Document 8Kjx8wNQVKOkMbxqEB0Ekk1B

Only nickel, lead-lined, glass or porcelain equipment should be used for anhydrous benzyl chlo ride. This includes valves, fittings, piping, agitators, controls, pumps, etc. Iron or other me tallic contamination must be prevented. When using iron or steel equipment, or that fabricated from materials other than the recom mended list above, use only the emulsion (stabilized) form of benzyl chloride. It is advisable to wet the equipment with soda ash solution just prior to contact with stabilized benzyl chlo ride. It is also a good precaution to maintain a small amount of soda ash solution in any iron or steel vessel that is used for stabilized benzyl chloride. Warning: These above precautions are necessary to prevent possible prod uct decomposition that can attain explosive violence. The emulsion (stabilized) form of benzyl chloride should be used as rapidly as practical in order to avoid excessive storage periods. This is to prevent a possible build-up of a dangerous pres sure within a storage vessel, occasioned by loss or dissipation of the stabilizing solution. However, Monsanto stabilized benzyl chloride, in standard containers and under normal storage condi tions, exhibits no pressure build-up in periods of as long as two years. Sampling equipment should be thoroughly cleaned before samples are taken. A recommended procedure is to rinse with C. 1\ hydrochloric acid until iron free and follow with a distilled water rinse. Sample bottles should be dry when working with anhydrous benzyl chloride. The bottles should preferably be of the ground glass stopper type. TOXICITY Care should be exercized in handling and using benzyl chloride. It is irritating to the skin and its vapors are highly irritating to the eyes, nose and throat. Contact with the skin and breath ing of the vapors should be avoided. It should not, of course, be taken internally. In case of accidental contact with the skin, wash the affected area immediately with soap and water and secure medical attention. If it is splashed in the eyes, flush them thoroughly with water for at least fifteen minutes and secure medical attention. If benzyl chloride is accident ally swallowed, induce vomiting immediately, using mustard and water or other emetic, and secure medical attention. Ventilation should be provided, whenever possible, to maintain vapor concentrations below an irritating level. In all other cases, respiratory protective devices, such as approved gas masks or respirators should be used. In addition the use of various combinations of other protective garments and equipment, such as rubber gloves, rubber aprons, rubber shoes, goggles, etc., is advisable. All protective garments and equipment should be clean before use. If a spill occurs dissipate the benzyl chloride by flushing with a large amount of water. If that is not possible use materials such as soda ash or lime to absorb the spillage, sweep up and discard, and flush the area with as much water as is available. 3 0196627 TOWOLDMONOQ24761 CHEMICAL INTERMEDIATE .. Santochlor undergoes sulfonation, nitration and other reactions characteristic of aromatic mol ecules. It is used as an intermediate in the preparation of certain specialty dyes. INSTRUCTIONS FOR HANDLING SANTOCHLOR />ara-Dichlorobenzene, when handled with ordinary care, should lead to no ill effects. How ever, it is not intended for internal consumption and should this happen inadvertently, an emetic such as mustard water should be administered. A physician should be called. Care should be taken to avoid prolonged inhalation of high concentrations which may occur iq a confined space. If concentrations are sufficiently high, tearing of the eyes will occur. The U. S. Department of Agriculture, Farmer's Bulletin 1246, revised January, 1940, indi cates that ^oro-Dichlorobenzene vapors are harmless to persons and domestic animals under normal conditions. lj a person is exposed to excessive amounts of vapor, a physician should be called. If material gets into the eyes, they should be flushed immediately with copious amounts of water. During industrial manufacture, no reports of illness due to Santochlor have been reported in either the manufacturing or packaging operations. The information contained in this bulletin is, to our best knowledge, true and accurate, but all re commendations or suggestions are made without guarantee, since the conditions of use are bevc>nd our control, Monsanto Chemical Company disclaims any liability incurred in connection with the use use of these data or suggestions. * Furthermore, nothing contained herein shall be construed as a recommendation to use any product in conflict with existing patents covering any material or