Document 7dj9Z44LDYdZbvzaarM6JvEo

AR2260319 SOIL ADSORPTION (METHOD DEVELOPMENT / PILOT STUDIES) TEST SUBSTANCE Identity: N-ethylperfluorooctane sulfonamidoethanol; may also be referred to as N-EtFOSE Alcohol or FM-3422. (1-Octanesulfonamide, N-ethyl1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-N-(2-hydroxyethyl)-, CAS # 1691-99-2) Remarks: Material is an off-white, waxy solid of uncharacterized purity. METHOD Method: The attached studies explore the useof organic solvents (1977 study) or Thin Layer Chromatography Plates (1978 study) for determining the soil mobility of N-EtFOSE alcohol. These methods were developed by 3M while looking for altematives for studying the adsorption/desorption propertiesofthe test substance. GLP (Y/N): No Year (study performed): 1977 and 1978 Statistical methods: None. "Temperature: Not noted in the reports. Remarks field: Very little detail is available on these study methods. RESULTS "The 1977 study using 20% and 5% alcohol as a portion of the solvent indicated between 64% and 98% of the N-EtFOSE alcohol was sorbed to the sandy loam soil. The 1979 study using TLC greenhouse soil plates indicated that N-EtFOSE alcohol did not move from the spot it was placed. INC SIONS Both studies concluded that N-EtFOSE alcohol islikelyto sorb to soil. Submitter: 3M Company, Environmental Laboratory, P.O. Box 33331, St. Paul, Minnesota, 55133 DATA QUALITY Reliability: Klimisch ranking 3. These studies lack sufficient explanationof the methodologies. Purity of the test substance is not characterized. The analytical methodology is also either missing or lacks validation. REFERENCES 006210 Method and results summary, "Adsorption of FM-3422 on Soil." Stephen K. Welsh, March 7, 1977, April 12, 1977, May 9, 1977. Excerpt from 3M Technical Notebood No. 48277 30, "Soil Thin-Layer Chromatograph--y FC 95, FC 143, FM 3422", Page 30, A. Mendel, Project Number 997061200, October 13, 1978 Review of Technical Notebook No. 4827-30. Soil Thin Layer Chromatography. Professor Stephen A. Boyd, Michigan State University, May 19, 1993. OTHER Last changed: 5/18/00 006211 FAtCt1a4c3h,edFMa3re42c2o.mmAe.ntMsenodnet,hePr3oMjecTtecNhon.ic9a9l7R0e6p1o2r0t0"3SoMilTTehcihnniLcaayleNroCtherboomoaktoNgor.a4p8h2y7-7,FCPSag,e 30, Oct. 13, 1978 (one page from a technical notebook)" made by Professor Stephen A. Boyd, Michigan State University, dated May 19, 1993. 006212 Reviewof Technical Notebook No. 48277-30 Soil Thin Layer Chromatography Tam not too sure at the origin of how useful these plates are. the thin layer plate where Apparently both FC they were originally 143 and FM 3422 remained spotted. This implies no movement insensitive, with and the water used to doesn't yield much develop the plate, useful information. Basically this tells me the method is That is because FM 143 has a much Tower soil sorption coefficient (K., = 17) than FM 3422 (K,. = 15,000) and yet they behaved