Document 85JyymOw7EB568x1mExoqRQVe
16EXHIBIT
V
August 3, 1972
Dr. Alfred Weissler, Acting Director Division of Colors and Cosmetics Technology Office of Product Technology Food and Drug Administration Department of Health, Education and Welfare Washington, fl. C. 2020k Dear Dr. Weisslers
Enclosed please find my final analytical results on the mineral compositIons of 102 examples of standard, commercial products containIng talc. These include all the specimens you sent me from Washington, except for a few (princIpally the pharwsceutIcal specimens) which I 'iill report on separately, as well as a number- that I purchased in New York and in Boston.
The nlyses show that 59 of the products have no detectable amounts of any of the asbestiforn minerals (by the technique employed1 prpportlons by weight of 1-2% or less could escape detection). 20 had small but defInite percentages of tremolite, 7 had small percentages of chrysotile, 9 had small percentages of both tremolite and chrysotile, and 7 had substantial percentages of one or both of these asbestlform mineralt.
I shall retain and preserve the orIginal specimens, and the x-ray diffractograrns, until you advise me OtherwIse.
With very best personal regards,
J itSincerely yours,
Seymour'Z. Lewin Professoi' of Chemistry
INTERNAL 0771
ITA-LG 00200
TABULATION OF X-RAY DIFFRACTION ANALYSES OP COMMERCIAL PRODUCTS CONTAINING
TALC-
A.. Products having no detectable amounts of asbestiforrn minerals (limit of detectabillty=oa. 1 to 2% for each mineral)
Product
Ilineral ComDosltion
Talc ChlorIte Phlopotite c-Quartz Dolomite Other
1 70% 3%
2 a00% m.d.
3 99% nd.
4 100% m.d.
.5
-u
7
95,00'
2%
Qu4'ur9tIpdp'
2% 7%
8 95% 2%
9 89% 7%
U10 93% .3% 90$ 2%
12 13
120% 6o%
m.d.
ii. d.
14
- 31%
5o%
15 11 d.
16 --
17 6o% 30%
18 90% 4%
19 97pci 1% 20 35% 60%
21 67% 25%
22 59% .1 J
23 42% 50%
24 94% 1%
25 95% 2%
2
95%
J1-v0v'
27 88% n.a.
28
2.0%
1%
29 94%
3.0 97% -1%
7% m.d.
.L,0
m.d. 3% 5% 2%
-'p
2% 2% 2$
it. d.
m"c.id.
'-p
m.d.
4% 2% 2% . 1% 2%
2% 2% 3%
5-V,9p'
m.d.
2%
m.d. m.d. m.d. m.d.
nd.
m.d.
-'p
m.d. 2%
2%
24$
m.d. m.d.
m.d.
m.d. 2% m.d.
4% 3%. m.d..
:3%
3% m.d. m.d. m.d.
mA.
mUd...
m.d.
ii. d.
m.d. m.d. m.d. m.d. 2% m.d. m.d. m.d.
2% m.d.
I7% !
m.d. m.d.
3%
5% 3%.. m.d. m.d. m.d. 19%
ml. d.
2%
U....
ZnO ZnUd ZnUd K,S
CaCO3 x
INTERNAL 0772
ITA-LG 00201
Product
33
34
j6
37 38
39
/40
42 43
144
.
45
46
47 48
49
50
-51
52
53 54
56
Cr, -
58 59
.
Tale
-'4afl7nip$d
55% 78% 78% 79% 38% 87%
9/4%
66% 81%
89%
m.d.
65% 48%
100% 88% 100%
.95%
100% 85%. 90% n9('od0ld%v
86%
t7P
96% 90%
Page 2
ChlorIte
4o%
(/0
5%
4% 50%
5%
3% 25% P'.1/d0 6% m.d.
11-.. d.
30% 40% m.d.
14%
m.d. 5% m.d. 8% 4%
--413. %Cd
7% 15% n.d, m.d.
Mineral Composition
PhiogoDi te
a:'
3% 2%
4rtz
2$ m.d.
4% 3% 2% 10%
2% 15% 5% m.d.
4% 2%
m.d.
3%
4%
2'-SL%I,
m.d.
3% 2%
m.d.
3% m.d.
m.d.
m.d. m.d.
5%
m.d.
2% m.d.
2%
m.d1
m.d.
m.d.
-m.d.
4% 2%
3% 2% 2%
m.d.
3% 2%
n,d,
5%
1%
n.xl.
Dolomite
8%
8% 3% 8%
Other
q
1.
7%
h-/0
m.d.
5%
5% 3%
m.d. m.d. 1n(4Id%, m.d.
4%
m.d. ii. d.
m.d.
m.d. 2% 4%
U. d.
2%
5% m.d.
m.d.