its use. AHS:M 4/40 Printad in U.S.A. 12 O 01966Z8 TOWOLDMONOQ24762 *** and aquatic midges24, in termite contror-5-20-27, a larvacide28-20-30-31,32, a fungi cide33-34, a vermifuge33-30, an insecticidal fumigant:l1:l83t,'4tl`41'',2'):t,44'45, a wood preBervative40-47-48-40-50, a soil poison and soilBteritant51-52-53-54 in the control of aquatic weeds53-30 and the protection of oysters57. Plastics and Fibers Ortho-dichlorobenzene has been used as a polymerization solvent58'53, as an additive00 and as a constituent01 in polymeric systems. It also has been investigated as a chaintransfer agent in free-radical polymerizations02-03-04. Ortho-dichlorobenzene is used as a dye carrier in the dyeing of synthetic fibers05 00 C7-080H, Wool70-71 and blends of polyester fibers and wool72. It is also used in the treatment of synthetic fibers with optical bleaching agents73. Other Uses Miscellaneous uses for ortho-dichloroben zene include its use in food coatings74, as an antiseptic for the storage of yams75 and a means to control the food-sterilization temperature70 in the food industry; as a freezing point lowering additive77 in hy draulic and dielectric fluids; an additive78 for sulfur-containing fuels for high-speed diesel engines; a cooling liquid70 for mag netic coils; a heat transfer fluid80 a reaction solvent in the manufacture of vat dyes81-82 and in sulfonations83 and as a solvent used in the purification and recovery of maleic anhydride84. Toxicity "Ortho-dichlorobenzene is irritating to the eyes and prolonged breathing of the vapors in confined spaces may lead to signs of toxicity. Therefore, continuous or repeated contact with the skin or prolonged breath ing of the vapors should be avoided." Safe Handling Ortho-dichlorobenzene can be handled with complete safety if the following precau tions are observed: (1) Provide adequate ventilation to avoid excessive breathing of the vapors. (2) The material should not be allowed to remain on the skin or clothing for a prolonged period of time. (3) A burning or stinging sensation may result from skin contact, but unless an individual is sensitive to the mate rial, no skin irritation is likely. (4) If contact with the skin occurs, wash immediately with soap and warm * water. Shipping Information Shipping Classification (USA): Ortho-dichlorobenzol Shipping Regulations: Product label required by law 16 ounce sample mailable Standard Containers: Tank cars and ICC-17E steel drums containing 550 lbs. net. The following references were taken from the literature and are given to suggest additional applications for ortho-dichloro benzene. ' 0196 <>Zq V2 TOWOLDMONOQ24763 22-23 and aquatic midges24, in termite control25-20'27, a larvacide28'20*30-31'32, a fungi cide33'34, a vermifuge3*'"'1, an insecticidal fumigant:t7'3B-3l,'40'41-4-'43'w'45, a wood preservative4M7'4M0'50, a soil poison and soilsteritant51-52'53-54 in the control of aquatic weeds55 *0 and the protection of oysters57. Plastics and Fibers Ortho-dichlorobenzene has been used as a polymerization solvent58-50, as an additive60 and as a constituent01 in polymeric systems. It also has been investigated as a chaintransfer agent in free-radical polymerizations0203 04. Ortho-dichlorobenzene is used as a dye carrier in the dyeing of synthetic fibers05 60*- wooiio.Ti ancj blends of polyester fibers and wool72. It is also used in the treatment of synthetic fibers with optical bleaching agents73. Other Uses Miscellaneous uses for ortho-dichloroben zene include its use in food coatings74, as an antiseptic for the storage of yams75 and a means to control the food-sterilization temperature70 in the food industry; as a freezing point lowering additive77 in hy draulic and dielectric fluids; an additive78 for sulfur-containing fuels for high-speed diesel engines; a cooling liquid70 for mag netic coils; a heat transfer fluid80 a reaction solvent in the manufacture of vat dyes81-82 and in sulfonations83 and as a solvent used in the purification and recovery of maleic anhydride84. Toxicity "Ortho-dichlorobenzene is irritating to the eyes and prolonged breathing of the vapors in confined spaces may lead to signs of toxicity. Therefore, continuous or repeated contact with the skin or prolonged breath ing of the vapors should be avoided." Safe Handling Ortho-dichlorobenzene can be handled with complete safety if the following precau tions are observed: (1) Provide adequate ventilation to avoid excessive breathing of the vapors. (2) The material should not be allowed to remain on the skin or clothing for a prolonged period of time. (3) A burning or stinging sensation may result from skin contact, but unless an individual is sensitive to the mate rial, no skin irritation is likely. (4) If contact with the skin occurs, wash immediately with soap and warm * water. Shipping Information Shipping Classification (USA): Ortho-dichlorobenzol Shipping Regulations: Product label required by law 16 ounce sample mailable Standard Containers: Tank cars and ICC-17E steel drums containing 550 lbs. net. The following references were taken from the literature and are given to suggest additional applications for ortho-dichloro benzene. 