HHet,e.r~rxZooonbn,eRR,l,MML..,R, R(M(22e00ed00d33hC5bdr).o)iz.sas""dPPaeedehrurkflfatllusulhooorir,oooZoodcc.,itdaaNonnoneebsosuuirlllseff"tootinn,Eaa.ntt1veeiBaar.onn,nddO.oo'tNtHhheeeearirllltTf,fhuuEoPo.rerMorocse.hp,heeeMmcmtia,cincada1lels1sl,1iin.1nI..6ttHh)hee.,1ssZ8ee9olr2ubu-mem1l,9oo0Lff1..AAR[mmEesretriaicctaaunnm iRneEdnvCirroosns. aHdeuallt tbhloPoedrsdpoencot.ls.1"1E1(n1vi6r1o9n0. 0H]ealth Perspeet, 111(16):1892-1901 [Erratum in Environ.. Health Perspect., 111(16):1900]. OOlslseenn,, GGwoWW rk,e, rBBuusrrretixiss,u, J1p.M.eM.l..u, oBBrumooslceltwea,nwM c,suMMlM,f.,oMaMannatdneed(lePl,F, JO H. SH).. a((n22d00p00e33r)cf.).uoEErppoiioddceeirmasniooolltoogegii(ecPaaFssOsseAess)ssmmeenntt of of' cwcooonrcnkeecnrtersaentriuotmnrsptaaennldftdlmumieodeomidnociccasatlal nsseuursrvuveelifiollllaaannntcceee(eePxxFaaOmmiSin)naaattniiodonnpsse~JJfluOOoccrcocuoupcp.t.aEEnonyavteMM(ePeIdd~O44A55::)226600--22'7700 Olsen, Olsen, GGhe.WWp.a,.t.,iBBc tuemnrziisy,m,e.Is.1M,M,.c,hBBoultruelsleteewwr,,olMMaMnMd,.,liaapnnoddprMMoatarenidndesell,i,nJJaHHmm_(o2(n200i00u00))m pPPel]raafslsmumoaaroccohhcooilaleenccoyyaststetoo.kkiinniinn and and production workers.Drug Chem. hepatic enzymes, cholesterol and production workers. Drug Chem. Toxicol. 23:603-620 lipop~oteins in ammonium Toxicol. 23:603-620. pe~fluorooctanoate OOllsseenn,, GG`a.WnW d,h,eBBpuattmsici,sa,n1ldM M,li.,pMiMad ncalndidneeicll,a,lJcHJhHe,,mZZiosobtberelyl,,tLLesRRs_.(in1(19f99l99u)9o.r).oScSheeermruiucmmaplpeepr~frlolluduouorcrotooiococtntaaennmeeplssouulylffeooennsaatteeJ Occup Env. Med. 41:799-506 and hepatic and lipid clinical chemistry Occup. Env.. Med. 41:799-806. te~ts in fluorochemical production employees. J OOllsseenn,, GGwi.WWth,.,Oceetctauallp...at((11i99o9n98a88la).)E. xAApnnosEEpupiirddteeoemmPiieoorllfoolgguiicccroIIcnncvvteeassnttoiigigeaattiAioconindo.offRJReeppOrrcoocdduuupccttiiEvvneevHHMooerrdmm.oon4ne0e:ss6ii1nn4-MMeenn 6w6119i9t.h. Occupational Expostue to Pe~fluorooctanoic Acid.. J Oc~p Env Med. 40:614- Olsen, Olsen, GGof.WWCi,i,nBBiuc~rarfliisCs,,heJ1.mM.Mi,s.t,MiMaensad,nedHlee,l,ma1LtHH.ol,ZoZogboyeblael,n,dLLH..RRor. m((11o99n99e88bsb)).i.n R""eAAlnantEEipopniiddteeommSiioeolrloouggmiiccLeIIvnnevvleesssttoiigfgaattiioonn oPPAefeRr~C2ffl2lliuu6nooi0rreoo0aooI3cc0CttaahnneeemSSiusutllrftiboennsa,attHeeeiimnn aMMtaoallloeegFIyHluauonordrooHcchhoeermmmiioccanalelPsPrironoddRuucectltaiitooinonnEEmtmopplSlooeyryueemeess""L..evEEePPlsAAoDDfoocckkeett OOllssoonn,, CCApTeRxr.f.2al2aunn6odd.r0AoA0dn3endc0daeentrossiocno,anMM,c.EE.ii. n((m11d99a88l3s3e).).atITshheeaadaccueufttfeeetctootxxsiicocinittyytoiofsfsppueaefr~afftlltuuyooarrcooioocdcistaannooTioixccicaaonnldd. Appl Pharmacol, 70: 362372 perfluomdecanoic acids in Phatmacol., 70:362-372 male rats and effects on tissue fatty acids Toxicol. Appl. PPaassttooomr`,,StTTuP.dP,i.e.,LsoLefeee,,sKKmmPPo..s,PiePruerm~iip,,eMMrfAlAu,o,raaonnoddciGGainillollaieetsss,,-PiPn]Jd.u((c11e99d887h7)e.)p. aBBtioioomccehhgeeammliyiccaaanlldaapnneddrmmoxooirrsppohhmoeol.looggiiccaall `proliferation. Exp. Mol Pathol 47: 98-109. studies of ammonium pet'fluorooctanoate-induced proliferation.. Exp. Mol. Pathol, 47: 98-109.. hepatomegaly and peroxisome RRiikkeerr ((11sa99t88s.33R))ikTTewwroLoabyyoeeraaarrtororaraille((sdd,iieIetn))c.ttooxxEiixccpiitetyry/i/ccmaae~rncctiinnNooogg.eenn0iic2cii8tt1yysCtsRtuu0dd0yy1o2of,fffMlluuaooyrroo1cc9hh8e3em.miicceall FC-143 !