ZnO, K
a
INTERNAL 0773
ITA-LG 00202
B
but not more than (52)% by weight
a more than 1%,
Product
Mineral Coiirnosition
60
61 62 63
64
6
66
67 68 69 70 71
7723.
74
75 76
77 78 79
Talc
56%i%
89% 87% 84% 79% 85% 75% 78% 96% 26% 84%
86%
92% 75% 75% 91%
.
85% 86%
ChlorIte
30% 40% 2% 2% 5% 15% 5% 15%
1%
.1%
6o% 10% 5% 10%
n5%.d.
n.d.' 2%
5%
PhioRoDite
n.d.
2% Ql% 2%:
n.d.
3%
n1%.d. n1%.d, n.d.
3%
n1%.d,
2%
5% 4% 1% 4%
b<QuartZ
n.d.
3$
3% 4% 2%
n.d. n.d. n,d. n.d, n.d.
5%
'% 4
n3%d.
n.d.
5% 2%
4n%.d.
Dolomite TreolIte
7%
n18.%d, n.d.
3%
4%
25%d
n5%.d. n7%,d. rnd,
5% 5% 2-5%
ano.d% .
3% 2%
2% 2%
5% 5% 3%
2%
5%
4%
2% 2% 2%
3% 2%
2%.
3% 3% 5% 3% 5% 3%
t
- -)
INTERNAL 0774
ITA-LG 00203
C. Products having small aotrnts of Ohrysttile but not more than (3E2)% by weight.
more than i%,
Product
Mineral Compoattion
Talc Chlorite
Phlogopi. te
Quortz
Doloint te Chrvsotl le
80 40%
81 8o% 7%
82
83
76%
Q.Lft
12%
.09
84 87% 4%
85
83%
5%
86 U 1,0..
n10.d. ..1)-tI,l
..Lfl
2%
4%
n.d.
ri.d.
n.d. - 4%
- n.d.
4%
3% 4%
3%
8% 4%
''j-1,p10
.3%
4%
-c'cp,
2%
4%
S
INTERNAL 0775
ITA-LG 00204
CD,. Products having small amonnts of both Tremolite and Cthrysotile
more than %, but not more than (32T% of each by weight.
Product
Mineral Conosition
Talc Chlorite Ph1ogoite c+Qiiatz Dolomite Tremoilte Chrysotfie
87 28% 50% 88 61% n.d. 89 68% p 90 55% n.d. 91 23% 1% 92 61% n.d.
93 55% 1% 94 4%
95 873 n.d.
n,d, n,d.
3% b%
3%
14
3% n.d.
k%
5% 8%
7% 69% 6% 6%
6%_
5%
12% 25% 10%
3% 20% 25% 35% 4%
Li.%
k%
5%
51%4
5% 5% 4% 2%
2% 5%
5% 5% 5% 5% 4%
2%
4
INTERNAL 0776
ITA-LG 00205
E. Products having substantial amounts of' Chrysotfle and./or
Iliemolite -- more than c5t2)% by weight.
Product
flneraj. Composition
Talc Chlorite Phlogotite -Quartz Dolomite Tremolite hrysotile
96
66% u.d.
3%
97 31% 1%
1%
98
39% n.d,
3%
99 37% 3%
3%
100 78% 7%
%
10]. 53% 8%
3%
102 65% n.d. nd.
6%
5%
li.o%
n.d.
7% 3%
7%
35%
6% 6%
2%
L%
15%
8% 12%
2%
3% 3%
25%
10%
10% 15%
10%
8% 6%
7%
Pg t;
INTERNAL 0777
ITA-LG 00206
NOTES P&TEEt'U3ULATEDDATA
1. A1D. products tested were standard and commercial brands, purchased in drug stores or the drug departments of department storS or super-markets tn the cities of Washington, D. C., New York, and Boston.
fl data are based vpon continuous scan x-ray powder
diffraction vatterns. The precision, Intents of average devla-
tion, is of the order of rnaznitu4e of 2$ absolute for each of
the mineral SCCiCS reported. The data are given ft units of per-
centae composition by we.ght.
The lImits of detectabIlity by the method employed are
of the order of magnitude of 1 to 2% by weight for each of the
mino.al specles cited.
-
-
l. A.
Where an asbestiform mineral was Indicated by the x-ray
-pattern as bein present to a definitely detectable extent, its
presence was verIfied by the use of optical microscopy to dIe-.
close the presence of significant numbers of fiber particles.
B. Where the asbestiform mIneral was indicated by the x-ray pattern as being present at the just barely detectable level, \ this tas verified (or reeoted) by emDloylng the step-scan tech-
nique over the regions of the questIonable diffraction peaks.