similarly in the soil thin layer chromatography plate. eMxopbeirliimteyntsst.udiTehsesaereareprmoobarbelydiffbiecsutlt done to do einxpesroiilmenctoallulmynbsutuwsoinugldmyiiceilsdibmleorediusspelfauclemdeantta that could be compared to established now and there other well are several slatbuodriaetdorcioemspdoouinndgs.thisThtyepeexopferwiomrekn,tailncalpupdrionagchmyis well own. `These experimetns augment batch equilibration (isotherm) experiments very nicely. 006213 PACE sgl No. ATRL ZEER 3M TECHNICAL NOTEBOOK. No. subject: SOIL THIN- LAYER Date: {0-13-78 LHROMRATRERAEHY - FCASS RT, FR3122 Object: TR LOAT LLANE PLATE Toe else Eee, BoMenSel o Teel Report 1/7)79 0 Reference: 42hBH1-2 mm VARIBUS S0ILS WERE S(EVET EARLIER BY MT. ELVABRRAWY Avn (Twhs ZQUND EMPIRICALLY THAT THE 250 mizROM TE SAIL PARTICES (JHEN SLURRED WH WATER ANT CARTED Ae GLASS PLATES GAVE Bonn' Que ARLE ALATEY, AN ALIDRBINLLY THE FELLOWIWEG WRG DEVE, (WTIMATE MIXTURE QF 150g, oF 250 MECADN-SIEVET GREEN- AusE SO LORTRVED FROM Ww. BERE RERIIMEM ANT SQL EVED BY (TE AND LH. pRTEHARD) AND HD mL, WATER WAS WEL-SHRAKEN ANT SPREAD eta TEN (0x20 Cm, WATER TO MAKE MruRE GLASS SUGHILY PLATES [vert ESS ViBLOUS mime TRY usw 85-90 me ANT FEARERDING may Be HuEHTLY AlckeR], THE PLATES WERE RWAWED TO A(R TRY. THE SPREADER SED Tn (REA IVE LORAT ree PLATES WAS VESEBNED RHDE- 200] Ave A.MevTeL BY TR. Tw BEUBLE, BG. BUTHRIE LB 3/18 ONE oF THE BETIEM are AWLO (0KF0 rm PLATES Wes SPOTTLT 2em LRBEET EC 96 (seer mine) Fo v3 {mune FRUM THE dang em FUE (Ruse nme, ws ane views eure) Sears were OPE G1 CavmiE SENRRNTT, THE PORTE WAY TRUELUIER 100 MA (v F FILTER PAPER Luntmay vo, (1 - unes rok AEAUT paEsAruant (MR HO Mov over TRY] THE PLNTE WAS WITH WATE FIR TRIED, RK. THE TRVELIFMEST (TWAS WATED THAT REauireED whew THE SO. TLC PLATE WAS PLRLET (MTE THE TANK LONTRININZ ARLLT |LATEER LATER, THE SQIL IF THE WATER GARDUALLY FELL FAD THE FLATE BUT THE DIR Vor See rH " ren Te Seencanna Aaeas. Bet | HE BLRTE PURETRYS, wee (es), PTLaReEEDTevBNearY-eRdAYPEurwem(k(iwRsBuyRCIHVEELNapferszwBYmeLsa)RgAyNGSErAPaOS,E AaAicue MY SugwEy Twar Foil AVS Em a422 pio war pemve BRIG THE SPAT = TUE TCOO_mFPLa-Hn5TSydMsERv8UNFEANWTEEADRR 1LGOVGRECEnTTARTAATI,ENTHOS EF Law u RAa DIOTAICr ETIWVIETm RY EBF | FS -- -- 2 lelrg TS "rSTCOPY AVAILABLE -- --_ a-- --_-- 006214 wren; s (;andi( Reh 9 Uranomeee 096209 pull 12,078 PS /75N )A) -- KAo)iniaela.il , < \ PU . et Trgiisag 1%v sit 367% : ay 1% . 2 we Wath: 25% ADSORPTION OF FM 3722 (in C-206) ON SOIL, 12/30/75 TEC Soil Is3 megfoos - sandy lous, 40673, pi 17; air dried I. 2. Hpaokye0upmlsolfultaisoknsspuotf FC-206 in 100g soil DI water at 600 ppm, 6,000 pps, and 60,000 and 100 ml of the following solutions: FFllaasskk Flask 11888 18C -- D660I,00"w0a0ptpemprpFmC-F2C0-0206 Flask 18) - 60,000 ppm KC-206 33. SThaatkSeofil"aeskctftoer 2a4ndhoduercsantatof100theoscliilqluiadt.ion/Cmeinnturtief.uge the liquid. F-206 Cone. 11.3723 conc, ppm Equi. B-3722 conc. C, ppm IT(Im2easuardesdo)rbed, fm, pale (calculated) RESULTS (12/30/75) DI Water 600 ppm 6,000 ppm ~ wa -- 0.14 2.2 a " 60,000 ppa a0 210 20 v 4 Adsorbed ----- 98 9s 50 HosorrTion oFEEERZIG S01, 3/7/77 \ Soil - sandy loam, 40673, p. 17; air dried # ; Sotvont 2200 aleonol in' DI water 1. 