~ C- 143 in in ~ats.. Riker Laboratories, Ine., Experiment No. 0281CR0012, May 1983. `SSeeaaceaat,t, A`ABuMM te,c,hoTIfhhfoo,mmf|foLm.rdd(,2, 0PP0I.3.l,).., HHaSanunbss-eecnnh,,rKKonJiJ..c.d,CiCleletemamreeynn,o, xLLiAAc.i.,,EyEolfdrdpiodtgaer s,sSSiRu.Ri m,.,EElldccoommbgbee,, CCe.X.R,,, aanndd Bppeeur~tffelinuohororootofoc,etItaaLnne.ess(uu2ll0~f0ob3nn)aa.tteeSiuinnbrr-aocthtss.r.oTTnooicxxiidcciooelltooagg~yyyt11o88x33:i:c11it11y77o--f11p33o11t.assium 22000099..00008888 MAMurrg.uJ,sJaatmm2ee0ss,KK2e0ell0ll4yy Page 22022 August 20, 2004 Page 22 of 22 SSeaceat, A(Aa2.M0M0,.2c.,)TThhasooummbfcfotlorv~dodn,,,iPPcI5t,o,xiHHcaaitnnyssesentu,ndKK,ic.sJ1,,oOOnllpseeenfn,l,uGGor.W.oWc,t.,aCCnecassscue,l,fMMonT.a.T,te,aapnnoddtaBBsuustiteeunrmtkhosofaftltt,;iJIn..LL Cynomolgs monkeys. Toxicol Sci. 6: 249-264 (2002) subcbJonic toxicity studies on peIfluoroctancsulfonate Cynomolgus monkeys. Toxicol Sci.. 68:249-264 potassium salt in `SSoohhileennPiiuuesrs,,flAAu.oKKr,o.o,cEEtrlaiinkckssssouslnof,noAA,n.iMM c ,a,cHiHdooiggssstrrpooomtme,nC,C.t,.i,KnKidiummclelaraonnfd,dpMMe,r..oaaxnniddsDoDmeeaPPliieefxrtrreye,,Ia1.c. iWWd...be((t11a99-99o33x))idation `PPaahnenadrdrfolomtutahhoceeiororal'oca.ctcittaTvionvixtieitiiceseosusll.fkkon7nn2ooi:wcw9nna0ctt-iood3bbisee aaaffpffoeectcetteneddt ibbnyyduppceeerroroxxoiifs'spooemmioeexppirrsooollmiiffeaerrlaafttaootrrtssyiianncmmidoobuuessteea-lioivvxeeirdr.ation Pharmacol. Toxicol. 72:90-3 TThhiibboodde`aBeuuatxeu,n,1hJ..o. fRRf,,.,).HHaaLnn.,sSsotone,nRvR,eGn.Gs..,RoRnoLo,g.geeArr.ss,,|a.!n. dM M,L,GaGruereC,yy.,,(BB2.0.E0E3,),.BBaaEtrxbbepeeo,eBsB,u...rDDoe,..,RpRairiccfhhluaaorrrddosos,s,JJt.anHHe,., sBsTuuoulxlftifeoconornllhaa.toteefSfcdd,iuiJnr..ii7Ln5n:gg, pp3Srl6teee9gvg3nen8ana1nnsoccnyy, in 1at nd mouse. I L.. A., and Lau, C. in rat and mouse. I: Matera nd prenatal evaluations. (2003). Exposure to pelfluorooctane Maternal and prenatal evaluations Toxicol. Sci 74: 369-381. TThhoommofnb`drDd,a, PwP..e1Ir,.,aStSseeaeafcctaeart,tAeA,tMMm..eaannddideBBtauurttyecneahxhpoooffIst;uJ,.rL.eLLto((N22-00c00t22)h).y..lp"Te[eerirfmmlivinnoaralolooobcbstesaernIvevasatftiuioolnnfsosniiannmiSSdpporraaggruce-eDtahwanloel.iatTsoxaifctoelr.lifSeeitim6e6 d(i5e-t1a)r,y1e8x5p-o1s8u6re(AtbosNtr-aectthyIDlp: e9~0f7l)u.orooctanesfulfonamido ethanol.. TaxicoI. Sci 66 (S-l), 185-186 (Abstract ID: 907). UUSSEEPPAA,t,o""PPPerxreefllliimumoiirnnoamoreyyt RRiisskk anoie AAAsscssieedssssammnedennitttosofSftathhsee,D"DeevAvpereliloolppm1me4ne,nt2t0aa0ll3T]?ooxxiicciittyy associated associated with with exposure exposme to Pe~fluorooctanoic Acid and its Salts," April 14, 2003 22000099..00008899