5. The following mInerals were estImated by comparing the sum of the integrated IntensIties at the diffractIon angles
listed below, with the corresponding summed Integrated Intensities at the same angles of standards composed of the pure minerala
Mineral
Twd-Theta Values Si'ied
Thlomlte
'X-Quartz chlorite Phlo.goplte
31.0 - 31.2; k4.8-4-5.0.; 20.4 - 20,6; 26,6-273O;-.39.3-39.7;
6.j-6.5;. 12.4-12.8; 19.019.2-L25.025.4 8.6-9,O 25.9-26.1; 28.l-28..3( -
6; Only two of the asbestiThn miherals were detected is
the products tested. Each of these was estimated by .compariso
with standards made up by taing the pure mineral flth pure talc
in various proportions by weight. For both unknowns and standards,
the parameter measured was the ratio of the integrated intensIty
of a diffraction peak relative to that of an inte'nal standard.-.
ZnThe internal standard employed wa 5% by weight of
(QH)Ci,
The Integrated IntensIties were sumea at the following diffraction
angles;
Asbestiform Nineral
Chrysotile
Trernolite
Two-Theta Values Snmed
12,0 - 12.4; 24.3-21F.3 10.4 - 10.Gt 27.4-27.6, 29,1Fs29,7;
30.6-30,9 33.2-334
INTERNAL 0778
ITA-LG 00207
Talc was doterthned by difference. The fclloring abbreviations are employeda
n.d. not detectable
ZhQ zinc oxIde
ZbLJ4 = zInc trndecylenate
K kaolIn S = starch
= calnte x phase not identified because deemed
unhiportant. In several Instances, the same brand of product was purchased In different places at different tlrneS to check on the constancy of compositlon of the mineral thxture. Considerable variatons, ere found. See product numbers 1L. and 15;. 22, 22
and '3>bther instances: constancy wIthin the precision of
the analytIcal method t-as observed (e.g., In the case of product No, .7).
INTERNAL 0779
ITA-LG 00208
Product Nmber
1
2
3
4
7 8
10
11
12
13
114.
15 i6 17
18 19 20 21 22 23
2k
25
2.6
29
30
31 32
33
3$ 36 37
39.
40
KEY TO PRODUCT NAMES
Product Name
AMNENS POWDER, MEDICATED
ANOLIN DEODORANT POWDER
AQUMIARINE COOLING SPRAY BATH
POWDER
BAGATELLE AMBER -DUSTING POWDER
BOURJOIS BATH POWDER
OALDESENE MEDICATED POWDER
CASHMERE BOUQUET BODY POWDER
HLNEL NO. 5 BATH POWDER COUNTESS ROCHEAU CAME DUSTING
POWDER
-
CREPE DE CHINE DUSTING POWDERJ
MILLOT
CREPE DE CHINE POUDEE MIST,
MILLOT
-
CUTICUBA TALCUM POWDER
DESENEX
DESITIN B1BY POWDER
DESIflN BABY POWDER
DIAP.ARENE BABY POWD
DOROTHY GRAY "SECRET OF THE SEA"
DUSTING POWDER
EMEPSAUDE TALCUM POWDER
ENGLISH LE&tPEER
-
FABERGE tIC" DUSTING POWDER
FRIENDSHIP GARDEN DUSTING POWDER
FRIENDSHIP GARDEN DUSTING POWDER
FRIENDSHIP GARDEN DUSTING POWDER
HEAVEN SENT AEROSOL BATH POWDER -
141ST
HEAVEN SENT BATE PO-iJDER
HELEN PRESSL "LITTLE LADY" IFiPORTA, SPAIN NENS' TALC
ISIS PLOP 8.L 'nLCm4 . POTJDFR
JOZthOsJ10 BABY POciDER
JOHNSQN AND JOHNSON NEDICAThI)
flWDER
-.