2. PTlueteksea iofrewLaomntgdteF1M35d13i2422t2ustoi(toLtnoltso.o67fa6n)dthod.iencsattnohtceksoofslfovleutnthteionsanudwpietsmhhaatktaehnetfosra(mtehaetsoslltevoaecsnktt.s24olution). 3. 4. PDPeIuootuwra2tt0oaeginrFk,s.ocishlehaShwkiaeankteeet.arhcotharhnoeduogfthualb4dey-ds,5.02a0fnmoldmrlcc2e4oennftthrortiuhiferfusuggseea(m1pft0lui0bev-ee1s2s,0omliuntotuhstiecneoisnlslfaaittlslino6dn,t/0h2a0e0i0nmt.lur)bp.eDsI ww(ia4tt,he0r00inG). 5. Afver shaking, centrifuge as above and pour off tho liquid. WSUTS G/T wy wh FN 3422 conc. ppm (measured) DL Water 25 18 0.19 Equil. Conc. C, ppm (measured) --- Ls ode 0.07 + Adsorbed . -- Adsorbed, x/m, pg/g (calculated) --- 21 1.6 uw 0.12 "006215 5 ADSORPTION -OF FM 3422 ON SOIL, 4/12/77 SSooillven-tsa-nd5y% alolacno,ol406i7n3,DIp.wat1e7;r air dried. 1. FPuMt 3a422fewsetntgleFMan3d422deciannttheoffsoltvheentsupanedrnasthaankte f(otrheatstolcekastsol2u4tihoonu)r:s. Let 2. CMaeknetri1f0u%geandat 1310d,i0l0u0tiropnnsfoofr t1h0emisntuotceks.Solution with the same solvent. 50 Put 20g soil in each of 4-50 ml. centrifuge tubes, then fill the tubes 4. wTiotuhr oDIffwattheer,vatsehrakeandthoardodug2h0lym,i aonfdthceentsraimfpulegesoatlut1i0o,n0s00anrdpm20forml 10DI min. water in the blank. Shake the tubes for 24 hours (100-120 oscillations/ 5. mAifnt,e)r. shaking, centrifuge as above and pour off the liquid, RESULTS (4/12/77) FM 3422 conc. ppm (measured) DI Water a s.9 os Equil. conc. C, ppm (measured) -<- 08 016 0.08 Adsorbed x/m, pg/g (calculated) --- a 5.7 0.42 . + Adsorbed --- 9% 9 " ADSORPTION OF FM 3422 ON SOIL, 5/9/77 Soil - sandy loam, 40678} p. 17; air dried & 3 Solvent - 5% alcohol in DI water - hi 1. Dissolve 50,0 ng FM 3422 (Lot 676) in 50.0 ml alcohol. Put this solution 2. tLiehntotobtohatetoonsmeh)ovleiCte"enretmruvilofsluiugomene"trsioscnteanadnofd.ftmohraekefsiuvuepperdtanoyastm.aanrtk (awAtiwthh1i0tD,eI00w0faltroecprm.spfpoersr1e0dmiinn. 3. 4. MSPauoktleve2n07t5g.%,soi5l0%,in25e%a,chanodf 10% dilutions of the stock solution 6-50 ml centrifuge tubes, then fill with the same the tubes with 5. 5Ptho,eu0r005%oftfapnl.ctohheolsoslovlevnetnta,ndsahdadke20thmolrouogfhltyh,e and centrifuge five minutes at sample solutions and 20 ml DI water in the blank. Shake the tubes for 24 hours (100-120 oscillations/ 6. Amfint.e)r shaking, centrifuge (5,000 rpm, min.) and pour off the liquid. RESULTS (5/9/77) 4 3422 conc., ppm (measured) DI Water 3.1 2.25 LS 0.64 0.38 J Equil. conc., C, ppm (measured) == 0.06 0.05 + 0.02 0.02 Adsorbed, x/m, pg/g (calculated) + Adsorbed --- 30 2.2 eos os . 0.62 0.36 + 97 ss 0062 * Dropped the sample co 1