Document 8R4Eka7VDRkpn35RneLQb29ma

THE JEFFERSON MEDICAL COLLEGE OF PHILADELPHIA 1025 WALNUT STREET DEPARTMENT OF PREVENTIVE MEDICINE DIVISION OF INDUSTRIAL MEDICINE July 1 19A9 Dr, Robert A. Kehoe . Kettering Laboratory of Applied Physiology University of Cincinnati College of Medicine Cincinnati 19? l-'hio Dear Doctor K ehoe: I wish to thank you most sincerely for your extremely kind answer to my last letter; I really feel ashamed that .1 have taken so much of your time. I find myself in complete agreement with your statements. I was speaking, of course, of group examinations and not of the investigation,of an individual case of suspected lead poisoning-. Unfortunately, conditions prevent, in general, the collection of large samples of urine in the group examinations. I am continuing the correspondence you had with Mr. Bowditch concerning poisoning due to the ingestion of wax crayons. I have observed one case and have seen detailed reports on about nineteen other cases. We also have conducted some experi mental work here and in co-operation with Bethesda. There is no doubt that ingestion of wax crayons and especially ingestion of the pertinent finished dyes produce methemoglobinemia in a rather large percentage of cats. Much more work will be necessary to es tablish how and where re-forming of intermediates takes place; it does not happen in the stomach, and intravenous injections of sus pensions of these dyes are without effect. I hope to continue this 'work which seems to be of a rather interesting nature. Thanking you again for your very kind and very helpful letter, I am Very sincerely yours, *" * , H. Brieger, M. D. Associate Professor and Director Division of Industrial Medicine 0019997