p KOSCOT BEAUTY DUST--OIL OF MINK
WIVIN ARPEGE DUSTING POWDER
LAEVIN ARPEGE ROWDERED MIST
LNVIN APAPEGE TALC
f LEWIS BABY POWDER
LOVES FRESH LEMON GLOSSY POWDER
MACY' S SCENTED BOPSATED TALCUM
a MACI'S TALCUM, APPLE % NARCELLE DUSTING POWDER, TIPO-
ALLERGENIC -
MAR! CHisaS PERFUMED -DtJb'TING
POWDER
-
Further Identification
Brl.stol-Myers (No. Ins)
Norwich
-
Revlon (111.3) Corand (DCII)
Pen.nwalt (5274) Colgate-Palmoliv
-
Jergens
House of Fragrance (Ln,2:
House of' Fragranoe Purex (07170)
WTS-Pharmacraf t
Pfizer (1139Z) (3/29/72)
Pfizer (nSA) (5/10/72) Breon (E1OO)
Coty (355-4010)
Hem
-
(2891)
Shulton (3/27/72)
Shulton (5/9/72)
Shulthn (7/13/72)
Rubins teth
Rub tile t em
(028Q) (3612)
(l88)
Manley & James
a
INTERNAL 0780
ITA-LG 00209
Nivnber Product Name
Furthr Identification
41 MENNEN BABY MAGIC POWDER
(B112)
42 gENNEN QUINSANA FOOT POWDER
(H202)
43 flEEGK TALC, PRODUCT NO. 6460, LOT
NO. 6460)
(8039301)
4Zj. PIEXSA.NA 2387-D MEDICATED POWDER Plough
45 OLD SPICE BODY TALCUM
Shulton
46 PERSIAN LILAC DELUXE DUSTING
POWDER
April Showers (LFN)
47 PERSIAN LILAC SPRAY BATE POWDER April Showsrs (B2003)
48 POND' S PERFUMED TALC BODY
DEODORANT DREAM FLOWER
(1152)
49 PRINCE MATOHABELLI BELOVED SPRZIY
I POWDER
50 QUEST DEODORANT PO;DER
51
EPLIQUE SPRAY BATE POWDER
Parfums Raphael (004)
52 BIVIANA FOODS - ITALIAN STEABIN TAW For Rice
53 SEPTE?IBER hORN BY POND'S
(19B)
54
SEVEN WINDS AFTER RATE TALC
DuBarry
(021035)
55 USPTALC
56 VASELINE INTSIVE CARE BABY POWDER
(I 209)
57 YVES SAINT LAURENT RIVE GAUCRE SPRAY TALC
58 59
tE P BABY POUDER
ZEASOEB SUPER ABSORBENT MEDICATED POWDER
Stter(et1lO21)
6o AHBUSE-DMIA DUSTING POWDER
61 APRIL. SHOWERS
62 AVON UNFORGETTABLE PERFUMED TALC
(9884)
BELOVED PERFUT'UD DUSTING POWDER, PRINCE NATCEABELLI
64 COfl FACE POWDER HACEEL
65
DESERT FLOWER SPRAY BATH POWDER
Shultozi (F 1 EKI)
66 - ENERAUDE DUSTING POUDER 67 EFiEPAbE SPRAY DUSTING POWDER
Coty Coty
(1 AEY)
68
FABERGE FLA?EAU DEODORANT SPRAY PO'DER
(37 WBF)
69 flAil NATE SPRAY BATR POWDER
(1 N 247)
70 JEllS TALC, FLESH
71 4OLIE MADAME DUSTING POWDER, BALNAIN
72. tADY ESTHER FACE POWDER, RACHEL
tx FACTOR FACE WE, flACLLE
PIEDICATED CONFORT POWDER
. Parke-Davis
75 OH! da LONDON TALC
Yardley (498)
76
TO KNOW NE IS TO LOVE ME - T-INXERBELL
Thm Fields, Ltd!
77
OUCH AND C-LOW PACE POWDER, CEEMIY PEACU
Revlon
78 TOUJOURS Z'OI BATE POUDER
. Corday
-79
!AP.DLEY APRIL VIOLETS
..
(4908)
80 cHANTILLY DUSTING POWDER
Houbigant 111V\
31 .QASErIERE BOUQUET
.82 .E.J NATE TALC
83 MEI'iNEN BRAVE TALC
(fl81)
SHOyJER TO SHOWER 'DY POWBLI
Johnson & Johnson (55O7
85 PURE BABY POWDER, DAaT DRUG
(K:11C)
86 POND'SDREA5 FLOWER PERFiThIED TALC
( 3D)
4-
INTERNAL 0781
ITA-LG 00210
Product Number, Product !Thme
Further Identifi catIon
87 88
1
89 90
/
91
92,
93
9 95
ALMAY HYPO-ALLETtGENIC PACE POWDER
CONSTANCE CARROLL, BOUQUET TALC
DJER-KISS TALCUr4
FLA?4TPGO DUSTING POWDER, PUSSY
LANDEH LIlACS AND ROSES TALC
MAVIS TALCUM
MAVIS BODY POWDER
TANGEE
C
ZBT BABY P0gDER
Kerkoff (L1O7)
Vlvaudou Vlvaudou
Ltift-Tangee (300k8)
96 BLANHARD 'S DUSTING POWIER
97 BORN WILD DUSTING POWDER
Del Labs
98 LMJDER GAEDE2JIA AND SWEET PEA TALC
99 LANDER LILACS AND ROSES DEODORANT BODY TALC 100 j4156 flOE DUSTING POWDER
101 Tfl WINDS SPAY TALC
(Avon (Dcc 1272
2-lk-72 ,HWS)
102 TOSA DUSTING POWDER
P2AP II
INTERNAL 0782
ITA-LG 00211