Document 7RM6Jb1bGdpqpnwzdov346OBg

WJHUIC`HVXXV- V'-'K'*.-, :.D ittaiaaiM M N iN i A. \> Sept. 30, 1924. ' Mr. if. P . Y a n t, U .3 . B ar. o f Mines Experiment S ta tio n , Pittsburgh, Pa. \ -4 0 ^ ' -c My deer S i r : I hare examined the d r a ft of the proposed Report on E th y l G asolin e In v e s tig a tio n s and wish to make c e r ta in ooaments s e r ia tim as per pages o f my oopy th e r e o f: P . 8 . The wording in the beginning o f th e la st fa r . is not olear. P* 9 . I-eferenced to ^ a ir h a ll 1 and \very should b fo o t-n o te d * p. 13. (below center) "percent of to ta l lead in g a so lin e used in dep osits 8 0 .6 *. This statem ent i s not oleur Pe 14# I t does n o t appear to me t h a t the heading given fo r "Table 4" f i t s the contents of th e T able. Also ( r ig h t ce n te r ox p a g e ), I b e lie v e a date should be put down fo r the "Bad" of th e ' average weights T a b le , ^ la o , in la s t Table on ih is page, th e word " l b s ." probably ought to b e specified# clear. P . 16. The wording o f th e f i r s t sentence is not P . 16. 3rd P a r . , X would su g g est that the s p e c i e s of animals showing polychrome t o p h i l i a be mentioned. P . 17. (Par. just below center of page, la s t se ntence), I would su g gest the f o l l o w i n g wording "where i t is jw^llowed or otherwise e l i m i n a t e d , " ^ there are two or three c nce iv ab le meth65s o11 r than e x p e c to r e t io n by which the animals might fr e e the passage ways of f o r e i g n m atte r. P . 1 7 - . (Rabbits - Guinea pigs - Doga - Ifankeys Sunwiary)* Ti-ere ar e ao meny typo graph ical errors upon the pages o f my copy tht t I have found i t inadvisable to oornneut upon them at this time. 2 In regard to symptoms o f lead p o iso n in g , I would su ggest tha t th e fo llo w in g hav< n e g a tiv e values and mention o f them should probably Do in c lu d e d : m iso a r r lu g e s, a n o re x ia , trem ors, in c o o rd in a tio n and anem ia. I t is also understood. I b e lie v e , th at the s tr e e t dust and d rip p in gs an a lyse s are to be in c lu d e d . Also a passage upon delayed symptoms o f lea d p o ison in g (a d r a f t fo r tfiich i have already forwarded to Dr. S a y e rs). On th e whole I think t h is t e n t a t iv e d r a f t is oomprehensive in th a t i t appears to touch upon and to answer most o f the q u estio ns which w ill be a p t to a r is e in the minds o f the p u b lic and o f fa ir-m in d ed o r l t i o a . The n e x t general oonferenoe. I tr u s t, w ill r e s u lt in gettin g i t s rough p la ce s ironed out and th e m a te r ia l p r e t t y w e ll in to shape fo r a p relim in ary re p o r t. Tours very t r u ly Copy to - Dr. K . h . Sayers D r. Graham Hdgar 7;; -2 9 COUJ5CB OK M B W C C fl! D B P A T U K T OF PU BLIC HEALTH E. V. McCAMPiiELiXi, P I.D ,, M .D. E M E R Y H . HAYH TJR 8T, P R O )., M .R. JA M E S S. W ILSO N , M .S., M .D , NORM A SERRER T, B .9 ., Tt.N. L. H. V A N B tJSE IR K , B .S ..M .D . '-T-ETE O H IO S T A T E tJJV J. VJ K SIT Y W . O. T H O M P SO N , PniWlimiWT GOLUMBITS Sep t. 29t 1924. Dr. R. R. Sayers , U.S* Public Health Servioe, Washington, D .C . Dear Dr* Sayers; D r. Graham E d ga r, D ire c to r o f R esearch, E th y l G asolin e co rp o ra tio n , to idiom I subm itted th e fo llo w in g paragraph co n sid ers i t ,Tmos t s a t i s f a c t o r y : " Delayed lead p oisoning, or that con d ition in which exposed persons or animals may have absorbed and re ta in e d lead w ithout immediate symptoms, b u t with symptoms e x h ib ite d l a t e r , i s f u l l y recogn ized by a number o f a u th o r i t i e s , in f a c t , th e symptoms of lead poisoning may come on years a fte rw a rd s , probably depending upon some change in th e a c id -b a s e e q u ilib riu m of the tissue flu id s in the body. S u ffic e it ito say th a t in a l l o f th ese ins tare ea lead has been d e fin ite ly sto re d , u su a lly in large amounts, in th e body t is s u e s . According to />ub and o th e r s , th is sto rage lias been found to occur to the extent o f 80 per cen t in th e s k e le to n . O b vio u sly, without evidence o f sto ra g e or dep o sitio n of lead in the tissues follow in g exposure to e& iyl gasoline exhaust fum es, the p o s s i b i li t y o f delayed symptoms from lead poisoning from th is source may be dism issed as untenable. As you w i l l r e c a l l i t was l e f t to me to devise a statem ent along the line indicated fo r the rep ort on E th y l G asoline hazards. The statem ent o f course should come befo re The Conference Committee fo r such actio n as i t sees f i t . Yours very s in c e r e ly , 72-29 E . B . sayh s t , M. D. Consultant, E th y l Gasoline Corporati on /