0 196630 U TOWOLDMONOQ24764 CHEMICAL INTERMEDIATE Santochlor undergoes sulfonation, nitration and other reactions characteristic of aromatic mol ecules. It is used as an intermediate in the preparation of certain specialty dyes. INSTRUCTIONS for handling santochlor />oro-Dichlorobenzene, when handled with ordinary care, should lead to no ill effects. How ever, it is not intended for internal consumption and should this happen inadvertently, an emetic such as mustard water should be administered. A physician should be called. Care should be taken to avoid prolonged inhalation of high concentrations which may occur in a confined space. If concentrations are sufficiently high, tearing of the eyes will occur. The U. S. Department of Agriculture, Farmer's Bulletin 1246, revised January, 1940, indi cates that /wru-Dichlorobenzene vapors are harmless to persons and domestic animals under normal conditions. If a person is exposed to excessive amounts of vapor, a physician should be called. If material gets into the eyes, they should be flushed immediately with copious amounts of water. During industrial manufacture, no reports of illness due to Santochlor have been reported in cither the manufacturing or packaging operations. The information contained in this bulletin is, to our best knowledge, true and accurate, but all re commendations or suggestions are made without guarantee, since the conditions of use are beyond our control. Monsanto Chemical Company disclaims any liability incurred in connection with the use use of these data or suggestions. Furthermore, nothing contained herein shall be construed as a recommendation to use any product in conflict with existing patents covering any material or its use. AHS:M 4/M Printed in U.S.A. 12 TOWOLDMONOQ24765 STABILITY AND STORAGE Or///o-nitroani)ine is stable up to 270C and noncorrosive. It 'nay be safely stored in the origi nal fiber drums for a year or longer but might cake if exposed to high temperature and humi dity. TOXICITY AND SAFE HANDLING O/'/Ao-nitroaniline is a poisonous substance but may be handled safely if proper precautions are constantly observed. H may exert its toxic effect when swallowed, after inhalation of its dust or vapor, and after absorption through the intact skin. Skin absorption and inhalation of vapor account for most cases of industrial poisoning. When ort/fo-nitroaniline enters the body--by the digestive tract, the respiratory tract, or the unbroken skin--it complexes with hemoglobin to reduce the oxygen-carrying capacity of the blood. The early signs of acute poisoning include cyanosis--development of blue color of the lips and under the fingernails because of oxygen deficiency. This symptom may be accompan ied by a feeling of well-being but is followed by severe headache, weakness, increase in pulse and respiration rates and- if exposure continues-unconsciousness and death. Exposure to w/Ao-nitroaniline must be prevented by using wholly closed systems for handling and by proper industrial hygiene and engineering controls. The use of approved respiratory protective devices and protective clothing is mandatory in cleaning up spills, cleaning tanks, re pairing leaking equipment, etc. . After an exposure, the patient should be removed to fresh air, contaminated clothing removed, and all material washed from the skin with soap and water. Particular care should be taken to be sure that no or/Ao-nitroaniline remains in the hair or under the fingernails. If cyanosis develops, the patient should be put to bed in a warm, well-ventilated room and kept warm. Oxygen may be administered by properly trained first-aid personnel unil a physician arrives. For more complete, detailed instructions for the safe handling and usage of Yrr/A^-nitroaniline, refer to "Chemical Safety Data Sheet SD-17, Aniline" (Manufacturing Chemists' Association, Washington, D. C.). 3 019661P TOWOLDMONOQ24766 STABILITY AND STORAGE Or/Ao-nitroaniline is stable up to 270C and noncorjosive. It may be safely stored in the origi nal fiber drums for a year or longer but might cake if exposed to high temperature and humi dity. TOXICITY AND SAFE HANDLING Ort//o-nitroaniline is a poisonous substance but may be handled safely if proper precautions are constantly observed. It may exert its toxic effect when swallowed, after inhalation of its dust or vapor, and after absorption through the intact skin. Skin absorption and inhalation of vapor account for most cases of industrial poisoning. When 0/7/w-nilroani!ine enters the body--by the digestive tract, the respiratory tract, or the unbroken skin--it complexes with hemoglobin to reduce the oxygen-carrying capacity of the blood. The early signs of acute poisoning include cyanosis--development of blue color of the Ups and under the fingernails because of oxygen deficiency. This symptom may be accompan ied by a feeling of well-being but is followed by severe headache, weakness, increase in pulse and respiration rates and-- if exposure continues-unconsciousness and death. Exposure to or//;o-nitroaniiine must be prevented by using wholly closed systems for handling and by proper industrial hygiene and engineering controls. The use of approved respiratory protective devices and protective clothing is mandatory in cleaning up spills, cleaning tanks, re pairing leaking equipment, etc. . After an exposure, the patient should be removed to fresh air, contaminated clothing removed, and all material washed from the skin with soap and water. Particular care should be taken to be sure that no or/Z/o-nitroanilinc remains in the hair or under the fingernails. If cyanosis develops, the patient should be put to bed in a warm, well-ventilated room and kept warm. Oxygen may be administered by properly trained first-aid personnel unil a physician arrives. For more complete, detailed instructions for the safe handling and usage of or/Z/o-nitroaniline, refer to "Chemical Safety Data Sheet SD-17, Aniline" (Manufacturing Chemists' Association, Washington, I). C.). 3 33OV^bb TOWOLDMONOQ24767 Only nickel, lead-lined, glass or porcelain equipment should be used for anhydrous benzyl chlo ride. This includes valves, fittings, piping, agitators, controls, pumps, etc. Iron or other me tallic contamination must be prevented. When using iron or steel equipment, or that fabricated from materials other than the recom mended list above, use only the emulsion (stabilized) form oj benzyl chloride. It is advisable to wet the equipment with soda ash solution just prior to contact with stabilized benzyl chlo ride. It is also a good precaution to maintain a small amount of soda ash solution in any iron or steel vessel that is used fof stabilized benzyl chloride. Warning: These above precautions are necessary to prevent possible prod uct decomposition that can attain explosive violence. The emulsion (stabilized) form of benzyl chloride should be used as rapidly as practical in order to avoid excessive storage periods. This is to prevent a possible build-up of a dangerous pres sure within a storage vessel, occasioned by loss or dissipation of the stabilizing solution. However, Monsanto stabilized benzyl chloride, in standard containers and under normal storage condi tions, exhibits no pressure build-up in periods of as long as two years. Sampling equipment should be thoroughly cleaned before samples are taken. A recommended procedure is to rinse with C. P. hydrochloric acid until iron free and follow with a distilled water rinse. Sample bottles should be dry when working with anhydrous benzyl chloride. The bottles should preferably be of the ground glass stopper type. TOXICITY Care should be exercized in handling and using benzyl chloride. It is irritating to the skin and its vapors are highly irritating to the eyes, nose and throat. Contact with the skin and breath ing of the vapors should be avoided. It should not, of course, be taken internally. In case of accidental contact with the skin, wash the affected area immediately with soap and water and secure medical attention. If it is splashed in the eyes, flush them thoroughly with water for at least fifteen minutes and secure medical attention. If benzyl chloride is accident ally swallowed, induce vomiting immediately, using mustard and water or other emetic, and secure medical attention. Ventilation should be provided, whenever possible, to maintain vapor concentrations below an irritating level. In all other cases, respiratory protective devices, such as approved gas masks or respirators should be used. In addition the use of various combinations of other protective garments and equipment, such as rubber gloves, rubber aprons, rubber shoes, goggles, etc., is advisable. All protective garments and equipment should be clean before use. If a spill occurs dissipate the benzyl chloride by flushing with a large amount of water. If that is not possible use materials such as soda ash or lime to absorb the spillage, sweep up and discard, and flush the area with as much water as is available. 3 O 19663*1 TOWOLDMONOQ24768